SIMILAR PATTERNS OF AMINO ACIDS FOR 2Q83_A_ADNA1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqj SUCCINYL-COA
SYNTHETASE ALPHA
CHAIN

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		4 ILE A 177
ILE A  92
LEU A  91
ILE A  93
 None
 0.83A 2q83A-1cqjA:
0.0		 2q83A-1cqjA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dub 2-ENOYL-COA
HYDRATASE

(Rattus
norvegicus) 		PF00378
(ECH_1) 		4 ILE A 151
CYH A 149
ILE A 126
ILE A  85
 None
 0.88A 2q83A-1dubA:
undetectable		 2q83A-1dubA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1egz ENDOGLUCANASE Z

(Dickeya
chrysanthemi) 		PF00150
(Cellulase) 		4 ILE A 214
ILE A 163
LEU A 162
ILE A 164
 None
 0.84A 2q83A-1egzA:
undetectable		 2q83A-1egzA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iu8 PYRROLIDONE-CARBOXYL
ATE PEPTIDASE

(Pyrococcus
horikoshii) 		PF01470
(Peptidase_C15) 		4 ILE A  73
ILE A 193
LEU A   5
ILE A  62
 None
 0.83A 2q83A-1iu8A:
undetectable		 2q83A-1iu8A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhe LEXA REPRESSOR

(Escherichia
coli) 		PF00717
(Peptidase_S24) 		4 ILE A 188
PRO A  87
ILE A 177
ILE A 149
 None
 0.88A 2q83A-1jheA:
undetectable		 2q83A-1jheA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhj APC10

(Homo sapiens) 		PF03256
(ANAPC10) 		4 ILE A 137
ILE A 120
LEU A 111
ILE A  94
 None
 0.86A 2q83A-1jhjA:
undetectable		 2q83A-1jhjA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jny ELONGATION FACTOR
1-ALPHA

(Sulfolobus
solfataricus) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 ILE A 307
ILE A 295
LEU A 259
ILE A 235
 None
 0.79A 2q83A-1jnyA:
undetectable		 2q83A-1jnyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1x 4-ALPHA-GLUCANOTRANS
FERASE

(Thermococcus
litoralis) 		PF03065
(Glyco_hydro_57)
PF09094
(DUF1925)
PF09095
(DUF1926) 		5 ILE A 634
PRO A 471
ILE A 470
LEU A 478
ILE A 474
 None
 1.31A 2q83A-1k1xA:
0.7		 2q83A-1k1xA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k6m 6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE
2-PHOSPHATASE

(Homo sapiens) 		PF00300
(His_Phos_1)
PF01591
(6PF2K) 		4 ILE A  45
ILE A 219
LEU A 243
ILE A 217
 None
AGS  A 503 ( 4.3A)
None
None
 0.85A 2q83A-1k6mA:
undetectable		 2q83A-1k6mA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)

(Tobacco etch
virus) 		PF00863
(Peptidase_C4) 		4 PRO A 154
ILE A  14
LEU A  98
ILE A  35
 None
 0.84A 2q83A-1lvmA:
undetectable		 2q83A-1lvmA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvp TATA BOX BINDING
PROTEIN

(Homo sapiens) 		PF00352
(TBP) 		4 ILE A 321
CYH A 262
ILE A 304
ILE A 328
 None
 0.85A 2q83A-1nvpA:
undetectable		 2q83A-1nvpA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nw1 CHOLINE KINASE (49.2
KD)

(Caenorhabditis
elegans) 		PF01633
(Choline_kinase) 		4 PRO A 139
ILE A 154
LEU A 262
ILE A 300
 None
 0.62A 2q83A-1nw1A:
14.7		 2q83A-1nw1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p49 STERYL-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase)
PF14707
(Sulfatase_C) 		4 ILE A  29
ILE A 322
LEU A 326
ILE A 272
 None
 0.89A 2q83A-1p49A:
undetectable		 2q83A-1p49A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qso HPA2 HISTONE
ACETYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF00583
(Acetyltransf_1) 		4 ILE A   9
ILE A 109
LEU A  93
ILE A  73
 None
 0.88A 2q83A-1qsoA:
undetectable		 2q83A-1qsoA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rzr GLUCOSE-RESISTANCE
AMYLASE REGULATOR

