SIMILAR PATTERNS OF AMINO ACIDS FOR 2M9Q_B_BEZB251_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aye PROCARBOXYPEPTIDASE
A2

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		5 LEU A 107
ILE A 105
ILE A  86
ALA A  79
LEU A  64
 None
 1.19A 2m9qA-1ayeA:
0.0		 2m9qA-1ayeA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bqg D-GLUCARATE
DEHYDRATASE

(Pseudomonas
putida) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 LEU A 388
ILE A 390
THR A 373
THR A 358
ALA A 355
 None
 1.19A 2m9qA-1bqgA:
0.0		 2m9qA-1bqgA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)

(Homo sapiens) 		PF00168
(C2)
PF01735
(PLA2_B) 		5 ILE A 192
ILE A 572
PHE A 205
THR A 701
ALA A 211
 None
 1.17A 2m9qA-1cjyA:
1.0		 2m9qA-1cjyA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dtd CARBOXYPEPTIDASE A2

(Homo sapiens) 		PF00246
(Peptidase_M14) 		5 LEU A 462
ILE A 460
ILE A 441
ALA A 434
LEU A 419
 None
 1.15A 2m9qA-1dtdA:
0.0		 2m9qA-1dtdA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dz3 STAGE 0 SPORULATION
PROTEIN A

(Geobacillus
stearothermophilus) 		PF00072
(Response_reg) 		5 ILE A  81
ILE A  51
VAL A   5
ALA A   8
LEU A  83
 None
 1.08A 2m9qA-1dz3A:
undetectable		 2m9qA-1dz3A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8f BENZYL ALCOHOL
DEHYDROGENASE

(Acinetobacter
calcoaceticus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		5 ILE A 240
ILE A 219
VAL A 195
THR A 196
ALA A 199
 None
 1.14A 2m9qA-1f8fA:
undetectable		 2m9qA-1f8fA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htr GASTRICSIN

(Homo sapiens) 		PF00026
(Asp) 		5 LEU B 271
ILE B 277
THR B 237
VAL B 286
LEU B 260
 None
 1.20A 2m9qA-1htrB:
0.0		 2m9qA-1htrB:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i17 PRION-LIKE PROTEIN

(Mus musculus) 		PF00377
(Prion) 		5 LEU A  88
ILE A  89
ILE A  40
PHE A  71
LEU A  85
 None
 1.15A 2m9qA-1i17A:
undetectable		 2m9qA-1i17A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lk5 D-RIBOSE-5-PHOSPHATE
ISOMERASE

(Pyrococcus
horikoshii) 		PF06026
(Rib_5-P_isom_A) 		5 ILE A  24
ILE A  51
PHE A  35
ALA A  64
LEU A  26
 None
 1.15A 2m9qA-1lk5A:
0.0		 2m9qA-1lk5A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lr0 TOLA PROTEIN

(Pseudomonas
aeruginosa) 		PF13103
(TonB_2) 		5 ILE A  58
ILE A  66
PHE A 116
VAL A  91
ALA A  86
 None
 1.13A 2m9qA-1lr0A:
undetectable		 2m9qA-1lr0A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tcs TRICHOSANTHIN

(Trichosanthes
kirilowii) 		PF00161
(RIP) 		5 ILE A  71
PHE A  17
VAL A  62
ALA A  48
LEU A  21
 NDP  A 280 (-4.5A)
None
None
None
None
 1.15A 2m9qA-1tcsA:
undetectable		 2m9qA-1tcsA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcz RNASE NGR3

(Nicotiana
glutinosa) 		PF00445
(Ribonuclease_T2) 		5 ILE A 169
ILE A 157
PHE A  36
ALA A 146
LEU A 125
 None
 1.00A 2m9qA-1vczA:
undetectable		 2m9qA-1vczA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcz GLUTAMYL
ENDOPEPTIDASE

