SIMILAR PATTERNS OF AMINO ACIDS FOR 2NNH_A_9CRA502
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cja | PROTEIN(ACTIN-FRAGMINKINASE) (Physarumpolycephalum) |
PF09192(Act-Frag_cataly) | 5 | SER A 268ILE A 269ILE A 208ASN A 215VAL A 198 | None | 1.05A | 2nnhA-1cjaA:0.0 | 2nnhA-1cjaA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dhs | DEOXYHYPUSINESYNTHASE (Homo sapiens) |
PF01916(DS) | 5 | SER A 110ILE A 112ILE A 116LEU A 281ASN A 307 | None | 1.01A | 2nnhA-1dhsA:0.2 | 2nnhA-1dhsA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dhs | DEOXYHYPUSINESYNTHASE (Homo sapiens) |
PF01916(DS) | 5 | SER A 110ILE A 112LEU A 281ASN A 307VAL A 286 | None | 0.91A | 2nnhA-1dhsA:0.2 | 2nnhA-1dhsA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gt9 | KUMAMOLYSIN (Bacillussubtilis) |
PF00082(Peptidase_S8) | 5 | ILE 1 291LEU 1 287ASN 1 292VAL 1 313VAL 1 253 | None | 1.02A | 2nnhA-1gt91:0.0 | 2nnhA-1gt91:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nvm | 4-HYDROXY-2-OXOVALERATE ALDOLASEACETALDEHYDEDEHYDROGENASE(ACYLATING) (Pseudomonas sp.CF600) |
PF00682(HMGL-like)PF01118(Semialdhyde_dh)PF07836(DmpG_comm)PF09290(AcetDehyd-dimer) | 5 | SER B 163ILE B 159SER B 160ASN B 290VAL A 322 | NAD B3501 (-4.8A)NoneNoneNAD B3501 (-3.6A)None | 0.93A | 2nnhA-1nvmB:0.0 | 2nnhA-1nvmB:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qyc | PHENYLCOUMARANBENZYLIC ETHERREDUCTASE PT1 (Pinus taeda) |
PF05368(NmrA) | 5 | SER A 163LEU A 227ASN A 225VAL A 187ILE A 179 | None | 1.05A | 2nnhA-1qycA:0.0 | 2nnhA-1qycA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rvv | RIBOFLAVIN SYNTHASE (Bacillussubtilis) |
no annotation | 5 | SER A 32LEU A 78ASN A 134VAL A 50ILE A 26 | None | 1.06A | 2nnhA-1rvvA:0.0 | 2nnhA-1rvvA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sgw | PUTATIVE ABCTRANSPORTER (Pyrococcusfuriosus) |
PF00005(ABC_tran) | 5 | ILE A 58ILE A 47LEU A 3VAL A 148VAL A 30 | None | 1.04A | 2nnhA-1sgwA:0.0 | 2nnhA-1sgwA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xwd | FOLLICLE STIMULATINGHORMONE RECEPTOR (Homo sapiens) |
PF01462(LRRNT)PF13306(LRR_5) | 5 | SER C 201ILE C 225SER C 226LEU C 244ILE C 222 | None | 0.80A | 2nnhA-1xwdC:0.0 | 2nnhA-1xwdC:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yqf | HYPOTHETICAL PROTEINLMAJ011689 (Leishmaniamajor) |
PF02330(MAM33) | 5 | SER A 83ILE A 104ILE A 86LEU A 109VAL A 70 | None | 1.06A | 2nnhA-1yqfA:undetectable | 2nnhA-1yqfA:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a4v | PEROXIREDOXIN DOT5 (Saccharomycescerevisiae) |
PF00578(AhpC-TSA) | 5 | ILE A 82SER A 83ILE A 87LEU A 152VAL A 94 | None | 0.98A | 2nnhA-2a4vA:undetectable | 2nnhA-2a4vA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bvm | TOXIN B (Clostridioidesdifficile) |
PF12918(TcdB_N)PF12919(TcdA_TcdB) | 5 | SER A 393SER A 396ILE A 399ASN A 384LEU A 387 | NoneNoneNoneGLC A1544 (-3.8A)None | 1.01A | 2nnhA-2bvmA:undetectable | 2nnhA-2bvmA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwj | ADENYLATE KINASE 5 (Homo sapiens) |
