SIMILAR PATTERNS OF AMINO ACIDS FOR 2Q9R_A_BEZA203

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c41 LUMAZINE SYNTHASE

(Magnaporthe
grisea) 		PF00885
(DMRL_synthase) 		4 LEU A  33
GLY A  36
ILE A  20
ILE A 117
 None
 0.86A 2q9rA-1c41A:
undetectable		 2q9rA-1c41A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)

(Lactobacillus
sp. 30A) 		PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C) 		4 GLY A 307
PRO A 345
ILE A 347
ILE A 337
 None
 0.85A 2q9rA-1c4kA:
0.0		 2q9rA-1c4kA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)

(Aspergillus
nidulans) 		PF01761
(DHQ_synthase) 		5 LEU A  10
GLY A 151
PRO A 170
ILE A 173
ILE A   9
 None
 1.35A 2q9rA-1dqsA:
0.5		 2q9rA-1dqsA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3j NADP(H)-DEPENDENT
KETOSE REDUCTASE

(Bemisia
argentifolii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 173
GLY A 257
ILE A 230
ILE A 233
 None
 0.83A 2q9rA-1e3jA:
undetectable		 2q9rA-1e3jA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebv PROSTAGLANDIN H2
SYNTHASE

(Ovis aries) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 LEU A 534
GLY A 227
ILE A 337
ILE A 341
 OAS  A 530 ( 3.3A)
None
None
None
 0.81A 2q9rA-1ebvA:
0.0		 2q9rA-1ebvA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ejb LUMAZINE SYNTHASE

(Saccharomyces
cerevisiae) 		PF00885
(DMRL_synthase) 		4 LEU A  34
GLY A  37
ILE A  21
ILE A  87
 None
 0.83A 2q9rA-1ejbA:
undetectable		 2q9rA-1ejbA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyp CHALCONE-FLAVONONE
ISOMERASE 1

(Medicago sativa) 		PF02431
(Chalcone) 		4 LEU A 201
GLY A  31
ILE A  84
ILE A 192
 None
 0.69A 2q9rA-1eypA:
0.0		 2q9rA-1eypA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fts FTSY

(Escherichia
coli) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 LEU A 235
GLY A 455
ILE A 278
ILE A 248
 None
 0.87A 2q9rA-1ftsA:
1.0		 2q9rA-1ftsA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hlg LIPASE, GASTRIC

(Homo sapiens) 		PF00561
(Abhydrolase_1) 		4 LEU A 131
GLY A  97
ILE A 138
ILE A 135
 None
 0.68A 2q9rA-1hlgA:
0.0		 2q9rA-1hlgA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0a 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
DEAMINASE

(Pyrococcus
horikoshii) 		PF00291
(PALP) 		4 LEU A 321
GLY A 261
ILE A 266
ILE A 267
 None
 0.87A 2q9rA-1j0aA:
0.0		 2q9rA-1j0aA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k8q TRIACYLGLYCEROL
LIPASE, GASTRIC

(Canis lupus) 		PF00561
(Abhydrolase_1) 		4 LEU A 131
GLY A  97
ILE A 138
ILE A 135
 None
 0.80A 2q9rA-1k8qA:
0.1		 2q9rA-1k8qA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kz1 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Schizosaccharomyces
pombe) 		PF00885
(DMRL_synthase) 		4 LEU A  35
GLY A  38
ILE A  22
ILE A  84
 None
 0.84A 2q9rA-1kz1A:
undetectable		 2q9rA-1kz1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1q ADENINE
PHOSPHORIBOSYLTRANSF
ERASE

(Giardia
intestinalis) 		PF00156
(Pribosyltran) 		4 LEU A 174
GLY A 168
ILE A 137
ILE A 152
 None
 0.64A 2q9rA-1l1qA:
undetectable		 2q9rA-1l1qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1llu ALCOHOL
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLY A 306
PRO A 141
ILE A 149
ILE A 152
 None
 0.86A 2q9rA-1lluA:
undetectable		 2q9rA-1lluA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqs SLY1 PROTEIN

