SIMILAR PATTERNS OF AMINO ACIDS FOR 2NNJ_A_225A501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8z TUBBY PROTEIN

(Mus musculus) 		PF01167
(Tub) 		5 ALA A 490
VAL A 386
VAL A 388
PRO A 389
VAL A 369
 None
 0.94A 2nnjA-1c8zA:
undetectable		 2nnjA-1c8zA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxy D-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Lactobacillus
casei) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		5 ALA A 109
THR A 113
VAL A 148
VAL A 150
ILE A 201
 None
 1.03A 2nnjA-1dxyA:
undetectable		 2nnjA-1dxyA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxy D-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Lactobacillus
casei) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		5 ALA A 109
VAL A 148
VAL A 150
ILE A 201
VAL A 200
 None
 1.06A 2nnjA-1dxyA:
undetectable		 2nnjA-1dxyA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanosarcina
barkeri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		5 ILE B2111
VAL B2086
ALA B2134
VAL B2172
ILE B2050
 None
 1.02A 2nnjA-1e6yB:
0.7		 2nnjA-1e6yB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jye LACTOSE OPERON
REPRESSOR

(Escherichia
coli) 		PF13377
(Peripla_BP_3) 		5 ILE A 124
ALA A  67
VAL A 119
PRO A 144
ILE A  64
 None
 1.01A 2nnjA-1jyeA:
undetectable		 2nnjA-1jyeA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kuu CONSERVED PROTEIN

(Methanothermobacter) 		PF07826
(IMP_cyclohyd) 		5 ILE A 170
ALA A 185
THR A  32
ILE A  62
VAL A  39
 None
 1.08A 2nnjA-1kuuA:
undetectable		 2nnjA-1kuuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lia R-PHYCOERYTHRIN

(Polysiphonia
urceolata) 		PF00502
(Phycobilisome) 		5 LEU B  92
VAL B 162
ALA B 163
VAL B 170
VAL B 169
 None
 1.06A 2nnjA-1liaB:
undetectable		 2nnjA-1liaB:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p3w CYSTEINE DESULFURASE

(Escherichia
coli) 		no annotation 5 ILE B  69
LEU B 199
ALA B 215
VAL B 185
VAL B  62
 None
 1.00A 2nnjA-1p3wB:
undetectable		 2nnjA-1p3wB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf7 PROTEIN (CATALASE
HPII)

(Escherichia
coli) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		5 ILE A 675
ALA A 681
VAL A 665
VAL A 667
PRO A 668
 None
 0.86A 2nnjA-1qf7A:
undetectable		 2nnjA-1qf7A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sqj OLIGOXYLOGLUCAN
REDUCING-END-SPECIFI
C CELLOBIOHYDROLASE

(Geotrichum sp.
M128) 		PF15899
(BNR_6) 		5 ALA A 607
VAL A 648
VAL A 650
PRO A 651
VAL A 640
 None
 0.94A 2nnjA-1sqjA:
0.0		 2nnjA-1sqjA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tzb GLUCOSE-6-PHOSPHATE
ISOMERASE,
CONJECTURAL

(Pyrobaculum
aerophilum) 		PF10432
(bact-PGI_C) 		5 ILE A 112
LEU A  82
VAL A 148
ALA A 145
VAL A  68
 None
 1.05A 2nnjA-1tzbA:
0.0		 2nnjA-1tzbA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukm EMS16 A CHAIN

(Echis
multisquamatus) 		PF00059
(Lectin_C) 		5 ALA A  54
VAL A 128
VAL A  68
ILE A  70
VAL A  42
 None
 1.04A 2nnjA-1ukmA:
undetectable		 2nnjA-1ukmA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1va8 MAGUK P55 SUBFAMILY
MEMBER 5

(Mus musculus) 		PF00595
(PDZ) 		5 ILE A  55
ALA A  41
VAL A  73
ILE A  51
VAL A  50
 None
 1.05A 2nnjA-1va8A:
undetectable		 2nnjA-1va8A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdi HYPOTHETICAL PROTEIN
TT0907

