SIMILAR PATTERNS OF AMINO ACIDS FOR 2Q72_A_IXXA802

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)

(Homo sapiens) 		PF00554
(RHD_DNA_bind)
PF16179
(RHD_dimer) 		4 ILE A 230
SER A 318
ARG A 261
PHE A 289
 None
 0.79A 2q72A-1a3qA:
2.8		 2q72A-1a3qA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b5t PROTEIN
(METHYLENETETRAHYDRO
FOLATE REDUCTASE)

(Escherichia
coli) 		PF02219
(MTHFR) 		4 ILE A 286
ARG A 293
ILE A  23
PHE A 272
 None
 1.15A 2q72A-1b5tA:
0.0		 2q72A-1b5tA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 ILE A 359
ARG A 435
ILE A 439
PHE A 409
 None
 0.87A 2q72A-1c30A:
0.0		 2q72A-1c30A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fok PROTEIN (FOKI
RESTRICTION
ENDONUCLEASE)

(Planomicrobium
okeanokoites) 		PF02980
(FokI_C)
PF02981
(FokI_N)
PF09254
(Endonuc-FokI_C)
PF16902
(Type2_restr_D3) 		4 ILE A 352
ARG A 310
ARG A 309
ILE A 344
 None
 0.95A 2q72A-1fokA:
0.0		 2q72A-1fokA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fxz GLYCININ G1

(Glycine max) 		PF00190
(Cupin_1) 		4 ILE A 306
ARG A 303
ILE A  72
PHE A 415
 None
 1.15A 2q72A-1fxzA:
undetectable		 2q72A-1fxzA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq1 CYTOCHROME CD1
NITRITE REDUCTASE

(Paracoccus
pantotrophus) 		PF02239
(Cytochrom_D1)
PF13442
(Cytochrome_CBB3) 		4 ILE A 179
SER A 170
ARG A 203
ILE A 245
 None
None
DHE  A 602 (-3.5A)
None
 1.05A 2q72A-1gq1A:
0.0		 2q72A-1gq1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hv8 PUTATIVE
ATP-DEPENDENT RNA
HELICASE MJ0669

(Methanocaldococcus
jannaschii) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 ILE A  79
ARG A 180
ILE A  47
PHE A 184
 None
 0.96A 2q72A-1hv8A:
0.0		 2q72A-1hv8A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j26 IMMATURE COLON
CARCINOMA TRANSCRIPT
1

(Mus musculus) 		PF00472
(RF-1) 		4 ILE A  17
SER A  14
ILE A  64
PHE A  48
 None
 0.86A 2q72A-1j26A:
undetectable		 2q72A-1j26A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3u ASPARTASE

(Bacillus sp.
YM55-1) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 ILE A 291
ARG A 296
ILE A 309
PHE A 201
 None
 1.12A 2q72A-1j3uA:
0.1		 2q72A-1j3uA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jrm CONSERVED
HYPOTHETICAL PROTEIN
MTH637

(Methanothermobacter
thermautotrophicus) 		PF02594
(DUF167) 		4 ILE A   2
ARG A  36
ILE A  18
PHE A  91
 None
 1.11A 2q72A-1jrmA:
undetectable		 2q72A-1jrmA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mu2 HIV-2 RT

(Human
immunodeficiency
virus 2) 		PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		4 ILE A 504
SER A 507
ILE A 530
PHE A 481
 None
 1.17A 2q72A-1mu2A:
0.0		 2q72A-1mu2A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nub BASEMENT MEMBRANE
PROTEIN BM-40

(Homo sapiens) 		PF00050
(Kazal_1)
PF09289
(FOLN)
PF10591
(SPARC_Ca_bdg) 		4 ILE A 129
SER A 105
ILE A  88
PHE A  91
 None
 1.12A 2q72A-1nubA:
undetectable		 2q72A-1nubA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1poj ISOASPARTYL
DIPEPTIDASE