(Saccharomyces
cerevisiae) 		PF00995
(Sec1) 		4 LEU A 261
GLY A 232
PRO A 587
ILE A 213
 None
 0.83A 2q9rA-1mqsA:
undetectable		 2q9rA-1mqsA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n60 CARBON MONOXIDE
DEHYDROGENASE LARGE
CHAIN

(Oligotropha
carboxidovorans) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 LEU B 798
GLY B 802
ILE B 478
ILE B 668
 None
 0.81A 2q9rA-1n60B:
undetectable		 2q9rA-1n60B:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ndf CARNITINE
ACETYLTRANSFERASE

(Mus musculus) 		PF00755
(Carn_acyltransf) 		4 LEU A 551
GLY A 573
PRO A 568
ILE A 576
 None
 0.83A 2q9rA-1ndfA:
undetectable		 2q9rA-1ndfA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nnw HYPOTHETICAL PROTEIN

(Pyrococcus
furiosus) 		no annotation 4 LEU A 118
GLY A  71
ILE A  76
ILE A  77
 None
 0.84A 2q9rA-1nnwA:
undetectable		 2q9rA-1nnwA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ort ORNITHINE
TRANSCARBAMOYLASE

(Pseudomonas
aeruginosa) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A   9
GLY A 128
ILE A 324
ILE A 327
 None
 0.83A 2q9rA-1ortA:
undetectable		 2q9rA-1ortA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p22 F-BOX/WD-REPEAT
PROTEIN 1A

(Homo sapiens) 		PF00400
(WD40)
PF12937
(F-box-like) 		4 LEU A 426
GLY A 428
ILE A 433
ILE A 412
 None
 0.85A 2q9rA-1p22A:
undetectable		 2q9rA-1p22A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smq RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SMALL CHAIN 1

(Saccharomyces
cerevisiae) 		PF00268
(Ribonuc_red_sm) 		4 GLY A 229
PRO A 291
ILE A 295
ILE A 299
 None
 0.84A 2q9rA-1smqA:
undetectable		 2q9rA-1smqA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1spi FRUCTOSE
1,6-BISPHOSPHATASE

(Spinacia
oleracea) 		PF00316
(FBPase) 		4 LEU A  95
GLY A  99
ILE A 103
ILE A 104
 None
 0.83A 2q9rA-1spiA:
undetectable		 2q9rA-1spiA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0m PUTATIVE POLYKETIDE
SYNTHASE

(Streptomyces
coelicolor) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 LEU A 136
GLY A 142
ILE A 102
ILE A 133
 None
 0.77A 2q9rA-1u0mA:
undetectable		 2q9rA-1u0mA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xec DECORIN

(Bos taurus) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		4 LEU A 247
GLY A 222
ILE A 204
ILE A 228
 None
 0.83A 2q9rA-1xecA:
undetectable		 2q9rA-1xecA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zkj EXTENDED-SPECTRUM
BETA-LACTAMASE

(Klebsiella
aerogenes) 		PF00144
(Beta-lactamase) 		4 LEU A 283
GLY A 286
ILE A 343
ILE A 347
 None
 0.81A 2q9rA-1zkjA:
undetectable		 2q9rA-1zkjA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ab5 MRNA MATURASE

(Saccharomyces
cerevisiae) 		PF00961
(LAGLIDADG_1) 		4 LEU A 291
GLY A 313
ILE A 344
ILE A 345
 None
SO4  A 605 (-3.3A)
None
None
 0.80A 2q9rA-2ab5A:
undetectable		 2q9rA-2ab5A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d30 CYTIDINE DEAMINASE

(Bacillus
anthracis) 		PF00383
(dCMP_cyt_deam_1) 		4 LEU A  30
GLY A  40
ILE A  75
ILE A  73
 None
 0.79A 2q9rA-2d30A:
undetectable		 2q9rA-2d30A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddz 190AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF04017
(DUF366) 		4 LEU A 120
GLY A 137
ILE A  92
ILE A 113
 None
 0.70A 2q9rA-2ddzA:
undetectable		 2q9rA-2ddzA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dul N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF02005
(TRM) 		4 LEU A  67
GLY A   9
ILE A  60
ILE A  63
 None
 0.77A 2q9rA-2dulA:
undetectable		 2q9rA-2dulA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dyu FORMAMIDASE

