SIMILAR PATTERNS OF AMINO ACIDS FOR 2M2O_B_DHIB24
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bjx | PROTEIN DISULFIDEISOMERASE (Homo sapiens) |
PF13848(Thioredoxin_6) | 4 | GLY A 142PHE A 155LYS A 119THR A 121 | None | 1.01A | 2m2oB-1bjxA:undetectable | 2m2oB-1bjxA:10.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bu8 | PROTEIN (PANCREATICLIPASE RELATEDPROTEIN 2) (Rattusnorvegicus) |
PF00151(Lipase)PF01477(PLAT) | 4 | ARG A 164GLY A 125PRO A 31THR A 36 | None | 1.12A | 2m2oB-1bu8A:undetectable | 2m2oB-1bu8A:7.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwv | INVASIN (Yersiniapseudotuberculosis) |
PF02369(Big_1)PF07979(Intimin_C)PF09134(Invasin_D3) | 4 | ARG A 926GLY A 934LYS A 816THR A 817 | None | 1.11A | 2m2oB-1cwvA:undetectable | 2m2oB-1cwvA:5.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwv | INVASIN (Yersiniapseudotuberculosis) |
PF02369(Big_1)PF07979(Intimin_C)PF09134(Invasin_D3) | 4 | ARG A 926PRO A 815LYS A 816THR A 817 | None | 1.24A | 2m2oB-1cwvA:undetectable | 2m2oB-1cwvA:5.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1czv | PROTEIN (COAGULATIONFACTOR V) (Homo sapiens) |
PF00754(F5_F8_type_C) | 4 | GLY A 115PRO A 140LYS A 141THR A 142 | None | 0.96A | 2m2oB-1czvA:undetectable | 2m2oB-1czvA:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f6y | 5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE (Moorellathermoacetica) |
PF00809(Pterin_bind) | 4 | GLY A 121PRO A 191LYS A 192THR A 193 | None | 1.32A | 2m2oB-1f6yA:undetectable | 2m2oB-1f6yA:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpl | LIPASE (Equus caballus) |
PF00151(Lipase)PF01477(PLAT) | 4 | ARG A 164GLY A 125PRO A 31THR A 36 | None | 1.15A | 2m2oB-1hplA:undetectable | 2m2oB-1hplA:5.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ktw | IOTA-CARRAGEENASE (Alteromonas sp.ATCC 43554) |
PF12708(Pectate_lyase_3) | 4 | ARG A 243GLY A 219LYS A 181THR A 182 | DGS A 492 (-3.1A)NoneNone NA A 11 (-3.5A) | 1.32A | 2m2oB-1ktwA:undetectable | 2m2oB-1ktwA:5.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lrw | METHANOLDEHYDROGENASESUBUNIT 1 (Paracoccusdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | ARG A 99PHE A 71PRO A 70THR A 74 | None | 1.17A | 2m2oB-1lrwA:undetectable | 2m2oB-1lrwA:3.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhm | S-ADENOSYLMETHIONINEDECARBOXYLASE (Solanumtuberosum) |
PF01536(SAM_decarbox) | 4 | GLY A 265PRO A 268LYS A 269THR A 270 | None | 1.37A | 2m2oB-1mhmA:undetectable | 2m2oB-1mhmA:9.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sdd | COAGULATION FACTOR V (Bos taurus) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 4 | GLY B2139PRO B2164LYS B2165THR B2166 | None | 0.70A | 2m2oB-1sddB:undetectable | 2m2oB-1sddB:3.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v02 | DHURRINASE (Sorghum bicolor) |
PF00232(Glyco_hydro_1) | 4 | ARG A 426GLY A 408PHE A 469THR A 466 | None | 1.35A | 2m2oB-1v02A:undetectable | 2m2oB-1v02A:5.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1k | VANILLYL-ALCOHOLOXIDASE (Penicilliumsimplicissimum) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 4 | ARG A 211GLY A 215LYS A 237THR A 238 | None | 1.31A | 2m2oB-1w1kA:undetectable | 2m2oB-1w1kA:9.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xp4 | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Streptococcuspneumoniae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 4 | GLY A 252PHE A 235LYS A 207THR A 206 | None | 1.19A | 2m2oB-1xp4A:undetectable | 2m2oB-1xp4A:8.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yf2 | TYPE IRESTRICTION-MODIFICATION ENZYME, SSUBUNIT (Methanocaldococcusjannaschii) |