PF00406(ADK) | 5 | SER A 54SER A 57ILE A 60LEU A 78VAL A 70 | SO4 A1200 (-4.5A)NoneNoneNoneNone | 0.93A | 2nnhA-2bwjA:undetectable | 2nnhA-2bwjA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gqf | HYPOTHETICAL PROTEINHI0933 (Haemophilusinfluenzae) |
PF03486(HI0933_like) | 5 | ILE A 10ILE A 181LEU A 160ASN A 159VAL A 363 | FAD A 403 (-4.9A)NoneNoneNoneNone | 0.89A | 2nnhA-2gqfA:undetectable | 2nnhA-2gqfA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j04 | HYPOTHETICAL PROTEINYPL007C (Saccharomycescerevisiae) |
PF12660(zf-TFIIIC) | 5 | ILE A 39SER A 38ILE A 37VAL A 102ILE A 368 | None | 0.92A | 2nnhA-2j04A:undetectable | 2nnhA-2j04A:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjx | URIDYLATE KINASE (Bacillusanthracis) |
PF00696(AA_kinase) | 5 | ILE A 32ILE A 36LEU A 86VAL A 46VAL A 98 | None | 0.92A | 2nnhA-2jjxA:undetectable | 2nnhA-2jjxA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k9u | GAMMA FILAMIN (Homo sapiens) |
PF00630(Filamin) | 5 | SER A 99ILE A 89SER A 88ILE A 53ASN A 92 | None | 1.02A | 2nnhA-2k9uA:undetectable | 2nnhA-2k9uA:14.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nnj | CYTOCHROME P450 2C8 (Homo sapiens) |
PF00067(p450) | 6 | SER A 100ASN A 209ASN A 217VAL A 237VAL A 296ILE A 476 | NoneNoneNoneNoneNone225 A 501 ( 3.9A) | 0.68A | 2nnhA-2nnjA:62.3 | 2nnhA-2nnjA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nnj | CYTOCHROME P450 2C8 (Homo sapiens) |
PF00067(p450) | 9 | SER A 100ILE A 102ILE A 106ASN A 204LEU A 208ASN A 209ASN A 217VAL A 237VAL A 296 | NonePLM A 502 ( 4.1A)PLM A 502 (-4.6A)None225 A 501 ( 4.3A)NoneNoneNoneNone | 0.59A | 2nnhA-2nnjA:62.3 | 2nnhA-2nnjA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nnj | CYTOCHROME P450 2C8 (Homo sapiens) |
PF00067(p450) | 9 | SER A 100ILE A 102SER A 103ILE A 106ASN A 204ASN A 209ASN A 217VAL A 237VAL A 296 | NonePLM A 502 ( 4.1A)225 A 501 ( 4.0A)PLM A 502 (-4.6A)NoneNoneNoneNoneNone | 0.64A | 2nnhA-2nnjA:62.3 | 2nnhA-2nnjA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nnj | CYTOCHROME P450 2C8 (Homo sapiens) |
PF00067(p450) | 7 | SER A 100ILE A 102SER A 103ILE A 106ASN A 217VAL A 237ARG A 241 | NonePLM A 502 ( 4.1A)225 A 501 ( 4.0A)PLM A 502 (-4.6A)NoneNoneNone | 1.49A | 2nnhA-2nnjA:62.3 | 2nnhA-2nnjA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nz4 | U1 SMALL NUCLEARRIBONUCLEOPROTEIN A (Homo sapiens) |
PF00076(RRM_1) | 5 | ILE A 93SER A 91ILE A 94LEU A 41ILE A 43 | None A P 17 ( 2.8A)NoneNoneNone | 1.04A | 2nnhA-2nz4A:undetectable | 2nnhA-2nz4A:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyj | DNA POLYMERASE (Bacillus virusphi29) |
PF03175(DNA_pol_B_2) | 5 | ILE A 71ILE A 103LEU A 74ASN A 77VAL A 51 | None | 1.01A | 2nnhA-2pyjA:undetectable | 2nnhA-2pyjA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q5o | PHENYLPYRUVATEDECARBOXYLASE (Azospirillumbrasilense) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ILE A 96LEU A 11VAL A 148VAL A 175ILE A 39 | None | 1.02A | 2nnhA-2q5oA:undetectable | 2nnhA-2q5oA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qfv | ISOCITRATEDEHYDROGENASE [NADP] (Saccharomycescerevisiae) |
