SIMILAR PATTERNS OF AMINO ACIDS FOR 2OA1_B_ADNB2005_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ctm | CYTOCHROME F (Brassica rapa) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 4 | GLY A 235GLY A 234VAL A 31SER A 28 | None | 0.67A | 2oa1B-1ctmA:undetectable | 2oa1B-1ctmA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fn9 | OUTER-CAPSID PROTEINSIGMA 3 (Reovirus sp.) |
PF00979(Reovirus_cap) | 4 | GLY A 319GLY A 318VAL A 302LEU A 5 | None | 0.75A | 2oa1B-1fn9A:undetectable | 2oa1B-1fn9A:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gqr | ACETYLCHOLINESTERASE (Tetronarcecalifornica) |
PF00135(COesterase) | 4 | GLY A 202VAL A 323SER A 228LEU A 404 | None | 0.83A | 2oa1B-1gqrA:undetectable | 2oa1B-1gqrA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ism | BONE MARROW STROMALCELL ANTIGEN 1 (Homo sapiens) |
PF02267(Rib_hydrolayse) | 4 | GLY A 200GLY A 199ASP A 230VAL A 203 | None | 0.70A | 2oa1B-1ismA:undetectable | 2oa1B-1ismA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1krh | BENZOATE1,2-DIOXYGENASEREDUCTASE (Acinetobactersp.) |
PF00111(Fer2)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 4 | GLY A 218GLY A 219VAL A 316LEU A 306 | NoneSO4 A 402 (-3.5A)NoneNone | 0.60A | 2oa1B-1krhA:3.7 | 2oa1B-1krhA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p0n | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Bacillussubtilis) |
PF01070(FMN_dh) | 4 | GLY A 258GLY A 259VAL A 186SER A 257 | FMN A 669 (-3.0A)FMN A 669 (-4.2A)NoneNone | 0.80A | 2oa1B-1p0nA:undetectable | 2oa1B-1p0nA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pox | PYRUVATE OXIDASE (Lactobacillusplantarum) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLY A 87GLY A 86VAL A 165LEU A 94 | None | 0.68A | 2oa1B-1poxA:2.3 | 2oa1B-1poxA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1r | PUTIDAREDOXINREDUCTASE (Pseudomonasputida) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 4 | GLY A 156GLY A 157VAL A 214LEU A 117 | None | 0.67A | 2oa1B-1q1rA:11.0 | 2oa1B-1q1rA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1smk | MALATEDEHYDROGENASE,GLYOXYSOMAL (Citrulluslanatus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 218GLY A 219VAL A 302LEU A 325 | None | 0.82A | 2oa1B-1smkA:undetectable | 2oa1B-1smkA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xt0 | GUANINE NUCLEOTIDEEXCHANGE PROTEIN (Legionellapneumophila) |
PF01369(Sec7) | 4 | GLY B 169GLY B 168VAL B 126LEU B 135 | None | 0.77A | 2oa1B-1xt0B:undetectable | 2oa1B-1xt0B:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yjk | PEPTIDYL-GLYCINEALPHA-AMIDATINGMONOOXYGENASE (Rattusnorvegicus) |
PF01082(Cu2_monooxygen)PF03712(Cu2_monoox_C) | 4 | GLY A 159GLY A 160VAL A 94SER A 164 | NoneNoneNoneGOL A 702 (-2.6A) | 0.84A | 2oa1B-1yjkA:undetectable | 2oa1B-1yjkA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytu | HYPOTHETICAL PROTEINAF1318 (Archaeoglobusfulgidus) |
