SIMILAR PATTERNS OF AMINO ACIDS FOR 2PNC_A_CLUA808_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a2v | METHYLAMINE OXIDASE (Ogataea angusta) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 4 | TYR A 305ASP A 319TYR A 407HIS A 458 | TPQ A 405 ( 4.7A)TPQ A 405 ( 4.7A)None CU A 1 (-3.2A) | 0.40A | 2pncA-1a2vA:38.7 | 2pncA-1a2vA:24.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f1u | HOMOPROTOCATECHUATE2,3-DIOXYGENASE (Arthrobacterglobiformis) |
PF00903(Glyoxalase) | 4 | ALA A 253TYR A 269TYR A 257HIS A 248 | None | 1.29A | 2pncA-1f1uA:undetectable | 2pncA-1f1uA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iv8 | MALTOOLIGOSYLTREHALOSE SYNTHASE (Sulfolobusacidocaldarius) |
PF00128(Alpha-amylase)PF09196(DUF1953) | 4 | TYR A 274ASP A 228TYR A 50HIS A 442 | None | 1.34A | 2pncA-1iv8A:undetectable | 2pncA-1iv8A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0h | NEOPULLULANASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 4 | TYR A 377ASP A 328TYR A 207HIS A 423 | None | 1.45A | 2pncA-1j0hA:undetectable | 2pncA-1j0hA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcw | CERULOPLASMIN (Homo sapiens) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | ALA A 114TYR A 116ASP A 127HIS A 101 | NoneNoneNone CU A1052 (-3.2A) | 0.90A | 2pncA-1kcwA:undetectable | 2pncA-1kcwA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcw | CERULOPLASMIN (Homo sapiens) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | ALA A 114TYR A 116TYR A 107HIS A 101 | NoneNoneNone CU A1052 (-3.2A) | 1.37A | 2pncA-1kcwA:undetectable | 2pncA-1kcwA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nar | NARBONIN (Vicianarbonensis) |
PF00704(Glyco_hydro_18) | 4 | ALA A 165TYR A 174ASP A 128TYR A 8 | None | 1.27A | 2pncA-1narA:undetectable | 2pncA-1narA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1og6 | HYPOTHETICALOXIDOREDUCTASE YDHF (Escherichiacoli) |
PF00248(Aldo_ket_red) | 4 | ALA A 52TYR A 55MET A 207HIS A 128 | NoneNAP A1298 (-4.8A)NoneNAP A1298 (-4.6A) | 0.96A | 2pncA-1og6A:undetectable | 2pncA-1og6A:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1olp | ALPHA-TOXIN (Clostridiumsardiniense) |
PF00882(Zn_dep_PLPC)PF01477(PLAT) | 4 | ALA A 61TYR A 62ASP A 67TYR A 127 | None | 1.29A | 2pncA-1olpA:undetectable | 2pncA-1olpA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qaf | PROTEIN (COPPERAMINE OXIDASE) (Escherichiacoli) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3)PF07833(Cu_amine_oxidN1) | 4 | TYR A 369TYR A 381TYR A 468HIS A 526 | TPQ A 466 ( 4.4A)TPQ A 466 ( 4.1A)TPQ A 466 ( 3.8A) CU A 801 (-3.2A) | 0.57A | 2pncA-1qafA:37.6 | 2pncA-1qafA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sb3 | 4-HYDROXYBENZOYL-COAREDUCTASE ALPHASUBUNIT (Thaueraaromatica) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | ALA A 315TYR A 100ASP A 103HIS A 148 | None | 1.47A | 2pncA-1sb3A:undetectable | 2pncA-1sb3A:23.