PF00180(Iso_dh) | 5 | ILE A 32ILE A 27LEU A 361VAL A 401ILE A 409 | None | 0.96A | 2nnhA-2qfvA:undetectable | 2nnhA-2qfvA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v95 | CORTICOSTEROID-BINDING GLOBULIN (Rattusnorvegicus) |
PF00079(Serpin) | 5 | SER A 42SER A 39ILE A 38ASN A 169ILE A 152 | None | 1.03A | 2nnhA-2v95A:undetectable | 2nnhA-2v95A:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xi7 | RNA POLYMERASE L (Californiaencephalitisorthobunyavirus) |
PF15518(L_protein_N) | 5 | ILE A 91ILE A 129LEU A 45ASN A 46VAL A 154 | None | 1.01A | 2nnhA-2xi7A:undetectable | 2nnhA-2xi7A:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3czx | PUTATIVEN-ACETYLMURAMOYL-L-ALANINE AMIDASE (Neisseriameningitidis) |
PF01520(Amidase_3) | 5 | ILE A 168ILE A 172ASN A 34VAL A 72VAL A 48 | None | 1.05A | 2nnhA-3czxA:undetectable | 2nnhA-3czxA:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fe3 | MAP/MICROTUBULEAFFINITY-REGULATINGKINASE 3 (Homo sapiens) |
PF00069(Pkinase)PF00627(UBA) | 5 | ILE A 307LEU A 283ASN A 282ASN A 308VAL A 236 | None | 1.05A | 2nnhA-3fe3A:undetectable | 2nnhA-3fe3A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fk5 | 3-OXOACYL-SYNTHASEIII (Xanthomonasoryzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | ILE A 142LEU A 137ASN A 5VAL A 191VAL A 198 | None | 0.96A | 2nnhA-3fk5A:undetectable | 2nnhA-3fk5A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fsc | QDTC (Thermoanaerobacteriumthermosaccharolyticum) |
PF00132(Hexapep) | 5 | ILE A 144SER A 143ILE A 145ASN A 192VAL A 131 | None | 1.00A | 2nnhA-3fscA:undetectable | 2nnhA-3fscA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5o | UNCHARACTERIZEDPROTEIN RV2865UNCHARACTERIZEDPROTEIN RV2866 (Mycobacteriumtuberculosis) |
PF02604(PhdYeFM_antitox)PF05016(ParE_toxin) | 5 | ILE A 71SER A 70ILE A 67LEU B 78ILE B 90 | None | 1.04A | 2nnhA-3g5oA:undetectable | 2nnhA-3g5oA:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hcs | TNFRECEPTOR-ASSOCIATEDFACTOR 6 (Homo sapiens) |
PF13923(zf-C3HC4_2) | 5 | ILE A 98SER A 97ILE A 94LEU A 112VAL A 81 | None | 0.96A | 2nnhA-3hcsA:undetectable | 2nnhA-3hcsA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hct | TNFRECEPTOR-ASSOCIATEDFACTOR 6 (Homo sapiens) |
PF13923(zf-C3HC4_2) | 5 | ILE A 98SER A 97ILE A 94LEU A 112VAL A 81 | None | 0.98A | 2nnhA-3hctA:undetectable | 2nnhA-3hctA:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hid | ADENYLOSUCCINATESYNTHETASE (Yersinia pestis) |
PF00709(Adenylsucc_synt) | 6 | ILE A 56ILE A 69LEU A 80VAL A 73VAL A 149ILE A 197 | None | 1.23A | 2nnhA-3hidA:undetectable | 2nnhA-3hidA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4p | TRANSCRIPTIONALREGULATOR, ASNCFAMILY (Agrobacteriumfabrum) |
PF01037(AsnC_trans_reg)PF13412(HTH_24) | 5 | ILE A 47ILE A 38LEU A 12VAL A 20VAL A 27 | None | 0.99A | 2nnhA-3i4pA:undetectable | 2nnhA-3i4pA:16.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4s | FTSZ/TUBULIN-RELATEDPROTEIN (Bacillusthuringiensis) |
PF00091(Tubulin) | 5 | ILE A 209LEU A 248ASN A 252ASN A 207ILE A 23 | None | 0.94A | 2nnhA-3j4sA:undetectable | 2nnhA-3j4sA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j7y | BL21ML43 (Homo sapiens) |
