SIMILAR PATTERNS OF AMINO ACIDS FOR 2OUZ_A_C3DA999_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1as4 | ANTICHYMOTRYPSIN (Homo sapiens) |
PF00079(Serpin) | 5 | LEU A 64LEU A 73ILE A 308GLY A 79LEU A 80 | None | 0.91A | 2ouzA-1as4A:0.0 | 2ouzA-1as4A:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbr | HYPOXANTHINE GUANINEXANTHINEPHOSPHORIBOSYLTRANSFERASE (Toxoplasmagondii) |
PF00156(Pribosyltran) | 5 | LEU A 175THR A 174LEU A 143LEU A 88LEU A 87 | None | 1.08A | 2ouzA-1dbrA:0.0 | 2ouzA-1dbrA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ehk | BA3-TYPECYTOCHROME-C OXIDASE (Thermusthermophilus) |
PF00115(COX1) | 5 | LEU A 222LEU A 202LEU A 546GLY A 551LEU A 553 | None | 1.08A | 2ouzA-1ehkA:0.0 | 2ouzA-1ehkA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ey2 | HOMOGENTISATE1,2-DIOXYGENASE (Homo sapiens) |
PF04209(HgmA) | 5 | LEU A 301THR A 302LEU A 131LEU A 201ILE A 317 | None | 1.00A | 2ouzA-1ey2A:undetectable | 2ouzA-1ey2A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gyd | ARABINANENDO-1,5-ALPHA-L-ARABINOSIDASE A (Cellvibriojaponicus) |
PF04616(Glyco_hydro_43) | 5 | LEU B 323LEU B 279LEU B 278GLY B 290LEU B 305 | None | 1.05A | 2ouzA-1gydB:undetectable | 2ouzA-1gydB:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7j | PROTEIN YCIO (Escherichiacoli) |
PF01300(Sua5_yciO_yrdC) | 5 | LEU A 101THR A 118LEU A 111LEU A 67LEU A 75 | None | 1.07A | 2ouzA-1k7jA:0.0 | 2ouzA-1k7jA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1luj | CATENIN BETA-1 (Homo sapiens) |
PF00514(Arm) | 5 | THR A 297LEU A 324ILE A 315GLY A 320LEU A 286 | None | 0.97A | 2ouzA-1lujA:0.3 | 2ouzA-1lujA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m2v | PROTEIN TRANSPORTPROTEIN SEC24 (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | LEU B 406THR B 405LEU B 333LEU B 330ILE B 345 | None | 0.95A | 2ouzA-1m2vB:undetectable | 2ouzA-1m2vB:13.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | MET A 343LEU A 346LEU A 402ILE A 424GLY A 521HIS A 524 | EST A 1 ( 4.0A)EST A 1 (-4.4A)NoneEST A 1 ( 4.5A)EST A 1 ( 4.1A)EST A 1 (-3.8A) | 1.47A | 2ouzA-1pcgA:31.8 | 2ouzA-1pcgA:98.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 12 | MET A 343LEU A 346THR A 347LEU A 354LEU A 384LEU A 387MET A 388LEU A 391ILE A 424GLY A 521HIS A 524LEU A 525 | EST A 1 ( 4.0A)EST A 1 (-4.4A)NoneNoneNoneEST A 1 (-4.0A)NoneEST A 1 ( 3.9A)EST A 1 ( 4.5A)EST A 1 ( 4.1A)EST A 1 (-3.8A)EST A 1 (-3.6A) | 0.74A | 2ouzA-1pcgA:31.8 | 2ouzA-1pcgA:98.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qun | PAPD-LIKE CHAPERONEFIMC (Escherichiacoli) |
PF00345(PapD_N)PF02753(PapD_C) | 5 | THR A 189LEU A 166LEU A 142ILE A 185LEU A 131 | None | 1.04A | 2ouzA-1qunA:undetectable | 2ouzA-1qunA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1srv | PROTEIN (GROEL(HSP60 CLASS)) (Thermusthermophilus) |
PF00118(Cpn60_TCP1) | 5 | LEU A 314THR A 313LEU A 309LEU A 221GLY A 298 | None | 1.05A | 2ouzA-1srvA:undetectable | 2ouzA-1srvA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqh | CARBOXYLESTERASEPRECURSOR (Geobacillusstearothermophilus) |