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u1h | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Arabidopsisthaliana) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | TYR A 94TYR A 65MET A 109TYR A 117 | None | 1.42A | 2pncA-1u1hA:undetectable | 2pncA-1u1hA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w7c | LYSYL OXIDASE (Komagataellapastoris) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF09248(DUF1965) | 6 | ALA A 382TYR A 384TYR A 396ASP A 398TYR A 480HIS A 530 | TPQ A 478 ( 4.6A)TPQ A 478 ( 4.7A)IMD A 821 (-3.5A)IMD A 821 (-2.6A)TPQ A 478 ( 3.9A) CU A 801 (-3.2A) | 0.52A | 2pncA-1w7cA:39.9 | 2pncA-1w7cA:28.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wom | SIGMA FACTOR SIGBREGULATION PROTEINRSBQ (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 4 | ALA A 222TYR A 125MET A 118HIS A 247 | NoneNoneNonePGO A 601 ( 4.7A) | 1.48A | 2pncA-1womA:undetectable | 2pncA-1womA:16.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xpg | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Thermotogamaritima) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | TYR A 90TYR A 64MET A 102TYR A 110 | None | 1.47A | 2pncA-1xpgA:undetectable | 2pncA-1xpgA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z1w | TRICORN PROTEASEINTERACTING FACTORF3 (Thermoplasmaacidophilum) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | ALA A 185TYR A 172MET A 95HIS A 220 | None | 1.18A | 2pncA-1z1wA:undetectable | 2pncA-1z1wA:21.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2c11 | MEMBRANE COPPERAMINE OXIDASE (Homo sapiens) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 6 | ALA A 370TYR A 372TYR A 384ASP A 386TYR A 473HIS A 522 | PAQ A 471 ( 3.2A)NonePAQ A 471 ( 3.6A)PAQ A 471 ( 2.6A)PAQ A 471 ( 4.5A) CU A1737 (-3.1A) | 0.32A | 2pncA-2c11A:55.2 | 2pncA-2c11A:81.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iw1 | LIPOPOLYSACCHARIDECORE BIOSYNTHESISPROTEIN RFAG (Escherichiacoli) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 4 | ALA A 125TYR A 121TYR A 103TYR A 155 | None | 1.07A | 2pncA-2iw1A:undetectable | 2pncA-2iw1A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k5d | UNCHARACTERIZEDPROTEIN SAG0934 (Streptococcusagalactiae) |
PF06125(DUF961) | 4 | ALA A 87TYR A 91TYR A 99ASP A 84 | None | 1.47A | 2pncA-2k5dA:undetectable | 2pncA-2k5dA:8.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pwh | SUCROSE ISOMERASE ([Pseudomonas]mesoacidophila) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 4 | ALA A 149TYR A 163TYR A 141MET A 219 | None | 1.32A | 2pncA-2pwhA:undetectable | 2pncA-2pwhA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyj | DNA POLYMERASE (Bacillus virusphi29) |
PF03175(DNA_pol_B_2) | 4 | ALA A 394TYR A 226TYR A 390MET A 258 | NoneNoneDGT A1588 (-4.4A)None | 1.47A | 2pncA-2pyjA:undetectable | 2pncA-2pyjA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q14 | PHOSPHOHYDROLASE (Bacteroidesthetaiotaomicron) |
PF01966(HD) | 4 | ALA A 51TYR A 48MET A 217HIS A 53 | None | 1.36A | 2pncA-2q14A:undetectable | 2pncA-2q14A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjp | CYTOCHROME B (Rhodobactersphaeroides) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 4 | ALA A 27TYR A 30ASP A 31HIS A 20 | None | 1.36A | 2pncA-2qjpA:undetectable | 2pncA-2qjpA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qr4 | PEPTIDASE M3B,OLIGOENDOPEPTIDASE F (Enterococcusfaecium) |