PF00829(Ribosomal_L21p)no annotation | 5 | ILE S 195SER S 197ILE S 198ASN b 123VAL S 136 | None | 0.99A | 2nnhA-3j7yS:undetectable | 2nnhA-3j7yS:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k6i | T-CADHERIN (Gallus gallus) |
PF00028(Cadherin) | 5 | ILE A 25ILE A 2ASN A 53VAL A 91ILE A 55 | None | 1.04A | 2nnhA-3k6iA:undetectable | 2nnhA-3k6iA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kw3 | ALANINE RACEMASE (Bartonellahenselae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 6 | ILE A 285SER A 284ILE A 283LEU A 338VAL A 321ILE A 18 | None | 1.46A | 2nnhA-3kw3A:undetectable | 2nnhA-3kw3A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm5 | SERINE/THREONINE-PROTEIN KINASE 17B (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 81ILE A 77LEU A 108ARG A 68ILE A 94 | NoneNoneNoneNoneQUE A 1 (-4.6A) | 0.98A | 2nnhA-3lm5A:undetectable | 2nnhA-3lm5A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pmo | UDP-3-O-[3-HYDROXYMYRISTOYL] GLUCOSAMINEN-ACYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00132(Hexapep)PF04613(LpxD) | 5 | ILE A 238ILE A 240VAL A 244VAL A 204ILE A 175 | None | 1.00A | 2nnhA-3pmoA:undetectable | 2nnhA-3pmoA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pry | HEAT SHOCK PROTEINHSP 90-BETA (Homo sapiens) |
PF00183(HSP90) | 5 | ILE A 400ILE A 404LEU A 386ASN A 389VAL A 381 | None | 0.94A | 2nnhA-3pryA:undetectable | 2nnhA-3pryA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3q | SUPPRESSOR PROTEINSTP22 OFTEMPERATURE-SENSITIVE ALPHA-FACTORRECEPTOR ANDARGININE PERMEASE (Saccharomycescerevisiae) |
PF05743(UEV) | 5 | ILE A 81SER A 80ILE A 69LEU A 152VAL A 145 | None | 1.01A | 2nnhA-3r3qA:undetectable | 2nnhA-3r3qA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7t | ADENYLOSUCCINATESYNTHETASE (Campylobacterjejuni) |
PF00709(Adenylsucc_synt) | 5 | ILE A 69LEU A 80VAL A 73VAL A 145ILE A 192 | None | 1.02A | 2nnhA-3r7tA:undetectable | 2nnhA-3r7tA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3syj | ADHESION ANDPENETRATION PROTEINAUTOTRANSPORTER (Haemophilusinfluenzae) |
PF02395(Peptidase_S6)PF03212(Pertactin) | 5 | SER A 379ILE A 381SER A 308LEU A 331ASN A 333 | None | 1.05A | 2nnhA-3syjA:undetectable | 2nnhA-3syjA:18.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tov | GLYCOSYL TRANSFERASEFAMILY 9 (Veillonellaparvula) |
PF01075(Glyco_transf_9) | 5 | ILE A 8ILE A 91LEU A 29ASN A 55VAL A 143 | None | 1.01A | 2nnhA-3tovA:undetectable | 2nnhA-3tovA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4p | INTEGRIN ALPHA-4 (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 5 | ILE A 369ILE A 367LEU A 342ASN A 341VAL A 417 | None | 0.92A | 2nnhA-3v4pA:undetectable | 2nnhA-3v4pA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wo8 | BETA-N-ACETYLGLUCOSAMINIDASE (Thermotogamaritima) |
PF00933(Glyco_hydro_3) | 6 | ILE A 60SER A 61ILE A 34ASN A 109VAL A 38VAL A 71 | None | 1.39A | 2nnhA-3wo8A:undetectable | 2nnhA-3wo8A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a01 | PROTONPYROPHOSPHATASE (Vigna radiata) |
