SIMILAR PATTERNS OF AMINO ACIDS FOR 2LH6_A_NIOA155_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot virus) 		PF03391
(Nepo_coat)
PF03688
(Nepo_coat_C)
PF03689
(Nepo_coat_N) 		4 PHE A  16
PHE A 106
HIS A 114
VAL A 160
 None
 1.21A 2lh6A-1a6cA:
undetectable		 2lh6A-1a6cA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bsl BACTERIAL LUCIFERASE

(Vibrio harveyi) 		PF00296
(Bac_luciferase) 		4 PHE A 125
PHE A 128
PHE A 105
HIS A 132
 None
 1.23A 2lh6A-1bslA:
0.0		 2lh6A-1bslA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cbg CYANOGENIC
BETA-GLUCOSIDASE

(Trifolium
repens) 		PF00232
(Glyco_hydro_1) 		4 PHE A  23
PHE A  25
PHE A 487
VAL A 430
 None
 1.19A 2lh6A-1cbgA:
0.9		 2lh6A-1cbgA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cov COXSACKIEVIRUS COAT
PROTEIN

(Enterovirus B) 		PF00073
(Rhv) 		4 PHE 3  95
PHE 3  85
PHE 3  83
VAL 3 214
 None
 1.05A 2lh6A-1cov3:
undetectable		 2lh6A-1cov3:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cyn PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
B

(Homo sapiens) 		PF00160
(Pro_isomerase) 		4 PHE A  44
PHE A 120
PHE A  61
VAL A  14
 None
 1.26A 2lh6A-1cynA:
undetectable		 2lh6A-1cynA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3b ATP-DEPENDENT
PHOSPHOENOLPYRUVATE
CARBOXYKINASE

(Thermus
thermophilus) 		PF01293
(PEPCK_ATP) 		4 PHE A 467
PHE A 506
PHE A 390
VAL A 352
 None
 1.21A 2lh6A-1j3bA:
0.0		 2lh6A-1j3bA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kaq NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Bacillus
subtilis) 		PF01467
(CTP_transf_like) 		4 PHE A  70
PHE A  36
PHE A  11
HIS A  18
 None
None
None
DND  A 601 (-4.0A)
 1.11A 2lh6A-1kaqA:
0.0		 2lh6A-1kaqA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khw RNA-DIRECTED RNA
POLYMERASE

(Rabbit
hemorrhagic
disease virus) 		PF00680
(RdRP_1) 		4 PHE A 129
PHE A   5
HIS A 165
VAL A 197
 None
 1.25A 2lh6A-1khwA:
0.0		 2lh6A-1khwA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pdk PROTEIN (PROTEIN
PAPK)

(Escherichia
coli) 		PF00419
(Fimbrial) 		4 PHE B 152
PHE B 125
HIS B 108
VAL B  63
 None
 0.76A 2lh6A-1pdkB:
undetectable		 2lh6A-1pdkB:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4n AMYLOID BETA
PRECURSOR
PROTEIN-BINDING
PROTEIN 1

(Homo sapiens) 		PF00899
(ThiF) 		4 PHE A 120
PHE A 119
HIS A  32
VAL A 126
 None
 1.26A 2lh6A-1r4nA:
0.0		 2lh6A-1r4nA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uc7 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD

(Escherichia
coli) 		PF13899
(Thioredoxin_7) 		4 PHE A  46
PHE A  51
PHE A  10
VAL A 107
 None
 1.24A 2lh6A-1uc7A:
undetectable		 2lh6A-1uc7A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upn ECHOVIRUS 11 COAT
PROTEIN VP3

(Enterovirus B) 		PF00073
(Rhv) 		4 PHE C  95
PHE C  85
PHE C  83
VAL C 214
 None
 1.15A 2lh6A-1upnC:
undetectable		 2lh6A-1upnC:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xq7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trypanosoma
cruzi) 		PF00160
(Pro_isomerase) 		4 PHE A  38
PHE A 113
PHE A  55
VAL A   8
 None
 1.27A 2lh6A-1xq7A:
undetectable		 2lh6A-1xq7A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygg PHOSPHOENOLPYRUVATE
CARBOXYKINASE

