SIMILAR PATTERNS OF AMINO ACIDS FOR 2OAX_A_SNLA1001_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5l UREASE (ALPHA
SUBUNIT)

(Klebsiella
aerogenes) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 LEU C 147
ALA C 143
TRP C 137
LEU C 187
 None
 1.13A 2oaxA-1a5lC:
0.0		 2oaxA-1a5lC:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		4 LEU A  37
ALA A  40
LEU A  69
MET A 250
 None
 1.25A 2oaxA-1g8pA:
undetectable		 2oaxA-1g8pA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq1 CYTOCHROME CD1
NITRITE REDUCTASE

(Paracoccus
pantotrophus) 		PF02239
(Cytochrom_D1)
PF13442
(Cytochrome_CBB3) 		4 LEU A 344
ALA A 359
TRP A 404
LEU A 366
 None
 1.23A 2oaxA-1gq1A:
undetectable		 2oaxA-1gq1A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gsq GLUTATHIONE
S-TRANSFERASE

(Todarodes
pacificus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 LEU A  21
ALA A  23
LEU A 154
MET A  64
 None
 1.02A 2oaxA-1gsqA:
undetectable		 2oaxA-1gsqA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5x XANTHINE
DEHYDROGENASE

(Bos taurus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 LEU A 494
ALA A 491
LEU A 513
MET A 438
 None
 1.24A 2oaxA-1n5xA:
undetectable		 2oaxA-1n5xA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pcg ESTROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 346
ALA A 350
TRP A 383
LEU A 387
 EST  A   1 (-4.4A)
EST  A   1 ( 3.7A)
None
EST  A   1 (-4.0A)
 0.50A 2oaxA-1pcgA:
26.7		 2oaxA-1pcgA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ppr PERIDININ-CHLOROPHYL
L PROTEIN

(Amphidinium
carterae) 		PF02429
(PCP) 		4 LEU M  58
ALA M  91
LEU M  92
MET M  50
 None
None
PID  M 614 (-4.5A)
PID  M 613 ( 4.0A)
 1.25A 2oaxA-1pprM:
0.9		 2oaxA-1pprM:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r76 PECTATE LYASE

(Niveispirillum
irakense) 		PF09492
(Pec_lyase) 		4 LEU A 202
ALA A 200
TRP A 124
LEU A 182
 None
 1.04A 2oaxA-1r76A:
undetectable		 2oaxA-1r76A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrz GLYCOGEN SYNTHESIS
PROTEIN GLGS

(Escherichia
coli) 		PF08971
(GlgS) 		4 LEU A  14
ALA A  32
LEU A  31
MET A  56
 None
 1.21A 2oaxA-1rrzA:
undetectable		 2oaxA-1rrzA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rt8 FIMBRIN

(Schizosaccharomyces
pombe) 		PF00307
(CH) 		4 LEU A 339
ALA A 354
TRP A 226
LEU A 353
 None
 1.05A 2oaxA-1rt8A:
undetectable		 2oaxA-1rt8A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES

(Salmonella
enterica) 		PF02613
(Nitrate_red_del) 		4 LEU A 131
ALA A 135
TRP A 189
LEU A 151
 None
 0.97A 2oaxA-1s9uA:
undetectable		 2oaxA-1s9uA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tl2 PROTEIN
(TACHYLECTIN-2)

(Tachypleus
tridentatus) 		PF14517
(Tachylectin) 		4 LEU A 109
ALA A 103
TRP A 122
LEU A 101
 None
 1.06A 2oaxA-1tl2A:
undetectable		 2oaxA-1tl2A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wxx HYPOTHETICAL PROTEIN
TTHA1280

(Thermus
thermophilus) 		PF10672
(Methyltrans_SAM) 		4 LEU A 315
ALA A 311
LEU A 285
MET A 205
 None
 1.22A 2oaxA-1wxxA:
undetectable		 2oaxA-1wxxA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yts YERSINIA PROTEIN
TYROSINE PHOSPHATASE