(Thermus
thermophilus) 		PF02547
(Queuosine_synth) 		5 LEU A 204
VAL A 256
ALA A 255
VAL A 243
VAL A 239
 None
 1.09A 2nnjA-1wdiA:
undetectable		 2nnjA-1wdiA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmp PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE

(Bacillus
anthracis) 		PF00731
(AIRC) 		5 ALA A 124
VAL A   5
VAL A   7
ILE A  61
VAL A  60
 None
 1.03A 2nnjA-1xmpA:
undetectable		 2nnjA-1xmpA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y17 ANTICOAGULANT
PROTEIN A

(Deinagkistrodon
acutus) 		PF00059
(Lectin_C) 		5 ALA A  52
VAL A 126
VAL A  66
ILE A  68
VAL A  40
 None
 1.09A 2nnjA-1y17A:
undetectable		 2nnjA-1y17A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y56 SARCOSINE OXIDASE

(Pyrococcus
horikoshii) 		PF01266
(DAO) 		5 VAL B 348
ALA B 349
THR B 353
VAL B  31
ILE B 196
 None
 1.07A 2nnjA-1y56B:
undetectable		 2nnjA-1y56B:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yif BETA-1,4-XYLOSIDASE

(Bacillus
subtilis) 		PF04616
(Glyco_hydro_43) 		5 ILE A  26
ALA A 262
VAL A   7
ILE A   3
VAL A 313
 None
 1.07A 2nnjA-1yifA:
undetectable		 2nnjA-1yifA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE

(Archaeoglobus
fulgidus) 		PF05362
(Lon_C) 		5 ILE A 514
VAL A 518
ALA A 517
VAL A 595
ILE A 592
 None
 1.01A 2nnjA-1z0vA:
undetectable		 2nnjA-1z0vA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bhn XPF ENDONUCLEASE

(Aeropyrum
pernix) 		PF02732
(ERCC4)
PF14520
(HHH_5) 		5 THR A 130
VAL A  32
PRO A  33
ILE A 140
VAL A 139
 None
 1.04A 2nnjA-2bhnA:
undetectable		 2nnjA-2bhnA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2g THREONINE SYNTHASE

(Arabidopsis
thaliana) 		PF00291
(PALP) 		5 ALA A 274
VAL A 290
VAL A 292
PRO A 293
VAL A 428
 None
 1.00A 2nnjA-2c2gA:
undetectable		 2nnjA-2c2gA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ctj VIGILIN

(Homo sapiens) 		PF00013
(KH_1) 		5 ILE A  42
ALA A  75
VAL A  63
ILE A  23
VAL A  21
 None
 1.03A 2nnjA-2ctjA:
undetectable		 2nnjA-2ctjA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5y ATP SYNTHASE EPSILON
CHAIN

(Bacillus sp.
PS3) 		PF00401
(ATP-synt_DE)
PF02823
(ATP-synt_DE_N) 		5 ILE A  77
VAL A  25
ALA A  50
VAL A  20
VAL A   6
 None
 0.90A 2nnjA-2e5yA:
undetectable		 2nnjA-2e5yA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5y ATP SYNTHASE EPSILON
CHAIN

(Bacillus sp.
PS3) 		PF00401
(ATP-synt_DE)
PF02823
(ATP-synt_DE_N) 		5 ILE A  77
VAL A  25
VAL A  20
VAL A   6
ILE A   4
 None
 0.98A 2nnjA-2e5yA:
undetectable		 2nnjA-2e5yA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2epk N-ACETYL-BETA-D-GLUC
OSAMINIDASE

(Streptococcus
gordonii) 		PF00728
(Glyco_hydro_20) 		5 ILE X 618
ALA X 612
THR X 610
PRO X 453
ILE X 459
 None
 0.93A 2nnjA-2epkX:
undetectable		 2nnjA-2epkX:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmt METHIONYL-TRNA FMET
FORMYLTRANSFERASE

