SIMILAR PATTERNS OF AMINO ACIDS FOR 2Q6H_A_CXXA802_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bf5 SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind) 		4 ILE A 578
ARG A 602
PHE A 581
PHE A 506
 None
 1.09A 2q6hA-1bf5A:
0.0		 2q6hA-1bf5A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)

(Cupriavidus
necator) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 ILE A 124
ARG A  44
PHE A  43
ILE A  45
 None
 1.09A 2q6hA-1bxnA:
0.0		 2q6hA-1bxnA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE

(Hydrogenophaga
pseudoflava) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 ILE C 130
ARG C 171
PHE C 136
ILE C 170
 None
 1.15A 2q6hA-1ffvC:
0.2		 2q6hA-1ffvC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fs5 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Escherichia
coli) 		PF01182
(Glucosamine_iso) 		4 ILE A  20
PHE A  63
ILE A  99
PHE A  93
 None
 1.09A 2q6hA-1fs5A:
0.0		 2q6hA-1fs5A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyc LACCASE 2

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 238
ARG A 260
ILE A 213
PHE A 246
 None
 0.97A 2q6hA-1gycA:
undetectable		 2q6hA-1gycA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j26 IMMATURE COLON
CARCINOMA TRANSCRIPT
1

(Mus musculus) 		PF00472
(RF-1) 		4 ILE A  17
SER A  14
ILE A  64
PHE A  48
 None
 0.87A 2q6hA-1j26A:
undetectable		 2q6hA-1j26A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3u ASPARTASE

(Bacillus sp.
YM55-1) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 ILE A 291
ARG A 296
ILE A 309
PHE A 201
 None
 1.10A 2q6hA-1j3uA:
0.1		 2q6hA-1j3uA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella nova) 		PF07404
(TEBP_beta) 		4 ILE B  90
PHE B  63
ILE B  80
PHE B  50
 None
 1.07A 2q6hA-1jb7B:
undetectable		 2q6hA-1jb7B:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne7 GLUCOSAMINE-6-PHOSPH
ATE ISOMERASE

(Homo sapiens) 		PF01182
(Glucosamine_iso) 		4 ILE A  20
PHE A  63
ILE A  99
PHE A  93
 None
 1.06A 2q6hA-1ne7A:
0.0		 2q6hA-1ne7A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5t TRYPTOPHANYL-TRNA
SYNTHETASE

(Homo sapiens) 		PF00579
(tRNA-synt_1b) 		4 ILE A 359
PHE A 340
ILE A 175
PHE A 406
 None
 1.13A 2q6hA-1o5tA:
0.0		 2q6hA-1o5tA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6u TRYPTOPHANYL-TRNA
SYNTHETASE

(Homo sapiens) 		PF00579
(tRNA-synt_1b) 		4 ILE A 359
PHE A 340
ILE A 175
PHE A 406
 None
None
TYM  A 501 ( 4.5A)
None
 1.02A 2q6hA-1r6uA:
undetectable		 2q6hA-1r6uA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw2 ATP-DEPENDENT DNA
HELICASE II, 80 KDA
SUBUNIT

(Homo sapiens) 		PF08785
(Ku_PK_bind) 		4 ILE A  81
ARG A  96
PHE A  97
ILE A 128
 None
 1.03A 2q6hA-1rw2A:
undetectable		 2q6hA-1rw2A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpm ACYL-COA HYDROLASE

(Bacillus
halodurans) 		PF03061
(4HBT) 		4 ILE A  38
ARG A  16
ILE A  29
PHE A  64
 None
 1.03A 2q6hA-1vpmA:
undetectable		 2q6hA-1vpmA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w33 BBCRASP-1

(Borreliella
burgdorferi) 		PF05714
(Borrelia_lipo_1) 		4 ILE A 163
SER A 167
ILE A 139
PHE A 104
 None
 1.11A 2q6hA-1w33A:
undetectable		 2q6hA-1w33A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wzx COG3291: FOG: PKD
REPEAT