(Yersinia
enterocolitica) 		PF00102
(Y_phosphatase) 		4 LEU A 282
ALA A 283
LEU A 285
MET A 298
 None
 1.16A 2oaxA-1ytsA:
undetectable		 2oaxA-1ytsA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zyl HYPOTHETICAL PROTEIN
YIHE

(Escherichia
coli) 		PF01636
(APH) 		4 LEU A 159
ALA A 163
TRP A 303
LEU A 165
 None
 1.25A 2oaxA-1zylA:
undetectable		 2oaxA-1zylA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfm THERMOSTABLE DNA
LIGASE

(Pyrococcus
furiosus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 LEU A 300
ALA A 253
LEU A 316
MET A 328
 None
 1.09A 2oaxA-2cfmA:
undetectable		 2oaxA-2cfmA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfo GLUTAMYL-TRNA
SYNTHETASE

(Synechococcus
elongatus) 		PF00749
(tRNA-synt_1c) 		4 LEU A 294
ALA A 296
TRP A  27
LEU A  28
 None
 1.25A 2oaxA-2cfoA:
undetectable		 2oaxA-2cfoA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f37 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2

(Homo sapiens) 		PF12796
(Ank_2) 		4 LEU A 238
ALA A 236
LEU A 228
MET A 269
 None
 1.17A 2oaxA-2f37A:
undetectable		 2oaxA-2f37A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fji EXOCYST COMPLEX
COMPONENT SEC6

(Saccharomyces
cerevisiae) 		PF06046
(Sec6) 		4 LEU 1 776
ALA 1 772
LEU 1 750
MET 1 795
 None
 1.09A 2oaxA-2fji1:
undetectable		 2oaxA-2fji1:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gpv ESTROGEN-RELATED
RECEPTOR GAMMA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 268
ALA A 272
TRP A 305
LEU A 309
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
None
OHT  A 500 ( 4.0A)
 0.71A 2oaxA-2gpvA:
26.0		 2oaxA-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j86 PROTEIN
SERINE-THREONINE
PHOSPHATASE

(Synechococcus
elongatus) 		PF13672
(PP2C_2) 		4 LEU A  48
ALA A  79
LEU A 167
MET A  36
 None
 1.06A 2oaxA-2j86A:
undetectable		 2oaxA-2j86A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jk9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 1

(Homo sapiens) 		PF00622
(SPRY) 		4 LEU A 178
ALA A 180
LEU A  97
MET A  43
 None
 1.10A 2oaxA-2jk9A:
undetectable		 2oaxA-2jk9A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lgy RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1

(Homo sapiens) 		no annotation 4 LEU A  79
ALA A  77
LEU A   8
MET A  38
 None
 1.13A 2oaxA-2lgyA:
undetectable		 2oaxA-2lgyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocf ESTROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 346
ALA A 350
TRP A 383
LEU A 387
 EST  A 596 (-4.4A)
EST  A 596 ( 3.9A)
None
EST  A 596 ( 4.2A)
 0.51A 2oaxA-2ocfA:
27.9		 2oaxA-2ocfA:
28.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4q 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING 1

(Saccharomyces
cerevisiae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 LEU A 195
ALA A 199
TRP A 221
LEU A 322
 None
 1.23A 2oaxA-2p4qA:
undetectable		 2oaxA-2p4qA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Roseovarius
nubinhibens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 125
ALA A 309
LEU A 305
MET A 107
 None
 1.22A 2oaxA-2qddA:
undetectable		 2oaxA-2qddA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN

(Salmonella
enterica) 		PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA) 		4 LEU A 689
ALA A 692
TRP A 781
LEU A 777
 None
 1.11A 2oaxA-2qzaA:
undetectable		 2oaxA-2qzaA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9l PUTATIVE DNA
LIGASE-LIKE PROTEIN

(Mycobacterium
tuberculosis) 		no annotation 4 LEU A 149
ALA A 153
TRP A 257
LEU A 179
 None
 1.17A 2oaxA-2r9lA:
undetectable		 2oaxA-2r9lA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3chi P-AMINOBENZOATE
N-OXYGENASE

