SIMILAR PATTERNS OF AMINO ACIDS FOR 2NXE_A_SAMA302_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ao0 GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE

(Bacillus
subtilis) 		PF00156
(Pribosyltran)
PF13522
(GATase_6) 		3 THR A 388
ASP A 127
SER A 125
 SF4  A 466 ( 4.1A)
None
None
 0.47A 2nxeA-1ao0A:
3.1		 2nxeA-1ao0A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1azw PROLINE
IMINOPEPTIDASE

(Xanthomonas
citri) 		PF00561
(Abhydrolase_1) 		3 THR A 114
ASP A 266
SER A 289
 None
 0.72A 2nxeA-1azwA:
2.2		 2nxeA-1azwA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bkd SON OF SEVENLESS-1

(Homo sapiens) 		PF00617
(RasGEF)
PF00618
(RasGEF_N) 		3 THR S 605
ASP S 573
SER S 571
 None
 0.77A 2nxeA-1bkdS:
undetectable		 2nxeA-1bkdS:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ct9 ASPARAGINE
SYNTHETASE B

(Escherichia
coli) 		PF00733
(Asn_synthase)
PF13537
(GATase_7) 		3 THR A 373
ASP A 238
SER A 346
 None
IUM  A1101 ( 3.0A)
AMP  A1100 (-3.0A)
 0.79A 2nxeA-1ct9A:
1.9		 2nxeA-1ct9A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1czk FLAVODOXIN

(Synechococcus
elongatus) 		PF00258
(Flavodoxin_1) 		3 THR A 152
ASP A  90
SER A  95
 None
 0.80A 2nxeA-1czkA:
undetectable		 2nxeA-1czkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e9y UREASE SUBUNIT BETA

(Helicobacter
pylori) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		3 THR B 251
ASP B 362
SER B 360
 None
HAE  B 800 ( 2.5A)
None
 0.84A 2nxeA-1e9yB:
undetectable		 2nxeA-1e9yB:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbw ENDO-1,4-BETA-GLUCAN
ASE F

([Clostridium]
cellulolyticum) 		PF02011
(Glyco_hydro_48) 		3 THR A 334
ASP A 243
SER A 254
 None
 0.81A 2nxeA-1fbwA:
undetectable		 2nxeA-1fbwA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fue FLAVODOXIN

(Helicobacter
pylori) 		PF00258
(Flavodoxin_1) 		3 THR A 148
ASP A  88
SER A  93
 None
 0.77A 2nxeA-1fueA:
undetectable		 2nxeA-1fueA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jnf SEROTRANSFERRIN

(Oryctolagus
cuniculus) 		PF00405
(Transferrin) 		3 THR A 534
ASP A 392
SER A 390
 None
FE  A 703 ( 3.0A)
None
 0.85A 2nxeA-1jnfA:
undetectable		 2nxeA-1jnfA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 THR A 145
ASP A 490
SER A 497
 None
 0.84A 2nxeA-1kfiA:
undetectable		 2nxeA-1kfiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		3 THR A 529
ASP A 295
SER A 252
 None
CA  A 802 (-3.1A)
None
 0.86A 2nxeA-1kv9A:
undetectable		 2nxeA-1kv9A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l7p PHOSPHOSERINE
PHOSPHATASE

(Methanocaldococcus
jannaschii) 		PF12710
(HAD) 		3 THR A  39
ASP A 171
SER A 173
 SEP  A 770 (-3.7A)
SEP  A 770 ( 4.7A)
None
 0.76A 2nxeA-1l7pA:
2.4		 2nxeA-1l7pA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lth L-LACTATE
DEHYDROGENASE (T-
AND R- STATE
TETRAMER COMPLEX)

(Bifidobacterium
longum) 		no annotation 3 THR T 280
ASP T 128
SER T 306
 None
 0.84A 2nxeA-1lthT:
6.5		 2nxeA-1lthT:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lxt PHOSPHOGLUCOMUTASE
(DEPHOSPHO FORM)

