SIMILAR PATTERNS OF AMINO ACIDS FOR 2P2F_A_ACTA653_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bfo | CAMPATH-1G ANTIBODY (Rattus rattus) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL A 132VAL A 158GLY A 157TRP A 148 | None | 1.14A | 2p2fA-1bfoA:undetectable | 2p2fA-1bfoA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1egz | ENDOGLUCANASE Z (Dickeyachrysanthemi) |
PF00150(Cellulase) | 4 | VAL A 224THR A 223VAL A 280GLY A 277 | None | 1.01A | 2p2fA-1egzA:undetectable | 2p2fA-1egzA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1epx | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE (Leishmaniamexicana) |
PF00274(Glycolytic) | 4 | VAL A 223VAL A 231GLY A 230TRP A 233 | None | 0.91A | 2p2fA-1epxA:2.3 | 2p2fA-1epxA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f2j | FRUCTOSE-BISPHOSPHATE ALDOLASE,GLYCOSOMAL (Trypanosomabrucei) |
PF00274(Glycolytic) | 4 | VAL A 223VAL A 231GLY A 230TRP A 233 | None | 0.96A | 2p2fA-1f2jA:2.2 | 2p2fA-1f2jA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h5q | NADP-DEPENDENTMANNITOLDEHYDROGENASE (Agaricusbisporus) |
PF13561(adh_short_C2) | 4 | VAL A 55THR A 52VAL A 40GLY A 19 | None | 1.14A | 2p2fA-1h5qA:2.6 | 2p2fA-1h5qA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hbz | CATALASE (Micrococcusluteus) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | VAL A 181THR A 182VAL A 472TRP A 469 | None | 1.06A | 2p2fA-1hbzA:undetectable | 2p2fA-1hbzA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hl2 | N-ACETYLNEURAMINATELYASE SUBUNIT (Escherichiacoli) |
PF00701(DHDPS) | 4 | VAL A 106THR A 107VAL A 145GLY A 144 | None | 1.15A | 2p2fA-1hl2A:undetectable | 2p2fA-1hl2A:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oxj | RNA-BINDING PROTEINSMAUG (Drosophilamelanogaster) |
PF00536(SAM_1)PF09246(PHAT) | 4 | VAL A 685THR A 682VAL A 732TRP A 735 | None | 1.15A | 2p2fA-1oxjA:undetectable | 2p2fA-1oxjA:13.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p3y | MRSD PROTEIN (Bacillus sp.HIL-Y85/54728) |
PF02441(Flavoprotein) | 4 | VAL 1 111THR 1 110VAL 1 41GLY 1 14 | None | 0.89A | 2p2fA-1p3y1:3.6 | 2p2fA-1p3y1:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qpo | QUINOLINATE ACIDPHOSPHORIBOSYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 4 | VAL A 226THR A 229VAL A 264GLY A 263 | None | 1.05A | 2p2fA-1qpoA:2.0 | 2p2fA-1qpoA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rcq | CATABOLIC ALANINERACEMASE DADX (Pseudomonasaeruginosa) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | VAL A 267THR A 305VAL A 251GLY A 252 | None | 1.04A | 2p2fA-1rcqA:undetectable | 2p2fA-1rcqA:21.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ry2 | ACETYL-COENZYME ASYNTHETASE 1 (Saccharomycescerevisiae) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 4 | THR A 367VAL A 442GLY A 443TRP A 470 | NoneAMP A 720 ( 4.7A)AMP A 720 (-3.9A)None | 0.38A | 2p2fA-1ry2A:55.0 | 2p2fA-1ry2A:45.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tvp | CELLULASE (Pseudoalteromonashaloplanktis) |
