SIMILAR PATTERNS OF AMINO ACIDS FOR 2OPX_A_DXCA1003_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee2 ALCOHOL
DEHYDROGENASE

(Equus caballus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 371
ASP A  49
ALA A  69
PHE A 358
 None
 1.00A 2opxA-1ee2A:
4.2		 2opxA-1ee2A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hm6 ANNEXIN 1

(Sus scrofa) 		PF00191
(Annexin) 		4 ILE A 222
LEU A 218
ASP A 259
ALA A 179
 None
 0.96A 2opxA-1hm6A:
undetectable		 2opxA-1hm6A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1irf INTERFERON
REGULATORY FACTOR-2

(Mus musculus) 		PF00605
(IRF) 		4 ILE A  16
LEU A  12
ASP A  51
PHE A  81
 None
 1.06A 2opxA-1irfA:
undetectable		 2opxA-1irfA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jr7 HYPOTHETICAL 37.4
KDA PROTEIN IN
ILEY-GABD INTERGENIC
REGION

(Escherichia
coli) 		PF08943
(CsiD) 		4 ILE A 122
LEU A  83
ALA A 119
PHE A  37
 None
 0.92A 2opxA-1jr7A:
undetectable		 2opxA-1jr7A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsc ACETOHYDROXY-ACID
SYNTHASE

(Saccharomyces
cerevisiae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ILE A 477
LEU A 480
ASP A 546
ALA A 504
 None
 0.91A 2opxA-1jscA:
undetectable		 2opxA-1jscA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ka9 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE

(Thermus
thermophilus) 		PF00977
(His_biosynth) 		4 ILE F 235
LEU F 238
ALA F  45
PHE F 215
 None
 1.01A 2opxA-1ka9F:
undetectable		 2opxA-1ka9F:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m5y SURVIVAL PROTEIN
SURA

(Escherichia
coli) 		PF00639
(Rotamase)
PF09312
(SurA_N)
PF13616
(Rotamase_3) 		4 ILE A 290
LEU A 377
ASP A 313
ALA A 324
 None
 0.96A 2opxA-1m5yA:
undetectable		 2opxA-1m5yA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v10 LACCASE

(Rigidoporus
microporus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 345
LEU A 332
ALA A 463
PHE A 438
 None
 0.70A 2opxA-1v10A:
undetectable		 2opxA-1v10A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w07 ACYL-COA OXIDASE

(Arabidopsis
thaliana) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		4 ILE A  76
LEU A  81
ASP A  45
ALA A  72
 None
 1.06A 2opxA-1w07A:
undetectable		 2opxA-1w07A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvt BETA-1,4-MANNANASE

(Cellulomonas
fimi) 		PF02156
(Glyco_hydro_26) 		4 ILE A   6
LEU A  21
ASP A  10
ALA A 368
 None
 1.01A 2opxA-2bvtA:
undetectable		 2opxA-2bvtA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6m WERNER SYNDROME
ATP-DEPENDENT
HELICASE HOMOLOG

(Mus musculus) 		PF01612
(DNA_pol_A_exo1) 		4 ILE A 217
LEU A 155
ASP A  76
ALA A 213
 None
 1.06A 2opxA-2e6mA:
undetectable		 2opxA-2e6mA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eb0 MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Methanocaldococcus
jannaschii) 		PF01368
(DHH)
PF02833
(DHHA2) 		4 LEU A 141
ASP A 160
ALA A 114
PHE A 151
 None
 1.04A 2opxA-2eb0A:
undetectable		 2opxA-2eb0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fbv WERNER SYNDROME
HELICASE

(Homo sapiens) 		PF01612
(DNA_pol_A_exo1) 		4 ILE A 223
LEU A 161
ASP A  82
ALA A 219
 None
None
MN  A 238 ( 2.8A)
None
 0.99A 2opxA-2fbvA:
undetectable		 2opxA-2fbvA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6h HYPOTHETICAL PROTEIN
ATU0120

(Agrobacterium
fabrum) 		PF06041
(DUF924) 		4 ILE A  12
LEU A  66
ALA A   9
PHE A 113
 None
 0.80A 2opxA-2i6hA:
undetectable		 2opxA-2i6hA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibu ACETYL-COA
ACETYLTRANSFERASE

