SIMILAR PATTERNS OF AMINO ACIDS FOR 2NO0_A_GEOA302_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h6u INTERNALIN H

(Listeria
monocytogenes) 		PF08191
(LRR_adjacent)
PF12354
(Internalin_N)
PF12799
(LRR_4)
PF13516
(LRR_6) 		5 ILE A 242
VAL A 235
LEU A 248
PHE A 326
PHE A 333
 None
 1.40A 2no0A-1h6uA:
0.0		 2no0A-1h6uA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofe FERREDOXIN-DEPENDENT
GLUTAMATE SYNTHASE 2

(Synechocystis
sp. PCC 6803) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		5 ILE A 150
GLU A 143
LEU A 102
ARG A 146
GLU A 100
 None
 1.28A 2no0A-1ofeA:
0.2		 2no0A-1ofeA:
11.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2a30 DEOXYCYTIDINE KINASE

(Homo sapiens) 		PF01712
(dNK) 		12 ILE A  30
GLU A  53
VAL A  55
TRP A  58
LEU A  82
MET A  85
TYR A  86
PHE A  96
GLN A  97
ARG A 128
PHE A 137
GLU A 197
 DCZ  A 302 ( 4.3A)
DCZ  A 302 (-3.0A)
None
None
DCZ  A 302 ( 4.9A)
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-4.1A)
DCZ  A 302 (-3.8A)
DCZ  A 302 (-3.5A)
 0.48A 2no0A-2a30A:
35.8		 2no0A-2a30A:
92.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2a30 DEOXYCYTIDINE KINASE

(Homo sapiens) 		PF01712
(dNK) 		7 VAL A  55
TRP A  58
LEU A  82
MET A  85
PHE A  96
GLN A  97
GLU A 196
 None
None
DCZ  A 302 ( 4.9A)
DCZ  A 302 ( 4.3A)
DCZ  A 302 (-4.6A)
DCZ  A 302 (-3.2A)
None
 1.48A 2no0A-2a30A:
35.8		 2no0A-2a30A:
92.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN

(Bacillus
halodurans) 		PF01923
(Cob_adeno_trans) 		5 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.35A 2no0A-2ah6A:
undetectable		 2no0A-2ah6A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2i GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Synechococcus
sp.) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		5 ILE A  67
VAL A  31
TRP A  21
LEU A  18
PHE A  22
 None
 1.48A 2no0A-2d2iA:
2.9		 2no0A-2d2iA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icu HYPOTHETICAL PROTEIN
YEDK

(Escherichia
coli) 		PF02586
(SRAP) 		5 ILE A 154
VAL A  66
LEU A  53
GLN A  14
PHE A  12
 None
 1.47A 2no0A-2icuA:
0.0		 2no0A-2icuA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jaq DEOXYGUANOSINE
KINASE

(Mycoplasma
mycoides) 		PF01712
(dNK) 		6 VAL A  33
TYR A  43
GLN A  54
ARG A  78
PHE A  86
GLU A 150
 DCP  A1202 (-4.6A)
None
DCP  A1202 (-2.9A)
DCP  A1202 (-2.8A)
DCP  A1202 (-3.6A)
DCP  A1202 (-3.5A)
 0.57A 2no0A-2jaqA:
22.5		 2no0A-2jaqA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE

(Drosophila
melanogaster) 		PF01712
(dNK) 		9 ILE A  29
VAL A  54
TRP A  57
LEU A  66
MET A  69
TYR A  70
PHE A  80
PHE A 114
GLU A 172
 TTP  A1210 (-3.9A)
TTP  A1210 (-4.5A)
None
TTP  A1210 (-4.8A)
TTP  A1210 (-4.8A)
TTP  A1210 (-4.6A)
TTP  A1210 (-4.2A)
TTP  A1210 (-3.5A)
TTP  A1210 (-3.6A)
 0.69A 2no0A-2jcsA:
26.1		 2no0A-2jcsA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE

(Drosophila
melanogaster) 		PF01712
(dNK) 		9 ILE A  29
VAL A  54
TRP A  57
LEU A  66
TYR A  70
PHE A  80
GLN A  81
PHE A 114
GLU A 172
 TTP  A1210 (-3.9A)
TTP  A1210 (-4.5A)
None
TTP  A1210 (-4.8A)
TTP  A1210 (-4.6A)
TTP  A1210 (-4.2A)
TTP  A1210 (-3.0A)
TTP  A1210 (-3.5A)
TTP  A1210 (-3.6A)
 0.56A 2no0A-2jcsA:
26.1		 2no0A-2jcsA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE

(Drosophila
melanogaster) 		PF01712
(dNK) 		7 ILE A  29
VAL A  54
TRP A  57
PHE A  80
GLN A  81
ARG A 105
PHE A 114
 TTP  A1210 (-3.9A)
TTP  A1210 (-4.5A)
None
TTP  A1210 (-4.2A)
TTP  A1210 (-3.0A)
TTP  A1210 (-3.7A)
TTP  A1210 (-3.5A)
 0.87A 2no0A-2jcsA:
26.1		 2no0A-2jcsA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE

(Drosophila
melanogaster) 		PF01712
(dNK) 		5 VAL A  54
TRP A  57
MET A  69
PHE A  80
GLU A 171
 TTP  A1210 (-4.5A)
None
TTP  A1210 (-4.8A)
TTP  A1210 (-4.2A)
None
 1.41A 2no0A-2jcsA:
26.1		 2no0A-2jcsA:
28.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		6 GLU A  70
VAL A  72
TRP A  75
MET A  99
PHE A 110
GLN A 111
 None
DTP  A 301 (-4.1A)
None
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
 1.18A 2no0A-2ocpA:
32.3		 2no0A-2ocpA:
44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		11 ILE A  47
VAL A  72
TRP A  75
LEU A  96
MET A  99
TYR A 100
PHE A 110
GLN A 111
ARG A 142
PHE A 151
GLU A 211
 DTP  A 301 (-3.8A)
DTP  A 301 (-4.1A)
None
DTP  A 301 (-4.6A)
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-4.2A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.2A)
DTP  A 301 (-3.3A)
DTP  A 301 (-3.5A)
 0.69A 2no0A-2ocpA:
32.3		 2no0A-2ocpA:
44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		5 VAL A  72
LEU A  96
MET A  99
TYR A 100
ARG A 118
 DTP  A 301 (-4.1A)
DTP  A 301 (-4.6A)
DTP  A 301 ( 3.9A)
DTP  A 301 (-4.5A)
DTP  A 301 (-3.1A)
 1.45A 2no0A-2ocpA:
32.3		 2no0A-2ocpA:
44.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqb HISTONE-ARGININE
METHYLTRANSFERASE
CARM1

(Rattus
norvegicus) 		PF11531
(CARM1) 		5 ILE A 101
VAL A  61
LEU A  59
PHE A 112
PHE A  99
 None
 1.28A 2no0A-2oqbA:
undetectable		 2no0A-2oqbA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qw5 XYLOSE
ISOMERASE-LIKE TIM
BARREL

(Trichormus
variabilis) 		PF01261
(AP_endonuc_2) 		5 ILE A 184
GLU A 280
LEU A 292
PHE A 288
GLU A 188
 XLS  A 401 ( 4.3A)
ZN  A 400 (-2.5A)
None
None
XLS  A 401 (-3.2A)
 1.33A 2no0A-2qw5A:
undetectable		 2no0A-2qw5A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmf BETA-MANNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2) 		5 VAL A 141
LEU A 215
MET A  34
PHE A 217
GLN A 101
 None
 1.32A 2no0A-2vmfA:
undetectable		 2no0A-2vmfA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr5 GLYCOGEN OPERON
PROTEIN GLGX

(Sulfolobus
solfataricus) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		5 VAL A 219
LEU A 211
MET A 207
TYR A 210
PHE A 566
 None
 1.49A 2no0A-2vr5A:
undetectable		 2no0A-2vr5A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y0o PROBABLE D-LYXOSE
KETOL-ISOMERASE

(Bacillus
subtilis) 		no annotation 5 GLU A 150
LEU A  42
MET A  30
TYR A  32
GLN A  28
 ARS  A1176 (-4.1A)
None
None
None
None
 1.18A 2no0A-2y0oA:
undetectable		 2no0A-2y0oA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkg E3 UBIQUITIN-PROTEIN
LIGASE UHRF1

(Mus musculus) 		PF02182
(SAD_SRA) 		5 ILE A 454
VAL A 537
LEU A 584
TYR A 483
PHE A 481
 None
 1.49A 2no0A-2zkgA:
undetectable		 2no0A-2zkgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4b ALGK

(Pseudomonas
fluorescens) 		no annotation 5 VAL A 222
LEU A  32
TYR A  34
GLN A 214
GLU A 181
 None
 1.49A 2no0A-3e4bA:
undetectable		 2no0A-3e4bA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f8h PUTATIVE POLYKETIDE
CYCLASE

(Ruegeria sp.
TM1040) 		PF12680
(SnoaL_2) 		5 VAL A  28
LEU A  24
MET A  20
TYR A   8
PHE A  47
 None
None
MRD  A 135 ( 3.9A)
None
None
 1.45A 2no0A-3f8hA:
undetectable		 2no0A-3f8hA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus cereus) 		PF01923
(Cob_adeno_trans) 		5 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
 None
 1.30A 2no0A-3ke5A:
undetectable		 2no0A-3ke5A:
27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tac LIPRIN-ALPHA-2

(Homo sapiens) 		PF00536
(SAM_1)
PF07647
(SAM_2) 		5 ILE B 939
TRP B 906
LEU B 907
MET B 913
TYR B 917
 None
 1.12A 2no0A-3tacB:
undetectable		 2no0A-3tacB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tac LIPRIN-ALPHA-2

