SIMILAR PATTERNS OF AMINO ACIDS FOR 2OXT_A_SAMA300_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1biu HIV-1 INTEGRASE

(Human
immunodeficiency
virus 1) 		PF00665
(rve) 		3 SER A 153
HIS A  78
ASP A 202
 None
 0.85A 2oxtA-1biuA:
undetectable		 2oxtA-1biuA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ddk IMP-1 METALLO
BETA-LACTAMASE

(Pseudomonas
aeruginosa) 		PF00753
(Lactamase_B) 		3 SER A 179
HIS A  77
ASP A 109
 None
ZN  A 500 (-3.4A)
None
 0.72A 2oxtA-1ddkA:
undetectable		 2oxtA-1ddkA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fx2 RECEPTOR-TYPE
ADENYLATE CYCLASE
GRESAG 4.1

(Trypanosoma
brucei) 		PF00211
(Guanylate_cyc) 		3 SER A1013
HIS A 975
ASP A 923
 None
 0.84A 2oxtA-1fx2A:
undetectable		 2oxtA-1fx2A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ny9 TRANSCRIPTIONAL
ACTIVATOR TIPA-S

(Streptomyces
lividans) 		PF07739
(TipAS) 		3 SER A 186
HIS A 196
ASP A 168
 None
 0.82A 2oxtA-1ny9A:
undetectable		 2oxtA-1ny9A:
19.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		3 SER A  56
HIS A 110
ASP A 131
 SAH  A 887 ( 2.8A)
SO4  A 901 ( 3.9A)
SAH  A 887 ( 3.3A)
 0.47A 2oxtA-1r6aA:
39.3		 2oxtA-1r6aA:
48.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryy ALPHA-AMINO ACID
ESTER HYDROLASE

(Acetobacter
pasteurianus) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		3 SER A 537
HIS A 651
ASP A 453
 None
 0.85A 2oxtA-1ryyA:
undetectable		 2oxtA-1ryyA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sp8 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE

(Zea mays) 		PF00903
(Glyoxalase) 		3 SER A 423
HIS A 301
ASP A 218
 None
FE2  A 500 (-3.4A)
None
 0.78A 2oxtA-1sp8A:
undetectable		 2oxtA-1sp8A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sr4 CYTOLETHAL
DISTENDING TOXIN
PROTEIN B

([Haemophilus]
ducreyi) 		PF03372
(Exo_endo_phos) 		3 SER B 171
HIS B 160
ASP B 112
 None
BR  B 523 (-4.5A)
None
 0.40A 2oxtA-1sr4B:
2.1		 2oxtA-1sr4B:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svd RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT

(Halothiobacillus
neapolitanus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 SER A 314
HIS A 285
ASP A 196
 None
 0.58A 2oxtA-1svdA:
undetectable		 2oxtA-1svdA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ued P450 MONOOXYGENASE

(Amycolatopsis
orientalis) 		PF00067
(p450) 		3 SER A 290
HIS A  59
ASP A 307
 None
 0.64A 2oxtA-1uedA:
undetectable		 2oxtA-1uedA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z8l GLUTAMATE
CARBOXYPEPTIDASE II

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		3 SER A 615
HIS A 697
ASP A 683
 None
 0.80A 2oxtA-1z8lA:
undetectable		 2oxtA-1z8lA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cn1 CYTOSOLIC
5'-NUCLEOTIDASE III

(Homo sapiens) 		PF05822
(UMPH-1) 		3 SER A 228
HIS A  57
ASP A 158
 None
 0.83A 2oxtA-2cn1A:
undetectable		 2oxtA-2cn1A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy4 EPIDERMAL GROWTH
FACTOR RECEPTOR
PATHWAY SUBSTRATE
8-LIKE PROTEIN 1

(Mus musculus) 		PF08416
(PTB) 		3 SER A  92
HIS A  40
ASP A 133
 None
 0.77A 2oxtA-2cy4A:
undetectable		 2oxtA-2cy4A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE

