SIMILAR PATTERNS OF AMINO ACIDS FOR 2NOA_A_3TCA302_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)

(Bacillus
subtilis) 		PF09195
(Endonuc-BglII) 		5 ILE A  72
GLU A  93
ALA A 127
ARG A 108
PHE A 112
 None
 1.33A 2noaA-1d2iA:
0.6		 2noaA-1d2iA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1r VIRAL IL-6

(Human
gammaherpesvirus
8) 		PF00489
(IL6) 		5 GLU B  91
LEU B 154
MET B 157
ALA B 149
ARG B 146
 None
 1.48A 2noaA-1i1rB:
undetectable		 2noaA-1i1rB:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oxx ABC TRANSPORTER, ATP
BINDING PROTEIN

(Sulfolobus
solfataricus) 		PF00005
(ABC_tran) 		5 ILE K  26
GLU K  32
LEU K 195
ALA K 208
ARG K 210
 None
None
None
None
IOD  K1917 (-4.5A)
 0.89A 2noaA-1oxxK:
0.0		 2noaA-1oxxK:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1puj CONSERVED
HYPOTHETICAL PROTEIN
YLQF

(Bacillus
subtilis) 		PF01926
(MMR_HSR1) 		5 GLU A 278
TRP A  71
LEU A  57
MET A  55
PHE A  75
 None
 1.48A 2noaA-1pujA:
undetectable		 2noaA-1pujA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qma NUCLEAR TRANSPORT
FACTOR 2

(Rattus
norvegicus) 		PF02136
(NTF2) 		5 ILE A  64
TRP A  41
LEU A 121
PHE A 119
GLN A 101
 None
 1.46A 2noaA-1qmaA:
undetectable		 2noaA-1qmaA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7e PROTEIN ARNA

(Escherichia
coli) 		PF00551
(Formyl_trans_N)
PF01370
(Epimerase)
PF02911
(Formyl_trans_C) 		5 ILE A 185
MET A   1
ALA A  96
ARG A 134
PHE A 101
 None
 1.26A 2noaA-1z7eA:
2.7		 2noaA-1z7eA:
16.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2a30 DEOXYCYTIDINE KINASE

(Homo sapiens) 		PF01712
(dNK) 		12 ILE A  30
GLU A  53
TRP A  58
LEU A  82
MET A  85
TYR A  86
PHE A  96
GLN A  97
ALA A 100
ARG A 104
ARG A 128
PHE A 137
 DCZ  A 302 ( 4.3A)
DCZ  A 302 (-3.0A)
None
DCZ  A 302 ( 4.9A)
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 ( 4.6A)
None
DCZ  A 302 (-4.1A)
DCZ  A 302 (-3.8A)
 0.48A 2noaA-2a30A:
35.3		 2noaA-2a30A:
92.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2a30 DEOXYCYTIDINE KINASE

(Homo sapiens) 		PF01712
(dNK) 		5 ILE A 200
LEU A  82
PHE A  96
GLN A  97
ARG A 128
 None
DCZ  A 302 ( 4.9A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-4.1A)
 1.12A 2noaA-2a30A:
35.3		 2noaA-2a30A:
92.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jaq DEOXYGUANOSINE
KINASE

(Mycoplasma
mycoides) 		PF01712
(dNK) 		5 TYR A  43
GLN A  54
ARG A  61
ARG A  78
PHE A  86
 None
DCP  A1202 (-2.9A)
None
DCP  A1202 (-2.8A)
DCP  A1202 (-3.6A)
 0.51A 2noaA-2jaqA:
21.8		 2noaA-2jaqA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE

(Drosophila
melanogaster) 		PF01712
(dNK) 		9 ILE A  29
TRP A  57
LEU A  66
MET A  69
TYR A  70
PHE A  80
GLN A  81
ARG A 105
PHE A 114
 TTP  A1210 (-3.9A)
None
TTP  A1210 (-4.8A)
TTP  A1210 (-4.8A)
TTP  A1210 (-4.6A)
TTP  A1210 (-4.2A)
TTP  A1210 (-3.0A)
TTP  A1210 (-3.7A)
TTP  A1210 (-3.5A)
 0.69A 2noaA-2jcsA:
25.9		 2noaA-2jcsA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nn6 POLYMYOSITIS/SCLEROD
ERMA AUTOANTIGEN 1

(Homo sapiens) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		5 GLU A 211
LEU A 138
PHE A  90
GLN A  95
ALA A  87
 None
 1.30A 2noaA-2nn6A:
undetectable		 2noaA-2nn6A:
23.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		5 GLU A  70
TRP A  75
MET A  99
PHE A 110
GLN A 111
 None
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
 1.03A 2noaA-2ocpA:
32.1		 2noaA-2ocpA:
44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		9 ILE A  47
TRP A  75
LEU A  96
MET A  99
TYR A 100
PHE A 110
GLN A 111
ARG A 142
PHE A 151
 DTP  A 301 (-3.8A)
None
DTP  A 301 (-4.6A)
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.2A)
DTP  A 301 (-3.3A)
 0.61A 2noaA-2ocpA:
32.1		 2noaA-2ocpA:
44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		6 ILE A  47
TRP A  75
LEU A  96
TYR A 100
ARG A 118
ARG A 142
 DTP  A 301 (-3.8A)
None
DTP  A 301 (-4.6A)
DTP  A 301 (-4.5A)
DTP  A 301 (-3.1A)
DTP  A 301 (-3.2A)
 0.92A 2noaA-2ocpA:
32.1		 2noaA-2ocpA:
44.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y0o PROBABLE D-LYXOSE
KETOL-ISOMERASE