(Staphylococcus
aureus) 		PF13365
(Trypsin_2) 		5 ILE A  25
PHE A  99
VAL A  53
THR A  56
ALA A  62
 None
 1.13A 2m9qA-1wczA:
6.4		 2m9qA-1wczA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf3 GTP-BINDING PROTEIN

(Thermus
thermophilus) 		PF01926
(MMR_HSR1)
PF07650
(KH_2) 		5 ILE A 256
ILE A 253
VAL A 278
ALA A 232
LEU A 197
 None
 1.03A 2m9qA-1wf3A:
undetectable		 2m9qA-1wf3A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9j PROBABLE BUTYRATE
KINASE 2

(Thermotoga
maritima) 		PF00871
(Acetate_kinase) 		5 LEU A 156
THR A 302
VAL A 161
THR A 160
ALA A 337
 None
 1.12A 2m9qA-1x9jA:
undetectable		 2m9qA-1x9jA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zd0 HYPOTHETICAL PROTEIN
PF0523

(Pyrococcus
furiosus) 		PF08617
(CGI-121) 		5 ILE A  20
THR A  56
VAL A 104
THR A 105
ALA A 110
 None
 1.17A 2m9qA-1zd0A:
undetectable		 2m9qA-1zd0A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zef ALKALINE PHOSPHATASE

(Homo sapiens) 		PF00245
(Alk_phosphatase) 		5 LEU A 351
ILE A  38
ILE A 458
PHE A 307
ALA A 465
 None
 1.07A 2m9qA-1zefA:
undetectable		 2m9qA-1zefA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvd SMAD UBIQUITINATION
REGULATORY FACTOR 2

(Homo sapiens) 		PF00632
(HECT) 		5 ILE A 720
ILE A 722
PHE A 698
ALA A 659
LEU A 671
 None
 1.05A 2m9qA-1zvdA:
undetectable		 2m9qA-1zvdA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2byo LIPOPROTEIN LPPX

(Mycobacterium
tuberculosis) 		PF07161
(LppX_LprAFG) 		5 LEU A  24
ILE A  28
ILE A 173
ALA A 133
LEU A 131
 None
HXA  A1215 ( 4.8A)
None
None
None
 1.16A 2m9qA-2byoA:
undetectable		 2m9qA-2byoA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cxe RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Pyrococcus
horikoshii) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 ILE A 227
THR A 268
VAL A 249
ALA A 277
LEU A 261
 None
 1.06A 2m9qA-2cxeA:
undetectable		 2m9qA-2cxeA:
21.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fom POLYPROTEIN

(Dengue virus) 		PF00949
(Peptidase_S7) 		5 ILE B  36
PHE B  46
VAL B  52
ALA B  56
LEU B  58
 None
None
None
GOL  B 203 ( 4.0A)
None
 1.10A 2m9qA-2fomB:
11.4		 2m9qA-2fomB:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fom POLYPROTEIN
POLYPROTEIN

(Dengue virus;
Dengue virus) 		PF01002
(Flavi_NS2B)
PF00949
(Peptidase_S7) 		6 LEU A  51
PHE B  46
THR B  48
VAL B  52
ALA B  56
LEU B  58
 None
None
None
None
GOL  B 203 ( 4.0A)
None
 0.90A 2m9qA-2fomA:
undetectable		 2m9qA-2fomA:
90.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus) 		PF00343
(Phosphorylase) 		5 ILE A 308
ILE A 307
PHE A 326
THR A 371
LEU A 353
 None
 1.19A 2m9qA-2gj4A:
undetectable		 2m9qA-2gj4A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 ILE A 248
VAL A  15
THR A  16
ALA A  97
LEU A  93
 None
 1.14A 2m9qA-2gp6A:
undetectable		 2m9qA-2gp6A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gt1 LIPOPOLYSACCHARIDE
HEPTOSYLTRANSFERASE-
1