PF01432(Peptidase_M3)PF08439(Peptidase_M3_N) | 4 | ALA A 418MET A 568TYR A 555HIS A 398 | None | 1.37A | 2pncA-2qr4A:undetectable | 2pncA-2qr4A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpj | KELCH-LIKE PROTEIN12 (Homo sapiens) |
PF01344(Kelch_1) | 4 | TYR A 332TYR A 399ASP A 400HIS A 328 | None | 1.42A | 2pncA-2vpjA:undetectable | 2pncA-2vpjA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vuv | CODAKINE (Codakiaorbicularis) |
PF00059(Lectin_C) | 4 | ALA A 120TYR A 118ASP A 58HIS A 105 | NoneNoneGOL A 400 (-3.0A)None | 1.15A | 2pncA-2vuvA:undetectable | 2pncA-2vuvA:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vyc | BIODEGRADATIVEARGININEDECARBOXYLASE (Escherichiacoli) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | ALA A 354TYR A 353TYR A 360MET A 530 | None | 1.06A | 2pncA-2vycA:undetectable | 2pncA-2vycA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzs | PUTATIVEUNCHARACTERIZEDPROTEIN (Aquifexaeolicus) |
PF01867(Cas_Cas1) | 4 | ALA A 187TYR A 71TYR A 186HIS A 63 | None | 1.30A | 2pncA-2yzsA:undetectable | 2pncA-2yzsA:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z1k | (NEO)PULLULANASE (Thermusthermophilus) |
PF00128(Alpha-amylase) | 4 | TYR A 252ASP A 202TYR A 81HIS A 314 | NoneGLC A 603 (-2.6A)GLC A 603 ( 4.0A)GLC A 603 (-4.0A) | 1.41A | 2pncA-2z1kA:undetectable | 2pncA-2z1kA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z95 | GDP-D-MANNOSEDEHYDRATASE (Aquifexaeolicus) |
PF16363(GDP_Man_Dehyd) | 4 | ALA A 224TYR A 18TYR A 223MET A 330 | None | 1.37A | 2pncA-2z95A:undetectable | 2pncA-2z95A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3brz | TODX (Pseudomonasputida) |
PF03349(Toluene_X) | 4 | ALA A 279TYR A 239TYR A 303ASP A 306 | None | 1.23A | 2pncA-3brzA:undetectable | 2pncA-3brzA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebv | CHINITASE A (Streptomycescoelicolor) |
PF00704(Glyco_hydro_18) | 4 | ALA A 149TYR A 162ASP A 117TYR A 10 | None | 1.46A | 2pncA-3ebvA:undetectable | 2pncA-3ebvA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ga7 | ACETYL ESTERASE (Salmonellaenterica) |
PF07859(Abhydrolase_3) | 4 | ALA A 293TYR A 195MET A 301HIS A 296 | NoneSEP A 165 ( 4.6A)NoneNone | 1.39A | 2pncA-3ga7A:undetectable | 2pncA-3ga7A:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzy | BIPHENYL DIOXYGENASESUBUNIT ALPHA (Comamonastestosteroni) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | ALA A 274TYR A 193MET A 317HIS A 321 | None | 1.25A | 2pncA-3gzyA:undetectable | 2pncA-3gzyA:20.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3hig | AMILORIDE-SENSITIVEAMINE OXIDASE (Homo sapiens) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 6 | ALA A 357TYR A 359TYR A 371ASP A 373TYR A 463HIS A 512 | TPQ A 461 ( 4.9A)NoneBRN A 901 (-3.3A)BRN A 901 (-3.3A)TPQ A 461 ( 4.5A) CU A 801 (-3.2A) | 0.68A | 2pncA-3higA:46.1 | 2pncA-3higA:40.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hje | 704AA LONGHYPOTHETICALGLYCOSYLTRANSFERASE (Sulfurisphaeratokodaii) |