(Streptomyces
thioluteus) 		PF11583
(AurF) 		4 LEU A 206
ALA A 204
LEU A 224
MET A 142
 None
 1.21A 2oaxA-3chiA:
2.2		 2oaxA-3chiA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ek1 ALDEHYDE
DEHYDROGENASE

(Brucella
abortus) 		PF00171
(Aldedh) 		4 LEU A 188
ALA A 192
LEU A   9
MET A   1
 None
 0.87A 2oaxA-3ek1A:
undetectable		 2oaxA-3ek1A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emy TRICHODERMA REESEI
ASPARTIC PROTEASE

(Trichoderma
reesei) 		PF00026
(Asp) 		4 LEU A 272
ALA A 306
TRP A 323
LEU A 307
 None
 1.22A 2oaxA-3emyA:
undetectable		 2oaxA-3emyA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gt5 N-ACETYLGLUCOSAMINE
2-EPIMERASE

(Xylella
fastidiosa) 		PF07221
(GlcNAc_2-epim) 		4 LEU A  88
ALA A 140
LEU A 133
MET A  70
 None
 1.26A 2oaxA-3gt5A:
undetectable		 2oaxA-3gt5A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i16 ALUMINUM RESISTANCE
PROTEIN

(Clostridium
novyi) 		PF06838
(Met_gamma_lyase) 		4 LEU A 236
ALA A 238
LEU A 103
MET A 117
 None
 1.19A 2oaxA-3i16A:
undetectable		 2oaxA-3i16A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6b 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE

(Escherichia
coli) 		PF08282
(Hydrolase_3) 		4 LEU A  29
ALA A  65
LEU A 174
MET A  20
 None
 0.98A 2oaxA-3i6bA:
undetectable		 2oaxA-3i6bA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iiu PERIDININ-CHLOROPHYL
L A-BINDING PROTEIN
1, CHLOROPLASTIC

(Amphidinium
carterae) 		PF02429
(PCP) 		4 LEU M  58
ALA M  91
LEU M  92
MET M  50
 None
None
CLA  M 601 ( 4.3A)
PID  M 613 ( 3.8A)
 1.25A 2oaxA-3iiuM:
undetectable		 2oaxA-3iiuM:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd4 PUTATIVE PROTEASE

(Parabacteroides
distasonis) 		PF12969
(DUF3857)
PF12970
(DUF3858) 		4 LEU A 149
ALA A 226
TRP A 200
LEU A 224
 GOL  A   7 (-4.2A)
None
None
None
 1.23A 2oaxA-3kd4A:
undetectable		 2oaxA-3kd4A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kih 5-BLADED
BETA-PROPELLER
LECTIN

(synthetic
construct) 		PF14517
(Tachylectin) 		4 LEU A  73
ALA A  67
TRP A  86
LEU A  65
 None
 1.01A 2oaxA-3kihA:
undetectable		 2oaxA-3kihA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l76 ASPARTOKINASE

(Synechocystis
sp. PCC 6803) 		PF00696
(AA_kinase)
PF01842
(ACT)
PF13840
(ACT_7) 		4 LEU A 590
ALA A 191
LEU A 181
MET A 202
 None
 0.93A 2oaxA-3l76A:
undetectable		 2oaxA-3l76A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvg CLATHRIN HEAVY CHAIN
1

(Bos taurus) 		PF00637
(Clathrin) 		4 LEU A1533
ALA A1537
TRP A1556
LEU A1527
 None
 1.03A 2oaxA-3lvgA:
undetectable		 2oaxA-3lvgA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qld MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 280
ALA A 282
LEU A 273
MET A 112
 None
 1.23A 2oaxA-3qldA:
undetectable		 2oaxA-3qldA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3quc INORGANIC
PYROPHOSPHATASE

(Bacteroides
thetaiotaomicron) 		PF13419
(HAD_2) 		4 LEU A   9
TRP A 219
LEU A 107
MET A 131
 None
 1.20A 2oaxA-3qucA:
undetectable		 2oaxA-3qucA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyq DEOXYRIBOSE-PHOSPHAT
E ALDOLASE, PUTATIVE