(Oryctolagus
cuniculus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 THR A 274
ASP A 281
SER A 407
 None
 0.78A 2nxeA-1lxtA:
2.4		 2nxeA-1lxtA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m54 CYSTATHIONINE
BETA-SYNTHASE

(Homo sapiens) 		PF00291
(PALP) 		3 THR A 262
ASP A 281
SER A 326
 None
 0.86A 2nxeA-1m54A:
3.2		 2nxeA-1m54A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Bacillus
subtilis) 		PF08282
(Hydrolase_3) 		3 THR A 111
ASP A  47
SER A  63
 None
 0.85A 2nxeA-1nrwA:
undetectable		 2nxeA-1nrwA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvl LEUCOCIDIN

(Staphylococcus
aureus) 		PF07968
(Leukocidin) 		3 THR A 273
ASP A 154
SER A 152
 None
 0.68A 2nxeA-1pvlA:
undetectable		 2nxeA-1pvlA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qge PROTEIN
(TRIACYLGLYCEROL
HYDROLASE)

(Burkholderia
glumae) 		PF00561
(Abhydrolase_1) 		3 THR D  20
ASP D  55
SER D  93
 None
 0.83A 2nxeA-1qgeD:
2.2		 2nxeA-1qgeD:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs0 2-OXOISOVALERATE
DEHYDROGENASE
ALPHA-SUBUNIT

(Pseudomonas
putida) 		PF00676
(E1_dh)
PF12573
(OxoDH_E1alpha_N) 		3 THR A 179
ASP A 392
SER A 388
 None
 0.84A 2nxeA-1qs0A:
undetectable		 2nxeA-1qs0A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs0 2-OXOISOVALERATE
DEHYDROGENASE
ALPHA-SUBUNIT

(Pseudomonas
putida) 		PF00676
(E1_dh)
PF12573
(OxoDH_E1alpha_N) 		3 THR A 357
ASP A 143
SER A 145
 None
 0.75A 2nxeA-1qs0A:
undetectable		 2nxeA-1qs0A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1raj GENOME POLYPROTEIN

(Enterovirus C) 		PF00680
(RdRP_1) 		3 THR A 372
ASP A 328
SER A 294
 None
 0.78A 2nxeA-1rajA:
undetectable		 2nxeA-1rajA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sa3 TYPE II RESTRICTION
ENZYME MSPI

(Moraxella sp.) 		PF09208
(Endonuc-MspI) 		3 THR A  53
ASP A  44
SER A  82
 None
 0.83A 2nxeA-1sa3A:
undetectable		 2nxeA-1sa3A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suv SEROTRANSFERRIN,
C-LOBE

(Homo sapiens) 		PF00405
(Transferrin) 		3 THR E 534
ASP E 392
SER E 390
 None
FE  E 703 ( 3.0A)
None
 0.85A 2nxeA-1suvE:
undetectable		 2nxeA-1suvE:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tp7 GENOME POLYPROTEIN

(Rhinovirus A) 		PF00680
(RdRP_1) 		3 THR A 371
ASP A 327
SER A 293
 None
 0.75A 2nxeA-1tp7A:
undetectable		 2nxeA-1tp7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tp7 GENOME POLYPROTEIN

(Rhinovirus A) 		PF00680
(RdRP_1) 		3 THR A 371
ASP A 327
SER A 297
 None
 0.82A 2nxeA-1tp7A:
undetectable		 2nxeA-1tp7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vi7 HYPOTHETICAL PROTEIN
YIGZ

(Escherichia
coli) 		PF01205
(UPF0029)
PF09186
(DUF1949) 		3 THR A 133
ASP A  65
SER A  67
 None
 0.69A 2nxeA-1vi7A:
3.1		 2nxeA-1vi7A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vko INOSITOL-3-PHOSPHATE
SYNTHASE

(Caenorhabditis
elegans) 		PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5) 		3 THR A 492
ASP A 371
SER A 375
 None
 0.82A 2nxeA-1vkoA:
1.8		 2nxeA-1vkoA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w3f HEMOLYTIC LECTIN
FROM LAETIPORUS
SULPHUREUS