(Bacillus
megaterium) 		no annotation 4 ILE G 154
ILE G  66
LEU G 109
ILE G 120
 None
 0.77A 2q83A-1rzrG:
undetectable		 2q83A-1rzrG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s16 TOPOISOMERASE IV
SUBUNIT B

(Escherichia
coli) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		4 ILE A1312
ILE A1300
LEU A1301
ILE A1373
 None
 0.83A 2q83A-1s16A:
undetectable		 2q83A-1s16A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 37 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF08542
(Rep_fac_C) 		4 ILE B  47
PRO B  17
LEU B  20
ILE B  23
 None
AGS  B 802 (-4.4A)
None
AGS  B 802 (-4.4A)
 0.87A 2q83A-1sxjB:
2.0		 2q83A-1sxjB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t33 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR (TETR/ACRR
FAMILY)

(Salmonella
enterica) 		PF00440
(TetR_N)
PF09209
(DUF1956) 		4 ILE A  95
ILE A 214
LEU A 172
ILE A 211
 None
 0.86A 2q83A-1t33A:
undetectable		 2q83A-1t33A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1to6 GLYCERATE KINASE

(Neisseria
meningitidis) 		PF02595
(Gly_kinase) 		4 ILE A  23
CYH A  36
LEU A 366
ILE A  31
 None
 0.75A 2q83A-1to6A:
undetectable		 2q83A-1to6A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tv8 MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A

(Staphylococcus
aureus) 		PF04055
(Radical_SAM)
PF06463
(Mob_synth_C)
PF13394
(Fer4_14) 		4 ILE A 191
ILE A 148
LEU A 149
ILE A 152
 None
 0.80A 2q83A-1tv8A:
undetectable		 2q83A-1tv8A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Haemophilus
influenzae) 		PF02348
(CTP_transf_3) 		4 ILE A  93
ILE A 108
LEU A 126
ILE A 188
 None
 0.88A 2q83A-1vicA:
undetectable		 2q83A-1vicA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdw NAD+-DEPENDENT
(R)-2-HYDROXYGLUTARA
TE DEHYDROGENASE

(Acidaminococcus
fermentans) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A  64
ILE A  83
LEU A  51
ILE A  73
 None
 0.83A 2q83A-1xdwA:
undetectable		 2q83A-1xdwA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhl SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY MEMBER
(5L265), PUTATIVE
TROPINONE
REDUCTASE-II

(Caenorhabditis
elegans) 		PF13561
(adh_short_C2) 		4 ILE A 135
ILE A  77
LEU A  81
ILE A  87
 None
 0.86A 2q83A-1xhlA:
undetectable		 2q83A-1xhlA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xz9 AFADIN

(Homo sapiens) 		PF00595
(PDZ) 		4 ILE A  40
PRO A  10
ILE A  13
LEU A  57
 None
 0.88A 2q83A-1xz9A:
undetectable		 2q83A-1xz9A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zao RIO2 SERINE KINASE

(Archaeoglobus
fulgidus) 		PF01163
(RIO1)
PF09202
(Rio2_N) 		4 PRO A 167
ILE A 182
LEU A 225
ILE A 234
 ATP  A 286 ( 4.7A)
ATP  A 286 (-4.2A)
None
ATP  A 286 (-4.5A)
 0.63A 2q83A-1zaoA:
8.8		 2q83A-1zaoA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ahr PUTATIVE PYRROLINE
CARBOXYLATE
REDUCTASE

(Streptococcus
pyogenes) 		PF03807
(F420_oxidored)
PF14748
(P5CR_dimer) 		4 ILE A  84
ILE A  55
LEU A  54
ILE A   6
 None
 0.88A 2q83A-2ahrA:
undetectable		 2q83A-2ahrA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aie PEPTIDE DEFORMYLASE