PF03030(H_PPase) | 5 | ILE A 81SER A 82ASN A 168VAL A 631ILE A 288 | None | 1.01A | 2nnhA-4a01A:1.9 | 2nnhA-4a01A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aco | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITA (Saccharomycescerevisiae) |
PF16787(NDC10_II) | 5 | ILE A 53LEU A 132ASN A 130ASN A 141ILE A 146 | None | 1.02A | 2nnhA-4acoA:undetectable | 2nnhA-4acoA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwf | UBIQUITIN-CONJUGATING ENZYME E2-21 KDA (Saccharomycescerevisiae) |
PF00179(UQ_con) | 5 | ILE A 80SER A 96ILE A 95VAL A 84ILE A 53 | None | 1.02A | 2nnhA-4bwfA:undetectable | 2nnhA-4bwfA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp6 | CHOLINE BINDINGPROTEIN PCPA (Streptococcuspneumoniae) |
PF13306(LRR_5) | 6 | ILE A 394ILE A 392ASN A 435LEU A 427ASN A 430VAL A 414 | None | 1.45A | 2nnhA-4cp6A:undetectable | 2nnhA-4cp6A:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d3g | PSTA (Staphylococcusaureus) |
PF06153(CdAMP_rec) | 5 | ILE A 60SER A 58ILE A 56LEU A 20VAL A 48 | None | 1.05A | 2nnhA-4d3gA:undetectable | 2nnhA-4d3gA:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dib | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bacillusanthracis) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | ILE A 292ILE A 293ASN A 154ASN A 287VAL A 308 | None | 0.93A | 2nnhA-4dibA:undetectable | 2nnhA-4dibA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emk | U6 SNRNA-ASSOCIATEDSM-LIKE PROTEIN LSM5U6 SNRNA-ASSOCIATEDSM-LIKE PROTEIN LSM7 (Schizosaccharomycespombe) |
PF01423(LSM) | 5 | ILE A 42ILE A 11LEU A 19ASN A 18VAL C 87 | None | 1.01A | 2nnhA-4emkA:undetectable | 2nnhA-4emkA:11.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ffl | PYLC (Methanosarcinabarkeri) |
PF02655(ATP-grasp_3) | 5 | ILE A 100SER A 101ILE A 240LEU A 218VAL A 172 | None | 1.03A | 2nnhA-4fflA:undetectable | 2nnhA-4fflA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fn4 | SHORT CHAINDEHYDROGENASE (Sulfolobusacidocaldarius) |
PF13561(adh_short_C2) | 5 | ILE A 20ILE A 230VAL A 141VAL A 11ILE A 48 | NAD A 501 (-4.0A)NoneNoneNoneNone | 0.91A | 2nnhA-4fn4A:undetectable | 2nnhA-4fn4A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fo1 | LINCOSAMIDERESISTANCE PROTEIN (Staphylococcushaemolyticus) |
PF10706(Aminoglyc_resit) | 5 | ILE A 49ILE A 47LEU A 27VAL A 6ILE A 132 | None | 1.06A | 2nnhA-4fo1A:undetectable | 2nnhA-4fo1A:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gc5 | DIMETHYLADENOSINETRANSFERASE 1,MITOCHONDRIAL (Mus musculus) |
PF00398(RrnaAD) | 5 | ILE A 152ILE A 151LEU A 196VAL A 206ILE A 198 | None | 0.97A | 2nnhA-4gc5A:undetectable | 2nnhA-4gc5A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h44 | APOCYTOCHROME F (Nostoc sp. PCC7120) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 5 | ILE C 52ILE C 127VAL C 101VAL C 114ILE C 20 | None | 0.94A | 2nnhA-4h44C:undetectable | 2nnhA-4h44C:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ks9 | MALONYL-COADECARBOXYLASE (Cupriavidusmetallidurans) |