(Laetiporus
sulphureus) 		PF03318
(ETX_MTX2) 		3 THR A 309
ASP A 271
SER A 303
 None
 0.84A 2nxeA-1w3fA:
undetectable		 2nxeA-1w3fA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y0e PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE

(Staphylococcus
aureus) 		PF04131
(NanE) 		3 THR A  43
ASP A  65
SER A  69
 None
 0.74A 2nxeA-1y0eA:
undetectable		 2nxeA-1y0eA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzf LIPASE/ACYLHYDROLASE

(Enterococcus
faecalis) 		PF13472
(Lipase_GDSL_2) 		3 THR A  12
ASP A  79
SER A  81
 None
 0.57A 2nxeA-1yzfA:
undetectable		 2nxeA-1yzfA:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adu METHIONINE
AMINOPEPTIDASE 2

(Homo sapiens) 		PF00557
(Peptidase_M24) 		3 THR A 192
ASP A 202
SER A 204
 None
 0.67A 2nxeA-2aduA:
undetectable		 2nxeA-2aduA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bap DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		no annotation 3 THR B 297
ASP B 240
SER B 202
 None
 0.72A 2nxeA-2bapB:
undetectable		 2nxeA-2bapB:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bnx DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 THR A 297
ASP A 240
SER A 202
 None
 0.76A 2nxeA-2bnxA:
undetectable		 2nxeA-2bnxA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f31 DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 THR A 297
ASP A 240
SER A 202
 None
 0.74A 2nxeA-2f31A:
undetectable		 2nxeA-2f31A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6y GREEN FLUORESCENT
PROTEIN 2

(Pontellina
plumata) 		PF01353
(GFP) 		3 THR A  41
ASP A 113
SER A 100
 None
 0.81A 2nxeA-2g6yA:
undetectable		 2nxeA-2g6yA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gaf POLY(A) POLYMERASE
CATALYTIC SUBUNIT

(Vaccinia virus) 		PF03296
(Pox_polyA_pol)
PF12629
(Pox_polyA_pol_C)
PF12630
(Pox_polyA_pol_N) 		3 THR D 345
ASP D 369
SER D 367
 None
 0.77A 2nxeA-2gafD:
undetectable		 2nxeA-2gafD:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjm LACTOPEROXIDASE

(Bubalus bubalis) 		PF03098
(An_peroxidase) 		3 THR A 292
ASP A  98
SER A 325
 None
HEM  A 605 (-3.7A)
None
 0.80A 2nxeA-2gjmA:
undetectable		 2nxeA-2gjmA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gko MICROBIAL SERINE
PROTEINASES
SUBTILISIN

(Bacillus
subtilis) 		PF00082
(Peptidase_S8) 		3 THR A  61
ASP A 106
SER A 109
 None
 0.83A 2nxeA-2gkoA:
undetectable		 2nxeA-2gkoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h5j CASPASE-3, P17
SUBUNIT

(Homo sapiens) 		PF00656
(Peptidase_C14) 		3 THR A  92
ASP A 102
SER A 104
 None
 0.76A 2nxeA-2h5jA:
3.4		 2nxeA-2h5jA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5g AMIDOHYDROLASE

(Pseudomonas
aeruginosa) 		PF01244
(Peptidase_M19) 		3 THR A 264
ASP A 250
SER A 180
 None
 0.84A 2nxeA-2i5gA:
undetectable		 2nxeA-2i5gA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix5 ACYL-COENZYME A
OXIDASE 4,
PEROXISOMAL

(Arabidopsis
thaliana) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 THR A 224
ASP A 279
SER A 281
 None
None
CAA  A1432 ( 4.7A)
 0.57A 2nxeA-2ix5A:
undetectable		 2nxeA-2ix5A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12

(Homo sapiens;
Homo sapiens) 		PF00899
(ThiF)
PF08825
(E2_bind)
PF13416
(SBP_bac_8)
PF00179
(UQ_con) 		3 THR B2430
ASP C  37
SER C 127
 None
 0.79A 2nxeA-2nvuB:
5.7		 2nxeA-2nvuB:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pi5 DNA-DIRECTED RNA
POLYMERASE