(Actinobacillus
succinogenes) 		PF01293
(PEPCK_ATP) 		4 PHE A 478
PHE A 517
PHE A 405
VAL A 367
 None
 1.22A 2lh6A-1yggA:
undetectable		 2lh6A-1yggA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]

(Anaerobiospirillum
succiniciproducens) 		PF01293
(PEPCK_ATP) 		4 PHE A 472
PHE A 511
PHE A 399
VAL A 361
 None
 1.14A 2lh6A-1ytmA:
0.0		 2lh6A-1ytmA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bx6 XRP2 PROTEIN

(Homo sapiens) 		PF07986
(TBCC) 		4 PHE A  75
PHE A  92
PHE A 148
VAL A 212
 None
 1.24A 2lh6A-2bx6A:
0.9		 2lh6A-2bx6A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bzw APOPTOSIS REGULATOR
BCL-X

(Mus musculus) 		PF00452
(Bcl-2)
PF02180
(BH4) 		4 PHE A 144
PHE A 143
PHE A 123
VAL A   9
 None
 1.10A 2lh6A-2bzwA:
undetectable		 2lh6A-2bzwA:
24.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gdm LEGHEMOGLOBIN (OXY)

(Lupinus luteus) 		PF00042
(Globin) 		4 PHE A  29
PHE A  30
PHE A  46
VAL A  67
 None
None
HEM  A 154 ( 4.9A)
HEM  A 154 ( 4.1A)
 0.50A 2lh6A-2gdmA:
24.6		 2lh6A-2gdmA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hgm HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN F

(Homo sapiens) 		PF00076
(RRM_1) 		4 PHE A 130
PHE A 131
PHE A 159
VAL A 183
 None
 1.25A 2lh6A-2hgmA:
undetectable		 2lh6A-2hgmA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iae SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 PHE B 144
PHE B 150
PHE B 193
VAL B  96
 None
 1.14A 2lh6A-2iaeB:
undetectable		 2lh6A-2iaeB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iy0 RAN
GTPASE-ACTIVATING
PROTEIN 1

(Homo sapiens) 		PF07834
(RanGAP1_C) 		4 PHE C 473
PHE C 512
PHE C 507
VAL C 494
 None
 1.26A 2lh6A-2iy0C:
undetectable		 2lh6A-2iy0C:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jak SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 PHE A 144
PHE A 150
PHE A 193
VAL A  96
 None
 1.26A 2lh6A-2jakA:
undetectable		 2lh6A-2jakA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l73 NADPH OXIDASE
ORGANIZER 1

(Homo sapiens) 		PF00787
(PX) 		4 PHE A 119
PHE A 118
PHE A  45
VAL A  10
 None
 1.19A 2lh6A-2l73A:
undetectable		 2lh6A-2l73A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nul PEPTIDYLPROLYL
ISOMERASE

(Escherichia
coli) 		PF00160
(Pro_isomerase) 		4 PHE A  27
PHE A  98
PHE A  41
VAL A   2
 None
 1.26A 2lh6A-2nulA:
undetectable		 2lh6A-2nulA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p2v ALPHA-2,3-SIALYLTRAN
SFERASE

(Campylobacter
jejuni) 		PF06002
(CST-I) 		4 PHE A  65
PHE A  70
PHE A 110
VAL A  63
 None
 1.08A 2lh6A-2p2vA:
undetectable		 2lh6A-2p2vA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhs LIPOYLTRANSFERASE

(Thermus
thermophilus) 		PF03099
(BPL_LplA_LipB) 		4 PHE A   3
PHE A 201
PHE A 153
VAL A   5
 None
 1.17A 2lh6A-2qhsA:
undetectable		 2lh6A-2qhsA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhu LIPOYLTRANSFERASE

(Thermus
thermophilus) 		PF03099
(BPL_LplA_LipB) 		4 PHE A   3
PHE A 201
PHE A 153
VAL A   5
 None
 1.19A 2lh6A-2qhuA:
undetectable		 2lh6A-2qhuA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rmc PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
C