(Toxoplasma
gondii) 		no annotation 4 LEU A 190
ALA A 161
LEU A 172
MET A 242
 None
 1.08A 2oaxA-3qyqA:
undetectable		 2oaxA-3qyqA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rwk INULINASE

(Aspergillus
ficuum) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 LEU X 122
ALA X 140
TRP X  72
MET X 190
 None
 1.09A 2oaxA-3rwkX:
undetectable		 2oaxA-3rwkX:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tot GLUTATHIONE
S-TRANSFERASE
PROTEIN

(Ralstonia
solanacearum) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 LEU A 137
ALA A 139
TRP A  95
LEU A  98
 None
 1.13A 2oaxA-3totA:
undetectable		 2oaxA-3totA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsm INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE

(Brucella
abortus) 		PF00218
(IGPS) 		4 LEU A 209
ALA A 213
LEU A 182
MET A 146
 None
 0.92A 2oaxA-3tsmA:
undetectable		 2oaxA-3tsmA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u41 TWIN-ARGININE
LEADER-BINDING
PROTEIN DMSD

(Escherichia
coli) 		PF02613
(Nitrate_red_del) 		4 LEU A 131
ALA A 135
TRP A 189
LEU A 151
 None
 1.25A 2oaxA-3u41A:
undetectable		 2oaxA-3u41A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A

(Bacillus
subtilis) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		4 LEU A 809
ALA A 807
TRP A 594
LEU A 589
 None
 1.14A 2oaxA-3u44A:
undetectable		 2oaxA-3u44A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3unv ADMH

(Pantoea
agglomerans) 		PF00221
(Lyase_aromatic) 		4 LEU A  37
ALA A  41
LEU A 231
MET A 378
 None
 0.68A 2oaxA-3unvA:
undetectable		 2oaxA-3unvA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdn MONOAMINE OXIDASE N

(Aspergillus
niger) 		PF01593
(Amino_oxidase) 		4 LEU A 363
ALA A 366
TRP A 353
LEU A 379
 None
 1.25A 2oaxA-3zdnA:
undetectable		 2oaxA-3zdnA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4axn CHITINASE C1

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18) 		4 LEU A 243
ALA A 251
LEU A 190
MET A 176
 None
 1.25A 2oaxA-4axnA:
undetectable		 2oaxA-4axnA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE

(Escherichia
coli) 		PF08007
(Cupin_4) 		4 LEU A 312
ALA A 320
TRP A 369
LEU A 309
 None
 0.86A 2oaxA-4cclA:
undetectable		 2oaxA-4cclA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccy CARBOXYLESTERASE
YBFK

(Bacillus
subtilis) 		PF12697
(Abhydrolase_6) 		4 LEU B  61
ALA B 127
TRP B  78
LEU B  58
 None
 0.99A 2oaxA-4ccyB:
undetectable		 2oaxA-4ccyB:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cit VANADIUM-DEPENDENT
HALOPEROXIDASE

(Zobellia
galactanivorans) 		PF01569
(PAP2) 		4 LEU A 149
ALA A 152
LEU A 111
MET A 122
 None
 1.26A 2oaxA-4citA:
2.5		 2oaxA-4citA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dbg RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1

(Homo sapiens) 		no annotation 4 LEU A 128
ALA A 126
LEU A  57
MET A  87
 None
 1.13A 2oaxA-4dbgA:
undetectable		 2oaxA-4dbgA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddw REVERSE GYRASE

(Thermotoga
maritima) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 LEU A 457
ALA A 398
LEU A 403
MET A 444
 None
 1.25A 2oaxA-4ddwA:
undetectable		 2oaxA-4ddwA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 LEU A 169
ALA A 165
LEU A 166
MET A 229
 None
 1.15A 2oaxA-4dxyA:
2.0		 2oaxA-4dxyA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exn INTERLEUKIN-34

