SIMILAR PATTERNS OF AMINO ACIDS FOR 2Q8H_A_TF4A438_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b4a ARGININE REPRESSOR

(Geobacillus
stearothermophilus) 		PF01316
(Arg_repressor)
PF02863
(Arg_repressor_C) 		4 LEU A  25
ILE A  45
ARG A   6
ILE A  10
 None
 1.01A 2q8hA-1b4aA:
undetectable		 2q8hA-1b4aA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)

(Lactobacillus
sp. 30A) 		PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C) 		4 LEU A 217
ILE A 254
ILE A 306
ARG A 305
 None
 0.94A 2q8hA-1c4kA:
0.0		 2q8hA-1c4kA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dk5 ANNEXIN 24(CA32)

(Capsicum annuum) 		PF00191
(Annexin) 		4 LEU A 183
TYR A 216
ILE A 242
ILE A 187
 None
 1.00A 2q8hA-1dk5A:
0.0		 2q8hA-1dk5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dq3 ENDONUCLEASE

(Pyrococcus
furiosus) 		PF09061
(Stirrup)
PF09062
(Endonuc_subdom)
PF14528
(LAGLIDADG_3)
PF14890
(Intein_splicing) 		4 LEU A 186
TYR A 194
ILE A 171
ILE A 212
 None
 0.88A 2q8hA-1dq3A:
0.0		 2q8hA-1dq3A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ek6 UDP-GALACTOSE
4-EPIMERASE

(Homo sapiens) 		PF16363
(GDP_Man_Dehyd) 		4 LEU A  22
TYR A  27
ILE A  86
ILE A 252
 None
TMA  A 952 ( 3.6A)
None
None
 0.99A 2q8hA-1ek6A:
undetectable		 2q8hA-1ek6A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ev1 ECHOVIRUS 1

(Enterovirus B) 		PF00073
(Rhv) 		4 LEU 1 219
TYR 1 146
ILE 1 119
ILE 1  95
 None
PLM  1   0 (-3.7A)
None
PLM  1   0 ( 4.6A)
 0.70A 2q8hA-1ev11:
undetectable		 2q8hA-1ev11:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fvf SEC1

(Doryteuthis
pealeii) 		PF00995
(Sec1) 		4 TYR A 400
ILE A 430
ARG A 586
ILE A 437
 None
 0.87A 2q8hA-1fvfA:
0.0		 2q8hA-1fvfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7o 4-HYDROXYPHENYLACETA
TE DEGRADATION
BIFUNCTIONAL
ISOMERASE/DECARBOXYL
ASE

(Escherichia
coli) 		PF01557
(FAA_hydrolase) 		4 LEU A 330
TYR A 308
ILE A 310
ARG A 266
 None
 0.97A 2q8hA-1i7oA:
undetectable		 2q8hA-1i7oA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0a 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
DEAMINASE

(Pyrococcus
horikoshii) 		PF00291
(PALP) 		4 LEU A 198
TYR A 167
ILE A 174
ILE A 306
 None
 0.82A 2q8hA-1j0aA:
0.0		 2q8hA-1j0aA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgd PERIPHERAL PLASMA
MEMBRANE CASK

(Homo sapiens) 		PF00625
(Guanylate_kin) 		4 LEU A 901
ILE A 829
ARG A 747
ILE A 750
 None
 0.96A 2q8hA-1kgdA:
undetectable		 2q8hA-1kgdA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ko7 HPR
KINASE/PHOSPHATASE

(Staphylococcus
xylosus) 		PF02603
(Hpr_kinase_N)
PF07475
(Hpr_kinase_C) 		4 LEU A 121
ILE A  85
ARG A  33
ILE A  31
 None
None
PO4  A 315 (-2.8A)
None
 0.98A 2q8hA-1ko7A:
undetectable		 2q8hA-1ko7A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9i ANNEXIN VI

(Homo sapiens) 		PF00191
(Annexin) 		4 LEU A 203
ILE A 226
ILE A 249
ARG A 250
 None
 0.92A 2q8hA-1m9iA:
undetectable		 2q8hA-1m9iA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v2b 23-KDA POLYPEPTIDE
OF PHOTOSYSTEM II
OXYGEN-EVOLVING
COMPLEX