(Escherichia
coli) 		PF01979
(Amidohydro_1) 		4 ILE A  65
SER A  99
ARG A 157
ILE A 159
 None
 1.17A 2q72A-1pojA:
undetectable		 2q72A-1pojA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svc PROTEIN (NUCLEAR
FACTOR KAPPA-B
(NF-KB))

(Homo sapiens) 		PF00554
(RHD_DNA_bind)
PF16179
(RHD_dimer) 		4 ILE P 253
SER P 343
ARG P 284
PHE P 314
 None
 0.91A 2q72A-1svcP:
undetectable		 2q72A-1svcP:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5w MEIOTIC
RECOMBINATION
PROTEIN DMC1/LIM15
HOMOLOG

(Homo sapiens) 		PF08423
(Rad51) 		4 ILE A 315
SER A 318
ILE A 116
PHE A 108
 None
 0.96A 2q72A-1v5wA:
undetectable		 2q72A-1v5wA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpm ACYL-COA HYDROLASE

(Bacillus
halodurans) 		PF03061
(4HBT) 		4 ILE A  38
ARG A  16
ILE A  29
PHE A  64
 None
 1.03A 2q72A-1vpmA:
undetectable		 2q72A-1vpmA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w33 BBCRASP-1

(Borreliella
burgdorferi) 		PF05714
(Borrelia_lipo_1) 		4 ILE A 163
SER A 167
ILE A 139
PHE A 104
 None
 1.12A 2q72A-1w33A:
undetectable		 2q72A-1w33A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wac P2 PROTEIN

(Pseudomonas
virus phi6) 		PF00680
(RdRP_1) 		4 ILE A 283
SER A 360
ILE A 340
PHE A 135
 None
 1.10A 2q72A-1wacA:
0.8		 2q72A-1wacA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfi UNKNOWN PROTEIN

(Arabidopsis
thaliana) 		PF01937
(DUF89) 		4 ILE A 254
SER A 253
ARG A 105
PHE A  49
 None
 1.09A 2q72A-1xfiA:
undetectable		 2q72A-1xfiA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yz6 PROBABLE TRANSLATION
INITIATION FACTOR 2
ALPHA SUBUNIT

(Pyrococcus
abyssi) 		PF00575
(S1)
PF07541
(EIF_2_alpha) 		4 ILE A 251
ARG A 201
ILE A 243
PHE A 182
 None
 1.00A 2q72A-1yz6A:
undetectable		 2q72A-1yz6A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1

(Thermotoga
maritima) 		PF02127
(Peptidase_M18) 		4 ILE A  45
SER A  49
ARG A  79
PHE A 276
 None
 0.97A 2q72A-2glfA:
undetectable		 2q72A-2glfA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h9f HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF04303
(PrpF) 		4 ILE A   9
ARG A  25
ILE A  73
PHE A  44
 None
SO4  A 402 (-3.3A)
None
None
 0.99A 2q72A-2h9fA:
undetectable		 2q72A-2h9fA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9i HYPOTHETICAL PROTEIN

(Helicobacter
pylori) 		PF05211
(NLBH) 		4 ILE A  88
ARG A 122
ILE A 109
PHE A 178
 None
 1.15A 2q72A-2i9iA:
undetectable		 2q72A-2i9iA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jh9 VP4 CORE PROTEIN

(Bluetongue
virus) 		PF05059
(Orbi_VP4) 		4 ILE A 433
SER A 431
ARG A 406
ILE A 130
 None
 1.15A 2q72A-2jh9A:
undetectable		 2q72A-2jh9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jmr FIMF

(Escherichia
coli) 		PF00419
(Fimbrial) 		4 ILE A 172
ARG A  51
ILE A  52
PHE A  68
 None
 1.13A 2q72A-2jmrA:
undetectable		 2q72A-2jmrA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kr5 AFLATOXIN
BIOSYNTHESIS
POLYKETIDE SYNTHASE