(Escherichia
coli) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		5 ILE A 240
LEU A 299
VAL A 245
VAL A 274
ILE A 272
 None
 1.03A 2nnjA-2fmtA:
undetectable		 2nnjA-2fmtA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fy2 CHOLINE
O-ACETYLTRANSFERASE

(Homo sapiens) 		PF00755
(Carn_acyltransf) 		5 ILE A 575
LEU A 572
ALA A 562
VAL A 593
ILE A 571
 None
 1.06A 2nnjA-2fy2A:
undetectable		 2nnjA-2fy2A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4o 3-ISOPROPYLMALATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00180
(Iso_dh) 		5 LEU A   3
ALA A 292
VAL A  26
VAL A  22
VAL A  27
 None
 1.06A 2nnjA-2g4oA:
undetectable		 2nnjA-2g4oA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ha9 UPF0210 PROTEIN
SP0239

(Streptococcus
pneumoniae) 		PF05167
(DUF711) 		5 ILE A 430
ALA A 380
VAL A 184
ILE A 397
VAL A 395
 None
 1.02A 2nnjA-2ha9A:
undetectable		 2nnjA-2ha9A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iye COPPER-TRANSPORTING
ATPASE

(Sulfolobus
solfataricus) 		PF00702
(Hydrolase) 		5 ILE A 467
VAL A 457
ALA A 442
VAL A 470
VAL A 481
 None
 0.85A 2nnjA-2iyeA:
undetectable		 2nnjA-2iyeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p6d DIPHTHINE SYNTHASE

(Pyrococcus
horikoshii) 		PF00590
(TP_methylase) 		5 ALA A 181
VAL A 203
VAL A 205
ILE A 237
VAL A 238
 None
 1.08A 2nnjA-2p6dA:
undetectable		 2nnjA-2p6dA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po3 4-DEHYDRASE

(Streptomyces
venezuelae) 		PF01041
(DegT_DnrJ_EryC1) 		5 ILE A1372
VAL A1375
ALA A1376
VAL A1285
VAL A1301
 None
 0.91A 2nnjA-2po3A:
undetectable		 2nnjA-2po3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rmn TUMOR PROTEIN 63

(Homo sapiens) 		PF00870
(P53) 		5 LEU A 288
ALA A 188
VAL A 263
ILE A 174
VAL A 140
 None
 0.95A 2nnjA-2rmnA:
undetectable		 2nnjA-2rmnA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4n MULTIFUNCTIONAL
PROTEIN SUR E

(Salmonella
enterica) 		PF01975
(SurE) 		5 ALA A 140
VAL A 158
VAL A 160
PRO A 161
VAL A 224
 None
 1.04A 2nnjA-2v4nA:
undetectable		 2nnjA-2v4nA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9h OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET

(Escherichia
coli) 		PF07244
(POTRA) 		5 ILE A  29
VAL A  39
VAL A  75
VAL A  77
VAL A  88
 None
 0.94A 2nnjA-2v9hA:
undetectable		 2nnjA-2v9hA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wpm COAGULATION FACTOR
IXA HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 ILE S 123
LEU S 105
VAL S  47
VAL S 231
ILE S 103
 None
 0.98A 2nnjA-2wpmS:
undetectable		 2nnjA-2wpmS:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x49 INVASION PROTEIN
INVA

(Salmonella
enterica) 		PF00771
(FHIPEP) 		5 LEU A 413
VAL A 398
ALA A 380
ILE A 411
VAL A 366
 None
 1.06A 2nnjA-2x49A:
undetectable		 2nnjA-2x49A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Corynebacterium
glutamicum) 		PF00155
(Aminotran_1_2) 		5 ILE A 101
LEU A  92
ALA A  95
VAL A 250
ILE A 247
 None
 1.06A 2nnjA-3cq5A:
undetectable		 2nnjA-3cq5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3u 4-HYDROXYBUTYRATE
COA-TRANSFERASE