PF00150(Cellulase) | 4 | VAL A 226THR A 225VAL A 284GLY A 281 | None | 1.02A | 2p2fA-1tvpA:2.1 | 2p2fA-1tvpA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5v | CITE (Mycobacteriumtuberculosis) |
PF03328(HpcH_HpaI) | 4 | VAL A 62THR A 87VAL A 130GLY A 131 | None | 0.99A | 2p2fA-1u5vA:undetectable | 2p2fA-1u5vA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uar | RHODANESE (Thermusthermophilus) |
PF00581(Rhodanese) | 4 | VAL A 15THR A 12GLY A 114TRP A 118 | None | 1.03A | 2p2fA-1uarA:undetectable | 2p2fA-1uarA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uax | RIBONUCLEASE HII (Pyrococcushorikoshii) |
PF01351(RNase_HII) | 4 | VAL A 150THR A 151VAL A 65GLY A 21 | None | 0.74A | 2p2fA-1uaxA:undetectable | 2p2fA-1uaxA:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ufl | NITROGEN REGULATORYPROTEIN P-II (Thermusthermophilus) |
PF00543(P-II) | 4 | VAL A 74THR A 73VAL A 65GLY A 64 | None | 1.15A | 2p2fA-1uflA:2.5 | 2p2fA-1uflA:10.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc3 | PUTATIVEFRUCTOKINASE (Bacillussubtilis) |
PF00480(ROK) | 4 | VAL A 104THR A 102VAL A 61GLY A 59 | GOL A 305 ( 4.6A)GOL A 305 ( 4.1A)NoneGOL A 305 (-3.2A) | 1.14A | 2p2fA-1xc3A:2.4 | 2p2fA-1xc3A:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zan | FAB AD11 LIGHT CHAIN (Rattusnorvegicus) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL L 133VAL L 160GLY L 159TRP L 149 | None | 1.13A | 2p2fA-1zanL:undetectable | 2p2fA-1zanL:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b2x | ANTIBODY AQC2 FAB (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL L 136VAL L 163GLY L 162TRP L 152 | None | 1.15A | 2p2fA-2b2xL:undetectable | 2p2fA-2b2xL:14.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3x | IRON-RESPONSIVEELEMENT BINDINGPROTEIN 1 (Homo sapiens) |
PF00330(Aconitase)PF00694(Aconitase_C) | 4 | VAL A 478THR A 479VAL A 498GLY A 500 | None | 1.14A | 2p2fA-2b3xA:2.6 | 2p2fA-2b3xA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3t | FATTY OXIDATIONCOMPLEX ALPHASUBUNIT (Pseudomonasfragi) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 4 | VAL A 479THR A 478VAL A 448GLY A 449 | None | 0.96A | 2p2fA-2d3tA:undetectable | 2p2fA-2d3tA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dt8 | DEGV FAMILY PROTEIN (Thermusthermophilus) |
PF02645(DegV) | 4 | VAL A 25THR A 7VAL A 126GLY A 123 | None | 1.13A | 2p2fA-2dt8A:2.8 | 2p2fA-2dt8A:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f86 | HYPOTHETICAL PROTEINK11E8.1D (Caenorhabditiselegans) |
PF08332(CaMKII_AD) | 4 | VAL B 356THR B 357VAL B 429TRP B 455 | None | 0.62A | 2p2fA-2f86B:undetectable | 2p2fA-2f86B:11.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l04 | MAJOR TAIL PROTEIN V (Escherichiavirus Lambda) |
PF02368(Big_2) | 4 | VAL A 207THR A 206VAL A 219GLY A 218 | None | 1.04A | 2p2fA-2l04A:undetectable | 2p2fA-2l04A:8.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nym | SERINE/THREONINE-PROTEIN PHOSPHATASE 2ACATALYTIC SUBUNITALPHA ISOFORM (Homo sapiens) |