(Aspergillus
parasiticus) 		PF00550
(PP-binding) 		4 ILE A  26
ARG A  53
ILE A  50
PHE A  37
 None
 1.16A 2q72A-2kr5A:
undetectable		 2q72A-2kr5A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5p FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07660
(STN)
PF07715
(Plug) 		4 ILE A 185
SER A 238
ARG A 270
ILE A 269
 None
 0.84A 2q72A-2o5pA:
undetectable		 2q72A-2o5pA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa2 TREHALOSE-SYNTHASE
TRET

(Pyrococcus
horikoshii) 		PF00534
(Glycos_transf_1) 		4 ILE A  58
SER A  61
ARG A  14
ILE A 399
 None
 1.06A 2q72A-2xa2A:
undetectable		 2q72A-2xa2A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0l EARLY ANTIGEN
PROTEIN D

(Human
gammaherpesvirus
4) 		PF04929
(Herpes_DNAp_acc) 		4 SER A 291
ARG A 266
ILE A 272
PHE A 295
 None
 1.17A 2q72A-2z0lA:
undetectable		 2q72A-2z0lA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF06405
(RCC_reductase) 		4 ILE A 135
SER A 137
ILE A 312
PHE A 296
 None
 1.14A 2q72A-3agbA:
undetectable		 2q72A-3agbA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiv BETA-GLUCOSIDASE

(Secale cereale) 		PF00232
(Glyco_hydro_1) 		4 ILE A 104
ARG A 101
ILE A 257
PHE A 176
 None
 1.00A 2q72A-3aivA:
undetectable		 2q72A-3aivA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2r CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		4 ILE A 599
ARG A 577
ILE A 556
PHE A 619
 None
 1.10A 2q72A-3b2rA:
undetectable		 2q72A-3b2rA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjc CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		4 ILE A 599
ARG A 577
ILE A 556
PHE A 619
 None
 1.12A 2q72A-3bjcA:
0.9		 2q72A-3bjcA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e13 PUTATIVE IRON-UPTAKE
ABC TRANSPORT
SYSTEM,PERIPLASMIC
IRON-BINDING PROTEIN

(Campylobacter
jejuni) 		PF13343
(SBP_bac_6) 		4 ILE X 224
ARG X 107
ILE X 236
PHE X 294
 None
 1.02A 2q72A-3e13X:
undetectable		 2q72A-3e13X:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyc PUTATIVE GLYCOSIDE
HYDROLASE

(Parabacteroides
distasonis) 		PF12876
(Cellulase-like) 		4 ILE A 396
SER A 399
ARG A 362
ILE A 313
 None
 0.99A 2q72A-3gycA:
undetectable		 2q72A-3gycA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdx SUSD SUPERFAMILY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ILE A 498
ARG A 111
ILE A 116
PHE A 178
 None
 1.17A 2q72A-3hdxA:
undetectable		 2q72A-3hdxA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 ILE B 580
ARG B 545
ARG B 544
PHE B 604
 None
 1.09A 2q72A-3hkzB:
undetectable		 2q72A-3hkzB:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hyi PROTEIN DUF199/WHIA

(Thermotoga
maritima) 		PF02650
(HTH_WhiA)
PF10298
(WhiA_N)
PF14527
(LAGLIDADG_WhiA) 		4 ILE A  13
SER A  10
ILE A 136
PHE A 181
 None
 1.12A 2q72A-3hyiA:
1.6		 2q72A-3hyiA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jv4 NUCLEAR FACTOR
NF-KAPPA-B P105
SUBUNIT

(Mus musculus) 		PF16179
(RHD_dimer) 		4 ILE B 250
SER B 340
ARG B 281
PHE B 311
 None
 1.03A 2q72A-3jv4B:
undetectable		 2q72A-3jv4B:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jv5 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT

(Mus musculus) 		PF16179
(RHD_dimer) 		4 ILE A 230
SER A 318
ARG A 261
PHE A 289
 None
 0.92A 2q72A-3jv5A:
undetectable		 2q72A-3jv5A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd6 CARBOHYDRATE KINASE,
PFKB FAMILY