(Streptomyces
antibioticus) 		PF00201
(UDPGT) 		3 SER A 333
HIS A 368
ASP A 372
 UDP  A1424 (-2.7A)
None
None
 0.72A 2oxtA-2iyaA:
2.4		 2oxtA-2iyaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kxp F-ACTIN-CAPPING
PROTEIN SUBUNIT BETA
ISOFORMS 1 AND 2

(Gallus gallus) 		PF01115
(F_actin_cap_B) 		3 SER B 390
HIS B 509
ASP B 505
 None
 0.78A 2oxtA-2kxpB:
undetectable		 2oxtA-2kxpB:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o56 PUTATIVE MANDELATE
RACEMASE

(Salmonella
enterica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 SER A 124
HIS A 345
ASP A 294
 None
 0.76A 2oxtA-2o56A:
undetectable		 2oxtA-2o56A:
21.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oxt NUCLEOSIDE-2'-O-METH
YLTRANSFERASE

(Meaban virus) 		PF01728
(FtsJ) 		3 SER A  57
HIS A 111
ASP A 132
 SAM  A 300 (-2.6A)
SAM  A 300 (-3.6A)
SAM  A 300 (-3.9A)
 0.01A 2oxtA-2oxtA:
48.9		 2oxtA-2oxtA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2px5 GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)]

(Murray Valley
encephalitis
virus) 		PF01728
(FtsJ) 		3 SER A  56
HIS A 110
ASP A 131
 SAH  A 500 (-2.5A)
SAH  A 500 (-3.9A)
SAH  A 500 (-3.5A)
 0.34A 2oxtA-2px5A:
39.6		 2oxtA-2px5A:
51.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7d RIBONUCLEASE II
FAMILY PROTEIN

(Deinococcus
radiodurans) 		PF00773
(RNB) 		3 SER A  25
HIS A  41
ASP A  51
 None
 0.84A 2oxtA-2r7dA:
undetectable		 2oxtA-2r7dA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5w KINESIN HEAVY CHAIN

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		3 SER A 208
HIS A 100
ASP A 108
 None
ADP  A 600 (-3.6A)
None
 0.68A 2oxtA-2y5wA:
undetectable		 2oxtA-2y5wA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		3 SER A 499
HIS A 129
ASP A 151
 None
None
CA  A1525 (-2.4A)
 0.65A 2oxtA-2yeqA:
undetectable		 2oxtA-2yeqA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a8p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 2

(Mus musculus) 		PF00169
(PH) 		3 SER A 715
HIS A 734
ASP A 594
 None
 0.74A 2oxtA-3a8pA:
undetectable		 2oxtA-3a8pA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brk GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE

(Agrobacterium
tumefaciens) 		PF00483
(NTP_transferase) 		3 SER X 363
HIS X  76
ASP X  82
 None
 0.83A 2oxtA-3brkX:
undetectable		 2oxtA-3brkX:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8v PUTATIVE
ACETYLTRANSFERASE

(Desulfovibrio
alaskensis) 		no annotation 3 SER A  77
HIS A  55
ASP A 107
 None
 0.86A 2oxtA-3c8vA:
undetectable		 2oxtA-3c8vA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c9f 5'-NUCLEOTIDASE

(Candida
albicans) 		PF00149
(Metallophos) 		3 SER A  98
HIS A  42
ASP A 393
 None
 0.79A 2oxtA-3c9fA:
undetectable		 2oxtA-3c9fA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cn7 CARBOXYLESTERASE

(Pseudomonas
aeruginosa) 		PF02230
(Abhydrolase_2) 		3 SER A  65
HIS A 121
ASP A 145
 None
 0.67A 2oxtA-3cn7A:
2.2		 2oxtA-3cn7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cob KINESIN HEAVY
CHAIN-LIKE PROTEIN

(Solanum
tuberosum) 		PF00225
(Kinesin) 		3 SER A1094
HIS A1090
ASP A1022
 None
 0.74A 2oxtA-3cobA:
undetectable		 2oxtA-3cobA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfy MUCONATE
CYCLOISOMERASE

(Thermotoga
maritima) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 SER A  52
HIS A  21
ASP A 169
 None
 0.85A 2oxtA-3dfyA:
undetectable		 2oxtA-3dfyA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE

