SIMILAR PATTERNS OF AMINO ACIDS FOR 2OTV_A_NCAA1301

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a0j TRYPSIN

(Salmo salar) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 BEN  A 246 (-3.0A)
BEN  A 246 (-3.0A)
SO4  A 248 ( 2.5A)
None
BEN  A 246 ( 3.9A)
BEN  A 246 (-3.3A)
 0.15A 2otvA-1a0jA:
41.6		 2otvA-1a0jA:
73.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a5i PLASMINOGEN
ACTIVATOR

(Desmodus
rotundus) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 0GJ  A 245 (-3.1A)
0GJ  A 245 (-1.4A)
0GJ  A 245 (-3.5A)
0GJ  A 245 ( 4.2A)
 0.32A 2otvA-1a5iA:
11.7		 2otvA-1a5iA:
37.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1afq BOVINE
GAMMA-CHYMOTRYPSIN

(Bos taurus) 		PF00089
(Trypsin) 		5 SER C 190
SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.51A 2otvA-1afqC:
11.5		 2otvA-1afqC:
22.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
 0GJ  A   1 (-3.1A)
0GJ  A   1 ( 1.4A)
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
 0.29A 2otvA-1bqyA:
35.8		 2otvA-1bqyA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bru ELASTASE

(Sus scrofa) 		PF00089
(Trypsin) 		4 SER P 190
SER P 195
VAL P 213
GLY P 216
 1NB  P   1 (-3.5A)
1NB  P   1 ( 1.2A)
None
1NB  P   1 ( 4.4A)
 0.45A 2otvA-1bruP:
16.7		 2otvA-1bruP:
40.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cte CATHEPSIN B

(Rattus
norvegicus) 		PF00112
(Peptidase_C1) 		5 SER A  90
SER A  39
VAL A  52
GLY A  92
GLY A  99
 None
 1.13A 2otvA-1cteA:
undetectable		 2otvA-1cteA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dlk THROMBIN HEAVY CHAIN

(Bos taurus) 		PF00089
(Trypsin) 		5 SER B 190
SER B 195
VAL B 213
GLY B 216
GLY B 226
 None
 0.50A 2otvA-1dlkB:
36.7		 2otvA-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ekb ENTEROPEPTIDASE

(Bos taurus) 		PF00089
(Trypsin) 		5 ASP B 189
SER B 190
SER B 195
GLY B 216
GLY B 226
 None
 0.27A 2otvA-1ekbB:
36.6		 2otvA-1ekbB:
36.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1elv COMPLEMENT C1S
COMPONENT

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		6 ASP A 611
SER A 612
SER A 617
VAL A 638
GLY A 641
GLY A 648
 None
None
SO4  A2001 ( 2.7A)
None
None
None
 0.23A 2otvA-1elvA:
11.0		 2otvA-1elvA:
30.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ept PORCINE E-TRYPSIN

(Sus scrofa) 		PF00089
(Trypsin) 		6 ASP C 189
SER C 190
SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
 0.24A 2otvA-1eptC:
16.2		 2otvA-1eptC:
81.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1euf DUODENASE

(Bos taurus) 		PF00089
(Trypsin) 		4 SER A 190
SER A 195
VAL A 213
GLY A 216
 None
 0.27A 2otvA-1eufA:
36.0		 2otvA-1eufA:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fi8 NATURAL KILLER CELL
PROTEASE 1

(Rattus
norvegicus) 		PF00089
(Trypsin) 		4 SER A 190
SER A 195
VAL A 213
GLY A 216
 None
 0.39A 2otvA-1fi8A:
36.1		 2otvA-1fi8A:
38.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fiw BETA-ACROSIN HEAVY
CHAIN

(Ovis aries) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 PBZ  A 305 (-2.7A)
PBZ  A 305 (-2.9A)
PBZ  A 305 (-3.4A)
PBZ  A 305 (-3.3A)
 0.23A 2otvA-1fiwA:
16.4		 2otvA-1fiwA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fiz BETA-ACROSIN HEAVY
CHAIN

(Sus scrofa) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 PBZ  A 308 (-2.9A)
PBZ  A 308 (-3.2A)
PBZ  A 308 (-3.6A)
PBZ  A 308 ( 3.7A)
 0.36A 2otvA-1fizA:
17.1		 2otvA-1fizA:
37.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fq3 GRANZYME B

