SIMILAR PATTERNS OF AMINO ACIDS FOR 2OAX_F_SNLF6001_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a27 17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE

(Homo sapiens) 		PF00106
(adh_short) 		4 LEU A  87
LEU A   6
LEU A  36
MET A 121
 None
 1.08A 2oaxF-1a27A:
0.0		 2oaxF-1a27A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cfz HYDROGENASE 2
MATURATION PROTEASE

(Escherichia
coli) 		PF01750
(HycI) 		4 LEU A 104
LEU A 101
LEU A  95
MET A  52
 None
 0.92A 2oaxF-1cfzA:
0.0		 2oaxF-1cfzA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0x D-LACTATE
DEHYDROGENASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF09330
(Lact-deh-memb) 		4 LEU A 510
LEU A 456
LEU A 485
MET A 514
 None
 1.07A 2oaxF-1f0xA:
0.0		 2oaxF-1f0xA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7j PROTEIN YCIO

(Escherichia
coli) 		PF01300
(Sua5_yciO_yrdC) 		4 LEU A 187
LEU A 101
LEU A  67
MET A  89
 None
 0.97A 2oaxF-1k7jA:
0.0		 2oaxF-1k7jA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n76 LACTOFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		4 LEU A 298
LEU A 299
LEU A 271
MET A  26
 None
 1.01A 2oaxF-1n76A:
0.0		 2oaxF-1n76A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrj SIGNAL RECOGNITION
PARTICLE RECEPTOR
ALPHA SUBUNIT
HOMOLOG

(Saccharomyces
cerevisiae) 		PF09201
(SRX) 		4 LEU A  60
LEU A  76
LEU A   5
MET A   1
 None
 1.11A 2oaxF-1nrjA:
0.0		 2oaxF-1nrjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1og6 HYPOTHETICAL
OXIDOREDUCTASE YDHF

(Escherichia
coli) 		PF00248
(Aldo_ket_red) 		4 LEU A 167
LEU A 168
LEU A 126
MET A 134
 None
 1.14A 2oaxF-1og6A:
0.0		 2oaxF-1og6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvd PYRUVATE
DECARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A 540
LEU A 469
LEU A 440
MET A 370
 None
 1.09A 2oaxF-1pvdA:
0.0		 2oaxF-1pvdA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvd PYRUVATE
DECARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A 540
LEU A 469
LEU A 466
MET A 370
 None
 1.05A 2oaxF-1pvdA:
0.0		 2oaxF-1pvdA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1si8 CATALASE

(Enterococcus
faecalis) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 LEU A  88
LEU A 113
MET A 295
MET A 191
 None
 1.13A 2oaxF-1si8A:
0.0		 2oaxF-1si8A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ua2 CELL DIVISION
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 206
LEU A 269
MET A 118
MET A 292
 None
 1.00A 2oaxF-1ua2A:
undetectable		 2oaxF-1ua2A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uhg OVALBUMIN

(Gallus gallus) 		PF00079
(Serpin) 		4 LEU A 321
LEU A 312
LEU A  43
MET A 172
 DSN  A 320 ( 4.6A)
None
None
None
 1.11A 2oaxF-1uhgA:
undetectable		 2oaxF-1uhgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbf 231AA LONG
HYPOTHETICAL
PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF01135
(PCMT) 		4 LEU A 147
LEU A 148
LEU A 127
MET A 161
 None
 1.03A 2oaxF-1vbfA:
undetectable		 2oaxF-1vbfA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		4 LEU A 279
LEU A 282
LEU A 519
MET A 692
 None
 1.02A 2oaxF-1w27A:
undetectable		 2oaxF-1w27A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wh6 HOMEOBOX PROTEIN
CUX-2

(Homo sapiens) 		PF02376
(CUT) 		4 LEU A  47
LEU A  45
LEU A  78
MET A  55
 None
 1.10A 2oaxF-1wh6A:
undetectable		 2oaxF-1wh6A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8p DIHYDROLIPOYLLYSINE-
RESIDUE
ACETYLTRANSFERASE
COMPONENT OF
PYRUVATE
DEHYDROGENASE
COMPLEX