PF00128(Alpha-amylase)PF09196(DUF1953) | 4 | TYR A 269ASP A 222TYR A 48HIS A 440 | NoneGOL A 802 (-2.8A)GOL A 802 ( 4.3A)None | 1.41A | 2pncA-3hjeA:undetectable | 2pncA-3hjeA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ip3 | OXIDOREDUCTASE,PUTATIVE (Thermotogamaritima) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | TYR A 15ASP A 246TYR A 158HIS A 183 | None | 1.37A | 2pncA-3ip3A:undetectable | 2pncA-3ip3A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq4 | CUBILIN (Homo sapiens) |
PF00431(CUB) | 4 | ALA B1031TYR B1032ASP B 988HIS B 954 | NoneNone CA B2014 (-3.2A)None | 1.46A | 2pncA-3kq4B:undetectable | 2pncA-3kq4B:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l0s | ADENYLATE KINASE (Desulfovibriogigas) |
PF00406(ADK) | 4 | ALA A 188TYR A 202TYR A 189TYR A 177 | None | 1.18A | 2pncA-3l0sA:undetectable | 2pncA-3l0sA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3loy | COPPER AMINE OXIDASE (Ogataea angusta) |
PF01179(Cu_amine_oxid) | 4 | TYR A 288ASP A 302TYR A 388HIS A 438 | TPQ A 386 ( 4.3A)TPQ A 386 ( 4.9A)TPQ A 386 ( 4.1A) CU A 635 (-3.2A) | 0.67A | 2pncA-3loyA:35.9 | 2pncA-3loyA:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mvj | CAMP-DEPENDENTPROTEIN KINASECATALYTIC SUBUNITALPHA (Homo sapiens) |
PF00069(Pkinase) | 4 | ALA A 233TYR A 235TYR A 229HIS A 260 | None | 1.32A | 2pncA-3mvjA:undetectable | 2pncA-3mvjA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ops | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Paenibacillussp. Y412MC10) |
PF13378(MR_MLE_C) | 4 | ALA A 30ASP A 338TYR A 313HIS A 39 | NoneNoneTAR A 504 (-4.5A)TAR A 504 ( 4.6A) | 1.31A | 2pncA-3opsA:undetectable | 2pncA-3opsA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ops | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Paenibacillussp. Y412MC10) |
PF13378(MR_MLE_C) | 4 | ALA A 321TYR A 317TYR A 350HIS A 324 | None | 1.23A | 2pncA-3opsA:undetectable | 2pncA-3opsA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE BETA-SUBUNIT (Komagataellapastoris) |
PF00365(PFK) | 4 | TYR B 752TYR B 711ASP B 509TYR B 480 | None | 1.46A | 2pncA-3opyB:undetectable | 2pncA-3opyB:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pgb | PUTATIVEUNCHARACTERIZEDPROTEIN (Aspergillusnidulans) |
PF01179(Cu_amine_oxid)PF09248(DUF1965) | 6 | ALA A 407TYR A 409TYR A 421ASP A 423TYR A 506HIS A 554 | TPQ A 504 ( 3.9A)TPQ A 504 ( 4.7A)TPQ A 504 ( 3.8A)TPQ A 504 ( 4.3A)TPQ A 504 ( 4.2A) CU A 901 (-3.2A) | 0.52A | 2pncA-3pgbA:38.2 | 2pncA-3pgbA:29.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjz | N-TYPE ATPPYROPHOSPHATASESUPERFAMILY (Pyrococcusfuriosus) |
PF01902(Diphthami_syn_2) | 4 | ALA A 181TYR A 131ASP A 16HIS A 179 | None | 1.44A | 2pncA-3rjzA:undetectable | 2pncA-3rjzA:14.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rm5 | HYDROXYMETHYLPYRIMIDINE/PHOSPHOMETHYLPYRIMIDINE KINASE THI20 (Saccharomycescerevisiae) |
PF03070(TENA_THI-4)PF08543(Phos_pyr_kin) | 4 | ALA A 273TYR A 269TYR A 295HIS A 293 | None | 1.44A | 2pncA-3rm5A:undetectable | 2pncA-3rm5A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wcz | ALDO-KETO REDUCTASE2E (Bombyx mori) |