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		5 ILE A 178
ALA A  17
VAL A 119
VAL A 121
VAL A 151
 None
 1.01A 2nnjA-3d3uA:
undetectable		 2nnjA-3d3uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwb ENDOTHELIN-CONVERTIN
G ENZYME 1

(Homo sapiens) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		5 ILE A 346
ALA A 343
VAL A 369
ILE A 367
VAL A 334
 None
 1.06A 2nnjA-3dwbA:
undetectable		 2nnjA-3dwbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwz BETA-LACTAMASE

(Mycobacterium
tuberculosis) 		PF13354
(Beta-lactamase2) 		5 ALA A 303
VAL A  61
VAL A  63
PRO A  64
VAL A 277
 None
 1.08A 2nnjA-3dwzA:
undetectable		 2nnjA-3dwzA:
19.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e4e CYTOCHROME P450 2E1

(Homo sapiens) 		PF00067
(p450) 		5 ILE A 115
ALA A 299
THR A 303
VAL A 364
PRO A 369
 HEM  A 500 (-4.0A)
HEM  A 500 ( 3.3A)
4PZ  A 501 ( 2.8A)
HEM  A 500 ( 4.4A)
None
 0.69A 2nnjA-3e4eA:
52.3		 2nnjA-3e4eA:
59.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e4e CYTOCHROME P450 2E1

(Homo sapiens) 		PF00067
(p450) 		5 ILE A 115
LEU A 210
ALA A 299
THR A 303
PRO A 369
 HEM  A 500 (-4.0A)
None
HEM  A 500 ( 3.3A)
4PZ  A 501 ( 2.8A)
None
 1.01A 2nnjA-3e4eA:
52.3		 2nnjA-3e4eA:
59.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g6e 50S RIBOSOMAL
PROTEIN L13P

(Haloarcula
marismortui) 		PF00572
(Ribosomal_L13) 		5 VAL J  22
ALA J  23
VAL J 101
VAL J 103
VAL J  36
 None
None
None
G  02815 ( 4.2A)
None
 1.01A 2nnjA-3g6eJ:
undetectable		 2nnjA-3g6eJ:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06

(Sarcoptes
scabiei) 		PF00089
(Trypsin) 		5 ILE A  74
ALA A  40
VAL A  20
PRO A  48
VAL A  18
 None
 1.03A 2nnjA-3h7tA:
undetectable		 2nnjA-3h7tA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igf ALL4481 PROTEIN

(Nostoc sp. PCC
7120) 		PF02374
(ArsA_ATPase) 		5 ALA A 223
VAL A 268
VAL A 270
ILE A 249
VAL A 248
 None
 1.03A 2nnjA-3igfA:
undetectable		 2nnjA-3igfA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l84 TRANSKETOLASE

(Campylobacter
jejuni) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		5 ILE A 397
LEU A 172
ALA A 121
VAL A  62
ILE A 146
 None
 0.98A 2nnjA-3l84A:
undetectable		 2nnjA-3l84A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lp6 PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CATALYTIC SUBUNIT

(Mycobacterium
tuberculosis) 		PF00731
(AIRC) 		5 ALA A 127
VAL A  10
VAL A  12
ILE A  66
VAL A  65
 None
 1.06A 2nnjA-3lp6A:
undetectable		 2nnjA-3lp6A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lw9 INVASION PROTEIN
INVA

(Salmonella
enterica) 		PF00771
(FHIPEP) 		5 LEU A 413
VAL A 398
ALA A 380
ILE A 411
VAL A 366
 None
 1.05A 2nnjA-3lw9A:
undetectable		 2nnjA-3lw9A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgz 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF00926
(DHBP_synthase) 		5 LEU A  34
ALA A  41
VAL A 128
VAL A  59
PRO A  60
 None
 1.02A 2nnjA-3mgzA:
undetectable		 2nnjA-3mgzA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwy URIDYLATE KINASE