(Nicotiana
tabacum) 		PF01789
(PsbP) 		4 LEU A  87
TYR A  86
ILE A  60
ILE A 158
 None
 0.88A 2q8hA-1v2bA:
undetectable		 2q8hA-1v2bA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1whs SERINE
CARBOXYPEPTIDASE II

(Triticum
aestivum) 		PF00450
(Peptidase_S10) 		4 LEU A 123
TYR A 120
ILE A 142
ILE A 167
 None
 0.88A 2q8hA-1whsA:
undetectable		 2q8hA-1whsA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x94 PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE

(Vibrio cholerae) 		PF13580
(SIS_2) 		4 LEU A  66
TYR A  70
ILE A  37
ILE A 183
 None
 1.00A 2q8hA-1x94A:
undetectable		 2q8hA-1x94A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xxi DNA POLYMERASE III
SUBUNIT GAMMA

(Escherichia
coli) 		PF12169
(DNA_pol3_gamma3)
PF13177
(DNA_pol3_delta2) 		4 LEU B 281
ILE B 268
ARG B 274
ILE B 276
 None
 0.99A 2q8hA-1xxiB:
undetectable		 2q8hA-1xxiB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z45 GAL10 BIFUNCTIONAL
PROTEIN

(Saccharomyces
cerevisiae) 		PF01263
(Aldose_epim)
PF16363
(GDP_Man_Dehyd) 		4 LEU A  31
TYR A  36
ILE A  89
ILE A 259
 None
 0.98A 2q8hA-1z45A:
undetectable		 2q8hA-1z45A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zsw GLYOXALASE FAMILY
PROTEIN

(Bacillus cereus) 		PF00903
(Glyoxalase) 		4 LEU A  60
TYR A  24
ILE A 154
ILE A  81
 None
 0.96A 2q8hA-1zswA:
undetectable		 2q8hA-1zswA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bu2 PYRUVATE
DEHYDROGENSAE KINASE
ISOENZYME 2

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 LEU A  53
ILE A 111
ARG A 158
ILE A 157
 None
 0.89A 2q8hA-2bu2A:
46.6		 2q8hA-2bu2A:
68.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bu2 PYRUVATE
DEHYDROGENSAE KINASE
ISOENZYME 2

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		5 LEU A  53
TYR A  80
ARG A 154
ILE A 157
ARG A 158
 None
 0.84A 2q8hA-2bu2A:
46.6		 2q8hA-2bu2A:
68.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bu2 PYRUVATE
DEHYDROGENSAE KINASE
ISOENZYME 2

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		5 LEU A  53
TYR A  80
ILE A 111
ARG A 154
ILE A 157
 None
 0.57A 2q8hA-2bu2A:
46.6		 2q8hA-2bu2A:
68.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d13 HYPOTHETICAL PROTEIN
PH1257

(Pyrococcus
horikoshii) 		PF01902
(Diphthami_syn_2) 		4 LEU A  25
ILE A  64
ARG A  30
ARG A  32
 None
 0.89A 2q8hA-2d13A:
undetectable		 2q8hA-2d13A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE

(Clostridium
acetobutylicum) 		PF08942
(DUF1919) 		4 LEU A  20
TYR A  13
ILE A  64
ILE A  31
 None
 0.90A 2q8hA-2g6tA:
undetectable		 2q8hA-2g6tA:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hiy HYPOTHETICAL PROTEIN

(Streptococcus
pneumoniae) 		PF08002
(DUF1697) 		4 LEU A 154
TYR A 150
ILE A 135
ILE A 165
 GOL  A8002 ( 4.5A)
None
None
None
 0.96A 2q8hA-2hiyA:
undetectable		 2q8hA-2hiyA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nrk HYPOTHETICAL PROTEIN
GRPB

(Enterococcus
faecalis) 		PF04229
(GrpB) 		4 LEU A  89
TYR A  77
ILE A  26
ILE A 102
 None
 0.95A 2q8hA-2nrkA:
undetectable		 2q8hA-2nrkA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz0 POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY D
MEMBER 3

(Homo sapiens) 		PF02214
(BTB_2)
PF11601
(Shal-type) 		4 LEU B  44
TYR B  82
ILE B  42
ARG B  55
 None
 0.96A 2q8hA-2nz0B:
undetectable		 2q8hA-2nz0B:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2olt HYPOTHETICAL PROTEIN

