SIMILAR PATTERNS OF AMINO ACIDS FOR 2O02_B_BEZB802

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yb4 AMIDOHYDROLASE

(Chromobacterium
violaceum) 		PF02811
(PHP) 		4 ILE A 132
MET A 106
GLN A 105
ARG A 104
 None
 1.41A 2o02B-2yb4A:
0.0		 2o02B-2yb4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7i SPARTIN

(Homo sapiens) 		PF04212
(MIT) 		4 ILE A  13
MET A  77
GLN A  76
ARG A  75
 None
 1.12A 2o02B-4u7iA:
5.9		 2o02B-4u7iA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC

(Arabidopsis
thaliana) 		PF02446
(Glyco_hydro_77) 		4 ILE A 418
MET A 441
GLN A 465
ARG A 433
 None
 1.42A 2o02B-5csuA:
0.0		 2o02B-5csuA:
17.58