(Chlorobaculum
tepidum) 		PF00294
(PfkB) 		4 ILE A 126
SER A  28
ILE A  72
PHE A 107
 None
AMP  A 509 ( 4.5A)
None
None
 1.08A 2q72A-3kd6A:
undetectable		 2q72A-3kd6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksc LEGA CLASS

(Pisum sativum) 		PF00190
(Cupin_1) 		4 ILE A 326
ARG A 323
ILE A  70
PHE A 435
 None
GOL  A 499 (-3.3A)
None
None
 1.06A 2q72A-3kscA:
undetectable		 2q72A-3kscA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpx DNA GYRASE, A
SUBUNIT

(Colwellia
psychrerythraea) 		PF00521
(DNA_topoisoIV) 		4 ILE A 130
SER A 133
ARG A 162
ILE A 191
 None
 1.15A 2q72A-3lpxA:
undetectable		 2q72A-3lpxA:
23.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		5 ILE A 178
SER A 181
ARG A 185
ILE A 197
PHE A 350
 None
 0.15A 2q72A-3mpnA:
67.9		 2q72A-3mpnA:
99.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqr MAGNESIUM AND COBALT
EFFLUX PROTEIN CORC

(Salmonella
enterica) 		PF00571
(CBS) 		4 ILE A 169
SER A 176
ARG A  70
ARG A  68
 None
 1.15A 2q72A-3nqrA:
undetectable		 2q72A-3nqrA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qty PHOSPHORIBOSYLAMINOI
MIDAZOLE (AIR)
SYNTHETASE

(Francisella
tularensis) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 283
ARG A 289
ILE A 293
PHE A 302
 None
 0.73A 2q72A-3qtyA:
undetectable		 2q72A-3qtyA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6y ASPARTASE

(Bacillus sp.
YM55-1) 		PF00206
(Lyase_1) 		4 ILE A 291
ARG A 296
ILE A 309
PHE A 201
 ILE  A 291 ( 0.7A)
ARG  A 296 ( 0.6A)
ILE  A 309 ( 0.7A)
PHE  A 201 ( 1.3A)
 1.14A 2q72A-3r6yA:
undetectable		 2q72A-3r6yA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rhg PUTATIVE
PHOPHOTRIESTERASE

(Proteus
mirabilis) 		PF02126
(PTE) 		4 ILE A 101
SER A 100
ARG A 134
ILE A 167
 UNL  A 374 ( 3.7A)
None
None
None
 1.16A 2q72A-3rhgA:
0.3		 2q72A-3rhgA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rw7 NUCLEAR RNA EXPORT
FACTOR 1

(Homo sapiens) 		PF09162
(Tap-RNA_bind) 		4 ILE A 286
SER A 285
ARG A 258
ILE A 259
 None
 1.11A 2q72A-3rw7A:
undetectable		 2q72A-3rw7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t05 PYRUVATE KINASE

(Staphylococcus
aureus) 		PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C) 		4 ILE A 232
SER A 236
ARG A 204
ILE A 170
 None
 1.00A 2q72A-3t05A:
undetectable		 2q72A-3t05A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akk NITRATE REGULATORY
PROTEIN

(Klebsiella
oxytoca) 		PF03861
(ANTAR)
PF08376
(NIT) 		4 ILE A 135
ARG A 137
ILE A 142
PHE A  82
 None
 1.09A 2q72A-4akkA:
0.7		 2q72A-4akkA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arc LEUCINE--TRNA LIGASE

(Escherichia
coli) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		4 ILE A 768
ARG A 643
ILE A 726
PHE A 669
 None
 1.05A 2q72A-4arcA:
undetectable		 2q72A-4arcA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzi SEC23P

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 ILE A 379
ARG A 386
ILE A 612
PHE A 608
 None
 1.15A 2q72A-4bziA:
undetectable		 2q72A-4bziA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4j ARGININE DEIMINASE

(Mycoplasma
penetrans) 		PF02274
(Amidinotransf) 		4 ILE A  61
SER A  59
ILE A 364
PHE A 326
 None
 1.14A 2q72A-4e4jA:
undetectable		 2q72A-4e4jA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6p PROBABLE SORBITOL
DEHYDROGENASE
(L-IDITOL
2-DEHYDROGENASE)