(Homo sapiens) 		PF00364
(Biotin_lipoyl) 		4 LEU B 200
LEU B 137
LEU B 166
MET B 144
 None
 0.90A 2oaxF-1y8pB:
undetectable		 2oaxF-1y8pB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		4 LEU A  70
LEU A  37
LEU A  57
MET A  20
 None
 1.13A 2oaxF-1yulA:
undetectable		 2oaxF-1yulA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 LEU B 173
LEU B 170
MET B   1
MET B 239
 None
 1.04A 2oaxF-2amcB:
undetectable		 2oaxF-2amcB:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayn UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14

(Homo sapiens) 		PF00443
(UCH) 		4 LEU A 155
LEU A 174
LEU A 109
MET A 206
 None
 1.07A 2oaxF-2aynA:
undetectable		 2oaxF-2aynA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ec1 NUCLEOPORIN 50 KDA

(Homo sapiens) 		PF00638
(Ran_BP1) 		4 LEU A  40
LEU A  38
LEU A  62
MET A 102
 None
 1.00A 2oaxF-2ec1A:
undetectable		 2oaxF-2ec1A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eij CYTOCHROME C OXIDASE
SUBUNIT 1

(Bos taurus) 		PF00115
(COX1) 		4 LEU A 199
LEU A 195
LEU A 248
MET A  74
 None
 1.01A 2oaxF-2eijA:
undetectable		 2oaxF-2eijA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fdr CONSERVED
HYPOTHETICAL PROTEIN

(Agrobacterium
fabrum) 		PF13419
(HAD_2) 		4 LEU A  82
LEU A  78
LEU A  29
MET A  42
 None
 1.04A 2oaxF-2fdrA:
undetectable		 2oaxF-2fdrA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0d B LYMPHOMA MO-MLV
INSERTION REGION
UBIQUITIN LIGASE
PROTEIN RING2

(Homo sapiens) 		PF13923
(zf-C3HC4_2) 		4 LEU A  12
LEU A  82
LEU B  45
MET B  50
 None
 1.09A 2oaxF-2h0dA:
undetectable		 2oaxF-2h0dA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hau SEROTRANSFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		4 LEU A 293
LEU A 294
LEU A 267
MET A  26
 None
 1.12A 2oaxF-2hauA:
undetectable		 2oaxF-2hauA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR

(Agrobacterium
fabrum) 		PF00126
(HTH_1) 		4 LEU A  32
LEU A  29
LEU A  22
MET A  46
 None
 1.07A 2oaxF-2ijlA:
undetectable		 2oaxF-2ijlA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgd 2-OXOGLUTARATE
DEHYDROGENASE E1
COMPONENT

(Escherichia
coli) 		PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 LEU A 316
LEU A 267
LEU A 213
MET A 258
 None
 1.14A 2oaxF-2jgdA:
undetectable		 2oaxF-2jgdA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9j HYPOTHETICAL PROTEIN
AQ2171

(Aquifex
aeolicus) 		PF08282
(Hydrolase_3) 		4 LEU A  20
LEU A 149
LEU A  47
MET A  14
 None
 1.14A 2oaxF-2p9jA:
undetectable		 2oaxF-2p9jA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE

(Medicago
truncatula) 		PF00201
(UDPGT) 		4 LEU A  25
LEU A  28
LEU A  34
MET A  13
 None
 1.04A 2oaxF-2pq6A:
undetectable		 2oaxF-2pq6A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uwj TYPE III EXPORT
PROTEIN PSCG

(Pseudomonas
aeruginosa) 		PF09477
(Type_III_YscG) 		4 LEU G  91
LEU G  87
LEU G  81
MET G 109
 None
 1.14A 2oaxF-2uwjG:
undetectable		 2oaxF-2uwjG:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vh1 CELL DIVISION
PROTEIN FTSQ

(Escherichia
coli) 		PF03799
(FtsQ)
PF08478
(POTRA_1) 		4 LEU A 181
LEU A 188
LEU A 171
MET A 193
 None
 0.90A 2oaxF-2vh1A:
undetectable		 2oaxF-2vh1A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w21 GLUTAMATE 5-KINASE