(Homo sapiens) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 ILE A 206
LEU A 361
ASP A 212
ALA A 207
 None
None
None
GOL  A4001 ( 4.4A)
 0.98A 2opxA-2ibuA:
undetectable		 2opxA-2ibuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2id3 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		PF00440
(TetR_N)
PF16859
(TetR_C_11) 		4 ILE A  44
LEU A  41
ASP A  68
ALA A  27
 None
CL  A 611 (-3.8A)
None
None
 0.95A 2opxA-2id3A:
undetectable		 2opxA-2id3A:
20.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ilu ALDEHYDE
DEHYDROGENASE A

(Escherichia
coli) 		PF00171
(Aldedh) 		4 ILE A  97
LEU A 100
ASP A 275
ALA A 324
 None
 0.59A 2opxA-2iluA:
62.7		 2opxA-2iluA:
99.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inc TOUB PROTEIN

(Pseudomonas
stutzeri) 		PF06234
(TmoB) 		4 ILE C  81
LEU C  79
ASP C  25
ALA C  31
 None
 0.98A 2opxA-2incC:
undetectable		 2opxA-2incC:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j86 PROTEIN
SERINE-THREONINE
PHOSPHATASE

(Synechococcus
elongatus) 		PF13672
(PP2C_2) 		4 ILE A  83
LEU A 167
ASP A  34
ALA A  45
 None
None
MG  A1242 ( 2.1A)
None
 0.96A 2opxA-2j86A:
undetectable		 2opxA-2j86A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lw4 TRANSCRIPTION
ELONGATION FACTOR A
PROTEIN 2

(Homo sapiens) 		PF07500
(TFIIS_M) 		4 ILE A  33
LEU A  83
ASP A  27
ALA A  32
 None
 0.99A 2opxA-2lw4A:
undetectable		 2opxA-2lw4A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o04 PECTATE LYASE

(Bacillus
subtilis) 		PF00544
(Pec_lyase_C) 		4 ILE A 357
LEU A 352
ALA A 359
PHE A 306
 None
 0.76A 2opxA-2o04A:
undetectable		 2opxA-2o04A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wq4 LECTIN

(Burkholderia
cenocepacia) 		no annotation 4 ILE A  61
LEU A  42
ASP A  20
ALA A  62
 None
 0.89A 2opxA-2wq4A:
undetectable		 2opxA-2wq4A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsk GLYCOGEN DEBRANCHING
ENZYME

(Escherichia
coli) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 ILE A 256
LEU A 251
ALA A 195
PHE A 244
 None
 1.01A 2opxA-2wskA:
undetectable		 2opxA-2wskA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y4l MANNOSYLGLYCERATE
SYNTHASE

(Rhodothermus
marinus) 		no annotation 4 LEU A 278
ASP A 224
ALA A 273
PHE A 341
 None
 1.00A 2opxA-2y4lA:
3.8		 2opxA-2y4lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbz CYTOCHROME P450-SU1

(Streptomyces
griseolus) 		PF00067
(p450) 		4 ILE A 235
LEU A 200
ASP A 195
PHE A 172
 None
 0.99A 2opxA-2zbzA:
undetectable		 2opxA-2zbzA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5v ALPHA-GALACTOSIDASE

(Umbelopsis
vinacea) 		PF16499
(Melibiase_2) 		4 ILE A  35
LEU A  40
ASP A 273
ALA A  31
 None
 1.00A 2opxA-3a5vA:
undetectable		 2opxA-3a5vA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6g CYTOCHROME P450 2R1

(Homo sapiens) 		PF00067
(p450) 		4 ILE A  52
LEU A  81
ALA A 224
PHE A 380
 None
None
UNX  A   2 ( 3.7A)
None
 0.95A 2opxA-3c6gA:
undetectable		 2opxA-3c6gA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3djc TYPE III
PANTOTHENATE KINASE

(Legionella
pneumophila) 		PF03309
(Pan_kinase) 		4 ILE A 114
LEU A 249
ALA A 111
PHE A  17
 None
 0.87A 2opxA-3djcA:
undetectable		 2opxA-3djcA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dpi NAD+ SYNTHETASE