(Mus musculus) 		PF00160
(Pro_isomerase) 		4 PHE A  70
PHE A 146
PHE A  87
VAL A  40
 None
 1.23A 2lh6A-2rmcA:
undetectable		 2lh6A-2rmcA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vtw FIBER PROTEIN 2

(Fowl
aviadenovirus A) 		PF16812
(AdHead_fibreRBD) 		4 PHE A 226
PHE A 234
PHE A 384
VAL A 255
 None
 1.27A 2lh6A-2vtwA:
undetectable		 2lh6A-2vtwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wd6 AGGLUTININ RECEPTOR

(Streptococcus
gordonii) 		PF06696
(Strep_SA_rep)
PF08363
(GbpC) 		4 PHE A 496
PHE A 747
PHE A 733
VAL A 583
 None
 1.26A 2lh6A-2wd6A:
undetectable		 2lh6A-2wd6A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa0 APOPTOSIS REGULATOR
BCL-2

(Homo sapiens) 		PF00452
(Bcl-2)
PF02180
(BH4) 		4 PHE A 151
PHE A 150
PHE A 130
VAL A  15
 None
 1.16A 2lh6A-2xa0A:
undetectable		 2lh6A-2xa0A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xom ARABINOGALACTAN
ENDO-1,4-BETA-GALACT
OSIDASE

(Thermotoga
maritima) 		no annotation 4 PHE A  35
PHE A  30
PHE A 160
VAL A  40
 None
 0.93A 2lh6A-2xomA:
undetectable		 2lh6A-2xomA:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsw 72 KDA INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		4 PHE A 473
PHE A 420
PHE A 411
VAL A 593
 None
 1.08A 2lh6A-2xswA:
undetectable		 2lh6A-2xswA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9y IMITATION SWITCH
PROTEIN 1
(DEL_ATPASE)
ISWI ONE COMPLEX
PROTEIN 3

(Saccharomyces
cerevisiae) 		PF09110
(HAND)
PF09111
(SLIDE)
PF15612
(WHIM1) 		4 PHE A 975
PHE A 976
HIS B 613
VAL B 615
 None
 1.02A 2lh6A-2y9yA:
undetectable		 2lh6A-2y9yA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ya1 PUTATIVE ALKALINE
AMYLOPULLULANASE

(Streptococcus
pneumoniae) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48)
PF03714
(PUD) 		4 PHE A 303
PHE A 326
HIS A 332
VAL A 246
 None
 1.19A 2lh6A-2ya1A:
undetectable		 2lh6A-2ya1A:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yro GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  99
PHE A  93
PHE A  71
VAL A  35
 None
 0.95A 2lh6A-2yroA:
undetectable		 2lh6A-2yroA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afo NADH KINASE POS5

(Saccharomyces
cerevisiae) 		PF01513
(NAD_kinase) 		4 PHE A 182
PHE A 171
PHE A  88
VAL A 383
 None
 1.20A 2lh6A-3afoA:
undetectable		 2lh6A-3afoA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiv BETA-GLUCOSIDASE

(Secale cereale) 		PF00232
(Glyco_hydro_1) 		4 PHE A  33
PHE A  35
PHE A 496
VAL A 439
 None
 1.27A 2lh6A-3aivA:
0.9		 2lh6A-3aivA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC

(Bordetella
parapertussis) 		no annotation 4 PHE A  37
PHE A  87
PHE A 150
VAL A 124
 None
 1.13A 2lh6A-3d0kA:
undetectable		 2lh6A-3d0kA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dsh INTERFERON
REGULATORY FACTOR 5

(Homo sapiens) 		PF10401
(IRF-3) 		4 PHE A 387
PHE A 389
PHE A 289
VAL A 408
 None
 1.23A 2lh6A-3dshA:
undetectable		 2lh6A-3dshA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fds DNA POLYMERASE
SLIDING CLAMP C

(Sulfolobus
solfataricus) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 PHE D  60
PHE D  57
PHE D  12
VAL D  30
 None
 1.26A 2lh6A-3fdsD:
undetectable		 2lh6A-3fdsD:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7u CYTOSINE-SPECIFIC
METHYLTRANSFERASE