PF02171(Piwi) | 4 | GLY A 110VAL A 100SER A 136LEU A 130 | None | 0.82A | 2oa1B-1ytuA:undetectable | 2oa1B-1ytuA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aj4 | GALACTOKINASE (Saccharomycescerevisiae) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | GLY A 472GLY A 471SER A 166LEU A 168 | NoneNoneANP A 532 (-3.9A)None | 0.79A | 2oa1B-2aj4A:undetectable | 2oa1B-2aj4A:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2azq | CATECHOL1,2-DIOXYGENASE (Pseudomonasputida) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 4 | GLY A 98GLY A 97ASP A 88LEU A 233 | None | 0.56A | 2oa1B-2azqA:undetectable | 2oa1B-2azqA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dqw | DIHYDROPTEROATESYNTHASE (Thermusthermophilus) |
PF00809(Pterin_bind) | 4 | GLY A 103ASP A 21VAL A 106LEU A 100 | None | 0.74A | 2oa1B-2dqwA:undetectable | 2oa1B-2dqwA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ejw | HOMOSERINEDEHYDROGENASE (Thermusthermophilus) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 4 | GLY A 15GLY A 12VAL A 71LEU A 298 | None | 0.72A | 2oa1B-2ejwA:4.1 | 2oa1B-2ejwA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gqt | UDP-N-ACETYLENOLPYRUVYLGLUCOSAMINEREDUCTASE (Thermuscaldophilus) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | GLY A 19GLY A 20VAL A 246LEU A 51 | None | 0.65A | 2oa1B-2gqtA:undetectable | 2oa1B-2gqtA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hig | 6-PHOSPHO-1-FRUCTOKINASE (Trypanosomabrucei) |
PF00365(PFK) | 4 | GLY A 106GLY A 107VAL A 103SER A 172 | None | 0.69A | 2oa1B-2higA:undetectable | 2oa1B-2higA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hjh | NAD-DEPENDENTHISTONE DEACETYLASESIR2 (Saccharomycescerevisiae) |
PF02146(SIR2)PF04574(DUF592) | 4 | GLY A 471GLY A 264VAL A 500LEU A 494 | XYQ A1222 (-3.6A)XYQ A1222 (-3.4A)NoneNone | 0.77A | 2oa1B-2hjhA:2.5 | 2oa1B-2hjhA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ie8 | PHOSPHOGLYCERATEKINASE (Thermuscaldophilus) |
PF00162(PGK) | 4 | GLY A 370GLY A 371VAL A 351ARG A 34 | None | 0.79A | 2oa1B-2ie8A:undetectable | 2oa1B-2ie8A:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jis | CYSTEINE SULFINICACID DECARBOXYLASE (Homo sapiens) |
PF00282(Pyridoxal_deC) | 4 | GLY A 246VAL A 280SER A 245LEU A 290 | None | 0.82A | 2oa1B-2jisA:undetectable | 2oa1B-2jisA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p97 | HYPOTHETICAL PROTEIN (Trichormusvariabilis) |
PF14597(Lactamase_B_5) | 4 | GLY A 145GLY A 144VAL A 138LEU A 195 | None | 0.80A | 2oa1B-2p97A:undetectable | 2oa1B-2p97A:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pg6 | CYTOCHROME P450 2A6 (Homo sapiens) |
PF00067(p450) | 4 | GLY A 302GLY A 301VAL A 181LEU A 444 | HEM A 500 (-3.5A)HEM A 500 ( 4.7A)NoneHEM A 500 ( 4.7A) | 0.78A | 2oa1B-2pg6A:undetectable | 2oa1B-2pg6A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qqh | COMPLEMENT COMPONENTC8 ALPHA CHAIN (Homo sapiens) |
PF01823(MACPF) | 4 | GLY A 319GLY A 318ASP A 428VAL A 235 | None | 0.78A | 2oa1B-2qqhA:undetectable | 2oa1B-2qqhA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qy0 | COMPLEMENT C1RSUBCOMPONENT (Homo sapiens) |