(Escherichia
virus T7) 		PF00940
(RNA_pol)
PF14700
(RPOL_N) 		3 THR A 282
ASP A 147
SER A  43
 None
 0.78A 2nxeA-2pi5A:
undetectable		 2nxeA-2pi5A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmi CYCLIN-DEPENDENT
PROTEIN KINASE PHO85

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		3 THR A 237
ASP A 283
SER A 189
 None
 0.83A 2nxeA-2pmiA:
2.3		 2nxeA-2pmiA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu0 PHYTASE

(Klebsiella
pneumoniae) 		PF00328
(His_Phos_2) 		3 THR A 167
ASP A 250
SER A 252
 None
 0.84A 2nxeA-2wu0A:
undetectable		 2nxeA-2wu0A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xly CLOQ

(Streptomyces
roseochromogenus) 		PF11468
(PTase_Orf2) 		3 THR A 219
ASP A 111
SER A 109
 None
 0.65A 2nxeA-2xlyA:
undetectable		 2nxeA-2xlyA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xss CGMP-SPECIFIC 3',
5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF01590
(GAF) 		3 THR A 344
ASP A 375
SER A 377
 None
 0.69A 2nxeA-2xssA:
undetectable		 2nxeA-2xssA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xym RNA-DIRECTED RNA
POLYMERASE

(Hepacivirus C) 		PF00998
(RdRP_3) 		3 THR A 364
ASP A 318
SER A 288
 None
 0.74A 2nxeA-2xymA:
undetectable		 2nxeA-2xymA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y1s MANNAN-BINDING
LECTIN

(Microcystis
aeruginosa) 		PF08881
(CVNH) 		3 THR A  34
ASP A  99
SER A  96
 None
 0.67A 2nxeA-2y1sA:
undetectable		 2nxeA-2y1sA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3a PHOSPHATIDYLINOSITOL
-4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT BETA ISOFORM
PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA

(Mus musculus;
Mus musculus) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B)
PF00017
(SH2)
PF16454
(PI3K_P85_iSH2) 		3 THR B 462
ASP A 803
SER A 842
 None
 0.66A 2nxeA-2y3aB:
undetectable		 2nxeA-2y3aB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yp1 AROMATIC
PEROXYGENASE

(Agrocybe
aegerita) 		PF01328
(Peroxidase_2) 		3 THR A 276
ASP A 268
SER A 184
 SO4  A1331 (-4.0A)
None
None
 0.74A 2nxeA-2yp1A:
undetectable		 2nxeA-2yp1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bij UNCHARACTERIZED
PROTEIN GSU0716

(Geobacter
sulfurreducens) 		PF00656
(Peptidase_C14) 		3 THR A  52
ASP A 216
SER A 214
 None
 0.59A 2nxeA-3bijA:
undetectable		 2nxeA-3bijA:
23.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3cjt RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE

(Thermus
thermophilus) 		PF06325
(PrmA) 		3 THR A 107
ASP A 149
SER A 175
 SAH  A 258 (-2.9A)
SAH  A 258 (-2.8A)
SAH  A 258 (-2.6A)
 0.12A 2nxeA-3cjtA:
37.5		 2nxeA-3cjtA:
99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cm0 ADENYLATE KINASE

(Thermus
thermophilus) 		PF00406
(ADK) 		3 THR A 151
ASP A  83
SER A  34
 None
 0.62A 2nxeA-3cm0A:
undetectable		 2nxeA-3cm0A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eg5 PROTEIN DIAPHANOUS
HOMOLOG 1

(Mus musculus) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 THR B 297
ASP B 240
SER B 202
 None
 0.77A 2nxeA-3eg5B:
undetectable		 2nxeA-3eg5B:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN
RESPIRATORY NITRATE
REDUCTASE 1 BETA
CHAIN

(Escherichia
coli;
Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF14710
(Nitr_red_alph_N)
PF13247
(Fer4_11)
PF14711
(Nitr_red_bet_C) 		3 THR B  54
ASP A1131
SER A1151
 None
 0.72A 2nxeA-3egwB:
undetectable		 2nxeA-3egwB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh1 PROTEIN TRANSPORT
PROTEIN SEC24B

