SIMILAR PATTERNS OF AMINO ACIDS FOR 2OTF_A_2TNA201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a2a PHOSPHOLIPASE A2

(Gloydius halys) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
ILE A  19
GLY A  30
HIS A  48
 None
 0.80A 2otfA-1a2aA:
22.3		 2otfA-1a2aA:
62.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ac5 KEX1(DELTA)P

(Saccharomyces
cerevisiae) 		PF00450
(Peptidase_S10) 		4 ILE A 108
SER A 106
GLY A 105
HIS A 417
 None
 0.83A 2otfA-1ac5A:
undetectable		 2otfA-1ac5A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1am5 PEPSIN

(Gadus morhua) 		PF00026
(Asp) 		4 LEU A  73
ILE A 128
SER A  36
GLY A 122
 None
 1.00A 2otfA-1am5A:
undetectable		 2otfA-1am5A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bjn PHOSPHOSERINE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00266
(Aminotran_5) 		4 LEU A  60
ILE A 200
SER A 249
GLY A 250
 None
 1.01A 2otfA-1bjnA:
undetectable		 2otfA-1bjnA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d1t ALCOHOL
DEHYDROGENASE CLASS
IV SIGMA CHAIN

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 345
ILE A 172
SER A 177
GLY A 179
 None
 0.96A 2otfA-1d1tA:
undetectable		 2otfA-1d1tA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ept PORCINE E-TRYPSIN

(Sus scrofa) 		PF00089
(Trypsin) 		4 LEU C 155
ILE B  73
SER A  32
GLY A  43
 None
 0.92A 2otfA-1eptC:
undetectable		 2otfA-1eptC:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4w TRYPSIN IVA

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU A 155
ILE A  73
SER A  32
GLY A  43
 None
 0.97A 2otfA-1h4wA:
undetectable		 2otfA-1h4wA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h9h TRYPSIN

(Sus scrofa) 		PF00089
(Trypsin) 		4 LEU E 155
ILE E  73
SER E  32
GLY E  43
 None
 0.94A 2otfA-1h9hE:
undetectable		 2otfA-1h9hE:
17.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ijl PHOSPHOLIPASE A2

(Deinagkistrodon
acutus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
SER A  22
GLY A  29
HIS A  47
 None
None
CA  A 203 (-4.5A)
None
 0.74A 2otfA-1ijlA:
21.0		 2otfA-1ijlA:
52.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j17 TRYPSIN II, ANIONIC

(Rattus
norvegicus) 		PF00089
(Trypsin) 		4 LEU T 155
ILE T  73
SER T  32
GLY T  43
 None
 0.94A 2otfA-1j17T:
undetectable		 2otfA-1j17T:
18.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m8r PHOSPHOLIPASE A2

(Gloydius halys) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
SER A  23
GLY A  30
HIS A  48
 None
BU1  A1003 (-3.0A)
BU1  A1002 (-4.3A)
None
 0.68A 2otfA-1m8rA:
21.0		 2otfA-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m8t PHOSPHOLIPASE A2

(Ophiophagus
hannah) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
SER A  23
GLY A  30
HIS A  48
 HEZ  A1002 (-4.0A)
None
CA  A1001 (-4.3A)
None
 0.48A 2otfA-1m8tA:
18.3		 2otfA-1m8tA:
40.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mbq TRYPSIN

(Oncorhynchus
keta) 		PF00089
(Trypsin) 		5 LEU A 155
ILE A  73
SER A  32
GLY A  43
HIS A  29
 None
 1.08A 2otfA-1mbqA:
undetectable		 2otfA-1mbqA:
17.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1p7o PHOSPHOLIPASE A2

(Micropechis
ikaheca) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
SER A  23
GLY A  30
HIS A  48
 None
 0.66A 2otfA-1p7oA:
18.2		 2otfA-1p7oA:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1po0 IRON(III) DICITRATE
TRANSPORT PROTEIN
FECA PRECURSOR

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 LEU A 411
ILE A 471
SER A 473
GLY A 443
 None
 1.01A 2otfA-1po0A:
undetectable		 2otfA-1po0A:
9.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pp2 CALCIUM-FREE
PHOSPHOLIPASE A2