(Mus musculus) 		PF15036
(IL34) 		4 LEU A  37
TRP A  94
LEU A 126
MET A 134
 None
 1.05A 2oaxA-4exnA:
undetectable		 2oaxA-4exnA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hr6 LECTIN

(Trichosanthes
anguina) 		PF00161
(RIP) 		4 LEU B 117
ALA B 121
LEU B 152
MET B 160
 None
 1.22A 2oaxA-4hr6B:
undetectable		 2oaxA-4hr6B:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC

(Solanum
lycopersicum) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 LEU A 463
ALA A 468
LEU A 542
MET A 497
 None
 1.22A 2oaxA-4ksiA:
undetectable		 2oaxA-4ksiA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		4 LEU A 143
ALA A 145
TRP A 127
LEU A 513
 None
 1.20A 2oaxA-4lglA:
undetectable		 2oaxA-4lglA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mk3 GLUTATHIONE
S-TRANSFERASE

(Cupriavidus
metallidurans) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 LEU A 135
ALA A 137
TRP A  93
LEU A  96
 None
PG4  A 303 (-3.6A)
PG4  A 303 (-2.9A)
PG4  A 303 ( 4.1A)
 1.12A 2oaxA-4mk3A:
undetectable		 2oaxA-4mk3A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n1y ESTROGEN RECEPTOR

(Crassostrea
gigas) 		PF00104
(Hormone_recep) 		4 LEU A 283
ALA A 287
TRP A 320
LEU A 324
 None
 0.57A 2oaxA-4n1yA:
28.1		 2oaxA-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n77 UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		PF09704
(Cas_Cas5d) 		4 LEU A 140
ALA A  42
LEU A  38
MET A  59
 None
 1.23A 2oaxA-4n77A:
undetectable		 2oaxA-4n77A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nv2 VKORC1/THIOREDOXIN
DOMAIN PROTEIN

(Synechococcus
sp.
JA-2-3B'a(2-13)) 		PF07884
(VKOR) 		4 LEU A  33
ALA A  35
LEU A  77
MET A 111
 None
None
None
U10  A 501 ( 4.6A)
 1.15A 2oaxA-4nv2A:
undetectable		 2oaxA-4nv2A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ony EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 5

(Brucella
melitensis) 		PF00496
(SBP_bac_5) 		4 LEU A 547
ALA A 530
LEU A 375
MET A 388
 None
 1.23A 2oaxA-4onyA:
undetectable		 2oaxA-4onyA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxq D-GLUCURONYL C5
EPIMERASE B

(Danio rerio) 		PF06662
(C5-epim_C) 		4 LEU A 439
ALA A 437
TRP A 390
LEU A 422
 None
 1.23A 2oaxA-4pxqA:
undetectable		 2oaxA-4pxqA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q88 UNCHARACTERIZED
PROTEIN

(Bacteroides
vulgatus) 		PF07470
(Glyco_hydro_88) 		4 LEU A 362
ALA A 364
TRP A 318
LEU A 321
 None
 1.23A 2oaxA-4q88A:
undetectable		 2oaxA-4q88A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u83 ACYL-COA
DEHYDROGENASE

(Brucella
abortus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LEU A  71
ALA A  70
LEU A  62
MET A  94
 None
None
EDO  A 401 ( 4.9A)
None
 1.24A 2oaxA-4u83A:
undetectable		 2oaxA-4u83A:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4udb MINERALOCORTICOID
RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 769
ALA A 773
TRP A 806
LEU A 810
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
 0.28A 2oaxA-4udbA:
36.3		 2oaxA-4udbA:
91.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwm 3,6-DIKETOCAMPHANE
1,6 MONOOXYGENASE

(Pseudomonas
putida) 		PF00296
(Bac_luciferase) 		4 LEU A  59
ALA A  62
TRP A  94
LEU A  95
 None
 1.16A 2oaxA-4uwmA:
undetectable		 2oaxA-4uwmA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd1 ACETOACETATE-COA
LIGASE

(Streptomyces
lividans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 LEU A 164
ALA A 162
TRP A 246
LEU A 134
 None
None
EDO  A 710 (-4.0A)
None
 1.18A 2oaxA-4wd1A:
undetectable		 2oaxA-4wd1A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49