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		3 THR A 845
ASP A 854
SER A 856
 None
 0.82A 2nxeA-3eh1A:
undetectable		 2nxeA-3eh1A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejg NON-STRUCTURAL
PROTEIN 3

(Human
coronavirus
229E) 		PF01661
(Macro) 		3 THR A 152
ASP A 161
SER A 164
 None
 0.78A 2nxeA-3ejgA:
undetectable		 2nxeA-3ejgA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hs8 ADAPTOR PROTEIN
COMPLEX AP-2, ALPHA
2 SUBUNIT

(Mus musculus) 		PF02296
(Alpha_adaptin_C)
PF02883
(Alpha_adaptinC2) 		3 THR A 796
ASP A 924
SER A 922
 None
 0.83A 2nxeA-3hs8A:
undetectable		 2nxeA-3hs8A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9u V-TYPE PROTON ATPASE
CATALYTIC SUBUNIT A

(Saccharomyces
cerevisiae) 		no annotation 3 THR C 315
ASP C 355
SER C 357
 None
 0.77A 2nxeA-3j9uC:
undetectable		 2nxeA-3j9uC:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1u BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE

(Clostridium
acetobutylicum) 		PF04616
(Glyco_hydro_43) 		3 THR A  30
ASP A 135
SER A 212
 None
TRS  A 801 (-2.8A)
None
 0.84A 2nxeA-3k1uA:
undetectable		 2nxeA-3k1uA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6r SERINE RACEMASE

(Homo sapiens) 		PF00291
(PALP) 		3 THR A 235
ASP A 132
SER A 134
 None
 0.84A 2nxeA-3l6rA:
3.6		 2nxeA-3l6rA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ljp CHOLINE OXIDASE

(Arthrobacter
globiformis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		3 THR A 376
ASP A 309
SER A 384
 None
 0.86A 2nxeA-3ljpA:
3.4		 2nxeA-3ljpA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6n RNA-DEPENDENT RNA
POLYMERASE

(Enterovirus A) 		PF00680
(RdRP_1) 		3 THR A 373
ASP A 329
SER A 299
 None
BUP  A 464 ( 4.1A)
None
 0.82A 2nxeA-3n6nA:
undetectable		 2nxeA-3n6nA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naf CALCIUM-ACTIVATED
POTASSIUM CHANNEL
SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1

(Homo sapiens) 		PF03493
(BK_channel_a) 		3 THR A 939
ASP A 666
SER A 688
 None
 0.83A 2nxeA-3nafA:
6.7		 2nxeA-3nafA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nz4 PHENYLALANINE
AMMONIA-LYASE

(Taxus
canadensis) 		PF00221
(Lyase_aromatic) 		3 THR A 539
ASP A 312
SER A 310
 None
 0.71A 2nxeA-3nz4A:
undetectable		 2nxeA-3nz4A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4o INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN

(Homo sapiens) 		PF13927
(Ig_3) 		3 THR B  53
ASP B   6
SER B 103
 None
 0.86A 2nxeA-3o4oB:
undetectable		 2nxeA-3o4oB:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ob8 BETA-GALACTOSIDASE

(Kluyveromyces
lactis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N) 		3 THR A  22
ASP A 409
SER A 473
 None
 0.71A 2nxeA-3ob8A:
undetectable		 2nxeA-3ob8A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozx RNASE L INHIBITOR

(Sulfolobus
solfataricus) 		PF00005
(ABC_tran) 		3 THR A 278
ASP A 567
SER A 598
 None
 0.82A 2nxeA-3ozxA:
undetectable		 2nxeA-3ozxA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pao ADENOSINE DEAMINASE

(Pseudomonas
aeruginosa) 		PF00962
(A_deaminase) 		3 THR A  22
ASP A 168
SER A 170
 None
ADE  A 328 ( 4.2A)
None
 0.62A 2nxeA-3paoA:
undetectable		 2nxeA-3paoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfo PUTATIVE
ACETYLORNITHINE
DEACETYLASE