PF00089(Trypsin) | 4 | GLY B 472GLY B 639VAL B 502LEU B 544 | None | 0.79A | 2oa1B-2qy0B:undetectable | 2oa1B-2qy0B:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 4 | GLY A 649ASP A 608VAL A 666LEU A 658 | None | 0.84A | 2oa1B-2vdcA:undetectable | 2oa1B-2vdcA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wrt | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME 51 (Fasciolahepatica) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | GLY A 211GLY A 212VAL A 109LEU A 165 | None | 0.83A | 2oa1B-2wrtA:undetectable | 2oa1B-2wrtA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | GLY A 231GLY A 230VAL A 137LEU A 345 | HEM A1400 (-3.2A)PG4 A1399 ( 3.2A)NoneHEM A1400 ( 4.7A) | 0.70A | 2oa1B-2xkrA:undetectable | 2oa1B-2xkrA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsb | HYALURONOGLUCOSAMINIDASE (Oceanicolagranulosus) |
PF07555(NAGidase) | 4 | GLY A 239GLY A 238ASP A 220VAL A 201 | None | 0.83A | 2oa1B-2xsbA:undetectable | 2oa1B-2xsbA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zec | TRYPTASE BETA 2 (Homo sapiens) |
PF00089(Trypsin) | 4 | GLY A 46GLY A 211VAL A 73LEU A 110 | None | 0.76A | 2oa1B-2zecA:undetectable | 2oa1B-2zecA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ada | SARCOSINE OXIDASEBETA SUBUNIT (Corynebacteriumsp. U-96) |
PF01266(DAO) | 4 | GLY B 27GLY B 28VAL B 196LEU B 232 | FAD B 1 (-3.3A)FAD B 1 ( 4.8A)FAD B 1 (-4.0A)FAD B 1 (-4.6A) | 0.68A | 2oa1B-3adaB:13.9 | 2oa1B-3adaB:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afo | NADH KINASE POS5 (Saccharomycescerevisiae) |
PF01513(NAD_kinase) | 4 | GLY A 275GLY A 274VAL A 278LEU A 286 | None | 0.69A | 2oa1B-3afoA:4.7 | 2oa1B-3afoA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c19 | UNCHARACTERIZEDPROTEIN MK0293 (Methanopyruskandleri) |
PF01969(DUF111) | 4 | GLY A 63GLY A 64VAL A 74ARG A 89 | None | 0.65A | 2oa1B-3c19A:5.2 | 2oa1B-3c19A:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c8v | PUTATIVEACETYLTRANSFERASE (Desulfovibrioalaskensis) |
no annotation | 4 | GLY A 319GLY A 318VAL A 354LEU A 338 | None | 0.79A | 2oa1B-3c8vA:undetectable | 2oa1B-3c8vA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cbt | PHOSPHATASE SC4828 (Streptomycescoelicolor) |
PF04167(DUF402) | 4 | GLY A 144GLY A 143VAL A 61LEU A 59 | GLY A 144 ( 0.0A)GLY A 143 ( 0.0A)VAL A 61 ( 0.6A)LEU A 59 ( 0.6A) | 0.78A | 2oa1B-3cbtA:undetectable | 2oa1B-3cbtA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cer | POSSIBLEEXOPOLYPHOSPHATASE-LIKE PROTEIN (Bifidobacteriumlongum) |
PF02541(Ppx-GppA) | 4 | GLY A 154GLY A 155VAL A 231ARG A 29 | SO4 A 345 (-3.4A)SO4 A 345 ( 3.5A)NoneSO4 A 345 (-2.8A) | 0.82A | 2oa1B-3cerA:undetectable | 2oa1B-3cerA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ch7 | 6-PHOSPHOGLUCONOLACTONASE (Leishmaniabraziliensis) |
PF01182(Glucosamine_iso) | 4 | GLY A 122GLY A 121SER A 116LEU A 78 | None | 0.75A | 2oa1B-3ch7A:undetectable | 2oa1B-3ch7A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cin | MYO-INOSITOL-1-PHOSPHATESYNTHASE-RELATEDPROTEIN (Thermotogamaritima) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 4 | GLY A 10ASP A 244VAL A 182LEU A 320 | NAD A 400 (-3.2A)NAD A 400 (-3.5A)NoneNAD A 400 (-4.2A) | 0.71A | 2oa1B-3cinA:undetectable | 2oa1B-3cinA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cty | THIOREDOXINREDUCTASE (Thermoplasmaacidophilum) |
