SIMILAR PATTERNS OF AMINO ACIDS FOR 2JKJ_F_CLMF1143_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a87 COLICIN N

(Escherichia
coli)
PF01024
(Colicin)
4 PRO A 101
PRO A 106
GLY A 107
TYR A 109
None
0.83A 2jkjF-1a87A:
undetectable
2jkjF-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b6r PROTEIN
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
SYNTHETASE)


(Escherichia
coli)
PF02222
(ATP-grasp)
4 PRO A 241
ILE A 266
GLY A 221
TYR A 219
None
1.13A 2jkjF-1b6rA:
0.0
2jkjF-1b6rA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dcu FRUCTOSE-1,6-BISPHOS
PHATASE


(Pisum sativum)
PF00316
(FBPase)
4 PRO A 180
ILE A 143
GLY A 145
TYR A 147
None
1.06A 2jkjF-1dcuA:
0.0
2jkjF-1dcuA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee8 MUTM (FPG) PROTEIN

(Thermus
thermophilus)
PF01149
(Fapy_DNA_glyco)
PF06827
(zf-FPG_IleRS)
PF06831
(H2TH)
4 PRO A   1
PRO A   4
GLY A 206
TYR A 214
None
1.17A 2jkjF-1ee8A:
0.0
2jkjF-1ee8A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m5y SURVIVAL PROTEIN
SURA


(Escherichia
coli)
PF00639
(Rotamase)
PF09312
(SurA_N)
PF13616
(Rotamase_3)
4 PRO A 184
PRO A 182
ILE A 181
GLY A 264
None
0.92A 2jkjF-1m5yA:
0.0
2jkjF-1m5yA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1na6 RESTRICTION
ENDONUCLEASE ECORII


(Escherichia
coli)
PF09019
(EcoRII-C)
PF09217
(EcoRII-N)
4 PRO A 371
PRO A 214
ILE A 393
GLY A 390
None
1.07A 2jkjF-1na6A:
0.0
2jkjF-1na6A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvt SHIKIMATE
5'-DEHYDROGENASE


(Methanocaldococcus
jannaschii)
PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N)
4 PRO A  27
ILE A  17
GLY A  15
TYR A  43
None
1.10A 2jkjF-1nvtA:
0.0
2jkjF-1nvtA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ow0 IMMUNOGLOBULIN ALPHA
FC RECEPTOR


(Homo sapiens)
no annotation 4 PRO C 180
ILE C  42
GLY C  75
TYR C 181
None
1.08A 2jkjF-1ow0C:
0.0
2jkjF-1ow0C:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pby QUINOHEMOPROTEIN
AMINE DEHYDROGENASE
60 KDA SUBUNIT


(Paracoccus
denitrificans)
PF09098
(Dehyd-heme_bind)
PF09099
(Qn_am_d_aIII)
PF09100
(Qn_am_d_aIV)
PF14930
(Qn_am_d_aII)
4 PRO A 378
PRO A 375
ILE A 374
GLY A 368
None
1.15A 2jkjF-1pbyA:
0.0
2jkjF-1pbyA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)


(Ascophyllum
nodosum)
no annotation 4 PRO A  98
PRO A 252
ILE A 246
GLY A 250
None
1.05A 2jkjF-1qi9A:
undetectable
2jkjF-1qi9A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3)
PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N)
4 PRO B 110
PRO B 239
ILE B 260
GLY B 242
None
0.99A 2jkjF-1skyB:
undetectable
2jkjF-1skyB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE


(Arabidopsis
thaliana)
PF00903
(Glyoxalase)
4 PRO A 318
ILE A 359
GLY A 345
TYR A 322
None
1.13A 2jkjF-1tg5A:
undetectable
2jkjF-1tg5A:
15.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT


(Escherichia
coli)
PF04619
(Adhesin_Dr)
5 PRO A  40
PRO A  43
ILE A 111
GLY A 113
TYR A 115
EDO  A1143 ( 4.3A)
None
None
None
None
0.54A 2jkjF-1ut1A:
27.4
2jkjF-1ut1A:
99.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5f PYRUVATE OXIDASE

(Aerococcus
viridans)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 PRO A 189
PRO A 192
ILE A 317
GLY A 319
None
1.06A 2jkjF-1v5fA:
undetectable
2jkjF-1v5fA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wjm BETA-SPECTRIN III