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 190
SER A 195
VAL A 213
GLY A 216
 None
SO4  A 800 (-2.4A)
None
None
 0.68A 2otvA-1fq3A:
11.6		 2otvA-1fq3A:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fxy COAGULATION FACTOR
XA-TRYPSIN CHIMERA

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 0G6  A   1 (-2.8A)
0G6  A   1 (-2.8A)
0G6  A   1 (-1.4A)
None
0G6  A   1 (-3.9A)
0G6  A   1 (-3.3A)
 0.25A 2otvA-1fxyA:
38.2		 2otvA-1fxyA:
55.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gk2 HISTIDINE
AMMONIA-LYASE

(Pseudomonas
putida) 		PF00221
(Lyase_aromatic) 		5 ASP A 145
SER A 200
VAL A 334
GLY A 329
GLY A 141
 None
 1.08A 2otvA-1gk2A:
undetectable		 2otvA-1gk2A:
17.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gvl KALLIKREIN 6

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.69A 2otvA-1gvlA:
28.3		 2otvA-1gvlA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1h4w TRYPSIN IVA

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 BEN  A 250 (-2.9A)
BEN  A 250 (-2.9A)
BEN  A 250 (-3.6A)
None
BEN  A 250 (-3.9A)
BEN  A 250 (-3.3A)
 0.18A 2otvA-1h4wA:
43.4		 2otvA-1h4wA:
72.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1h9h TRYPSIN

(Sus scrofa) 		PF00089
(Trypsin) 		6 ASP E 189
SER E 190
SER E 195
VAL E 213
GLY E 216
GLY E 226
 None
 0.25A 2otvA-1h9hE:
43.0		 2otvA-1h9hE:
82.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1id5 THROMBIN

(Bos taurus) 		PF00089
(Trypsin) 		5 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.41A 2otvA-1id5H:
34.4		 2otvA-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1j17 TRYPSIN II, ANIONIC

(Rattus
norvegicus) 		PF00089
(Trypsin) 		5 ASP T 189
SER T 195
VAL T 213
GLY T 216
GLY T 226
 ZEN  T   1 ( 3.8A)
SO4  T 600 ( 2.6A)
ZEN  T   1 (-4.1A)
ZEN  T   1 (-3.7A)
ZEN  T   1 (-3.7A)
 0.13A 2otvA-1j17T:
43.0		 2otvA-1j17T:
71.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kig FACTOR XA

(Bos taurus) 		PF00089
(Trypsin) 		5 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.36A 2otvA-1kigH:
34.5		 2otvA-1kigH:
40.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mbq TRYPSIN

(Oncorhynchus
keta) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 BEN  A1222 (-2.9A)
BEN  A1222 (-2.9A)
BEN  A1222 (-3.5A)
None
BEN  A1222 (-3.9A)
BEN  A1222 (-3.4A)
 0.23A 2otvA-1mbqA:
41.1		 2otvA-1mbqA:
65.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1npm NEUROPSIN

(Mus musculus) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.27A 2otvA-1npmA:
37.8		 2otvA-1npmA:
45.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1o5f SERINE PROTEASE
HEPSIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 CR9  H 256 (-2.4A)
CR9  H 256 (-1.5A)
CR9  H 256 (-4.3A)
CR9  H 256 ( 3.8A)
CR9  H 256 (-3.0A)
 0.18A 2otvA-1o5fH:
19.2		 2otvA-1o5fH:
41.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1op2 VENOM SERINE
PROTEINASE

(Deinagkistrodon
acutus) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.33A 2otvA-1op2A:
34.8		 2otvA-1op2A:
41.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1orf GRANZYME A

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 190
SER A 195
GLY A 216
GLY A 226
 0G6  A   1 (-2.9A)
0G6  A   1 (-2.9A)
0G6  A   1 (-1.3A)
0G6  A   1 (-3.3A)
0G6  A   1 (-3.5A)
 0.22A 2otvA-1orfA:
12.8		 2otvA-1orfA:
35.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pfx FACTOR IXA

(Sus scrofa) 		PF00089
(Trypsin) 		5 ASP C 189
SER C 190
SER C 195
GLY C 216
GLY C 226
 0G6  C 301 (-3.0A)
0G6  C 301 (-2.6A)
0G6  C 301 (-1.4A)
0G6  C 301 (-3.2A)
0G6  C 301 ( 3.5A)
 0.38A 2otvA-1pfxC:
34.9		 2otvA-1pfxC:
43.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pq5 TRYPSIN