(Helicobacter
pylori) 		PF00795
(CN_hydrolase) 		4 LEU A  78
GLY A  82
ILE A 119
ILE A 103
 None
 0.77A 2q9rA-2dyuA:
undetectable		 2q9rA-2dyuA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ehp AQ_1627 PROTEIN

(Aquifex
aeolicus) 		no annotation 4 LEU A  47
GLY A  68
PRO A  45
ILE A  78
 None
 0.87A 2q9rA-2ehpA:
undetectable		 2q9rA-2ehpA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fge ZINC METALLOPROTEASE
(INSULINASE FAMILY)

(Arabidopsis
thaliana) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 LEU A 540
GLY A 543
ILE A 905
ILE A 906
 None
 0.85A 2q9rA-2fgeA:
undetectable		 2q9rA-2fgeA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fr5 CYTIDINE DEAMINASE

(Mus musculus) 		PF00383
(dCMP_cyt_deam_1) 		4 LEU A  42
GLY A  52
ILE A  87
ILE A  85
 None
 0.82A 2q9rA-2fr5A:
undetectable		 2q9rA-2fr5A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gr9 PYRROLINE-5-CARBOXYL
ATE REDUCTASE 1

(Homo sapiens) 		PF03807
(F420_oxidored)
PF14748
(P5CR_dimer) 		4 LEU A  68
GLY A   7
ILE A  74
ILE A  75
 None
 0.79A 2q9rA-2gr9A:
undetectable		 2q9rA-2gr9A:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h8x XENOBIOTIC REDUCTASE
A

(Pseudomonas
putida) 		PF00724
(Oxidored_FMN) 		4 LEU A  45
GLY A  48
ILE A  19
ILE A  21
 None
 0.87A 2q9rA-2h8xA:
undetectable		 2q9rA-2h8xA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4q 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING 1

(Saccharomyces
cerevisiae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 LEU A 121
GLY A 144
ILE A  98
ILE A  96
 None
 0.86A 2q9rA-2p4qA:
undetectable		 2q9rA-2p4qA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pm9 PROTEIN TRANSPORT
PROTEIN SEC31

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		5 LEU A 252
GLY A 255
PRO A 235
ILE A 260
ILE A 237
 None
 1.14A 2q9rA-2pm9A:
undetectable		 2q9rA-2pm9A:
19.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q9r PROTEIN OF UNKNOWN
FUNCTION

(Shewanella
baltica) 		PF04222
(DUF416) 		5 LEU A  36
GLY A  90
PRO A  93
ILE A 194
ILE A 196
 BEZ  A 203 ( 4.1A)
BEZ  A 203 (-3.5A)
BEZ  A 203 ( 4.6A)
None
BEZ  A 203 ( 4.4A)
 0.00A 2q9rA-2q9rA:
37.9		 2q9rA-2q9rA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhs LIPOYLTRANSFERASE

(Thermus
thermophilus) 		PF03099
(BPL_LplA_LipB) 		4 LEU A 155
GLY A  89
ILE A 106
ILE A 110
 None
 0.80A 2q9rA-2qhsA:
undetectable		 2q9rA-2qhsA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhu LIPOYLTRANSFERASE

(Thermus
thermophilus) 		PF03099
(BPL_LplA_LipB) 		4 LEU A 155
GLY A  89
ILE A 106
ILE A 110
 None
 0.78A 2q9rA-2qhuA:
undetectable		 2q9rA-2qhuA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3u PROTEASE DEGS

(Escherichia
coli) 		PF13365
(Trypsin_2) 		4 LEU A 190
GLY A 177
ILE A 151
ILE A 173
 None
 0.81A 2q9rA-2r3uA:
undetectable		 2q9rA-2r3uA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rgw ASPARTATE
CARBAMOYLTRANSFERASE

(Methanocaldococcus
jannaschii) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A  43
GLY A  67
ILE A 300
ILE A  99
 None
 0.86A 2q9rA-2rgwA:
undetectable		 2q9rA-2rgwA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axs PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1

(Aquifex
aeolicus) 		PF02005
(TRM) 		4 LEU A  72
GLY A   7
ILE A  65
ILE A  68
 None
 0.77A 2q9rA-3axsA:
undetectable		 2q9rA-3axsA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxv SULFUR
OXYGENASE/REDUCTASE