PF05292(MCD)PF17408(MCD_N) | 5 | ILE A 252SER A 291ILE A 290VAL A 256ILE A 201 | None | 1.00A | 2nnhA-4ks9A:undetectable | 2nnhA-4ks9A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ksa | MALONYL-COADECARBOXYLASE (Rhodopseudomonaspalustris) |
PF05292(MCD)PF17408(MCD_N) | 5 | ILE A 236SER A 275ILE A 274VAL A 240ILE A 184 | None | 1.01A | 2nnhA-4ksaA:undetectable | 2nnhA-4ksaA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l82 | RIFEA.00250.A (Rickettsiafelis) |
PF01613(Flavin_Reduct) | 5 | ILE A 74SER A 73ILE A 117LEU A 40VAL A 137 | None | 0.83A | 2nnhA-4l82A:undetectable | 2nnhA-4l82A:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mki | ENERGY-COUPLINGFACTOR TRANSPORTERATP-BINDING PROTEINECFA2 (Caldanaerobactersubterraneus) |
no annotation | 5 | ILE B 30LEU B 53ASN B 54VAL B 36ILE B 81 | None | 1.04A | 2nnhA-4mkiB:undetectable | 2nnhA-4mkiB:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4myc | IRON-SULFUR CLUSTERSTRANSPORTER ATM1,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 6 | SER A 574ILE A 573ASN A 529LEU A 581VAL A 566ILE A 583 | None | 1.49A | 2nnhA-4mycA:0.0 | 2nnhA-4mycA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ogq | APOCYTOCHROME F (Nostoc sp. PCC7120) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 5 | ILE C 52ILE C 127VAL C 101VAL C 114ILE C 20 | None | 0.94A | 2nnhA-4ogqC:undetectable | 2nnhA-4ogqC:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4on9 | PROBABLEATP-DEPENDENT RNAHELICASE DDX58 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | ILE A 713ILE A 617LEU A 711ASN A 710ILE A 629 | None | 1.06A | 2nnhA-4on9A:undetectable | 2nnhA-4on9A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oou | BETA-1,4-MANNANASE (Cryptopygusantarcticus) |
no annotation | 5 | ILE B 225SER B 226ILE B 229LEU B 131VAL B 164 | None | 0.96A | 2nnhA-4oouB:undetectable | 2nnhA-4oouB:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tz0 | ATP-DEPENDENT RNAHELICASE MSS116,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | ILE A 451SER A 355VAL A 515VAL A 561ILE A 555 | None | 1.01A | 2nnhA-4tz0A:undetectable | 2nnhA-4tz0A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yai | CALPHA-DEHYDROGENASE (Sphingobium sp.SYK-6) |
PF00106(adh_short) | 5 | ILE A 120LEU A 116ASN A 115ASN A 121ILE A 114 | NoneNoneNAI A 500 ( 4.4A)NoneNAI A 500 (-3.4A) | 1.03A | 2nnhA-4yaiA:undetectable | 2nnhA-4yaiA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bvq | FATTY ACID-BINDINGPROTEIN (Pygoscelispapua) |
PF00061(Lipocalin) | 5 | ILE A 50ILE A 43LEU A 92ASN A 93VAL A 116 | None | 0.88A | 2nnhA-5bvqA:undetectable | 2nnhA-5bvqA:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bxp | LACTO-N-BIOSIDASE (Bifidobacteriumbifidum) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b)PF14200(RicinB_lectin_2) | 5 | ILE A 198SER A 194ILE A 193VAL A 477ILE A 518 | None | 1.05A | 2nnhA-5bxpA:undetectable | 2nnhA-5bxpA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5byp | PUTATIVEUNCHARACTERIZEDPROTEIN (Bacteroideseggerthii) |