(Fusarium
oxysporum) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 210
GLY A 213
GLY A 223
 ARG  A 703 (-2.0A)
ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.25A 2otvA-1pq5A:
34.0		 2otvA-1pq5A:
44.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q3x MANNAN-BINDING
LECTIN SERINE
PROTEASE 2

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		6 ASP A 627
SER A 628
SER A 633
VAL A 653
GLY A 656
GLY A 667
 NA  A 800 ( 4.6A)
GOL  A 701 (-3.4A)
GOL  A 701 (-3.0A)
GOL  A 701 (-4.9A)
GOL  A 701 ( 4.1A)
GOL  A 701 ( 4.0A)
 0.39A 2otvA-1q3xA:
34.1		 2otvA-1q3xA:
29.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sgf NERVE GROWTH FACTOR

(Mus musculus) 		PF00089
(Trypsin) 		4 ASP G 189
SER G 195
GLY G 216
GLY G 226
 None
 0.33A 2otvA-1sgfG:
36.8		 2otvA-1sgfG:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ym0 FIBRINOTIC ENZYME
COMPONENT B

(Eisenia fetida) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.24A 2otvA-1ym0A:
36.2		 2otvA-1ym0A:
39.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zca G ALPHA I/12

(Mus musculus) 		PF00503
(G-alpha) 		4 SER A  66
SER A  69
GLY A 228
GLY A  62
 GDP  A 382 (-2.9A)
MG  A 383 ( 2.1A)
ALF  A 384 (-3.3A)
None
 0.73A 2otvA-1zcaA:
undetectable		 2otvA-1zcaA:
18.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zlr COAGULATION FACTOR
XI

(Homo sapiens) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 368  A 901 (-2.8A)
368  A 901 (-1.4A)
368  A 901 (-3.6A)
368  A 901 (-3.5A)
 0.28A 2otvA-1zlrA:
33.9		 2otvA-1zlrA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2aip PROTEIN C ACTIVATOR

(Agkistrodon
contortrix) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
SO4  A 301 (-2.8A)
None
None
 0.49A 2otvA-2aipA:
34.0		 2otvA-2aipA:
39.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5n DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF10433
(MMS1_N) 		4 ASP A 654
SER A 653
GLY A 609
GLY A 632
 None
 0.78A 2otvA-2b5nA:
undetectable		 2otvA-2b5nA:
21.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2eek TRYPSIN-1

(Gadus morhua) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 BEN  A 301 (-2.7A)
BEN  A 301 (-2.8A)
BEN  A 301 (-3.4A)
None
BEN  A 301 ( 3.8A)
BEN  A 301 (-3.2A)
 0.21A 2otvA-2eekA:
40.2		 2otvA-2eekA:
62.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ei8 COAGULATION FACTOR
X, HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
 DT8  A 700 (-3.5A)
DT8  A 700 ( 3.9A)
DT8  A 700 ( 4.1A)
DT8  A 700 (-3.5A)
DT8  A 700 (-3.5A)
 0.28A 2otvA-2ei8A:
35.8		 2otvA-2ei8A:
38.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f91 HEPATOPANCREAS
TRYPSIN

(Astacus
leptodactylus) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 227
 None
 0.26A 2otvA-2f91A:
36.8		 2otvA-2f91A:
44.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iou MAJOR TROPISM
DETERMINANT P1

(Bordetella
virus BPP1) 		no annotation 4 SER A 271
VAL A 276
GLY A 285
GLY A 273
 None
 0.76A 2otvA-2iouA:
undetectable		 2otvA-2iouA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipp CATHEPSIN B
CATHEPSIN B

(Homo sapiens;
Homo sapiens) 		PF00112
(Peptidase_C1)
PF00112
(Peptidase_C1) 		5 ASP B 143
SER A  39
VAL B  52
GLY B  91
GLY B  99
 None
 1.39A 2otvA-2ippB:
undetectable		 2otvA-2ippB:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jet CHYMOTRYPSINOGEN B
CHAIN C

