SIMILAR PATTERNS OF AMINO ACIDS FOR 2PO5_A_CHDA502_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bev | BOVINE ENTEROVIRUSCOAT PROTEINS VP1 TOVP4 (Enterovirus E) |
PF00073(Rhv) | 4 | LEU 3 165LEU 3 94PRO 3 141GLY 3 192 | None | 0.97A | 2po5A-1bev3:undetectable | 2po5A-1bev3:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f2n | CAPSID PROTEIN (Rice yellowmottle virus) |
PF00729(Viral_coat) | 4 | MET A 226LEU A 228ARG A 93PRO A 200 | None | 0.88A | 2po5A-1f2nA:undetectable | 2po5A-1f2nA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lns | X-PROLYL DIPEPTIDYLAMINOPEPTIDASE (Lactococcuslactis) |
PF02129(Peptidase_S15)PF08530(PepX_C)PF09168(PepX_N) | 4 | LEU A 398PRO A 209VAL A 290GLY A 291 | None | 0.85A | 2po5A-1lnsA:1.8 | 2po5A-1lnsA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqt | POLYPROTEIN CAPSIDPROTEIN (Enterovirus B) |
PF00073(Rhv) | 4 | LEU C 166LEU C 95PRO C 142GLY C 188 | None | 0.91A | 2po5A-1mqtC:undetectable | 2po5A-1mqtC:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n47 | ISOLECTIN B4 (Vicia villosa) |
PF00139(Lectin_legB) | 4 | MET A 75LEU A 105PRO A 42GLY A 212 | NoneNoneNoneTNR A1401 ( 3.7A) | 0.99A | 2po5A-1n47A:undetectable | 2po5A-1n47A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oyw | ATP-DEPENDENT DNAHELICASE (Escherichiacoli) |
PF00270(DEAD)PF00271(Helicase_C)PF09382(RQC)PF16124(RecQ_Zn_bind) | 4 | MET A 127LEU A 132ARG A 169VAL A 145 | None | 0.77A | 2po5A-1oywA:3.6 | 2po5A-1oywA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p0z | SENSOR KINASE CITA (Klebsiellapneumoniae) |
PF17203(sCache_3_2) | 4 | LEU A 132ARG A 15VAL A 95GLY A 108 | MO7 A1630 ( 4.3A)NoneNoneNone | 0.97A | 2po5A-1p0zA:undetectable | 2po5A-1p0zA:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p31 | UDP-N-ACETYLMURAMATE--ALANINE LIGASE (Haemophilusinfluenzae) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | LEU A 184ARG A 118GLY A 33MET A 31 | NoneNoneNoneEPU A 598 (-4.5A) | 0.75A | 2po5A-1p31A:2.7 | 2po5A-1p31A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1unn | DNA POLYMERASE IV (Escherichiacoli) |
PF11799(IMS_C) | 4 | LEU C 281LEU C 312VAL C 245GLY C 244 | None | 0.90A | 2po5A-1unnC:undetectable | 2po5A-1unnC:15.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1we5 | PUTATIVE FAMILY 31GLUCOSIDASE YICI (Escherichiacoli) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 4 | LEU A 123LEU A 154VAL A 67GLY A 66 | None | 0.70A | 2po5A-1we5A:undetectable | 2po5A-1we5A:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wuu | GALACTOKINASE (Homo sapiens) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | LEU A 206ARG A 166PRO A 54GLY A 193 | None | 0.97A | 2po5A-1wuuA:undetectable | 2po5A-1wuuA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wwl | MONOCYTEDIFFERENTIATIONANTIGEN CD14 (Mus musculus) |
no annotation | 4 | LEU A 267LEU A 260VAL A 221GLY A 220 | None | 0.78A | 2po5A-1wwlA:undetectable | 2po5A-1wwlA:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wzz | PROBABLEENDOGLUCANASE (Komagataeibacterxylinus) |
PF01270(Glyco_hydro_8) | 4 | MET A 78LEU A 39LEU A 330GLY A 70 | None | 0.93A | 2po5A-1wzzA:undetectable | 2po5A-1wzzA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b2a | TELOMERASE REVERSETRANSCRIPTASE (Tetrahymenathermophila) |
PF11474(N-Term_TEN) | 4 | LEU A 71LEU A 30VAL A 172GLY A 171 | None | 0.84A | 2po5A-2b2aA:undetectable | 2po5A-2b2aA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bvg | 6-HYDROXY-D-NICOTINEOXIDASE (Paenarthrobacternicotinovorans) |