PF12146(Hydrolase_4) | 5 | THR A 45LEU A 20LEU A 21GLY A 76LEU A 80 | None | 1.03A | 2ouzA-1tqhA:0.0 | 2ouzA-1tqhA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ur1 | ENDOXYLANASE (Cellvibriomixtus) |
PF00331(Glyco_hydro_10) | 5 | LEU A 314LEU A 263ILE A 230GLY A 232LEU A 234 | None | 0.88A | 2ouzA-1ur1A:undetectable | 2ouzA-1ur1A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ur1 | ENDOXYLANASE (Cellvibriomixtus) |
PF00331(Glyco_hydro_10) | 5 | LEU A 365LEU A 263ILE A 230GLY A 232LEU A 234 | None | 1.08A | 2ouzA-1ur1A:undetectable | 2ouzA-1ur1A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcg | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Thermusthermophilus) |
PF01070(FMN_dh) | 5 | LEU A 57LEU A 282LEU A 281GLY A 271LEU A 310 | None | 1.00A | 2ouzA-1vcgA:undetectable | 2ouzA-1vcgA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcg | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Thermusthermophilus) |
PF01070(FMN_dh) | 5 | LEU A 177LEU A 174LEU A 170GLY A 133LEU A 137 | None | 0.89A | 2ouzA-1vcgA:undetectable | 2ouzA-1vcgA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wmu | HEMOGLOBIN D ALPHACHAIN (Aldabrachelysgigantea) |
PF00042(Globin) | 5 | LEU A 9LEU A 129GLY A 110HIS A 112LEU A 113 | None | 0.93A | 2ouzA-1wmuA:undetectable | 2ouzA-1wmuA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yrz | XYLANBETA-1,4-XYLOSIDASE (Bacillushalodurans) |
PF04616(Glyco_hydro_43) | 5 | LEU A1202LEU A1216GLY A1251HIS A1265LEU A1263 | None | 1.02A | 2ouzA-1yrzA:undetectable | 2ouzA-1yrzA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ayz | SENSOR KINASEPROTEIN RCSC (Escherichiacoli) |
PF00072(Response_reg) | 5 | THR A 935LEU A 929LEU A 844LEU A 847LEU A 873 | None | 1.06A | 2ouzA-2ayzA:undetectable | 2ouzA-2ayzA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bap | DIAPHANOUS PROTEINHOMOLOG 1 (Mus musculus) |
no annotation | 5 | LEU B 179LEU B 159LEU B 163ILE B 208LEU B 143 | None | 1.00A | 2ouzA-2bapB:undetectable | 2ouzA-2bapB:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ch1 | 3-HYDROXYKYNURENINETRANSAMINASE (Anophelesgambiae) |
PF00266(Aminotran_5) | 5 | LEU A 97LEU A 89LEU A 149ILE A 168HIS A 172 | None | 1.06A | 2ouzA-2ch1A:undetectable | 2ouzA-2ch1A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fk4 | PROTEIN E6 (Alphapapillomavirus9) |
PF00518(E6) | 5 | LEU A 19LEU A 22LEU A 23HIS A 41LEU A 42 | None | 1.02A | 2ouzA-2fk4A:undetectable | 2ouzA-2fk4A:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h5g | DELTA1-PYRROLINE-5-CARBOXYLATE SYNTHETASE (Homo sapiens) |
PF00171(Aldedh) | 5 | LEU A 487LEU A 433LEU A 392ILE A 515LEU A 428 | None | 1.04A | 2ouzA-2h5gA:undetectable | 2ouzA-2h5gA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h5x | HOLLIDAY JUNCTIONATP-DEPENDENT DNAHELICASE RUVA (Mycobacteriumtuberculosis) |
PF01330(RuvA_N)PF07499(RuvA_C)PF14520(HHH_5) | 5 | THR A 73LEU A 97LEU A 89ILE A 115LEU A 101 | None | 1.04A | 2ouzA-2h5xA:undetectable | 2ouzA-2h5xA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nra | PI PROTEIN (Escherichiacoli) |