PF16585(Lipocalin_8) | 5 | ILE A 87SER A 88ILE A 89LEU A 138ASN A 139 | None | 1.01A | 2nnhA-5bypA:undetectable | 2nnhA-5bypA:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czz | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Staphylococcusaureus) |
PF13395(HNH_4)PF16592(Cas9_REC) | 5 | SER A 457ILE A 461LEU A 7VAL A 673ILE A 708 | None | 1.03A | 2nnhA-5czzA:1.5 | 2nnhA-5czzA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5r | HEAT SHOCK PROTEIN75 KDA,MITOCHONDRIAL (Homo sapiens) |
PF13589(HATPase_c_3) | 5 | ILE A 253ILE A 255LEU A 116VAL A 211ILE A 143 | None | 0.96A | 2nnhA-5f5rA:undetectable | 2nnhA-5f5rA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5frd | CARBOXYLESTERASE(EST-2) (Archaeoglobusfulgidus) |
PF12697(Abhydrolase_6) | 6 | SER A 75ILE A 49ILE A 27LEU A 51ASN A 53VAL A 65 | None | 1.48A | 2nnhA-5frdA:undetectable | 2nnhA-5frdA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gkq | ALYGC MUTANT - R241A (Paraglaciecolachathamensis) |
PF14592(Chondroitinas_B) | 5 | ILE A 216ILE A 217ASN A 229VAL A 202VAL A 248 | None | 0.99A | 2nnhA-5gkqA:undetectable | 2nnhA-5gkqA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | ILE A 331SER A 330ILE A 307LEU A 335ASN A 337 | None | 1.06A | 2nnhA-5gr8A:undetectable | 2nnhA-5gr8A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hci | GPN-LOOP GTPASE 1 (Saccharomycescerevisiae) |
PF03029(ATP_bind_1) | 5 | ILE A 104ILE A 6LEU A 23VAL A 252VAL A 171 | None | 0.95A | 2nnhA-5hciA:undetectable | 2nnhA-5hciA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hph | HEAT SHOCK PROTEIN75 KDA,MITOCHONDRIAL (Homo sapiens) |
PF00183(HSP90)PF13589(HATPase_c_3) | 5 | ILE A 253ILE A 255LEU A 116VAL A 211ILE A 143 | None | 0.98A | 2nnhA-5hphA:undetectable | 2nnhA-5hphA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hph | HEAT SHOCK PROTEIN75 KDA,MITOCHONDRIAL (Homo sapiens) |
PF00183(HSP90)PF13589(HATPase_c_3) | 5 | ILE A 411ILE A 379LEU A 405ASN A 399VAL A 391 | None | 1.02A | 2nnhA-5hphA:undetectable | 2nnhA-5hphA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iig | VACUOLAR TRANSPORTERCHAPERONE 4 (Saccharomycescerevisiae) |
PF03105(SPX)PF09359(VTC) | 5 | SER A 375ILE A 374VAL A 441VAL A 450ILE A 208 | None | 0.96A | 2nnhA-5iigA:2.1 | 2nnhA-5iigA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldy | IG DOMAIN PROTEINGROUP 1 DOMAINPROTEIN (Yersiniapseudotuberculosis) |
PF09134(Invasin_D3) | 5 | SER A1924ILE A1871LEU A1894ASN A1893VAL A1947 | None | 0.88A | 2nnhA-5ldyA:undetectable | 2nnhA-5ldyA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lnk | MITOCHONDRIALCOMPLEX I, 39 KDASUBUNIT (Ovis aries) |
no annotation | 5 | ILE d 214ILE d 92LEU d 34ASN d 36VAL d 45 | None | 0.99A | 2nnhA-5lnkd:undetectable | 2nnhA-5lnkd:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lq6 | VIRULENCE PROTEINVSDE (Salmonellaenterica) |
PF05563(SpvD) | 5 | ILE A 189SER A 183LEU A 190VAL A 167ILE A 196 | None | 1.04A | 2nnhA-5lq6A:undetectable | 2nnhA-5lq6A:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lt1 | KINESIN-LIKE PROTEIN (Homo sapiens) |