(Escherichia
coli) 		PF00145
(DNA_methylase) 		4 PHE A 334
PHE A 332
PHE A  42
HIS A  38
 None
 1.01A 2lh6A-3g7uA:
undetectable		 2lh6A-3g7uA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2y GTPASE FAMILY
PROTEIN

(Bacillus
anthracis) 		PF01926
(MMR_HSR1) 		4 PHE A 336
PHE A 280
HIS A 279
VAL A 334
 None
 1.24A 2lh6A-3h2yA:
undetectable		 2lh6A-3h2yA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hq0 CATECHOL
2,3-DIOXYGENASE

(Pseudomonas
alkylphenolica) 		PF00903
(Glyoxalase) 		4 PHE A 175
PHE A 169
PHE A 110
VAL A   6
 None
 1.27A 2lh6A-3hq0A:
undetectable		 2lh6A-3hq0A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ilr HEPARIN LYASE I

(Bacteroides
thetaiotaomicron) 		PF14099
(Polysacc_lyase) 		4 PHE A 147
PHE A 233
PHE A 284
VAL A 133
 None
 1.22A 2lh6A-3ilrA:
undetectable		 2lh6A-3ilrA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nr8 PHOSPHATIDYLINOSITOL
-3,4,5-TRISPHOSPHATE
5-PHOSPHATASE 2

(Homo sapiens) 		no annotation 4 PHE B 603
PHE B 557
PHE B 548
VAL B 727
 None
 1.07A 2lh6A-3nr8B:
undetectable		 2lh6A-3nr8B:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)

(Corynebacterium
glutamicum) 		PF01370
(Epimerase)
PF08338
(DUF1731) 		4 PHE A  75
PHE A  96
HIS A  20
VAL A  26
 None
 1.12A 2lh6A-3oh8A:
undetectable		 2lh6A-3oh8A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojb GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  91
PHE A  85
PHE A  63
VAL A  27
 None
 0.88A 2lh6A-3ojbA:
undetectable		 2lh6A-3ojbA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q08 CHLORITE DISMUTASE

(Dechloromonas
aromatica) 		PF06778
(Chlor_dismutase) 		4 PHE A  75
PHE A  77
PHE A  90
VAL A  99
 None
 1.19A 2lh6A-3q08A:
undetectable		 2lh6A-3q08A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qqr NON-LEGUME
HEMOGLOBIN

(Parasponia
andersonii) 		PF00042
(Globin) 		4 PHE A  36
PHE A  37
PHE A  51
VAL A  74
 None
None
HEM  A 163 (-3.8A)
HEM  A 163 ( 4.4A)
 0.82A 2lh6A-3qqrA:
19.6		 2lh6A-3qqrA:
41.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Mycobacteroides
abscessus) 		PF01259
(SAICAR_synt) 		4 PHE A 201
PHE A 199
PHE A 216
VAL A  66
 PHE  A 201 ( 1.3A)
PHE  A 199 ( 1.3A)
PHE  A 216 ( 1.3A)
VAL  A  66 ( 0.6A)
 1.16A 2lh6A-3r9rA:
undetectable		 2lh6A-3r9rA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg0 CALRETICULIN

(Mus musculus) 		PF00262
(Calreticulin) 		4 PHE A  95
PHE A 330
PHE A  27
VAL A  97
 None
 1.12A 2lh6A-3rg0A:
undetectable		 2lh6A-3rg0A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6m PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Burkholderia
pseudomallei) 		PF00160
(Pro_isomerase) 		4 PHE A  27
PHE A  98
PHE A  41
VAL A   2
 None
 1.22A 2lh6A-3s6mA:
undetectable		 2lh6A-3s6mA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Azotobacter
vinelandii) 		PF00160
(Pro_isomerase) 		4 PHE A  27
PHE A  98
PHE A  41
VAL A  31
 None
 1.21A 2lh6A-3t1uA:
undetectable		 2lh6A-3t1uA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty7 PUTATIVE ALDEHYDE
DEHYDROGENASE
SAV2122

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		4 PHE A 196
PHE A 186
PHE A 111
VAL A 167
 None
 1.15A 2lh6A-3ty7A:
2.0		 2lh6A-3ty7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uaq LBPB B-LOBE