PF01051(Rep_3) | 5 | LEU C 40LEU C 84LEU C 25ILE C 141LEU C 135 | None | 0.87A | 2ouzA-2nraC:undetectable | 2ouzA-2nraC:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o78 | PUTATIVE HISTIDINEAMMONIA-LYASE (Rhodobactersphaeroides) |
PF00221(Lyase_aromatic) | 5 | LEU A 229THR A 230LEU A 237LEU A 380ILE A 459 | None | 1.07A | 2ouzA-2o78A:undetectable | 2ouzA-2o78A:19.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | MET A 343LEU A 346LEU A 402ILE A 424GLY A 521HIS A 524 | EST A 596 (-4.8A)EST A 596 (-4.4A)NoneEST A 596 ( 4.7A)EST A 596 ( 4.0A)EST A 596 (-4.2A) | 1.44A | 2ouzA-2ocfA:30.1 | 2ouzA-2ocfA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 10 | MET A 343LEU A 346THR A 347LEU A 354LEU A 384LEU A 387MET A 388LEU A 391ILE A 424GLY A 521 | EST A 596 (-4.8A)EST A 596 (-4.4A)NoneNoneNoneEST A 596 ( 4.2A)NoneEST A 596 ( 4.6A)EST A 596 ( 4.7A)EST A 596 ( 4.0A) | 0.64A | 2ouzA-2ocfA:30.1 | 2ouzA-2ocfA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 10 | MET A 343LEU A 346THR A 347LEU A 384LEU A 387MET A 388LEU A 391GLY A 521HIS A 524LEU A 525 | EST A 596 (-4.8A)EST A 596 (-4.4A)NoneNoneEST A 596 ( 4.2A)NoneEST A 596 ( 4.6A)EST A 596 ( 4.0A)EST A 596 (-4.2A)EST A 596 (-3.6A) | 0.74A | 2ouzA-2ocfA:30.1 | 2ouzA-2ocfA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 10 | MET A 343LEU A 346THR A 347LEU A 384LEU A 387MET A 388LEU A 391ILE A 424GLY A 521HIS A 524 | EST A 596 (-4.8A)EST A 596 (-4.4A)NoneNoneEST A 596 ( 4.2A)NoneEST A 596 ( 4.6A)EST A 596 ( 4.7A)EST A 596 ( 4.0A)EST A 596 (-4.2A) | 0.58A | 2ouzA-2ocfA:30.1 | 2ouzA-2ocfA:99.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oda | HYPOTHETICAL PROTEINPSPTO_2114 (Pseudomonassyringae groupgenomosp. 3) |
no annotation | 5 | LEU A 126THR A 128LEU A 9ILE A 58GLY A 12 | None | 1.04A | 2ouzA-2odaA:undetectable | 2ouzA-2odaA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqq | PUTATIVETRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
PF00027(cNMP_binding) | 6 | LEU A 113LEU A 104LEU A 22GLY A 105HIS A 106LEU A 83 | None | 1.44A | 2ouzA-2pqqA:undetectable | 2ouzA-2pqqA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyx | TRYPTOPHANHALOGENASE (Shewanellafrigidimarina) |
PF04820(Trp_halogenase) | 5 | LEU A 374THR A 370LEU A 24ILE A 11GLY A 18 | NoneNonePG4 A 529 (-3.8A)NoneNone | 0.86A | 2ouzA-2pyxA:undetectable | 2ouzA-2pyxA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rsp | RSV PROTEASE (Rous sarcomavirus) |
PF00077(RVP) | 6 | LEU A 119LEU A 109LEU A 36LEU A 12ILE A 32LEU A 82 | None | 1.45A | 2ouzA-2rspA:undetectable | 2ouzA-2rspA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxo | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Homo sapiens) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 5 | LEU A 256LEU A 422LEU A 411ILE A 227LEU A 426 | None | 1.05A | 2ouzA-2vxoA:undetectable | 2ouzA-2vxoA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wch | GENERALODORANT-BINDINGPROTEIN 1 (Bombyx mori) |