(Escherichia
coli) 		PF00696
(AA_kinase) 		4 LEU A 124
LEU A 121
LEU A 115
MET A 101
 None
 0.98A 2oaxF-2w21A:
undetectable		 2oaxF-2w21A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wkw CARBOXYLESTERASE

(Alcaligenes sp.) 		no annotation 4 LEU A 203
LEU A  67
LEU A  93
MET A  86
 None
 1.13A 2oaxF-2wkwA:
undetectable		 2oaxF-2wkwA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE

(Staphylococcus
aureus) 		PF00155
(Aminotran_1_2) 		4 LEU A 106
LEU A 100
LEU A  94
MET A 111
 None
 0.97A 2oaxF-2x5fA:
undetectable		 2oaxF-2x5fA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwa LEUCINE CARBOXYL
METHYLTRANSFERASE 2

(Saccharomyces
cerevisiae) 		PF04072
(LCM)
PF13418
(Kelch_4) 		4 LEU A 227
LEU A 114
LEU A 206
MET A 245
 None
 1.10A 2oaxF-2zwaA:
undetectable		 2oaxF-2zwaA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a98 DEDICATOR OF
CYTOKINESIS PROTEIN
2
ENGULFMENT AND CELL
MOTILITY PROTEIN 1

(Homo sapiens) 		PF07653
(SH3_2)
PF16172
(DOCK_N)
PF16457
(PH_12) 		4 LEU B 699
LEU B 696
LEU B 690
MET A 125
 None
 0.85A 2oaxF-3a98B:
undetectable		 2oaxF-3a98B:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf8 ESTERASE YBFF

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		4 LEU A 163
LEU A 162
LEU A 178
MET A 149
 None
 1.02A 2oaxF-3bf8A:
undetectable		 2oaxF-3bf8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwc METALLOCARBOXYPEPTID
ASE

(Trypanosoma
cruzi) 		PF02074
(Peptidase_M32) 		4 LEU A 127
LEU A 130
LEU A 136
MET A 371
 None
 1.11A 2oaxF-3dwcA:
undetectable		 2oaxF-3dwcA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5d PUTATIVE GLYOXALASE
I

(Listeria
monocytogenes) 		PF00903
(Glyoxalase) 		4 LEU A  87
LEU A  91
LEU A 115
MET A  16
 None
 0.94A 2oaxF-3e5dA:
undetectable		 2oaxF-3e5dA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE

(Mycobacterium
tuberculosis) 		PF00268
(Ribonuc_red_sm) 		4 LEU A 143
LEU A 139
LEU A 237
MET A 169
 None
 0.75A 2oaxF-3ee4A:
3.0		 2oaxF-3ee4A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr2 HEXULOSE-6-PHOSPHATE
SYNTHASE SGBH

(Vibrio cholerae) 		PF00215
(OMPdecase) 		4 LEU A 162
LEU A 159
LEU A 153
MET A 119
 None
 0.92A 2oaxF-3jr2A:
undetectable		 2oaxF-3jr2A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1i PUTATIVE
UNCHARACTERIZED
PROTEIN

(Helicobacter
pylori) 		PF16522
(FliS_cochap) 		4 LEU C  47
LEU C  50
LEU C 128
MET C 109
 None
 1.13A 2oaxF-3k1iC:
undetectable		 2oaxF-3k1iC:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lhx KETODEOXYGLUCONOKINA
SE

(Shigella
flexneri) 		PF00294
(PfkB) 		4 LEU A 211
LEU A 206
LEU A 198
MET A 260
 None
 1.05A 2oaxF-3lhxA:
undetectable		 2oaxF-3lhxA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lot UNCHARACTERIZED
PROTEIN

(Archaeoglobus
fulgidus) 		PF05853
(BKACE) 		4 LEU A 305
LEU A 303
LEU A 198
MET A  47
 None
 1.12A 2oaxF-3lotA:
undetectable		 2oaxF-3lotA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oox PUTATIVE 2OG-FE(II)
OXYGENASE FAMILY
PROTEIN