(Ruminiclostridium
thermocellum) 		no annotation 4 ILE A 123
PHE A 172
ILE A 175
PHE A 160
 None
 1.06A 2q6hA-1wzxA:
undetectable		 2q6hA-1wzxA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkt FATTY ACID SYNTHASE

(Homo sapiens) 		PF00975
(Thioesterase) 		4 ARG A2220
PHE A2375
ILE A2404
PHE A2371
 None
 1.15A 2q6hA-1xktA:
0.0		 2q6hA-1xktA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yz6 PROBABLE TRANSLATION
INITIATION FACTOR 2
ALPHA SUBUNIT

(Pyrococcus
abyssi) 		PF00575
(S1)
PF07541
(EIF_2_alpha) 		4 ILE A 251
ARG A 201
ILE A 243
PHE A 182
 None
 1.00A 2q6hA-1yz6A:
undetectable		 2q6hA-1yz6A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvt BETA-1,4-MANNANASE

(Cellulomonas
fimi) 		PF02156
(Glyco_hydro_26) 		4 ILE A 168
SER A 158
PHE A  94
ILE A  74
 None
 0.82A 2q6hA-2bvtA:
undetectable		 2q6hA-2bvtA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2det TRNA-SPECIFIC
2-THIOURIDYLASE MNMA

(Escherichia
coli) 		PF03054
(tRNA_Me_trans) 		4 SER A  21
ARG A 131
PHE A 168
PHE A 108
 None
 1.16A 2q6hA-2detA:
undetectable		 2q6hA-2detA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f91 HEPATOPANCREAS
TRYPSIN

(Astacus
leptodactylus) 		PF00089
(Trypsin) 		4 ILE A  88
SER A 104
PHE A  33
ILE A  66
 None
 1.05A 2q6hA-2f91A:
undetectable		 2q6hA-2f91A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fej CELLULAR TUMOR
ANTIGEN P53

(Homo sapiens) 		PF00870
(P53) 		4 ILE A 251
ARG A 158
ILE A 255
PHE A 270
 None
 1.06A 2q6hA-2fejA:
undetectable		 2q6hA-2fejA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fji EXOCYST COMPLEX
COMPONENT SEC6

(Saccharomyces
cerevisiae) 		PF06046
(Sec6) 		4 ILE 1 546
SER 1 549
PHE 1 652
ILE 1 601
 None
 1.09A 2q6hA-2fji1:
undetectable		 2q6hA-2fji1:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g2b ALLOGRAFT
INFLAMMATORY FACTOR
1

(Homo sapiens) 		no annotation 4 ILE A  68
ARG A  26
ILE A  30
PHE A  53
 None
 0.99A 2q6hA-2g2bA:
undetectable		 2q6hA-2g2bA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gaf POLY(A) POLYMERASE
CATALYTIC SUBUNIT

(Vaccinia virus) 		PF03296
(Pox_polyA_pol)
PF12629
(Pox_polyA_pol_C)
PF12630
(Pox_polyA_pol_N) 		4 ILE D 205
SER D 254
PHE D 213
ILE D 111
 None
 1.11A 2q6hA-2gafD:
undetectable		 2q6hA-2gafD:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gkd CALC

(Micromonospora
echinospora) 		no annotation 4 ILE A 140
ARG A  82
ILE A  79
PHE A  23
 None
 0.91A 2q6hA-2gkdA:
undetectable		 2q6hA-2gkdA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gtt NUCLEOPROTEIN

(Rabies
lyssavirus) 		PF00945
(Rhabdo_ncap) 		4 ARG A 270
PHE A 273
ILE A 269
PHE A 242
 None
 1.06A 2q6hA-2gttA:
undetectable		 2q6hA-2gttA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzh LACCASE

(Trametes
ochracea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 238
ARG A 260
ILE A 213
PHE A 246
 None
 0.98A 2q6hA-2hzhA:
undetectable		 2q6hA-2hzhA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7n PANTOTHENATE KINASE
1