(Sinorhizobium
meliloti) 		PF13561
(adh_short_C2) 		4 ILE A  18
ARG A  16
ARG A  42
ILE A  35
 None
 1.17A 2q72A-4e6pA:
undetectable		 2q72A-4e6pA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd6 ARYLALKYLAMINE
N-ACETYLTRANSFERASE
2

(Aedes aegypti) 		PF00583
(Acetyltransf_1) 		4 ILE A 133
SER A 155
ARG A 162
ILE A  83
 None
 1.17A 2q72A-4fd6A:
undetectable		 2q72A-4fd6A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfj TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 ILE A 377
ARG A  90
ARG A  93
ILE A 388
 None
 1.06A 2q72A-4gfjA:
1.1		 2q72A-4gfjA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gtn ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Acinetobacter
sp. ADP1) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 ILE A 308
SER A 306
ILE A 316
PHE A 111
 None
 1.13A 2q72A-4gtnA:
undetectable		 2q72A-4gtnA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hi5 MATRIX PROTEIN

(Borna disease
virus) 		PF16520
(BDV_M) 		4 ILE A  15
SER A  44
ARG A 138
ILE A 137
 None
 1.03A 2q72A-4hi5A:
undetectable		 2q72A-4hi5A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kjr CATION EXCHANGER
YFKE

(Bacillus
subtilis) 		PF01699
(Na_Ca_ex) 		4 ILE A  87
SER A  91
ILE A  74
PHE A  78
 None
 1.18A 2q72A-4kjrA:
undetectable		 2q72A-4kjrA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kwm HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 ILE A  79
SER A 262
ILE A 256
PHE A 111
 None
 0.98A 2q72A-4kwmA:
undetectable		 2q72A-4kwmA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ld8 MATRIX PROTEIN VP40

(Sudan
ebolavirus) 		PF07447
(VP40) 		4 ILE A 285
ARG A 204
ILE A 240
PHE A 247
 None
 0.99A 2q72A-4ld8A:
undetectable		 2q72A-4ld8A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ntj P2Y PURINOCEPTOR
12,SOLUBLE
CYTOCHROME B562,P2Y
PURINOCEPTOR 12

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		4 ILE A  61
SER A  55
ILE A  68
PHE A 114
 None
 1.10A 2q72A-4ntjA:
undetectable		 2q72A-4ntjA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0d TRYPSIN-RESISTANT
SURFACE T6 PROTEIN

(Streptococcus
pyogenes) 		PF16569
(GramPos_pilinBB) 		4 ILE A 480
SER A 452
ILE A 466
PHE A 463
 None
 1.08A 2q72A-4p0dA:
undetectable		 2q72A-4p0dA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pd4 CYTOCHROME B

(Saccharomyces
cerevisiae) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B) 		4 SER C 311
ARG C 107
ARG C 314
ILE C 212
 None
 1.17A 2q72A-4pd4C:
undetectable		 2q72A-4pd4C:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh0 SPORE PHOTOPRODUCT
LYASE

(Geobacillus
thermodenitrificans) 		no annotation 4 ILE A 144
SER A 142
ARG A  68
ILE A 118
 None
None
SO4  A 403 (-3.0A)
None
 1.14A 2q72A-4rh0A:
undetectable		 2q72A-4rh0A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzi 3-KETOACYL-ACYL
CARRIER PROTEIN
REDUCTASE

(Synechocystis
sp. PCC 6803) 		no annotation 4 ILE B 135
SER B 136
ILE B 188
PHE B 205
 None
 1.06A 2q72A-4rziB:
undetectable		 2q72A-4rziB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uhh ESTERASE

(Thermogutta
terrifontis) 		PF00561
(Abhydrolase_1) 		4 ILE A   7
ARG A 117
ILE A  56
PHE A  20
 None
 1.11A 2q72A-4uhhA:
undetectable		 2q72A-4uhhA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C