PF01420(Methylase_S) | 4 | GLY A 242PHE A 320PRO A 263THR A 304 | None | 1.10A | 2m2oB-1yf2A:undetectable | 2m2oB-1yf2A:5.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 4 | ARG A 12GLY A 9PHE A 8PRO A 6 | None | 1.23A | 2m2oB-1ygpA:undetectable | 2m2oB-1ygpA:2.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1f | THREONINE SYNTHASE (Mycobacteriumtuberculosis) |
PF00291(PALP) | 4 | ARG A 169GLY A 72LYS A 174THR A 175 | None | 1.14A | 2m2oB-2d1fA:undetectable | 2m2oB-2d1fA:6.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g29 | NITRATE TRANSPORTPROTEIN NRTA (Synechocystissp.) |
PF13379(NMT1_2) | 4 | ARG A 106GLY A 103PRO A 192THR A 190 | NoneNoneNoneNO3 A 700 (-3.9A) | 1.37A | 2m2oB-2g29A:undetectable | 2m2oB-2g29A:5.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h4t | CARNITINEO-PALMITOYLTRANSFERASE II, MITOCHONDRIAL (Rattusnorvegicus) |
PF00755(Carn_acyltransf) | 4 | ARG A 63GLY A 551PRO A 53THR A 491 | None | 1.01A | 2m2oB-2h4tA:undetectable | 2m2oB-2h4tA:5.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuk | SEED LIPOXYGENASE (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | GLY A 223PRO A 258LYS A 257THR A 249 | None | 1.37A | 2m2oB-2iukA:undetectable | 2m2oB-2iukA:4.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jss | CHIMERA OF HISTONEH2B.1 AND HISTONEH2A.Z (Saccharomycescerevisiae) |
PF00125(Histone)PF16211(Histone_H2A_C) | 4 | GLY A 149PRO A 18LYS A 14THR A 16 | None | 1.26A | 2m2oB-2jssA:undetectable | 2m2oB-2jssA:11.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jxm | CYTOCHROME F (Prochlorothrixhollandica) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 4 | GLY B 153PHE B 236LYS B 29THR B 30 | NoneHEC B 250 ( 4.9A)NoneNone | 1.35A | 2m2oB-2jxmB:undetectable | 2m2oB-2jxmB:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ope | PILX (Neisseriameningitidis) |
PF11530(Pilin_PilX) | 4 | GLY A 109PRO A 104LYS A 105THR A 106 | None | 1.13A | 2m2oB-2opeA:undetectable | 2m2oB-2opeA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oze | ORF DELTA' (Streptococcuspyogenes) |
PF13614(AAA_31) | 4 | ARG A 289GLY A 216PHE A 247PRO A 219 | None | 1.37A | 2m2oB-2ozeA:undetectable | 2m2oB-2ozeA:7.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qz6 | BETA-LACTAMASE (Pseudomonasfluorescens) |
PF00144(Beta-lactamase) | 4 | GLY A 116PHE A 142PRO A 144THR A 113 | None | 1.13A | 2m2oB-2qz6A:undetectable | 2m2oB-2qz6A:6.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x7j | 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE-1-CARBOXYLATESYNTHASE (Bacillussubtilis) |
PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N)PF16582(TPP_enzyme_M_2) | 4 | ARG A 388GLY A 384PHE A 382THR A 554 | None | 1.31A | 2m2oB-2x7jA:undetectable | 2m2oB-2x7jA:4.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsj | THREONINE SYNTHASE (Aquifexaeolicus) |
PF00291(PALP) | 4 | ARG A 162GLY A 66LYS A 167THR A 168 | None | 1.24A | 2m2oB-2zsjA:undetectable | 2m2oB-2zsjA:6.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a14 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Thermotogamaritima) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 4 | ARG A 332GLY A 329PRO A 291THR A 202 | None | 1.29A | 2m2oB-3a14A:undetectable | 2m2oB-3a14A:5.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axx | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 4 | GLY A 221PRO A 259LYS A 260THR A 261 | None | 1.31A | 2m2oB-3axxA:undetectable | 2m2oB-3axxA:6.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bkh | LYTICTRANSGLYCOSYLASE (Pseudomonasvirus phiKZ) |