(Streptococcus
pneumoniae) 		PF01327
(Pep_deformylase) 		4 ILE P  19
ILE P   3
LEU P  44
ILE P   6
 None
 0.84A 2q83A-2aieP:
undetectable		 2q83A-2aieP:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 CYH A1009
PRO A1006
ILE A1443
ILE A1401
 None
 0.88A 2q83A-2b39A:
undetectable		 2q83A-2b39A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fli RIBULOSE-PHOSPHATE
3-EPIMERASE

(Streptococcus
pyogenes) 		PF00834
(Ribul_P_3_epim) 		4 ILE A 116
PRO A  73
LEU A 102
ILE A  90
 None
 0.83A 2q83A-2fliA:
undetectable		 2q83A-2fliA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3n ALPHA-GLUCOSIDASE

(Sulfolobus
solfataricus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 ILE A 607
ILE A 660
LEU A 692
ILE A 651
 None
 0.89A 2q83A-2g3nA:
undetectable		 2q83A-2g3nA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gfq UPF0204 PROTEIN
PH0006

(Pyrococcus
horikoshii) 		PF04414
(tRNA_deacylase) 		5 ILE A  46
PRO A  71
ILE A  63
LEU A  59
ILE A  74
 None
 1.29A 2q83A-2gfqA:
undetectable		 2q83A-2gfqA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ics ADENINE DEAMINASE

(Enterococcus
faecalis) 		PF01979
(Amidohydro_1) 		5 ILE A 117
PRO A 194
ILE A 199
LEU A 202
ILE A 167
 KCX  A 154 ( 4.0A)
None
None
None
None
 1.26A 2q83A-2icsA:
undetectable		 2q83A-2icsA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ji9 OXALYL-COA
DECARBOXYLASE

(Oxalobacter
formigenes) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ILE A 139
PRO A  35
ILE A  36
LEU A  39
 None
 0.82A 2q83A-2ji9A:
undetectable		 2q83A-2ji9A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1x 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE

(Deinococcus
radiodurans) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
PF13292
(DXP_synthase_N) 		4 ILE A 152
ILE A  62
LEU A  65
ILE A  61
 None
 0.88A 2q83A-2o1xA:
undetectable		 2q83A-2o1xA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans) 		PF01933
(UPF0052) 		4 ILE A 215
ILE A 245
LEU A 196
ILE A 237
 None
 0.87A 2q83A-2o2zA:
undetectable		 2q83A-2o2zA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 ILE A 687
ILE A 752
LEU A 740
ILE A 749
 None
 0.83A 2q83A-2okxA:
undetectable		 2q83A-2okxA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p10 MLL9387 PROTEIN

(Mesorhizobium
japonicum) 		PF09370
(PEP_hydrolase) 		4 ILE A 185
CYH A 188
ILE A 245
LEU A 246
 None
 0.88A 2q83A-2p10A:
undetectable		 2q83A-2p10A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3v INOSITOL-1-MONOPHOSP
HATASE

(Thermotoga
maritima) 		PF00459
(Inositol_P) 		4 ILE A1078
ILE A1041
LEU A1018
ILE A1081
 None
 0.79A 2q83A-2p3vA:
undetectable		 2q83A-2p3vA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvz PRPF METHYLACONITATE
ISOMERASE

(Shewanella
oneidensis) 		PF04303
(PrpF) 		4 ILE A 267
ILE A 256
LEU A 205
ILE A 225
 None
 0.77A 2q83A-2pvzA:
undetectable		 2q83A-2pvzA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkc SUPEROXIDE DISMUTASE
[MN]

(Homo sapiens) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 ILE A  76
TRP A 125
LEU A 111
ILE A 158
 None
 0.88A 2q83A-2qkcA:
1.6		 2q83A-2qkcA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII

(Aspergillus
nidulans) 		PF00961
(LAGLIDADG_1) 		4 ILE Z 132
ILE Z 169
LEU Z 201
ILE Z 178
 None
 0.89A 2q83A-2qojZ:
undetectable		 2q83A-2qojZ:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vea PHYTOCHROME-LIKE
PROTEIN CPH1

(Synechocystis
sp. PCC 6803) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 ILE A 429
TRP A 439
LEU A 352
ILE A 370
 None
 0.85A 2q83A-2veaA:
undetectable		 2q83A-2veaA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w51 PROTEIN ARMET