(Acidianus
tengchongensis) 		PF07682
(SOR) 		4 LEU A  52
GLY A 164
ILE A 293
ILE A 292
 None
 0.74A 2q9rA-3bxvA:
undetectable		 2q9rA-3bxvA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d7l LIN1944 PROTEIN

(Listeria
innocua) 		PF13561
(adh_short_C2) 		4 LEU A  93
GLY A  88
ILE A  43
ILE A  46
 None
 0.81A 2q9rA-3d7lA:
undetectable		 2q9rA-3d7lA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebl GIBBERELLIN RECEPTOR
GID1

(Oryza sativa) 		PF07859
(Abhydrolase_3) 		4 LEU A 224
GLY A 201
ILE A 290
ILE A 291
 None
 0.79A 2q9rA-3eblA:
undetectable		 2q9rA-3eblA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcp L-ALA-D/L-GLU
EPIMERASE, A
MUCONATE LACTONIZING
ENZYME

(Klebsiella
pneumoniae) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  40
GLY A  50
ILE A  72
ILE A  10
 None
 0.74A 2q9rA-3fcpA:
undetectable		 2q9rA-3fcpA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fj4 MUCONATE
CYCLOISOMERASE

(Pseudomonas
protegens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  41
GLY A  51
ILE A  73
ILE A  11
 None
 0.83A 2q9rA-3fj4A:
undetectable		 2q9rA-3fj4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iom PURINE NUCLEOSIDE
PHOSPHORYLASE

(Mycobacterium
tuberculosis) 		PF01048
(PNP_UDP_1) 		4 LEU A 232
GLY A 122
ILE A 194
ILE A 236
 None
GNG  A 800 (-3.6A)
None
None
 0.75A 2q9rA-3iomA:
undetectable		 2q9rA-3iomA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcm U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP4

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 LEU B 261
GLY B 263
ILE B 268
ILE B 243
 None
 0.83A 2q9rA-3jcmB:
undetectable		 2q9rA-3jcmB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3js3 3-DEHYDROQUINATE
DEHYDRATASE

(Clostridioides
difficile) 		PF01487
(DHquinase_I) 		5 LEU A 224
GLY A  13
PRO A 200
ILE A 201
ILE A 202
 None
 1.37A 2q9rA-3js3A:
undetectable		 2q9rA-3js3A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgi PROTEASE DEGS

(Escherichia
coli) 		PF13365
(Trypsin_2) 		4 LEU A 190
GLY A 177
ILE A 151
ILE A 173
 None
 0.69A 2q9rA-3lgiA:
undetectable		 2q9rA-3lgiA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmd GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE

(Corynebacterium
glutamicum) 		PF00348
(polyprenyl_synt) 		4 LEU A 302
GLY A 307
ILE A 240
ILE A 243
 None
 0.66A 2q9rA-3lmdA:
1.8		 2q9rA-3lmdA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m21 PROBABLE TAUTOMERASE
HP_0924

(Helicobacter
pylori) 		PF01361
(Tautomerase) 		4 LEU A  22
GLY A  25
ILE A   3
ILE A   5
 None
 0.87A 2q9rA-3m21A:
undetectable		 2q9rA-3m21A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pu9 PROTEIN
SERINE/THREONINE
PHOSPHATASE

(Sphaerobacter
thermophilus) 		PF07228
(SpoIIE) 		4 LEU A 118
GLY A 181
ILE A 193
ILE A 157
 None
 0.80A 2q9rA-3pu9A:
undetectable		 2q9rA-3pu9A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q46 TT-IPPASE

(Thermococcus
thioreducens) 		PF00719
(Pyrophosphatase) 		4 GLY A  10
PRO A   9
ILE A 167
ILE A 163
 None
 0.87A 2q9rA-3q46A:
undetectable		 2q9rA-3q46A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3quv TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE

(Mycobacteroides
abscessus) 		PF01746
(tRNA_m1G_MT) 		4 GLY A 141
PRO A  83
ILE A 148
ILE A 133
 EDO  A 243 (-3.6A)
None
None
None
 0.84A 2q9rA-3quvA:
undetectable		 2q9rA-3quvA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6h ENOYL-COA HYDRATASE,
ECHA3