(Homo sapiens)
PF15410
(PH_9)
4 PRO A  58
PRO A  64
GLY A  45
TYR A  47
None
1.08A 2jkjF-1wjmA:
undetectable
2jkjF-1wjmA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xsz GUANINE NUCLEOTIDE
EXCHANGE PROTEIN


(Legionella
pneumophila)
PF01369
(Sec7)
4 PRO A 201
PRO A 101
ILE A 107
GLY A 102
None
1.09A 2jkjF-1xszA:
undetectable
2jkjF-1xszA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ywk 4-DEOXY-L-THREO-5-HE
XOSULOSE-URONATE
KETOL-ISOMERASE 1


(Enterococcus
faecalis)
PF04962
(KduI)
4 PRO A1009
PRO A1221
ILE A1242
GLY A1219
None
1.16A 2jkjF-1ywkA:
1.2
2jkjF-1ywkA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z5v TUBULIN GAMMA-1
CHAIN


(Homo sapiens)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
4 PRO A 365
ILE A  36
GLY A  30
TYR A 366
None
1.11A 2jkjF-1z5vA:
undetectable
2jkjF-1z5vA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zr9 ZINC FINGER PROTEIN
593


(Homo sapiens)
PF12171
(zf-C2H2_jaz)
4 PRO A  35
PRO A  38
ILE A  53
GLY A  39
None
1.15A 2jkjF-1zr9A:
undetectable
2jkjF-1zr9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bru NAD(P)
TRANSHYDROGENASE
SUBUNIT ALPHA


(Escherichia
coli)
PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N)
4 PRO A1095
PRO A1259
ILE A1258
GLY A1260
None
1.03A 2jkjF-2bruA:
undetectable
2jkjF-2bruA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2czt PROSTAGLANDIN-H2
D-ISOMERASE


(Mus musculus)
PF00061
(Lipocalin)
4 PRO A  98
PRO A 102
GLY A 103
TYR A 105
None
0.58A 2jkjF-2cztA:
undetectable
2jkjF-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egg SHIKIMATE
5-DEHYDROGENASE


(Geobacillus
kaustophilus)
PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N)
4 PRO A  39
ILE A  29
GLY A  27
TYR A  55
None
1.18A 2jkjF-2eggA:
undetectable
2jkjF-2eggA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR


(Escherichia
coli)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF)
4 PRO A 522
ILE A 504
GLY A 506
TYR A 508
None
0.70A 2jkjF-2eyqA:
undetectable
2jkjF-2eyqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsb RAS
GTPASE-ACTIVATING
PROTEIN 1


(Homo sapiens)
PF00017
(SH2)
4 PRO A  45
PRO A  50
GLY A  51
TYR A  53
None
1.06A 2jkjF-2gsbA:
undetectable
2jkjF-2gsbA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i76 HYPOTHETICAL PROTEIN

(Thermotoga
maritima)
PF10728
(DUF2520)
4 PRO A 105
ILE A 103
GLY A 125
TYR A 158
NDP  A 301 (-4.0A)
None
None
None
1.06A 2jkjF-2i76A:
undetectable
2jkjF-2i76A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mau WRIGHTIDE R1

(Wrightia
religiosa)
no annotation 4 PRO A  23
ILE A  25
GLY A  27
TYR A   7
None
1.16A 2jkjF-2mauA:
undetectable
2jkjF-2mauA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2my9 RETINOIC ACID
RECEPTOR RESPONDER
PROTEIN 3


(Homo sapiens)
PF04970
(LRAT)
4 PRO A   8
PRO A  10
ILE A  93
GLY A  11
None
0.95A 2jkjF-2my9A:
undetectable
2jkjF-2my9A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pp3 L-TALARATE/GALACTARA
TE DEHYDRATASE


(Salmonella
enterica)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 PRO A 300
PRO A 303
ILE A 137
GLY A 307
None
1.12A 2jkjF-2pp3A:
undetectable
2jkjF-2pp3A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pv2 CHAPERONE SURA

(Escherichia
coli)
PF00639
(Rotamase)
4 PRO A 184
PRO A 182
ILE A 181
GLY A 264
None
0.98A 2jkjF-2pv2A:
undetectable
2jkjF-2pv2A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1d 2-KETO-3-DEOXY-D-ARA
BINONATE DEHYDRATASE