PF00248(Aldo_ket_red) | 4 | ALA A 55TYR A 58MET A 204HIS A 120 | NoneCIT A 406 ( 3.2A)NoneNAP A 401 (-4.0A) | 1.06A | 2pncA-3wczA:undetectable | 2pncA-3wczA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x3y | PHENYLETHYLAMINEOXIDASE (Arthrobacterglobiformis) |
PF01179(Cu_amine_oxid)PF02728(Cu_amine_oxidN3) | 5 | TYR A 284TYR A 296ASP A 298TYR A 384HIS A 433 | NoneTYQ A 382 ( 4.8A)NoneTYQ A 382 ( 4.2A) CU A 701 (-3.2A) | 0.87A | 2pncA-3x3yA:35.9 | 2pncA-3x3yA:24.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bjm | AVRM (Melampsora lini) |
no annotation | 4 | ALA A 223TYR A 219TYR A 180TYR A 243 | None | 1.29A | 2pncA-4bjmA:undetectable | 2pncA-4bjmA:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bug | ANCILLARY PROTEIN 1 (Streptococcuspyogenes) |
PF08341(TED) | 4 | ALA A 553TYR A 552ASP A 555HIS A 481 | None | 1.45A | 2pncA-4bugA:undetectable | 2pncA-4bugA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cak | INTEGRIN ALPHA-IIBINTEGRIN BETA-3 (Homo sapiens) |
PF00362(Integrin_beta)PF01839(FG-GAP)PF07965(Integrin_B_tail)PF07974(EGF_2)PF08441(Integrin_alpha2)PF17205(PSI_integrin) | 4 | ALA B 172TYR B 178ASP A 232TYR A 234 | None | 1.20A | 2pncA-4cakB:undetectable | 2pncA-4cakB:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dhi | UBIQUITINTHIOESTERASEOTUBAIN-LIKE (Caenorhabditiselegans) |
PF10275(Peptidase_C65) | 4 | ALA B 217TYR B 90ASP B 214TYR B 201 | None | 1.14A | 2pncA-4dhiB:undetectable | 2pncA-4dhiB:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eis | POLYSACCHARIDEMONOOXYGENASE-3 (Neurosporacrassa) |
PF03443(Glyco_hydro_61) | 4 | ALA B 158TYR B 171MET B 131HIS B 160 | NoneHIC B 1 (-3.5A)NoneNone | 1.31A | 2pncA-4eisB:undetectable | 2pncA-4eisB:14.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4epa | PESTICIN RECEPTOR (Yersinia pestis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | ALA A 359TYR A 327ASP A 383TYR A 433 | None | 1.29A | 2pncA-4epaA:undetectable | 2pncA-4epaA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0j | PROBABLE HYDROLYTICENZYME (Pseudomonasaeruginosa) |
PF00561(Abhydrolase_1) | 4 | ALA A 79TYR A 36MET A 221HIS A 73 | None | 1.48A | 2pncA-4f0jA:undetectable | 2pncA-4f0jA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4foz | PORIN D (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | ALA A 264TYR A 327TYR A 320HIS A 265 | None | 1.27A | 2pncA-4fozA:undetectable | 2pncA-4fozA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gm6 | PFKB FAMILYCARBOHYDRATE KINASE (Listeria grayi) |
PF00294(PfkB) | 4 | ALA A 228TYR A 272TYR A 227TYR A 213 | None | 1.35A | 2pncA-4gm6A:undetectable | 2pncA-4gm6A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ivi | CARBOXYLESTERASE (unculturedbacterium) |
PF00144(Beta-lactamase) | 4 | ALA A 347TYR A 348ASP A 217TYR A 210 | None | 1.28A | 2pncA-4iviA:undetectable | 2pncA-4iviA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcm | CYCLODEXTRINGLUCANOTRANSFERASE ([Bacillus]clarkii) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | ASP A 272MET A 296TYR A 304HIS A 260 | None | 1.40A | 2pncA-4jcmA:undetectable | 2pncA-4jcmA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jqs | HYPOTHETICAL PROTEIN (Bacteroidesuniformis) |