PF01565(FAD_binding_4)PF08031(BBE) | 4 | LEU A 231LEU A 399PRO A 218GLY A 248 | None | 0.91A | 2po5A-2bvgA:undetectable | 2po5A-2bvgA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dy3 | ALANINE RACEMASE (Corynebacteriumglutamicum) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | LEU A 29ARG A 18PRO A 224GLY A 221 | None | 0.84A | 2po5A-2dy3A:undetectable | 2po5A-2dy3A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f00 | UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (Escherichiacoli) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | LEU A 185ARG A 119GLY A 34MET A 32 | None | 0.77A | 2po5A-2f00A:3.3 | 2po5A-2f00A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fz5 | FLAVODOXIN (Megasphaeraelsdenii) |
PF00258(Flavodoxin_1) | 4 | LEU A 62LEU A 74VAL A 83GLY A 84 | None | 0.90A | 2po5A-2fz5A:2.9 | 2po5A-2fz5A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gid | MITOCHONDRIALRNA-BINDING PROTEIN1 (Trypanosomabrucei) |
PF09387(MRP) | 4 | LEU B 88LEU B 154VAL B 99GLY B 98 | None | 0.94A | 2po5A-2gidB:undetectable | 2po5A-2gidB:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hiv | THERMOSTABLE DNALIGASE (Sulfolobussolfataricus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | LEU A 207LEU A 26VAL A 172GLY A 173 | None | 0.96A | 2po5A-2hivA:undetectable | 2po5A-2hivA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hjg | GTP-BINDING PROTEINENGA (Bacillussubtilis) |
PF01926(MMR_HSR1)PF14714(KH_dom-like) | 4 | LEU A 55ARG A 22LEU A 152GLY A 15 | NoneNoneNoneGDP A 800 (-3.1A) | 1.01A | 2po5A-2hjgA:4.8 | 2po5A-2hjgA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hor | ALLIIN LYASE 1 (Allium sativum) |
PF04863(EGF_alliinase)PF04864(Alliinase_C) | 4 | LEU A 297LEU A 264PRO A 231GLY A 117 | None | 1.01A | 2po5A-2horA:undetectable | 2po5A-2horA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hxo | PUTATIVE TETR-FAMILYTRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
PF00440(TetR_N)PF02909(TetR_C) | 4 | MET A 153LEU A 157VAL A 75GLY A 96 | None | 0.96A | 2po5A-2hxoA:undetectable | 2po5A-2hxoA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jh9 | VP4 CORE PROTEIN (Bluetonguevirus) |
PF05059(Orbi_VP4) | 4 | LEU A 78LEU A 28PRO A 493VAL A 7 | None | 0.89A | 2po5A-2jh9A:2.6 | 2po5A-2jh9A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lb5 | SENSOR HISTIDINEKINASE (Synechococcussp.JA-2-3B'a(2-13)) |
PF01590(GAF) | 4 | LEU A 181LEU A 166PRO A 173GLY A 47 | None | 0.98A | 2po5A-2lb5A:undetectable | 2po5A-2lb5A:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2no5 | (S)-2-HALOACIDDEHALOGENASE IVA (Burkholderiacepacia) |
PF13419(HAD_2) | 4 | LEU A 219ARG A 194LEU A 182GLY A 14 | NoneNoneNoneASL A 11 ( 4.2A) | 0.88A | 2po5A-2no5A:2.8 | 2po5A-2no5A:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nzt | HEXOKINASE-2 (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 4 | LEU A 427VAL A 412GLY A 411MET A 214 | None | 0.85A | 2po5A-2nztA:2.2 | 2po5A-2nztA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o1x | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE (Deinococcusradiodurans) |
PF02779(Transket_pyr)PF02780(Transketolase_C)PF13292(DXP_synthase_N) | 4 | LEU A 367VAL A 191GLY A 192MET A 194 | None | 0.98A | 2po5A-2o1xA:5.1 | 2po5A-2o1xA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1f | CHONDROITINASE (Bacteroidesthetaiotaomicron) |