PF01395(PBP_GOBP) | 5 | MET A 5THR A 9LEU A 16LEU A 61ILE A 94 | NoneB7M A1145 ( 4.1A)NoneB7M A1145 ( 4.7A)B7M A1145 ( 4.5A) | 0.86A | 2ouzA-2wchA:undetectable | 2ouzA-2wchA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu8 | GLUCOSE-6-PHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00342(PGI) | 5 | THR A 478LEU A 51LEU A 485ILE A 301GLY A 49 | None | 0.89A | 2ouzA-2wu8A:undetectable | 2ouzA-2wu8A:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | LEU A 551LEU A 611LEU A 578GLY A 610HIS A 609 | None | 1.08A | 2ouzA-2xaxA:undetectable | 2ouzA-2xaxA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xym | RNA-DIRECTED RNAPOLYMERASE (Hepacivirus C) |
PF00998(RdRP_3) | 5 | LEU A 392LEU A 425MET A 426ILE A 463HIS A 467 | None | 1.08A | 2ouzA-2xymA:undetectable | 2ouzA-2xymA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z63 | TOLL-LIKE RECEPTOR4, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF11921(DUF3439)PF13516(LRR_6)PF13855(LRR_8) | 5 | MET A 527LEU A 495LEU A 519ILE A 539LEU A 488 | None | 1.07A | 2ouzA-2z63A:undetectable | 2ouzA-2z63A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z6g | B-CATENIN (Danio rerio) |
PF00514(Arm) | 5 | THR A 296LEU A 323ILE A 314GLY A 319LEU A 285 | None | 1.00A | 2ouzA-2z6gA:undetectable | 2ouzA-2z6gA:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z6h | CATENIN BETA-1 (Homo sapiens) |
PF00514(Arm) | 5 | THR A 297LEU A 324ILE A 315GLY A 320LEU A 286 | None | 0.94A | 2ouzA-2z6hA:undetectable | 2ouzA-2z6hA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b12 | FLUOROACETATEDEHALOGENASE (Burkholderiasp.) |
PF00561(Abhydrolase_1) | 5 | MET A 40LEU A 29LEU A 28GLY A 107HIS A 103 | None | 1.06A | 2ouzA-3b12A:undetectable | 2ouzA-3b12A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b13 | DEDICATOR OFCYTOKINESIS PROTEIN2 (Homo sapiens) |
PF06920(DHR-2) | 5 | LEU A1244LEU A1479LEU A1208LEU A1227ILE A1221 | None | 0.92A | 2ouzA-3b13A:undetectable | 2ouzA-3b13A:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8u | PURR TRANSCRIPTIONALREGULATOR (Vibrioparahaemolyticus) |
PF13377(Peripla_BP_3) | 5 | LEU A 272LEU A 249LEU A 243GLY A 191LEU A 252 | None | 1.07A | 2ouzA-3d8uA:undetectable | 2ouzA-3d8uA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0x | LIPASE-ESTERASERELATED PROTEIN (Clostridiumacetobutylicum) |
PF12146(Hydrolase_4) | 5 | LEU A 158THR A 157LEU A 150LEU A 227HIS A 20 | OXE A 243 (-4.7A)NoneNoneNoneNone | 1.07A | 2ouzA-3e0xA:undetectable | 2ouzA-3e0xA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h68 | SERINE/THREONINE-PROTEIN PHOSPHATASE 5 (Homo sapiens) |
PF00149(Metallophos)PF08321(PPP5) | 5 | THR A 306LEU A 340LEU A 220HIS A 352LEU A 385 | NoneNoneNone ZN A 500 ( 3.2A)None | 1.07A | 2ouzA-3h68A:undetectable | 2ouzA-3h68A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhc | INTERLEUKIN-28B (Homo sapiens) |
PF15177(IL28A) | 5 | LEU A 69LEU A 125LEU A 61ILE A 96LEU A 148 | None | 1.06A | 2ouzA-3hhcA:undetectable | 2ouzA-3hhcA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hr0 | COG4 (Homo sapiens) |