(Mus musculus) 		PF03281
(Mab-21) 		4 LEU A 288
ALA A 302
TRP A 320
LEU A 304
 None
 1.12A 2oaxA-4woyA:
undetectable		 2oaxA-4woyA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		4 LEU A 262
ALA A 271
TRP A 301
LEU A 691
 None
 1.23A 2oaxA-4x6kA:
undetectable		 2oaxA-4x6kA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysj CALMODULIN-LIKE
DOMAIN PROTEIN
KINASE

(Eimeria tenella) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 LEU A 420
ALA A 423
LEU A 328
MET A 409
 None
 1.23A 2oaxA-4ysjA:
undetectable		 2oaxA-4ysjA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE

(Vesicular
stomatitis
virus) 		PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap) 		4 LEU A1250
ALA A1252
TRP A2107
LEU A1273
 None
 1.24A 2oaxA-5a22A:
undetectable		 2oaxA-5a22A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c78 ATP-DRIVEN FLIPPASE
PGLK

(Campylobacter
jejuni) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 LEU A 163
ALA A 165
LEU A 169
MET A  39
 None
 1.25A 2oaxA-5c78A:
undetectable		 2oaxA-5c78A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ek8 LIPOXYGENASE

(Cyanothece sp.
PCC 8801) 		PF00305
(Lipoxygenase) 		4 LEU A 458
ALA A 456
TRP A 572
LEU A 568
 None
 1.22A 2oaxA-5ek8A:
undetectable		 2oaxA-5ek8A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvb WD REPEAT AND
HMG-BOX DNA-BINDING
PROTEIN 1

(Homo sapiens) 		PF12341
(Mcl1_mid) 		4 LEU A 787
ALA A 785
LEU A 769
MET A 725
 None
 1.05A 2oaxA-5gvbA:
undetectable		 2oaxA-5gvbA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30

(Danio rerio) 		PF00443
(UCH) 		4 ALA A 430
TRP A 463
LEU A 428
MET A 492
 None
 1.17A 2oaxA-5gviA:
undetectable		 2oaxA-5gviA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gwj DNA TOPOISOMERASE
2-BETA

(Homo sapiens) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		4 LEU A1184
ALA A1186
LEU A 832
MET A 863
 None
 1.04A 2oaxA-5gwjA:
undetectable		 2oaxA-5gwjA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hop LMO0182 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 LEU A 171
ALA A 190
LEU A 193
MET A 160
 None
 1.23A 2oaxA-5hopA:
undetectable		 2oaxA-5hopA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		4 LEU A 986
ALA A 984
LEU A 981
MET A 932
 None
 1.21A 2oaxA-5i6hA:
undetectable		 2oaxA-5i6hA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ido 3' TERMINAL URIDYLYL
TRANSFERASE

(Trypanosoma
brucei) 		PF03828
(PAP_assoc) 		4 LEU A 452
ALA A 448
LEU A 401
MET A 427
 None
 0.88A 2oaxA-5idoA:
undetectable		 2oaxA-5idoA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ine PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX

(Lymphocytic
choriomeningitis
mammarenavirus) 		PF00798
(Arena_glycoprot) 		4 LEU A 329
ALA A 327
TRP A 270
MET A 290
 None
 1.17A 2oaxA-5ineA:
undetectable		 2oaxA-5ineA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lew DNA POLYMERASE III
SUBUNIT ALPHA

(Mycobacterium
tuberculosis) 		no annotation 4 LEU A 287
ALA A 290
LEU A  13
MET A 271
 None
 1.18A 2oaxA-5lewA:
undetectable		 2oaxA-5lewA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg3 PROTEIN TRANSLOCASE
SUBUNIT SECD

(Escherichia
coli) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG)
PF13721
(SecD-TM1) 		4 LEU D 424
ALA D 428
LEU D 279
MET D 365
 None
 0.95A 2oaxA-5mg3D:
undetectable		 2oaxA-5mg3D:
16.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mwp MINERALOCORTICOID
RECEPTOR