PF00149(Metallophos) | 4 | VAL C 257THR C 258VAL C 244GLY C 247 | None | 1.15A | 2p2fA-2nymC:undetectable | 2p2fA-2nymC:20.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2p2m | ACETYL-COENZYME ASYNTHETASE (Salmonellaenterica) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 5 | VAL A 310THR A 311VAL A 386GLY A 387TRP A 414 | NonePRX A 998 (-4.3A)NonePRX A 998 (-3.4A)PRX A 998 (-3.4A) | 0.17A | 2p2fA-2p2mA:66.8 | 2p2fA-2p2mA:99.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q8n | GLUCOSE-6-PHOSPHATEISOMERASE (Thermotogamaritima) |
PF00342(PGI) | 4 | VAL A 201THR A 203VAL A 195GLY A 196 | None | 1.10A | 2p2fA-2q8nA:3.7 | 2p2fA-2q8nA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4k | DEATH-ASSOCIATEDPROTEIN KINASE 1 (Homo sapiens) |
PF00069(Pkinase) | 4 | VAL A 232VAL A 205GLY A 204TRP A 201 | None | 1.11A | 2p2fA-2w4kA:undetectable | 2p2fA-2w4kA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9s | D-ARABINOSEISOMERASE (Aeribacilluspallidus) |
PF02952(Fucose_iso_C)PF07881(Fucose_iso_N1)PF07882(Fucose_iso_N2) | 4 | VAL A 485THR A 484VAL A 462GLY A 482 | None | 1.15A | 2p2fA-3a9sA:3.4 | 2p2fA-3a9sA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqu | AT4G19810 (Arabidopsisthaliana) |
PF00704(Glyco_hydro_18) | 4 | VAL A 307THR A 308VAL A 287GLY A 288 | None | 1.09A | 2p2fA-3aquA:undetectable | 2p2fA-3aquA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b46 | AMINOTRANSFERASEBNA3 (Saccharomycescerevisiae) |
PF00155(Aminotran_1_2) | 4 | VAL A 34THR A 38VAL A 399GLY A 60 | None | 1.10A | 2p2fA-3b46A:undetectable | 2p2fA-3b46A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqr | DEATH-ASSOCIATEDPROTEIN KINASE 3 (Homo sapiens) |
PF00069(Pkinase) | 4 | VAL A 232VAL A 205GLY A 204TRP A 201 | None | 1.07A | 2p2fA-3bqrA:undetectable | 2p2fA-3bqrA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c28 | RECOMBINASE CRE (Escherichiavirus P1) |
PF00589(Phage_integrase) | 4 | VAL A 242VAL A 230GLY A 229TRP A 224 | None | 1.15A | 2p2fA-3c28A:undetectable | 2p2fA-3c28A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvh | 25-D1.16 LIGHT CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL L 131VAL L 158GLY L 157TRP L 147 | None | 1.14A | 2p2fA-3cvhL:undetectable | 2p2fA-3cvhL:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3czp | PUTATIVEPOLYPHOSPHATE KINASE2 (Pseudomonasaeruginosa) |
PF03976(PPK2) | 4 | VAL A 58THR A 57VAL A 223GLY A 224 | None | 1.13A | 2p2fA-3czpA:undetectable | 2p2fA-3czpA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8v | FLAGELLIN HOMOLOG (Sphingomonassp. A1) |
PF00669(Flagellin_N)PF00700(Flagellin_C)PF07196(Flagellin_IN) | 4 | VAL A 234THR A 232VAL A 203GLY A 202 | None | 1.10A | 2p2fA-3k8vA:undetectable | 2p2fA-3k8vA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ktd | PREPHENATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF02153(PDH) | 4 | VAL A 171VAL A 120GLY A 121TRP A 167 | None | 1.15A | 2p2fA-3ktdA:4.4 | 2p2fA-3ktdA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxw | SAFRAMYCIN MX1SYNTHETASE B (Legionellapneumophila) |