PF01464(SLT)PF01471(PG_binding_1) | 4 | PHE A 234PRO A 241LYS A 242THR A 243 | None | 1.21A | 2m2oB-3bkhA:undetectable | 2m2oB-3bkhA:6.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bn6 | LACTADHERIN (Bos taurus) |
PF00754(F5_F8_type_C) | 4 | ARG A 136GLY A 65PRO A 13THR A 11 | None | 1.23A | 2m2oB-3bn6A:undetectable | 2m2oB-3bn6A:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckz | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | ARG A 300GLY A 323PRO A 326THR A 368 | None | 1.28A | 2m2oB-3ckzA:undetectable | 2m2oB-3ckzA:6.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egw | RESPIRATORY NITRATEREDUCTASE 1 BETACHAIN (Escherichiacoli) |
PF13247(Fer4_11)PF14711(Nitr_red_bet_C) | 4 | GLY B 149PRO B 48LYS B 47THR B 46 | None | 1.28A | 2m2oB-3egwB:undetectable | 2m2oB-3egwB:5.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3emy | TRICHODERMA REESEIASPARTIC PROTEASE (Trichodermareesei) |
PF00026(Asp) | 4 | GLY A 285PHE A 284PRO A 277THR A 282 | None | 1.27A | 2m2oB-3emyA:undetectable | 2m2oB-3emyA:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eo7 | PUTATIVENITROREDUCTASE (Trichormusvariabilis) |
PF00881(Nitroreductase) | 4 | GLY A 482PHE A 483LYS A 17THR A 16 | NoneNonePGR A 716 ( 4.7A)None | 1.34A | 2m2oB-3eo7A:undetectable | 2m2oB-3eo7A:6.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gde | DNA LIGASE (Archaeoglobusfulgidus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | GLY A 431PHE A 494PRO A 496LYS A 497 | None | 1.06A | 2m2oB-3gdeA:undetectable | 2m2oB-3gdeA:4.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdy | UDP-GALACTOPYRANOSEMUTASE (Deinococcusradiodurans) |
PF03275(GLF)PF13450(NAD_binding_8) | 4 | ARG A 244PHE A 264PRO A 260THR A 258 | FAD A 450 ( 3.9A)NoneNoneNone | 1.25A | 2m2oB-3hdyA:undetectable | 2m2oB-3hdyA:7.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j93 | NEUTRALIZINGANTIBODY 22A12,HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY H 119PRO H 12LYS H 11THR H 116 | None | 1.23A | 2m2oB-3j93H:undetectable | 2m2oB-3j93H:7.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jxz | ALKYLPURINE DNAGLYCOSYLASE ALKD (Bacillus cereus) |
PF08713(DNA_alkylation) | 4 | ARG A 66PHE A 98PRO A 97THR A 94 | None | 1.00A | 2m2oB-3jxzA:undetectable | 2m2oB-3jxzA:8.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kci | PROBABLE E3UBIQUITIN-PROTEINLIGASE HERC2 (Homo sapiens) |
PF00415(RCC1) | 4 | GLY A4116PRO A4134LYS A4135THR A4114 | None | 1.16A | 2m2oB-3kciA:undetectable | 2m2oB-3kciA:6.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kke | LACI FAMILYTRANSCRIPTIONALREGULATOR (Mycolicibacteriumsmegmatis) |
PF13377(Peripla_BP_3) | 4 | ARG A 195GLY A 164PRO A 297THR A 327 | ACT A 1 (-2.7A)NoneNoneNone | 1.21A | 2m2oB-3kkeA:undetectable | 2m2oB-3kkeA:6.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lif | PUTATIVE DIGUANYLATECYCLASE (GGDEF) WITHPAS/PAC DOMAIN (Rhodopseudomonaspalustris) |
PF02743(dCache_1) | 4 | ARG A 216GLY A 155PHE A 167THR A 187 | NoneNoneNoneMPD A 1 ( 4.6A) | 1.28A | 2m2oB-3lifA:undetectable | 2m2oB-3lifA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1u | PUTATIVEGAMMA-D-GLUTAMYL-L-DIAMINO ACIDENDOPEPTIDASE (Desulfovibriovulgaris) |