(Homo sapiens) 		PF00536
(SAM_1)
PF07647
(SAM_2) 		5 ILE B 943
VAL B 903
TRP B 906
LEU B 907
MET B 913
 None
 1.19A 2no0A-3tacB:
undetectable		 2no0A-3tacB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tad LIPRIN-ALPHA-2

(Homo sapiens) 		PF00536
(SAM_1)
PF07647
(SAM_2) 		5 ILE A 939
TRP A 906
LEU A 907
MET A 913
TYR A 917
 None
 1.11A 2no0A-3tadA:
undetectable		 2no0A-3tadA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tad LIPRIN-ALPHA-2

(Homo sapiens) 		PF00536
(SAM_1)
PF07647
(SAM_2) 		5 ILE A 943
VAL A 903
TRP A 906
LEU A 907
MET A 913
 None
 1.31A 2no0A-3tadA:
undetectable		 2no0A-3tadA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ip3 ORF169B

(Shigella
flexneri) 		no annotation 6 ILE A 107
GLU A 113
VAL A 181
LEU A 169
PHE A 167
ARG A 121
 None
 1.41A 2no0A-4ip3A:
undetectable		 2no0A-4ip3A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m9a ACYL-COA
DEHYDROGENASE

(Burkholderia
thailandensis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		5 ILE A  76
TRP A  31
LEU A  37
GLN A  44
PHE A  19
 None
 1.40A 2no0A-4m9aA:
undetectable		 2no0A-4m9aA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u09 LIC12759

(Leptospira
interrogans) 		PF13855
(LRR_8) 		5 ILE A 382
GLU A 402
LEU A 393
PHE A 417
ARG A 405
 None
 1.09A 2no0A-4u09A:
undetectable		 2no0A-4u09A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7l CAS6B

(Methanococcus
maripaludis) 		PF17262
(DUF5328) 		5 ILE A  79
LEU A  85
TYR A  10
PHE A  54
GLU A  82
 None
 1.28A 2no0A-4z7lA:
undetectable		 2no0A-4z7lA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aff SYMPORTIN 1

(Chaetomium
thermophilum) 		no annotation 5 ILE A 201
VAL A 131
LEU A 135
PHE A 142
GLN A 150
 None
 1.33A 2no0A-5affA:
undetectable		 2no0A-5affA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7e RNA 2',3'-CYCLIC
PHOSPHODIESTERASE

(Deinococcus
radiodurans) 		PF02834
(LigT_PEase) 		5 ILE A 146
VAL A  90
LEU A 190
TYR A  44
PHE A 208
 None
 1.47A 2no0A-5h7eA:
undetectable		 2no0A-5h7eA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h80 CARBOXYLASE

(Deinococcus
radiodurans) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		5 GLU A 299
VAL A 307
LEU A 291
TYR A  81
ARG A 373
 EDO  A 505 ( 4.2A)
None
None
None
EDO  A 505 (-4.1A)
 1.40A 2no0A-5h80A:
undetectable		 2no0A-5h80A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ks8 PYRUVATE CARBOXYLASE
SUBUNIT ALPHA

(Methylobacillus
flagellatus) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		5 GLU A 300
VAL A 308
LEU A 292
TYR A  81
ARG A 366
 None
 1.42A 2no0A-5ks8A:
undetectable		 2no0A-5ks8A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyk PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		no annotation 5 ILE E  81
PHE E 112
GLN E 116
ARG E  72
PHE E  73
 None
 1.22A 2no0A-5xykE:
undetectable		 2no0A-5xykE:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y58 ATP-DEPENDENT DNA
HELICASE II SUBUNIT
1

(Saccharomyces
cerevisiae) 		no annotation 5 GLU A  30
LEU A  69
ARG A 167
PHE A 169
GLU A 262
 None
 1.13A 2no0A-5y58A:
1.5		 2no0A-5y58A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zl9 CHITINASE AB

(Serratia
marcescens) 		no annotation 5 ILE A 460
VAL A 453
LEU A 514
TYR A 505
GLN A 494
 None
 0.98A 2no0A-5zl9A:
undetectable		 2no0A-5zl9A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bbp CYTOHESIN-3,ADP-RIBO
SYLATION FACTOR 6

(Homo sapiens;
Mus musculus) 		no annotation 5 GLU A 311
LEU A 388
TYR A 429
PHE A 384
GLU A 448
 None
 1.48A 2no0A-6bbpA:
5.7		 2no0A-6bbpA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 6 ILE O  31
GLU O  53
LEU O  79
GLN O  97
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.94A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 6 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.97A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 6 ILE O  31
LEU O  79
GLN O  97
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 1.01A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 6 ILE O  31
LEU O  79
TYR O  83
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 0.86A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93