(Caulobacter
vibrioides) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		4 LEU A 226
LEU A  37
LEU A  13
MET A 140
 None
 1.13A 2oaxF-3ooxA:
undetectable		 2oaxF-3ooxA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opb SWI5-DEPENDENT HO
EXPRESSION PROTEIN 4

(Saccharomyces
cerevisiae) 		PF11701
(UNC45-central) 		4 LEU A 657
LEU A 654
LEU A 648
MET A 610
 None
 1.08A 2oaxF-3opbA:
undetectable		 2oaxF-3opbA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfr MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Actinobacillus
succinogenes) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 235
LEU A 207
LEU A  26
MET A 184
 None
 1.12A 2oaxF-3pfrA:
undetectable		 2oaxF-3pfrA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps9 TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC

(Escherichia
coli) 		PF01266
(DAO)
PF05430
(Methyltransf_30) 		4 LEU A 630
LEU A 279
LEU A 292
MET A 634
 None
 1.12A 2oaxF-3ps9A:
undetectable		 2oaxF-3ps9A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qit POLYKETIDE SYNTHASE

(Moorea
producens) 		PF00561
(Abhydrolase_1) 		4 LEU A 233
LEU A 122
LEU A 105
MET A 254
 None
 1.10A 2oaxF-3qitA:
undetectable		 2oaxF-3qitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyy RESPONSE REGULATOR

(Xanthomonas
campestris) 		PF00990
(GGDEF) 		4 LEU A 196
LEU A 193
LEU A 187
MET A 174
 None
 0.98A 2oaxF-3qyyA:
undetectable		 2oaxF-3qyyA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF05214
(Baculo_p33) 		4 LEU A 212
LEU A 216
LEU A 118
MET A 142
 None
 0.92A 2oaxF-3qzyA:
undetectable		 2oaxF-3qzyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sto SERINE PROTEASE
INHIBITOR

(Schistosoma
haematobium) 		PF00079
(Serpin) 		4 LEU A 335
LEU A 326
LEU A  54
MET A 186
 None
 1.13A 2oaxF-3stoA:
undetectable		 2oaxF-3stoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swg UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Aquifex
aeolicus) 		PF00275
(EPSP_synthase) 		4 LEU A  66
LEU A  63
LEU A  57
MET A  38
 None
EDO  A 511 ( 4.4A)
None
None
 1.03A 2oaxF-3swgA:
undetectable		 2oaxF-3swgA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tkn NUCLEOPORIN NUP82

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 216
LEU A 212
LEU A 194
MET A 333
 None
 1.08A 2oaxF-3tknA:
undetectable		 2oaxF-3tknA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v7i PUTATIVE POLYKETIDE
SYNTHASE

(Streptomyces
coelicolor) 		PF00195
(Chal_sti_synt_N) 		4 LEU A 335
LEU A 309
LEU A 372
MET A 322
 None
 1.13A 2oaxF-3v7iA:
undetectable		 2oaxF-3v7iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glk ABIQ

(Lactococcus
lactis) 		PF13958
(ToxN_toxin) 		4 LEU A  87
LEU A  50
LEU A 103
MET A 122
 None
 1.05A 2oaxF-4glkA:
undetectable		 2oaxF-4glkA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb4 EXPORTIN-1

(Saccharomyces
cerevisiae) 		PF03810
(IBN_N)
PF08389
(Xpo1)
PF08767
(CRM1_C) 		4 LEU C 297
LEU C 312
MET C 291
MET C 243
 None
 0.99A 2oaxF-4hb4C:
undetectable		 2oaxF-4hb4C:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iau BETA-GAMMA-CRYSTALLI
N

(Geodia cydonium) 		PF00030
(Crystall) 		4 LEU A 156
LEU A  88
LEU A 117
MET A 159
 None
 1.08A 2oaxF-4iauA:
undetectable		 2oaxF-4iauA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jza UNCHARACTERIZED
PROTEIN

(Legionella
longbeachae) 		no annotation 4 LEU A 277
LEU A 281
LEU A 226
MET A 267
 None
 1.06A 2oaxF-4jzaA:
undetectable		 2oaxF-4jzaA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k37 ANAEROBIC
SULFATASE-MATURATING
ENZYME