PF07992(Pyr_redox_2) | 4 | GLY A 162GLY A 163VAL A 213LEU A 129 | None | 0.60A | 2oa1B-3ctyA:9.1 | 2oa1B-3ctyA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3da1 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE (Bacillushalodurans) |
PF01266(DAO)PF16901(DAO_C) | 4 | GLY A 25GLY A 26VAL A 193LEU A 235 | FAD A 609 ( 4.0A)NoneFAD A 609 ( 3.8A)FAD A 609 (-4.2A) | 0.63A | 2oa1B-3da1A:9.2 | 2oa1B-3da1A:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e1t | HALOGENASE (Chondromycescrocatus) |
PF04820(Trp_halogenase) | 4 | GLY A 14GLY A 15VAL A 134SER A 168 | FAD A 600 (-3.2A)FAD A 600 ( 4.9A)FAD A 600 (-3.9A)FAD A 600 (-4.2A) | 0.60A | 2oa1B-3e1tA:25.6 | 2oa1B-3e1tA:25.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fah | ALDEHYDEOXIDOREDUCTASE (Desulfovibriogigas) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 4 | GLY A 696GLY A 697ASP A 630SER A 695 | GOL A 912 ( 3.1A)GOL A 912 ( 3.1A)NonePCD A 921 (-4.4A) | 0.83A | 2oa1B-3fahA:undetectable | 2oa1B-3fahA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gi8 | UNCHARACTERIZEDPROTEIN MJ0609 (Methanocaldococcusjannaschii) |
PF13520(AA_permease_2) | 4 | GLY C 31VAL C 343SER C 28LEU C 103 | None | 0.82A | 2oa1B-3gi8C:undetectable | 2oa1B-3gi8C:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3glg | DNA POLYMERASE IIISUBUNIT DELTA' (Escherichiacoli) |
PF09115(DNApol3-delta_C)PF13177(DNA_pol3_delta2) | 4 | GLY E 108GLY E 107VAL E 111LEU E 49 | None | 0.80A | 2oa1B-3glgE:undetectable | 2oa1B-3glgE:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h3j | L-LACTATEDEHYDROGENASE 1 (Staphylococcusaureus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 18GLY A 15VAL A 79LEU A 240 | NoneNAD A 500 (-3.3A)NoneNone | 0.81A | 2oa1B-3h3jA:3.4 | 2oa1B-3h3jA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hut | PUTATIVEBRANCHED-CHAIN AMINOACID ABC TRANSPORTER (Rhodospirillumrubrum) |
PF13458(Peripla_BP_6) | 4 | GLY A 76GLY A 75VAL A 329LEU A 41 | None | 0.80A | 2oa1B-3hutA:3.7 | 2oa1B-3hutA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne5 | CATION EFFLUX SYSTEMPROTEIN CUSA (Escherichiacoli) |
PF00873(ACR_tran) | 4 | GLY A 181GLY A 182ASP A 161VAL A 288 | None | 0.72A | 2oa1B-3ne5A:undetectable | 2oa1B-3ne5A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pko | GERANYLGERANYLPYROPHOSPHATESYNTHASE (Lactobacillusbrevis) |
PF00348(polyprenyl_synt) | 4 | GLY A 45GLY A 46VAL A 99LEU A 41 | None | 0.82A | 2oa1B-3pkoA:undetectable | 2oa1B-3pkoA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3red | HYDROXYNITRILE LYASE (Prunus mume) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | GLY A 104GLY A 105VAL A 211LEU A 201 | NoneFAD A 773 (-3.3A)NoneNone | 0.72A | 2oa1B-3redA:8.9 | 2oa1B-3redA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3suc | PRENECK APPENDAGEPROTEIN (Bacillus virusphi29) |
PF11962(Peptidase_G2)PF12708(Pectate_lyase_3) | 4 | GLY A 464GLY A 465VAL A 436ARG A 441 | None | 0.77A | 2oa1B-3sucA:undetectable | 2oa1B-3sucA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u3z | MICROCEPHALIN (Homo sapiens) |