(Bacillus
subtilis) 		no annotation 5 GLU A 150
LEU A  42
MET A  30
TYR A  32
GLN A  28
 ARS  A1176 (-4.1A)
None
None
None
None
 1.22A 2noaA-2y0oA:
undetectable		 2noaA-2y0oA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejv UNCHARACTERIZED
PROTEIN WITH
CYSTATIN-LIKE FOLD

(Novosphingobium
aromaticivorans) 		PF13577
(SnoaL_4) 		5 ILE A 151
MET A  28
TYR A  16
PHE A  32
ALA A  36
 UNL  A 200 (-4.4A)
UNL  A 200 (-2.7A)
UNL  A 200 (-4.3A)
None
None
 1.22A 2noaA-3ejvA:
undetectable		 2noaA-3ejvA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gme POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Escherichia
coli) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		5 GLU A 198
LEU A 505
MET A 507
PHE A 493
ALA A 526
 None
 1.50A 2noaA-3gmeA:
undetectable		 2noaA-3gmeA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwe 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE III

(Burkholderia
pseudomallei) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		5 ILE A  15
LEU A 128
TYR A 124
ARG A 184
PHE A 344
 None
 1.27A 2noaA-3gweA:
1.1		 2noaA-3gweA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpd HYDROXYETHYLTHIAZOLE
KINASE

(Pyrococcus
horikoshii) 		PF02110
(HK) 		5 ILE A 249
LEU A 200
ALA A  39
ARG A  15
ARG A  12
 None
 1.38A 2noaA-3hpdA:
2.1		 2noaA-3hpdA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ide CAPSID PROTEIN VP2

(Infectious
pancreatic
necrosis virus) 		PF01766
(Birna_VP2) 		5 ILE A 402
TRP A 415
LEU A 166
ARG A 423
PHE A 427
 None
 1.40A 2noaA-3ideA:
undetectable		 2noaA-3ideA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igq GLR4197 PROTEIN

(Gloeobacter
violaceus) 		PF02931
(Neur_chan_LBD) 		5 ILE A  76
GLU A 104
ALA A  41
ARG A  85
PHE A  78
 ACY  A 701 (-4.5A)
ACY  A 701 ( 4.8A)
None
ACY  A 701 ( 3.2A)
CL  A 901 (-4.7A)
 1.32A 2noaA-3igqA:
undetectable		 2noaA-3igqA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ipi GERANYLTRANSTRANSFER
ASE

(Methanosarcina
mazei) 		PF00348
(polyprenyl_synt) 		5 ILE A  53
LEU A 280
PHE A 203
ALA A 264
PHE A 179
 MLA  A 305 (-4.5A)
None
None
None
None
 1.15A 2noaA-3ipiA:
undetectable		 2noaA-3ipiA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nr3 PMP2 PROTEIN

(Homo sapiens) 		PF00061
(Lipocalin) 		5 ILE A 105
GLU A  73
LEU A  24
TYR A  20
ALA A  76
 PLM  A 901 ( 4.5A)
None
None
None
PLM  A 901 ( 4.0A)
 1.22A 2noaA-3nr3A:
undetectable		 2noaA-3nr3A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF04850
(Baculo_E66) 		5 ILE A 434
LEU A 485
MET A 482
PHE A 479
ALA A 477
 None
 1.34A 2noaA-3vsmA:
undetectable		 2noaA-3vsmA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF04850
(Baculo_E66) 		5 LEU A 485
MET A 482
PHE A 479
ALA A 477
ARG A 411
 None
 1.49A 2noaA-3vsmA:
undetectable		 2noaA-3vsmA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a60 FATTY ACID-BINDING
PROTEIN 9 TESTIS
LIPID-BINDING
PROTEIN, TLBP,
TESTIS-TYPE FATTY
ACID-BINDING
PROTEIN, T-FABP

(Homo sapiens) 		PF00061
(Lipocalin) 		5 ILE A 105
GLU A  73
LEU A  24
TYR A  20
ALA A  76
 None
None
None
None
EDO  A1134 ( 3.9A)
 0.92A 2noaA-4a60A:
undetectable		 2noaA-4a60A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4azp FATTY ACID-BINDING
PROTEIN, EPIDERMAL

(Mus musculus) 		PF00061
(Lipocalin) 		5 ILE A 107
GLU A  75
LEU A  26
TYR A  22
ALA A  78
 A9M  A1136 (-4.4A)
None
None
None
A9M  A1136 (-3.5A)
 1.12A 2noaA-4azpA:
undetectable		 2noaA-4azpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgu MALATE DEHYDROGENASE