PF00501(AMP-binding) | 4 | VAL A 451THR A 452VAL A 397GLY A 398 | 1ZZ A 589 (-4.4A)NoneNoneNone | 1.06A | 2p2fA-3kxwA:32.6 | 2p2fA-3kxwA:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ndo | DEOXYRIBOSE-PHOSPHATE ALDOLASE (Mycolicibacteriumsmegmatis) |
PF01791(DeoC) | 4 | VAL A 27THR A 28VAL A 55GLY A 54 | None | 1.14A | 2p2fA-3ndoA:2.3 | 2p2fA-3ndoA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0r | ANTIBODY FABFRAGMENT LIGHT CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL L 132VAL L 159GLY L 158TRP L 148 | None | 1.15A | 2p2fA-3o0rL:undetectable | 2p2fA-3o0rL:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pbk | FATTY ACYL-ADENYLATELIGASE (Escherichiacoli) |
PF00501(AMP-binding) | 4 | VAL A 456THR A 457VAL A 411GLY A 412 | 1ZZ A 1 (-4.1A)NoneNoneNone | 1.07A | 2p2fA-3pbkA:31.3 | 2p2fA-3pbkA:25.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3v | PHOSPHOGLYCERATEKINASE (Campylobacterjejuni) |
PF00162(PGK) | 4 | VAL A 359THR A 356GLY A 198TRP A 319 | None | 0.98A | 2p2fA-3q3vA:2.9 | 2p2fA-3q3vA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3v | PHOSPHOGLYCERATEKINASE (Campylobacterjejuni) |
PF00162(PGK) | 4 | VAL A 359THR A 356GLY A 199TRP A 319 | None | 1.15A | 2p2fA-3q3vA:2.9 | 2p2fA-3q3vA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3v | PHOSPHOGLYCERATEKINASE (Campylobacterjejuni) |
PF00162(PGK) | 4 | VAL A 359VAL A 351GLY A 352TRP A 319 | None | 0.82A | 2p2fA-3q3vA:2.9 | 2p2fA-3q3vA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qnq | PTS SYSTEM,CELLOBIOSE-SPECIFICIIC COMPONENT (Bacillus cereus) |
PF02378(PTS_EIIC) | 4 | VAL A 109THR A 110VAL A 193GLY A 190 | None | 1.09A | 2p2fA-3qnqA:undetectable | 2p2fA-3qnqA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s99 | BASIC MEMBRANELIPOPROTEIN (Brucellaabortus) |
PF02608(Bmp) | 4 | VAL A 23THR A 57VAL A 48GLY A 52 | NoneNoneIOD A 367 ( 4.8A)None | 1.07A | 2p2fA-3s99A:6.2 | 2p2fA-3s99A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdf | DIHYDRODIPICOLINATESYNTHASE (Acinetobacterbaumannii) |
PF00701(DHDPS) | 4 | VAL A 103THR A 104VAL A 141GLY A 140 | None | 1.08A | 2p2fA-3tdfA:undetectable | 2p2fA-3tdfA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujg | SERINE/THREONINE-PROTEIN KINASE SRK2E (Arabidopsisthaliana) |
PF00069(Pkinase) | 4 | VAL A 236VAL A 205GLY A 204TRP A 201 | None | 1.08A | 2p2fA-3ujgA:undetectable | 2p2fA-3ujgA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4y | SERINE/THREONINE-PROTEIN PHOSPHATASEPP1-ALPHA CATALYTICSUBUNIT (Homo sapiens) |
PF00149(Metallophos)PF16891(STPPase_N) | 4 | VAL A 264THR A 265VAL A 251GLY A 254 | None | 1.12A | 2p2fA-3v4yA:undetectable | 2p2fA-3v4yA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vf1 | 11R-LIPOXYGENASE (Gersemiafruticosa) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | VAL A 604THR A 605VAL A 187GLY A 188 | None | 1.10A | 2p2fA-3vf1A:undetectable | 2p2fA-3vf1A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w5f | BETA-GALACTOSIDASE (Solanumlycopersicum) |