(Mycobacterium
tuberculosis) 		PF00696
(AA_kinase) 		5 VAL A  57
ALA A  58
VAL A  65
VAL A 151
VAL A  64
 None
 1.00A 2nnjA-3nwyA:
undetectable		 2nnjA-3nwyA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opq PHOSPHORIBOSYLAMINOI
MIDAZOLE
CARBOXYLASE,CATALYTI
C SUBUNIT

(Francisella
tularensis) 		PF00731
(AIRC) 		5 ALA A 124
VAL A   5
VAL A   7
ILE A  61
VAL A  60
 None
 1.08A 2nnjA-3opqA:
undetectable		 2nnjA-3opqA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ot1 4-METHYL-5(B-HYDROXY
ETHYL)-THIAZOLE
MONOPHOSPHATE
BIOSYNTHESIS ENZYME

(Vibrio cholerae) 		PF01965
(DJ-1_PfpI) 		5 LEU B 103
ALA B 167
VAL B  36
VAL B  11
PRO B  12
 None
 0.99A 2nnjA-3ot1B:
undetectable		 2nnjA-3ot1B:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pen TRANSLATION
INITIATION FACTOR 2
SUBUNIT GAMMA

(Sulfolobus
solfataricus) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF09173
(eIF2_C) 		5 ILE A 191
ALA A  28
VAL A 117
ILE A 115
VAL A  14
 None
 1.01A 2nnjA-3penA:
undetectable		 2nnjA-3penA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		5 ILE A  83
ALA A  73
VAL A  59
VAL A  33
VAL A  61
 None
 1.06A 2nnjA-3qivA:
undetectable		 2nnjA-3qivA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qxz ENOYL-COA
HYDRATASE/ISOMERASE

(Mycobacteroides
abscessus) 		PF00378
(ECH_1) 		5 ALA A 189
VAL A  13
VAL A  15
ILE A  51
VAL A  50
 None
 1.03A 2nnjA-3qxzA:
undetectable		 2nnjA-3qxzA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyn TUMOR PROTEIN 63

(Homo sapiens) 		PF00870
(P53) 		5 LEU A 288
ALA A 188
VAL A 263
ILE A 174
VAL A 140
 None
 0.97A 2nnjA-3qynA:
undetectable		 2nnjA-3qynA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfo PUTATIVE
3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE

(Sinorhizobium
meliloti) 		PF00106
(adh_short) 		5 LEU A  85
VAL A  68
ALA A  69
VAL A  76
ILE A  82
 None
 0.94A 2nnjA-3tfoA:
undetectable		 2nnjA-3tfoA:
18.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tk3 CYTOCHROME P450 2B4

(Oryctolagus
cuniculus) 		PF00067
(p450) 		5 ILE A 114
ALA A 298
THR A 302
VAL A 367
PRO A 368
 HEM  A 500 (-4.0A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.75A 2nnjA-3tk3A:
53.6		 2nnjA-3tk3A:
55.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT

(Carboxydothermus
hydrogenoformans) 		PF03599
(CdhD)
PF04060
(FeS) 		5 ILE A 159
VAL A 291
ALA A  95
VAL A  66
ILE A  75
 None
 0.99A 2nnjA-4c1nA:
undetectable		 2nnjA-4c1nA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw4 BETA-KETOACYL
SYNTHASE

(Pseudomonas
aeruginosa) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 VAL A 219
ALA A 218
VAL A 212
ILE A 208
VAL A 209
 None
 0.96A 2nnjA-4cw4A:
undetectable		 2nnjA-4cw4A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f55 SPORE CORTEX-LYTIC
ENZYME