(Crotalus atrox) 		no annotation 4 LEU R   2
SER R  23
GLY R  30
HIS R  48
 None
 0.87A 2otfA-1pp2R:
21.5		 2otfA-1pp2R:
54.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA

(Daboia russelii) 		PF00068
(Phospholip_A2_1) 		5 LEU A   2
ILE A  19
SER A  23
GLY A  30
HIS A  48
 None
 0.74A 2otfA-1q6vA:
25.4		 2otfA-1q6vA:
95.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rni ORF904

(Sulfolobus
islandicus) 		PF09250
(Prim-Pol) 		4 LEU A 149
ILE A 153
SER A 174
GLY A 102
 None
 0.89A 2otfA-1rniA:
undetectable		 2otfA-1rniA:
21.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG

(Agkistrodon
contortrix) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
ILE A  19
GLY A  30
HIS A  48
 None
 0.74A 2otfA-1s8hA:
21.1		 2otfA-1s8hA:
64.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1th7 SMALL NUCLEAR
RIBOPROTEIN PROTEIN

(Sulfolobus
solfataricus) 		PF01423
(LSM) 		4 LEU A  45
ILE A  65
SER A  50
GLY A  34
 None
 0.98A 2otfA-1th7A:
undetectable		 2otfA-1th7A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3t ALCOHOL
DEHYDROGENASE ALPHA
CHAIN

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 345
ILE A 172
SER A 177
GLY A 179
 None
 0.95A 2otfA-1u3tA:
undetectable		 2otfA-1u3tA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u5q SERINE/THREONINE
PROTEIN KINASE TAO2

(Rattus
norvegicus) 		PF00069
(Pkinase) 		4 LEU A 211
ILE A 157
GLY A 138
HIS A 143
 None
 0.97A 2otfA-1u5qA:
undetectable		 2otfA-1u5qA:
14.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vap PHOSPHOLIPASE A2

(Agkistrodon
piscivorus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
SER A  22
GLY A  29
HIS A  47
 None
 0.39A 2otfA-1vapA:
21.8		 2otfA-1vapA:
60.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1b CRTF-RELATED PROTEIN

(Chlorobaculum
tepidum) 		PF00891
(Methyltransf_2) 		4 LEU A 201
ILE A 205
GLY A 178
HIS A 150
 SAH  A4261 (-4.0A)
None
SAH  A4261 ( 4.2A)
SAH  A4261 (-3.6A)
 1.02A 2otfA-1x1bA:
undetectable		 2otfA-1x1bA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xi8 MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN

(Pyrococcus
furiosus) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		4 LEU A 369
ILE A 365
SER A 363
GLY A 362
 None
 1.02A 2otfA-1xi8A:
undetectable		 2otfA-1xi8A:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y7r HYPOTHETICAL PROTEIN
SA2161

(Staphylococcus
aureus) 		PF13673
(Acetyltransf_10) 		4 LEU A  39
ILE A  92
SER A  96
GLY A  61
 None
 0.96A 2otfA-1y7rA:
undetectable		 2otfA-1y7rA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1a INTERFERON-INDUCED,
DOUBLE-STRANDED
RNA-ACTIVATED
PROTEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU B 474
ILE B 420
GLY B 401
HIS B 406
 None
 0.95A 2otfA-2a1aB:
undetectable		 2otfA-2a1aB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buj SERINE/THREONINE-PRO
TEIN KINASE 16

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 221
ILE A 154
GLY A 135
HIS A 140
 None
 0.71A 2otfA-2bujA:
undetectable		 2otfA-2bujA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddz 190AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF04017
(DUF366) 		4 LEU A 154
ILE A 113
SER A 121
GLY A 137
 None
 1.02A 2otfA-2ddzA:
undetectable		 2otfA-2ddzA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eek TRYPSIN-1

(Gadus morhua) 		PF00089
(Trypsin) 		5 LEU A 155
ILE A  73
SER A  32
GLY A  43
HIS A  29
 None
 1.08A 2otfA-2eekA:
undetectable		 2otfA-2eekA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gcd SERINE/THREONINE-PRO
TEIN KINASE TAO2