(Burkholderia
pseudomallei) 		PF02540
(NAD_synthase) 		4 ILE A  33
LEU A  67
ALA A  29
PHE A 103
 None
 0.93A 2opxA-3dpiA:
undetectable		 2opxA-3dpiA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9y ACETOLACTATE
SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ILE A 468
LEU A 471
ASP A 534
ALA A 492
 None
 0.91A 2opxA-3e9yA:
undetectable		 2opxA-3e9yA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fbz PUTATIVE
UNCHARACTERIZED
PROTEIN

(Acidianus
filamentous
virus 1) 		no annotation 4 ILE A  63
LEU A  64
ASP A 120
ALA A 126
 None
 1.01A 2opxA-3fbzA:
undetectable		 2opxA-3fbzA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fi1 NA(+)/H(+)
ANTIPORTER NHAA

(Escherichia
coli) 		PF06965
(Na_H_antiport_1) 		4 LEU A 348
ASP A 164
ALA A 127
PHE A  72
 None
 1.00A 2opxA-3fi1A:
undetectable		 2opxA-3fi1A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3it4 ARGININE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
ARGJ BETA CHAIN

(Mycobacterium
tuberculosis) 		PF01960
(ArgJ) 		4 ILE B 335
LEU B 337
ASP B 376
ALA B 299
 None
 0.93A 2opxA-3it4B:
undetectable		 2opxA-3it4B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kos HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR

(Citrobacter
freundii) 		PF03466
(LysR_substrate) 		4 ILE A 123
LEU A 125
ASP A 142
ALA A 277
 None
None
GOL  A   2 (-2.6A)
None
 0.97A 2opxA-3kosA:
undetectable		 2opxA-3kosA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lsc TRIAZINE HYDROLASE

(Paenarthrobacter
aurescens) 		PF01979
(Amidohydro_1) 		4 ILE A 206
LEU A 191
ALA A 207
PHE A 133
 None
 1.02A 2opxA-3lscA:
undetectable		 2opxA-3lscA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m03 ORIGIN RECOGNITION
COMPLEX SUBUNIT 6

(Homo sapiens) 		no annotation 4 ILE A 117
LEU A 179
ALA A 114
PHE A 172
 None
 0.90A 2opxA-3m03A:
undetectable		 2opxA-3m03A:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdq EXOPOLYPHOSPHATASE

(Cytophaga
hutchinsonii) 		PF02541
(Ppx-GppA) 		4 ILE A 117
LEU A 298
ASP A 109
ALA A 114
 None
None
CL  A 315 ( 4.1A)
None
 1.05A 2opxA-3mdqA:
undetectable		 2opxA-3mdqA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Sinorhizobium
meliloti) 		PF03466
(LysR_substrate) 		4 ILE A 102
LEU A 105
ALA A  97
PHE A 281
 None
 0.95A 2opxA-3mz1A:
undetectable		 2opxA-3mz1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ns4 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 53

(Saccharomyces
cerevisiae) 		PF16854
(VPS53_C) 		4 ILE A 666
LEU A 669
ASP A 584
ALA A 662
 None
 0.95A 2opxA-3ns4A:
undetectable		 2opxA-3ns4A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opx PROTEIN SSM1

(Saccharomyces
cerevisiae) 		PF13419
(HAD_2) 		4 ILE A  86
LEU A  84
ASP A 167
ALA A  97
 None
U5P  A 265 (-4.9A)
None
None
 0.96A 2opxA-3opxA:
2.4		 2opxA-3opxA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz6 LEUCYL-TRNA
SYNTHETASE

(Giardia
intestinalis) 		PF00133
(tRNA-synt_1) 		4 ILE A 510
LEU A 507
ASP A 444
ALA A 489
 None
 0.86A 2opxA-3pz6A:
undetectable		 2opxA-3pz6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdq 4-HYDROXYBUTYRATE
COA-TRANSFERASE

(Clostridium
aminobutyricum) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 ILE A 109
ASP A 139
ALA A 144
PHE A 102
 None
 1.06A 2opxA-3qdqA:
undetectable		 2opxA-3qdqA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rim TRANSKETOLASE