(Escherichia
coli) 		PF01075
(Glyco_transf_9) 		5 ILE A   5
ILE A  91
THR A 144
ALA A  24
LEU A  21
 None
 1.18A 2m9qA-2gt1A:
undetectable		 2m9qA-2gt1A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv9 DNA POLYMERASE

(Human
alphaherpesvirus
1) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		5 LEU A1188
ILE A1192
PHE A1162
ALA A1169
LEU A1166
 None
 1.12A 2m9qA-2gv9A:
undetectable		 2m9qA-2gv9A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzl 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Escherichia
coli) 		PF02542
(YgbB) 		5 ILE A  18
ILE A  20
PHE A  12
VAL A  39
ALA A  33
 None
 1.13A 2m9qA-2gzlA:
undetectable		 2m9qA-2gzlA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv0 ISOCITRATE
DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF00180
(Iso_dh) 		5 LEU A 110
ILE A 114
PHE A  33
THR A  84
LEU A  99
 None
 1.12A 2m9qA-2iv0A:
undetectable		 2m9qA-2iv0A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3r ZGC 92866

(Danio rerio) 		PF04051
(TRAPP) 		5 LEU B  69
ILE B 150
ILE B  89
ALA B  96
LEU B  65
 None
 1.11A 2m9qA-2j3rB:
undetectable		 2m9qA-2j3rB:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7q MCMV TEGUMENT
PROTEIN M48 ENCODED
UBIQUITIN- SPECIFIC
PROTEASE, M48USP

(Murid
betaherpesvirus
1) 		PF04843
(Herpes_teg_N) 		5 ILE A 134
PHE A 121
VAL A 147
THR A 152
ALA A 177
 None
 1.12A 2m9qA-2j7qA:
undetectable		 2m9qA-2j7qA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jqz E3 UBIQUITIN-PROTEIN
LIGASE SMURF2

(Homo sapiens) 		PF00168
(C2) 		5 LEU A 117
ILE A  77
THR A  50
VAL A  18
ALA A  21
 None
 1.18A 2m9qA-2jqzA:
undetectable		 2m9qA-2jqzA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqo PROTEIN HNRNPL

(Rattus
norvegicus) 		PF00076
(RRM_1) 		5 LEU A 113
ILE A 157
PHE A 139
VAL A 166
ALA A 135
 None
 0.89A 2m9qA-2mqoA:
undetectable		 2m9qA-2mqoA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nnj CYTOCHROME P450 2C8

(Homo sapiens) 		PF00067
(p450) 		5 LEU A 128
PHE A 263
THR A 290
ALA A 436
LEU A 131
 None
None
None
HEM  A 500 (-3.7A)
HEM  A 500 ( 4.9A)
 1.17A 2m9qA-2nnjA:
undetectable		 2m9qA-2nnjA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		5 LEU A 420
ILE A 363
VAL A 366
ALA A 374
LEU A 417
 None
 1.17A 2m9qA-2xh1A:
undetectable		 2m9qA-2xh1A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z65 LYMPHOCYTE ANTIGEN
96

(Homo sapiens) 		PF02221
(E1_DerP2_DerF2) 		5 ILE C  46
ILE C  63
PHE C 151
ALA C 137
LEU C 149
 E55  C   1 (-4.6A)
E55  C   1 ( 4.5A)
E55  C   1 (-3.9A)
None
None
 1.15A 2m9qA-2z65C:
undetectable		 2m9qA-2z65C:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf0 PROTEASE 4

(Escherichia
coli) 		PF01343
(Peptidase_S49) 		5 ILE A 414
ILE A 337
THR A 352
VAL A 347
LEU A 370
 None
 1.18A 2m9qA-3bf0A:
undetectable		 2m9qA-3bf0A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		5 LEU A 462
ILE A 459
ILE A 523
ALA A 359
LEU A 355
 None
 1.13A 2m9qA-3cskA:
undetectable		 2m9qA-3cskA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d54 PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE 1