PF02278(Lyase_8)PF09092(Lyase_N)PF09093(Lyase_catalyt) | 4 | LEU A 640ARG A 514PRO A 658GLY A 520 | None | 0.68A | 2po5A-2q1fA:undetectable | 2po5A-2q1fA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vla | RESTRICTIONENDONUCLEASE R.BPUJI (Bacilluspumilus) |
PF11564(BpuJI_N) | 4 | LEU A 232LEU A 214PRO A 177VAL A 164 | None | 0.98A | 2po5A-2vlaA:undetectable | 2po5A-2vlaA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3p | BENZOYL-COA-DIHYDRODIOL LYASE (Paraburkholderiaxenovorans) |
PF00378(ECH_1) | 4 | ARG A 311LEU A 307PRO A 243GLY A 248 | None | 0.83A | 2po5A-2w3pA:undetectable | 2po5A-2w3pA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfb | E1 ENVELOPEGLYCOPROTEIN (Chikungunyavirus) |
PF01589(Alpha_E1_glycop) | 4 | LEU A 38LEU A 33VAL A 163GLY A 164 | None | 0.98A | 2po5A-2xfbA:undetectable | 2po5A-2xfbA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y8n | 4-HYDROXYPHENYLACETATE DECARBOXYLASELARGE SUBUNIT (Clostridiumscatologenes) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | LEU A 424LEU A 232PRO A 440GLY A 349 | None | 0.94A | 2po5A-2y8nA:undetectable | 2po5A-2y8nA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yq1 | ORF73 (Muridgammaherpesvirus4) |
no annotation | 4 | MET A 146LEU A 150LEU A 217VAL A 245 | None | 0.88A | 2po5A-2yq1A:undetectable | 2po5A-2yq1A:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yr5 | PRO-ENZYME OFL-PHENYLALANINEOXIDASE (Pseudomonas sp.P-501) |
no annotation | 4 | MET A 327LEU A 269PRO A 232GLY A 211 | None | 0.88A | 2po5A-2yr5A:undetectable | 2po5A-2yr5A:18.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3aqi | FERROCHELATASE (Homo sapiens) |
PF00762(Ferrochelatase) | 8 | MET A 99LEU A 101ARG A 114LEU A 115PRO A 266VAL A 305GLY A 306MET A 308 | CHD A 2 (-4.0A)CHD A 3 ( 4.9A)CHD A 2 (-3.6A)CHD A 2 ( 4.8A)CHD A 2 ( 4.5A)CHD A 1 ( 4.9A)CHD A 2 ( 3.8A)None | 0.51A | 2po5A-3aqiA:60.6 | 2po5A-3aqiA:99.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aup | BASIC 7S GLOBULIN (Glycine max) |
PF14541(TAXi_C)PF14543(TAXi_N) | 4 | LEU A 168PRO A 152VAL A 38GLY A 157 | None | 0.92A | 2po5A-3aupA:undetectable | 2po5A-3aupA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwn | L-TRYPTOPHANAMINOTRANSFERASE (Arabidopsisthaliana) |
PF04864(Alliinase_C) | 4 | LEU A 263LEU A 230PRO A 197GLY A 85 | None | 1.01A | 2po5A-3bwnA:undetectable | 2po5A-3bwnA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c37 | PEPTIDASE, M48FAMILY (Geobactersulfurreducens) |
PF01435(Peptidase_M48) | 4 | LEU A 210ARG A 217VAL A 170GLY A 169 | None | 0.85A | 2po5A-3c37A:undetectable | 2po5A-3c37A:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ecd | SERINEHYDROXYMETHYLTRANSFERASE 2 (Burkholderiapseudomallei) |
PF00464(SHMT) | 4 | ARG A 366LEU A 321PRO A 221GLY A 178 | None | 0.79A | 2po5A-3ecdA:undetectable | 2po5A-3ecdA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f2a | PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE PIM-1 (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU A 228ARG A 156VAL A 103GLY A 102 | None | 0.89A | 2po5A-3f2aA:undetectable | 2po5A-3f2aA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrd | NICOTINATEDEHYDROGENASE MEDIUMMOLYBDOPTERINSUBUNIT (Eubacteriumbarkeri) |
PF02738(Ald_Xan_dh_C2) | 4 | LEU B 272PRO B 294VAL B 228GLY B 227 | None | 0.87A | 2po5A-3hrdB:undetectable | 2po5A-3hrdB:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kfu | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT AASPARTYL/GLUTAMYL-TRNA(ASN/GLN)AMIDOTRANSFERASESUBUNIT B (Thermusthermophilus;Thermusthermophilus) |
