SIMILAR PATTERNS OF AMINO ACIDS FOR 2JKJ_D_CLMD1142
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a87 | COLICIN N (Escherichiacoli) |
PF01024(Colicin) | 4 | PRO A 101PRO A 106GLY A 107TYR A 109 | None | 0.82A | 2jkjD-1a87A:undetectable | 2jkjD-1a87A:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b6r | PROTEIN(N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDESYNTHETASE) (Escherichiacoli) |
PF02222(ATP-grasp) | 4 | PRO A 241ILE A 266GLY A 221TYR A 219 | None | 1.12A | 2jkjD-1b6rA:0.0 | 2jkjD-1b6rA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dcu | FRUCTOSE-1,6-BISPHOSPHATASE (Pisum sativum) |
PF00316(FBPase) | 4 | PRO A 180ILE A 143GLY A 145TYR A 147 | None | 1.06A | 2jkjD-1dcuA:0.0 | 2jkjD-1dcuA:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ee8 | MUTM (FPG) PROTEIN (Thermusthermophilus) |
PF01149(Fapy_DNA_glyco)PF06827(zf-FPG_IleRS)PF06831(H2TH) | 4 | PRO A 1PRO A 4GLY A 206TYR A 214 | None | 1.18A | 2jkjD-1ee8A:0.0 | 2jkjD-1ee8A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m5y | SURVIVAL PROTEINSURA (Escherichiacoli) |
PF00639(Rotamase)PF09312(SurA_N)PF13616(Rotamase_3) | 4 | PRO A 184PRO A 182ILE A 181GLY A 264 | None | 0.93A | 2jkjD-1m5yA:0.2 | 2jkjD-1m5yA:14.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1na6 | RESTRICTIONENDONUCLEASE ECORII (Escherichiacoli) |
PF09019(EcoRII-C)PF09217(EcoRII-N) | 4 | PRO A 371PRO A 214ILE A 393GLY A 390 | None | 1.06A | 2jkjD-1na6A:0.0 | 2jkjD-1na6A:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nvt | SHIKIMATE5'-DEHYDROGENASE (Methanocaldococcusjannaschii) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 4 | PRO A 27ILE A 17GLY A 15TYR A 43 | None | 1.10A | 2jkjD-1nvtA:0.0 | 2jkjD-1nvtA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ow0 | IMMUNOGLOBULIN ALPHAFC RECEPTOR (Homo sapiens) |
no annotation | 4 | PRO C 180ILE C 42GLY C 75TYR C 181 | None | 1.08A | 2jkjD-1ow0C:0.0 | 2jkjD-1ow0C:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pby | QUINOHEMOPROTEINAMINE DEHYDROGENASE60 KDA SUBUNIT (Paracoccusdenitrificans) |
PF09098(Dehyd-heme_bind)PF09099(Qn_am_d_aIII)PF09100(Qn_am_d_aIV)PF14930(Qn_am_d_aII) | 4 | PRO A 378PRO A 375ILE A 374GLY A 368 | None | 1.16A | 2jkjD-1pbyA:0.0 | 2jkjD-1pbyA:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi9 | PROTEIN (VANADIUMBROMOPEROXIDASE) (Ascophyllumnodosum) |
no annotation | 4 | PRO A 98PRO A 252ILE A 246GLY A 250 | None | 1.05A | 2jkjD-1qi9A:undetectable | 2jkjD-1qi9A:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sky | F1-ATPASE (Bacillus sp.PS3) |
PF00006(ATP-synt_ab)PF00306(ATP-synt_ab_C)PF02874(ATP-synt_ab_N) | 4 | PRO B 110PRO B 239ILE B 260GLY B 242 | None | 1.00A | 2jkjD-1skyB:undetectable | 2jkjD-1skyB:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tg5 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Arabidopsisthaliana) |
PF00903(Glyoxalase) | 4 | PRO A 318ILE A 359GLY A 345TYR A 322 | None | 1.13A | 2jkjD-1tg5A:undetectable | 2jkjD-1tg5A:15.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ut1 | DR HEMAGGLUTININSTRUCTURAL SUBUNIT (Escherichiacoli) |
PF04619(Adhesin_Dr) | 5 | PRO A 40PRO A 43ILE A 111GLY A 113TYR A 115 | EDO A1143 ( 4.3A)NoneNoneNoneNone | 0.53A | 2jkjD-1ut1A:27.2 | 2jkjD-1ut1A:99.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5f | PYRUVATE OXIDASE (Aerococcusviridans) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | PRO A 189PRO A 192ILE A 317GLY A 319 | None | 1.05A | 2jkjD-1v5fA:undetectable | 2jkjD-1v5fA:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wjm | BETA-SPECTRIN III (Homo sapiens) |