(Rattus
norvegicus) 		PF00069
(Pkinase) 		4 LEU A 211
ILE A 157
GLY A 138
HIS A 143
 None
 0.88A 2otfA-2gcdA:
undetectable		 2otfA-2gcdA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hwk HELICASE NSP2

(Venezuelan
equine
encephalitis
virus) 		PF01707
(Peptidase_C9) 		4 LEU A 780
ILE A 733
GLY A 721
HIS A 689
 None
 0.94A 2otfA-2hwkA:
undetectable		 2otfA-2hwkA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpn INNER MEMBRANE
PROTEIN YGAP

(Escherichia
coli) 		PF11127
(DUF2892) 		4 LEU A 163
ILE A 118
SER A 158
GLY A 156
 None
 0.97A 2otfA-2mpnA:
undetectable		 2otfA-2mpnA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oq5 TRANSMEMBRANE
PROTEASE, SERINE 11E

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU A 155
ILE A  75
SER A  32
GLY A  43
 None
 0.97A 2otfA-2oq5A:
undetectable		 2otfA-2oq5A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2php UNCHARACTERIZED
PROTEIN MJ0236

(Methanocaldococcus
jannaschii) 		PF10120
(ThiP_synth) 		4 LEU A 320
ILE A 315
SER A 312
GLY A 310
 None
None
CL  A   6 (-2.9A)
None
 0.97A 2otfA-2phpA:
undetectable		 2otfA-2phpA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgy ENOLASE FROM THE
ENVIRONMENTAL GENOME
SHOTGUN SEQUENCING
OF THE SARGASSO SEA

(-) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 126
ILE A  80
SER A 114
GLY A 115
 None
 1.01A 2otfA-2qgyA:
undetectable		 2otfA-2qgyA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvb HALOALKANE
DEHALOGENASE 3

(Mycobacterium
tuberculosis) 		PF00561
(Abhydrolase_1) 		4 LEU A 224
ILE A 135
SER A 112
GLY A 115
 None
 0.71A 2otfA-2qvbA:
undetectable		 2otfA-2qvbA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vc2 INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF13517
(VCBS) 		4 LEU A 306
ILE A 360
SER A 292
GLY A 290
 None
 0.89A 2otfA-2vc2A:
undetectable		 2otfA-2vc2A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpn PERIPLASMIC
SUBSTRATE BINDING
PROTEIN

(Halomonas
elongata) 		PF03480
(DctP) 		4 ILE A 186
SER A 250
GLY A 248
HIS A 245
 None
 1.01A 2otfA-2vpnA:
undetectable		 2otfA-2vpnA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yh2 ESTERASE

(Pyrobaculum
calidifontis) 		PF07859
(Abhydrolase_3) 		4 LEU A  11
ILE A   6
SER A   4
GLY A 281
 None
 0.81A 2otfA-2yh2A:
undetectable		 2otfA-2yh2A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z2w WEE1-LIKE PROTEIN
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 503
ILE A 432
GLY A 413
HIS A 418
 None
 0.84A 2otfA-2z2wA:
undetectable		 2otfA-2z2wA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aay PUTATIVE THIOSULFATE
SULFURTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00581
(Rhodanese) 		4 LEU A   7
ILE A  81
GLY A 112
HIS A 241
 None
 0.98A 2otfA-3aayA:
undetectable		 2otfA-3aayA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpr DIHYDRODIPICOLINATE
SYNTHETASE

(Corynebacterium
glutamicum) 		PF00701
(DHDPS) 		4 ILE A  89
SER A  53
GLY A  21
HIS A 221
 None
 0.90A 2otfA-3cprA:
undetectable		 2otfA-3cprA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3do6 FORMATE--TETRAHYDROF
OLATE LIGASE

(Thermotoga
maritima) 		PF01268
(FTHFS) 		4 LEU A 105
ILE A  64
SER A 102
GLY A 100
 None
 0.95A 2otfA-3do6A:
undetectable		 2otfA-3do6A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ein GLUTATHIONE
S-TRANSFERASE 1-1