(Bifidobacterium
adolescentis) 		PF02811
(PHP) 		3 SER A  62
HIS A  42
ASP A 278
 None
 0.70A 2oxtA-3e0fA:
undetectable		 2oxtA-3e0fA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5z PUTATIVE
GLUCONOLACTONASE

(Deinococcus
radiodurans) 		PF08450
(SGL) 		3 SER A 104
HIS A  87
ASP A 138
 None
 0.84A 2oxtA-3e5zA:
undetectable		 2oxtA-3e5zA:
18.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3evc RNA-DIRECTED RNA
POLYMERASE NS5

(Yellow fever
virus) 		PF01728
(FtsJ) 		3 SER A  56
HIS A 110
ASP A 131
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
 0.52A 2oxtA-3evcA:
39.8		 2oxtA-3evcA:
48.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgb UNCHARACTERIZED
PROTEIN Q89ZH8_BACTN

(Bacteroides
thetaiotaomicron) 		PF10282
(Lactonase) 		3 SER A  75
HIS A 178
ASP A 170
 None
 0.85A 2oxtA-3fgbA:
undetectable		 2oxtA-3fgbA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpz THIAZOLE
BIOSYNTHETIC ENZYME

(Saccharomyces
cerevisiae) 		PF01946
(Thi4) 		3 SER A  79
HIS A 123
ASP A 138
 None
 0.75A 2oxtA-3fpzA:
undetectable		 2oxtA-3fpzA:
23.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gcz POLYPROTEIN

(Yokose virus) 		PF01728
(FtsJ) 		3 SER A  56
HIS A 110
ASP A 131
 SAM  A4633 (-2.7A)
SAM  A4633 (-3.5A)
SAM  A4633 (-3.7A)
 0.28A 2oxtA-3gczA:
40.6		 2oxtA-3gczA:
49.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwi MAGNESIUM-TRANSPORTI
NG ATPASE, P-TYPE 1

(Escherichia
coli) 		PF13246
(Cation_ATPase) 		3 SER A 432
HIS A 388
ASP A 390
 None
 0.81A 2oxtA-3gwiA:
undetectable		 2oxtA-3gwiA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn7 UDP-N-ACETYLMURAMATE
-L-ALANINE LIGASE

(Psychrobacter
arcticus) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		3 SER A 191
HIS A 377
ASP A 209
 None
 0.81A 2oxtA-3hn7A:
undetectable		 2oxtA-3hn7A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpc SNX5 PROTEIN

(Rattus
norvegicus) 		PF00787
(PX) 		3 SER X  30
HIS X 153
ASP X  84
 None
 0.82A 2oxtA-3hpcX:
undetectable		 2oxtA-3hpcX:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iac GLUCURONATE
ISOMERASE

(Salmonella
enterica) 		PF02614
(UxaC) 		3 SER A  67
HIS A  59
ASP A 414
 None
 0.74A 2oxtA-3iacA:
undetectable		 2oxtA-3iacA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuk UNCHARACTERIZED
PROTEIN

(Paenarthrobacter
aurescens) 		PF05960
(DUF885) 		3 SER A 541
HIS A 392
ASP A 316
 None
 0.78A 2oxtA-3iukA:
undetectable		 2oxtA-3iukA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq0 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 SER A 212
HIS A 279
ASP A 388
 None
 0.86A 2oxtA-3jq0A:
undetectable		 2oxtA-3jq0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jro FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12110
(Nup96) 		3 SER A 121
HIS A  52
ASP A  30
 None
 0.83A 2oxtA-3jroA:
undetectable		 2oxtA-3jroA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkl PROBABLE CHAPERONE
PROTEIN HSP33

(Saccharomyces
cerevisiae) 		no annotation 3 SER A 223
HIS A 108
ASP A 176
 None
 0.85A 2oxtA-3kklA:
2.6		 2oxtA-3kklA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3max HISTONE DEACETYLASE
2

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		3 SER A 353
HIS A 286
ASP A 179
 None
None
CA  A 380 (-3.3A)
 0.82A 2oxtA-3maxA:
3.2		 2oxtA-3maxA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mca ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
PROTEIN DOM34