PF15410(PH_9) | 4 | PRO A 58PRO A 64GLY A 45TYR A 47 | None | 1.09A | 2jkjD-1wjmA:undetectable | 2jkjD-1wjmA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xsz | GUANINE NUCLEOTIDEEXCHANGE PROTEIN (Legionellapneumophila) |
PF01369(Sec7) | 4 | PRO A 201PRO A 101ILE A 107GLY A 102 | None | 1.10A | 2jkjD-1xszA:undetectable | 2jkjD-1xszA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ywk | 4-DEOXY-L-THREO-5-HEXOSULOSE-URONATEKETOL-ISOMERASE 1 (Enterococcusfaecalis) |
PF04962(KduI) | 4 | PRO A1009PRO A1221ILE A1242GLY A1219 | None | 1.15A | 2jkjD-1ywkA:1.5 | 2jkjD-1ywkA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z5v | TUBULIN GAMMA-1CHAIN (Homo sapiens) |
PF00091(Tubulin)PF03953(Tubulin_C) | 4 | PRO A 365ILE A 36GLY A 30TYR A 366 | None | 1.11A | 2jkjD-1z5vA:undetectable | 2jkjD-1z5vA:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zr9 | ZINC FINGER PROTEIN593 (Homo sapiens) |
PF12171(zf-C2H2_jaz) | 4 | PRO A 35PRO A 38ILE A 53GLY A 39 | None | 1.16A | 2jkjD-1zr9A:undetectable | 2jkjD-1zr9A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bru | NAD(P)TRANSHYDROGENASESUBUNIT ALPHA (Escherichiacoli) |
PF01262(AlaDh_PNT_C)PF05222(AlaDh_PNT_N) | 4 | PRO A1095PRO A1259ILE A1258GLY A1260 | None | 1.04A | 2jkjD-2bruA:undetectable | 2jkjD-2bruA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2czt | PROSTAGLANDIN-H2D-ISOMERASE (Mus musculus) |
PF00061(Lipocalin) | 4 | PRO A 98PRO A 102GLY A 103TYR A 105 | None | 0.58A | 2jkjD-2cztA:undetectable | 2jkjD-2cztA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2egg | SHIKIMATE5-DEHYDROGENASE (Geobacilluskaustophilus) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 4 | PRO A 39ILE A 29GLY A 27TYR A 55 | None | 1.18A | 2jkjD-2eggA:undetectable | 2jkjD-2eggA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eyq | TRANSCRIPTION-REPAIRCOUPLING FACTOR (Escherichiacoli) |
PF00270(DEAD)PF00271(Helicase_C)PF02559(CarD_CdnL_TRCF)PF03461(TRCF) | 4 | PRO A 522ILE A 504GLY A 506TYR A 508 | None | 0.70A | 2jkjD-2eyqA:undetectable | 2jkjD-2eyqA:10.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsb | RASGTPASE-ACTIVATINGPROTEIN 1 (Homo sapiens) |
PF00017(SH2) | 4 | PRO A 45PRO A 50GLY A 51TYR A 53 | None | 1.05A | 2jkjD-2gsbA:undetectable | 2jkjD-2gsbA:24.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i76 | HYPOTHETICAL PROTEIN (Thermotogamaritima) |
PF10728(DUF2520) | 4 | PRO A 105ILE A 103GLY A 125TYR A 158 | NDP A 301 (-4.0A)NoneNoneNone | 1.06A | 2jkjD-2i76A:undetectable | 2jkjD-2i76A:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mau | WRIGHTIDE R1 (Wrightiareligiosa) |
no annotation | 4 | PRO A 23ILE A 25GLY A 27TYR A 7 | None | 1.16A | 2jkjD-2mauA:undetectable | 2jkjD-2mauA:8.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2my9 | RETINOIC ACIDRECEPTOR RESPONDERPROTEIN 3 (Homo sapiens) |
PF04970(LRAT) | 4 | PRO A 8PRO A 10ILE A 93GLY A 11 | None | 0.96A | 2jkjD-2my9A:undetectable | 2jkjD-2my9A:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pp3 | L-TALARATE/GALACTARATE DEHYDRATASE (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | PRO A 300PRO A 303ILE A 137GLY A 307 | None | 1.12A | 2jkjD-2pp3A:undetectable | 2jkjD-2pp3A:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pv2 | CHAPERONE SURA (Escherichiacoli) |
PF00639(Rotamase) | 4 | PRO A 184PRO A 182ILE A 181GLY A 264 | None | 0.98A | 2jkjD-2pv2A:undetectable | 2jkjD-2pv2A:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1d | 2-KETO-3-DEOXY-D-ARABINONATE DEHYDRATASE (Sulfolobussolfataricus) |