(Clostridium
perfringens) 		PF04055
(Radical_SAM)
PF13186
(SPASM)
PF13353
(Fer4_12) 		4 LEU A   4
LEU A   6
LEU A  44
MET A 294
 None
 0.96A 2oaxF-4k37A:
undetectable		 2oaxF-4k37A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k90 EXTRACELLULAR
METALLOPROTEINASE
MEP

(Aspergillus
fumigatus) 		PF02128
(Peptidase_M36) 		4 LEU A 353
LEU A 356
LEU A 594
MET A 465
 None
 1.11A 2oaxF-4k90A:
undetectable		 2oaxF-4k90A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf7 NUP188

(Thermothelomyces
thermophila) 		PF10487
(Nup188) 		4 LEU A 555
LEU A 551
LEU A 533
MET A 582
 None
 1.01A 2oaxF-4kf7A:
undetectable		 2oaxF-4kf7A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l22 PHOSPHORYLASE

(Streptococcus
mutans) 		PF00343
(Phosphorylase) 		4 LEU A 339
LEU A 332
LEU A 238
MET A 284
 None
 1.07A 2oaxF-4l22A:
undetectable		 2oaxF-4l22A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m6t RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1

(Homo sapiens) 		PF03985
(Paf1)
PF04004
(Leo1) 		4 LEU A 108
LEU A  95
LEU A 103
MET A  45
 None
 0.99A 2oaxF-4m6tA:
undetectable		 2oaxF-4m6tA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mxm TRANSCRIPTIONAL
REGULATOR I2

(Pseudomonas
fluorescens) 		PF00440
(TetR_N) 		4 LEU A 195
LEU A 191
LEU A 100
MET A  78
 None
 1.11A 2oaxF-4mxmA:
undetectable		 2oaxF-4mxmA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nj5 PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH9

(Arabidopsis
thaliana) 		PF00856
(SET)
PF02182
(SAD_SRA)
PF05033
(Pre-SET) 		4 LEU A 222
LEU A 227
LEU A 328
MET A 359
 None
 1.12A 2oaxF-4nj5A:
undetectable		 2oaxF-4nj5A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9a POLYMERASE PA

(Influenza A
virus) 		PF00603
(Flu_PA) 		4 LEU A 345
LEU A 342
LEU A 543
MET A 311
 None
 0.94A 2oaxF-4p9aA:
undetectable		 2oaxF-4p9aA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdh VARIABLE LYMPHOCYTE
RECEPTOR B,
TOLL-LIKE RECEPTOR 9
CHIMERA

(Eptatretus
burgeri;
Mus musculus) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13306
(LRR_5)
PF13855
(LRR_8) 		4 LEU A 256
LEU A 228
LEU A 201
MET A 190
 None
 1.06A 2oaxF-4qdhA:
undetectable		 2oaxF-4qdhA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qj4 1-PHOSPHATIDYLINOSIT
OL 4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 LEU B 788
LEU B 791
LEU B 663
MET B 705
 None
 1.07A 2oaxF-4qj4B:
undetectable		 2oaxF-4qj4B:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9l LIMONENE-1,2-EPOXIDE
HYDROLASE

(Rhodococcus
erythropolis) 		PF07858
(LEH) 		4 LEU A 103
LEU A 114
LEU A 117
MET A  56
 HYH  A 201 ( 4.5A)
None
None
None
 1.08A 2oaxF-4r9lA:
undetectable		 2oaxF-4r9lA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udj UHGB_MP

(uncultured
organism) 		PF04041
(Glyco_hydro_130) 		4 LEU A 249
LEU A 228
LEU A 265
MET A 198
 None
 1.09A 2oaxF-4udjA:
undetectable		 2oaxF-4udjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhg SIMILAR TO
UNIPROT|P29295
SACCHAROMYCES
CEREVISIAE YPL204W
HRR25

([Candida]
glabrata) 		PF00069
(Pkinase) 		4 LEU A  89
LEU A  92
LEU A 293
MET A 136
 None
 1.12A 2oaxF-4xhgA:
undetectable		 2oaxF-4xhgA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhl CASEIN KINASE I
HOMOLOG HRR25