PF00877(NLPC_P60)PF12912(N_NLPC_P60)PF12913(SH3_6)PF12914(SH3_7) | 4 | ARG A 452GLY A 451PRO A 436THR A 434 | CL A 23 ( 3.1A)NoneNoneNone | 1.29A | 2m2oB-3m1uA:undetectable | 2m2oB-3m1uA:7.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m8y | PHOSPHOPENTOMUTASE (Bacillus cereus) |
PF01676(Metalloenzyme) | 4 | GLY A 53PRO A 345LYS A 75THR A 74 | NoneNoneACT A 399 ( 4.6A)ACT A 399 (-4.3A) | 1.31A | 2m2oB-3m8yA:undetectable | 2m2oB-3m8yA:4.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mtv | PAPAIN-LIKE CYSTEINEPROTEASE (Porcinereproductiveand respiratorysyndrome virus) |
PF05411(Peptidase_C32) | 4 | GLY A 170PHE A 150PRO A 86THR A 84 | None | 1.17A | 2m2oB-3mtvA:undetectable | 2m2oB-3mtvA:9.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pnz | PHOSPHOTRIESTERASEFAMILY PROTEIN (Listeriamonocytogenes) |
PF02126(PTE) | 4 | ARG A 218GLY A 191LYS A 155THR A 157 | NoneNoneKCX A 154 ( 3.5A)None | 1.01A | 2m2oB-3pnzA:undetectable | 2m2oB-3pnzA:6.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r50 | IPOMOELIN (Ipomoea batatas) |
PF01419(Jacalin) | 4 | GLY A 116PHE A 39PRO A 43THR A 46 | None | 1.25A | 2m2oB-3r50A:undetectable | 2m2oB-3r50A:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rdv | CAP-GLYDOMAIN-CONTAININGLINKER PROTEIN 1 (Homo sapiens) |
PF01302(CAP_GLY) | 4 | ARG A 107GLY A 101PRO A 113LYS A 115 | None | 1.19A | 2m2oB-3rdvA:undetectable | 2m2oB-3rdvA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3th1 | CHLOROCATECHOL1,2-DIOXYGENASE (Pseudomonasputida) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 4 | ARG A 246GLY A 197PHE A 198PRO A 200 | None | 1.08A | 2m2oB-3th1A:undetectable | 2m2oB-3th1A:11.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ue9 | ADENYLOSUCCINATESYNTHETASE (Burkholderiathailandensis) |
PF00709(Adenylsucc_synt) | 4 | ARG A 42GLY A 232PHE A 43THR A 236 | None | 1.01A | 2m2oB-3ue9A:undetectable | 2m2oB-3ue9A:4.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ve2 | TRANSFERRIN-BINDINGPROTEIN 2 (Neisseriameningitidis) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | GLY A 249PRO A 175LYS A 377THR A 379 | None | 1.27A | 2m2oB-3ve2A:undetectable | 2m2oB-3ve2A:4.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vkg | DYNEIN HEAVY CHAIN,CYTOPLASMIC (Dictyosteliumdiscoideum) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | GLY A1743PHE A1754PRO A1757THR A1740 | None | 1.35A | 2m2oB-3vkgA:undetectable | 2m2oB-3vkgA:1.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w6m | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 4 | GLY A 221PRO A 259LYS A 260THR A 261 | NoneGOL A 501 (-4.1A)NoneNone | 1.08A | 2m2oB-3w6mA:undetectable | 2m2oB-3w6mA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zz1 | BETA-D-GLUCOSIDEGLUCOHYDROLASE (Trichodermareesei) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | ARG A 291GLY A 231PHE A 229PRO A 604 | None | 1.00A | 2m2oB-3zz1A:undetectable | 2m2oB-3zz1A:3.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aip | FE-REGULATED PROTEINB (Neisseriameningitidis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | ARG A 86GLY A 98PRO A 728THR A 726 | None | 1.02A | 2m2oB-4aipA:undetectable | 2m2oB-4aipA:2.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bs9 | TRUD (unculturedProchloron sp.06037A) |
PF02624(YcaO) | 4 | ARG A 123PRO A 191LYS A 190THR A 164 | None | 1.35A | 2m2oB-4bs9A:undetectable | 2m2oB-4bs9A:3.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 4 | GLY V1386PHE V1359PRO V1411THR V1413 | None | 1.21A | 2m2oB-4bxsV:undetectable | 2m2oB-4bxsV:2.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dq8 | ACETATE KINASE (Mycobacteriummarinum) |