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		3 SER B 360
HIS A 542
ASP B 288
 None
 0.81A 2oxtA-3mcaB:
undetectable		 2oxtA-3mcaB:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p5m ENOYL-COA
HYDRATASE/ISOMERASE

(Mycobacterium
avium) 		PF00378
(ECH_1) 		3 SER A  46
HIS A  37
ASP A  18
 None
 0.83A 2oxtA-3p5mA:
undetectable		 2oxtA-3p5mA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9o EXOTOXIN A

(Vibrio cholerae) 		PF09009
(Exotox-A_cataly)
PF09101
(Exotox-A_bind)
PF09102
(Exotox-A_target) 		3 SER A 148
HIS A 275
ASP A 297
 None
 0.78A 2oxtA-3q9oA:
undetectable		 2oxtA-3q9oA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swg UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Aquifex
aeolicus) 		PF00275
(EPSP_synthase) 		3 SER A 321
HIS A 339
ASP A 397
 None
 0.67A 2oxtA-3swgA:
undetectable		 2oxtA-3swgA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sxp ADP-L-GLYCERO-D-MANN
OHEPTOSE-6-EPIMERASE

(Helicobacter
pylori) 		PF01370
(Epimerase) 		3 SER A 128
HIS A  96
ASP A  43
 None
None
NAD  A2402 (-2.6A)
 0.78A 2oxtA-3sxpA:
5.0		 2oxtA-3sxpA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsr RIBONUCLEASE
PANCREATIC

(Mus musculus) 		PF00074
(RnaseA) 		3 SER A  20
HIS A  13
ASP A 122
 None
 0.68A 2oxtA-3tsrA:
undetectable		 2oxtA-3tsrA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugv ENOLASE

(alpha
proteobacterium
BAL199) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 SER A  91
HIS A  68
ASP A  39
 None
 0.82A 2oxtA-3ugvA:
undetectable		 2oxtA-3ugvA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vex O-CARBAMOYLTRANSFERA
SE TOBZ

(Streptoalloteichus
tenebrarius) 		PF02543
(Carbam_trans_N)
PF16861
(Carbam_trans_C) 		3 SER A 175
HIS A 194
ASP A 494
 None
 0.86A 2oxtA-3vexA:
undetectable		 2oxtA-3vexA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cj0 ENDOGLUCANASE D

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		3 SER A 331
HIS A 269
ASP A 198
 None
 0.77A 2oxtA-4cj0A:
undetectable		 2oxtA-4cj0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dte SERPIN PEPTIDASE
INHIBITOR, CLADE E
(NEXIN, PLASMINOGEN
ACTIVATOR INHIBITOR
TYPE 1), MEMBER 1

(Danio rerio) 		PF00079
(Serpin) 		3 SER A  36
HIS A 356
ASP A  81
 None
 0.66A 2oxtA-4dteA:
undetectable		 2oxtA-4dteA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1s 5'-NUCLEOTIDASE

(Homo sapiens) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		3 SER A 549
HIS A 456
ASP A 485
 None
 0.85A 2oxtA-4h1sA:
undetectable		 2oxtA-4h1sA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hcx ISOCITRATE
DEHYDROGENASE [NADP]

(Mycobacterium
tuberculosis) 		PF00180
(Iso_dh) 		3 SER A 199
HIS A 251
ASP A 255
 None
 0.72A 2oxtA-4hcxA:
undetectable		 2oxtA-4hcxA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcm CYCLODEXTRIN
GLUCANOTRANSFERASE

([Bacillus]
clarkii) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		3 SER A 180
HIS A 261
ASP A 303
 None
 0.52A 2oxtA-4jcmA:
undetectable		 2oxtA-4jcmA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2p T-LYMPHOMA INVASION
AND
METASTASIS-INDUCING
PROTEIN 1

(Homo sapiens) 		PF00169
(PH) 		3 SER A 644
HIS A 663
ASP A 523
 None
 0.70A 2oxtA-4k2pA:
undetectable		 2oxtA-4k2pA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6m POLYPROTEIN

(Japanese
encephalitis
virus) 		PF00972
(Flavi_NS5)
PF01728
(FtsJ) 		3 SER A  56
HIS A 110
ASP A 131
 SAH  A1001 (-2.8A)
SAH  A1001 ( 3.6A)
SAH  A1001 (-3.7A)
 0.39A 2oxtA-4k6mA:
39.4		 2oxtA-4k6mA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq6 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