(Homo sapiens) 		no annotation 4 LEU A 769
ALA A 773
TRP A 806
MET A 852
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
None
ECV  A1101 (-3.7A)
 0.64A 2oaxA-5mwpA:
38.4		 2oaxA-5mwpA:
73.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5noa FAMILY 88 GLYCOSYL
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF07470
(Glyco_hydro_88) 		4 LEU A 365
ALA A 367
TRP A 321
LEU A 324
 None
 1.22A 2oaxA-5noaA:
undetectable		 2oaxA-5noaA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1

(Rhodobacter
sphaeroides) 		PF00016
(RuBisCO_large)
PF00101
(RuBisCO_small)
PF02788
(RuBisCO_large_N) 		4 LEU A 425
ALA A 427
LEU A 430
MET I  96
 None
 1.26A 2oaxA-5nv3A:
undetectable		 2oaxA-5nv3A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o2m BREAST CANCER
ANTI-ESTROGEN
RESISTANCE 1

(Homo sapiens) 		PF00018
(SH3_1) 		4 LEU A  65
ALA A  10
TRP A  46
LEU A  62
 None
 1.25A 2oaxA-5o2mA:
undetectable		 2oaxA-5o2mA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oe7 UBIQUITIN
THIOESTERASE OTULIN

(Homo sapiens) 		PF16218
(Peptidase_C101) 		4 LEU A 332
ALA A 130
LEU A 131
MET A 139
 None
 1.21A 2oaxA-5oe7A:
undetectable		 2oaxA-5oe7A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogs WD REPEAT AND
HMG-BOX DNA-BINDING
PROTEIN 1

(Homo sapiens) 		no annotation 4 LEU A 787
ALA A 785
LEU A 769
MET A 725
 None
 1.06A 2oaxA-5ogsA:
undetectable		 2oaxA-5ogsA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5q SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE
SDR:GLUCOSE/RIBITOL
DEHYDROGENASE

(Brucella
abortus) 		PF13561
(adh_short_C2) 		4 LEU A 126
ALA A 125
LEU A 121
MET A 163
 None
 1.11A 2oaxA-5t5qA:
undetectable		 2oaxA-5t5qA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5toa ESTROGEN RECEPTOR
BETA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 298
ALA A 302
TRP A 335
LEU A 339
 EST  A 601 (-4.1A)
EST  A 601 ( 3.9A)
None
EST  A 601 (-3.9A)
 0.52A 2oaxA-5toaA:
25.1		 2oaxA-5toaA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tul TETRACYCLINE
DESTRUCTASE TET(55)

(uncultured
bacterium) 		PF01494
(FAD_binding_3) 		4 LEU A 306
ALA A 309
LEU A  19
MET A 113
 None
 1.20A 2oaxA-5tulA:
undetectable		 2oaxA-5tulA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zqe -

(-) 		no annotation 4 LEU A  67
ALA A  65
LEU A  62
MET A 148
 None
 1.24A 2oaxA-5zqeA:
undetectable		 2oaxA-5zqeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cmz DIHYDROLIPOYL
DEHYDROGENASE

(Burkholderia
cenocepacia) 		no annotation 4 LEU A 454
ALA A 452
TRP A 408
LEU A 449
 None
 1.25A 2oaxA-6cmzA:
undetectable		 2oaxA-6cmzA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Pseudomonas
putida) 		no annotation 4 LEU A  29
ALA A  31
LEU A 197
MET A 232
 None
 1.25A 2oaxA-6cn1A:
undetectable		 2oaxA-6cn1A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gnf -

(-) 		no annotation 4 LEU A 119
ALA A 117
LEU A 156
MET A 178
 None
 1.24A 2oaxA-6gnfA:
undetectable		 2oaxA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gnf -

(-) 		no annotation 4 LEU A 119
ALA A 117
TRP A 237
LEU A 156
 None
 1.23A 2oaxA-6gnfA:
undetectable		 2oaxA-6gnfA:
undetectable