PF06283(ThuA) | 4 | ALA A 121TYR A 180TYR A 124HIS A 48 | None | 1.07A | 2pncA-4jqsA:undetectable | 2pncA-4jqsA:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kry | ACETYL ESTERASE (Escherichiacoli) |
PF07859(Abhydrolase_3) | 4 | ALA A 293TYR A 195MET A 301HIS A 296 | NoneSEB A 165 ( 4.8A)NoneNone | 1.37A | 2pncA-4kryA:undetectable | 2pncA-4kryA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mve | UNCHARACTERIZEDPROTEIN (Thermomonosporacurvata) |
PF14231(GXWXG)PF14232(DUF4334) | 4 | ALA A 130TYR A 26TYR A 141HIS A 118 | None | 1.47A | 2pncA-4mveA:undetectable | 2pncA-4mveA:12.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmj | PUTATIVEOXIDOREDUCTASE (Sinorhizobiummeliloti) |
PF00248(Aldo_ket_red) | 4 | ALA A 54TYR A 57MET A 193HIS A 115 | NoneNoneNoneNAP A 301 (-4.4A) | 1.08A | 2pncA-4pmjA:undetectable | 2pncA-4pmjA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qsg | GAS VESICLE PROTEIN (Microcystisaeruginosa) |
PF06386(GvpL_GvpF) | 4 | ALA A 44TYR A 49TYR A 6HIS A 45 | None | 1.33A | 2pncA-4qsgA:undetectable | 2pncA-4qsgA:16.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9o | PUTATIVE ALDO/KETOREDUCTASE (Salmonellaenterica) |
PF00248(Aldo_ket_red) | 4 | ALA A 52TYR A 55MET A 207HIS A 128 | None | 1.04A | 2pncA-4r9oA:undetectable | 2pncA-4r9oA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rl3 | CHITINASE A (Pterisryukyuensis) |
PF00704(Glyco_hydro_18) | 4 | ALA A 280TYR A 289ASP A 243TYR A 130 | ACT A 403 ( 4.1A)NoneNoneACT A 403 (-3.9A) | 1.48A | 2pncA-4rl3A:undetectable | 2pncA-4rl3A:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ru0 | PUTATIVEBRANCHED-CHAIN AMINOACID ABCTRANSPORTER,PERIPLASMICBRANCHED-CHAIN AMINOACID-BINDING PROTEIN (Pseudomonasprotegens) |
PF13458(Peripla_BP_6) | 4 | TYR A 374TYR A 57TYR A 324HIS A 298 | None | 1.41A | 2pncA-4ru0A:undetectable | 2pncA-4ru0A:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4thi | PROTEIN (THIAMINASEI) (Bacillussubtilis) |
PF01547(SBP_bac_1) | 4 | TYR A 239TYR A 270ASP A 64TYR A 16 | PYD A 371 (-4.2A)PYD A 371 ( 3.7A)NoneNone | 1.42A | 2pncA-4thiA:undetectable | 2pncA-4thiA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u7t | DNA(CYTOSINE-5)-METHYLTRANSFERASE 3A (Homo sapiens) |
PF00145(DNA_methylase) | 4 | ALA A 644TYR A 660TYR A 874HIS A 677 | None | 1.45A | 2pncA-4u7tA:undetectable | 2pncA-4u7tA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wb7 | DNAJ HOMOLOGSUBFAMILY B MEMBER1,CAMP-DEPENDENTPROTEIN KINASECATALYTIC SUBUNITALPHA (Homo sapiens) |
PF00069(Pkinase)PF00226(DnaJ) | 4 | ALA A 288TYR A 290TYR A 284HIS A 315 | None | 1.29A | 2pncA-4wb7A:undetectable | 2pncA-4wb7A:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xpx | BACTERIOHEMERYTHRIN (Methylococcuscapsulatus) |
PF01814(Hemerythrin) | 4 | ALA A 18TYR A 125MET A 57HIS A 22 | NoneNoneNoneFE2 A 202 (-3.3A) | 1.11A | 2pncA-4xpxA:undetectable | 2pncA-4xpxA:11.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y9s | EPOXIDE HYDROLASE (Solanumtuberosum) |