([Candida]
glabrata) 		PF00885
(DMRL_synthase) 		3 SER A 103
HIS A 149
ASP A 141
 None
 0.83A 2oxtA-4kq6A:
undetectable		 2oxtA-4kq6A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ly4 PEPTIDOGLYCAN
DEACETYLASE

(Helicobacter
pylori) 		PF01522
(Polysacc_deac_1) 		3 SER A 251
HIS A  86
ASP A 146
 None
ZN  A 301 (-3.4A)
None
 0.81A 2oxtA-4ly4A:
undetectable		 2oxtA-4ly4A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Pisum sativum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 SER A 321
HIS A 292
ASP A 203
 None
None
RUB  A 501 (-3.2A)
 0.71A 2oxtA-4mkvA:
undetectable		 2oxtA-4mkvA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ol8 REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Saccharomyces
cerevisiae) 		PF00078
(RVT_1) 		3 SER A 139
HIS A 417
ASP A 449
 None
 0.74A 2oxtA-4ol8A:
undetectable		 2oxtA-4ol8A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p17 RABGAP/TBC PROTEIN

(Chlamydomonas
reinhardtii) 		PF00566
(RabGAP-TBC) 		3 SER A 236
HIS A 113
ASP A 106
 None
 0.83A 2oxtA-4p17A:
undetectable		 2oxtA-4p17A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9t NUCLEOPORIN NUP133

(Vanderwaltozyma
polyspora) 		PF08801
(Nucleoporin_N) 		3 SER A 146
HIS A 413
ASP A 352
 None
 0.80A 2oxtA-4q9tA:
undetectable		 2oxtA-4q9tA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE
DNA-DIRECTED RNA
POLYMERASE

(Thermococcus
kodakarensis;
Thermococcus
kodakarensis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 SER B 846
HIS B 999
ASP A 463
 None
None
MG  A1001 (-3.0A)
 0.82A 2oxtA-4qiwB:
undetectable		 2oxtA-4qiwB:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qx8 LYSINE-SPECIFIC
DEMETHYLASE 2A

(Mus musculus) 		PF02373
(JmjC) 		3 SER A 250
HIS A 239
ASP A 264
 None
 0.78A 2oxtA-4qx8A:
undetectable		 2oxtA-4qx8A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2h STIV B204 ATPASE

(Sulfolobus
turreted
icosahedral
virus 1) 		no annotation 3 SER A  15
HIS A 201
ASP A 192
 None
 0.67A 2oxtA-4r2hA:
2.3		 2oxtA-4r2hA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rer 5'-AMP-ACTIVATED
PROTEIN KINASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00571
(CBS) 		3 SER G 137
HIS G 169
ASP G 317
 None
None
AMP  G 403 (-2.9A)
 0.85A 2oxtA-4rerG:
undetectable		 2oxtA-4rerG:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rpd CAPSID PROTEIN

(Norwalk virus) 		PF08435
(Calici_coat_C) 		3 SER A 356
HIS A 299
ASP A 375
 None
 0.84A 2oxtA-4rpdA:
undetectable		 2oxtA-4rpdA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvh D-MYCAROSE
3-C-METHYLTRANSFERAS
E

(Streptomyces
argillaceus) 		PF08421
(Methyltransf_13)
PF08484
(Methyltransf_14)
PF13489
(Methyltransf_23) 		3 SER A 234
HIS A 226
ASP A 220
 None
3YN  A 503 (-4.5A)
None
 0.76A 2oxtA-4rvhA:
6.8		 2oxtA-4rvhA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmu RECQ

(Cronobacter
sakazakii) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF09382
(RQC)
PF16124
(RecQ_Zn_bind) 		3 SER A 277
HIS A 267
ASP A 251
 None
 0.85A 2oxtA-4tmuA:
2.3		 2oxtA-4tmuA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uad IMPORTIN SUBUNIT
ALPHA-7