PF01557(FAA_hydrolase) | 4 | PRO X 30PRO X 73ILE X 251GLY X 249 | None | 1.03A | 2jkjD-2q1dX:undetectable | 2jkjD-2q1dX:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uu7 | GLUTAMINE SYNTHETASE (Canis lupus) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 4 | PRO A 199PRO A 146GLY A 148TYR A 171 | None | 1.17A | 2jkjD-2uu7A:undetectable | 2jkjD-2uu7A:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v84 | SPERMIDINE/PUTRESCINE ABC TRANSPORTER,PERIPLASMIC BINDINGPROTEIN (Treponemapallidum) |
PF13416(SBP_bac_8) | 4 | PRO A 236PRO A 230ILE A 116GLY A 115 | None | 1.06A | 2jkjD-2v84A:undetectable | 2jkjD-2v84A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wbp | L-ARGININEBETA-HYDROXYLASE (Streptomycesvinaceus) |
PF02668(TauD) | 4 | PRO A 263PRO A 200ILE A 292GLY A 198 | None | 1.05A | 2jkjD-2wbpA:undetectable | 2jkjD-2wbpA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wfg | CYTOSOLICLEUCYL-TRNASYNTHETASE (Candidaalbicans) |
PF00133(tRNA-synt_1) | 4 | PRO A 332ILE A 381GLY A 377TYR A 336 | None | 1.08A | 2jkjD-2wfgA:undetectable | 2jkjD-2wfgA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 4 | PRO A 280PRO A 193ILE A 192GLY A 273 | None | 1.15A | 2jkjD-2wk2A:undetectable | 2jkjD-2wk2A:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ydy | METHIONINEADENOSYLTRANSFERASE2 SUBUNIT BETA (Homo sapiens) |
PF04321(RmlD_sub_bind) | 5 | PRO A 221PRO A 310ILE A 313GLY A 314TYR A 186 | None | 1.48A | 2jkjD-2ydyA:undetectable | 2jkjD-2ydyA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yp2 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | PRO A 227PRO A 185ILE A 217GLY A 218 | None | 1.17A | 2jkjD-2yp2A:undetectable | 2jkjD-2yp2A:14.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zoo | PROBABLE NITRITEREDUCTASE (Pseudoalteromonashaloplanktis) |
PF00034(Cytochrom_C)PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 4 | PRO A 367PRO A 362GLY A 363TYR A 400 | HEM A 600 (-4.5A)SUC A 700 (-4.4A)SUC A 700 ( 3.8A)None | 1.11A | 2jkjD-2zooA:undetectable | 2jkjD-2zooA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5r | BENZALACETONESYNTHASE (Rheum palmatum) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | PRO A 265PRO A 300ILE A 207GLY A 298 | NoneNoneHC4 A 400 ( 4.5A)None | 1.13A | 2jkjD-3a5rA:undetectable | 2jkjD-3a5rA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9e | CHITINASE A (Vibrio harveyi) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 4 | PRO A 280PRO A 194ILE A 193GLY A 273 | None | 1.05A | 2jkjD-3b9eA:undetectable | 2jkjD-3b9eA:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cdk | SUCCINYL-COA:3-KETOACID-COENZYME ATRANSFERASE SUBUNITA (Bacillussubtilis) |
PF01144(CoA_trans) | 4 | PRO A 208PRO A 178ILE A 179TYR A 211 | None | 0.98A | 2jkjD-3cdkA:undetectable | 2jkjD-3cdkA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgw | LPPG:FO2-PHOSPHO-L-LACTATETRANSFERASE (Methanosarcinamazei) |
PF01933(UPF0052) | 4 | PRO A 194PRO A 200ILE A 165TYR A 251 | None | 1.16A | 2jkjD-3cgwA:undetectable | 2jkjD-3cgwA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3es4 | UNCHARACTERIZEDPROTEIN DUF861 WITHA RMLC-LIKE CUPINFOLD (Agrobacteriumfabrum) |
PF05899(Cupin_3) | 4 | PRO A 16PRO A 19GLY A 26TYR A 28 | None | 0.95A | 2jkjD-3es4A:undetectable | 2jkjD-3es4A:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f6u | VITAMIN K-DEPENDENTPROTEIN C HEAVYCHAIN (Homo sapiens) |