(Homo sapiens) 		PF10208
(Armet) 		4 ILE A  32
ILE A  64
LEU A  85
ILE A  54
 None
 0.86A 2q83A-2w51A:
undetectable		 2q83A-2w51A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xme CTP-INOSITOL-1-PHOSP
HATE
CYTIDYLYLTRANSFERASE

(Archaeoglobus
fulgidus) 		PF12804
(NTP_transf_3) 		5 ILE A  63
PRO A  38
ILE A  73
LEU A  77
ILE A  48
 None
 1.36A 2q83A-2xmeA:
undetectable		 2q83A-2xmeA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 437
PRO A 307
ILE A 226
ILE A 421
 None
 0.85A 2q83A-2xybA:
undetectable		 2q83A-2xybA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbt PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS

(Thermus
thermophilus) 		PF01680
(SOR_SNZ) 		4 ILE A  69
ILE A  95
LEU A  96
ILE A  99
 None
 0.89A 2q83A-2zbtA:
undetectable		 2q83A-2zbtA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zts PUTATIVE
UNCHARACTERIZED
PROTEIN PH0186

(Pyrococcus
horikoshii) 		PF06745
(ATPase) 		4 ILE A 198
ILE A 127
LEU A 124
ILE A 167
 None
 0.83A 2q83A-2ztsA:
undetectable		 2q83A-2ztsA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2q 6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE

(Arthrobacter
sp. KI72) 		PF01425
(Amidase) 		4 ILE A 251
ILE A 453
LEU A 438
ILE A 436
 None
 0.81A 2q83A-3a2qA:
undetectable		 2q83A-3a2qA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753

(Sulfurisphaera
tokodaii) 		PF13456
(RVT_3) 		4 ILE A  57
PRO A  71
LEU A 113
ILE A  73
 None
 0.83A 2q83A-3alyA:
undetectable		 2q83A-3alyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bbl REGULATORY PROTEIN
OF LACI FAMILY

(Chloroflexus
aggregans) 		PF13377
(Peripla_BP_3) 		4 ILE A 279
ILE A 334
LEU A 333
ILE A 335
 None
 0.83A 2q83A-3bblA:
undetectable		 2q83A-3bblA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bw8 MONO-ADP-RIBOSYLTRAN
SFERASE C3

(Hathewaya
limosa) 		PF03496
(ADPrib_exo_Tox) 		4 ILE A 149
ILE A 103
LEU A 104
ILE A 110
 None
 0.89A 2q83A-3bw8A:
undetectable		 2q83A-3bw8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cer POSSIBLE
EXOPOLYPHOSPHATASE-L
IKE PROTEIN

(Bifidobacterium
longum) 		PF02541
(Ppx-GppA) 		5 ILE A  51
CYH A  23
PRO A 119
LEU A 115
ILE A 111
 None
 1.15A 2q83A-3cerA:
undetectable		 2q83A-3cerA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clk TRANSCRIPTION
REGULATOR

(Lactobacillus
plantarum) 		PF13377
(Peripla_BP_3) 		4 ILE A 122
ILE A  79
LEU A  80
ILE A  83
 None
 0.90A 2q83A-3clkA:
undetectable		 2q83A-3clkA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cm0 ADENYLATE KINASE

(Thermus
thermophilus) 		PF00406
(ADK) 		4 ILE A   8
ILE A  68
LEU A  69
ILE A  72
 None
 0.81A 2q83A-3cm0A:
undetectable		 2q83A-3cm0A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cu5 TWO COMPONENT
TRANSCRIPTIONAL
REGULATOR, ARAC
FAMILY

(Lachnoclostridium
phytofermentans) 		PF00072
(Response_reg) 		4 ILE A  39
PRO A  50
LEU A  74
ILE A  71
 None
 0.82A 2q83A-3cu5A:
undetectable		 2q83A-3cu5A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehg SENSOR KINASE (YOCF
PROTEIN)

(Bacillus
subtilis) 		no annotation 4 ILE A 307
ILE A 282
LEU A 344
ILE A 365
 None
 0.86A 2q83A-3ehgA:
undetectable		 2q83A-3ehgA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fo8 TAIL SHEATH PROTEIN
GP18