(Shewanella
oneidensis) 		PF01865
(PhoU_div) 		4 LEU A 179
TYR A 124
ILE A 113
ILE A 202
 None
 0.95A 2q8hA-2oltA:
2.2		 2q8hA-2oltA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prz OROTATE
PHOSPHORIBOSYLTRANSF
ERASE 1

(Saccharomyces
cerevisiae) 		PF00156
(Pribosyltran) 		4 LEU A  21
TYR A  36
ILE A 206
ILE A 198
 None
 0.93A 2q8hA-2przA:
undetectable		 2q8hA-2przA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qdl CHEMOTAXIS SIGNAL
TRANSDUCTION PROTEIN

(Caldanaerobacter
subterraneus) 		PF01584
(CheW) 		4 LEU A  95
ILE A  88
ARG A  69
ILE A  64
 None
 0.80A 2q8hA-2qdlA:
undetectable		 2q8hA-2qdlA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvl DIACYLGLYCEROL
KINASE DGKB

(Staphylococcus
aureus) 		PF00781
(DAGK_cat) 		4 LEU A 221
TYR A 182
ILE A 260
ILE A 223
 None
 0.82A 2q8hA-2qvlA:
undetectable		 2q8hA-2qvlA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r2p EPHRIN TYPE-A
RECEPTOR 5

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM) 		4 LEU A 791
ILE A 727
ARG A 799
ARG A 823
 None
None
SO4  A   1 ( 3.1A)
SO4  A   1 ( 3.9A)
 0.94A 2q8hA-2r2pA:
undetectable		 2q8hA-2r2pA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrk ALPHA-L-ARABINOFURAN
OSIDASE

(Thermobacillus
xylanilyticus) 		PF06964
(Alpha-L-AF_C) 		4 LEU A 116
ILE A  34
ARG A  53
ILE A  52
 None
 1.00A 2q8hA-2vrkA:
undetectable		 2q8hA-2vrkA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xcm CYTOSOLIC HEAT SHOCK
PROTEIN 90

(Hordeum vulgare) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 LEU A 131
TYR A  26
ILE A 119
ILE A  21
 None
 0.88A 2q8hA-2xcmA:
5.3		 2q8hA-2xcmA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xi7 RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF15518
(L_protein_N) 		4 LEU A  88
TYR A  83
ILE A  59
ILE A 122
 None
 1.00A 2q8hA-2xi7A:
undetectable		 2q8hA-2xi7A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahx BETA-GLUCOSIDASE A

(Clostridium
cellulovorans) 		PF00232
(Glyco_hydro_1) 		4 LEU A 150
TYR A 146
ILE A  98
ILE A  80
 None
 0.89A 2q8hA-3ahxA:
undetectable		 2q8hA-3ahxA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c19 UNCHARACTERIZED
PROTEIN MK0293

(Methanopyrus
kandleri) 		PF01969
(DUF111) 		4 LEU A 168
TYR A 109
ILE A 141
ILE A 147
 None
 0.87A 2q8hA-3c19A:
undetectable		 2q8hA-3c19A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e82 PUTATIVE
OXIDOREDUCTASE

(Klebsiella
pneumoniae) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 LEU A  78
ILE A  35
ARG A 315
ILE A  16
 None
 0.91A 2q8hA-3e82A:
undetectable		 2q8hA-3e82A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed5 YFNB

(Bacillus
subtilis) 		PF13419
(HAD_2) 		4 LEU A 227
TYR A   4
ILE A 179
ILE A 226
 None
 0.87A 2q8hA-3ed5A:
undetectable		 2q8hA-3ed5A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez6 PLASMID PARTITION
PROTEIN A

(Escherichia
coli) 		PF13614
(AAA_31) 		4 LEU A 241
TYR A 245
ILE A 149
ILE A 192
 None
 0.93A 2q8hA-3ez6A:
undetectable		 2q8hA-3ez6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD

(Bacillus
anthracis) 		no annotation 4 LEU S 451
TYR S 444
ILE S 425
ILE S 504
 None
 0.94A 2q8hA-3g9kS:
undetectable		 2q8hA-3g9kS:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gov MASP-1