(Mycobacterium
marinum) 		PF00378
(ECH_1) 		4 LEU A  79
GLY A  82
ILE A 222
ILE A 225
 None
 0.80A 2q9rA-3r6hA:
undetectable		 2q9rA-3r6hA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5q NUCLEOPROTEIN

(Mopeia Lassa
virus
reassortant 29) 		PF00843
(Arena_nucleocap) 		4 LEU A 265
PRO A 318
ILE A 310
ILE A 306
 None
 0.81A 2q9rA-3t5qA:
undetectable		 2q9rA-3t5qA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ts3 CAPSID POLYPROTEIN

(Avastrovirus 3) 		PF16580
(Astro_capsid_p2) 		4 LEU A 578
PRO A 564
ILE A 539
ILE A 566
 None
 0.87A 2q9rA-3ts3A:
undetectable		 2q9rA-3ts3A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uvf INTRON-ENCODED DNA
ENDONUCLEASE I-HJEMI

(Trichoderma
reesei) 		PF00961
(LAGLIDADG_1) 		4 LEU A  53
GLY A  56
ILE A  46
ILE A  49
 None
 0.82A 2q9rA-3uvfA:
undetectable		 2q9rA-3uvfA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vse PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF10672
(Methyltrans_SAM) 		4 LEU A 314
GLY A 317
ILE A 290
ILE A 292
 None
 0.74A 2q9rA-3vseA:
undetectable		 2q9rA-3vseA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w3s TYPE-2 SERINE--TRNA
LIGASE

(Methanopyrus
kandleri) 		PF00587
(tRNA-synt_2b) 		4 LEU A  11
GLY A  95
ILE A  22
ILE A  61
 None
C  B  56 ( 3.2A)
None
None
 0.83A 2q9rA-3w3sA:
undetectable		 2q9rA-3w3sA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhn PA_0080

(Pseudomonas
aeruginosa) 		PF12790
(T6SS-SciN) 		4 LEU A 111
GLY A  94
ILE A 130
ILE A 132
 None
 0.85A 2q9rA-3zhnA:
undetectable		 2q9rA-3zhnA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4anf ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC

(Mycoplasma
penetrans) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A  10
GLY A 131
ILE A 332
ILE A 335
 None
 0.64A 2q9rA-4anfA:
undetectable		 2q9rA-4anfA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzk PROTEIN TRANSPORT
PROTEIN SEC31

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12931
(Sec16_C) 		5 LEU A 252
GLY A 255
PRO A 235
ILE A 260
ILE A 237
 None
 1.15A 2q9rA-4bzkA:
undetectable		 2q9rA-4bzkA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fp9 MTERF
DOMAIN-CONTAINING
PROTEIN 2

(Homo sapiens) 		PF02536
(mTERF) 		5 LEU B  99
GLY B 103
PRO B 138
ILE B 132
ILE B 128
 None
 1.42A 2q9rA-4fp9B:
undetectable		 2q9rA-4fp9B:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g6u EC869 CDII

(Escherichia
coli) 		PF07262
(CdiI) 		4 LEU B 158
GLY B  52
ILE B 119
ILE B 121
 None
 0.83A 2q9rA-4g6uB:
undetectable		 2q9rA-4g6uB:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdj NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 LEU A 303
GLY A 291
PRO A 301
ILE A 273
 None
None
None
FUC  A 503 ( 4.2A)
 0.84A 2q9rA-4gdjA:
undetectable		 2q9rA-4gdjA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grs PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE,
2-DEHYDRO-3-DEOXYPHO
SPHOHEPTONATE
ALDOLASE

(Pyrococcus
furiosus;
Thermotoga
maritima) 		PF00793
(DAHP_synth_1) 		4 LEU A 205
PRO A 203
ILE A  83
ILE A 233
 None
 0.84A 2q9rA-4grsA:
undetectable		 2q9rA-4grsA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4je3 CENTRAL KINETOCHORE
SUBUNIT CHL4

(Saccharomyces
cerevisiae) 		PF05238
(CENP-N) 		4 LEU B 413
GLY B 433
ILE B 382
ILE B 409
 None
 0.86A 2q9rA-4je3B:
undetectable		 2q9rA-4je3B:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgv NUCLEAR RECEPTOR
SUBFAMILY 4 GROUP A
MEMBER 1