(Escherichia
virus T4) 		PF17481
(Phage_sheath_1N) 		4 ILE D 236
ILE D  95
LEU D 214
ILE D 219
 None
 0.87A 2q83A-3fo8D:
undetectable		 2q83A-3fo8D:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1n E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		PF00632
(HECT) 		4 ILE A4364
ILE A4259
LEU A4262
ILE A4257
 None
 0.85A 2q83A-3g1nA:
undetectable		 2q83A-3g1nA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g85 TRANSCRIPTIONAL
REGULATOR (LACI
FAMILY)

(Clostridium
acetobutylicum) 		PF13377
(Peripla_BP_3) 		5 ILE A 253
PRO A 290
ILE A 268
LEU A 261
ILE A 258
 None
 1.44A 2q83A-3g85A:
undetectable		 2q83A-3g85A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gr8 NADPH DEHYDROGENASE

(Geobacillus
kaustophilus) 		PF00724
(Oxidored_FMN) 		4 ILE A 278
ILE A 163
LEU A 197
ILE A 201
 None
 0.86A 2q83A-3gr8A:
undetectable		 2q83A-3gr8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwq D-SERINE DEAMINASE

(Paraburkholderia
xenovorans) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 ILE A 367
ILE A 321
LEU A 385
ILE A 379
 None
 0.88A 2q83A-3gwqA:
undetectable		 2q83A-3gwqA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h04 UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF07859
(Abhydrolase_3) 		4 ILE A 146
ILE A 175
LEU A 158
ILE A 155
 None
 0.86A 2q83A-3h04A:
undetectable		 2q83A-3h04A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
-C REDUCTASE COMPLEX
CORE PROTEIN 2

(Gallus gallus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 ILE B  35
ILE B 209
LEU B 379
ILE B 382
 None
 0.83A 2q83A-3h1lB:
0.7		 2q83A-3h1lB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ham AMINOGLYCOSIDE
PHOSPHOTRANSFERASE

(Enterococcus
faecium) 		PF01636
(APH) 		4 ILE A 283
ILE A 271
LEU A 150
ILE A 153
 None
 0.71A 2q83A-3hamA:
14.6		 2q83A-3hamA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjz TRANSALDOLASE B

(Prochlorococcus
marinus) 		PF00923
(TAL_FSA) 		4 ILE A 154
ILE A 143
LEU A 158
ILE A 175
 None
 0.87A 2q83A-3hjzA:
undetectable		 2q83A-3hjzA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN

(Syntrophus
aciditrophicus) 		PF12694
(MoCo_carrier) 		4 ILE A 110
ILE A  78
LEU A  77
ILE A  79
 GOL  A 159 ( 4.1A)
None
None
None
 0.85A 2q83A-3imkA:
undetectable		 2q83A-3imkA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C) 		PF06016
(Reovirus_L2) 		4 PRO W 548
ILE W 537
LEU W 534
ILE W 551
 None
 0.87A 2q83A-3iylW:
undetectable		 2q83A-3iylW:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j5y EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1

(Homo sapiens) 		PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		4 ILE A 120
ILE A  21
LEU A  20
ILE A  17
 None
 0.87A 2q83A-3j5yA:
undetectable		 2q83A-3j5yA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jtj 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Yersinia pestis) 		PF02348
(CTP_transf_3) 		4 ILE A  93
ILE A 108
LEU A 126
ILE A 184
 None
 0.86A 2q83A-3jtjA:
undetectable		 2q83A-3jtjA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9d ALDEHYDE
DEHYDROGENASE

(Listeria
monocytogenes) 		PF00171
(Aldedh) 		4 ILE A  39
PRO A 436
ILE A 131
ILE A  85
 None
 0.88A 2q83A-3k9dA:
undetectable		 2q83A-3k9dA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kgw ALANINE-GLYOXYLATE
AMINOTRANSFERASE

(Mus musculus) 		PF00266
(Aminotran_5) 		4 ILE A 242
PRO A 287
LEU A 294
ILE A 239
 None
 0.84A 2q83A-3kgwA:
undetectable		 2q83A-3kgwA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl4 SIGNAL RECOGNITION
54 KDA PROTEIN