PF00533(BRCT)PF16589(BRCT_2) | 4 | GLY A 798VAL A 816SER A 768LEU A 775 | None | 0.62A | 2oa1B-3u3zA:undetectable | 2oa1B-3u3zA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2h | D-BETA-HYDROXYBUTYRATE DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | GLY A 13VAL A 47SER A 10LEU A 31 | None | 0.77A | 2oa1B-3v2hA:5.1 | 2oa1B-3v2hA:23.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfz | LACTO-N-BIOSEPHOSPHORYLASE (Bifidobacteriumlongum) |
PF09508(Lact_bio_phlase)PF17385(LBP_M)PF17386(LBP_C) | 4 | GLY A 516VAL A 529SER A 546LEU A 559 | None | 0.65A | 2oa1B-3wfzA:undetectable | 2oa1B-3wfzA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqu | CELL DIVISIONPROTEIN FTSA (Staphylococcusaureus) |
PF02491(SHS2_FTSA)PF14450(FtsA) | 4 | GLY A 201GLY A 318VAL A 223LEU A 313 | None | 0.78A | 2oa1B-3wquA:undetectable | 2oa1B-3wquA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zby | P450 HEME-THIOLATEPROTEIN (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 4 | GLY A 234GLY A 233VAL A 140LEU A 348 | HEM A1402 (-3.3A)EDO A1406 ( 3.4A)NoneHEM A1402 ( 4.7A) | 0.68A | 2oa1B-3zbyA:undetectable | 2oa1B-3zbyA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bv6 | APOPTOSIS-INDUCINGFACTOR 1,MITOCHONDRIAL (Homo sapiens) |
PF07992(Pyr_redox_2)PF14721(AIF_C) | 4 | GLY A 307GLY A 308VAL A 369LEU A 267 | None | 0.62A | 2oa1B-4bv6A:10.2 | 2oa1B-4bv6A:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7p | RALF (Legionellapneumophila) |
PF01369(Sec7) | 4 | GLY A 169GLY A 168VAL A 126LEU A 135 | None | 0.65A | 2oa1B-4c7pA:2.8 | 2oa1B-4c7pA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gk9 | AGGLUTININ (BOA) (Burkholderiaoklahomensis) |
no annotation | 4 | GLY A 29GLY A 28VAL A 99LEU A 232 | None | 0.78A | 2oa1B-4gk9A:undetectable | 2oa1B-4gk9A:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpz | DTALE2 (Xanthomonas) |
PF03377(TAL_effector) | 4 | GLY A 371GLY A 370VAL A 344SER A 367 | None | 0.82A | 2oa1B-4hpzA:undetectable | 2oa1B-4hpzA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpz | DTALE2 (Xanthomonas) |
PF03377(TAL_effector) | 4 | GLY A 507GLY A 506VAL A 480SER A 503 | None | 0.80A | 2oa1B-4hpzA:undetectable | 2oa1B-4hpzA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i1u | DEPHOSPHO-COA KINASE (Burkholderiavietnamiensis) |
PF01121(CoaE) | 4 | GLY A 8GLY A 9VAL A 17LEU A 6 | None | 0.82A | 2oa1B-4i1uA:2.9 | 2oa1B-4i1uA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iao | NAD-DEPENDENTHISTONE DEACETYLASESIR2 (Saccharomycescerevisiae) |
PF02146(SIR2)PF04574(DUF592) | 4 | GLY A 471GLY A 264VAL A 500LEU A 494 | APR A 602 (-3.7A)APR A 602 (-3.3A)NoneNone | 0.79A | 2oa1B-4iaoA:2.6 | 2oa1B-4iaoA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9v | POTASSIUM UPTAKEPROTEIN TRKA (Vibrioparahaemolyticus) |
PF02080(TrkA_C)PF02254(TrkA_N) | 4 | GLY A 12GLY A 9VAL A 70LEU A 358 | NoneAGS A 501 (-3.4A)NoneNone | 0.79A | 2oa1B-4j9vA:6.3 | 2oa1B-4j9vA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdz | SER-ASP RICHFIBRINOGEN/BONESIALOPROTEIN-BINDINGPROTEIN SDRD (Staphylococcusaureus) |