PF01425(Amidase)PF02637(GatB_Yqey)PF02934(GatB_N) | 4 | LEU E 111LEU E 306PRO E 88GLY F 46 | None | 0.86A | 2po5A-3kfuE:undetectable | 2po5A-3kfuE:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kve | L-AMINO ACID OXIDASE (Viperaammodytes) |
PF01593(Amino_oxidase) | 4 | LEU A 316ARG A 301VAL A 39GLY A 40 | NoneNoneFAD A 487 ( 4.6A)FAD A 487 (-3.3A) | 0.85A | 2po5A-3kveA:undetectable | 2po5A-3kveA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mv3 | COATOMER SUBUNITALPHA (Saccharomycescerevisiae) |
PF06957(COPI_C) | 4 | LEU A1038LEU A1022VAL A 933GLY A 932 | None | 0.96A | 2po5A-3mv3A:undetectable | 2po5A-3mv3A:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mx9 | PROTEIN SCV3V2(G19S) (Chlamydomonasreinhardtii) |
PF00961(LAGLIDADG_1) | 4 | LEU A 58ARG A 51LEU A 288GLY A 19 | NoneNoneNone CA A 364 (-4.1A) | 1.01A | 2po5A-3mx9A:undetectable | 2po5A-3mx9A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nbu | GLUCOSE-6-PHOSPHATEISOMERASE (Escherichiacoli) |
PF00342(PGI) | 4 | LEU A 66LEU A 500PRO A 400GLY A 329 | None | 0.96A | 2po5A-3nbuA:2.2 | 2po5A-3nbuA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qp9 | TYPE I POLYKETIDESYNTHASE PIKAII (Streptomycesvenezuelae) |
PF08659(KR) | 4 | LEU A 303LEU A 363VAL A 316GLY A 315 | None | 0.92A | 2po5A-3qp9A:3.1 | 2po5A-3qp9A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swg | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Aquifexaeolicus) |
PF00275(EPSP_synthase) | 4 | LEU A 366LEU A 295VAL A 247GLY A 248 | None | 0.84A | 2po5A-3swgA:undetectable | 2po5A-3swgA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tcs | RACEMASE, PUTATIVE (Roseobacterdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 63LEU A 3VAL A 17GLY A 29 | None | 0.82A | 2po5A-3tcsA:undetectable | 2po5A-3tcsA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u02 | PUTATIVETRANSCRIPTION-ASSOCIATED PROTEIN TFIIS (Pyrococcusfuriosus) |
PF08489(DUF1743) | 4 | LEU A 44LEU A 106VAL A 96GLY A 6 | None | 0.87A | 2po5A-3u02A:undetectable | 2po5A-3u02A:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u37 | ACETYL-XYLANESTERASE EST2A (Butyrivibrioproteoclasticus) |
PF13472(Lipase_GDSL_2) | 4 | LEU A 77LEU A 86VAL A 39GLY A 38 | None | 1.01A | 2po5A-3u37A:3.3 | 2po5A-3u37A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4f | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Roseovariusnubinhibens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 63LEU A 3VAL A 17GLY A 29 | None | 0.79A | 2po5A-3u4fA:undetectable | 2po5A-3u4fA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubc | HEMOGLOBIN-LIKEFLAVOPROTEIN (Methylacidiphiluminfernorum) |
PF00042(Globin) | 4 | MET A 130LEU A 54VAL A 95GLY A 96 | HEM A 201 ( 3.7A)OXY A 202 ( 4.3A)HEM A 201 (-4.1A)None | 0.62A | 2po5A-3ubcA:undetectable | 2po5A-3ubcA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v64 | LOW-DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 4 (Rattusnorvegicus) |
PF00058(Ldl_recept_b)PF14670(FXa_inhibition) | 4 | ARG C 479LEU C 481VAL C 505GLY C 542 | None | 0.89A | 2po5A-3v64C:undetectable | 2po5A-3v64C:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vvj | OVALBUMIN (Dromaiusnovaehollandiae) |