(Bacillus cereus) 		PF07486
(Hydrolase_2) 		5 VAL A 169
ALA A 170
VAL A 186
ILE A 190
VAL A 189
 None
 0.86A 2nnjA-4f55A:
undetectable		 2nnjA-4f55A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd0 LEUCINE RICH
HYPOTHETICAL PROTEIN

(Bacteroides
caccae) 		PF07523
(Big_3)
PF13306
(LRR_5) 		5 ILE A 154
ALA A 180
VAL A 186
VAL A 167
ILE A 164
 None
 1.01A 2nnjA-4fd0A:
undetectable		 2nnjA-4fd0A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fet SPORE CORTEX-LYTIC
ENZYME PREPEPTIDE

(Bacillus
anthracis) 		no annotation 5 VAL B 163
ALA B 164
VAL B 180
ILE B 184
VAL B 183
 None
 0.93A 2nnjA-4fetB:
undetectable		 2nnjA-4fetB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4i 6-PHOSPHOFRUCTOKINAS
E

(Geobacillus
stearothermophilus) 		PF00365
(PFK) 		5 ILE A 191
VAL A 224
ALA A 221
ILE A 218
VAL A 165
 None
 0.98A 2nnjA-4i4iA:
undetectable		 2nnjA-4i4iA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9u L-LACTATE
DEHYDROGENASE A
CHAIN

(Oryctolagus
cuniculus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 ILE A  38
LEU A 253
ALA A 259
VAL A 135
ILE A 251
 None
 1.05A 2nnjA-4i9uA:
undetectable		 2nnjA-4i9uA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixu ARGINASE-2,
MITOCHONDRIAL

(Homo sapiens) 		PF00491
(Arginase) 		5 ILE A 252
LEU A 248
VAL A 318
ALA A 315
VAL A 114
 None
 0.94A 2nnjA-4ixuA:
undetectable		 2nnjA-4ixuA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhz BETA-GLUCURONIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		5 ILE A  12
VAL A 128
VAL A  73
ILE A 130
VAL A  99
 None
 1.07A 2nnjA-4jhzA:
undetectable		 2nnjA-4jhzA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kbo STRESS-70 PROTEIN,
MITOCHONDRIAL

(Homo sapiens) 		PF00012
(HSP70) 		5 ILE A 124
ALA A 204
VAL A 219
VAL A 193
ILE A 191
 None
 1.05A 2nnjA-4kboA:
undetectable		 2nnjA-4kboA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lb0 UNCHARACTERIZED
PROTEIN

(Agrobacterium
vitis) 		PF05544
(Pro_racemase) 		5 ILE A 219
ALA A 124
VAL A 128
VAL A 147
PRO A 148
 None
 0.94A 2nnjA-4lb0A:
undetectable		 2nnjA-4lb0A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ln1 L-LACTATE
DEHYDROGENASE 1

(Bacillus cereus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 ILE A 170
LEU A 211
VAL A 189
ALA A 172
VAL A 218
 None
 1.04A 2nnjA-4ln1A:
undetectable		 2nnjA-4ln1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mzd NISIN LEADER
PEPTIDE-PROCESSING
SERINE PROTEASE NISP

(Lactococcus
lactis) 		PF00082
(Peptidase_S8) 		6 ILE A 314
VAL A 323
ALA A 324
VAL A 526
VAL A 359
VAL A 525
 None
 1.44A 2nnjA-4mzdA:
undetectable		 2nnjA-4mzdA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4obt TRIOSEPHOSPHATE
ISOMERASE, CYTOSOLIC

(Arabidopsis
thaliana) 		PF00121
(TIM) 		5 ILE A 151
VAL A 110
VAL A 161
ILE A 125
VAL A  92
 None
 0.96A 2nnjA-4obtA:
undetectable		 2nnjA-4obtA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ole NEXT TO BRCA1 GENE 1
PROTEIN