(Homo sapiens) 		PF00084
(Sushi) 		4 LEU A 304
TYR A 319
ILE A 347
ILE A 312
 None
 0.80A 2q8hA-3govA:
undetectable		 2q8hA-3govA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ia8 THAP
DOMAIN-CONTAINING
PROTEIN 4

(Homo sapiens) 		PF08768
(DUF1794) 		4 LEU A 106
ILE A  74
ARG A 129
ILE A 108
 None
None
HEM  A   1 (-3.5A)
None
 0.95A 2q8hA-3ia8A:
undetectable		 2q8hA-3ia8A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iy7 FRAGMENT FROM
NEUTRALIZING
ANTIBODY F (LIGHT
CHAIN)

(Rattus
norvegicus) 		PF07686
(V-set) 		5 LEU A  71
TYR A  84
ILE A  56
ILE A  73
ARG A  59
 None
 1.22A 2q8hA-3iy7A:
undetectable		 2q8hA-3iy7A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2z LEXA REPRESSOR

(Thermotoga
maritima) 		PF00717
(Peptidase_S24)
PF01726
(LexA_DNA_bind) 		4 LEU A  12
TYR A  54
ILE A  67
ILE A  71
 None
 0.91A 2q8hA-3k2zA:
undetectable		 2q8hA-3k2zA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kol GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Nostoc
punctiforme) 		PF00903
(Glyoxalase) 		4 LEU A  41
TYR A  37
ILE A 121
ILE A 146
 None
 0.99A 2q8hA-3kolA:
undetectable		 2q8hA-3kolA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksy SON OF SEVENLESS
HOMOLOG 1

(Homo sapiens) 		PF00125
(Histone)
PF00169
(PH)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF00621
(RhoGEF) 		5 LEU A 343
TYR A 298
ILE A 245
ILE A 222
ARG A 227
 None
 1.40A 2q8hA-3ksyA:
4.7		 2q8hA-3ksyA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kux PUTATIVE
OXIDOREDUCTASE

(Yersinia pestis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 LEU A  67
ILE A  24
ARG A 307
ILE A   5
 None
 0.92A 2q8hA-3kuxA:
undetectable		 2q8hA-3kuxA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwt PHOSPHOINOSITIDE
PHOSPHATASE SAC1

(Saccharomyces
cerevisiae) 		PF02383
(Syja_N) 		4 LEU X  64
TYR X 111
ILE X  95
ILE X  62
 None
 1.00A 2q8hA-3lwtX:
undetectable		 2q8hA-3lwtX:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 251
TYR A 246
ILE A 326
ILE A 256
 None
 0.97A 2q8hA-3my0A:
undetectable		 2q8hA-3my0A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nxs LAO/AO TRANSPORT
SYSTEM ATPASE

(Mycolicibacterium
smegmatis) 		PF03308
(ArgK) 		4 LEU A  22
TYR A 118
ARG A 120
ILE A  26
 None
 0.79A 2q8hA-3nxsA:
undetectable		 2q8hA-3nxsA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqn CONSERVED DOMAIN
PROTEIN

(Enterococcus
faecalis) 		PF05043
(Mga) 		4 LEU A  20
ILE A  70
ILE A  53
ARG A  54
 None
 0.81A 2q8hA-3sqnA:
undetectable		 2q8hA-3sqnA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uo7 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE

(Homo sapiens) 		PF03167
(UDG) 		4 LEU A 292
ILE A 187
ARG A 225
ILE A 226
 None
 0.83A 2q8hA-3uo7A:
undetectable		 2q8hA-3uo7A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiq KOJIBIOSE
PHOSPHORYLASE

(Caldicellulosiruptor
saccharolyticus) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 LEU A 606
TYR A 493
ILE A 637
ILE A 347
 None
 0.91A 2q8hA-3wiqA:
undetectable		 2q8hA-3wiqA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wtr UNCHARACTERIZED
PROTEIN

(Escherichia
coli) 		PF04315
(EpmC) 		4 LEU A 161
TYR A 165
ILE A  58
ILE A  13
 None
 0.94A 2q8hA-3wtrA:
undetectable		 2q8hA-3wtrA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aqb MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Homo sapiens) 		PF00084
(Sushi)
PF00431
(CUB)
PF14670
(FXa_inhibition) 		4 LEU A 304
TYR A 319
ILE A 347
ILE A 312
 None
 0.78A 2q8hA-4aqbA:
undetectable		 2q8hA-4aqbA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c02 ACTIVIN RECEPTOR
TYPE-1