(Drosophila
melanogaster) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A  31
ILE A  53
SER A  10
GLY A   9
 None
GSH  A 210 (-4.3A)
GSH  A 210 (-3.1A)
None
 0.94A 2otfA-3einA:
undetectable		 2otfA-3einA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7j GLUTATHIONE
TRANSFERASE GST1-4

(Anopheles dirus) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 LEU A  30
ILE A  52
SER A   9
GLY A   8
 None
GTX  A 220 (-4.2A)
GTX  A 220 (-3.2A)
GTX  A 220 (-3.7A)
 0.95A 2otfA-3g7jA:
undetectable		 2otfA-3g7jA:
17.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g8g PHOSPHOLIPASE A2,
AMMODYTOXIN A

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
SER A  22
GLY A  29
HIS A  47
 None
 0.95A 2otfA-3g8gA:
22.8		 2otfA-3g8gA:
80.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hfk 4-METHYLMUCONOLACTON
E METHYLISOMERASE

(Pseudomonas
reinekei) 		PF09448
(MmlI) 		4 LEU A  98
ILE A  61
GLY A  65
HIS A  26
 4ML  A 201 ( 4.8A)
None
4ML  A 201 ( 4.2A)
4ML  A 201 (-4.1A)
 0.97A 2otfA-3hfkA:
undetectable		 2otfA-3hfkA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF10

(Schizosaccharomyces
pombe) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF03764
(EFG_IV)
PF16004
(EFTUD2) 		4 LEU B 863
ILE B 889
SER B 894
GLY B 896
 None
 0.98A 2otfA-3jb9B:
undetectable		 2otfA-3jb9B:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1

(Oryctolagus
cuniculus) 		PF00092
(VWA)
PF08399
(VWA_N)
PF08473
(VGCC_alpha2) 		4 LEU F 185
ILE F 180
SER F 178
GLY F 177
 None
 0.92A 2otfA-3jbrF:
undetectable		 2otfA-3jbrF:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3klj NAD(FAD)-DEPENDENT
DEHYDROGENASE,
NIRB-FAMILY
(N-TERMINAL DOMAIN)

(Clostridium
acetobutylicum) 		PF07992
(Pyr_redox_2) 		4 LEU A 188
ILE A 197
SER A 304
GLY A 305
 None
 1.02A 2otfA-3kljA:
undetectable		 2otfA-3kljA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxu TRIPEPTIDYL-PEPTIDAS
E 2

(Drosophila
melanogaster) 		PF00082
(Peptidase_S8)
PF12580
(TPPII)
PF12583
(TPPII_N) 		4 LEU X 474
SER X 281
GLY X 291
HIS X 467
 None
 0.90A 2otfA-3lxuX:
undetectable		 2otfA-3lxuX:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n4p TERMINASE SUBUNIT
UL89 PROTEIN

(Human
betaherpesvirus
5) 		PF02499
(DNA_pack_C) 		4 LEU A 620
ILE A 610
SER A 607
GLY A 491
 None
 0.85A 2otfA-3n4pA:
undetectable		 2otfA-3n4pA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyo G PROTEIN-COUPLED
RECEPTOR KINASE 6

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		4 LEU A 371
ILE A 317
GLY A 298
HIS A 303
 None
 0.94A 2otfA-3nyoA:
undetectable		 2otfA-3nyoA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 ILE A 380
SER A 414
GLY A 415
HIS A 659
 None
None
None
SO4  A1001 (-4.1A)
 0.90A 2otfA-3opyA:
undetectable		 2otfA-3opyA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)

(Doryteuthis
pealeii) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 LEU A 101
ILE A  99
SER A  96
GLY A  95
 None
 0.91A 2otfA-3qr1A:
undetectable		 2otfA-3qr1A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rj8 CARBOHYDRATE OXIDASE

(Microdochium
nivale) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 LEU A 112
SER A 138
GLY A 139
HIS A  70
 None
FAD  A 501 (-3.0A)
FAD  A 501 (-3.2A)
FAD  A 501 (-2.5A)
 1.01A 2otfA-3rj8A:
undetectable		 2otfA-3rj8A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4p INTEGRIN ALPHA-4