PF01301(Glyco_hydro_35) | 4 | VAL A 157VAL A 211GLY A 210TRP A 213 | NoneNone CL A 808 (-3.3A)None | 0.97A | 2p2fA-3w5fA:1.2 | 2p2fA-3w5fA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zid | TUBULIN/FTSZ, GTPASE (Methanothrixthermoacetophila) |
PF00091(Tubulin) | 4 | VAL A 69THR A 50VAL A 75GLY A 82 | None | 1.10A | 2p2fA-3zidA:2.8 | 2p2fA-3zidA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4af3 | AURORA KINASE B (Homo sapiens) |
PF00069(Pkinase) | 4 | VAL A 288VAL A 261GLY A 260TRP A 257 | None | 1.02A | 2p2fA-4af3A:undetectable | 2p2fA-4af3A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4amf | PHOX (Pseudomonasfluorescens) |
PF05787(DUF839) | 4 | VAL A 250THR A 191VAL A 119GLY A 118 | None | 1.10A | 2p2fA-4amfA:undetectable | 2p2fA-4amfA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b7g | CATALASE (Corynebacteriumglutamicum) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | VAL A 191THR A 192VAL A 499TRP A 496 | None | 1.03A | 2p2fA-4b7gA:undetectable | 2p2fA-4b7gA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4crn | ERF3 IN RIBOSOMEBOUNDERF1-ERF3-GDPNPCOMPLEXERF1 INRIBOSOME-BOUNDERF1-ERF3-GDPNPCOMPLEX (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2)PF03463(eRF1_1)PF03464(eRF1_2)PF03465(eRF1_3) | 4 | VAL X 398THR X 399VAL P 614GLY P 597 | None | 1.15A | 2p2fA-4crnX:undetectable | 2p2fA-4crnX:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cta | CINA-LIKE PROTEIN (Thermusthermophilus) |
PF00994(MoCF_biosynth)PF02464(CinA) | 4 | VAL A 77THR A 78VAL A 9GLY A 10 | None | 1.02A | 2p2fA-4ctaA:2.5 | 2p2fA-4ctaA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4t | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXYLASE, ATPASESUBUNIT (Burkholderiaambifaria) |
PF02222(ATP-grasp) | 4 | VAL A 20THR A 81VAL A 107GLY A 104 | None | 0.98A | 2p2fA-4e4tA:2.8 | 2p2fA-4e4tA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e84 | D-BETA-D-HEPTOSE7-PHOSPHATE KINASE (Burkholderiacenocepacia) |
PF00294(PfkB) | 4 | VAL A 272THR A 271VAL A 300GLY A 298 | NoneNone K A 503 (-4.6A)ANP A 501 ( 4.8A) | 1.11A | 2p2fA-4e84A:2.3 | 2p2fA-4e84A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4esp | PROFILIN (Arachishypogaea) |
PF00235(Profilin) | 4 | VAL A 92THR A 93VAL A 82GLY A 77 | NoneNoneNoneEDO A 205 ( 3.6A) | 1.14A | 2p2fA-4espA:undetectable | 2p2fA-4espA:11.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hnn | DIHYDRODIPICOLINATESYNTHASE (Vitis vinifera) |
PF00701(DHDPS) | 4 | VAL A 89THR A 88VAL A 66GLY A 100 | None | 1.15A | 2p2fA-4hnnA:undetectable | 2p2fA-4hnnA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hzu | PREDICTED MEMBRANEPROTEIN (Lactobacillusbrevis) |
PF07155(ECF-ribofla_trS) | 4 | VAL S 20THR S 19VAL S 59GLY S 60 | None | 1.01A | 2p2fA-4hzuS:undetectable | 2p2fA-4hzuS:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ilf | THIOL:DISULFIDEINTERCHANGE PROTEINDSBC (Salmonellaenterica) |