(Acetivibrio
cellulolyticus) 		PF00963
(Cohesin) 		4 ILE A  31
ARG A  85
ILE A  56
PHE A  93
 None
 1.14A 2q72A-4uypA:
undetectable		 2q72A-4uypA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9u KIWELLIN

(Actinidia
deliciosa) 		no annotation 4 ILE A 162
SER A 110
ARG A 119
ILE A 124
 None
 1.00A 2q72A-4x9uA:
undetectable		 2q72A-4x9uA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 ILE A 364
SER A 317
ILE A 391
PHE A 436
 None
 1.11A 2q72A-4xmvA:
undetectable		 2q72A-4xmvA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z1a 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE

(Helicobacter
pylori) 		PF00793
(DAHP_synth_1) 		4 ILE A 117
SER A 121
ARG A 151
ILE A 155
 None
 1.11A 2q72A-4z1aA:
undetectable		 2q72A-4z1aA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpt MGC81278 PROTEIN

(Xenopus laevis) 		PF12894
(ANAPC4_WD40)
PF12896
(ANAPC4) 		4 ILE A 693
ARG A 696
ILE A 593
PHE A 581
 None
 1.14A 2q72A-5bptA:
undetectable		 2q72A-5bptA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila) 		PF12009
(Telomerase_RBD) 		4 ILE A 488
ARG A 473
ILE A 469
PHE A 408
 None
A  D  10 ( 4.2A)
None
None
 0.94A 2q72A-5c9hA:
1.0		 2q72A-5c9hA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e32 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 ILE A  87
SER A 265
ILE A 260
PHE A 118
 None
 1.11A 2q72A-5e32A:
undetectable		 2q72A-5e32A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 ILE A 496
SER A 495
ILE A 467
PHE A 371
 None
 1.07A 2q72A-5ereA:
undetectable		 2q72A-5ereA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exr DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
PF08996
(zf-DNA_Pol) 		4 ILE C 629
ARG C 664
ILE C 662
PHE C 622
 None
 0.97A 2q72A-5exrC:
undetectable		 2q72A-5exrC:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey8 ACYL-COA SYNTHASE

(Mycolicibacterium
smegmatis) 		PF00501
(AMP-binding) 		4 ILE A 489
SER A 520
ARG A 608
ARG A 605
 None
 1.01A 2q72A-5ey8A:
undetectable		 2q72A-5ey8A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fuu HIV-1 ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 ILE A 423
SER A 195
ARG A 192
PHE A 176
 None
 0.96A 2q72A-5fuuA:
undetectable		 2q72A-5fuuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjw VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1

(Oryctolagus
cuniculus) 		PF00092
(VWA)
PF08399
(VWA_N)
PF08473
(VGCC_alpha2) 		4 ILE F 743
ARG F 707
ILE F 705
PHE F 686
 None
 1.13A 2q72A-5gjwF:
undetectable		 2q72A-5gjwF:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gwp ABA RECEPTOR RCAR3

(Oryza sativa) 		PF10604
(Polyketide_cyc2) 		4 ILE C 138
SER C 136
ARG C 110
ILE C  90
 None
 1.07A 2q72A-5gwpC:
undetectable		 2q72A-5gwpC:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hyh UNCHARACTERIZED
PROTEIN

(Streptomyces
venezuelae) 		PF11583
(AurF) 		4 ILE A 206
SER A 243
ILE A 108
PHE A 273
 None
 1.12A 2q72A-5hyhA:
undetectable		 2q72A-5hyhA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6e ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF08326
(ACC_central) 		4 ILE A1347
ARG A1363
ILE A1342
PHE A1393
 None
 1.09A 2q72A-5i6eA:
undetectable		 2q72A-5i6eA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iud DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 ILE A 629
ARG A 664
ILE A 662
PHE A 622
 None
 1.02A 2q72A-5iudA:
undetectable		 2q72A-5iudA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j8q CYSTEINE DESULFURASE
SUFS