(Rhodopseudomonas
palustris) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 THR A 180
ASP A 385
SER A 383
 None
 0.85A 2nxeA-3pfoA:
2.7		 2nxeA-3pfoA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pjp TRANSCRIPTION
ELONGATION FACTOR
SPT6

([Candida]
glabrata) 		PF14633
(SH2_2) 		3 THR A1359
ASP A1369
SER A1371
 None
 0.85A 2nxeA-3pjpA:
undetectable		 2nxeA-3pjpA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pnd THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE

(Salmonella
enterica) 		PF02424
(ApbE) 		3 THR A  40
ASP A 298
SER A 254
 None
 0.85A 2nxeA-3pndA:
undetectable		 2nxeA-3pndA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pta DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC) 		3 THR A 885
ASP A 741
SER A 745
 None
 0.78A 2nxeA-3ptaA:
2.4		 2nxeA-3ptaA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qt4 CATHEPSIN-L-LIKE
MIDGUT CYSTEINE
PROTEINASE

(Tenebrio
molitor) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		3 THR A 127
ASP A 210
SER A 213
 None
 0.71A 2nxeA-3qt4A:
undetectable		 2nxeA-3qt4A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qw2 MYO-INOSITOL-1-PHOSP
HATE SYNTHASE (INO1)

(Archaeoglobus
fulgidus) 		PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5) 		3 THR A 294
ASP A 225
SER A 202
 None
NAD  A 396 (-4.2A)
None
 0.69A 2nxeA-3qw2A:
3.6		 2nxeA-3qw2A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slc ACETATE KINASE

(Salmonella
enterica) 		PF00871
(Acetate_kinase) 		3 THR A 385
ASP A 394
SER A 396
 None
 0.79A 2nxeA-3slcA:
undetectable		 2nxeA-3slcA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txm 26S PROTEASOME
REGULATORY COMPLEX
SUBUNIT P42B

(Drosophila
melanogaster) 		PF01399
(PCI) 		3 THR A 325
ASP A 371
SER A 366
 None
 0.65A 2nxeA-3txmA:
undetectable		 2nxeA-3txmA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubl GLUTATHIONE
TRANSFERASE

(Leptospira
interrogans) 		PF13417
(GST_N_3) 		3 THR A  76
ASP A 153
SER A 155
 SO4  A 243 (-3.8A)
None
None
 0.67A 2nxeA-3ublA:
undetectable		 2nxeA-3ublA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE

(Pachysandra
terminalis) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 THR A 153
ASP A 244
SER A 242
 None
DQR  A 800 (-3.6A)
None
 0.81A 2nxeA-3uggA:
undetectable		 2nxeA-3uggA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uo2 J-TYPE CO-CHAPERONE
JAC1, MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00226
(DnaJ)
PF07743
(HSCB_C) 		3 THR A  68
ASP A  87
SER A  94
 None
 0.78A 2nxeA-3uo2A:
undetectable		 2nxeA-3uo2A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxr PROTEASOME SUBUNIT
BETA TYPE-4
PROTEASOME SUBUNIT
BETA TYPE-5

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00227
(Proteasome)
PF00227
(Proteasome) 		3 THR L 120
ASP K   1
SER K  16
 None
 0.84A 2nxeA-3wxrL:
undetectable		 2nxeA-3wxrL:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4brz HALOALKANE
DEHALOGENASE

(Rhodobacteraceae) 		PF00561
(Abhydrolase_1) 		3 THR A  13
ASP A  71
SER A  73
 None
 0.73A 2nxeA-4brzA:
undetectable		 2nxeA-4brzA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgk SECRETED 45 KDA
PROTEIN

(Streptococcus
pneumoniae) 		PF05257
(CHAP) 		3 THR A 293
ASP A 338
SER A 382
 None
 0.80A 2nxeA-4cgkA:
undetectable		 2nxeA-4cgkA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci8 ECHINODERM
MICROTUBULE-ASSOCIAT
ED PROTEIN-LIKE 1