PF00871(Acetate_kinase) | 4 | ARG A 328GLY A 321PRO A 370THR A 371 | None | 1.26A | 2m2oB-4dq8A:undetectable | 2m2oB-4dq8A:5.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvj | PUTATIVEZINC-DEPENDENTALCOHOLDEHYDROGENASEPROTEIN (Rhizobium etli) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 4 | GLY A 320PRO A 136LYS A 137THR A 138 | None | 1.27A | 2m2oB-4dvjA:undetectable | 2m2oB-4dvjA:6.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fze | N26_I1 FAB HEAVYCHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY H 50PHE H 33PRO H 52THR H 56 | None | 1.03A | 2m2oB-4fzeH:undetectable | 2m2oB-4fzeH:9.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h0p | ACETATE KINASE (Cryptococcusneoformans) |
PF00871(Acetate_kinase) | 4 | ARG A 164GLY A 105PRO A 185THR A 183 | None | 0.92A | 2m2oB-4h0pA:undetectable | 2m2oB-4h0pA:11.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hfo | BIOGENICAMINE-BINDINGPROTEIN (Rhodniusprolixus) |
PF02087(Nitrophorin) | 4 | GLY A 38PRO A 64LYS A 67THR A 68 | None | 0.95A | 2m2oB-4hfoA:undetectable | 2m2oB-4hfoA:8.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hz8 | BETA-GLUCOSIDASE (unculturedbacterium) |
PF00232(Glyco_hydro_1) | 4 | GLY A 430PHE A 47LYS A 111THR A 112 | None | 1.31A | 2m2oB-4hz8A:undetectable | 2m2oB-4hz8A:5.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iss | ALLOPHANATEHYDROLASE (Kluyveromyceslactis) |
PF01425(Amidase) | 4 | GLY A 579PRO A 513LYS A 514THR A 515 | None | 1.21A | 2m2oB-4issA:undetectable | 2m2oB-4issA:3.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ka8 | OLIGOPEPTIDASE A (Arabidopsisthaliana) |
PF01432(Peptidase_M3) | 4 | GLY A 518PRO A 513LYS A 269THR A 268 | None | 1.20A | 2m2oB-4ka8A:undetectable | 2m2oB-4ka8A:4.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kc8 | GLYCOSIDE HYDROLASE,FAMILY 43 (Thermotogapetrophila) |
PF04616(Glyco_hydro_43)PF16369(GH43_C) | 4 | ARG A 337GLY A 336PHE A 304THR A 301 | None | 1.30A | 2m2oB-4kc8A:undetectable | 2m2oB-4kc8A:7.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4my0 | GCN5-RELATEDN-ACETYLTRANSFERASE (Kribbellaflavida) |
PF13527(Acetyltransf_9)PF13530(SCP2_2) | 4 | ARG A 291GLY A 292PHE A 293PRO A 295 | None | 1.32A | 2m2oB-4my0A:undetectable | 2m2oB-4my0A:6.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nqq | CADHERIN-3 (Mus musculus) |
PF00028(Cadherin) | 4 | GLY A 144PRO A 106LYS A 107THR A 133 | CA A 303 ( 4.7A)NoneNoneNone | 1.24A | 2m2oB-4nqqA:undetectable | 2m2oB-4nqqA:10.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | GLY A 156PRO A 180LYS A 181THR A 182 | None | 1.03A | 2m2oB-4o9xA:undetectable | 2m2oB-4o9xA:2.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ohs | FAR-RED FLUORESCENTPROTEIN AQ143 (Actinia equina) |
PF01353(GFP) | 4 | ARG A 181GLY A 87LYS A 67THR A 68 | NoneNoneCH6 A 63 ( 4.0A)None | 1.10A | 2m2oB-4ohsA:undetectable | 2m2oB-4ohsA:7.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4or5 | PROTEIN TATAF4/FMR2 FAMILYMEMBER 4 (Humanimmunodeficiencyvirus 1;Homo sapiens) |
PF00539(Tat)PF05110(AF-4) | 4 | GLY E 67PRO C 18LYS C 19THR C 20 | None | 1.03A | 2m2oB-4or5E:undetectable | 2m2oB-4or5E:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4orb | SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITALPHA ISOFORM (Mus musculus) |