(Sulfolobus
solfataricus)
PF01557
(FAA_hydrolase)
4 PRO X  30
PRO X  73
ILE X 251
GLY X 249
None
1.03A 2jkjF-2q1dX:
undetectable
2jkjF-2q1dX:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uu7 GLUTAMINE SYNTHETASE

(Canis lupus)
PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N)
4 PRO A 199
PRO A 146
GLY A 148
TYR A 171
None
1.17A 2jkjF-2uu7A:
undetectable
2jkjF-2uu7A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v84 SPERMIDINE/PUTRESCIN
E ABC TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN


(Treponema
pallidum)
PF13416
(SBP_bac_8)
4 PRO A 236
PRO A 230
ILE A 116
GLY A 115
None
1.06A 2jkjF-2v84A:
undetectable
2jkjF-2v84A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbp L-ARGININE
BETA-HYDROXYLASE


(Streptomyces
vinaceus)
PF02668
(TauD)
4 PRO A 263
PRO A 200
ILE A 292
GLY A 198
None
1.05A 2jkjF-2wbpA:
undetectable
2jkjF-2wbpA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE


(Candida
albicans)
PF00133
(tRNA-synt_1)
4 PRO A 332
ILE A 381
GLY A 377
TYR A 336
None
1.08A 2jkjF-2wfgA:
undetectable
2jkjF-2wfgA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wk2 CHITINASE A

(Serratia
marcescens)
PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N)
4 PRO A 280
PRO A 193
ILE A 192
GLY A 273
None
1.15A 2jkjF-2wk2A:
undetectable
2jkjF-2wk2A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA


(Homo sapiens)
PF04321
(RmlD_sub_bind)
5 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
None
1.49A 2jkjF-2ydyA:
undetectable
2jkjF-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoo PROBABLE NITRITE
REDUCTASE


(Pseudoalteromonas
haloplanktis)
PF00034
(Cytochrom_C)
PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3)
4 PRO A 367
PRO A 362
GLY A 363
TYR A 400
HEM  A 600 (-4.5A)
SUC  A 700 (-4.4A)
SUC  A 700 ( 3.8A)
None
1.10A 2jkjF-2zooA:
undetectable
2jkjF-2zooA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5r BENZALACETONE
SYNTHASE


(Rheum palmatum)
PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C)
4 PRO A 265
PRO A 300
ILE A 207
GLY A 298
None
None
HC4  A 400 ( 4.5A)
None
1.14A 2jkjF-3a5rA:
undetectable
2jkjF-3a5rA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9e CHITINASE A

(Vibrio harveyi)
PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N)
4 PRO A 280
PRO A 194
ILE A 193
GLY A 273
None
1.05A 2jkjF-3b9eA:
undetectable
2jkjF-3b9eA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdk SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE SUBUNIT
A


(Bacillus
subtilis)
PF01144
(CoA_trans)
4 PRO A 208
PRO A 178
ILE A 179
TYR A 211
None
0.98A 2jkjF-3cdkA:
undetectable
2jkjF-3cdkA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgw LPPG:FO
2-PHOSPHO-L-LACTATE
TRANSFERASE


(Methanosarcina
mazei)
PF01933
(UPF0052)
4 PRO A 194
PRO A 200
ILE A 165
TYR A 251
None
1.16A 2jkjF-3cgwA:
undetectable
2jkjF-3cgwA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3es4 UNCHARACTERIZED
PROTEIN DUF861 WITH
A RMLC-LIKE CUPIN
FOLD


(Agrobacterium
fabrum)
PF05899
(Cupin_3)
4 PRO A  16
PRO A  19
GLY A  26
TYR A  28
None
0.96A 2jkjF-3es4A:
undetectable
2jkjF-3es4A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6u VITAMIN K-DEPENDENT
PROTEIN C HEAVY
CHAIN


(Homo sapiens)
PF00089
(Trypsin)
4 PRO H 164
PRO H 161
ILE H 184
GLY H 184
None
1.13A 2jkjF-3f6uH:
undetectable
2jkjF-3f6uH:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE


(Bordetella
bronchiseptica)
PF14497
(GST_C_3)
4 PRO A  56
ILE A 223
GLY A  13
TYR A   7
None
CL  A 234 (-4.2A)
CL  A 234 (-3.6A)
None
1.09A 2jkjF-3h1nA:
undetectable
2jkjF-3h1nA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hx3 RETINALDEHYDE-BINDIN
G PROTEIN 1


(Homo sapiens)
PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N)
4 PRO A 145
ILE A 140
GLY A 143
TYR A 296
None
1.01A 2jkjF-3hx3A:
undetectable
2jkjF-3hx3A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jyo QUINATE/SHIKIMATE
DEHYDROGENASE


(Corynebacterium
glutamicum)
PF08501
(Shikimate_dh_N)
4 PRO A  20
ILE A  10
GLY A   8
TYR A  36
None
1.16A 2jkjF-3jyoA:
undetectable
2jkjF-3jyoA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kes NUCLEOPORIN NUP145

(Saccharomyces
cerevisiae)
PF04096
(Nucleoporin2)
4 PRO A 555
PRO A 593
GLY A 596
TYR A 554
None
EDO  A   7 ( 4.4A)
None
None
1.08A 2jkjF-3kesA:
undetectable
2jkjF-3kesA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyd SUMO-ACTIVATING
ENZYME SUBUNIT 1
SUMO-ACTIVATING
ENZYME SUBUNIT 2


(Homo sapiens;
Homo sapiens)
PF00899
(ThiF)
PF00899
(ThiF)
PF14732
(UAE_UbL)
4 PRO B  85
PRO A  76
GLY A  77
TYR B  84
None
1.10A 2jkjF-3kydB:
undetectable
2jkjF-3kydB:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN


(Rhodobacter
capsulatus)
PF00590
(TP_methylase)
4 PRO A 212
PRO A  14
ILE A  50
GLY A  12
None
0.89A 2jkjF-3nd1A:
undetectable
2jkjF-3nd1A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps5 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 6


(Homo sapiens)
PF00017
(SH2)
PF00102
(Y_phosphatase)
4 PRO A 268
PRO A 297
ILE A 296
GLY A 298
None
1.15A 2jkjF-3ps5A:
undetectable
2jkjF-3ps5A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tnl SHIKIMATE
DEHYDROGENASE


(Listeria
monocytogenes)
PF08501
(Shikimate_dh_N)
4 PRO A  29
ILE A  19
GLY A  17
TYR A  45
None
1.12A 2jkjF-3tnlA:
undetectable
2jkjF-3tnlA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsc PUTATIVE
OXIDOREDUCTASE


(Mycobacterium
avium)
PF13561
(adh_short_C2)
4 PRO A  48
PRO A  44
ILE A 127
TYR A  49
None
None
NAD  A 274 (-3.8A)
NAD  A 274 ( 4.8A)
1.05A 2jkjF-3tscA:
undetectable
2jkjF-3tscA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v67 SENSOR PROTEIN CPXA

(Vibrio
parahaemolyticus)
PF16527
(CpxA_peri)
4 PRO A 144
PRO A 129
ILE A  47
GLY A 141
None
1.17A 2jkjF-3v67A:
undetectable
2jkjF-3v67A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vnn DNA LIGASE 4

(Homo sapiens)
PF01068
(DNA_ligase_A_M)
4 PRO A 397
ILE A 396
GLY A 398
TYR A 335
None
1.09A 2jkjF-3vnnA:
undetectable
2jkjF-3vnnA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3r ENOLASE

(Bacillus
subtilis)
PF00113
(Enolase_C)
PF03952
(Enolase_N)
4 PRO A 173
ILE A 422
GLY A 421
TYR A 419
None
1.17A 2jkjF-4a3rA:
undetectable
2jkjF-4a3rA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aie GLUCAN
1,6-ALPHA-GLUCOSIDAS
E


(Lactobacillus
acidophilus)
PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C)
4 PRO A 220
PRO A 216
GLY A 204
TYR A 221
None
1.07A 2jkjF-4aieA:
undetectable
2jkjF-4aieA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ap3 STEROID
MONOOXYGENASE


(Rhodococcus
rhodochrous)
PF00743
(FMO-like)
4 PRO A  99
PRO A  66
ILE A 209
GLY A  67
None
1.11A 2jkjF-4ap3A:
undetectable
2jkjF-4ap3A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7p RALF