(Sulfolobus
solfataricus) 		PF00448
(SRP54)
PF02881
(SRP54_N)
PF02978
(SRP_SPB) 		4 ILE A 183
ILE A 276
LEU A 146
ILE A 150
 None
 0.89A 2q83A-3kl4A:
undetectable		 2q83A-3kl4A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3krz NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE

(Thermoanaerobacter
pseudethanolicus) 		PF00724
(Oxidored_FMN) 		4 ILE A 278
ILE A 162
LEU A 196
ILE A 200
 None
 0.89A 2q83A-3krzA:
undetectable		 2q83A-3krzA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ly9 TRANSCRIPTIONAL
ACTIVATOR CADC

(Escherichia
coli) 		no annotation 4 ILE A 440
ILE A 418
LEU A 381
ILE A 422
 None
 0.87A 2q83A-3ly9A:
undetectable		 2q83A-3ly9A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mes CHOLINE KINASE

(Cryptosporidium
parvum) 		PF01633
(Choline_kinase) 		5 ILE A  78
PRO A 137
ILE A 152
LEU A 275
ILE A 284
 None
ADP  A 425 ( 4.7A)
ADP  A 425 (-4.4A)
None
None
 0.81A 2q83A-3mesA:
12.3		 2q83A-3mesA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3muo PROLYL ENDOPEPTIDASE

(Aeromonas
caviae) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 ILE A 454
ILE A 438
LEU A 437
ILE A 439
 ZPR  A 702 ( 4.3A)
None
None
None
 0.90A 2q83A-3muoA:
undetectable		 2q83A-3muoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n4t APH(2'')-ID

(Enterococcus
casseliflavus) 		PF01636
(APH) 		4 PRO A  76
ILE A  98
LEU A 204
ILE A 216
 None
 0.66A 2q83A-3n4tA:
15.5		 2q83A-3n4tA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nie MAP2 KINASE

(Plasmodium
falciparum) 		PF00069
(Pkinase) 		4 ILE A 404
PRO A  98
LEU A  95
ILE A 409
 None
 0.84A 2q83A-3nieA:
2.8		 2q83A-3nieA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Vibrio cholerae) 		PF02348
(CTP_transf_3) 		4 ILE A  93
ILE A 108
LEU A 126
ILE A 184
 None
 0.82A 2q83A-3oamA:
undetectable		 2q83A-3oamA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oml PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2,
CG3415

(Drosophila
melanogaster) 		PF00106
(adh_short)
PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		4 ILE A 149
CYH A 229
ILE A 240
ILE A 195
 None
 0.89A 2q83A-3omlA:
undetectable		 2q83A-3omlA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opx PROTEIN SSM1

(Saccharomyces
cerevisiae) 		PF13419
(HAD_2) 		4 ILE A 208
ILE A 244
LEU A 247
ILE A 241
 None
 0.81A 2q83A-3opxA:
undetectable		 2q83A-3opxA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdi NITROGENASE MOFE
COFACTOR
BIOSYNTHESIS PROTEIN
NIFE
NITROGENASE MOFE
COFACTOR
BIOSYNTHESIS PROTEIN
NIFN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro) 		4 ILE B  28
PRO A  30
LEU B  84
ILE B  87
 None
 0.85A 2q83A-3pdiB:
undetectable		 2q83A-3pdiB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q2k OXIDOREDUCTASE

(Bordetella
pertussis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 ILE A 271
ILE A 145
LEU A 199
ILE A 254
 None
 0.89A 2q83A-3q2kA:
undetectable		 2q83A-3q2kA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qp4 CVIR TRANSCRIPTIONAL
REGULATOR

(Chromobacterium
violaceum) 		PF03472
(Autoind_bind) 		4 PRO A 161
TRP A 111
ILE A 139
ILE A 156
 None
HL0  A   1 (-4.1A)
None
None
 0.88A 2q83A-3qp4A:
undetectable		 2q83A-3qp4A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpt TRANSCRIPTIONAL
REGULATOR SLYA