(Homo sapiens) 		PF00514
(Arm)
PF16186
(Arm_3) 		3 SER A 347
HIS A 305
ASP A 267
 None
 0.76A 2oxtA-4uadA:
undetectable		 2oxtA-4uadA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ubq BETA-LACTAMASE

(Acinetobacter
baumannii) 		no annotation 3 SER A 180
HIS A  78
ASP A 110
 None
ZN  A 301 (-3.4A)
None
 0.53A 2oxtA-4ubqA:
undetectable		 2oxtA-4ubqA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa) 		PF01425
(Amidase) 		3 SER A 152
HIS A  76
ASP A 102
 None
 0.74A 2oxtA-4wj3A:
undetectable		 2oxtA-4wj3A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynu GLUCOSE OXIDASE,
PUTATIVE

(Aspergillus
flavus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		3 SER A 257
HIS A 228
ASP A   7
 None
 0.78A 2oxtA-4ynuA:
undetectable		 2oxtA-4ynuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yuf CORB

(Corallococcus
coralloides) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		3 SER A 189
HIS A 264
ASP A 149
 None
 0.82A 2oxtA-4yufA:
undetectable		 2oxtA-4yufA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afd N-ACETYLNEURAMINATE
LYASE

(Aliivibrio
salmonicida) 		PF00701
(DHDPS) 		3 SER A 221
HIS A 300
ASP A 265
 None
 0.75A 2oxtA-5afdA:
undetectable		 2oxtA-5afdA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3r IMP-18

(Pseudomonas
aeruginosa) 		no annotation 3 SER A 197
HIS A  95
ASP A 127
 None
ZN  A2001 ( 3.4A)
None
 0.85A 2oxtA-5b3rA:
undetectable		 2oxtA-5b3rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bo6 SIA-ALPHA-2,3-GAL-BE
TA-1,4-GLCNAC-R:ALPH
A
2,8-SIALYLTRANSFERAS
E

(Homo sapiens) 		PF00777
(Glyco_transf_29) 		3 SER A 174
HIS A 317
ASP A 184
 None
FUC  A 408 (-4.7A)
None
 0.82A 2oxtA-5bo6A:
undetectable		 2oxtA-5bo6A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5h 2-SUCCINYLBENZOATE--
COA LIGASE

(Escherichia
coli) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 SER A 276
HIS A 220
ASP A 174
 4YB  A 502 (-3.9A)
None
None
 0.82A 2oxtA-5c5hA:
2.3		 2oxtA-5c5hA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chc DMSO REDUCTASE
FAMILY TYPE II
ENZYME,
MOLYBDOPTERIN
SUBUNIT

(Azospira oryzae) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 SER A 146
HIS A  32
ASP A  82
 MD1  A1004 ( 4.7A)
SF4  A1001 (-3.3A)
NA  A1015 ( 4.9A)
 0.81A 2oxtA-5chcA:
undetectable		 2oxtA-5chcA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbb NUCLEASE S1

(Aspergillus
oryzae) 		PF02265
(S1-P1_nuclease) 		3 SER A 260
HIS A 145
ASP A  83
 None
ZN  A 403 ( 3.3A)
AMP  A 701 ( 2.6A)
 0.79A 2oxtA-5fbbA:
undetectable		 2oxtA-5fbbA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz SPINDLE POLE BODY
COMPONENT SPC98

(Saccharomyces
cerevisiae) 		PF04130
(Spc97_Spc98) 		3 SER B 737
HIS B 728
ASP B 722
 None
 0.67A 2oxtA-5flzB:
undetectable		 2oxtA-5flzB:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fzp DISPASE
AUTOLYSIS-INDUCING
PROTEIN

(Streptomyces
mobaraensis) 		no annotation 3 SER A 118
HIS A 135
ASP A 178
 None
 0.71A 2oxtA-5fzpA:
undetectable		 2oxtA-5fzpA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i33 ADENYLOSUCCINATE
SYNTHETASE

(Cryptococcus
neoformans) 		PF00709
(Adenylsucc_synt) 		3 SER A 247
HIS A 114
ASP A 111
 None
 0.84A 2oxtA-5i33A:
undetectable		 2oxtA-5i33A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2