(Homo sapiens) 		PF03630
(Fumble) 		4 ARG A 311
PHE A 312
ILE A 310
PHE A 320
 None
 1.09A 2q6hA-2i7nA:
undetectable		 2q6hA-2i7nA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7n PANTOTHENATE KINASE
1

(Homo sapiens) 		PF03630
(Fumble) 		4 ILE A 243
PHE A 312
ILE A 310
PHE A 320
 None
 1.07A 2q6hA-2i7nA:
undetectable		 2q6hA-2i7nA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m76 CARNITINE
O-PALMITOYLTRANSFERA
SE 1, BRAIN ISOFORM

(Homo sapiens) 		PF16484
(CPT_N) 		4 ILE A  31
SER A  34
ARG A  37
ARG A  41
 None
 1.05A 2q6hA-2m76A:
undetectable		 2q6hA-2m76A:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ock VALACYCLOVIR
HYDROLASE

(Homo sapiens) 		PF00561
(Abhydrolase_1) 		4 ARG A 197
PHE A 199
ILE A 196
PHE A  97
 None
 1.07A 2q6hA-2ockA:
undetectable		 2q6hA-2ockA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt6 LACCASE

(Lentinus
tigrinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 238
ARG A 260
ILE A 213
PHE A 246
 None
 0.92A 2q6hA-2qt6A:
undetectable		 2q6hA-2qt6A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0x POSSIBLE FLAVIN
REDUCTASE

(Histophilus
somni) 		PF01613
(Flavin_Reduct) 		4 SER A 105
ARG A  65
PHE A  61
PHE A  32
 None
EDO  A 167 (-4.1A)
None
None
 1.11A 2q6hA-2r0xA:
undetectable		 2q6hA-2r0xA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uz0 TRIBUTYRIN ESTERASE

(Streptococcus
pneumoniae) 		PF00756
(Esterase) 		4 ARG A 111
ARG A 135
ILE A 116
PHE A 243
 None
 1.04A 2q6hA-2uz0A:
undetectable		 2q6hA-2uz0A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v26 MYOSIN VI

(Sus scrofa) 		PF00063
(Myosin_head) 		4 SER A 150
ARG A 667
PHE A 665
ILE A 488
 None
 1.02A 2q6hA-2v26A:
2.3		 2q6hA-2v26A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5o CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Homo sapiens) 		PF00040
(fn2)
PF00878
(CIMR) 		4 ILE A1918
ARG A1615
ARG A1669
PHE A1905
 None
 0.91A 2q6hA-2v5oA:
undetectable		 2q6hA-2v5oA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7y CHAPERONE PROTEIN
DNAK

(Geobacillus
kaustophilus) 		PF00012
(HSP70) 		4 ILE A 370
ARG A 425
PHE A 426
ILE A 468
 None
 0.97A 2q6hA-2v7yA:
undetectable		 2q6hA-2v7yA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x25 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
A

(Homo sapiens) 		PF00160
(Pro_isomerase) 		4 SER B  40
PHE B 112
ILE B 114
PHE B  53
 None
 1.14A 2q6hA-2x25B:
undetectable		 2q6hA-2x25B:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsw 72 KDA INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		4 ILE A 421
SER A 423
ARG A 435
ILE A 519
 None
 0.80A 2q6hA-2xswA:
undetectable		 2q6hA-2xswA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 238
ARG A 260
ILE A 213
PHE A 246
 None
 0.99A 2q6hA-2xybA:
undetectable		 2q6hA-2xybA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5w PROBABLE
PEROXIREDOXIN

(Aeropyrum
pernix) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		4 ILE A 154
ARG A 232
ARG A  59
PHE A  40
 None
 1.10A 2q6hA-3a5wA:
undetectable		 2q6hA-3a5wA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF06405
(RCC_reductase) 		4 ILE A 135
SER A 137
ILE A 312
PHE A 296
 None
 1.13A 2q6hA-3agbA:
undetectable		 2q6hA-3agbA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c9b VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75

(Saccharomyces
cerevisiae) 		PF00956
(NAP) 		4 ILE A  80
PHE A 180
ILE A 146
PHE A 116
 None
 0.97A 2q6hA-3c9bA:
undetectable		 2q6hA-3c9bA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e1t HALOGENASE