PF10411(DsbC_N)PF13098(Thioredoxin_2) | 4 | VAL A 62THR A 63VAL A 36GLY A 49 | None | 1.14A | 2p2fA-4ilfA:undetectable | 2p2fA-4ilfA:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4izo | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXYLASE, ATPASESUBUNIT (Burkholderiathailandensis) |
PF02222(ATP-grasp) | 4 | VAL A 20THR A 81VAL A 107GLY A 104 | None | 1.01A | 2p2fA-4izoA:5.0 | 2p2fA-4izoA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mae | METHANOLDEHYDROGENASE (Methylacidiphilumfumariolicum) |
PF13360(PQQ_2) | 4 | VAL A 430VAL A 426GLY A 427TRP A 260 | NoneNoneNone15P A 603 (-4.9A) | 1.15A | 2p2fA-4maeA:undetectable | 2p2fA-4maeA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ml9 | UNCHARACTERIZEDPROTEIN (Sebaldellatermitidis) |
PF00977(His_biosynth) | 4 | VAL A 90THR A 91VAL A 106GLY A 107 | None | 1.07A | 2p2fA-4ml9A:4.2 | 2p2fA-4ml9A:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pb0 | AB53 LIGHT CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL L 132VAL L 159GLY L 158TRP L 148 | None | 1.11A | 2p2fA-4pb0L:undetectable | 2p2fA-4pb0L:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rcm | METHYLATEDRNA-BINDING PROTEIN1 (Saccharomycescerevisiae) |
PF04146(YTH) | 4 | VAL A 168VAL A 243GLY A 175TRP A 245 | NoneNoneUNX A 405 ( 4.2A)None | 1.11A | 2p2fA-4rcmA:undetectable | 2p2fA-4rcmA:14.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4e | THIOLASE (Sphaerobacterthermophilus) |
PF02803(Thiolase_C) | 4 | VAL A 101THR A 217VAL A 11GLY A 12 | None | 1.11A | 2p2fA-4u4eA:undetectable | 2p2fA-4u4eA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoz | BETA-GALACTOSIDASE (Bifidobacteriumanimalis) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | VAL A 593THR A 592VAL A 530GLY A 529 | PGE A1698 (-4.4A)NoneNoneNone | 1.12A | 2p2fA-4uozA:undetectable | 2p2fA-4uozA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ykn | PHOSPHATIDYLINOSITOL3-KINASE REGULATORYSUBUNITALPHA,PHOSPHATIDYLINOSITOL4,5-BISPHOSPHATE3-KINASE CATALYTICSUBUNIT ALPHAISOFORM FUSIONPROTEIN (Homo sapiens) |
PF00017(SH2)PF00454(PI3_PI4_kinase)PF00613(PI3Ka)PF00792(PI3K_C2)PF00794(PI3K_rbd)PF02192(PI3K_p85B)PF16454(PI3K_P85_iSH2) | 4 | THR A1679VAL A1461GLY A1460TRP A1446 | None | 1.08A | 2p2fA-4yknA:undetectable | 2p2fA-4yknA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ypn | LON PROTEASE (Meiothermustaiwanensis) |
PF00004(AAA) | 4 | VAL A 262VAL A 256GLY A 257TRP A 298 | None | 1.14A | 2p2fA-4ypnA:undetectable | 2p2fA-4ypnA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zm6 | N-ACETYL-BETA-DGLUCOSAMINIDASE (Rhizomucormiehei) |
PF00583(Acetyltransf_1)PF00933(Glyco_hydro_3) | 4 | VAL A 774THR A 771VAL A 828GLY A 827 | None | 1.03A | 2p2fA-4zm6A:undetectable | 2p2fA-4zm6A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoy | SQT1 (Chaetomiumthermophilum) |
PF00400(WD40) | 4 | VAL A 258THR A 257VAL A 216GLY A 210 | None | 1.11A | 2p2fA-4zoyA:undetectable | 2p2fA-4zoyA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5az4 | FLAGELLAR HOOKSUBUNIT PROTEIN (Campylobacterjejuni) |