(Mycobacterium
tuberculosis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ILE A  92
LEU A  33
ASP A  28
PHE A 301
 None
 1.06A 2opxA-3rimA:
undetectable		 2opxA-3rimA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si1 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE

(Mus musculus) 		PF04389
(Peptidase_M28) 		4 ILE A 345
LEU A 348
ASP A 287
ALA A 342
 None
 1.05A 2opxA-3si1A:
undetectable		 2opxA-3si1A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE

(Vibrio cholerae) 		PF00579
(tRNA-synt_1b) 		4 ILE A 160
LEU A  95
ASP A 135
ALA A 157
 None
None
TRP  A 401 (-4.0A)
None
 1.04A 2opxA-3sz3A:
undetectable		 2opxA-3sz3A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vjz PUTATIVE
UNCHARACTERIZED
PROTEIN

(Neisseria
meningitidis) 		PF14300
(DUF4375) 		4 ILE A  89
LEU A 148
ASP A  44
PHE A 159
 None
 1.06A 2opxA-3vjzA:
undetectable		 2opxA-3vjzA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr5 V-TYPE SODIUM ATPASE
SUBUNIT B

(Enterococcus
hirae) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 ILE D 111
LEU D  79
ASP D  91
ALA D 223
 None
 0.87A 2opxA-3vr5D:
undetectable		 2opxA-3vr5D:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4c CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1

(Homo sapiens) 		no annotation 4 ILE A1310
LEU A1313
ASP A1258
ALA A1306
 None
 0.95A 2opxA-4b4cA:
undetectable		 2opxA-4b4cA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d70 SORTASE FAMILY
PROTEIN

(Clostridium
perfringens) 		PF04203
(Sortase) 		4 ILE A 143
LEU A 124
ALA A 183
PHE A 118
 None
 1.04A 2opxA-4d70A:
undetectable		 2opxA-4d70A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ee9 ENDOGLUCANASE

(uncultured
bacterium) 		PF00150
(Cellulase) 		4 ILE A 166
LEU A 164
ASP A 153
ALA A 148
 None
 0.93A 2opxA-4ee9A:
undetectable		 2opxA-4ee9A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emy AMINOTRANSFERASE
CLASS I AND II

(Anaerococcus
prevotii) 		PF00155
(Aminotran_1_2) 		4 ILE A 102
LEU A 287
ALA A 101
PHE A 249
 None
 1.05A 2opxA-4emyA:
undetectable		 2opxA-4emyA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2p CHAPERONE SURA

(Salmonella
enterica) 		PF13616
(Rotamase_3) 		4 ILE A 290
LEU A 377
ASP A 313
ALA A 324
 None
 0.99A 2opxA-4g2pA:
undetectable		 2opxA-4g2pA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jyl ENOYL-COA HYDRATASE

(Thermoplasma
volcanium) 		PF00378
(ECH_1) 		4 ILE A  84
LEU A  33
ALA A  85
PHE A  57
 None
 0.97A 2opxA-4jylA:
undetectable		 2opxA-4jylA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l4q S-ADENOSYLMETHIONINE
SYNTHASE

(Thermococcus
kodakarensis) 		PF01941
(AdoMet_Synthase) 		4 ILE A 346
LEU A 324
ASP A 384
ALA A 360
 None
 0.96A 2opxA-4l4qA:
undetectable		 2opxA-4l4qA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9z MALYL-COA LYASE

(Rhodobacter
sphaeroides) 		PF03328
(HpcH_HpaI) 		5 ILE A 124
LEU A  93
ASP A 118
ALA A 123
PHE A 136
 None
 1.45A 2opxA-4l9zA:
undetectable		 2opxA-4l9zA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B

(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		PF02502
(LacAB_rpiB)
PF02502
(LacAB_rpiB) 		4 ILE B 141
LEU B 137
ASP A  63
ALA A  72
 None
 1.02A 2opxA-4lfnB:
3.8		 2opxA-4lfnB:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll6 MYOSIN-4

(Saccharomyces
cerevisiae) 		PF01843
(DIL) 		4 ILE A1253
LEU A1276
ALA A1249
PHE A1342
 None
 0.78A 2opxA-4ll6A:
undetectable		 2opxA-4ll6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mjk CRISPR PROTEIN