(Homo sapiens) 		PF00069
(Pkinase)
PF08515
(TGF_beta_GS) 		4 LEU A 257
TYR A 252
ILE A 332
ILE A 262
 None
 0.84A 2q8hA-4c02A:
undetectable		 2q8hA-4c02A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fg8 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 211
ILE A 158
ILE A 107
ARG A 106
 None
 0.99A 2q8hA-4fg8A:
undetectable		 2q8hA-4fg8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gqt HEAT SHOCK PROTEIN
90

(Caenorhabditis
elegans) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 LEU A 131
TYR A  26
ILE A 119
ILE A  21
 None
 0.85A 2q8hA-4gqtA:
5.3		 2q8hA-4gqtA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gsl AUTOPHAGY-RELATED
PROTEIN 3

(Saccharomyces
cerevisiae) 		PF03986
(Autophagy_N)
PF03987
(Autophagy_act_C)
PF10381
(Autophagy_C) 		4 LEU C 291
TYR C 305
ILE C 173
ILE C 294
 None
 0.91A 2q8hA-4gslC:
undetectable		 2q8hA-4gslC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1g MALTOSE BINDING
PROTEIN-CAKAR3 MOTOR
DOMAIN FUSION
PROTEIN

(Candida
albicans;
Escherichia
coli) 		PF00225
(Kinesin)
PF13416
(SBP_bac_8) 		4 LEU A 389
TYR A 375
ILE A 660
ILE A 409
 None
 0.97A 2q8hA-4h1gA:
undetectable		 2q8hA-4h1gA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjj ANTI-IL12 ANTI-IL18
DFAB LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		5 LEU L 186
TYR L 199
ILE L 171
ILE L 188
ARG L 174
 None
 1.33A 2q8hA-4hjjL:
undetectable		 2q8hA-4hjjL:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igd MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		4 LEU A 304
TYR A 319
ILE A 347
ILE A 312
 None
 0.86A 2q8hA-4igdA:
undetectable		 2q8hA-4igdA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ina SACCHAROPINE
DEHYDROGENASE

(Wolinella
succinogenes) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 LEU A 234
ILE A 167
ARG A 248
ILE A 247
 None
 0.95A 2q8hA-4inaA:
undetectable		 2q8hA-4inaA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxj RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A

(Rickettsia
bellii) 		PF00398
(RrnaAD) 		4 LEU A 264
TYR A 261
ILE A 247
ILE A 227
 None
 0.93A 2q8hA-4jxjA:
undetectable		 2q8hA-4jxjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7k CATION EFFLUX SYSTEM
PROTEIN CUSC

(Escherichia
coli) 		PF02321
(OEP) 		4 LEU A 273
TYR A 349
ILE A 325
ILE A 280
 None
 0.90A 2q8hA-4k7kA:
3.7		 2q8hA-4k7kA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lj2 CHORISMATE SYNTHASE

(Acinetobacter
baumannii) 		PF01264
(Chorismate_synt) 		4 LEU A 336
ILE A 286
ARG A 154
ILE A 153
 None
 0.95A 2q8hA-4lj2A:
undetectable		 2q8hA-4lj2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8n PLEXINC1
INTRACELLULAR REGION

(Danio rerio) 		PF08337
(Plexin_cytopl) 		4 LEU A 675
ILE A 689
ILE A 644
ARG A 645
 None
 0.90A 2q8hA-4m8nA:
undetectable		 2q8hA-4m8nA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qjy GH127
BETA-L-ARABINOFURANO
SIDASE

(Geobacillus
stearothermophilus) 		PF07944
(Glyco_hydro_127) 		4 LEU A 192
TYR A 204
ILE A 168
ILE A 142
 None
 0.97A 2q8hA-4qjyA:
undetectable		 2q8hA-4qjyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9g MBP1

(Caldanaerobius
polysaccharolyticus) 		PF13416
(SBP_bac_8) 		4 LEU A 103
TYR A 106
ILE A 325
ILE A 311
 None
 0.92A 2q8hA-4r9gA:
undetectable		 2q8hA-4r9gA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ro1 DIS3-LIKE
EXONUCLEASE 2