PF07196(Flagellin_IN)PF07559(FlaE) | 4 | VAL A 335THR A 333VAL A 303GLY A 302 | None | 1.10A | 2p2fA-5az4A:undetectable | 2p2fA-5az4A:23.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c65 | SOLUTE CARRIERFAMILY 2,FACILITATED GLUCOSETRANSPORTER MEMBER 3 (Homo sapiens) |
PF00083(Sugar_tr) | 4 | VAL A 320THR A 319VAL A 163GLY A 161 | None | 1.00A | 2p2fA-5c65A:undetectable | 2p2fA-5c65A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dy1 | TETR FAMILYTRANSCRIPTIONALREGULATOR (Corynebacteriumglutamicum) |
PF00440(TetR_N) | 4 | VAL A 75THR A 74VAL A 114GLY A 115 | None | 0.89A | 2p2fA-5dy1A:undetectable | 2p2fA-5dy1A:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eyk | AURORA KINASE B-A (Xenopus laevis) |
PF00069(Pkinase) | 4 | VAL A 304VAL A 277GLY A 276TRP A 273 | None | 1.04A | 2p2fA-5eykA:undetectable | 2p2fA-5eykA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gq0 | EPITHIOSPECIFIERPROTEIN (Arabidopsisthaliana) |
no annotation | 4 | VAL B 109THR B 108VAL B 31GLY B 32 | None | 0.81A | 2p2fA-5gq0B:undetectable | 2p2fA-5gq0B:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gwo | PROBABLE PROTEINPHOSPHATASE 2C 50 (Oryza sativa) |
PF00481(PP2C) | 4 | VAL A 194THR A 195VAL A 199GLY A 200 | None | 0.90A | 2p2fA-5gwoA:undetectable | 2p2fA-5gwoA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h75 | MERSACIDINDECARBOXYLASE,IMMUNOGLOBULIN G-BINDINGPROTEIN A (Staphylococcusaureus;Bacillus sp.HIL-Y85/54728) |
PF02216(B)PF02441(Flavoprotein) | 4 | VAL A 111THR A 110VAL A 41GLY A 14 | None | 0.87A | 2p2fA-5h75A:3.1 | 2p2fA-5h75A:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hcc | COMPLEMENT C5 (Homo sapiens) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF07677(A2M_recep)PF07678(A2M_comp) | 4 | VAL A1248THR A1251VAL A1270TRP A1273 | None | 1.10A | 2p2fA-5hccA:undetectable | 2p2fA-5hccA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jpe | SERINE/THREONINE-PROTEIN PHOSPHATASE (Candidaalbicans) |
PF00149(Metallophos)PF16891(STPPase_N) | 4 | VAL A 429THR A 430VAL A 416GLY A 419 | None | 1.10A | 2p2fA-5jpeA:undetectable | 2p2fA-5jpeA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxl | FLAGELLAR HOOKPROTEIN FLGE (Campylobacterjejuni) |
PF00460(Flg_bb_rod)PF06429(Flg_bbr_C)PF07196(Flagellin_IN)PF07559(FlaE) | 4 | VAL A 337THR A 335VAL A 305GLY A 304 | None | 1.09A | 2p2fA-5jxlA:undetectable | 2p2fA-5jxlA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k0y | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT I (Oryctolaguscuniculus) |
PF00400(WD40) | 4 | VAL T 28THR T 27VAL T 309GLY T 303 | None | 1.13A | 2p2fA-5k0yT:undetectable | 2p2fA-5k0yT:18.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5k8f | ACETYL-COENZYME ASYNTHETASE (Cryptococcusneoformans) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 4 | THR A 336VAL A 411GLY A 412TRP A 439 | 6R9 A 704 ( 4.9A)ATP A 703 (-4.8A)ATP A 703 ( 3.4A)6R9 A 704 ( 3.5A) | 0.31A | 2p2fA-5k8fA:57.2 | 2p2fA-5k8fA:48.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m11 | IMMUNOREACTIVE 84KDANTIGEN PG93 (Porphyromonasgingivalis) |