(Chondromyces
crocatus) 		PF04820
(Trp_halogenase) 		4 ILE A 210
ARG A 206
PHE A  92
PHE A 312
 None
 0.85A 2q6hA-3e1tA:
undetectable		 2q6hA-3e1tA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e1t HALOGENASE

(Chondromyces
crocatus) 		PF04820
(Trp_halogenase) 		4 ILE A 210
SER A 212
PHE A  92
PHE A  94
 None
 1.06A 2q6hA-3e1tA:
undetectable		 2q6hA-3e1tA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3enh UNCHARACTERIZED
PROTEIN MJ0187

(Methanocaldococcus
jannaschii) 		PF08617
(CGI-121) 		4 ILE C 142
ARG C 123
PHE C 126
ILE C 122
 None
 0.71A 2q6hA-3enhC:
undetectable		 2q6hA-3enhC:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf6 UNCHARACTERIZED
BACTERIAL
LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12956
(DUF3845) 		4 ILE A 229
SER A 233
ARG A 137
PHE A 194
 None
None
EDO  A   2 (-4.1A)
None
 1.14A 2q6hA-3gf6A:
undetectable		 2q6hA-3gf6A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hqf RESTRICTION
ENDONUCLEASE

(Escherichia
coli) 		PF09217
(EcoRII-N) 		4 ILE A 136
ARG A  98
ILE A  42
PHE A 122
 None
 1.14A 2q6hA-3hqfA:
undetectable		 2q6hA-3hqfA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1

(Rattus
norvegicus) 		PF00520
(Ion_trans) 		4 ARG A 120
PHE A 116
ILE A 113
PHE A 137
 None
 0.89A 2q6hA-3j9jA:
undetectable		 2q6hA-3j9jA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7y ASPARTATE
AMINOTRANSFERASE

(Plasmodium
falciparum) 		PF00155
(Aminotran_1_2) 		4 ILE A 157
ARG A 380
ILE A 381
PHE A 329
 None
 1.04A 2q6hA-3k7yA:
undetectable		 2q6hA-3k7yA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksc LEGA CLASS

(Pisum sativum) 		PF00190
(Cupin_1) 		4 ILE A 326
ARG A 323
ILE A  70
PHE A 435
 None
GOL  A 499 (-3.3A)
None
None
 1.05A 2q6hA-3kscA:
undetectable		 2q6hA-3kscA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3llb UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF03471
(CorC_HlyC) 		4 ARG A  62
ARG A  64
PHE A  63
PHE A  22
 None
 1.02A 2q6hA-3llbA:
undetectable		 2q6hA-3llbA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lyc PUTATIVE PECTINASE

(Parabacteroides
distasonis) 		PF10988
(DUF2807) 		4 ILE A 158
PHE A 147
ILE A 126
PHE A 135
 None
 1.02A 2q6hA-3lycA:
undetectable		 2q6hA-3lycA:
19.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		7 ILE A 178
SER A 181
ARG A 185
ARG A 193
PHE A 194
ILE A 197
PHE A 350
 None
 0.27A 2q6hA-3mpnA:
68.1		 2q6hA-3mpnA:
99.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mr7 ADENYLATE/GUANYLATE
CYCLASE/HYDROLASE,
ALPHA/BETA FOLD
FAMILY

(Ruegeria
pomeroyi) 		PF00211
(Guanylate_cyc) 		4 ILE A 134
SER A 132
ARG A 119
ILE A 158
 None
 0.90A 2q6hA-3mr7A:
undetectable		 2q6hA-3mr7A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0z ADENYLATE CYCLASE 2

(Yersinia pestis) 		PF01928
(CYTH) 		4 ILE A  70
SER A  68
PHE A  35
PHE A   5
 3AT  A 181 ( 4.6A)
None
None
3AT  A 181 (-3.6A)
 0.93A 2q6hA-3n0zA:
undetectable		 2q6hA-3n0zA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxl LACCASE