PF00089(Trypsin) | 4 | PRO H 164PRO H 161ILE H 184GLY H 184 | None | 1.13A | 2jkjD-3f6uH:undetectable | 2jkjD-3f6uH:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1n | PROBABLE GLUTATHIONES-TRANSFERASE (Bordetellabronchiseptica) |
PF14497(GST_C_3) | 4 | PRO A 56ILE A 223GLY A 13TYR A 7 | None CL A 234 (-4.2A) CL A 234 (-3.6A)None | 1.08A | 2jkjD-3h1nA:undetectable | 2jkjD-3h1nA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hx3 | RETINALDEHYDE-BINDING PROTEIN 1 (Homo sapiens) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 4 | PRO A 145ILE A 140GLY A 143TYR A 296 | None | 1.01A | 2jkjD-3hx3A:undetectable | 2jkjD-3hx3A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jyo | QUINATE/SHIKIMATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF08501(Shikimate_dh_N) | 4 | PRO A 20ILE A 10GLY A 8TYR A 36 | None | 1.16A | 2jkjD-3jyoA:undetectable | 2jkjD-3jyoA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kes | NUCLEOPORIN NUP145 (Saccharomycescerevisiae) |
PF04096(Nucleoporin2) | 4 | PRO A 555PRO A 593GLY A 596TYR A 554 | NoneEDO A 7 ( 4.4A)NoneNone | 1.09A | 2jkjD-3kesA:undetectable | 2jkjD-3kesA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kyd | SUMO-ACTIVATINGENZYME SUBUNIT 1SUMO-ACTIVATINGENZYME SUBUNIT 2 (Homo sapiens;Homo sapiens) |
PF00899(ThiF)PF00899(ThiF)PF14732(UAE_UbL) | 4 | PRO B 85PRO A 76GLY A 77TYR B 84 | None | 1.11A | 2jkjD-3kydB:undetectable | 2jkjD-3kydB:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nd1 | PRECORRIN-6ASYNTHASE/COBFPROTEIN (Rhodobactercapsulatus) |
PF00590(TP_methylase) | 4 | PRO A 212PRO A 14ILE A 50GLY A 12 | None | 0.89A | 2jkjD-3nd1A:undetectable | 2jkjD-3nd1A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ps5 | TYROSINE-PROTEINPHOSPHATASENON-RECEPTOR TYPE 6 (Homo sapiens) |
PF00017(SH2)PF00102(Y_phosphatase) | 4 | PRO A 268PRO A 297ILE A 296GLY A 298 | None | 1.16A | 2jkjD-3ps5A:undetectable | 2jkjD-3ps5A:14.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tnl | SHIKIMATEDEHYDROGENASE (Listeriamonocytogenes) |
PF08501(Shikimate_dh_N) | 4 | PRO A 29ILE A 19GLY A 17TYR A 45 | None | 1.12A | 2jkjD-3tnlA:undetectable | 2jkjD-3tnlA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsc | PUTATIVEOXIDOREDUCTASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | PRO A 48PRO A 44ILE A 127TYR A 49 | NoneNoneNAD A 274 (-3.8A)NAD A 274 ( 4.8A) | 1.04A | 2jkjD-3tscA:undetectable | 2jkjD-3tscA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vnn | DNA LIGASE 4 (Homo sapiens) |
PF01068(DNA_ligase_A_M) | 4 | PRO A 397ILE A 396GLY A 398TYR A 335 | None | 1.09A | 2jkjD-3vnnA:undetectable | 2jkjD-3vnnA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3r | ENOLASE (Bacillussubtilis) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | PRO A 173ILE A 422GLY A 421TYR A 419 | None | 1.18A | 2jkjD-4a3rA:undetectable | 2jkjD-4a3rA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aie | GLUCAN1,6-ALPHA-GLUCOSIDASE (Lactobacillusacidophilus) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | PRO A 220PRO A 216GLY A 204TYR A 221 | None | 1.08A | 2jkjD-4aieA:undetectable | 2jkjD-4aieA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ap3 | STEROIDMONOOXYGENASE (Rhodococcusrhodochrous) |
PF00743(FMO-like) | 4 | PRO A 99PRO A 66ILE A 209GLY A 67 | None | 1.10A | 2jkjD-4ap3A:undetectable | 2jkjD-4ap3A:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7p | RALF (Legionellapneumophila) |
PF01369(Sec7) | 4 | PRO A 201PRO A 101ILE A 107GLY A 102 | None | 1.05A | 2jkjD-4c7pA:undetectable | 2jkjD-4c7pA:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cg1 | CUTINASE (Thermobifidafusca) |