(Legionella
pneumophila)
PF01369
(Sec7)
4 PRO A 201
PRO A 101
ILE A 107
GLY A 102
None
1.04A 2jkjF-4c7pA:
undetectable
2jkjF-4c7pA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cg1 CUTINASE

(Thermobifida
fusca)
PF12740
(Chlorophyllase2)
4 PRO A 180
PRO A 154
ILE A 170
GLY A 172
None
1.10A 2jkjF-4cg1A:
undetectable
2jkjF-4cg1A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d4g APNAA1

(Planktothrix
agardhii)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 PRO A  86
PRO A  83
ILE A 153
TYR A  88
None
1.15A 2jkjF-4d4gA:
undetectable
2jkjF-4d4gA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7q RALF,
PROLINE/BETAINE
TRANSPORTER


(Legionella
pneumophila;
Rickettsia
prowazekii)
PF01369
(Sec7)
4 PRO A 201
PRO A 101
ILE A 107
GLY A 102
NO3  A1348 ( 4.6A)
None
None
None
1.02A 2jkjF-4d7qA:
undetectable
2jkjF-4d7qA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7r PROLINE/BETAINE
TRANSPORTER, RALF


(Legionella
pneumophila;
Rickettsia
prowazekii)
PF01369
(Sec7)
4 PRO A 199
PRO A  98
ILE A 104
GLY A  99
None
1.08A 2jkjF-4d7rA:
undetectable
2jkjF-4d7rA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4j ARGININE DEIMINASE

(Mycoplasma
penetrans)
PF02274
(Amidinotransf)
4 PRO A 197
PRO A  72
ILE A  99
GLY A  73
None
1.10A 2jkjF-4e4jA:
undetectable
2jkjF-4e4jA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eb0 LCC

(uncultured
bacterium)
PF12695
(Abhydrolase_5)
4 PRO A 214
PRO A 189
ILE A 204
GLY A 206
None
1.12A 2jkjF-4eb0A:
undetectable
2jkjF-4eb0A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fa0 GROUP XVI
PHOSPHOLIPASE A1/A2


(Homo sapiens)
PF04970
(LRAT)
4 PRO A   8
PRO A  10
ILE A  93
GLY A  11
None
1.12A 2jkjF-4fa0A:
undetectable
2jkjF-4fa0A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga4 PUTATIVE THYMIDINE
PHOSPHORYLASE


(Thermococcus
kodakarensis)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
4 PRO A 323
ILE A 428
GLY A 321
TYR A 319
None
0.96A 2jkjF-4ga4A:
undetectable
2jkjF-4ga4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga6 PUTATIVE THYMIDINE
PHOSPHORYLASE


(Thermococcus
kodakarensis)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
4 PRO A 323
ILE A 428
GLY A 321
TYR A 319
None
1.02A 2jkjF-4ga6A:
undetectable
2jkjF-4ga6A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jvw IG MU CHAIN C REGION
SECRETED FORM


(Mus musculus)
PF07654
(C1-set)
4 PRO A 507
PRO A 512
GLY A 513
TYR A 515
None
0.99A 2jkjF-4jvwA:
undetectable
2jkjF-4jvwA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lp7 MATRIX PROTEIN M

(Human
metapneumovirus)
PF03393
(Pneumo_matrix)
4 PRO A  13
ILE A  12
GLY A  11
TYR A   9
None
1.07A 2jkjF-4lp7A:
undetectable
2jkjF-4lp7A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyp EXO-BETA-1,4-MANNOSI
DASE


(Rhizomucor
miehei)
no annotation 4 PRO A 266
PRO A 269
GLY A 271
TYR A 264
None
1.17A 2jkjF-4lypA:
undetectable
2jkjF-4lypA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ma5 PHOSPHORIBOSYLAMINOI
MIDAZOLE
CARBOXYLASE, ATPASE
SUBUNIT


(Francisella
tularensis)
PF02222
(ATP-grasp)
4 PRO A 262
ILE A 287
GLY A 242
TYR A 240
None
1.11A 2jkjF-4ma5A:
undetectable
2jkjF-4ma5A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q95 HRAS-LIKE SUPPRESSOR
3, LECITHIN RETINOL
ACYLTRANSFERASE