(Rattus
norvegicus) 		PF00089
(Trypsin) 		4 SER C 195
VAL C 213
GLY C 216
GLY C 226
 None
 0.65A 2otvA-2jetC:
9.6		 2otvA-2jetC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mna SINGLE-STRANDED DNA
BINDING PROTEIN
(SSB)

(Sulfolobus
solfataricus) 		PF01336
(tRNA_anti-codon) 		4 ASP A  46
VAL A  51
GLY A   6
GLY A  49
 None
 0.78A 2otvA-2mnaA:
undetectable		 2otvA-2mnaA:
17.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oq5 TRANSMEMBRANE
PROTEASE, SERINE 11E

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
 BEN  A 245 (-3.0A)
BEN  A 245 (-3.3A)
None
BEN  A 245 ( 3.8A)
BEN  A 245 (-3.4A)
 0.19A 2otvA-2oq5A:
14.5		 2otvA-2oq5A:
37.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owm RELATED TO
KINESIN-LIKE PROTEIN
KIF1C

(Neurospora
crassa) 		PF00225
(Kinesin) 		4 SER A 148
SER A 151
GLY A 302
GLY A 144
 ADP  A1002 (-3.4A)
MG  A1001 ( 1.9A)
None
None
 0.76A 2otvA-2owmA:
undetectable		 2otvA-2owmA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pks THROMBIN HEAVY CHAIN
FRAGMENT

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP C 229
SER C 235
VAL C 255
GLY C 258
GLY C 268
 G44  C 101 (-2.6A)
G44  C 101 (-3.5A)
None
G44  C 101 (-3.3A)
G44  C 101 (-3.0A)
 0.24A 2otvA-2pksC:
12.4		 2otvA-2pksC:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2psy KALLIKREIN-5

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.26A 2otvA-2psyA:
38.8		 2otvA-2psyA:
47.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3f RAS-RELATED
GTP-BINDING PROTEIN
D

(Homo sapiens) 		PF04670
(Gtr1_RagA) 		4 SER A  54
SER A  57
GLY A 101
GLY A  50
 GNP  A 401 (-3.5A)
MG  A 301 ( 2.1A)
GNP  A 401 (-3.2A)
None
 0.76A 2otvA-2q3fA:
undetectable		 2otvA-2q3fA:
21.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qy0 COMPLEMENT C1R
SUBCOMPONENT

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP B 631
SER B 637
VAL B 657
GLY B 660
GLY B 668
 None
 0.43A 2otvA-2qy0B:
32.1		 2otvA-2qy0B:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r0l HEPATOCYTE GROWTH
FACTOR ACTIVATOR

(Homo sapiens) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.34A 2otvA-2r0lA:
18.5		 2otvA-2r0lA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r2w PLASMINOGEN
ACTIVATOR, UROKINASE

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP U 189
SER U 190
VAL U 213
GLY U 216
GLY U 226
 4PG  U 300 (-2.8A)
4PG  U 300 (-2.7A)
None
4PG  U 300 (-3.3A)
4PG  U 300 (-3.2A)
 0.42A 2otvA-2r2wU:
15.5		 2otvA-2r2wU:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wpm COAGULATION FACTOR
IXA HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP S 189
SER S 190
SER S 195
GLY S 216
GLY S 226
 None
 0.19A 2otvA-2wpmS:
36.2		 2otvA-2wpmS:
41.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT

(Arabidopsis
thaliana) 		PF00503
(G-alpha) 		4 SER A  49
SER A  52
GLY A 221
GLY A  45
 GSP  A1382 (-3.4A)
MG  A1381 ( 2.0A)
GSP  A1382 (-3.4A)
None
 0.73A 2otvA-2xtzA:
undetectable		 2otvA-2xtzA:
20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zec TRYPTASE BETA 2

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP A 203
SER A 204
SER A 209
VAL A 227
GLY A 230
GLY A 240
 11N  A   1 (-2.6A)
11N  A   1 (-3.5A)
11N  A   1 (-3.3A)
None
11N  A   1 (-3.9A)
11N  A   1 (-3.6A)
 0.36A 2otvA-2zecA:
32.9		 2otvA-2zecA:
40.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 SER A 634
VAL A 601
GLY A 704
GLY A 708
 None
 0.72A 2otvA-3aqpA:
undetectable		 2otvA-3aqpA:
14.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3beu TRYPSIN