(Haloferax
volcanii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 ILE A  53
LEU A  30
PHE A  32
GLN A  45
ALA A  15
 None
 1.41A 2noaA-4bguA:
2.2		 2noaA-4bguA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gp1 POLYPRENYL
SYNTHETASE

(Pyrobaculum
calidifontis) 		PF00348
(polyprenyl_synt) 		5 GLU A  18
LEU A  25
TYR A 116
ALA A  20
ARG A  47
 None
 1.19A 2noaA-4gp1A:
undetectable		 2noaA-4gp1A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i5u CHIMERIC CEL6A

(Chaetomium
thermophilum;
Humicola
insolens;
Trichoderma
reesei) 		PF01341
(Glyco_hydro_6) 		5 ILE A 247
LEU A 297
PHE A 343
ALA A 345
PHE A 284
 None
 1.39A 2noaA-4i5uA:
undetectable		 2noaA-4i5uA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4io6 AVGLUR1 LIGAND
BINDING DOMAIN

(Adineta vaga) 		PF00497
(SBP_bac_3) 		5 ILE A 209
LEU A   5
MET A  52
PHE A  54
ALA A  56
 None
 1.36A 2noaA-4io6A:
undetectable		 2noaA-4io6A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmh EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT OMCA

(Shewanella
oneidensis) 		no annotation 5 ILE A 225
GLU A 248
PHE A 269
ALA A 251
ARG A 189
 None
None
HEC  A 803 ( 3.9A)
HEC  A 803 ( 4.4A)
None
 1.41A 2noaA-4lmhA:
undetectable		 2noaA-4lmhA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmg STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00565
(SNase) 		5 ILE A 198
LEU A 218
ALA A  60
ARG A  83
PHE A  80
 None
 1.22A 2noaA-4qmgA:
undetectable		 2noaA-4qmgA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u06 LIC10831

(Leptospira
interrogans) 		PF12799
(LRR_4)
PF13855
(LRR_8) 		5 ILE A 341
GLU A 361
LEU A 352
PHE A 376
ARG A 364
 None
 1.22A 2noaA-4u06A:
undetectable		 2noaA-4u06A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a65 THIAMINE
TRIPHOSPHATASE

(Mus musculus) 		PF01928
(CYTH) 		5 TYR A  39
PHE A 121
ALA A 149
ARG A 125
PHE A  35
 None
None
None
PO4  A1001 (-3.0A)
None
 1.20A 2noaA-5a65A:
undetectable		 2noaA-5a65A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c78 ATP-DRIVEN FLIPPASE
PGLK

(Campylobacter
jejuni) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		5 ILE A 523
LEU A 508
MET A 536
ALA A 540
ARG A 542
 None
 1.42A 2noaA-5c78A:
undetectable		 2noaA-5c78A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5liq NICKING ENDONUCLEASE
N.BSPD6I

(Bacillus sp.
(in: Bacteria)) 		PF09491
(RE_AlwI) 		5 LEU A 144
PHE A 140
GLN A 168
ALA A 163
ARG A 203
 None
 1.49A 2noaA-5liqA:
undetectable		 2noaA-5liqA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnk MITOCHONDRIAL
COMPLEX I, 42 KDA
SUBUNIT

(Ovis aries) 		PF00420
(Oxidored_q2) 		5 LEU k  79
TYR k  83
GLN k  97
ARG k 104
ARG k 126
 None
 1.35A 2noaA-5lnkk:
16.0		 2noaA-5lnkk:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t79 ALDO-KETO REDUCTASE,
OXIDOREDUCTASE

(Salmonella
enterica) 		PF00248
(Aldo_ket_red) 		5 ILE A 327
GLU A 268
LEU A 277
MET A 280
ALA A 271
 None
 1.13A 2noaA-5t79A:
undetectable		 2noaA-5t79A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		5 ILE A 532
LEU A 632
PHE A 604
ALA A 562
ARG A 563
 None
 1.30A 2noaA-5ux5A:
undetectable		 2noaA-5ux5A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyk PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		no annotation 5 ILE E  81
PHE E 112
GLN E 116
ARG E  72
PHE E  73
 None
 1.21A 2noaA-5xykE:
undetectable		 2noaA-5xykE:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fht BACTERIOPHYTOCHROME,
ADENYLATE CYCLASE

(Deinococcus
radiodurans;
Synechocystis
sp. PCC 6803) 		no annotation 5 ILE A 595
GLU A 676
LEU A 550
TYR A 572
GLN A 620
 None
 1.28A 2noaA-6fhtA:
undetectable		 2noaA-6fhtA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 6 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.99A 2noaA-6g2jO:
undetectable		 2noaA-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 6 ILE O  31
GLU O  53
LEU O  79
TYR O  83
GLN O  97
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
 1.01A 2noaA-6g2jO:
undetectable		 2noaA-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 5 ILE O  31
GLU O  53
TYR O  83
ARG O 104
ARG O 126
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
 1.08A 2noaA-6g2jO:
undetectable		 2noaA-6g2jO:
13.93