(Trametes
hirsuta) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 238
ARG A 260
ILE A 213
PHE A 246
 None
 0.95A 2q6hA-3pxlA:
undetectable		 2q6hA-3pxlA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qg5 RAD50

(Thermotoga
maritima) 		PF13476
(AAA_23)
PF13558
(SbcCD_C) 		4 ILE A 811
PHE A 838
ILE A  25
PHE A 827
 None
 1.14A 2q6hA-3qg5A:
undetectable		 2q6hA-3qg5A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swj PUTATIVE
UNCHARACTERIZED
PROTEIN

(Campylobacter
jejuni) 		PF01243
(Putative_PNPOx)
PF10615
(DUF2470) 		4 ARG A 168
PHE A 151
ILE A 149
PHE A 119
 HEM  A 300 (-4.5A)
None
None
None
 1.02A 2q6hA-3swjA:
undetectable		 2q6hA-3swjA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 241
ARG A 263
ILE A 216
PHE A 249
 None
SO4  A 506 (-2.7A)
None
None
 0.94A 2q6hA-3t6wA:
undetectable		 2q6hA-3t6wA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlz MCCF

(Escherichia
coli) 		PF02016
(Peptidase_S66) 		4 ILE A 113
PHE A 159
ILE A 160
PHE A  48
 None
 1.08A 2q6hA-3tlzA:
undetectable		 2q6hA-3tlzA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsy FUSION PROTEIN
4-COUMARATE--COA
LIGASE 1,
RESVERATROL SYNTHASE

(Arabidopsis
thaliana;
Vitis vinifera) 		PF00195
(Chal_sti_synt_N)
PF00501
(AMP-binding)
PF02797
(Chal_sti_synt_C)
PF13193
(AMP-binding_C) 		4 ILE A  97
ARG A 202
PHE A 203
ILE A 188
 None
 1.10A 2q6hA-3tsyA:
undetectable		 2q6hA-3tsyA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujh GLUCOSE-6-PHOSPHATE
ISOMERASE

(Toxoplasma
gondii) 		PF00342
(PGI) 		4 ILE A 151
ARG A 266
PHE A 247
ILE A 262
 None
 1.12A 2q6hA-3ujhA:
0.8		 2q6hA-3ujhA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1b LACCASE

(Lentinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 259
ARG A 281
ILE A 234
PHE A 267
 None
 1.02A 2q6hA-3x1bA:
undetectable		 2q6hA-3x1bA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zv8 3C PROTEASE

(Enterovirus D) 		PF00548
(Peptidase_C3) 		4 ILE A 158
ARG A  87
ILE A  86
PHE A   6
 None
 1.14A 2q6hA-3zv8A:
undetectable		 2q6hA-3zv8A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF13306
(LRR_5) 		4 ILE A 219
PHE A 261
ILE A 257
PHE A 235
 None
 0.74A 2q6hA-4fs7A:
undetectable		 2q6hA-4fs7A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gtn ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Acinetobacter
sp. ADP1) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 ILE A 308
SER A 306
ILE A 316
PHE A 111
 None
 1.14A 2q6hA-4gtnA:
undetectable		 2q6hA-4gtnA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hiz ENDOSIALIDASE

(Enterobacteria
phage phi92) 		PF12217
(End_beta_propel)
PF12218
(End_N_terminal)
PF12219
(End_tail_spike) 		4 ILE A 425
SER A 367
PHE A 474
ILE A 483
 None
 1.11A 2q6hA-4hizA:
undetectable		 2q6hA-4hizA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i70 INOSINE-ADENOSINE-GU
ANOSINE-NUCLEOSIDE
HYDROLASE

(Trypanosoma
brucei) 		PF01156
(IU_nuc_hydro) 		4 ILE A   6
ARG A 204
ILE A 203
PHE A 154
 None
 1.06A 2q6hA-4i70A:
undetectable		 2q6hA-4i70A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhv LACCASE