(Homo sapiens;
Mus musculus)
PF04970
(LRAT)
4 PRO A   9
PRO A  11
ILE A 105
GLY A  12
None
1.08A 2jkjF-4q95A:
undetectable
2jkjF-4q95A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qre METHIONYL-TRNA
SYNTHETASE


(Staphylococcus
aureus)
PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g)
4 PRO A 156
PRO A 143
ILE A 150
GLY A 153
None
1.00A 2jkjF-4qreA:
undetectable
2jkjF-4qreA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10


(Homo sapiens)
PF00326
(Peptidase_S9)
PF00930
(DPPIV_N)
4 PRO A 275
PRO A 267
ILE A 266
GLY A 277
None
0.95A 2jkjF-4wjlA:
undetectable
2jkjF-4wjlA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xac EVDO2

(Micromonospora
carbonacea)
PF05721
(PhyH)
4 PRO A  70
PRO A  73
ILE A  60
GLY A  62
None
1.12A 2jkjF-4xacA:
1.2
2jkjF-4xacA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E


(Streptococcus
mutans)
PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C)
4 PRO A 212
ILE A 202
GLY A 200
TYR A 217
None
0.83A 2jkjF-4xb3A:
undetectable
2jkjF-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E


(Streptococcus
mutans)
PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C)
4 PRO A 212
ILE A 207
GLY A 200
TYR A 217
None
1.15A 2jkjF-4xb3A:
undetectable
2jkjF-4xb3A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xci THERMOSOME SUBUNIT
ALPHA


(Sulfolobus
solfataricus)
PF00118
(Cpn60_TCP1)
4 PRO A 192
PRO A 194
GLY A 196
TYR A 198
None
1.05A 2jkjF-4xciA:
undetectable
2jkjF-4xciA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xqk LLABIII

(Lactococcus
lactis)
PF00271
(Helicase_C)
PF02384
(N6_Mtase)
PF04851
(ResIII)
PF13156
(Mrr_cat_2)
4 PRO A1020
PRO A 903
ILE A1015
GLY A1017
None
1.02A 2jkjF-4xqkA:
undetectable
2jkjF-4xqkA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4n PUTATIVE RIBOSE
1,5-BISPHOSPHATE
ISOMERASE


(Methanotorris
igneus)
PF01946
(Thi4)
4 PRO A  39
ILE A 240
GLY A 242
TYR A 245
48H  A 302 (-3.4A)
None
None
None
1.12A 2jkjF-4y4nA:
undetectable
2jkjF-4y4nA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aeb LRA-12

(uncultured
bacterium BLR12)
PF00753
(Lactamase_B)
4 PRO A  41
PRO A  44
ILE A  55
GLY A  56
None
1.16A 2jkjF-5aebA:
undetectable
2jkjF-5aebA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus)
PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N)
4 PRO A 270
PRO A 183
ILE A 182
GLY A 263
None
1.08A 2jkjF-5df0A:
undetectable
2jkjF-5df0A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e76 SUSD-LIKE PROTEIN
BACOVA_02651


(Bacteroides
ovatus)
PF07980
(SusD_RagB)
PF14322
(SusD-like_3)
4 PRO A  85
PRO A  69
ILE A  70
GLY A  73
None
1.14A 2jkjF-5e76A:
undetectable
2jkjF-5e76A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ffj ENDONUCLEASE AND
METHYLASE LLAGI


(Lactococcus
lactis)
PF00271
(Helicase_C)
PF02384
(N6_Mtase)
PF04851
(ResIII)
4 PRO A1020
PRO A 903
ILE A1015
GLY A1017
None
1.10A 2jkjF-5ffjA:
undetectable
2jkjF-5ffjA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fol LEUCYL-TRNA
SYNTHETASE


(Cryptosporidium
muris)
no annotation 4 PRO A 303
ILE A 392
GLY A 388
TYR A 307
None
1.03A 2jkjF-5folA:
undetectable
2jkjF-5folA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpr CHITINASE

(Ostrinia
furnacalis)
PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N)
4 PRO A 273
PRO A 186
ILE A 185
GLY A 266
PRO  A 273 ( 1.1A)
PRO  A 186 ( 1.1A)
ILE  A 185 ( 0.7A)
GLY  A 266 ( 0.0A)
1.08A 2jkjF-5gprA:
undetectable
2jkjF-5gprA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1s 50S RIBOSOMAL
PROTEIN L13,
CHLOROPLASTIC