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 LEU A 290
ILE A 339
SER A 276
GLY A 274
 None
 0.67A 2otfA-3v4pA:
undetectable		 2otfA-3v4pA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bkw ZINC FINGER FYVE
DOMAIN-CONTAINING
PROTEIN 9

(Homo sapiens) 		PF11979
(DUF3480) 		4 LEU A1120
ILE A1072
SER A1201
GLY A1225
 None
 0.99A 2otfA-4bkwA:
undetectable		 2otfA-4bkwA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwp PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN-3

(Drosophila
melanogaster) 		no annotation 4 LEU A 596
ILE A 554
GLY A 535
HIS A 540
 None
 0.77A 2otfA-4bwpA:
undetectable		 2otfA-4bwpA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 LEU A 306
ILE A 360
SER A 292
GLY A 290
 None
 0.72A 2otfA-4cakA:
undetectable		 2otfA-4cakA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dng UNCHARACTERIZED
ALDEHYDE
DEHYDROGENASE ALDY

(Bacillus
subtilis) 		PF00171
(Aldedh) 		4 LEU A  79
ILE A  90
SER A 185
GLY A 187
 None
 0.83A 2otfA-4dngA:
undetectable		 2otfA-4dngA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecd CHORISMATE SYNTHASE

(Bifidobacterium
longum) 		PF01264
(Chorismate_synt) 		4 LEU A 248
ILE A 234
SER A 304
GLY A 298
 None
 0.93A 2otfA-4ecdA:
undetectable		 2otfA-4ecdA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA

(Azotobacter
vinelandii) 		PF00696
(AA_kinase) 		4 ILE A 165
SER A 163
GLY A 162
HIS B 239
 None
 0.99A 2otfA-4f6tA:
undetectable		 2otfA-4f6tA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbl LIPS LIPOLYTIC
ENZYME

(unidentified) 		PF12146
(Hydrolase_4) 		4 LEU A 113
ILE A  50
SER A  48
GLY A  47
 None
 0.99A 2otfA-4fblA:
undetectable		 2otfA-4fblA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ

(Pseudomonas
fluorescens) 		no annotation 4 LEU A 114
ILE A 132
SER A   2
GLY A  26
 None
 0.88A 2otfA-4fboA:
undetectable		 2otfA-4fboA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwb HALOALKANE
DEHALOGENASE

(Rhodococcus
rhodochrous) 		PF00561
(Abhydrolase_1) 		4 LEU A 221
ILE A 132
SER A 109
GLY A 112
 None
3KP  A2001 (-4.6A)
None
None
 0.91A 2otfA-4fwbA:
undetectable		 2otfA-4fwbA:
14.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4h0s BASIC PHOSPHOLIPASE
A2 HOMOLOG CTS-R6

(Trimeresurus
stejnegeri) 		PF00068
(Phospholip_A2_1) 		5 LEU A   2
ILE A  19
SER A  23
GLY A  30
HIS A  48
 None
 0.77A 2otfA-4h0sA:
20.4		 2otfA-4h0sA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i97 DELTA CLASS 1
GLUTATHIONE
S-TRANSFERASE

(Scaptomyza
nigrita) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A  31
ILE A  53
SER A  10
GLY A   9
 None
GSH  A 301 (-4.2A)
GSH  A 301 ( 4.6A)
None
 1.00A 2otfA-4i97A:
undetectable		 2otfA-4i97A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9c RESPONSE REGULATOR
ASPARTATE
PHOSPHATASE F

(Bacillus
subtilis) 		PF12895
(ANAPC3)
PF13424
(TPR_12) 		4 LEU A  40
ILE A   5
SER A   9
GLY A  11
 None
 0.97A 2otfA-4i9cA:
undetectable		 2otfA-4i9cA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inz SOLUBLE EPOXIDE
HYDROLASE

(Bacillus
megaterium) 		PF00561
(Abhydrolase_1) 		4 LEU A 222
ILE A  72
GLY A 103
HIS A 124
 None
 0.91A 2otfA-4inzA:
undetectable		 2otfA-4inzA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l0m PUTATIVE
5'-METHYLTHIOADENOSI
NE/S-ADENOSYLHOMOCYS
TEINE NUCLEOSIDASE