PF00079(Serpin) | 4 | MET A 54LEU A 306LEU A 175GLY A 315 | None | 0.98A | 2po5A-3vvjA:undetectable | 2po5A-3vvjA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3r | ENOLASE (Bacillussubtilis) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 189LEU A 219VAL A 160GLY A 152 | None | 0.96A | 2po5A-4a3rA:undetectable | 2po5A-4a3rA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ak5 | ANHYDRO-ALPHA-L-GALACTOSIDASE (Bacteroidesplebeius) |
PF04616(Glyco_hydro_43) | 4 | ARG A 383LEU A 76PRO A 166VAL A 103 | None | 1.00A | 2po5A-4ak5A:undetectable | 2po5A-4ak5A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bht | NADP-SPECIFICGLUTAMATEDEHYDROGENASE (Escherichiacoli) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | LEU A 106LEU A 150VAL A 171GLY A 167 | None | 0.94A | 2po5A-4bhtA:2.8 | 2po5A-4bhtA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d72 | GLYCOSIDE HYDROLASE (Streptococcuspneumoniae) |
PF08306(Glyco_hydro_98M)PF08307(Glyco_hydro_98C) | 4 | LEU A 692LEU A 685PRO A 438GLY A 717 | None | 0.81A | 2po5A-4d72A:undetectable | 2po5A-4d72A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4i | 4-O-METHYL-GLUCURONOYL METHYLESTERASE (Thermothelomycesthermophila) |
no annotation | 4 | LEU A 74ARG A 67GLY A 323MET A 320 | None | 1.00A | 2po5A-4g4iA:undetectable | 2po5A-4g4iA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j35 | PHOSPHOTRIESTERASE,PUTATIVE (Deinococcusradiodurans) |
PF02126(PTE) | 4 | LEU A 247LEU A 218PRO A 20GLY A 203 | None | 0.84A | 2po5A-4j35A:undetectable | 2po5A-4j35A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k5u | VARIABLE LYMPHOCYTERECEPTOR (Petromyzonmarinus) |
no annotation | 4 | LEU B 97LEU B 59VAL B 49GLY B 48 | None | 0.93A | 2po5A-4k5uB:undetectable | 2po5A-4k5uB:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p2f | ADENYLATE CYCLASE (Mycobacteriumtuberculosis) |
PF00211(Guanylate_cyc) | 4 | LEU A 396VAL A 345GLY A 346MET A 377 | NoneNoneNoneEDO A 510 ( 4.7A) | 0.99A | 2po5A-4p2fA:undetectable | 2po5A-4p2fA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ql9 | ALKYLHYDROPEROXIDEREDUCTASE SUBUNIT C (Escherichiacoli) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | LEU A 149PRO A 127VAL A 66GLY A 65 | None | 0.94A | 2po5A-4ql9A:2.3 | 2po5A-4ql9A:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uzu | ALPHA-AMYLASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 4 | LEU A 202PRO A 45VAL A 59GLY A 58 | None | 1.00A | 2po5A-4uzuA:undetectable | 2po5A-4uzuA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xyb | FORMATEDEHYDROGENASE (Granulicellamallensis) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | ARG A 164LEU A 160VAL A 216GLY A 192 | None | 0.97A | 2po5A-4xybA:4.5 | 2po5A-4xybA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5any | E1 (Chikungunyavirus) |
PF01589(Alpha_E1_glycop) | 4 | LEU A 38LEU A 33VAL A 163GLY A 164 | None | 0.93A | 2po5A-5anyA:undetectable | 2po5A-5anyA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5u | L-ASPARAGINASE (Pyrococcusfuriosus) |
no annotation | 4 | LEU B 280VAL B 268GLY B 288MET B 290 | None | 0.90A | 2po5A-5b5uB:undetectable | 2po5A-5b5uB:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7z | UNCHARACTERIZEDPROTEIN TM_0416 (Thermotogamaritima) |
PF01261(AP_endonuc_2) | 4 | LEU A 137ARG A 115PRO A 45GLY A 68 | NoneNoneMPD A 302 ( 4.8A)None | 0.81A | 2po5A-5b7zA:undetectable | 2po5A-5b7zA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5btb | AFR263CP (Eremotheciumgossypii) |