PF12740(Chlorophyllase2) | 4 | PRO A 180PRO A 154ILE A 170GLY A 172 | None | 1.10A | 2jkjD-4cg1A:undetectable | 2jkjD-4cg1A:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d4g | APNAA1 (Planktothrixagardhii) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | PRO A 86PRO A 83ILE A 153TYR A 88 | None | 1.16A | 2jkjD-4d4gA:undetectable | 2jkjD-4d4gA:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7q | RALF,PROLINE/BETAINETRANSPORTER (Legionellapneumophila;Rickettsiaprowazekii) |
PF01369(Sec7) | 4 | PRO A 201PRO A 101ILE A 107GLY A 102 | NO3 A1348 ( 4.6A)NoneNoneNone | 1.03A | 2jkjD-4d7qA:undetectable | 2jkjD-4d7qA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7r | PROLINE/BETAINETRANSPORTER, RALF (Legionellapneumophila;Rickettsiaprowazekii) |
PF01369(Sec7) | 4 | PRO A 199PRO A 98ILE A 104GLY A 99 | None | 1.09A | 2jkjD-4d7rA:undetectable | 2jkjD-4d7rA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4j | ARGININE DEIMINASE (Mycoplasmapenetrans) |
PF02274(Amidinotransf) | 4 | PRO A 197PRO A 72ILE A 99GLY A 73 | None | 1.10A | 2jkjD-4e4jA:undetectable | 2jkjD-4e4jA:16.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eb0 | LCC (unculturedbacterium) |
PF12695(Abhydrolase_5) | 4 | PRO A 214PRO A 189ILE A 204GLY A 206 | None | 1.12A | 2jkjD-4eb0A:undetectable | 2jkjD-4eb0A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fa0 | GROUP XVIPHOSPHOLIPASE A1/A2 (Homo sapiens) |
PF04970(LRAT) | 4 | PRO A 8PRO A 10ILE A 93GLY A 11 | None | 1.13A | 2jkjD-4fa0A:undetectable | 2jkjD-4fa0A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga4 | PUTATIVE THYMIDINEPHOSPHORYLASE (Thermococcuskodakarensis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | PRO A 323ILE A 428GLY A 321TYR A 319 | None | 0.95A | 2jkjD-4ga4A:undetectable | 2jkjD-4ga4A:14.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga6 | PUTATIVE THYMIDINEPHOSPHORYLASE (Thermococcuskodakarensis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | PRO A 323ILE A 428GLY A 321TYR A 319 | None | 1.02A | 2jkjD-4ga6A:undetectable | 2jkjD-4ga6A:12.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jvw | IG MU CHAIN C REGIONSECRETED FORM (Mus musculus) |
PF07654(C1-set) | 4 | PRO A 507PRO A 512GLY A 513TYR A 515 | None | 0.98A | 2jkjD-4jvwA:undetectable | 2jkjD-4jvwA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lp7 | MATRIX PROTEIN M (Humanmetapneumovirus) |
PF03393(Pneumo_matrix) | 4 | PRO A 13ILE A 12GLY A 11TYR A 9 | None | 1.07A | 2jkjD-4lp7A:undetectable | 2jkjD-4lp7A:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lyp | EXO-BETA-1,4-MANNOSIDASE (Rhizomucormiehei) |
no annotation | 4 | PRO A 266PRO A 269GLY A 271TYR A 264 | None | 1.17A | 2jkjD-4lypA:undetectable | 2jkjD-4lypA:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ma5 | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXYLASE, ATPASESUBUNIT (Francisellatularensis) |
PF02222(ATP-grasp) | 4 | PRO A 262ILE A 287GLY A 242TYR A 240 | None | 1.11A | 2jkjD-4ma5A:undetectable | 2jkjD-4ma5A:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q52 | UNCHARACTERIZEDPROTEIN (Chitinophagapinensis) |
PF12306(PixA) | 4 | PRO A 47ILE A 102GLY A 171TYR A 187 | None | 1.12A | 2jkjD-4q52A:undetectable | 2jkjD-4q52A:24.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q95 | HRAS-LIKE SUPPRESSOR3, LECITHIN RETINOLACYLTRANSFERASE (Homo sapiens;Mus musculus) |
PF04970(LRAT) | 4 | PRO A 9PRO A 11ILE A 105GLY A 12 | None | 1.09A | 2jkjD-4q95A:undetectable | 2jkjD-4q95A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qre | METHIONYL-TRNASYNTHETASE (Staphylococcusaureus) |