(Borreliella
burgdorferi) 		PF01048
(PNP_UDP_1) 		4 ILE A 198
SER A  97
GLY A 150
HIS A 148
 None
 0.93A 2otfA-4l0mA:
undetectable		 2otfA-4l0mA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg4 SERINE/THREONINE-PRO
TEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 207
ILE A 152
GLY A 133
HIS A 138
 None
 0.82A 2otfA-4lg4A:
undetectable		 2otfA-4lg4A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ln9 RIFAMYCIN POLYKETIDE
SYNTHASE

(Amycolatopsis
mediterranei) 		PF14765
(PS-DH) 		4 LEU A  47
ILE A  57
GLY A  62
HIS A 215
 None
 1.01A 2otfA-4ln9A:
undetectable		 2otfA-4ln9A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lvo SUBTILISIN-LIKE
SERINE PROTEASE

(Plasmodium
falciparum) 		PF00082
(Peptidase_S8) 		4 LEU A 618
SER A 437
GLY A 448
HIS A 611
 None
 0.95A 2otfA-4lvoA:
undetectable		 2otfA-4lvoA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mk0 BETA-ADRENERGIC
RECEPTOR KINASE 1

(Homo sapiens) 		PF00069
(Pkinase)
PF00169
(PH)
PF00615
(RGS) 		4 LEU A 377
ILE A 323
GLY A 304
HIS A 309
 None
 0.95A 2otfA-4mk0A:
undetectable		 2otfA-4mk0A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mng TRA@ PROTEIN,TRA@
PROTEIN, TI ANTIGEN
CD3-ASSOCIATED
PROTEIN GAMMA CHAIN
V-J-C REGION

(Homo sapiens) 		PF07686
(V-set) 		4 LEU E 221
ILE E 254
SER E 229
GLY E 230
 None
 0.83A 2otfA-4mngE:
undetectable		 2otfA-4mngE:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfu SENESCENCE-ASSOCIATE
D CARBOXYLESTERASE
101

(Arabidopsis
thaliana) 		PF01764
(Lipase_3) 		4 LEU B 157
ILE B 188
GLY B 181
HIS B 200
 None
 1.00A 2otfA-4nfuB:
undetectable		 2otfA-4nfuB:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qs9 HEXOKINASE-1

(Arabidopsis
thaliana) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 LEU A 293
ILE A 318
SER A 410
GLY A 413
 None
 0.96A 2otfA-4qs9A:
undetectable		 2otfA-4qs9A:
13.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rfp ACIDIC PHOSPHOLIPASE
A2 5

(Trimeresurus
stejnegeri) 		PF00068
(Phospholip_A2_1) 		4 ILE A  18
SER A  22
GLY A  29
HIS A  47
 None
 0.87A 2otfA-4rfpA:
20.2		 2otfA-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rfp ACIDIC PHOSPHOLIPASE
A2 5

(Trimeresurus
stejnegeri) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
ILE A  18
SER A  22
GLY A  29
 None
 0.64A 2otfA-4rfpA:
20.2		 2otfA-4rfpA:
53.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgl FILAMENTATION
INDUCED BY CAMP
PROTEIN FIC

(Desulfovibrio
alaskensis) 		PF02661
(Fic) 		4 LEU A 227
ILE A 216
GLY A 192
HIS A 182
 None
None
None
UNL  A 401 ( 4.6A)
 0.88A 2otfA-4rglA:
undetectable		 2otfA-4rglA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnb G PROTEIN-COUPLED
RECEPTOR KINASE 5

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		4 LEU A 371
ILE A 317
GLY A 298
HIS A 303
 None
 0.92A 2otfA-4tnbA:
undetectable		 2otfA-4tnbA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y85 MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 8

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 313
ILE A 259
GLY A 240
HIS A 245
 None
 0.91A 2otfA-4y85A:
undetectable		 2otfA-4y85A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yrp HISTIDYL-TRNA
SYNTHETASE