PF10425(SdrG_C_C)PF17210(SdrD_B) | 4 | GLY A 609GLY A 608ASP A 665LEU A 611 | NoneNone CA A 702 (-2.3A)None | 0.82A | 2oa1B-4jdzA:undetectable | 2oa1B-4jdzA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3x | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | GLY A 249GLY A 200VAL A 130LEU A 164 | None | 0.72A | 2oa1B-4k3xA:undetectable | 2oa1B-4k3xA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kem | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Azospirillumlipoferum) |
PF13378(MR_MLE_C) | 4 | GLY A 338GLY A 337VAL A 363LEU A 328 | None | 0.74A | 2oa1B-4kemA:undetectable | 2oa1B-4kemA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l5o | PUTATIVE GLUTATHIONETRANSFERASE (Clonorchissinensis) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | GLY A 211GLY A 212VAL A 106LEU A 165 | None | 0.76A | 2oa1B-4l5oA:undetectable | 2oa1B-4l5oA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l9z | MALYL-COA LYASE (Rhodobactersphaeroides) |
PF03328(HpcH_HpaI) | 4 | GLY A 181GLY A 182ASP A 199LEU A 164 | None | 0.80A | 2oa1B-4l9zA:undetectable | 2oa1B-4l9zA:22.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lu6 | FLAVIN-DEPENDENTTRYPTOPHANHALOGENASE REBH (Lechevalieriaaerocolonigenes) |
PF04820(Trp_halogenase) | 5 | GLY A 12GLY A 13ASP A 41SER A 228ARG A 231 | None | 0.80A | 2oa1B-4lu6A:62.2 | 2oa1B-4lu6A:98.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lu6 | FLAVIN-DEPENDENTTRYPTOPHANHALOGENASE REBH (Lechevalieriaaerocolonigenes) |
PF04820(Trp_halogenase) | 6 | GLY A 12GLY A 13ASP A 41VAL A 197SER A 228LEU A 233 | None | 0.52A | 2oa1B-4lu6A:62.2 | 2oa1B-4lu6A:98.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mc5 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | GLY A 247GLY A 198VAL A 129LEU A 162 | None | 0.81A | 2oa1B-4mc5A:undetectable | 2oa1B-4mc5A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mo9 | PERIPLASMIC BINDINGPROTEIN (Veillonellaparvula) |
PF01497(Peripla_BP_2) | 4 | GLY A 47GLY A 46SER A 43LEU A 40 | None | 0.83A | 2oa1B-4mo9A:2.5 | 2oa1B-4mo9A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opu | CONSERVED ARCHAEALPROTEIN (Sulfolobusacidocaldarius) |
PF01266(DAO) | 4 | GLY A 234GLY A 235VAL A 269ARG A 351 | NoneNoneFDA A 501 ( 4.7A)None | 0.76A | 2oa1B-4opuA:21.2 | 2oa1B-4opuA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pyt | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (unidentified) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | GLY A 31GLY A 32VAL A 273LEU A 70 | None | 0.82A | 2oa1B-4pytA:undetectable | 2oa1B-4pytA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q80 | SERINE PROTEASE 57 (Homo sapiens) |