(Coriolopsis
caperata) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 237
ARG A 259
ILE A 212
PHE A 245
 None
 0.97A 2q6hA-4jhvA:
undetectable		 2q6hA-4jhvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ky9 BAND 3 ANION
TRANSPORT PROTEIN

(Homo sapiens) 		PF07565
(Band_3_cyto) 		4 SER A 310
ARG A 111
PHE A 114
PHE A 266
 None
 1.13A 2q6hA-4ky9A:
undetectable		 2q6hA-4ky9A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiq D-XYLOSE-PROTON
SYMPORTER

(Escherichia
coli) 		PF00083
(Sugar_tr) 		4 ILE A 280
ARG A 404
PHE A 399
ILE A 398
 None
 1.16A 2q6hA-4qiqA:
0.0		 2q6hA-4qiqA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE

(Thermococcus
kodakarensis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 SER B 100
ARG B 122
ILE B 123
PHE B 359
 None
 1.13A 2q6hA-4qiwB:
undetectable		 2q6hA-4qiwB:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0k DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
thetaiotaomicron) 		PF00877
(NLPC_P60) 		4 ILE A 234
ARG A 272
PHE A 285
PHE A 249
 None
 0.99A 2q6hA-4r0kA:
undetectable		 2q6hA-4r0kA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ttw CENTRIOLE PROTEIN

(Chlamydomonas
reinhardtii) 		PF16531
(SAS-6_N) 		4 ILE A 106
ARG A  27
PHE A  47
PHE A 137
 None
 1.10A 2q6hA-4ttwA:
undetectable		 2q6hA-4ttwA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E

(Rattus
norvegicus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 ILE A 104
SER A 107
ILE A 138
PHE A 142
 None
 0.98A 2q6hA-4yswA:
undetectable		 2q6hA-4yswA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zht BIFUNCTIONAL
UDP-N-ACETYLGLUCOSAM
INE
2-EPIMERASE/N-ACETYL
MANNOSAMINE KINASE

(Homo sapiens) 		PF02350
(Epimerase_2) 		4 ILE A 254
ARG A  77
ILE A  75
PHE A 114
 None
 1.04A 2q6hA-4zhtA:
undetectable		 2q6hA-4zhtA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 SER A 293
PHE A 477
ILE A 495
PHE A 491
 None
 1.01A 2q6hA-5bnzA:
undetectable		 2q6hA-5bnzA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bv8 VON WILLEBRAND
FACTOR

(Homo sapiens) 		PF00092
(VWA)
PF16164
(VWA_N2) 		4 ILE A1309
ARG A1374
ARG A1379
PHE A1280
 None
 1.12A 2q6hA-5bv8A:
undetectable		 2q6hA-5bv8A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cb2 PROTEIN SEY1

(Candida
albicans) 		PF05879
(RHD3) 		4 ILE A  60
SER A  62
PHE A 145
ILE A  32
 None
 1.02A 2q6hA-5cb2A:
undetectable		 2q6hA-5cb2A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B

(Neotoma lepida) 		PF00067
(p450) 		4 SER A 160
PHE A 157
ILE A 453
PHE A 171
 None
 1.14A 2q6hA-5e0eA:
undetectable		 2q6hA-5e0eA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 239
ARG A 261
ILE A 214
PHE A 247
 None
 0.95A 2q6hA-5ehfA:
undetectable		 2q6hA-5ehfA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8g ANTIFREEZE PROTEIN

(Marinomonas
primoryensis) 		no annotation 4 ILE A 364
ARG A 368
PHE A 367
PHE A 326
 None
 0.86A 2q6hA-5k8gA:
undetectable		 2q6hA-5k8gA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbd TUMOR PROTEIN P73

(Homo sapiens) 		PF00870
(P53) 		4 ILE A 271
ARG A 176
ILE A 275
PHE A 290
 None
 1.16A 2q6hA-5kbdA:
undetectable		 2q6hA-5kbdA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lmg DNA TOPOISOMERASE
2-ASSOCIATED PROTEIN
PAT1