PF04437(RINT1_TIP1) | 5 | LEU A 675LEU A 678MET A 679LEU A 682LEU A 545 | None | 0.72A | 2ouzA-3hr0A:undetectable | 2ouzA-3hr0A:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3t | UBIQUITINCARBOXYL-TERMINALHYDROLASE 21 (Homo sapiens) |
PF00443(UCH) | 5 | LEU A 507LEU A 459LEU A 416LEU A 484LEU A 463 | None | 0.95A | 2ouzA-3i3tA:undetectable | 2ouzA-3i3tA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9u | HEME OXYGENASE 1 (Rattusnorvegicus) |
PF01126(Heme_oxygenase) | 5 | LEU A 128LEU A 77LEU A 13LEU A 189LEU A 17 | None | 1.06A | 2ouzA-3i9uA:2.7 | 2ouzA-3i9uA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iu1 | GLYCYLPEPTIDEN-TETRADECANOYLTRANSFERASE 1 (Homo sapiens) |
PF01233(NMT)PF02799(NMT_C) | 5 | LEU A 176LEU A 161LEU A 201GLY A 213LEU A 222 | None | 1.06A | 2ouzA-3iu1A:undetectable | 2ouzA-3iu1A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k6g | TELOMERICREPEAT-BINDINGFACTOR 2-INTERACTINGPROTEIN 1TELOMERICREPEAT-BINDINGFACTOR 2 (Homo sapiens;Homo sapiens) |
PF11626(Rap1_C)PF16772(TERF2_RBM) | 5 | LEU A 343LEU A 321MET A 322LEU A 327LEU D 288 | None | 1.07A | 2ouzA-3k6gA:undetectable | 2ouzA-3k6gA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kb1 | NUCLEOTIDE-BINDINGPROTEIN (Archaeoglobusfulgidus) |
PF10609(ParA) | 6 | LEU A 185LEU A 133LEU A 39LEU A 38ILE A 90GLY A 51 | None | 1.38A | 2ouzA-3kb1A:undetectable | 2ouzA-3kb1A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxm | ASPARTATECARBAMOYLTRANSFERASE (Yersinia pestis) |
PF00185(OTCace)PF02729(OTCace_N) | 6 | LEU A 173LEU A 16LEU A 25LEU A 140LEU A 141LEU A 153 | None | 1.32A | 2ouzA-3lxmA:undetectable | 2ouzA-3lxmA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nie | MAP2 KINASE (Plasmodiumfalciparum) |
PF00069(Pkinase) | 5 | LEU A 347LEU A 141ILE A 359HIS A 367LEU A 370 | None | 1.04A | 2ouzA-3nieA:undetectable | 2ouzA-3nieA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oc7 | ENOYL-COA HYDRATASE (Mycobacteriumavium) |
PF00378(ECH_1) | 5 | LEU A 156LEU A 223LEU A 233ILE A 151GLY A 121 | None | 1.03A | 2ouzA-3oc7A:undetectable | 2ouzA-3oc7A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfm | GGDEF DOMAIN PROTEIN (Pseudomonasprotegens) |
PF00563(EAL) | 5 | LEU A 546LEU A 559LEU A 577GLY A 533LEU A 537 | None | 1.01A | 2ouzA-3pfmA:undetectable | 2ouzA-3pfmA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pop | GILR OXIDASE (Streptomycesgriseoflavus) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | LEU A 153LEU A 146LEU A 216LEU A 120GLY A 96 | None | 0.96A | 2ouzA-3popA:undetectable | 2ouzA-3popA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q5w | PROTEIN CUT8 (Schizosaccharomycespombe) |
PF08559(Cut8) | 6 | LEU A 169THR A 170LEU A 177LEU A 126HIS A 197LEU A 194 | None | 1.43A | 2ouzA-3q5wA:undetectable | 2ouzA-3q5wA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7p | RIBOSOMAL PROTEIN3/HOMINGENDONUCLEASE-LIKEFUSION PROTEIN (Leptographiumtruncatum) |