(Moraxella bovis) 		PF01298
(TbpB_B_D)
PF17484
(TbpB_A) 		4 PHE A 301
PHE A 179
HIS A 236
VAL A 268
 None
 1.09A 2lh6A-3uaqA:
undetectable		 2lh6A-3uaqA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vns NRPS ADENYLATION
PROTEIN CYTC1

(Streptomyces
sp.) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 PHE A 318
PHE A 315
PHE A 209
VAL A 304
 None
DVA  A 602 (-3.7A)
DVA  A 602 ( 4.2A)
None
 1.22A 2lh6A-3vnsA:
undetectable		 2lh6A-3vnsA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 PHE A 719
PHE A 743
PHE A 771
VAL A 714
 None
 0.91A 2lh6A-3wpeA:
undetectable		 2lh6A-3wpeA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE

(Vibrio
parahaemolyticus) 		PF01522
(Polysacc_deac_1) 		4 PHE A 249
PHE A 314
PHE A 325
VAL A 227
 None
 1.26A 2lh6A-3wx7A:
undetectable		 2lh6A-3wx7A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4doi CHALCONE--FLAVONONE
ISOMERASE 1

(Arabidopsis
thaliana) 		PF02431
(Chalcone) 		4 PHE A 146
PHE A 150
PHE A 155
VAL A 121
 None
 1.24A 2lh6A-4doiA:
undetectable		 2lh6A-4doiA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqz GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A 267
PHE A 261
PHE A 239
VAL A 203
 None
 0.88A 2lh6A-4fqzA:
undetectable		 2lh6A-4fqzA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9d GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Brugia malayi) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 PHE A  56
PHE A  47
PHE A  11
VAL A  23
 None
 1.07A 2lh6A-4k9dA:
undetectable		 2lh6A-4k9dA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kh8 HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF16103
(DUF4822) 		4 PHE A 257
PHE A 266
HIS A 292
VAL A 283
 None
 1.09A 2lh6A-4kh8A:
undetectable		 2lh6A-4kh8A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius) 		no annotation 4 PHE A 167
PHE A 131
PHE A 122
VAL A 280
 None
 1.16A 2lh6A-4l1yA:
undetectable		 2lh6A-4l1yA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC

(Shewanella
oneidensis) 		PF14522
(Cytochrome_C7) 		4 PHE A 126
PHE A 129
PHE A 135
VAL A  65
 None
 1.10A 2lh6A-4lm8A:
undetectable		 2lh6A-4lm8A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lry PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
DIHYDROXYACETONE-BIN
DING SUBUNIT DHAK

(Escherichia
coli) 		PF02733
(Dak1) 		4 PHE A 204
PHE A  78
HIS A 218
VAL A 215
 None
None
GOL  A 401 (-3.2A)
None
 1.01A 2lh6A-4lryA:
undetectable		 2lh6A-4lryA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0f IGG RECEPTOR FCRN
LARGE SUBUNIT P51

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 PHE A  24
PHE A  75
PHE A 110
VAL A  26
 None
 1.07A 2lh6A-4n0fA:
undetectable		 2lh6A-4n0fA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nw4 LIPOPROTEIN S-LAYER
PROTEIN

(Enterococcus
faecalis) 		PF16103
(DUF4822) 		4 PHE A 231
PHE A 240
HIS A 266
VAL A 257
 None
SO4  A 403 (-3.6A)
None
GOL  A 407 (-4.1A)
 1.11A 2lh6A-4nw4A:
undetectable		 2lh6A-4nw4A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oxr MANGANESE ABC
TRANSPORTER,
PERIPLASMIC-BINDING
PROTEIN SITA

(Staphylococcus
pseudintermedius) 		PF01297
(ZnuA) 		4 PHE A 206
PHE A 209
PHE A 189
VAL A 275
 None
 1.23A 2lh6A-4oxrA:
2.1		 2lh6A-4oxrA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qnq BCL-2-LIKE PROTEIN 1