PF00561(Abhydrolase_1) | 4 | TYR A 46TYR A 315ASP A 316HIS A 308 | None | 1.24A | 2pncA-4y9sA:undetectable | 2pncA-4y9sA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yt9 | PEPTIDYLARGININEDEIMINASE (Porphyromonasgingivalis) |
PF04371(PAD_porph) | 4 | ALA A 277TYR A 367TYR A 189ASP A 187 | None | 1.19A | 2pncA-4yt9A:undetectable | 2pncA-4yt9A:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z61 | PHYTOSULFOKINERECEPTOR 1 (Daucus carota) |
PF00560(LRR_1)PF13855(LRR_8) | 4 | ALA A 190TYR A 165ASP A 188TYR A 210 | None | 1.27A | 2pncA-4z61A:undetectable | 2pncA-4z61A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo6 | LIN1840 PROTEIN (Listeriainnocua) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | ALA A 237TYR A 196ASP A 140TYR A 223 | None | 1.48A | 2pncA-4zo6A:undetectable | 2pncA-4zo6A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo6 | LIN1840 PROTEIN (Listeriainnocua) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | ALA A 237TYR A 196MET A 138TYR A 223 | None | 1.39A | 2pncA-4zo6A:undetectable | 2pncA-4zo6A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c8c | VP0VP1 (Enterovirus A) |
PF00073(Rhv)PF02226(Pico_P1A) | 4 | TYR B 148TYR B 199ASP A 206TYR A 222 | None | 1.45A | 2pncA-5c8cB:undetectable | 2pncA-5c8cB:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dmy | BETA-GALACTOSIDASE (Bifidobacteriumbifidum) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 4 | TYR A 167MET A 116TYR A 134HIS A 328 | None | 1.11A | 2pncA-5dmyA:undetectable | 2pncA-5dmyA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5et1 | ESPINMYOSIN-IIIB (Mus musculus) |
PF12796(Ank_2)PF13637(Ank_4)PF13857(Ank_5)no annotation | 4 | ALA A 105ASP C1264TYR C1268HIS A 75 | None | 1.38A | 2pncA-5et1A:undetectable | 2pncA-5et1A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffj | ENDONUCLEASE ANDMETHYLASE LLAGI (Lactococcuslactis) |
PF00271(Helicase_C)PF02384(N6_Mtase)PF04851(ResIII) | 4 | ALA A 340TYR A 404TYR A 372TYR A 315 | None | 1.22A | 2pncA-5ffjA:undetectable | 2pncA-5ffjA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gam | PRE-MRNA-SPLICINGFACTOR 8 (Saccharomycescerevisiae) |
PF08082(PRO8NT)PF08083(PROCN) | 4 | ALA A 164TYR A 167TYR A 556HIS A 194 | None | 1.34A | 2pncA-5gamA:undetectable | 2pncA-5gamA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gs2 | ANTI-MBPANTI-REPEBODY (Homo sapiens;Mus musculus) |
PF07686(V-set) | 4 | ALA D 107TYR D 105TYR H 181TYR H 168 | None | 1.19A | 2pncA-5gs2D:undetectable | 2pncA-5gs2D:15.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k0y | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT GEUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT I (Homo sapiens;Oryctolaguscuniculus) |
PF00400(WD40)PF12353(eIF3g) | 4 | ALA T 267TYR T 300MET M 128HIS T 284 | None | 1.39A | 2pncA-5k0yT:undetectable | 2pncA-5k0yT:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k59 | UNCHARACTERIZEDLEUKOCIDIN-LIKEPROTEIN 1 (Staphylococcusaureus) |
no annotation | 4 | ALA B 103TYR B 115TYR B 117ASP B 101 | None | 1.40A | 2pncA-5k59B:undetectable | 2pncA-5k59B:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpd | 26S PROTEASOMEREGULATORY SUBUNITRPN6 (Saccharomycescerevisiae) |