(Bacillus
subtilis) 		PF00266
(Aminotran_5) 		4 ILE A 299
SER A 300
ILE A 208
PHE A  77
 None
 1.12A 2q72A-5j8qA:
undetectable		 2q72A-5j8qA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5p PRE-MRNA-SPLICING
HELICASE BRR2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 ILE A1762
ARG A1458
ARG A1462
ILE A1465
 None
 1.13A 2q72A-5m5pA:
undetectable		 2q72A-5m5pA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mp0 M7GPPPN-MRNA
HYDROLASE

(Homo sapiens) 		PF00293
(NUDIX) 		4 ILE D 176
ARG D 233
ILE D 232
PHE D 126
 None
 1.07A 2q72A-5mp0D:
undetectable		 2q72A-5mp0D:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogz -

(-) 		no annotation 4 ILE A  80
ARG A  77
ILE A 217
PHE A 151
 None
 1.07A 2q72A-5ogzA:
undetectable		 2q72A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5okl AFAMIN

(Homo sapiens) 		no annotation 4 ILE A 219
SER A 223
ARG A 339
ARG A 340
 None
 0.99A 2q72A-5oklA:
undetectable		 2q72A-5oklA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vc7 VCP-LIKE ATPASE

(Thermoplasma
acidophilum) 		PF00004
(AAA) 		4 ILE A 563
SER A 525
ILE A 479
PHE A 504
 None
 1.13A 2q72A-5vc7A:
2.1		 2q72A-5vc7A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vlj NUCLEAR DISTRIBUTION
PROTEIN PAC1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 ILE B 340
SER B 302
ILE B 387
PHE B 407
 None
 0.94A 2q72A-5vljB:
undetectable		 2q72A-5vljB:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wos CNPV058 BCL-2 LIKE
PROTEIN

(Canarypox virus) 		no annotation 4 ILE A 119
SER A 123
ILE A  94
PHE A  22
 None
 1.16A 2q72A-5wosA:
undetectable		 2q72A-5wosA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtk CRISPR-ASSOCIATED
ENDORIBONUCLEASE
C2C2

(Leptotrichia
shahii) 		no annotation 4 ILE A 874
ARG A 608
ARG A 599
ILE A 600
 None
 1.16A 2q72A-5wtkA:
undetectable		 2q72A-5wtkA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x1e ICMO (DOTL)
ICMW

(Legionella
pneumophila) 		no annotation 4 ILE C 767
ARG C 761
ILE B  73
PHE B  70
 None
 1.08A 2q72A-5x1eC:
undetectable		 2q72A-5x1eC:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x3t RIBONUCLEASE VAPC26

(Mycobacterium
tuberculosis) 		PF01850
(PIN) 		4 ILE B  84
ARG B 106
ILE B   2
PHE B 120
 None
 1.09A 2q72A-5x3tB:
undetectable		 2q72A-5x3tB:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3r PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		no annotation 4 ILE A2164
SER A2168
ARG A2169
ILE A2503
 None
 1.17A 2q72A-6b3rA:
1.7		 2q72A-6b3rA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE v 172
SER v  25
ILE v  50
PHE v 190
 None
 1.09A 2q72A-6c0fv:
undetectable		 2q72A-6c0fv:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cjb CYSTATHIONINE
BETA-LYASE

(Legionella
pneumophila) 		no annotation 4 ILE A 347
SER A 346
ARG A 106
PHE A 122
 None
 1.15A 2q72A-6cjbA:
undetectable		 2q72A-6cjbA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6v TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila) 		no annotation 4 ILE A 488
ARG A 473
ILE A 469
PHE A 408
 None
C  B  43 ( 4.0A)
None
None
 0.83A 2q72A-6d6vA:
undetectable		 2q72A-6d6vA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC2

(Saccharomyces
cerevisiae) 		no annotation 4 ILE B 613
ARG B 580
ARG B 579
PHE B 637
 None
 1.12A 2q72A-6f42B:
undetectable		 2q72A-6f42B:
9.63