(Homo sapiens) 		PF16158
(N_BRCA1_IG) 		5 VAL A 472
VAL A 429
VAL A 431
PRO A 432
VAL A 444
 None
 1.06A 2nnjA-4oleA:
undetectable		 2nnjA-4oleA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2h PROLINE RACEMASE
PROTEIN

(Agrobacterium
tumefaciens) 		PF05544
(Pro_racemase) 		5 ILE A 219
ALA A 124
VAL A 128
VAL A 147
PRO A 148
 None
 0.93A 2nnjA-4q2hA:
undetectable		 2nnjA-4q2hA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry9 PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Verminephrobacter
eiseniae) 		PF13407
(Peripla_BP_4) 		5 LEU A  64
ALA A  56
VAL A  40
ILE A  38
VAL A  68
 None
 0.91A 2nnjA-4ry9A:
undetectable		 2nnjA-4ry9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzi 3-KETOACYL-ACYL
CARRIER PROTEIN
REDUCTASE

(Synechocystis
sp. PCC 6803) 		no annotation 5 LEU B   6
ALA B 212
VAL B  80
ILE B  11
VAL B  35
 None
 1.04A 2nnjA-4rziB:
undetectable		 2nnjA-4rziB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wmy INTELECTIN-1

(Homo sapiens) 		no annotation 5 ILE A 149
ALA A 252
VAL A 209
ILE A 207
VAL A 206
 None
 1.06A 2nnjA-4wmyA:
undetectable		 2nnjA-4wmyA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xll DJ-1 FAMILY PROTEIN

(Toxoplasma
gondii) 		PF01965
(DJ-1_PfpI) 		5 LEU A  99
ALA A 161
VAL A  32
VAL A   7
PRO A   8
 None
 0.97A 2nnjA-4xllA:
undetectable		 2nnjA-4xllA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwl BETAINE-ALDEHYDE
DEHYDROGENASE

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		5 ILE A 354
ALA A 347
VAL A 391
VAL A 395
ILE A 340
 None
 1.02A 2nnjA-4zwlA:
undetectable		 2nnjA-4zwlA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3g PROTEIN SHORT-ROOT

(Arabidopsis
thaliana) 		PF03514
(GRAS) 		5 ILE B 385
LEU B 272
VAL B 250
ALA B 249
VAL B 486
 None
 1.02A 2nnjA-5b3gB:
undetectable		 2nnjA-5b3gB:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3h PROTEIN SHORT-ROOT

(Arabidopsis
thaliana) 		PF03514
(GRAS) 		5 ILE B 385
LEU B 272
VAL B 250
ALA B 249
VAL B 486
 None
 1.07A 2nnjA-5b3hB:
undetectable		 2nnjA-5b3hB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Staphylococcus
epidermidis) 		no annotation 5 ILE A 360
LEU A 357
VAL A 342
VAL A 384
VAL A 352
 None
 1.04A 2nnjA-5bndA:
undetectable		 2nnjA-5bndA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuc PLATELET BINDING
PROTEIN GSPB

(Streptococcus
gordonii) 		no annotation 5 ILE A 469
VAL A 405
VAL A 407
PRO A 408
VAL A 425
 None
 1.07A 2nnjA-5iucA:
undetectable		 2nnjA-5iucA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyo CYP101J2

(Sphingobium
yanoikuyae) 		PF00067
(p450) 		5 VAL A 249
THR A 254
VAL A 297
ILE A 397
VAL A 398
 None
HEM  A 501 (-3.5A)
HEM  A 501 (-4.3A)
None
None
 0.72A 2nnjA-5kyoA:
30.2		 2nnjA-5kyoA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o8x SOLUBLE LYTIC
TRANSGLYCOSYLASE B

(Pseudomonas
aeruginosa) 		no annotation 5 ILE A  99
VAL A 201
ALA A 202
ILE A 284
VAL A 283
 None
 1.02A 2nnjA-5o8xA:
undetectable		 2nnjA-5o8xA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olt -