no annotation | 4 | VAL A 750VAL A 707GLY A 706TRP A 740 | None | 0.99A | 2p2fA-5m11A:undetectable | 2p2fA-5m11A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n03 | GLUTACONATECOA-TRANSFERASEFAMILY, SUBUNIT B (Myxococcusxanthus) |
no annotation | 4 | VAL D 163THR D 165VAL D 132GLY D 131 | None | 1.01A | 2p2fA-5n03D:4.4 | 2p2fA-5n03D:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | VAL A1821THR A1822VAL A1785TRP A1758 | None | 1.03A | 2p2fA-5nugA:undetectable | 2p2fA-5nugA:9.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nz7 | CELLODEXTRINPHOSPHORYLASE (Ruminiclostridiumthermocellum) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 4 | VAL A 233THR A 232VAL A 165GLY A 169 | None | 1.10A | 2p2fA-5nz7A:undetectable | 2p2fA-5nz7A:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u09 | CANNABINOID RECEPTOR1,GLGA GLYCOGENSYNTHASE (Homo sapiens;Pyrococcusabyssi) |
PF00001(7tm_1)PF00534(Glycos_transf_1) | 4 | VAL A 282THR A 283VAL A 204GLY A 205 | None | 1.13A | 2p2fA-5u09A:2.9 | 2p2fA-5u09A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ui3 | DIHYDRODIPICOLINATESYNTHASE (Chlamydomonasreinhardtii) |
no annotation | 4 | VAL D 87THR D 86VAL D 64GLY D 98 | None | 1.12A | 2p2fA-5ui3D:undetectable | 2p2fA-5ui3D:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uwy | THIOREDOXINREDUCTASE (Streptococcuspyogenes) |
PF07992(Pyr_redox_2) | 4 | VAL A 27THR A 4VAL A 296GLY A 293 | None | 1.02A | 2p2fA-5uwyA:2.1 | 2p2fA-5uwyA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x41 | COBALT TRANSPORTPROTEIN CBIM (Rhodobactercapsulatus) |
no annotation | 4 | VAL M 154THR M 155VAL M 118GLY M 119 | None | 0.60A | 2p2fA-5x41M:undetectable | 2p2fA-5x41M:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgj | PHOSPHATIDYLINOSITOL4,5-BISPHOSPHATE3-KINASE CATALYTICSUBUNIT ALPHAISOFORM (Homo sapiens) |
no annotation | 4 | THR A 679VAL A 461GLY A 460TRP A 446 | None | 1.10A | 2p2fA-5xgjA:undetectable | 2p2fA-5xgjA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnw | ADENYLATE CYCLASEEXOY (Pseudomonasaeruginosa) |
no annotation | 4 | VAL A 332THR A 309VAL A 42GLY A 41 | None | 0.89A | 2p2fA-5xnwA:undetectable | 2p2fA-5xnwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6az6 | GNTR FAMILYTRANSCRIPTIONALREGULATOR (Streptococcusagalactiae) |
no annotation | 4 | VAL A 6THR A 9VAL A 40GLY A 41 | None | 1.12A | 2p2fA-6az6A:undetectable | 2p2fA-6az6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c08 | ANTIBODY FAB LIGHTCHAIN (Mus musculus) |
no annotation | 4 | VAL B 135VAL B 162GLY B 161TRP B 151 | None | 1.10A | 2p2fA-6c08B:undetectable | 2p2fA-6c08B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkh | ATP SYNTHASE SUBUNITBETA, CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 4 | VAL D 249THR D 252VAL D 100GLY D 115 | None | 1.08A | 2p2fA-6fkhD:undetectable | 2p2fA-6fkhD:undetectable |