PF00089(Trypsin) | 4 | GLY A 44GLY A 197VAL A 66LEU A 106 | None | 0.81A | 2oa1B-4q80A:undetectable | 2oa1B-4q80A:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uta | BROADLY NEUTRALIZINGHUMAN ANTIBODY EDE1C8 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY H 98GLY H 99ARG H 72LEU H 79 | None | 0.68A | 2oa1B-4utaH:undetectable | 2oa1B-4utaH:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4utg | SUGAR KINASE (Burkholderiapseudomallei) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | GLY A 304GLY A 303SER A 114LEU A 116 | NoneNone MG A 400 (-2.4A) MG A 400 ( 4.6A) | 0.80A | 2oa1B-4utgA:undetectable | 2oa1B-4utgA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8i | PROBABLESPHINGOSINE-1-PHOSPHATE LYASE (Legionellapneumophila) |
PF00282(Pyridoxal_deC) | 4 | GLY A 331GLY A 330ASP A 326VAL A 370 | None | 0.83A | 2oa1B-4w8iA:undetectable | 2oa1B-4w8iA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x0q | DNA POLYMERASE THETA (Homo sapiens) |
PF00476(DNA_pol_A) | 4 | GLY A2532GLY A2531VAL A2558LEU A2327 | None | 0.59A | 2oa1B-4x0qA:2.5 | 2oa1B-4x0qA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x9n | L-ALPHA-GLYCEROPHOSPHATE OXIDASE (Mycoplasmapneumoniae) |
PF01266(DAO) | 4 | GLY A 10GLY A 11VAL A 177LEU A 216 | FAD A 401 (-3.2A)FAD A 401 ( 4.6A)FAD A 401 (-4.2A)None | 0.78A | 2oa1B-4x9nA:13.2 | 2oa1B-4x9nA:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ysh | GLYCINE OXIDASE (Geobacilluskaustophilus) |
PF01266(DAO) | 4 | GLY A 11GLY A 12VAL A 180SER A 208 | FAD A 401 (-3.3A)FAD A 401 ( 4.8A)FAD A 401 (-4.0A)FAD A 401 (-4.4A) | 0.44A | 2oa1B-4yshA:13.7 | 2oa1B-4yshA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ysj | CALMODULIN-LIKEDOMAIN PROTEINKINASE (Eimeria tenella) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | GLY A 214VAL A 135SER A 212LEU A 152 | None | 0.79A | 2oa1B-4ysjA:undetectable | 2oa1B-4ysjA:22.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4z43 | FLAVIN-DEPENDENTTRYPTOPHANHALOGENASE PRNA (Pseudomonasfluorescens) |
PF04820(Trp_halogenase) | 4 | GLY A 12GLY A 13VAL A 187SER A 218 | FAD A 601 (-3.2A)FAD A 601 (-3.3A)FAD A 601 (-3.8A)FAD A 601 (-4.9A) | 0.29A | 2oa1B-4z43A:52.7 | 2oa1B-4z43A:53.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4z43 | FLAVIN-DEPENDENTTRYPTOPHANHALOGENASE PRNA (Pseudomonasfluorescens) |
PF04820(Trp_halogenase) | 4 | GLY A 12VAL A 187SER A 218LEU A 223 | FAD A 601 (-3.2A)FAD A 601 (-3.8A)FAD A 601 (-4.9A)FAD A 601 (-3.7A) | 0.51A | 2oa1B-4z43A:52.7 | 2oa1B-4z43A:53.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5q | CYTOCHROME P450HYDROXYLASE (Streptomycesatroolivaceus) |
PF00067(p450) | 4 | GLY A 241GLY A 240VAL A 152LEU A 357 | HEM A 401 (-3.2A)P33 A 407 ( 3.4A)NoneHEM A 401 (-4.6A) | 0.78A | 2oa1B-4z5qA:undetectable | 2oa1B-4z5qA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5buk | FADH2-DEPENDENTHALOGENASE (Streptomycessp. CNQ-418) |
PF04820(Trp_halogenase) | 4 | GLY A 11GLY A 12VAL A 146SER A 178 | FAD A 501 (-3.3A)FAD A 501 ( 4.9A)FAD A 501 (-4.0A)FAD A 501 (-4.6A) | 0.59A | 2oa1B-5bukA:23.2 | 2oa1B-5bukA:25.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eb5 | HNL ISOENZYME 5 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | GLY A 464GLY A 463ASP A 487LEU A 267 | NoneNoneFAD A 601 (-4.6A)None | 0.77A | 2oa1B-5eb5A:8.4 | 2oa1B-5eb5A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iaa | UBIQUITIN-LIKEMODIFIER-ACTIVATINGENZYME 5 (Homo sapiens) |