PF01399(PCI) | 4 | ALA Q 258TYR Q 291TYR Q 255HIS Q 247 | None | 1.46A | 2pncA-5mpdQ:undetectable | 2pncA-5mpdQ:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n4l | CERULOPLASMIN (Rattusnorvegicus) |
no annotation | 4 | ALA A 114TYR A 116ASP A 127HIS A 101 | NoneNone CA A1106 (-2.6A) CU A1105 (-3.1A) | 0.91A | 2pncA-5n4lA:undetectable | 2pncA-5n4lA:6.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ogs | WD REPEAT ANDHMG-BOX DNA-BINDINGPROTEIN 1 (Homo sapiens) |
no annotation | 4 | ALA A 465TYR A 458ASP A 463HIS A 480 | None | 1.32A | 2pncA-5ogsA:undetectable | 2pncA-5ogsA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ot1 | PULLULANASE TYPE II,GH13 FAMILY (Thermococcuskodakarensis) |
no annotation | 4 | TYR A 346ASP A 384TYR A 386HIS A 315 | None | 1.39A | 2pncA-5ot1A:undetectable | 2pncA-5ot1A:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xau | LAMININ SUBUNITALPHA-5 (Homo sapiens) |
PF02210(Laminin_G_2)PF06009(Laminin_II) | 4 | ALA A3205TYR A3207TYR A3216ASP A3219 | NoneNoneNone CA A3401 (-3.9A) | 1.19A | 2pncA-5xauA:undetectable | 2pncA-5xauA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y70 | KINETOPLASTIDMEMBRANE PROTEIN 11 (Trypanosomabrucei) |
no annotation | 4 | ALA A 9ASP A 13MET A 54HIS A 47 | None | 1.43A | 2pncA-5y70A:undetectable | 2pncA-5y70A:8.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b6l | GLYCOSYL HYDROLASEFAMILY 2, SUGARBINDING DOMAINPROTEIN (Bacteroidescellulosilyticus) |
no annotation | 4 | TYR A 171MET A 120TYR A 138HIS A 325 | None | 1.19A | 2pncA-6b6lA:undetectable | 2pncA-6b6lA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bc5 | AAC 3-VI PROTEIN (Enterobactercloacae) |
no annotation | 4 | ALA A 158ASP A 136MET A 207TYR A 205 | None | 1.38A | 2pncA-6bc5A:undetectable | 2pncA-6bc5A:7.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bc5 | AAC 3-VI PROTEIN (Enterobactercloacae) |
no annotation | 4 | ALA A 158TYR A 159TYR A 205HIS A 134 | None | 1.35A | 2pncA-6bc5A:undetectable | 2pncA-6bc5A:7.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byi | BETA-MANNOSIDASE (Xanthomonascitri) |
no annotation | 4 | ALA A 694TYR A 666TYR A 698HIS A 691 | None | 1.02A | 2pncA-6byiA:undetectable | 2pncA-6byiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ch0 | - (-) |
no annotation | 4 | ALA C 199TYR C 239TYR C 158HIS C 120 | NoneNoneNone CO C 302 ( 3.1A) | 1.45A | 2pncA-6ch0C:undetectable | 2pncA-6ch0C:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cia | ALDO/KETO REDUCTASE (Klebsiellapneumoniae) |
no annotation | 4 | ALA A 52TYR A 55MET A 191HIS A 113 | NoneNDP A 301 (-4.6A)NoneNDP A 301 (-4.3A) | 1.03A | 2pncA-6ciaA:undetectable | 2pncA-6ciaA:7.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dk2 | - (-) |
no annotation | 4 | ALA A 492TYR A 139TYR A 50HIS A 59 | None | 0.99A | 2pncA-6dk2A:undetectable | 2pncA-6dk2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f8z | ALPHA-1,2-MANNOSIDASE, PUTATIVE (Bacteroidesthetaiotaomicron) |
no annotation | 4 | ALA A 331TYR A 329TYR A 383ASP A 333 | None | 1.36A | 2pncA-6f8zA:undetectable | 2pncA-6f8zA:7.93 |