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 410
GLY A 412
ILE A 587
ILE A 588
 None
 0.86A 2q9rA-4jgvA:
undetectable		 2q9rA-4jgvA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

([Candida]
glabrata) 		PF00885
(DMRL_synthase) 		4 LEU A  35
GLY A  38
ILE A  22
ILE A  88
 None
 0.85A 2q9rA-4kq6A:
undetectable		 2q9rA-4kq6A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7s BTRN

(Bacillus
circulans) 		PF13186
(SPASM) 		4 LEU A  44
GLY A 182
ILE A 208
ILE A 205
 None
 0.71A 2q9rA-4m7sA:
undetectable		 2q9rA-4m7sA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsx U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN 21

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 LEU A 581
GLY A 583
ILE A 588
ILE A 567
 None
 0.87A 2q9rA-4nsxA:
undetectable		 2q9rA-4nsxA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2

(Mus musculus) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 LEU A 535
GLY A 228
ILE A 338
ILE A 342
 EDO  A 616 ( 4.4A)
EDO  A 616 ( 4.5A)
None
None
 0.82A 2q9rA-4ph9A:
undetectable		 2q9rA-4ph9A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pke PROTEIN C10C5.1,
ISOFORM I

(Caenorhabditis
elegans) 		PF12166
(Piezo_RRas_bdg) 		4 GLY A 250
PRO A 249
ILE A 201
ILE A 202
 None
 0.81A 2q9rA-4pkeA:
undetectable		 2q9rA-4pkeA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q82 PHOSPHOLIPASE/CARBOX
YLESTERASE

(Haliangium
ochraceum) 		no annotation 4 LEU A 204
GLY A 209
PRO A 244
ILE A 225
 None
 0.80A 2q9rA-4q82A:
undetectable		 2q9rA-4q82A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rn7 N-ACETYLMURAMOYL-L-A
LANINE AMIDASE

(Clostridioides
difficile) 		PF01520
(Amidase_3) 		4 LEU A 223
GLY A 290
ILE A 260
ILE A 258
 None
 0.74A 2q9rA-4rn7A:
undetectable		 2q9rA-4rn7A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG

(Escherichia
coli) 		PF03783
(CsgG) 		4 LEU A 172
GLY A 231
ILE A  34
ILE A 121
 None
 0.84A 2q9rA-4uv2A:
undetectable		 2q9rA-4uv2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9e DEOXYGUANOSINETRIPHO
SPHATE
TRIPHOSPHOHYDROLASE

(Escherichia
coli) 		PF01966
(HD) 		4 GLY A 487
PRO A 123
ILE A 407
ILE A 132
 None
 0.85A 2q9rA-4x9eA:
1.4		 2q9rA-4x9eA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zb8 PCURE2P6

(Phanerochaete
chrysosporium) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 GLY A  18
PRO A  59
ILE A  77
ILE A  78
 None
GDS  A 300 (-4.4A)
None
None
 0.84A 2q9rA-4zb8A:
undetectable		 2q9rA-4zb8A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqu CDII TOXIN

(Salmonella
enterica) 		PF07262
(CdiI) 		4 LEU B 168
GLY B  51
ILE B 129
ILE B 131
 None
 0.82A 2q9rA-4zquB:
undetectable		 2q9rA-4zquB:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqv CDII IMMUNITY
PROTEIN

(Yersinia
kristensenii) 		PF07262
(CdiI) 		4 LEU A 156
GLY A  51
ILE A 117
ILE A 119
 None
 0.74A 2q9rA-4zqvA:
undetectable		 2q9rA-4zqvA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6f GATING RING OF
POTASSIUM CHANNEL
SUBFAMILY T MEMBER 1

(Gallus gallus) 		PF03493
(BK_channel_a) 		4 LEU C 587
GLY C 576
ILE C1009
ILE C1165
 None
 0.69A 2q9rA-5a6fC:
undetectable		 2q9rA-5a6fC:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b69 GERANYLGERANYLGLYCER
YL PHOSPHATE
SYNTHASE