(Salmonella
enterica) 		PF01047
(MarR) 		4 ILE A 130
ILE A 118
LEU A 115
ILE A 123
 None
 0.84A 2q83A-3qptA:
undetectable		 2q83A-3qptA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyy RESPONSE REGULATOR

(Xanthomonas
campestris) 		PF00990
(GGDEF) 		4 CYH A 149
TRP A 209
LEU A 204
ILE A 210
 None
 0.87A 2q83A-3qyyA:
undetectable		 2q83A-3qyyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage 201phi2-1) 		PF00091
(Tubulin) 		4 ILE A  63
ILE A 102
LEU A  74
ILE A  71
 None
 0.74A 2q83A-3r4vA:
undetectable		 2q83A-3r4vA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3skq MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
38

(Saccharomyces
cerevisiae) 		PF07766
(LETM1) 		5 ILE A 395
PRO A 405
ILE A 204
LEU A 203
ILE A 402
 None
 1.14A 2q83A-3skqA:
undetectable		 2q83A-3skqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tl8 EFFECTOR PROTEIN
HOPAB2

(Pseudomonas
syringae group
genomosp. 3) 		PF16847
(AvrPtoB_bdg) 		4 PRO B 314
ILE B 313
LEU B 321
ILE B 317
 None
 0.89A 2q83A-3tl8B:
undetectable		 2q83A-3tl8B:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uws HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF03415
(Peptidase_C11) 		4 ILE B 264
PRO B 352
LEU B 276
ILE B 273
 None
 0.85A 2q83A-3uwsB:
undetectable		 2q83A-3uwsB:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wqu CELL DIVISION
PROTEIN FTSA

(Staphylococcus
aureus) 		PF02491
(SHS2_FTSA)
PF14450
(FtsA) 		4 ILE A 112
PRO A 142
LEU A 375
ILE A 105
 None
 0.84A 2q83A-3wquA:
undetectable		 2q83A-3wquA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wt0 CELL DIVISION
PROTEIN FTSA

(Staphylococcus
aureus) 		PF02491
(SHS2_FTSA)
PF14450
(FtsA) 		4 ILE A 112
PRO A 142
LEU A 375
ILE A 105
 None
 0.76A 2q83A-3wt0A:
undetectable		 2q83A-3wt0A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wya ELONGATION FACTOR
1-ALPHA

(Pyrococcus
horikoshii) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		5 ILE A  13
PRO A 176
ILE A 178
LEU A 203
ILE A 140
 None
 1.39A 2q83A-3wyaA:
undetectable		 2q83A-3wyaA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wya ELONGATION FACTOR
1-ALPHA

(Pyrococcus
horikoshii) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 ILE A 301
ILE A 289
LEU A 247
ILE A 223
 None
 0.81A 2q83A-3wyaA:
undetectable		 2q83A-3wyaA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apw ALP12

(Clostridium
tetani) 		no annotation 4 ILE A 136
ILE A 130
LEU A 108
ILE A 149
 None
 0.67A 2q83A-4apwA:
undetectable		 2q83A-4apwA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwf UBIQUITIN-CONJUGATIN
G ENZYME E2-21 KDA

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		4 ILE A  47
PRO A  93
LEU A 116
ILE A  95
 None
 0.89A 2q83A-4bwfA:
undetectable		 2q83A-4bwfA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwv PHOSPHOADENOSINE-PHO
SPHOSULPHATE
REDUCTASE

(Physcomitrella
patens) 		PF01507
(PAPS_reduct) 		5 ILE A 143
PRO A 248
ILE A 125
LEU A 129
ILE A 221
 None
 1.48A 2q83A-4bwvA:
undetectable		 2q83A-4bwvA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN

(Carboxydothermus
hydrogenoformans) 		PF14574
(DUF4445) 		4 ILE I 424
PRO I 441
ILE I 500
ILE I 419
 None
 0.87A 2q83A-4c1nI:
undetectable		 2q83A-4c1nI:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cxh ELONGATION FACTOR 1A

(Oryctolagus
cuniculus) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 ILE A 307
ILE A 295
LEU A 259
ILE A 235
 None
 0.89A 2q83A-4cxhA:
undetectable		 2q83A-4cxhA:
20.81