(Rattus
norvegicus) 		PF00452
(Bcl-2)
PF02180
(BH4) 		4 PHE A 144
PHE A 143
PHE A 123
VAL A   9
 None
 1.14A 2lh6A-4qnqA:
undetectable		 2lh6A-4qnqA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 PHE A1591
PHE A1595
PHE A1503
VAL A1552
 None
 1.18A 2lh6A-4r04A:
undetectable		 2lh6A-4r04A:
6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4k UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		no annotation 4 PHE A  46
PHE A  43
PHE A 114
VAL A 149
 None
ACT  A 202 ( 4.9A)
ACT  A 202 ( 4.4A)
None
 1.23A 2lh6A-4r4kA:
undetectable		 2lh6A-4r4kA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE

(Clitoria
ternatea) 		PF00201
(UDPGT) 		4 PHE A 395
PHE A 390
PHE A 364
VAL A 269
 None
 1.24A 2lh6A-4whmA:
undetectable		 2lh6A-4whmA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x0e PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		4 PHE A  71
PHE A  38
PHE A  13
HIS A  20
 None
 1.04A 2lh6A-4x0eA:
undetectable		 2lh6A-4x0eA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhf NA-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C
NQRC

(Shewanella
oneidensis) 		PF04205
(FMN_bind) 		4 PHE A 247
PHE A 248
PHE A 239
VAL A 123
 None
 1.16A 2lh6A-4xhfA:
undetectable		 2lh6A-4xhfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9v PARTICLE-ASSOCIATED
LYASE

(Acinetobacter
virus AP22) 		no annotation 4 PHE A 198
PHE A 200
PHE A 208
VAL A 171
 None
 1.02A 2lh6A-4y9vA:
undetectable		 2lh6A-4y9vA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		4 PHE A  71
PHE A  38
PHE A  13
HIS A  20
 None
None
NAP  A 301 ( 4.9A)
NAP  A 301 (-3.8A)
 1.07A 2lh6A-4ybrA:
undetectable		 2lh6A-4ybrA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgi TRAF-INTERACTING
PROTEIN WITH FHA
DOMAIN-CONTAINING
PROTEIN A

(Homo sapiens) 		PF00498
(FHA) 		4 PHE A 119
PHE A 124
PHE A 141
VAL A  65
 None
 1.27A 2lh6A-4zgiA:
undetectable		 2lh6A-4zgiA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a53 RIBOSOME BIOGENESIS
PROTEIN RPF2

(Saccharomyces
cerevisiae) 		PF04427
(Brix) 		4 PHE C 164
PHE C 165
PHE C 201
VAL C  88
 None
 1.20A 2lh6A-5a53C:
undetectable		 2lh6A-5a53C:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c98 AGAP007691-PB

(Anopheles
gambiae) 		PF00079
(Serpin) 		4 PHE A 365
PHE A 363
PHE A 204
VAL A 292
 None
 1.21A 2lh6A-5c98A:
undetectable		 2lh6A-5c98A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5db4 NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF01467
(CTP_transf_like) 		4 PHE A  74
PHE A  40
PHE A  15
HIS A  22
 None
None
None
ATP  A 301 (-4.0A)
 1.08A 2lh6A-5db4A:
undetectable		 2lh6A-5db4A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ex1 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN TYPE

(Hirschia
baltica) 		PF00160
(Pro_isomerase) 		4 PHE A  63
PHE A 166
PHE A  77
VAL A  38
 None
 1.24A 2lh6A-5ex1A:
undetectable		 2lh6A-5ex1A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5has SEC7

(Thielavia
terrestris) 		PF12783
(Sec7_N)
PF16213
(DCB) 		4 PHE A 376
PHE A 358
HIS A 354
VAL A 180
 None
 1.25A 2lh6A-5hasA:
undetectable		 2lh6A-5hasA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpk E3 UBIQUITIN-PROTEIN
LIGASE NEDD4-LIKE

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A 893
PHE A 905
PHE A 863
VAL A 838
 None
 1.20A 2lh6A-5hpkA:
undetectable		 2lh6A-5hpkA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jja SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 PHE A 144
PHE A 150
PHE A 193
VAL A  96
 PHE  A 144 ( 1.3A)
PHE  A 150 ( 1.3A)
PHE  A 193 ( 1.3A)
VAL  A  96 ( 0.6A)
 1.16A 2lh6A-5jjaA:
undetectable		 2lh6A-5jjaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kx6 GALACTOSIDE
2-ALPHA-L-FUCOSYLTRA
NSFERASE