PF00225(Kinesin) | 5 | ILE A 111ILE A 115VAL A 212VAL A 173ILE A 183 | None | 1.02A | 2nnhA-5lt1A:undetectable | 2nnhA-5lt1A:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqp | GLYCOSIDE HYDROLASEBT_1002 (Bacteroidesthetaiotaomicron) |
no annotation | 5 | ILE A 483ILE A 491ASN A 541VAL A 509ILE A 546 | None | 0.90A | 2nnhA-5mqpA:undetectable | 2nnhA-5mqpA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ncs | SERPIN (Tannerellaforsythia) |
PF00079(Serpin) | 5 | SER A 70SER A 67ILE A 66ASN A 197ILE A 180 | None | 1.06A | 2nnhA-5ncsA:undetectable | 2nnhA-5ncsA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o3m | PROTOCATECHUATEDECARBOXYLASE (Klebsiellapneumoniae) |
PF01977(UbiD) | 5 | ILE A 263ILE A 265LEU A 135VAL A 306VAL A 174 | None | 1.03A | 2nnhA-5o3mA:undetectable | 2nnhA-5o3mA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o60 | 50S RIBOSOMALPROTEIN L25 (Mycolicibacteriumsmegmatis) |
PF01386(Ribosomal_L25p)PF14693(Ribosomal_TL5_C) | 5 | SER W 163ILE W 162LEU W 170VAL W 178VAL W 110 | None | 1.02A | 2nnhA-5o60W:undetectable | 2nnhA-5o60W:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sy7 | NEURONAL PASDOMAIN-CONTAININGPROTEIN 3 (Mus musculus) |
PF00010(HLH)PF00989(PAS)PF08447(PAS_3) | 5 | SER B 415ILE B 383LEU B 346ASN B 347ILE B 348 | None | 1.04A | 2nnhA-5sy7B:undetectable | 2nnhA-5sy7B:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szq | PROTOCADHERINGAMMA-A4 (Mus musculus) |
PF00028(Cadherin) | 5 | ILE A 392ILE A 410LEU A 376VAL A 321ILE A 378 | None | 1.00A | 2nnhA-5szqA:undetectable | 2nnhA-5szqA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8e | ARGININE KINASE (Polybetespythagoricus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | ILE A 350ILE A 346LEU A 287VAL A 283VAL A 308 | None | 1.06A | 2nnhA-5u8eA:undetectable | 2nnhA-5u8eA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vfa | RESPONSE REGULATOR (Streptococcuspneumoniae) |
no annotation | 6 | ILE A 114SER A 115ILE A 117LEU A 49VAL A 98ARG A 161 | None | 1.49A | 2nnhA-5vfaA:undetectable | 2nnhA-5vfaA:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vnz | TNFRECEPTOR-ASSOCIATEDFACTOR 6 (Danio rerio) |
no annotation | 5 | ILE A 99SER A 98ILE A 95LEU A 113VAL A 82 | None | 1.00A | 2nnhA-5vnzA:undetectable | 2nnhA-5vnzA:12.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cy1 | SIGNAL RECOGNITIONPARTICLE RECEPTORFTSY (Elizabethkingiaanophelis) |
no annotation | 5 | ILE A 70ILE A 66LEU A 89VAL A 58VAL A 310 | None | 1.02A | 2nnhA-6cy1A:undetectable | 2nnhA-6cy1A:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cza | - (-) |
no annotation | 5 | ILE A 354ILE A 357LEU A 279VAL A 252VAL A 370 | None | 0.95A | 2nnhA-6czaA:undetectable | 2nnhA-6czaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d14 | TNFRECEPTOR-ASSOCIATEDPROTEIN 1 (Danio rerio) |
no annotation | 5 | ILE A 426ILE A 394LEU A 420ASN A 414VAL A 406 | None | 1.05A | 2nnhA-6d14A:undetectable | 2nnhA-6d14A:10.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gsa | - (-) |
no annotation | 5 | ILE E 53LEU E 132ASN E 130ASN E 141ILE E 146 | None | 1.02A | 2nnhA-6gsaE:undetectable | 2nnhA-6gsaE:undetectable |