(Trypanosoma
cruzi) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		4 LEU A 345
ILE A 355
SER A 351
GLY A 350
 None
 0.93A 2otfA-4yrpA:
undetectable		 2otfA-4yrpA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgz ANTIZYME INHIBITOR 1

(Homo sapiens) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 LEU A 232
ILE A  62
SER A 270
GLY A 235
 None
 0.96A 2otfA-4zgzA:
undetectable		 2otfA-4zgzA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b04 PROBABLE TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT BETA
PROBABLE TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT DELTA

(Schizosaccharomyces
pombe) 		PF01008
(IF-2B) 		4 LEU G 364
ILE G 326
SER G 327
GLY C 292
 None
 0.98A 2otfA-5b04G:
undetectable		 2otfA-5b04G:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A

(Cellvibrio
japonicus) 		no annotation 4 LEU A 428
ILE A  55
SER A 417
GLY A 334
 None
 0.83A 2otfA-5fkrA:
undetectable		 2otfA-5fkrA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5glg FUMARATE REDUCTASE 2

(Saccharomyces
cerevisiae) 		PF00890
(FAD_binding_2) 		4 LEU A 175
ILE A  70
SER A  42
GLY A  46
 None
None
FAD  A 602 ( 4.0A)
None
 0.83A 2otfA-5glgA:
undetectable		 2otfA-5glgA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5v FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2

(Escherichia
coli) 		PF02465
(FliD_N)
PF07195
(FliD_C) 		4 LEU A 178
ILE A 121
SER A 148
GLY A 152
 None
 1.01A 2otfA-5h5vA:
undetectable		 2otfA-5h5vA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU W 690
ILE W 733
SER W 732
GLY W 728
 None
 1.01A 2otfA-5o9gW:
undetectable		 2otfA-5o9gW:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oki SISTER CHROMATID
COHESION PROTEIN
DCC1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU C 185
ILE C 230
SER C 171
GLY C 170
 None
 1.01A 2otfA-5okiC:
undetectable		 2otfA-5okiC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuu BETA-ADRENERGIC
RECEPTOR KINASE 1

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		4 LEU A 377
ILE A 323
GLY A 304
HIS A 309
 None
 0.89A 2otfA-5uuuA:
undetectable		 2otfA-5uuuA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vdk WEE1-LIKE PROTEIN
KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 420
ILE A 345
GLY A 326
HIS A 331
 None
 0.84A 2otfA-5vdkA:
undetectable		 2otfA-5vdkA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu7 UNCHARACTERIZED
PROTEIN

(Pyrococcus
horikoshii) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 LEU A 337
ILE A 330
SER A 380
GLY A 381
 None
 0.95A 2otfA-5wu7A:
undetectable		 2otfA-5wu7A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zwp GLUTATHIONE
S-TRANSFERASE 1

(Musca domestica) 		no annotation 4 LEU A  30
ILE A  52
SER A   9
GLY A   8
 None
GSH  A 301 (-4.2A)
GSH  A 301 ( 4.5A)
None
 0.94A 2otfA-5zwpA:
undetectable		 2otfA-5zwpA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ao5 SERINE/THREONINE-PRO
TEIN KINASE 3

(Homo sapiens) 		no annotation 4 LEU A 207
ILE A 152
GLY A 133
HIS A 138
 None
 0.97A 2otfA-6ao5A:
undetectable		 2otfA-6ao5A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC2

(Saccharomyces
cerevisiae) 		no annotation 4 LEU B 347
ILE B 544
SER B 564
GLY B 554
 None
 0.69A 2otfA-6f42B:
undetectable		 2otfA-6f42B:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARD

(Acetobacterium
woodii) 		no annotation 4 LEU B  71
ILE B 203
SER B  86
GLY B  63
 None
 0.98A 2otfA-6fahB:
undetectable		 2otfA-6fahB:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhw GLUCOAMYLASE P

(Amorphotheca
resinae) 		no annotation 4 LEU A 252
ILE A 261
SER A 278
GLY A 281
 None
 0.72A 2otfA-6fhwA:
undetectable		 2otfA-6fhwA:
18.18