(Thermoplasma
acidophilum) 		PF01884
(PcrB) 		4 LEU A  83
PRO A  79
ILE A  92
ILE A  85
 None
 0.85A 2q9rA-5b69A:
undetectable		 2q9rA-5b69A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cvo WD REPEAT-CONTAINING
PROTEIN 48

(Homo sapiens) 		PF00400
(WD40) 		4 LEU A 164
GLY A 166
ILE A 171
ILE A 141
 None
 0.84A 2q9rA-5cvoA:
undetectable		 2q9rA-5cvoA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2e BETA-LACTAMASE

(Yersinia
enterocolitica) 		PF13354
(Beta-lactamase2) 		4 GLY A 231
PRO A 228
ILE A 234
ILE A 265
 None
 0.77A 2q9rA-5e2eA:
undetectable		 2q9rA-5e2eA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqi SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 1

(Homo sapiens) 		PF00083
(Sugar_tr) 		4 LEU A 188
GLY A 111
ILE A 193
ILE A 192
 None
 0.73A 2q9rA-5eqiA:
undetectable		 2q9rA-5eqiA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsg PUTATIVE ABC
TRANSPORTER,
NUCLEOTIDE
BINDING/ATPASE
PROTEIN

(Klebsiella
pneumoniae) 		PF13407
(Peripla_BP_4) 		5 LEU A  93
GLY A  91
PRO A 115
ILE A 287
ILE A 117
 None
 1.24A 2q9rA-5hsgA:
undetectable		 2q9rA-5hsgA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2

(Homo sapiens) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 LEU A 534
GLY A 227
ILE A 337
ILE A 341
 None
 0.80A 2q9rA-5ikrA:
undetectable		 2q9rA-5ikrA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im4 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Candida
albicans) 		PF00885
(DMRL_synthase) 		4 LEU A  35
GLY A  38
ILE A  22
ILE A  88
 None
 0.82A 2q9rA-5im4A:
undetectable		 2q9rA-5im4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jd8 PERIPLASMIC SERINE
PEPTIDASE DEGS

(Yersinia pestis) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 LEU A 189
GLY A 176
ILE A 150
ILE A 172
 None
 0.69A 2q9rA-5jd8A:
undetectable		 2q9rA-5jd8A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mxp -

(-) 		no annotation 4 LEU A  35
GLY A 111
ILE A 122
ILE A  99
 None
 0.74A 2q9rA-5mxpA:
undetectable		 2q9rA-5mxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncc FATTY ACID
PHOTODECARBOXYLASE

(Chlorella
variabilis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		5 LEU A 516
GLY A 514
PRO A 513
ILE A 155
ILE A 571
 None
 1.34A 2q9rA-5nccA:
undetectable		 2q9rA-5nccA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8z CAROTENOID OXYGENASE
1

(Neurospora
crassa) 		PF03055
(RPE65) 		4 LEU A 239
GLY A 289
ILE A 247
ILE A 222
 None
 0.84A 2q9rA-5u8zA:
undetectable		 2q9rA-5u8zA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usf TYROSYL-TRNA
SYNTHETASE, PUTATIVE

(Leishmania
donovani) 		PF00579
(tRNA-synt_1b) 		4 LEU A 492
GLY A 496
ILE A 142
ILE A 139
 None
 0.84A 2q9rA-5usfA:
undetectable		 2q9rA-5usfA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v07 EXONUCLEASE 1

(Homo sapiens) 		PF00752
(XPG_N)
PF00867
(XPG_I) 		4 LEU Z  35
GLY Z  38
ILE Z 123
ILE Z 125
 None
 0.83A 2q9rA-5v07Z:
undetectable		 2q9rA-5v07Z:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wuj FLAGELLAR MOTOR
SWITCH PROTEIN FLIG

(Helicobacter
pylori) 		no annotation 4 LEU B  26
GLY B  35
ILE B  46
ILE B  49
 None
 0.77A 2q9rA-5wujB:
undetectable		 2q9rA-5wujB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Mycolicibacterium
smegmatis) 		no annotation 5 LEU A 171
GLY A 169
PRO A 142
ILE A 163
ILE A 174
 None
 1.43A 2q9rA-6fv4A:
undetectable		 2q9rA-6fv4A:
undetectable