(Streptomyces
griseus) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
 BEN  A 247 (-3.0A)
SO4  A 246 ( 2.5A)
None
BEN  A 247 (-3.7A)
BEN  A 247 (-3.5A)
 0.16A 2otvA-3beuA:
32.3		 2otvA-3beuA:
36.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bu1 LIPOCALIN

(Argas
monolakensis) 		PF02098
(His_binding) 		5 ASP A  94
SER A  88
SER A   8
VAL A   7
GLY A  15
 HSM  A 301 (-2.9A)
None
None
None
None
 1.43A 2otvA-3bu1A:
undetectable		 2otvA-3bu1A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cx6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-13
SUBUNIT

(Mus musculus) 		PF00503
(G-alpha) 		4 SER A  59
SER A  62
GLY A 225
GLY A  55
 GDP  A 775 (-3.4A)
MG  A 675 ( 2.7A)
None
None
 0.74A 2otvA-3cx6A:
undetectable		 2otvA-3cx6A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cx6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-13
SUBUNIT

(Mus musculus) 		PF00503
(G-alpha) 		5 SER A 268
SER A 248
VAL A 247
GLY A  57
GLY A  55
 None
None
None
GDP  A 775 ( 4.2A)
None
 1.18A 2otvA-3cx6A:
undetectable		 2otvA-3cx6A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmy PROTEIN FDRA

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		5 ASP A 230
SER A 239
VAL A 170
GLY A 225
GLY A 227
 None
 1.49A 2otvA-3dmyA:
undetectable		 2otvA-3dmyA:
17.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3f6u VITAMIN K-DEPENDENT
PROTEIN C HEAVY
CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 0G6  H   1 (-2.8A)
0G6  H   1 (-1.8A)
None
0G6  H   1 (-3.8A)
0G6  H   1 ( 3.9A)
 0.30A 2otvA-3f6uH:
35.4		 2otvA-3f6uH:
36.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gaf 7-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE

(Brucella
abortus) 		PF13561
(adh_short_C2) 		4 SER A 145
VAL A 166
GLY A 160
GLY A 149
 None
 0.74A 2otvA-3gafA:
undetectable		 2otvA-3gafA:
21.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gov MASP-1

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP B 640
SER B 646
VAL B 666
GLY B 669
GLY B 679
 None
 0.43A 2otvA-3govB:
35.5		 2otvA-3govB:
35.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gym PROSTASIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.25A 2otvA-3gymA:
34.9		 2otvA-3gymA:
40.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE

(Bacteroides
ovatus) 		no annotation 4 SER A 290
SER A 224
GLY A 239
GLY A 270
 None
 0.78A 2otvA-3n6zA:
undetectable		 2otvA-3n6zA:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r3g THROMBIN HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP B 189
SER B 195
VAL B 213
GLY B 216
GLY B 226
 None
 0.33A 2otvA-3r3gB:
34.2		 2otvA-3r3gB:
37.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7w GTP-BINDING PROTEIN
GTR1

(Saccharomyces
cerevisiae) 		PF04670
(Gtr1_RagA) 		4 SER A  17
SER A  20
GLY A  64
GLY A  13
 GNP  A 500 (-3.6A)
MG  A 600 ( 2.0A)
GNP  A 500 (-3.8A)
None
 0.79A 2otvA-3r7wA:
undetectable		 2otvA-3r7wA:
18.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3s69 THROMBIN-LIKE ENZYME
DEFIBRASE

(Gloydius
saxatilis) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 195
VAL A 209
GLY A 212
GLY A 223
 None
 0.43A 2otvA-3s69A:
35.2		 2otvA-3s69A:
44.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3s9b VIPERA RUSSELLI
PROTEINASE RVV-V
GAMMA

(Daboia
siamensis) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
VAL A 213
GLY A 216
 None
 0.53A 2otvA-3s9bA:
13.1		 2otvA-3s9bA:
41.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w94 ENTEROPEPTIDASE-1

(Oryzias latipes) 		PF00089
(Trypsin) 		5 ASP A 973
SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.22A 2otvA-3w94A:
37.0		 2otvA-3w94A:
35.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zjc GTPASE IMAP FAMILY
MEMBER 7