(Archaeoglobus
fulgidus) 		PF09704
(Cas_Cas5d) 		4 ILE A 147
LEU A 144
ALA A  39
PHE A 134
 None
 0.98A 2opxA-4mjkA:
undetectable		 2opxA-4mjkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o0l NADPH-DEPENDENT
3-QUINUCLIDINONE
REDUCTASE

(Rhodotorula
mucilaginosa) 		PF13561
(adh_short_C2) 		4 ILE A 162
LEU A 250
ASP A 262
ALA A 163
 None
 0.93A 2opxA-4o0lA:
5.6		 2opxA-4o0lA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfy ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 ILE A 381
LEU A 429
ALA A 398
PHE A 294
 None
 1.02A 2opxA-4pfyA:
undetectable		 2opxA-4pfyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4py9 PUTATIVE
EXOPOLYPHOSPHATASE-R
ELATED PROTEIN

(Bacteroides
fragilis) 		PF01368
(DHH) 		4 ILE A   6
LEU A 152
ASP A  12
ALA A   7
 NA  A 407 (-4.2A)
None
None
None
 1.00A 2opxA-4py9A:
2.9		 2opxA-4py9A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pyr PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC TRANSPORTER

(Chromobacterium
violaceum) 		PF04348
(LppC) 		4 ILE A 302
LEU A 195
ASP A 202
ALA A 378
 None
 1.05A 2opxA-4pyrA:
3.6		 2opxA-4pyrA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3u 2-HYDROXYISOBUTYRYL-
COA MUTASE LARGE
SUBUNIT

(Aquincola
tertiaricarbonis) 		PF01642
(MM_CoA_mutase) 		4 ILE A 144
LEU A 153
ASP A  98
ALA A 143
 None
 1.01A 2opxA-4r3uA:
undetectable		 2opxA-4r3uA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r70 BACTERIOPHYTOCHROME
(LIGHT-REGULATED
SIGNAL TRANSDUCTION
HISTIDINE KINASE),
PHYB2

(Rhodopseudomonas
palustris) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 ILE A  39
LEU A  45
ASP A 246
ALA A  38
 None
 1.05A 2opxA-4r70A:
undetectable		 2opxA-4r70A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uii GGDEF DOMAIN PROTEIN

(Azotobacter
vinelandii) 		PF11563
(Protoglobin) 		4 ILE A  91
LEU A  90
ASP A  83
ALA A  10
 None
 1.07A 2opxA-4uiiA:
undetectable		 2opxA-4uiiA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ykn PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT
ALPHA,PHOSPHATIDYLIN
OSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM FUSION
PROTEIN

(Homo sapiens) 		PF00017
(SH2)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B)
PF16454
(PI3K_P85_iSH2) 		4 ILE A1393
LEU A1396
ASP A1390
ALA A1333
 None
 0.94A 2opxA-4yknA:
undetectable		 2opxA-4yknA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yr1 ALKALINE PHOSPHATASE

(Escherichia
coli) 		PF00245
(Alk_phosphatase) 		4 ILE A  46
LEU A 319
ASP A 304
ALA A 352
 None
 1.01A 2opxA-4yr1A:
undetectable		 2opxA-4yr1A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b37 TRYPTOPHAN
DEHYDROGENASE

(Nostoc
punctiforme) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A 317
LEU A 314
ASP A 280
ALA A 332
 None
 1.01A 2opxA-5b37A:
3.4		 2opxA-5b37A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu9 BETA-N-ACETYLHEXOSAM
INIDASE

(Beutenbergia
cavernae) 		PF00933
(Glyco_hydro_3) 		4 ILE A 194
LEU A 189
ALA A 145
PHE A 238
 None
 0.85A 2opxA-5bu9A:
undetectable		 2opxA-5bu9A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c0y EXOSOME COMPLEX
EXONUCLEASE RRP6

(Saccharomyces
cerevisiae) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		4 ILE A 297
LEU A 300
ASP A 238
ALA A 293
 None
 0.96A 2opxA-5c0yA:
undetectable		 2opxA-5c0yA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c70 GLUCURONIDASE