(Arabidopsis
thaliana) 		PF03254
(XG_FTase) 		4 PHE A 280
PHE A 281
PHE A 522
VAL A 297
 None
 1.09A 2lh6A-5kx6A:
undetectable		 2lh6A-5kx6A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nrm ENDOGLUCANASE

(Acetivibrio
cellulolyticus) 		no annotation 4 PHE A  38
PHE A 122
PHE A   4
VAL A  23
 None
 1.21A 2lh6A-5nrmA:
undetectable		 2lh6A-5nrmA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oko PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE
5-PHOSPHATASE 2

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		4 PHE A 603
PHE A 557
PHE A 548
VAL A 727
 None
 1.13A 2lh6A-5okoA:
undetectable		 2lh6A-5okoA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqp CONDENSIN COMPLEX
SUBUNIT 3

(Saccharomyces
cerevisiae) 		no annotation 4 PHE A 118
PHE A 114
PHE A  54
VAL A  62
 None
 1.09A 2lh6A-5oqpA:
undetectable		 2lh6A-5oqpA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4o ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Bacillus
anthracis) 		PF00496
(SBP_bac_5) 		4 PHE A 434
PHE A 446
PHE A 415
VAL A 328
 None
 1.20A 2lh6A-5u4oA:
undetectable		 2lh6A-5u4oA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve9 MICROTUBULE-ACTIN
CROSS-LINKING FACTOR
1, ISOFORMS 1/2/3/5

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 PHE A7102
PHE A7089
PHE A7028
VAL A7046
 None
 1.27A 2lh6A-5ve9A:
undetectable		 2lh6A-5ve9A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vkp POTASSIUM CHANNEL
SUBFAMILY K MEMBER 2

(Mus musculus) 		PF07885
(Ion_trans_2) 		4 PHE A 230
PHE A 244
PHE A 145
VAL A 274
 None
None
None
Q5F  A 404 (-3.7A)
 1.25A 2lh6A-5vkpA:
1.0		 2lh6A-5vkpA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vxb PROXP-ALA

(Caulobacter
vibrioides) 		PF04073
(tRNA_edit) 		4 PHE A 129
PHE A 103
PHE A  11
VAL A 127
 None
 1.04A 2lh6A-5vxbA:
undetectable		 2lh6A-5vxbA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus) 		no annotation 4 PHE A 563
PHE A 577
HIS A 537
VAL A 533
 None
 1.20A 2lh6A-5w1jA:
undetectable		 2lh6A-5w1jA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 PHE A 721
PHE A 745
PHE A 773
VAL A 716
 None
 1.11A 2lh6A-5y3jA:
undetectable		 2lh6A-5y3jA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y82 MEMBRANE PROTEIN
INSERTASE YIDC

(Thermotoga
maritima) 		no annotation 4 PHE D  72
PHE D 178
HIS D 172
VAL D 192
 None
 1.14A 2lh6A-5y82D:
undetectable		 2lh6A-5y82D:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y83 MEMBRANE PROTEIN
INSERTASE YIDC

(Thermotoga
maritima) 		no annotation 4 PHE A  72
PHE A 178
HIS A 172
VAL A 192
 None
 1.13A 2lh6A-5y83A:
undetectable		 2lh6A-5y83A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zh6 -

(-) 		no annotation 4 PHE A  68
PHE A  64
PHE A  83
VAL A  44
 None
 1.15A 2lh6A-5zh6A:
undetectable		 2lh6A-5zh6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d5i PHOSPHOENOLPYRUVATE
CARBOXYKINASE (ATP)

(Escherichia
coli) 		no annotation 4 PHE A 478
PHE A 517
PHE A 405
VAL A 367
 None
 1.23A 2lh6A-6d5iA:
undetectable		 2lh6A-6d5iA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ekt P-47 PROTEIN

(Clostridium
botulinum) 		no annotation 4 PHE A 247
PHE A 430
PHE A 403
VAL A 252
 None
 1.17A 2lh6A-6ektA:
undetectable		 2lh6A-6ektA:
16.86