(Homo sapiens) 		PF04548
(AIG1) 		4 SER A  19
SER A  22
GLY A  66
GLY A  15
 GNP  A1297 (-3.9A)
MG  A1296 ( 2.4A)
GNP  A1297 ( 4.3A)
None
 0.71A 2otvA-3zjcA:
undetectable		 2otvA-3zjcA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxw FACTOR XA

(Pseudonaja
textilis) 		PF00089
(Trypsin)
PF14670
(FXa_inhibition) 		5 ASP A 356
SER A 362
VAL A 380
GLY A 383
GLY A 393
 0GJ  A1411 (-2.7A)
0GJ  A1411 (-1.4A)
None
0GJ  A1411 (-3.7A)
0GJ  A1411 (-3.3A)
 0.21A 2otvA-4bxwA:
33.0		 2otvA-4bxwA:
23.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4d9r COMPLEMENT FACTOR D

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 226
 None
 0.53A 2otvA-4d9rA:
16.5		 2otvA-4d9rA:
37.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dgj ENTEROPEPTIDASE
CATALYTIC LIGHT
CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 ASP A 181
SER A 182
GLY A 208
GLY A 218
 None
 0.16A 2otvA-4dgjA:
37.0		 2otvA-4dgjA:
37.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fxg MANNAN-BINDING
LECTIN SERINE
PROTEASE 2 B CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP H 627
SER H 628
VAL H 653
GLY H 656
GLY H 667
 None
 0.33A 2otvA-4fxgH:
33.5		 2otvA-4fxgH:
36.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gso THROMBIN-LIKE ENZYME
BJUSSUSP-1

(Bothrops
jararacussu) 		PF00089
(Trypsin) 		5 ASP A 172
SER A 178
VAL A 192
GLY A 195
GLY A 206
 None
 0.46A 2otvA-4gsoA:
undetectable		 2otvA-4gsoA:
44.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iu9 NITRITE EXTRUSION
PROTEIN 2

(Escherichia
coli) 		no annotation 4 SER B 272
VAL B 176
GLY B 299
GLY B 295
 None
 0.76A 2otvA-4iu9B:
undetectable		 2otvA-4iu9B:
17.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4iw4 MANNAN-BINDING
LECTIN SERINE
PROTEASE 3

(Homo sapiens) 		PF00089
(Trypsin) 		5 ASP E 639
SER E 645
VAL E 665
GLY E 668
GLY E 680
 None
 0.50A 2otvA-4iw4E:
33.7		 2otvA-4iw4E:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k8y KALLIKREIN-4

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.39A 2otvA-4k8yA:
37.0		 2otvA-4k8yA:
40.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspora
erythraea) 		PF00089
(Trypsin) 		4 ASP A 173
SER A 179
GLY A 196
GLY A 206
 None
 0.31A 2otvA-4m7gA:
33.8		 2otvA-4m7gA:
40.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4y COXSACKIEVIRUS
CAPSID PROTEIN VP1
COXSACKIEVIRUS
CAPSID PROTEIN VP2

(Enterovirus C;
Enterovirus C) 		PF00073
(Rhv)
PF00073
(Rhv) 		5 ASP 1 287
SER 2 141
VAL 1 234
GLY 1 283
GLY 1 285
 None
None
HEZ  15003 ( 4.7A)
None
None
 1.20A 2otvA-4q4y1:
undetectable		 2otvA-4q4y1:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qed ELXO

(Staphylococcus
epidermidis) 		PF13561
(adh_short_C2) 		4 SER A 139
VAL A 160
GLY A 154
GLY A 143
 None
 0.78A 2otvA-4qedA:
undetectable		 2otvA-4qedA:
21.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r0i SUPPRESSOR OF
TUMORIGENICITY 14
PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 3KM  A 900 (-2.9A)
3KM  A 900 (-2.9A)
3KM  A 900 (-3.6A)
None
3KM  A 900 (-3.4A)
3KM  A 900 (-3.2A)
 0.15A 2otvA-4r0iA:
37.6		 2otvA-4r0iA:
40.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wwy TRYPSIN-1

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP A 189
SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.22A 2otvA-4wwyA:
42.0		 2otvA-4wwyA:
74.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ylq COAGULATION FACTOR
VII