PF08652(RAI1) | 4 | LEU A 260LEU A 315VAL A 205GLY A 204 | None | 0.96A | 2po5A-5btbA:undetectable | 2po5A-5btbA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bz3 | NA(+)/H(+)ANTIPORTER (Thermusthermophilus) |
PF00999(Na_H_Exchanger) | 4 | LEU A 365PRO A 44VAL A 40GLY A 39 | None | 0.79A | 2po5A-5bz3A:undetectable | 2po5A-5bz3A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d19 | TETR FAMILYTRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N)PF13977(TetR_C_6) | 4 | LEU A 199LEU A 98VAL A 175GLY A 174 | None | 0.93A | 2po5A-5d19A:undetectable | 2po5A-5d19A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d39 | SIGNAL TRANSDUCERAND ACTIVATOR OFTRANSCRIPTION 6 (Homo sapiens) |
PF00017(SH2)PF01017(STAT_alpha)PF02864(STAT_bind) | 4 | LEU A 507LEU A 477VAL A 521GLY A 520 | None | 1.02A | 2po5A-5d39A:undetectable | 2po5A-5d39A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7t | MINOR STRUCTURALPROTEIN 5 (Lactococcusphage Tuc2009) |
no annotation | 4 | MET B 58LEU B 69VAL B 177GLY B 54 | None | 0.82A | 2po5A-5e7tB:undetectable | 2po5A-5e7tB:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fn4 | GAMMA-SECRETASESUBUNIT APH-1A (Homo sapiens) |
PF06105(Aph-1) | 4 | LEU C 35LEU C 43VAL C 131GLY C 130 | None | 1.01A | 2po5A-5fn4C:undetectable | 2po5A-5fn4C:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hlb | PENICILLIN-BINDINGPROTEIN 1B (Escherichiacoli) |
PF00905(Transpeptidase)PF00912(Transgly)PF14814(UB2H) | 4 | LEU A 394LEU A 342VAL A 401GLY A 400 | None | 0.93A | 2po5A-5hlbA:undetectable | 2po5A-5hlbA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i3a | TYROSINASE (Bacillusmegaterium) |
PF00264(Tyrosinase) | 4 | LEU A 172LEU A 66PRO A 163GLY A 196 | None | 0.92A | 2po5A-5i3aA:undetectable | 2po5A-5i3aA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5im3 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (Pseudomonasaeruginosa) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 4 | LEU A 467PRO A 506VAL A 426GLY A 425 | None | 0.99A | 2po5A-5im3A:undetectable | 2po5A-5im3A:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j04 | ENOLASE (Synechococcuselongatus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 193LEU A 223VAL A 164GLY A 156 | None | 0.98A | 2po5A-5j04A:undetectable | 2po5A-5j04A:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ko3 | ORF1A (Middle Eastrespiratorysyndrome-relatedcoronavirus) |
PF08715(Viral_protease) | 4 | LEU A 201LEU A 244VAL A 212GLY A 211 | None | 0.99A | 2po5A-5ko3A:undetectable | 2po5A-5ko3A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2x | DNA-DIRECTEDPRIMASE/POLYMERASEPROTEIN (Homo sapiens) |
no annotation | 4 | LEU A 134LEU A 142VAL A 185GLY A 186 | None | 1.00A | 2po5A-5l2xA:undetectable | 2po5A-5l2xA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lxg | ADIPONECTIN RECEPTORPROTEIN 1 (Homo sapiens) |
PF03006(HlyIII) | 4 | LEU A 365VAL A 297GLY A 298MET A 300 | None | 0.89A | 2po5A-5lxgA:undetectable | 2po5A-5lxgA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | LEU A 337LEU A 221PRO A 328GLY A 361 | None | 0.92A | 2po5A-5m8tA:undetectable | 2po5A-5m8tA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ocs | PUTATIVENADH-DEPENTDENTFLAVINOXIDOREDUCTASE (Cupriavidusmetallidurans) |
PF00724(Oxidored_FMN) | 4 | LEU A 71VAL A 89GLY A 43MET A 45 | None | 1.02A | 2po5A-5ocsA:undetectable | 2po5A-5ocsA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ot0 | L-ASPARAGINASE (Thermococcuskodakarensis) |