(Saccharomyces
cerevisiae) 		PF09770
(PAT1) 		4 ILE A 565
SER A 568
PHE A 587
ILE A 533
 None
 1.12A 2q6hA-5lmgA:
1.0		 2q6hA-5lmgA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 241
ARG A 263
ILE A 216
PHE A 249
 None
 1.02A 2q6hA-5mewA:
undetectable		 2q6hA-5mewA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr HETERODISULFIDE
REDUCTASE, SUBUNIT A

(Methanothermococcus
thermolithotrophicus) 		PF07992
(Pyr_redox_2)
PF13187
(Fer4_9) 		4 SER A 492
ARG A 431
ILE A 430
PHE A 452
 None
SF4  A 702 (-4.5A)
None
GOL  A 709 (-4.4A)
 1.09A 2q6hA-5odrA:
undetectable		 2q6hA-5odrA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oom 39S RIBOSOMAL
PROTEIN L43,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 ILE b  63
ARG b  74
ILE b  89
PHE b  46
 None
C  A2284 ( 3.3A)
None
None
 0.85A 2q6hA-5oomb:
undetectable		 2q6hA-5oomb:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5suj UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		no annotation 4 ILE A 134
ARG A 338
ILE A 138
PHE A 246
 None
 0.99A 2q6hA-5sujA:
undetectable		 2q6hA-5sujA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u81 ACID CERAMIDASE
ISOFORM B

(Heterocephalus
glaber) 		no annotation 4 ILE A 294
SER A 301
ARG A 298
ILE A 249
 None
 1.16A 2q6hA-5u81A:
undetectable		 2q6hA-5u81A:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ufl PROTEIN CIP2A

(Homo sapiens) 		no annotation 4 ILE A 393
PHE A 370
ILE A 369
PHE A 385
 None
 0.93A 2q6hA-5uflA:
undetectable		 2q6hA-5uflA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um6 UBIQUITIN-ACTIVATING
ENZYME E1 1

(Schizosaccharomyces
pombe) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		4 ILE A 602
SER A 827
ARG A 610
ILE A 851
 None
 1.13A 2q6hA-5um6A:
1.3		 2q6hA-5um6A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqz GLUCAN-BINDING
PROTEIN C, GBPC

(Streptococcus
mutans) 		no annotation 4 ILE A 277
PHE A 326
ILE A 272
PHE A 189
 None
 1.16A 2q6hA-5uqzA:
undetectable		 2q6hA-5uqzA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vlj NUCLEAR DISTRIBUTION
PROTEIN PAC1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 ILE B 340
SER B 302
ILE B 387
PHE B 407
 None
 0.92A 2q6hA-5vljB:
undetectable		 2q6hA-5vljB:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x3t RIBONUCLEASE VAPC26

(Mycobacterium
tuberculosis) 		PF01850
(PIN) 		4 ILE B  84
ARG B 106
ILE B   2
PHE B 120
 None
 1.08A 2q6hA-5x3tB:
undetectable		 2q6hA-5x3tB:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xop CALCIUM-BINDING
PROTEIN 1 (EHCBP1),
PUTATIVE

(Entamoeba
histolytica) 		no annotation 4 ILE A  41
SER A  44
PHE A  61
ILE A  65
 None
 0.86A 2q6hA-5xopA:
undetectable		 2q6hA-5xopA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y30 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 4 ILE A  61
PHE A  98
ILE A 122
PHE A 111
 None
 0.97A 2q6hA-5y30A:
undetectable		 2q6hA-5y30A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 4 ILE B  61
PHE B  98
ILE B 122
PHE B 111
 None
 0.95A 2q6hA-5y31B:
undetectable		 2q6hA-5y31B:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4m MONOTREME LACTATION
PROTEIN

(Ornithorhynchus
anatinus) 		no annotation 4 ILE A  51
ARG A  61
PHE A 141
PHE A 150
 None
 1.13A 2q6hA-6b4mA:
0.6		 2q6hA-6b4mA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 709
SER A 662
PHE A 734
PHE A 744
 None
 1.11A 2q6hA-6eojA:
undetectable		 2q6hA-6eojA:
16.96