(Homo sapiens) 		PF00400
(WD40)
PF03451
(HELP) 		3 THR A 676
ASP A 759
SER A 785
 None
 0.71A 2nxeA-4ci8A:
undetectable		 2nxeA-4ci8A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0n A-KINASE ANCHOR
PROTEIN 13

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		3 THR B2210
ASP B2239
SER B2241
 None
 0.84A 2nxeA-4d0nB:
undetectable		 2nxeA-4d0nB:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0p COP9 SIGNALOSOME
COMPLEX SUBUNIT 4

(Homo sapiens) 		PF01399
(PCI) 		3 THR A 233
ASP A 270
SER A 313
 None
 0.79A 2nxeA-4d0pA:
undetectable		 2nxeA-4d0pA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dn7 ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Methanosarcina
mazei) 		PF01458
(UPF0051) 		3 THR A 178
ASP A  48
SER A  46
 None
 0.82A 2nxeA-4dn7A:
undetectable		 2nxeA-4dn7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4epa PESTICIN RECEPTOR

(Yersinia pestis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 THR A  43
ASP A 596
SER A 555
 None
 0.80A 2nxeA-4epaA:
undetectable		 2nxeA-4epaA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4epa PESTICIN RECEPTOR

(Yersinia pestis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 THR A 623
ASP A 230
SER A 291
 None
 0.61A 2nxeA-4epaA:
undetectable		 2nxeA-4epaA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eqq PUTATIVE HOST CELL
SURFACE-EXPOSED
LIPOPROTEIN

(Streptococcus
phage TP-J34) 		PF07553
(Lipoprotein_Ltp) 		3 THR A  63
ASP A  79
SER A  77
 None
 0.72A 2nxeA-4eqqA:
undetectable		 2nxeA-4eqqA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewp 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Micrococcus
luteus) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		3 THR A  61
ASP A 118
SER A 120
 None
 0.83A 2nxeA-4ewpA:
undetectable		 2nxeA-4ewpA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gox POLYKETIDE SYNTHASE

(Synechococcus
sp. PCC 7002) 		PF13469
(Sulfotransfer_3) 		3 THR A 196
ASP A 145
SER A 147
 None
 0.84A 2nxeA-4goxA:
undetectable		 2nxeA-4goxA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grh AMINODEOXYCHORISMATE
SYNTHASE

(Stenotrophomonas
maltophilia) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		3 THR A 192
ASP A 283
SER A 332
 None
 0.73A 2nxeA-4grhA:
undetectable		 2nxeA-4grhA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h44 APOCYTOCHROME F

(Nostoc sp. PCC
7120) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		3 THR C 201
ASP C 229
SER C 173
 None
 0.73A 2nxeA-4h44C:
undetectable		 2nxeA-4h44C:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyr GLUCARATE
DEHYDRATASE

(Acidaminococcus
intestini) 		PF13378
(MR_MLE_C) 		3 THR A 110
ASP A  93
SER A  89
 None
 0.85A 2nxeA-4hyrA:
undetectable		 2nxeA-4hyrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		3 THR A 155
ASP A 361
SER A 363
 None
 0.56A 2nxeA-4i8vA:
undetectable		 2nxeA-4i8vA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifd EXOSOME COMPLEX
COMPONENT RRP43

(Saccharomyces
cerevisiae) 		PF01138
(RNase_PH) 		3 THR C 184
ASP C 249
SER C 253
 None
 0.78A 2nxeA-4ifdC:
undetectable		 2nxeA-4ifdC:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ija XYLR PROTEIN

(Staphylococcus
aureus) 		PF00480
(ROK)
PF01047
(MarR) 		3 THR A 345
ASP A  79
SER A 136
 None
 0.81A 2nxeA-4ijaA:
undetectable		 2nxeA-4ijaA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2u ANTIBODY HEAVY CHAIN
ANTIBODY LIGHT CHAIN

(Mus musculus;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		3 THR H 182
ASP L 170
SER L 168
 None
 0.85A 2nxeA-4k2uH:
undetectable		 2nxeA-4k2uH:
19.49