PF00961(LAGLIDADG_1) | 5 | LEU A 34THR A 35LEU A 147LEU A 137GLY A 146 | None | 1.05A | 2ouzA-3r7pA:undetectable | 2ouzA-3r7pA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sdq | ALPHA-BISABOLENESYNTHASE (Abies grandis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | THR A 351LEU A 358LEU A 302LEU A 303GLY A 340 | None | 0.95A | 2ouzA-3sdqA:undetectable | 2ouzA-3sdqA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9w | LEUKOTRIENE A-4HYDROLASE (Homo sapiens) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 5 | LEU A1512LEU A1503LEU A1541LEU A1539ILE A1529 | None | 0.88A | 2ouzA-3u9wA:undetectable | 2ouzA-3u9wA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3um9 | HALOACIDDEHALOGENASE, TYPEII (Polaromonas sp.JS666) |
PF13419(HAD_2) | 5 | LEU A 75LEU A 79GLY A 83HIS A 86LEU A 87 | None | 1.08A | 2ouzA-3um9A:undetectable | 2ouzA-3um9A:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v5n | OXIDOREDUCTASE (Sinorhizobiummeliloti) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | THR A 301LEU A 309LEU A 298LEU A 310ILE A 160 | None | 1.08A | 2ouzA-3v5nA:undetectable | 2ouzA-3v5nA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zwf | ZINCPHOSPHODIESTERASEELAC PROTEIN 1 (Homo sapiens) |
PF00753(Lactamase_B)PF12706(Lactamase_B_2) | 5 | THR A 61LEU A 34LEU A 71GLY A 65HIS A 64 | NoneNoneNoneNone ZN A1364 ( 3.2A) | 1.07A | 2ouzA-3zwfA:undetectable | 2ouzA-3zwfA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axi | ETHANOLAMINECARBOXYSOMESTRUCTURAL PROTEIN (Clostridioidesdifficile) |
PF00936(BMC) | 5 | THR A 111LEU A 102ILE A 24GLY A 47HIS A 23 | None | 0.99A | 2ouzA-4axiA:undetectable | 2ouzA-4axiA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8c | GLUCOSE-REPRESSIBLEALCOHOLDEHYDROGENASETRANSCRIPTIONALEFFECTOR (Saccharomycescerevisiae) |
PF03372(Exo_endo_phos)PF13855(LRR_8) | 5 | LEU D 385LEU D 395LEU D 372GLY D 400LEU D 425 | None | 0.99A | 2ouzA-4b8cD:undetectable | 2ouzA-4b8cD:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btf | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Mus musculus) |
PF07714(Pkinase_Tyr) | 5 | LEU A 61LEU A 38ILE A 8GLY A 11LEU A 68 | None | 1.07A | 2ouzA-4btfA:undetectable | 2ouzA-4btfA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4by6 | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1 (Saccharomycescerevisiae) |
PF04054(Not1) | 5 | LEU A1600LEU A1650LEU A1651ILE A1699LEU A1643 | None | 1.04A | 2ouzA-4by6A:undetectable | 2ouzA-4by6A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ci6 | PROTEIN KINASE YOPO (Yersiniaenterocolitica) |
PF00069(Pkinase)PF09632(Rac1) | 5 | LEU B 252LEU B 251ILE B 385HIS B 402LEU B 405 | None | 0.99A | 2ouzA-4ci6B:undetectable | 2ouzA-4ci6B:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dfc | UVRABC SYSTEMPROTEIN A (Escherichiacoli) |
no annotation | 5 | LEU B 245LEU B 151LEU B 150MET B 149LEU B 148 | None | 0.95A | 2ouzA-4dfcB:undetectable | 2ouzA-4dfcB:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 5 | LEU A 183LEU A 186MET A 187GLY A 284LEU A 281 | None | 1.01A | 2ouzA-4dwsA:undetectable | 2ouzA-4dwsA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e93 | TYROSINE-PROTEINKINASE FES/FPS (Homo sapiens) |