(Thermotoga
maritima) 		PF13507
(GATase_5) 		5 ILE D 136
THR D 127
VAL D 119
ALA D 171
LEU D 183
 None
 1.08A 2m9qA-3d54D:
undetectable		 2m9qA-3d54D:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ics COENZYME A-DISULFIDE
REDUCTASE

(Bacillus
anthracis) 		PF00581
(Rhodanese)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 LEU A 112
ILE A 282
ILE A 286
VAL A 268
THR A 274
 None
 1.11A 2m9qA-3icsA:
undetectable		 2m9qA-3icsA:
18.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3lkw FUSION PROTEIN OF
NONSTRUCTURAL
PROTEIN 2B AND
NONSTRUCTURAL
PROTEIN 3

(Dengue virus) 		PF00949
(Peptidase_S7)
PF01002
(Flavi_NS2B) 		5 PHE A  96
THR A  98
VAL A 102
ALA A 106
LEU A 108
 None
 0.74A 2m9qA-3lkwA:
6.5		 2m9qA-3lkwA:
63.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m9v FAD-DEPENDENT
OXIDOREDUCTASE

(Actinomadura
kijaniata) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		5 LEU A  62
PHE A  54
THR A  96
VAL A  89
LEU A  57
 None
 1.17A 2m9qA-3m9vA:
undetectable		 2m9qA-3m9vA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nas BETA-PHOSPHOGLUCOMUT
ASE

(Bacillus
subtilis) 		PF13419
(HAD_2) 		5 LEU A 126
ILE A  96
PHE A 132
THR A  13
LEU A 123
 None
 1.12A 2m9qA-3nasA:
undetectable		 2m9qA-3nasA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nep MALATE DEHYDROGENASE

(Salinibacter
ruber) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 ILE X 227
ILE X 224
VAL X 212
THR X 206
ALA X 189
 None
 1.15A 2m9qA-3nepX:
undetectable		 2m9qA-3nepX:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oc4 OXIDOREDUCTASE,
PYRIDINE
NUCLEOTIDE-DISULFIDE
FAMILY

(Enterococcus
faecalis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 LEU A 107
ILE A 275
ILE A 279
VAL A 261
THR A 267
 None
 1.16A 2m9qA-3oc4A:
undetectable		 2m9qA-3oc4A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r27 HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN L

(Homo sapiens) 		PF00076
(RRM_1) 		5 LEU A 118
ILE A 162
PHE A 144
VAL A 171
ALA A 140
 None
GOL  A 181 (-4.6A)
None
None
None
 0.89A 2m9qA-3r27A:
undetectable		 2m9qA-3r27A:
15.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3u1j SERINE PROTEASE NS3

(Dengue virus) 		PF00949
(Peptidase_S7) 		5 PHE B  46
THR B  48
VAL B  52
ALA B  56
LEU B  58
 None
 0.74A 2m9qA-3u1jB:
6.6		 2m9qA-3u1jB:
55.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1j SERINE PROTEASE
SUBUNIT NS2B
SERINE PROTEASE NS3

(Dengue virus;
Dengue virus) 		PF01002
(Flavi_NS2B)
PF00949
(Peptidase_S7) 		5 LEU A  51
PHE B  46
VAL B  52
ALA B  56
LEU B  58
 None
 1.01A 2m9qA-3u1jA:
undetectable		 2m9qA-3u1jA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0l GLUCOKINASE

(Xenopus laevis) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		5 LEU A 342
ILE A 344
ILE A 331
VAL A 360
ALA A 352
 None
 1.16A 2m9qA-3w0lA:
undetectable		 2m9qA-3w0lA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zo9 TREHALOSE
SYNTHASE/AMYLASE
TRES

(Mycolicibacterium
smegmatis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		5 ILE A 224
ILE A 126
PHE A 111
ALA A 118
LEU A 115
 None
 1.18A 2m9qA-3zo9A:
undetectable		 2m9qA-3zo9A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a9a RIBOSOME-INTERACTING
GTPASE 1