(Schizosaccharomyces
pombe) 		no annotation 4 LEU B 514
ILE B 775
ARG B 770
ILE B 769
 None
 0.80A 2q8hA-4ro1B:
undetectable		 2q8hA-4ro1B:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3j CORTICAL-LYTIC
ENZYME

(Bacillus cereus) 		PF00704
(Glyco_hydro_18)
PF01476
(LysM) 		4 LEU A 110
TYR A 137
ILE A 160
ILE A 117
 None
 0.97A 2q8hA-4s3jA:
undetectable		 2q8hA-4s3jA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqg DNA POLYMERASE

(Geobacillus
stearothermophilus) 		PF00476
(DNA_pol_A) 		4 LEU A 662
TYR A 749
ILE A 712
ILE A 796
 None
 0.99A 2q8hA-4uqgA:
undetectable		 2q8hA-4uqgA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1u LYND

(Lyngbya
aestuarii) 		PF02624
(YcaO) 		4 LEU A 358
TYR A 355
ILE A 306
ILE A 725
 None
 0.97A 2q8hA-4v1uA:
undetectable		 2q8hA-4v1uA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4p UBIQUITIN-CONJUGATIN
G ENZYME E2 Z

(Homo sapiens) 		PF00179
(UQ_con) 		4 LEU A 313
TYR A 310
ARG A 245
ILE A 249
 PEG  A1332 (-4.9A)
None
None
None
 0.97A 2q8hA-5a4pA:
undetectable		 2q8hA-5a4pA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9i SOLUTE CARRIER
FAMILY 15 MEMBER 2

(Rattus
norvegicus) 		no annotation 5 LEU A 572
TYR A 556
ILE A 529
ILE A 517
ARG A 549
 None
 0.87A 2q8hA-5a9iA:
undetectable		 2q8hA-5a9iA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amq RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF04196
(Bunya_RdRp)
PF15518
(L_protein_N) 		4 LEU A  88
TYR A  83
ILE A  59
ILE A 122
 None
 0.95A 2q8hA-5amqA:
undetectable		 2q8hA-5amqA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cju ISOBUTYRYL-COA
MUTASE FUSED

(Cupriavidus
metallidurans) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding)
PF03308
(ArgK) 		4 LEU A 161
TYR A 164
ILE A 109
ILE A 159
 None
 1.00A 2q8hA-5cjuA:
undetectable		 2q8hA-5cjuA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eor ANTI VACCINIA VIRUS
A27 ANTIBODY 8E3
LIGHT CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L  78
TYR L  91
ILE L  63
ILE L  80
 None
 0.97A 2q8hA-5eorL:
undetectable		 2q8hA-5eorL:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fb3 GLYCEROL-1-PHOSPHATE
DEHYDROGENASE
[NAD(P)+]

(Pyrobaculum
calidifontis) 		PF13685
(Fe-ADH_2) 		4 TYR A 191
ILE A 273
ILE A 278
ARG A 277
 None
 0.99A 2q8hA-5fb3A:
undetectable		 2q8hA-5fb3A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl7 ATP SYNTHASE SUBUNIT
BETA

(Yarrowia
lipolytica) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		5 LEU D 248
ILE D 238
ARG D 125
ILE D 126
ARG D 137
 None
 1.49A 2q8hA-5fl7D:
undetectable		 2q8hA-5fl7D:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g53 ADENOSINE RECEPTOR
A2A
ENGINEERED DOMAIN OF
HUMAN G ALPHA S LONG
ISOFORM

(Homo sapiens) 		PF00001
(7tm_1)
PF00503
(G-alpha) 		4 LEU C 393
TYR C 391
ILE A 238
ILE A 200
 None
 1.01A 2q8hA-5g53C:
undetectable		 2q8hA-5g53C:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR

(Homo sapiens) 		PF16647
(GCSF) 		4 LEU A  36
TYR A  40
ILE A  96
ARG A 147
 None
 0.94A 2q8hA-5gw9A:
undetectable		 2q8hA-5gw9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		4 LEU A 849
TYR A 846
ILE A 854
ARG A 861
 None
 0.98A 2q8hA-5gzuA:
undetectable		 2q8hA-5gzuA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4a ARGONAUTE PROTEIN