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		4 LEU A  89
LEU A  92
LEU A 293
MET A 136
 None
 1.11A 2oaxF-4xhlA:
undetectable		 2oaxF-4xhlA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxo GLYCOSYL HYDROLASE
FAMILY 26

(Bacteroides
ovatus) 		PF02156
(Glyco_hydro_26) 		4 LEU A  37
LEU A  41
LEU A 254
MET A 119
 None
 1.08A 2oaxF-4zxoA:
undetectable		 2oaxF-4zxoA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzy POLY [ADP-RIBOSE]
POLYMERASE 2

(Homo sapiens) 		PF00644
(PARP)
PF02877
(PARP_reg) 		4 LEU A 372
LEU A 404
LEU A 484
MET A 569
 None
 1.03A 2oaxF-4zzyA:
undetectable		 2oaxF-4zzyA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aqa OFF7_DB04V3

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13354
(Beta-lactamase2) 		4 LEU A 337
LEU A 324
LEU A 179
MET A 341
 None
 1.12A 2oaxF-5aqaA:
undetectable		 2oaxF-5aqaA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqr 7-HYDROXYMETHYL
CHLOROPHYLL A
REDUCTASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF04422
(FrhB_FdhB_N)
PF04432
(FrhB_FdhB_C) 		4 LEU A 231
LEU A 205
LEU A 225
MET A 344
 None
 1.06A 2oaxF-5dqrA:
undetectable		 2oaxF-5dqrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5efn HDAC6 PROTEIN

(Danio rerio) 		no annotation 4 LEU B 732
LEU B 729
MET B 687
MET B 679
 None
 0.75A 2oaxF-5efnB:
undetectable		 2oaxF-5efnB:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g0h HDAC6

(Danio rerio) 		PF00850
(Hist_deacetyl) 		4 LEU A 732
LEU A 729
MET A 687
MET A 679
 None
 0.76A 2oaxF-5g0hA:
undetectable		 2oaxF-5g0hA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjq UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14

(Homo sapiens) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		4 LEU x 155
LEU x 174
LEU x 109
MET x 206
 None
 1.11A 2oaxF-5gjqx:
undetectable		 2oaxF-5gjqx:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i67 PHOSPHOENOLPYRUVATE
CARBOXYKINASE [GTP]

(Mycobacterium
tuberculosis) 		PF00821
(PEPCK_C)
PF17297
(PEPCK_N) 		4 LEU A  19
LEU A 226
MET A 170
MET A 132
 None
 1.12A 2oaxF-5i67A:
undetectable		 2oaxF-5i67A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inf CARBOXYL TRANSFERASE

(Streptomyces
ambofaciens) 		PF01039
(Carboxyl_trans) 		4 LEU A 398
LEU A 349
LEU A 345
MET A 425
 None
 1.12A 2oaxF-5infA:
undetectable		 2oaxF-5infA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jju UNCHARACTERIZED
PROTEIN RV2837C

(Mycobacterium
tuberculosis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 LEU A 116
LEU A 119
LEU A 101
MET A  95
 None
 0.96A 2oaxF-5jjuA:
undetectable		 2oaxF-5jjuA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k04 UNCHARACTERIZED
PROTEIN

(Candida
albicans) 		PF09797
(NatB_MDM20) 		4 LEU A 608
LEU A 611
LEU A 631
MET A 683
 None
 1.00A 2oaxF-5k04A:
undetectable		 2oaxF-5k04A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mu5 UNCHARACTERIZED
PROTEIN

(Magnetospirillum
magneticum) 		no annotation 4 LEU A 579
LEU A 580
LEU A 178
MET A 599
 None
 1.11A 2oaxF-5mu5A:
undetectable		 2oaxF-5mu5A:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mwp MINERALOCORTICOID
RECEPTOR

(Homo sapiens) 		no annotation 4 LEU A 766
LEU A 769
MET A 845
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 0.77A 2oaxF-5mwpA:
37.8		 2oaxF-5mwpA:
73.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol0 PUTATIVE SILENT
INFORMATION
REGULATOR 2,PUTATIVE
SILENT INFORMATION
REGULATOR 2