(Saccharomyces
cerevisiae) 		PF01926
(MMR_HSR1)
PF02824
(TGS)
PF16897
(MMR_HSR1_Xtn) 		5 LEU A 201
ILE A 192
ILE A 220
ALA A 226
LEU A 198
 None
 1.05A 2m9qA-4a9aA:
undetectable		 2m9qA-4a9aA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3v TRANSCRIPTIONAL
REGULATOR NLH2

(Aquifex
aeolicus) 		PF13185
(GAF_2) 		5 LEU A  40
ILE A 132
ILE A 116
THR A 148
LEU A  36
 None
 1.08A 2m9qA-4g3vA:
undetectable		 2m9qA-4g3vA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyp GLUCARATE
DEHYDRATASE-RELATED
PROTEIN

(Escherichia
coli) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 LEU C 382
ILE C 384
THR C 366
THR C 351
ALA C 348
 None
 1.19A 2m9qA-4gypC:
undetectable		 2m9qA-4gypC:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN

(Eubacterium
ventriosum) 		PF13306
(LRR_5) 		5 ILE A  55
ILE A  43
PHE A  96
VAL A  39
LEU A  53
 None
 1.13A 2m9qA-4h09A:
undetectable		 2m9qA-4h09A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h41 PUTATIVE
ALPHA-L-FUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF14488
(DUF4434)
PF17134
(DUF5109) 		6 LEU A  58
ILE A  60
ILE A 335
THR A 298
ALA A 326
LEU A 323
 None
 1.20A 2m9qA-4h41A:
undetectable		 2m9qA-4h41A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j1x EPOXIDASE

(Streptomyces
wedmorensis) 		PF01381
(HTH_3)
PF07883
(Cupin_2) 		5 ILE A  59
PHE A  11
VAL A  40
THR A  39
LEU A  51
 None
 1.06A 2m9qA-4j1xA:
undetectable		 2m9qA-4j1xA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3f PROBABLE
TONB-DEPENDENT
RECEPTOR

(Pseudomonas
aeruginosa) 		PF03180
(Lipoprotein_9) 		5 LEU A 139
ILE A 146
VAL A 145
ALA A 208
LEU A 189
 None
 1.05A 2m9qA-4k3fA:
undetectable		 2m9qA-4k3fA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kh9 HYPOTHETICAL PROTEIN

(Legionella
pneumophila) 		PF16024
(DUF4785) 		5 LEU A 104
ILE A 106
ILE A  82
VAL A  91
ALA A 141
 None
 1.13A 2m9qA-4kh9A:
undetectable		 2m9qA-4kh9A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnv THIOESTER-CONTAINING
PROTEIN I

(Anopheles
gambiae) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		5 LEU A 661
ILE A 533
THR A 683
VAL A 652
ALA A 549
 None
 1.06A 2m9qA-4lnvA:
undetectable		 2m9qA-4lnvA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lp1 PROTEIN CYAY

(Psychromonas
ingrahamii) 		PF01491
(Frataxin_Cyay) 		6 ILE A  49
ILE A  48
PHE A  85
THR A  62
ALA A  92
LEU A  89
 None
 1.43A 2m9qA-4lp1A:
undetectable		 2m9qA-4lp1A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5a LACI FAMILY
TRANSCRIPTION
REGULATOR

(Bifidobacterium
animalis) 		PF13377
(Peripla_BP_3) 		5 LEU A 297
ILE A 279
ILE A 251
ALA A 175
LEU A 331
 None
 1.04A 2m9qA-4o5aA:
undetectable		 2m9qA-4o5aA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r27 GLYCOSIDE HYDROLASE

(Microbacterium
sp. Gsoil167) 		PF00232
(Glyco_hydro_1) 		6 LEU A  49
ILE A  53
PHE A 217
VAL A 195
ALA A 201
LEU A  46
 None
 1.27A 2m9qA-4r27A:
undetectable		 2m9qA-4r27A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7d ATP-DEPENDENT DNA
HELICASE Q1