(Marinitoga
piezophila) 		no annotation 4 LEU A   5
TYR A 254
ILE A 567
ILE A 137
 None
 1.00A 2q8hA-5i4aA:
undetectable		 2q8hA-5i4aA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lx8 SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 LEU A 550
TYR A  69
ILE A  98
ILE A 105
 None
 0.99A 2q8hA-5lx8A:
undetectable		 2q8hA-5lx8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oac MAJOR CAPSID PROTEIN

(unidentified
phage) 		no annotation 4 LEU A 212
ILE A 254
ARG A 279
ILE A 191
 None
 0.60A 2q8hA-5oacA:
undetectable		 2q8hA-5oacA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Eremothecium
gossypii) 		PF00478
(IMPDH)
PF00571
(CBS) 		4 LEU A  61
ILE A  96
ILE A 365
ARG A 325
 None
None
None
5GP  A 600 (-3.1A)
 0.98A 2q8hA-5tc3A:
undetectable		 2q8hA-5tc3A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT

(Gracilaria
chilensis) 		PF00502
(Phycobilisome) 		4 LEU A 141
ILE A  96
ARG A  38
ILE A  42
 None
 0.96A 2q8hA-5tjfA:
undetectable		 2q8hA-5tjfA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wc8 SIAD

(Mannheimia
haemolytica) 		no annotation 4 LEU M 335
ILE M 401
ARG M 332
ILE M 253
 None
None
BR  M 509 (-3.3A)
None
 0.85A 2q8hA-5wc8M:
undetectable		 2q8hA-5wc8M:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgv PYRE3

(Streptomyces
rugosporus) 		no annotation 4 LEU A 104
ILE A 292
ARG A  57
ILE A  59
 None
 0.60A 2q8hA-5xgvA:
undetectable		 2q8hA-5xgvA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
US2

(Toxoplasma
gondii) 		PF00318
(Ribosomal_S2) 		4 LEU A 179
TYR A 176
ILE A 162
ILE A 124
 None
 0.95A 2q8hA-5xxuA:
undetectable		 2q8hA-5xxuA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y10 MEMBRANE
GLYCOPROTEIN
POLYPROTEIN

(SFTS
phlebovirus) 		PF07243
(Phlebovirus_G1) 		4 LEU C 173
TYR C 124
ILE C 175
ARG C 332
 None
 0.72A 2q8hA-5y10C:
undetectable		 2q8hA-5y10C:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ynl ARGINASE

(Glaciozyma
antarctica) 		no annotation 4 LEU A 201
TYR A 187
ILE A 193
ILE A 140
 None
 0.81A 2q8hA-5ynlA:
undetectable		 2q8hA-5ynlA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccz SERINE
HYDROXYMETHYLTRANSFE
RASE

(Medicago
truncatula) 		no annotation 4 LEU A 258
TYR A 189
ILE A 311
ILE A 260
 None
 0.82A 2q8hA-6cczA:
undetectable		 2q8hA-6cczA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eqc SCFV OF 9C12
ANTIBODY

(Mus musculus) 		no annotation 4 LEU D  80
TYR D  93
ILE D  82
ARG D  68
 None
 0.96A 2q8hA-6eqcD:
undetectable		 2q8hA-6eqcD:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6et9 ACETYL-COA
ACETYLTRANSFERASE
THIOLASE

(Methanothermococcus
thermolithotrophicus) 		no annotation 4 LEU A 216
TYR A   9
ARG A 344
ILE A 343
 None
 0.94A 2q8hA-6et9A:
undetectable		 2q8hA-6et9A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6geb DOTB

(Legionella
pneumophila) 		no annotation 4 LEU A 293
ILE A 169
ARG A 311
ILE A 141
 None
 0.93A 2q8hA-6gebA:
undetectable		 2q8hA-6gebA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ggp AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN

(Thermotoga
maritima) 		no annotation 4 LEU A  57
TYR A 111
ILE A 224
ILE A  92
 None
 0.86A 2q8hA-6ggpA:
undetectable		 2q8hA-6ggpA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gpc -

(-) 		no annotation 4 LEU A  38
TYR A  92
ILE A 119
ILE A  73
 None
 0.82A 2q8hA-6gpcA:
undetectable		 2q8hA-6gpcA:
undetectable