(Leishmania
infantum) 		no annotation 4 LEU A  19
LEU A 342
LEU A 111
MET A 240
 None
 1.14A 2oaxF-5ol0A:
undetectable		 2oaxF-5ol0A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT B

(Methanothermobacter
sp. CaT2) 		PF00384
(Molybdopterin) 		4 LEU B 103
LEU B 418
LEU B 412
MET B 339
 None
 0.99A 2oaxF-5t5iB:
undetectable		 2oaxF-5t5iB:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tmh POLYPROTEIN

(Zika virus) 		PF00972
(Flavi_NS5)
PF01728
(FtsJ) 		4 LEU A 617
LEU A 382
LEU A 553
MET A 499
 None
 1.00A 2oaxF-5tmhA:
undetectable		 2oaxF-5tmhA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u04 ZIKA VIRUS NS5 RDRP

(Zika virus) 		PF00972
(Flavi_NS5) 		4 LEU A 617
LEU A 382
LEU A 553
MET A 499
 None
 0.95A 2oaxF-5u04A:
undetectable		 2oaxF-5u04A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5van BETA-KLOTHO

(Homo sapiens) 		no annotation 4 LEU A 327
LEU A 300
LEU A 273
MET A 363
 None
 1.10A 2oaxF-5vanA:
undetectable		 2oaxF-5vanA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve3 BPPRF

(Paraburkholderia
phytofirmans) 		no annotation 4 LEU B   2
LEU B  19
LEU B   7
MET B 128
 None
 1.05A 2oaxF-5ve3B:
undetectable		 2oaxF-5ve3B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wi9 -

(-) 		no annotation 4 LEU A 327
LEU A 300
LEU A 273
MET A 363
 None
 1.11A 2oaxF-5wi9A:
undetectable		 2oaxF-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7l TSRD

(Streptomyces
laurentii) 		no annotation 4 LEU A  63
LEU A  14
LEU A   9
MET A  79
 IPA  A 201 ( 4.5A)
None
None
None
 1.05A 2oaxF-5x7lA:
undetectable		 2oaxF-5x7lA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xto FAD-LINKED
SULFHYDRYL OXIDASE

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF05214
(Baculo_p33) 		4 LEU A 212
LEU A 216
LEU A 118
MET A 142
 None
 1.08A 2oaxF-5xtoA:
undetectable		 2oaxF-5xtoA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 LEU A 677
LEU A 649
LEU A 622
MET A 611
 None
 1.03A 2oaxF-5zlnA:
undetectable		 2oaxF-5zlnA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9h PROTEIN HOOK HOMOLOG
3

(Homo sapiens) 		no annotation 4 LEU A 119
LEU A 115
LEU A 105
MET A  41
 None
 1.01A 2oaxF-6b9hA:
undetectable		 2oaxF-6b9hA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN

(Influenza A
virus;
Saccharomyces
cerevisiae) 		no annotation 4 LEU A 345
LEU A 342
LEU A 543
MET A 311
 EZS  A 801 (-3.6A)
EZS  A 801 (-4.2A)
None
None
 0.91A 2oaxF-6cfpA:
undetectable		 2oaxF-6cfpA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6co7 PREDICTED PROTEIN

(Nematostella
vectensis) 		no annotation 4 LEU A 616
LEU A 589
LEU A 491
MET A 519
 None
 1.11A 2oaxF-6co7A:
undetectable		 2oaxF-6co7A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME COMPLEX
EXONUCLEASE RRP44

(Homo sapiens) 		no annotation 4 LEU K 616
LEU K 620
LEU K 668
MET K 566
 None
 0.93A 2oaxF-6d6qK:
undetectable		 2oaxF-6d6qK:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6em0 2-HYDROXYBIPHENYL-3-
MONOOXYGENASE

(Pseudomonas
nitroreducens) 		no annotation 4 LEU A  70
LEU A 118
MET A 126
MET A  20
 None
 1.13A 2oaxF-6em0A:
undetectable		 2oaxF-6em0A:
18.40