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		5 ILE A 304
ILE A 301
VAL A 330
THR A 331
ALA A 341
 None
 1.05A 2m9qA-4u7dA:
undetectable		 2m9qA-4u7dA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uds MBDR REGULATOR

(Azoarcus sp.
CIB) 		PF00440
(TetR_N) 		5 ILE A  41
ILE A  38
PHE A  28
THR A  58
ALA A  61
 None
 1.17A 2m9qA-4udsA:
undetectable		 2m9qA-4udsA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v2d FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 2

(Homo sapiens) 		PF01463
(LRRCT)
PF13855
(LRR_8) 		5 ILE A 283
ILE A 267
PHE A 337
VAL A 295
LEU A 305
 None
 1.14A 2m9qA-4v2dA:
undetectable		 2m9qA-4v2dA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v2d FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 2

(Homo sapiens) 		PF01463
(LRRCT)
PF13855
(LRR_8) 		5 LEU A 281
ILE A 267
PHE A 337
VAL A 295
LEU A 305
 None
 1.14A 2m9qA-4v2dA:
undetectable		 2m9qA-4v2dA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z1p CELL WALL SURFACE
ANCHOR PROTEIN

(Streptococcus
agalactiae) 		PF16364
(Antigen_C) 		5 ILE A  98
ILE A 155
PHE A 109
THR A 113
LEU A  90
 None
 1.10A 2m9qA-4z1pA:
undetectable		 2m9qA-4z1pA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z1p CELL WALL SURFACE
ANCHOR PROTEIN

(Streptococcus
agalactiae) 		PF16364
(Antigen_C) 		5 LEU A  94
ILE A 155
PHE A 109
THR A 113
LEU A  90
 None
 1.15A 2m9qA-4z1pA:
undetectable		 2m9qA-4z1pA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zon VERRUCULOGEN
SYNTHASE

(Aspergillus
fumigatus) 		PF05721
(PhyH) 		5 LEU A 255
ILE A  91
PHE A 225
ALA A  79
LEU A 111
 None
 1.16A 2m9qA-4zonA:
undetectable		 2m9qA-4zonA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zze SUGAR BINDING
PROTEIN OF ABC
TRANSPORTER SYSTEM

(Bifidobacterium
animalis) 		PF01547
(SBP_bac_1) 		5 ILE A 403
ILE A 397
PHE A 419
ALA A 226
LEU A 222
 None
 1.10A 2m9qA-4zzeA:
undetectable		 2m9qA-4zzeA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dju NPH1-2
ENGINEERED PROTEIN,
ZDK3 AFFIBODY

(Avena sativa;
Staphylococcus
aureus) 		PF13426
(PAS_9)
PF02216
(B) 		5 ILE A 417
ILE A 510
PHE B  28
ALA A 542
LEU A 408
 None
 1.08A 2m9qA-5djuA:
undetectable		 2m9qA-5djuA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5du2 ESPG2
GLYCOSYLTRANSFERASE

(Actinomadura
verrucosospora) 		PF00201
(UDPGT) 		5 LEU A 290
VAL A 301
THR A 302
ALA A 308
LEU A 294
 None
 1.19A 2m9qA-5du2A:
undetectable		 2m9qA-5du2A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g39 PHOTOSYSTEM II
MANGANESE-STABILIZIN
G POLYPEPTIDE

(Thermosynechococcus
elongatus) 		PF01716
(MSP) 		5 ILE A 129
PHE A 135
THR A 122
VAL A 126
LEU A  78
 None
 1.14A 2m9qA-5g39A:
0.7		 2m9qA-5g39A:
22.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5gj4 SERINE PROTEASE NS3