PF00017(SH2)PF07714(Pkinase_Tyr) | 5 | MET A 793LEU A 750LEU A 756LEU A 660ILE A 817 | None | 0.90A | 2ouzA-4e93A:undetectable | 2ouzA-4e93A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fye | SIDF, INHIBITOR OFGROWTH FAMILY,MEMBER 3 (Legionellapneumophila) |
no annotation | 5 | MET A 382LEU A 294THR A 293LEU A 238LEU A 287 | None | 1.02A | 2ouzA-4fyeA:undetectable | 2ouzA-4fyeA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hes | BETA-LACTAMASE CLASSA-LIKE PROTEIN (Veillonellaparvula) |
PF13354(Beta-lactamase2) | 5 | LEU A 171LEU A 243MET A 244GLY A 256LEU A 204 | None | 0.99A | 2ouzA-4hesA:undetectable | 2ouzA-4hesA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i5v | 5',5'''-P-1,P-4-TETRAPHOSPHATEPHOSPHORYLASE 2 (Saccharomycescerevisiae) |
PF09830(ATP_transf) | 6 | LEU A 127THR A 254LEU A 220LEU A 120MET A 121LEU A 208 | None | 1.43A | 2ouzA-4i5vA:undetectable | 2ouzA-4i5vA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6k | AMIDOHYDROLASEFAMILY PROTEIN (Acinetobacterbaumannii) |
PF04909(Amidohydro_2) | 5 | LEU A 109LEU A 140LEU A 143GLY A 160HIS A 158 | NoneNoneNoneNoneCIT A 301 (-4.1A) | 0.89A | 2ouzA-4i6kA:undetectable | 2ouzA-4i6kA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i8o | TOXIN RNLA (Escherichiacoli) |
PF15935(RnlA_toxin) | 5 | LEU A 255LEU A 179LEU A 188GLY A 234LEU A 230 | None | 1.03A | 2ouzA-4i8oA:undetectable | 2ouzA-4i8oA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ixo | NIFS-LIKE PROTEIN (Rickettsiaafricae) |
PF00266(Aminotran_5) | 5 | LEU A 290THR A 289LEU A 4ILE A 293LEU A 269 | None | 1.00A | 2ouzA-4ixoA:undetectable | 2ouzA-4ixoA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ksf | MALONYL-COADECARBOXYLASE (Agrobacteriumvitis) |
PF05292(MCD)PF17408(MCD_N) | 5 | LEU A 44LEU A 134LEU A 121GLY A 130LEU A 61 | None | 0.94A | 2ouzA-4ksfA:undetectable | 2ouzA-4ksfA:20.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 5 | LEU A 283LEU A 291LEU A 324ILE A 361GLY A 447 | None | 0.68A | 2ouzA-4n1yA:26.3 | 2ouzA-4n1yA:38.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1i | TRANSCRIPTIONALREGULATORY PROTEIN (Mycobacteriumtuberculosis) |
no annotation | 5 | LEU A 64LEU A 47ILE A 104HIS A 25LEU A 4 | None | 0.94A | 2ouzA-4o1iA:undetectable | 2ouzA-4o1iA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1o | RIBONUCLEASE L (Sus scrofa) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A)PF12796(Ank_2)PF13857(Ank_5) | 5 | LEU A 715LEU A 593ILE A 602GLY A 668LEU A 667 | None | 1.07A | 2ouzA-4o1oA:undetectable | 2ouzA-4o1oA:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4per | RIBONUCLEASEINHIBITOR (Gallus gallus) |
PF13516(LRR_6) | 5 | LEU A 142LEU A 161LEU A 167GLY A 188LEU A 185 | None | 0.97A | 2ouzA-4perA:undetectable | 2ouzA-4perA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2b | ENDO-1,4-BETA-D-GLUCANASE (Pseudomonasputida) |
PF01270(Glyco_hydro_8) | 5 | LEU A 163LEU A 222LEU A 208GLY A 160LEU A 156 | None | 1.04A | 2ouzA-4q2bA:undetectable | 2ouzA-4q2bA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbj | GLYCYLPEPTIDEN-TETRADECANOYLTRANSFERASE (Aspergillusfumigatus) |