(-) 		no annotation 5 ALA A 496
VAL A 438
VAL A 440
PRO A 441
VAL A 472
 None
 1.02A 2nnjA-5oltA:
undetectable		 2nnjA-5oltA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2w SHORT CHAIN
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00106
(adh_short) 		5 VAL A 218
ALA A 219
VAL A 226
VAL A  89
VAL A 225
 None
 1.07A 2nnjA-5u2wA:
undetectable		 2nnjA-5u2wA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj8 ORIGIN RECOGNITION
COMPLEX SUBUNIT 2

(Homo sapiens) 		PF04084
(ORC2) 		5 ILE E 408
LEU E 390
VAL E 351
THR E 356
ILE E 418
 None
 1.01A 2nnjA-5uj8E:
undetectable		 2nnjA-5uj8E:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vcs ALPHA-1,6-MANNOSYL-G
LYCOPROTEIN
2-BETA-N-ACETYLGLUCO
SAMINYLTRANSFERASE

(Homo sapiens) 		no annotation 5 LEU A 256
VAL A 364
VAL A 366
PRO A 367
VAL A 288
 None
 1.00A 2nnjA-5vcsA:
undetectable		 2nnjA-5vcsA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyw PYRUVATE CARBOXYLASE

(Lactococcus
lactis) 		PF00289
(Biotin_carb_N)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		5 ILE A 212
VAL A 210
THR A 298
VAL A 304
ILE A 331
 None
 0.89A 2nnjA-5vywA:
undetectable		 2nnjA-5vywA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4c THIOREDOXIN
REDUCTASE

(Cryptococcus
neoformans) 		no annotation 5 ALA A 195
THR A 199
VAL A 233
VAL A 235
VAL A 208
 None
 1.04A 2nnjA-5w4cA:
undetectable		 2nnjA-5w4cA:
9.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wbg CYTOCHROME P450 2B6

(Homo sapiens) 		no annotation 5 ILE A 114
ALA A 298
THR A 302
VAL A 367
PRO A 368
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
9ZJ  A 502 ( 4.2A)
None
 0.65A 2nnjA-5wbgA:
52.5		 2nnjA-5wbgA:
61.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xr2 PROTEIN/NUCLEIC ACID
DEGLYCASE HCHA

(Staphylococcus
aureus) 		no annotation 5 LEU A 189
ALA A 194
VAL A 250
PRO A 217
VAL A 213
 None
 0.97A 2nnjA-5xr2A:
undetectable		 2nnjA-5xr2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y09 PROTEASE DO-LIKE 9

(Arabidopsis
thaliana) 		no annotation 6 ILE A 195
LEU A 165
ALA A 168
VAL A 177
VAL A 192
VAL A 131
 None
 1.41A 2nnjA-5y09A:
undetectable		 2nnjA-5y09A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b73 SOLUBLE CYTOCHROME
B562, KAPPA-TYPE
OPIOID RECEPTOR

(Escherichia
coli;
Homo sapiens) 		no annotation 5 LEU A 149
VAL A 282
ALA A 281
ILE A 242
VAL A 239
 None
 1.05A 2nnjA-6b73A:
undetectable		 2nnjA-6b73A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6u -

(-) 		no annotation 5 ALA N  14
VAL N  42
VAL N  44
PRO N  45
VAL N  71
 None
 0.97A 2nnjA-6c6uN:
undetectable		 2nnjA-6c6uN:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dde MU-TYPE OPIOID
RECEPTOR

(Mus musculus) 		no annotation 5 LEU R 158
VAL R 288
ALA R 287
ILE R 248
VAL R 245
 None
 1.06A 2nnjA-6ddeR:
0.9		 2nnjA-6ddeR:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gk6 -

(-) 		no annotation 5 ILE A 125
VAL A 153
ALA A 152
ILE A 252
VAL A 249
 None
 0.87A 2nnjA-6gk6A:
30.7		 2nnjA-6gk6A:
undetectable