no annotation | 4 | LEU A 281VAL A 269GLY A 289MET A 291 | None | 0.89A | 2po5A-5ot0A:4.9 | 2po5A-5ot0A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ov6 | PORPHOBILINOGENDEAMINASE (Bacillusmegaterium) |
PF01379(Porphobil_deam)PF03900(Porphobil_deamC) | 4 | LEU A 87ARG A 228VAL A 195GLY A 196 | None | 0.82A | 2po5A-5ov6A:undetectable | 2po5A-5ov6A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5to3 | PROTHROMBIN,THROMBOMODULIN (Homo sapiens) |
PF00089(Trypsin)PF09064(Tme5_EGF_like) | 4 | MET B 118LEU B 96ARG B 35LEU B 42 | None | 1.02A | 2po5A-5to3B:undetectable | 2po5A-5to3B:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4v | RHOGTPASE-ACTIVATINGPROTEIN 5 (Homo sapiens) |
no annotation | 4 | LEU A 610LEU A 632VAL A 753GLY A 752 | None | 0.95A | 2po5A-5u4vA:3.4 | 2po5A-5u4vA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9l | PARALOG OFACCUMULATION ANDREPLICATION OFCHLOROPLASTS 6(PARC6) (Arabidopsisthaliana) |
no annotation | 4 | LEU A 708LEU A 721VAL A 643GLY A 644 | None | 0.68A | 2po5A-5u9lA:undetectable | 2po5A-5u9lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uti | QUEUINETRNA-RIBOSYLTRANSFERASE (Zymomonasmobilis) |
no annotation | 4 | ARG A 274LEU A 244VAL A 262GLY A 263 | None | 0.97A | 2po5A-5utiA:undetectable | 2po5A-5utiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve2 | ENOYL-COA HYDRATASE (Pseudoalteromonasatlantica) |
PF00378(ECH_1) | 4 | ARG A 161LEU A 163VAL A 148GLY A 149 | ARG A 161 ( 0.6A)LEU A 163 ( 0.5A)VAL A 148 ( 0.6A)GLY A 149 ( 0.0A) | 0.90A | 2po5A-5ve2A:undetectable | 2po5A-5ve2A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vu2 | E1 ENVELOPEGLYCOPROTEIN (Chikungunyavirus) |
no annotation | 4 | LEU M 38LEU M 33VAL M 163GLY M 164 | None | 0.90A | 2po5A-5vu2M:undetectable | 2po5A-5vu2M:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vxb | PROXP-ALA (Caulobactervibrioides) |
PF04073(tRNA_edit) | 4 | LEU A 152VAL A 95GLY A 94MET A 1 | None | 0.99A | 2po5A-5vxbA:undetectable | 2po5A-5vxbA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7y | LIPOCALIN-CAN F 6ALLERGEN (Canis lupus) |
no annotation | 4 | MET A 59LEU A 72LEU A 119GLY A 38 | MET A 59 ( 0.0A)LEU A 72 ( 0.6A)LEU A 119 ( 0.6A)GLY A 38 ( 0.0A) | 0.82A | 2po5A-5x7yA:undetectable | 2po5A-5x7yA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xii | PROLYL-TRNASYNTHETASE (PRORS) (Toxoplasmagondii) |
no annotation | 4 | LEU A 510PRO A 459VAL A 391GLY A 390 | None | 1.01A | 2po5A-5xiiA:3.6 | 2po5A-5xiiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxa | VARIABLE LYMPHOCYTERECEPTOR 2 (Petromyzonmarinus) |
no annotation | 4 | LEU C 109LEU C 102VAL C 92GLY C 91 | None | 1.00A | 2po5A-6bxaC:undetectable | 2po5A-6bxaC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cau | UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (Acinetobacterbaumannii) |
no annotation | 4 | LEU A 188ARG A 122GLY A 37MET A 35 | None | 0.78A | 2po5A-6cauA:undetectable | 2po5A-6cauA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6coy | CHLORIDE CHANNELPROTEIN 1 (Homo sapiens) |
no annotation | 4 | PRO A 420VAL A 229GLY A 230MET A 485 | NoneNone CL A1001 (-3.2A)None | 0.99A | 2po5A-6coyA:undetectable | 2po5A-6coyA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ct0 | DIHYDROLIPOYLLYSINE-RESIDUEACETYLTRANSFERASECOMPONENT OFPYRUVATEDEHYDROGENASECOMPLEX,MITOCHONDRIAL (Homo sapiens) |
no annotation | 4 | ARG 0 471LEU 0 468VAL 0 534GLY 0 533 | None | 0.95A | 2po5A-6ct00:undetectable | 2po5A-6ct00:undetectable |