(Aspergillus
oryzae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 ILE A 501
LEU A 464
ASP A 498
ALA A 543
 None
 0.89A 2opxA-5c70A:
undetectable		 2opxA-5c70A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cm9 RAL GUANINE
NUCLEOTIDE
DISSOCIATION
STIMULATOR-LIKE 2

(Mus musculus) 		PF00617
(RasGEF)
PF00618
(RasGEF_N) 		4 ILE A 160
LEU A 207
ALA A 159
PHE A 174
 None
 1.03A 2opxA-5cm9A:
undetectable		 2opxA-5cm9A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqn CYTOCHROME P450
CYP125

(Mycolicibacterium
smegmatis) 		PF00067
(p450) 		4 ILE A 162
LEU A 248
ALA A 163
PHE A 241
 None
HEM  A 501 (-4.5A)
None
None
 1.05A 2opxA-5dqnA:
undetectable		 2opxA-5dqnA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fll 6-CARBOXYHEXANOATE-C
OA LIGASE

(Bacillus
subtilis) 		PF03744
(BioW) 		4 ILE A 231
LEU A 127
ASP A 243
ALA A 186
 None
 0.79A 2opxA-5fllA:
undetectable		 2opxA-5fllA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frt DIMERIC (2FE-2S)
PROTEIN

(Azotobacter
vinelandii) 		PF00111
(Fer2) 		4 ILE A   4
LEU A 111
ASP A 108
ALA A  19
 None
 0.95A 2opxA-5frtA:
undetectable		 2opxA-5frtA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6

(Homo sapiens) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 ILE B 961
LEU B 959
ALA B 992
PHE B 935
 None
 1.02A 2opxA-5gjeB:
undetectable		 2opxA-5gjeB:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5go6 PUTATIVE SECRETED
PROTEIN

(Streptomyces
avermitilis) 		PF04203
(Sortase) 		4 ILE A 162
LEU A 143
ALA A 212
PHE A 137
 None
 1.04A 2opxA-5go6A:
undetectable		 2opxA-5go6A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gq1 GENOME POLYPROTEIN

(Enterovirus A) 		PF00910
(RNA_helicase) 		4 ILE A 146
LEU A 310
ASP A 304
ALA A 145
 None
 1.01A 2opxA-5gq1A:
undetectable		 2opxA-5gq1A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		4 ILE A 850
LEU A 841
ASP A 759
ALA A 895
 None
None
G1P  A1201 (-4.5A)
None
 1.01A 2opxA-5h42A:
undetectable		 2opxA-5h42A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hfj ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA)

(Helicobacter
pylori) 		PF01555
(N6_N4_Mtase) 		4 ILE A  12
ASP A 193
ALA A   9
PHE A 212
 None
None
SAM  A 301 (-3.2A)
None
 1.03A 2opxA-5hfjA:
2.1		 2opxA-5hfjA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hke BILE SALT HYDROLASE

(Lactobacillus
salivarius) 		PF02275
(CBAH) 		4 ILE A 106
LEU A 107
ASP A 145
ALA A 116
 None
 1.06A 2opxA-5hkeA:
undetectable		 2opxA-5hkeA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz3 PREDICTED PROTEIN

(Physcomitrella
patens) 		PF00316
(FBPase) 		4 ILE B 111
LEU B 108
ASP B 178
ALA B 140
 None
 1.02A 2opxA-5iz3B:
undetectable		 2opxA-5iz3B:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jf0 PEPTIDE DEFORMYLASE

(Streptococcus
agalactiae) 		PF01327
(Pep_deformylase) 		4 ILE A   4
LEU A  45
ASP A  18
ALA A   3
 None
None
NI  A 307 (-1.9A)
None
 1.04A 2opxA-5jf0A:
undetectable		 2opxA-5jf0A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k7v DESIGNED PROTEIN
HR00C3

(synthetic
construct) 		no annotation 4 ILE A  74
LEU A  77
ASP A  10
ALA A  70
 None
 1.02A 2opxA-5k7vA:
undetectable		 2opxA-5k7vA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mjv CAPSID SUBUNIT VP0

(Parechovirus A) 		PF00073
(Rhv) 		4 ILE C 253
LEU C 251
ASP C 262
ALA C 258
 None
 0.82A 2opxA-5mjvC:
undetectable		 2opxA-5mjvC:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mll DNA PROCESSING CHAIN
A (DPRA)