(Homo sapiens) 		PF00089
(Trypsin) 		6 ASP H 189
SER H 190
SER H 195
VAL H 213
GLY H 216
GLY H 226
 0Z7  H 501 (-2.3A)
0Z7  H 501 (-2.3A)
0Z7  H 501 (-1.4A)
0Z7  H 501 ( 4.7A)
0Z7  H 501 (-3.4A)
0Z7  H 501 (-3.0A)
 0.21A 2otvA-4ylqH:
35.6		 2otvA-4ylqH:
40.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f8z PLASMA KALLIKREIN
LIGHT CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.53A 2otvA-5f8zA:
34.5		 2otvA-5f8zA:
41.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gkx UNCHARACTERIZED
PROTEIN

(Thermococcus
onnurineus) 		PF14336
(DUF4392) 		5 ASP A  61
SER A 196
VAL A 155
GLY A  65
GLY A  62
 None
 1.37A 2otvA-5gkxA:
undetectable		 2otvA-5gkxA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvt PLASMA KALLIKREIN

(Mus musculus) 		no annotation 4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.49A 2otvA-5gvtA:
33.4		 2otvA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcx (-)-ISOPIPERITENONE
REDUCTASE

(Mentha x
piperita) 		PF00106
(adh_short) 		4 SER A 241
VAL A 151
GLY A  98
GLY A 146
 None
 0.73A 2otvA-5lcxA:
undetectable		 2otvA-5lcxA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg3 PROTEIN TRANSLOCASE
SUBUNIT SECF

(Escherichia
coli) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 ASP F 213
SER F 214
VAL F 173
GLY F 284
 None
 0.60A 2otvA-5mg3F:
undetectable		 2otvA-5mg3F:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ms3 KALLIKREIN-8

(Homo sapiens) 		no annotation 4 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.24A 2otvA-5ms3A:
38.3		 2otvA-5ms3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyn DEHYDRATASE,
ILVD/EDD FAMILY

(Caulobacter
vibrioides) 		no annotation 4 ASP A 486
SER A 505
GLY A 457
GLY A 452
 None
 0.77A 2otvA-5oynA:
undetectable		 2otvA-5oynA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5to3 PROTHROMBIN,THROMBOM
ODULIN

(Homo sapiens) 		PF00089
(Trypsin)
PF09064
(Tme5_EGF_like) 		5 ASP B 214
SER B 220
VAL B 240
GLY B 243
GLY B 253
 0G6  B 501 (-2.9A)
0G6  B 501 (-1.3A)
None
0G6  B 501 (-3.7A)
0G6  B 501 (-3.6A)
 0.20A 2otvA-5to3B:
34.8		 2otvA-5to3B:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubk ACYL-HOMOSERINE
LACTONE ACYLASE PVDQ

(Pseudomonas
aeruginosa) 		PF01804
(Penicil_amidase) 		4 SER A 327
VAL A 325
GLY A 456
GLY A 454
 None
None
83M  A 801 (-4.8A)
None
 0.76A 2otvA-5ubkA:
undetectable		 2otvA-5ubkA:
16.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ubm COMPLEMENT C1S
SUBCOMPONENT

(Homo sapiens) 		no annotation 6 ASP A 626
SER A 627
SER A 632
VAL A 653
GLY A 656
GLY A 663
 None
 0.46A 2otvA-5ubmA:
11.7		 2otvA-5ubmA:
34.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xrf SNAKE VENOM SERINE
PROTEASE DA-36

(Deinagkistrodon
acutus) 		no annotation 5 ASP A 200
SER A 206
VAL A 220
GLY A 223
GLY A 234
 None
 0.63A 2otvA-5xrfA:
13.5		 2otvA-5xrfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zfh KALLIKREIN-7

(Mus musculus) 		no annotation 4 SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.37A 2otvA-5zfhA:
37.8		 2otvA-5zfhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT

(Homo sapiens) 		no annotation 4 SER A  51
SER A  54
GLY A 226
GLY A  47
 GDP  A 401 (-3.4A)
MG  A 402 ( 2.1A)
None
None
 0.71A 2otvA-6au6A:
undetectable		 2otvA-6au6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b74 COAGULATION FACTOR
XII

(Homo sapiens) 		no annotation 4 ASP B 189
SER B 195
GLY B 216
GLY B 226
 BEN  B 301 (-2.7A)
SO4  B 304 ( 2.5A)
BEN  B 301 (-3.3A)
BEN  B 301 (-3.1A)
 0.22A 2otvA-6b74B:
13.7		 2otvA-6b74B:
undetectable