PF00149(Metallophos) | 4 | ARG A 292GLY A 240LYS A 243THR A 244 | None | 1.36A | 2m2oB-4orbA:undetectable | 2m2oB-4orbA:6.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qww | ACETYLCHOLINESTERASE (Bungarusfasciatus) |
PF00135(COesterase) | 4 | ARG A 221GLY A 480PHE A 476THR A 483 | None | 1.30A | 2m2oB-4qwwA:undetectable | 2m2oB-4qwwA:4.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv7 | DIADENYLATE CYCLASE (Listeriamonocytogenes) |
PF02457(DisA_N) | 4 | ARG A 103PHE A 63PRO A 65THR A 67 | ATP A1001 (-3.5A)NoneNoneNone | 1.35A | 2m2oB-4rv7A:undetectable | 2m2oB-4rv7A:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wtv | PHOSPHATIDYLINOSITOL4-KINASE TYPE2-BETA,ENDOLYSIN,PHOSPHATIDYLINOSITOL4-KINASE TYPE 2-BETA (Homo sapiens;Escherichiavirus T4) |
PF00454(PI3_PI4_kinase)PF00959(Phage_lysozyme) | 4 | GLY A 145PRO A 205LYS A 206THR A 207 | NoneATP A1201 ( 4.5A)NoneNone | 1.31A | 2m2oB-4wtvA:undetectable | 2m2oB-4wtvA:5.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yhb | IRON-CHELATORUTILIZATION PROTEIN (Thermobifidafusca) |
PF04954(SIP)PF08021(FAD_binding_9) | 4 | ARG A 87GLY A 113PHE A 58PRO A 61 | FAD A 301 (-3.8A)FAD A 301 (-3.6A)NoneNone | 0.90A | 2m2oB-4yhbA:undetectable | 2m2oB-4yhbA:9.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zrx | F5/8 TYPE C DOMAINPROTEIN (Bacteroidesovatus) |
PF00754(F5_F8_type_C)PF01120(Alpha_L_fucos) | 4 | ARG A 496GLY A 600PRO A 566THR A 568 | None | 1.26A | 2m2oB-4zrxA:undetectable | 2m2oB-4zrxA:4.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bxp | LACTO-N-BIOSIDASE (Bifidobacteriumbifidum) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b)PF14200(RicinB_lectin_2) | 4 | GLY A 149PRO A 177LYS A 176THR A 175 | None | 1.37A | 2m2oB-5bxpA:undetectable | 2m2oB-5bxpA:6.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fie | CELL SURFACE PROTEINSPAA (Lactobacillusrhamnosus) |
no annotation | 4 | GLY A 67PRO A 72LYS A 47THR A 46 | None | 1.15A | 2m2oB-5fieA:undetectable | 2m2oB-5fieA:10.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fji | BETA-GLUCOSIDASE (Aspergillusfumigatus) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | ARG A 337GLY A 276PHE A 274PRO A 755 | None | 1.02A | 2m2oB-5fjiA:undetectable | 2m2oB-5fjiA:3.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ghf | AMINOTRANSFERASECLASS-III (Ochrobactrumanthropi) |
PF00202(Aminotran_3) | 4 | ARG A 202PRO A 237LYS A 238THR A 239 | None | 1.26A | 2m2oB-5ghfA:undetectable | 2m2oB-5ghfA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gkq | ALYGC MUTANT - R241A (Paraglaciecolachathamensis) |
PF14592(Chondroitinas_B) | 4 | ARG A 627GLY A 636PRO A 691LYS A 692 | None | 1.23A | 2m2oB-5gkqA:undetectable | 2m2oB-5gkqA:4.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdl | CELL SURFACE PROTEINSPAA (Lactobacillusrhamnosus) |
no annotation | 4 | GLY A 67PRO A 72LYS A 47THR A 46 | None | 1.04A | 2m2oB-5hdlA:undetectable | 2m2oB-5hdlA:7.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzv | MALTOSE-BINDINGPERIPLASMICPROTEIN,ENDOGLIN (Escherichiacoli;Homo sapiens) |
PF00100(Zona_pellucida)PF13416(SBP_bac_8) | 4 | GLY A 898PRO A 942LYS A 943THR A 944 | None | 0.89A | 2m2oB-5hzvA:undetectable | 2m2oB-5hzvA:4.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i4a | ARGONAUTE PROTEIN (Marinitogapiezophila) |