PF00899(ThiF) | 4 | GLY A 83GLY A 82VAL A 207LEU A 254 | None | 0.79A | 2oa1B-5iaaA:6.6 | 2oa1B-5iaaA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja1 | ENTEROBACTINSYNTHASE COMPONENT F (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 4 | GLY A1004GLY A1003VAL A1029LEU A1012 | None | 0.76A | 2oa1B-5ja1A:2.2 | 2oa1B-5ja1A:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jwb | TYPE IINADH:UBIQUINONEOXIDOREDUCTASE (Plasmodiumfalciparum) |
PF07992(Pyr_redox_2) | 4 | GLY A 207GLY A 208VAL A 278SER A 309 | NAD A 608 (-3.3A)NAD A 608 ( 4.8A)NAD A 608 (-4.2A)NAD A 608 (-4.7A) | 0.48A | 2oa1B-5jwbA:9.8 | 2oa1B-5jwbA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k59 | UNCHARACTERIZEDLEUKOCIDIN-LIKEPROTEIN 2 (Staphylococcusaureus) |
no annotation | 4 | GLY D 149GLY D 148ASP D 75LEU D 126 | None | 0.74A | 2oa1B-5k59D:undetectable | 2oa1B-5k59D:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ko5 | PURINE NUCLEOSIDEPHOSPHORYLASE (Schistosomamansoni) |
PF01048(PNP_UDP_1) | 4 | GLY A 120GLY A 121ASP A 250VAL A 262 | CYT A 301 (-3.3A)NoneNoneNone | 0.77A | 2oa1B-5ko5A:undetectable | 2oa1B-5ko5A:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3r | CELL DIVISIONPROTEIN FTSYHOMOLOG,CHLOROPLASTICSIGNAL RECOGNITIONPARTICLE 54 KDAPROTEIN,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | GLY A 301ASP B 292VAL A 296LEU A 307 | None | 0.83A | 2oa1B-5l3rA:undetectable | 2oa1B-5l3rA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3r | CELL DIVISIONPROTEIN FTSYHOMOLOG,CHLOROPLASTICSIGNAL RECOGNITIONPARTICLE 54 KDAPROTEIN,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | GLY A 301GLY B 296ASP B 292VAL A 296 | None | 0.82A | 2oa1B-5l3rA:undetectable | 2oa1B-5l3rA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lbs | BROADLY NEUTRALIZINGHUMAN ANTIBODY EDE1C8 (Homo sapiens) |
PF07686(V-set) | 4 | GLY H 94GLY H 95ARG H 71LEU H 78 | NoneEDO H 202 ( 3.7A)NoneNone | 0.65A | 2oa1B-5lbsH:undetectable | 2oa1B-5lbsH:12.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkk | MULTIDRUG RESISTANCEABC TRANSPORTERATP-BINDING ANDPERMEASE PROTEIN (Thermusthermophilus) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | GLY B 564GLY B 563VAL B 551LEU A 602 | None | 0.80A | 2oa1B-5mkkB:undetectable | 2oa1B-5mkkB:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ohs | - (-) |
no annotation | 4 | GLY A 116GLY A 115VAL A 444SER A 476 | None | 0.64A | 2oa1B-5ohsA:undetectable | 2oa1B-5ohsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b74 | COAGULATION FACTORXII (Homo sapiens) |
no annotation | 4 | GLY B 44GLY B 197VAL B 66LEU B 106 | None | 0.83A | 2oa1B-6b74B:undetectable | 2oa1B-6b74B:10.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bhu | MULTIDRUGRESISTANCE-ASSOCIATED PROTEIN 1 (Bos taurus) |
no annotation | 4 | GLY A1425GLY A1426VAL A 420SER A1380 | None | 0.76A | 2oa1B-6bhuA:undetectable | 2oa1B-6bhuA:0.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6geb | DOTB (Legionellapneumophila) |
no annotation | 4 | GLY A 358ASP A 304VAL A 300SER A 361 | None | 0.80A | 2oa1B-6gebA:undetectable | 2oa1B-6gebA:8.74 |