(Zika virus) 		PF00949
(Peptidase_S7) 		5 PHE B  46
THR B  48
VAL B  52
ALA B  56
LEU B  58
 None
 0.70A 2m9qA-5gj4B:
12.9		 2m9qA-5gj4B:
46.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikp GLYCOGEN
PHOSPHORYLASE, BRAIN
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		5 ILE A 308
ILE A 307
PHE A 326
THR A 371
LEU A 353
 None
 1.17A 2m9qA-5ikpA:
undetectable		 2m9qA-5ikpA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ito NOPALINE-BINDING
PERIPLASMIC PROTEIN

(Agrobacterium
fabrum) 		PF00497
(SBP_bac_3) 		5 ILE A 258
ILE A 262
VAL A 267
THR A 266
LEU A  62
 None
 1.13A 2m9qA-5itoA:
undetectable		 2m9qA-5itoA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k47 POLYCYSTIN-2

(Homo sapiens) 		PF08016
(PKD_channel) 		5 ILE A 321
PHE A 279
THR A 283
VAL A 406
LEU A 415
 None
 1.14A 2m9qA-5k47A:
undetectable		 2m9qA-5k47A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kci UNCHARACTERIZED
PROTEIN YPL067C

(Saccharomyces
cerevisiae) 		PF12239
(DUF3605) 		5 LEU A 143
PHE A 195
VAL A 187
THR A 186
LEU A 140
 None
 1.11A 2m9qA-5kciA:
undetectable		 2m9qA-5kciA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l46 DIMETHYLGLYCINE
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		5 ILE A 278
PHE A 173
VAL A 358
ALA A 352
LEU A 300
 None
 0.92A 2m9qA-5l46A:
undetectable		 2m9qA-5l46A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		5 LEU A1345
ILE A1453
PHE A1291
VAL A1399
THR A1400
 None
 1.03A 2m9qA-5me3A:
undetectable		 2m9qA-5me3A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzh DYNEIN ASSEMBLY
FACTOR WITH WDR
REPEAT DOMAINS 1

(Chlamydomonas
reinhardtii) 		PF00400
(WD40) 		5 ILE A 415
ILE A 405
THR A 111
ALA A  92
LEU A  90
 None
 1.13A 2m9qA-5mzhA:
undetectable		 2m9qA-5mzhA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nkm PROTEIN SMG-9

(Caenorhabditis
elegans) 		no annotation 5 ILE D 207
ILE D 206
PHE D 263
VAL D 196
LEU D 259
 None
 1.14A 2m9qA-5nkmD:
undetectable		 2m9qA-5nkmD:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc0 CYTOCHROME B561

(Escherichia
coli) 		no annotation 5 LEU A  97
ILE A  52
VAL A  20
ALA A 141
LEU A  93
 HEM  A 202 (-4.4A)
HEM  A 202 ( 3.8A)
None
HEM  A 202 (-3.5A)
None
 1.12A 2m9qA-5oc0A:
undetectable		 2m9qA-5oc0A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5t1v NS2B-NS3
PROTEASE,NS2B-NS3
PROTEASE

(Zika virus) 		PF00949
(Peptidase_S7)
PF01002
(Flavi_NS2B) 		5 PHE A 111
THR A 113
VAL A 117
ALA A 121
LEU A 123
 None
 0.70A 2m9qA-5t1vA:
13.1		 2m9qA-5t1vA:
48.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhj GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE

(Streptomyces
sp. CB03234) 		PF00903
(Glyoxalase) 		5 ILE A  53
ILE A   8
PHE A 119
THR A  72
LEU A  76
 None
 1.18A 2m9qA-5uhjA:
undetectable		 2m9qA-5uhjA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ulu CADHERIN-23

(Mus musculus) 		no annotation 5 LEU A2256
ILE A2188
PHE A2151
VAL A2210
ALA A2171
 None
 0.82A 2m9qA-5uluA:
undetectable		 2m9qA-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5umq GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE

(Streptomyces
sp. CB03234) 		no annotation 5 ILE A  53
ILE A   8
PHE A 119
THR A  72
LEU A  76
 None
 1.18A 2m9qA-5umqA:
undetectable		 2m9qA-5umqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vdn GLUTATHIONE
OXIDOREDUCTASE

(Yersinia pestis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 ILE A 147
ILE A 295
PHE A 127
THR A 285
LEU A 280
 None
None
None
None
FAD  A 502 ( 4.2A)
 1.07A 2m9qA-5vdnA:
undetectable		 2m9qA-5vdnA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wg6 HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2,POLYCOMB
PROTEIN SUZ12
(E.C.2.1.1.43)
CHIMERA

(Homo sapiens) 		no annotation 5 ILE A2674
ILE A2671
THR A 446
ALA A 453
LEU A 457
 None
 0.90A 2m9qA-5wg6A:
undetectable		 2m9qA-5wg6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhw PUTATIVE
6-DEOXY-D-MANNOHEPTO
SE PATHWAY PROTEIN

(Yersinia
pseudotuberculosis) 		no annotation 5 LEU A  54
ILE A  78
ILE A  51
VAL A   5
ALA A   8
 None
 1.01A 2m9qA-5xhwA:
undetectable		 2m9qA-5xhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmg UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		no annotation 5 ILE A 337
VAL A 335
THR A 327
ALA A 301
LEU A 294
 None
 1.11A 2m9qA-5xmgA:
undetectable		 2m9qA-5xmgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y28 -

(-) 		no annotation 5 ILE A 226
ILE A 178
VAL A 188
THR A 189
ALA A 214
 None
 1.09A 2m9qA-5y28A:
6.3		 2m9qA-5y28A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2d -

(-) 		no annotation 5 ILE A 226
ILE A 178
VAL A 188
THR A 189
ALA A 214
 None
 1.13A 2m9qA-5y2dA:
1.1		 2m9qA-5y2dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2d -

(-) 		no annotation 5 LEU A 225
ILE A 226
ILE A 178
VAL A 188
ALA A 214
 None
 1.14A 2m9qA-5y2dA:
1.1		 2m9qA-5y2dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y30 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 5 LEU A  96
ILE A  82
PHE A 135
THR A 134
LEU A 120
 None
 1.11A 2m9qA-5y30A:
undetectable		 2m9qA-5y30A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y30 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 5 LEU A  96
ILE A 122
PHE A 135
THR A 134
LEU A 120
 None
 1.15A 2m9qA-5y30A:
undetectable		 2m9qA-5y30A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 5 LEU B  96
ILE B  82
PHE B 135
THR B 134
LEU B 120
 None
 1.10A 2m9qA-5y31B:
undetectable		 2m9qA-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 5 LEU B  96
ILE B 122
PHE B 135
THR B 134
LEU B 120
 None
 1.15A 2m9qA-5y31B:
undetectable		 2m9qA-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4o GLUTATHIONE
REDUCTASE

(Enterococcus
faecalis) 		no annotation 5 LEU A 135
ILE A 297
PHE A 116
VAL A 284
ALA A 137
 None
None
None
None
FAD  A 501 (-4.8A)
 1.04A 2m9qA-6b4oA:
undetectable		 2m9qA-6b4oA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6l V-TYPE PROTON ATPASE
SUBUNIT A, VACUOLAR
ISOFORM

(Saccharomyces
cerevisiae) 		no annotation 5 LEU A 586
ILE A 582
PHE A 616
VAL A 727
LEU A 612
 None
 1.15A 2m9qA-6c6lA:
undetectable		 2m9qA-6c6lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6l V-TYPE PROTON ATPASE
SUBUNIT A, VACUOLAR
ISOFORM
V-TYPE PROTON ATPASE
SUBUNIT F

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		no annotation
no annotation 		5 LEU O  24
ILE A 755
PHE O  31
THR A 770
ALA O  58
 None
 1.05A 2m9qA-6c6lO:
undetectable		 2m9qA-6c6lO:
undetectable