(Spinacia
oleracea)
PF00572
(Ribosomal_L13)
4 PRO L 145
ILE L 135
GLY L 137
TYR L 143
C  A 568 ( 4.7A)
None
None
None
1.15A 2jkjF-5h1sL:
undetectable
2jkjF-5h1sL:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5l GLUTATHIONE
S-TRANSFERASE S2


(Nilaparvata
lugens)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 PRO A  17
ILE A 159
GLY A  13
TYR A   8
None
None
PEG  A 302 (-3.5A)
GSH  A 301 ( 4.9A)
1.12A 2jkjF-5h5lA:
undetectable
2jkjF-5h5lA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hkq CDII IMMUNITY
PROTEIN


(Escherichia
coli)
no annotation 4 PRO I  76
ILE I  46
GLY I  49
TYR I  75
None
1.10A 2jkjF-5hkqI:
undetectable
2jkjF-5hkqI:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN


(Escherichia
coli;
Homo sapiens)
PF13416
(SBP_bac_8)
4 PRO A 657
PRO A 625
GLY A 626
TYR A 658
None
1.12A 2jkjF-5hzwA:
undetectable
2jkjF-5hzwA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE


(Physcomitrella
patens)
PF00316
(FBPase)
5 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
None
1.44A 2jkjF-5iz1A:
undetectable
2jkjF-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jm6 AMINOPEPTIDASE-LIKE
PROTEIN


(Chaetomium
thermophilum)
PF02127
(Peptidase_M18)
4 PRO A  51
PRO A 496
ILE A 479
GLY A 499
None
1.16A 2jkjF-5jm6A:
undetectable
2jkjF-5jm6A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kym 1-ACYL-SN-GLYCEROL-3
-PHOSPHATE
ACYLTRANSFERASE


(Thermotoga
maritima)
PF01553
(Acyltransferase)
4 PRO A 196
PRO A 161
GLY A 163
TYR A 192
None
1.02A 2jkjF-5kymA:
undetectable
2jkjF-5kymA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lq8 PUTATIVE PHOSPHONATE
BINDING PROTEIN FOR
ABC TRANSPORTER


(Prochlorococcus
marinus)
no annotation 4 PRO A  12
PRO A  42
ILE A  41
GLY A   9
None
1.07A 2jkjF-5lq8A:
undetectable
2jkjF-5lq8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m45 ACETONE CARBOXYLASE
BETA SUBUNIT


(Xanthobacter
autotrophicus)
PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N)
4 PRO B 286
ILE B 287
GLY B 289
TYR B 471
None
1.04A 2jkjF-5m45B:
undetectable
2jkjF-5m45B:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN


(Rhodobacter
sphaeroides)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 PRO A  91
PRO A  96
GLY A  97
TYR A  99
None
1.08A 2jkjF-5nv3A:
undetectable
2jkjF-5nv3A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyn DEHYDRATASE,
ILVD/EDD FAMILY


(Caulobacter
vibrioides)
no annotation 4 PRO A  46
PRO A  82
ILE A  50
GLY A  49
None
1.16A 2jkjF-5oynA:
undetectable
2jkjF-5oynA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t89 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1


(Homo sapiens)
PF00047
(ig)
PF07679
(I-set)
PF13927
(Ig_3)
4 PRO X 470
ILE X 529
GLY X 531
TYR X 533
None
1.10A 2jkjF-5t89X:
undetectable
2jkjF-5t89X:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgz 26S PROTEASOME
REGULATORY SUBUNIT 7
26S PROTEASOME
REGULATORY SUBUNIT 4


(Homo sapiens;
Homo sapiens)
no annotation
no annotation
4 PRO A 152
ILE A 149
GLY A 141
TYR B 132
None
1.12A 2jkjF-5vgzA:
undetectable
2jkjF-5vgzA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byi BETA-MANNOSIDASE

(Xanthomonas
citri)
no annotation 4 PRO A 889
PRO A 629
ILE A 622
GLY A 627
None
1.10A 2jkjF-6byiA:
undetectable
2jkjF-6byiA:
undetectable