(Helicobacter
pylori) 		no annotation 4 ILE A  76
LEU A  69
ALA A  47
PHE A 210
 None
 1.05A 2opxA-5mllA:
2.2		 2opxA-5mllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mmh HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR AMPR

(Pseudomonas
aeruginosa) 		PF03466
(LysR_substrate) 		4 ILE A 123
LEU A 125
ASP A 142
ALA A 277
 None
 0.99A 2opxA-5mmhA:
undetectable		 2opxA-5mmhA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nl6 CALPONIN DOMAIN
FAMILY PROTEIN

(Entamoeba
histolytica) 		no annotation 4 ILE A 427
LEU A 424
ASP A 451
ALA A 380
 None
 1.03A 2opxA-5nl6A:
undetectable		 2opxA-5nl6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odo ISOMERASE

(Rhodococcus
erythropolis) 		no annotation 4 LEU A 337
ASP A 296
ALA A 505
PHE A 257
 None
 0.95A 2opxA-5odoA:
2.3		 2opxA-5odoA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9l PARALOG OF
ACCUMULATION AND
REPLICATION OF
CHLOROPLASTS 6
(PARC6)

(Arabidopsis
thaliana) 		no annotation 4 ILE A 769
LEU A 696
ASP A 689
ALA A 755
 None
 1.02A 2opxA-5u9lA:
undetectable		 2opxA-5u9lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ufh LACI-TYPE
TRANSCRIPTIONAL
REGULATOR

(Bifidobacterium
animalis) 		PF13377
(Peripla_BP_3) 		4 ILE A  69
LEU A  67
ASP A  82
ALA A  77
 None
 1.04A 2opxA-5ufhA:
3.2		 2opxA-5ufhA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8c TRANSCRIPTIONAL
REGULATOR

(Actinomyces
oris) 		no annotation 4 ILE A 207
LEU A 232
ASP A 210
ALA A 276
 None
 1.03A 2opxA-5v8cA:
undetectable		 2opxA-5v8cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX

(unidentified) 		no annotation 4 ILE A 460
LEU A 463
ASP A 495
PHE A 448
 None
 0.80A 2opxA-5vqdA:
undetectable		 2opxA-5vqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x2q TASTE RECEPTOR, TYPE
1, MEMBER 2A

(Oryzias latipes) 		PF01094
(ANF_receptor) 		4 ILE A 326
LEU A 358
ALA A 329
PHE A  63
 None
 1.06A 2opxA-5x2qA:
3.2		 2opxA-5x2qA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y59 ATP-DEPENDENT DNA
HELICASE II SUBUNIT
2

(Saccharomyces
cerevisiae) 		no annotation 4 ILE B 183
LEU B 154
ASP B 148
ALA B 182
 None
 1.03A 2opxA-5y59B:
undetectable		 2opxA-5y59B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		4 ILE A 303
LEU A 313
ASP A 919
ALA A 300
 None
 0.74A 2opxA-5y7oA:
undetectable		 2opxA-5y7oA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7r IRON/ALPHA-KETOGLUTA
RATE-DEPENDENT
DIOXYGENASE ASQJ

(Aspergillus
nidulans) 		no annotation 4 ILE B 283
LEU B 276
ASP B 113
ALA B 263
 None
 1.00A 2opxA-5y7rB:
undetectable		 2opxA-5y7rB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4j NUCLEOPORIN GLE1

(Homo sapiens) 		no annotation 4 ILE B 581
LEU B 598
ALA B 578
PHE B 641
 None
 0.85A 2opxA-6b4jB:
undetectable		 2opxA-6b4jB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8v COENZYME PQQ
SYNTHESIS PROTEIN E

(Methylobacterium
extorquens) 		no annotation 4 ILE A 233
LEU A 188
ASP A 178
ALA A 223
 None
 1.04A 2opxA-6c8vA:
undetectable		 2opxA-6c8vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exs PEPTIDE ABC
TRANSPORTER PERMEASE

(Staphylococcus
hominis) 		no annotation 4 ILE A  62
LEU A  60
ALA A  67
PHE A 190
 None
 0.99A 2opxA-6exsA:
undetectable		 2opxA-6exsA:
undetectable