PF01233(NMT)PF02799(NMT_C) | 5 | LEU A 143LEU A 128LEU A 168GLY A 180LEU A 189 | None | 1.03A | 2ouzA-4qbjA:undetectable | 2ouzA-4qbjA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rz2 | SITE-DETERMININGPROTEIN (Geobacillusthermodenitrificans) |
PF10609(ParA) | 5 | LEU A 55LEU A 88LEU A 126LEU A 123LEU A 78 | None | 0.92A | 2ouzA-4rz2A:undetectable | 2ouzA-4rz2A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tu3 | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 74 (Saccharomycescerevisiae) |
PF05719(GPP34) | 5 | LEU A 69THR A 68LEU A 96ILE A 101LEU A 141 | None | 1.04A | 2ouzA-4tu3A:undetectable | 2ouzA-4tu3A:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx2 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Actinoplanesteichomyceticus) |
PF00668(Condensation) | 5 | MET B 259LEU B 262LEU B 270HIS B 245LEU B 240 | None | 0.96A | 2ouzA-4tx2B:undetectable | 2ouzA-4tx2B:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uaq | PROTEIN TRANSLOCASESUBUNIT SECA 2 (Mycobacteriumtuberculosis) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 5 | LEU A 102LEU A 99LEU A 95GLY A 125LEU A 62 | None | 0.85A | 2ouzA-4uaqA:undetectable | 2ouzA-4uaqA:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4us5 | LUCIFERASE-LIKEMONOOXYGENASE (Streptomycesbottropensis) |
PF00296(Bac_luciferase) | 5 | LEU A 78LEU A 167LEU A 166LEU A 164GLY A 74 | None | 0.96A | 2ouzA-4us5A:undetectable | 2ouzA-4us5A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uw2 | CSM1 (Thermococcusonnurineus) |
PF01966(HD) | 6 | LEU A 9LEU A 38LEU A 53LEU A 55GLY A 34HIS A 30 | None | 1.50A | 2ouzA-4uw2A:undetectable | 2ouzA-4uw2A:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xri | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | LEU A 592THR A 588LEU A 631MET A 635GLY A 600 | None | 1.04A | 2ouzA-4xriA:undetectable | 2ouzA-4xriA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0a | SHIKIMATE KINASE (Acinetobacterbaumannii) |
PF01202(SKI) | 5 | LEU A 23THR A 94LEU A 90ILE A 113GLY A 112 | None | 0.97A | 2ouzA-4y0aA:undetectable | 2ouzA-4y0aA:25.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylq | COAGULATION FACTORVII (Homo sapiens) |
PF00089(Trypsin) | 5 | LEU H 46THR H 45LEU H 105LEU H 106LEU H 108 | None | 0.98A | 2ouzA-4ylqH:undetectable | 2ouzA-4ylqH:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a30 | MITOCHONDRIALPROTEIN (Gallus gallus) |
PF03828(PAP_assoc) | 5 | LEU A 334LEU A 396LEU A 393LEU A 454ILE A 390 | None | 1.05A | 2ouzA-5a30A:undetectable | 2ouzA-5a30A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5amq | RNA POLYMERASE L (Californiaencephalitisorthobunyavirus) |
PF04196(Bunya_RdRp)PF15518(L_protein_N) | 6 | MET A1302LEU A1305THR A1306LEU A1512LEU A 519MET A 515 | NoneNoneNone C B 10 ( 4.2A)NoneNone | 1.42A | 2ouzA-5amqA:undetectable | 2ouzA-5amqA:7.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bz4 | BETA-KETOTHIOLASE (Mycolicibacteriumsmegmatis) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 31LEU A 39GLY A 56HIS A 57LEU A 55 | None | 0.95A | 2ouzA-5bz4A:undetectable | 2ouzA-5bz4A:22.03 |