(Zaire
ebolavirus;
Zaire
ebolavirus) 		PF01611
(Filo_glycop)
no annotation 		3 SER A  58
HIS A  39
ASP B 552
 None
 0.72A 2oxtA-5kenA:
undetectable		 2oxtA-5kenA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksp MITOCHONDRIAL RHO
GTPASE 1

(Homo sapiens) 		PF00071
(Ras) 		3 SER A 479
HIS A 474
ASP A 490
 None
 0.70A 2oxtA-5kspA:
2.9		 2oxtA-5kspA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdh MALATE DEHYDROGENASE

(Sus scrofa) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 SER A  27
HIS A 252
ASP A 158
 None
 0.70A 2oxtA-5mdhA:
4.8		 2oxtA-5mdhA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlq CDPS

(Nocardia
brasiliensis) 		no annotation 3 SER A  61
HIS A 186
ASP A 123
 None
CIT  A 301 (-3.8A)
None
 0.53A 2oxtA-5mlqA:
undetectable		 2oxtA-5mlqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN7

(Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF10602
(RPN7) 		3 SER R 196
HIS R 217
ASP R 183
 None
 0.80A 2oxtA-5mpdR:
undetectable		 2oxtA-5mpdR:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nju GENOME POLYPROTEIN

(Zika virus) 		no annotation 3 SER A  56
HIS A 110
ASP A 131
 SAH  A1001 (-2.6A)
SAH  A1001 (-4.0A)
SAH  A1001 (-3.9A)
 0.25A 2oxtA-5njuA:
38.8		 2oxtA-5njuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohs -

(-) 		no annotation 3 SER A 559
HIS A 484
ASP A 487
 None
None
NSQ  A 709 ( 4.8A)
 0.74A 2oxtA-5ohsA:
undetectable		 2oxtA-5ohsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5okl AFAMIN

(Homo sapiens) 		no annotation 3 SER A 242
HIS A 201
ASP A 451
 None
 0.72A 2oxtA-5oklA:
undetectable		 2oxtA-5oklA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t67 SUGAR 3-C-METHYL
TRANSFERASE

(Actinomadura
kijaniata) 		PF08421
(Methyltransf_13)
PF08484
(Methyltransf_14)
PF13489
(Methyltransf_23) 		3 SER A 233
HIS A 225
ASP A 219
 None
JHZ  A 503 (-4.1A)
None
 0.86A 2oxtA-5t67A:
6.5		 2oxtA-5t67A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Acinetobacter
baumannii) 		PF00275
(EPSP_synthase) 		3 SER A 258
HIS A 254
ASP A  69
 None
 0.65A 2oxtA-5u4hA:
undetectable		 2oxtA-5u4hA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uth THIOREDOXIN
REDUCTASE

(Mycolicibacterium
smegmatis) 		PF07992
(Pyr_redox_2) 		3 SER A  15
HIS A 105
ASP A 102
 FAD  A 400 (-3.6A)
SO4  A 402 (-3.6A)
None
 0.65A 2oxtA-5uthA:
undetectable		 2oxtA-5uthA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu3 SPECKLE TARGETED
PIP5K1A-REGULATED
POLY(A) POLYMERASE

(Homo sapiens) 		PF03828
(PAP_assoc) 		3 SER A 548
HIS A 391
ASP A 222
 None
 0.59A 2oxtA-5wu3A:
undetectable		 2oxtA-5wu3A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu6 SPECKLE TARGETED
PIP5K1A-REGULATED
POLY(A) POLYMERASE

(Homo sapiens) 		PF00076
(RRM_1)
PF03828
(PAP_assoc) 		3 SER A 548
HIS A 391
ASP A 222
 None
 0.59A 2oxtA-5wu6A:
undetectable		 2oxtA-5wu6A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0g PIRIN FAMILY PROTEIN

(Acinetobacter
baumannii) 		no annotation 3 SER A  45
HIS A  59
ASP A 191
 None
 0.78A 2oxtA-6d0gA:
undetectable		 2oxtA-6d0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN

(Homo sapiens) 		no annotation 3 SER A 492
HIS A 350
ASP A 314
 None
 0.84A 2oxtA-6ei1A:
undetectable		 2oxtA-6ei1A:
undetectable