no annotation | 4 | GLY A 233PRO A 238LYS A 239THR A 240 | None | 1.24A | 2m2oB-5i4aA:undetectable | 2m2oB-5i4aA:4.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | GLY A 579PRO A 513LYS A 514THR A 515 | None | 1.21A | 2m2oB-5i8iA:undetectable | 2m2oB-5i8iA:2.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i92 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Pseudomonasaeruginosa) |
PF00202(Aminotran_3) | 4 | GLY A 140PHE A 368PRO A 180THR A 178 | None | 1.27A | 2m2oB-5i92A:undetectable | 2m2oB-5i92A:5.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ju6 | BETA-GLUCOSIDASE (Rasamsoniaemersonii) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | ARG A 333GLY A 272PHE A 270PRO A 747 | None | 1.00A | 2m2oB-5ju6A:undetectable | 2m2oB-5ju6A:3.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mlc | 50S RIBOSOMALPROTEIN L29,CHLOROPLASTIC (Spinaciaoleracea) |
PF00831(Ribosomal_L29) | 4 | ARG Z 109GLY Z 106PRO Z 102LYS Z 101 | A A 59 ( 3.0A)None A A 94 ( 3.7A)None | 1.22A | 2m2oB-5mlcZ:undetectable | 2m2oB-5mlcZ:8.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nbs | BETA-GLUCOSIDASE (Neurosporacrassa) |
no annotation | 4 | ARG A 332GLY A 271PHE A 269PRO A 752 | None | 1.02A | 2m2oB-5nbsA:undetectable | 2m2oB-5nbsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5the | UNCHARACTERIZEDPROTEIN (Vanderwaltozymapolyspora) |
no annotation | 4 | GLY A 832PHE A 831PRO A 871THR A 869 | None | 1.19A | 2m2oB-5theA:undetectable | 2m2oB-5theA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2i | NUCLEOSIDEDIPHOSPHATE KINASE (Naegleriafowleri) |
PF00334(NDK) | 4 | GLY A 112PRO A 95LYS A 94THR A 93 | None | 1.02A | 2m2oB-5u2iA:undetectable | 2m2oB-5u2iA:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9c | DTDP-4-DEHYDRORHAMNOSE REDUCTASE (Yersiniaenterocolitica) |
PF04321(RmlD_sub_bind) | 4 | GLY A 95PRO A 54LYS A 53THR A 50 | None | 1.37A | 2m2oB-5u9cA:undetectable | 2m2oB-5u9cA:9.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v7q | 50S RIBOSOMALPROTEIN L4 (Mycobacteriumtuberculosis) |
PF00573(Ribosomal_L4) | 4 | ARG E 52GLY E 54PRO E 99LYS E 100 | C A 533 ( 3.6A)None G A1379 ( 4.0A) G A 798 ( 2.6A) | 1.31A | 2m2oB-5v7qE:undetectable | 2m2oB-5v7qE:10.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x8t | 50S RIBOSOMALPROTEIN L4,CHLOROPLASTIC (Spinaciaoleracea) |
PF00573(Ribosomal_L4) | 4 | PHE E 182PRO E 185LYS E 186THR E 187 | NoneNoneNone C A 329 ( 3.4A) | 1.22A | 2m2oB-5x8tE:undetectable | 2m2oB-5x8tE:7.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfm | ALPHA-GLUCOSIDASE (Bacteroidesthetaiotaomicron) |
no annotation | 4 | GLY A 439PRO A 176LYS A 175THR A 174 | CA A 701 ( 4.6A)NoneNoneNone | 1.31A | 2m2oB-5xfmA:undetectable | 2m2oB-5xfmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b0k | IOTA-CARRAGEENANSULFATASE (Pseudoalteromonas) |
no annotation | 4 | ARG A 254GLY A 299PRO A 232THR A 234 | NoneNoneNone9RN A 502 ( 3.3A) | 1.06A | 2m2oB-6b0kA:undetectable | 2m2oB-6b0kA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3o | SPIKE GLYCOPROTEIN (Murinecoronavirus) |
PF01601(Corona_S2) | 4 | GLY A1157PHE A1155PRO A1141LYS A1142 | None | 1.29A | 2m2oB-6b3oA:undetectable | 2m2oB-6b3oA:4.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c7s | PUTATIVE RIFAMPINMONOOXYGENASE (Nocardiafarcinica) |
no annotation | 4 | ARG A 196GLY A 203PHE A 202PRO A 217 | RFH A 502 (-3.1A)RFH A 502 (-3.6A)NoneNone | 1.33A | 2m2oB-6c7sA:undetectable | 2m2oB-6c7sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cj7 | SERPIN-12 (Manduca sexta) |
no annotation | 4 | GLY A 183PRO A 346LYS A 345THR A 180 | None | 1.27A | 2m2oB-6cj7A:undetectable | 2m2oB-6cj7A:undetectable |