PF08264(Anticodon_1)PF09334(tRNA-synt_1g) | 4 | PRO A 156PRO A 143ILE A 150GLY A 153 | None | 0.99A | 2jkjD-4qreA:undetectable | 2jkjD-4qreA:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjl | INACTIVE DIPEPTIDYLPEPTIDASE 10 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | PRO A 275PRO A 267ILE A 266GLY A 277 | None | 0.95A | 2jkjD-4wjlA:undetectable | 2jkjD-4wjlA:11.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xac | EVDO2 (Micromonosporacarbonacea) |
PF05721(PhyH) | 4 | PRO A 70PRO A 73ILE A 60GLY A 62 | None | 1.12A | 2jkjD-4xacA:undetectable | 2jkjD-4xacA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb3 | GLUCAN1,6-ALPHA-GLUCOSIDASE (Streptococcusmutans) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | PRO A 212ILE A 202GLY A 200TYR A 217 | None | 0.83A | 2jkjD-4xb3A:undetectable | 2jkjD-4xb3A:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb3 | GLUCAN1,6-ALPHA-GLUCOSIDASE (Streptococcusmutans) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | PRO A 212ILE A 207GLY A 200TYR A 217 | None | 1.15A | 2jkjD-4xb3A:undetectable | 2jkjD-4xb3A:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xci | THERMOSOME SUBUNITALPHA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 4 | PRO A 192PRO A 194GLY A 196TYR A 198 | None | 1.05A | 2jkjD-4xciA:undetectable | 2jkjD-4xciA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xqk | LLABIII (Lactococcuslactis) |
PF00271(Helicase_C)PF02384(N6_Mtase)PF04851(ResIII)PF13156(Mrr_cat_2) | 4 | PRO A1020PRO A 903ILE A1015GLY A1017 | None | 1.03A | 2jkjD-4xqkA:undetectable | 2jkjD-4xqkA:7.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y4n | PUTATIVE RIBOSE1,5-BISPHOSPHATEISOMERASE (Methanotorrisigneus) |
PF01946(Thi4) | 4 | PRO A 39ILE A 240GLY A 242TYR A 245 | 48H A 302 (-3.4A)NoneNoneNone | 1.12A | 2jkjD-4y4nA:undetectable | 2jkjD-4y4nA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aeb | LRA-12 (unculturedbacterium BLR12) |
PF00753(Lactamase_B) | 4 | PRO A 41PRO A 44ILE A 55GLY A 56 | None | 1.15A | 2jkjD-5aebA:undetectable | 2jkjD-5aebA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5df0 | AC-CHIA (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 4 | PRO A 270PRO A 183ILE A 182GLY A 263 | None | 1.08A | 2jkjD-5df0A:undetectable | 2jkjD-5df0A:14.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e76 | SUSD-LIKE PROTEINBACOVA_02651 (Bacteroidesovatus) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | PRO A 85PRO A 69ILE A 70GLY A 73 | None | 1.14A | 2jkjD-5e76A:undetectable | 2jkjD-5e76A:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffj | ENDONUCLEASE ANDMETHYLASE LLAGI (Lactococcuslactis) |
PF00271(Helicase_C)PF02384(N6_Mtase)PF04851(ResIII) | 4 | PRO A1020PRO A 903ILE A1015GLY A1017 | None | 1.11A | 2jkjD-5ffjA:undetectable | 2jkjD-5ffjA:7.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fol | LEUCYL-TRNASYNTHETASE (Cryptosporidiummuris) |
no annotation | 4 | PRO A 303ILE A 392GLY A 388TYR A 307 | None | 1.03A | 2jkjD-5folA:undetectable | 2jkjD-5folA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpr | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 4 | PRO A 273PRO A 186ILE A 185GLY A 266 | PRO A 273 ( 1.1A)PRO A 186 ( 1.1A)ILE A 185 ( 0.7A)GLY A 266 ( 0.0A) | 1.08A | 2jkjD-5gprA:undetectable | 2jkjD-5gprA:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5l | GLUTATHIONES-TRANSFERASE S2 (Nilaparvatalugens) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | PRO A 17ILE A 159GLY A 13TYR A 8 | NoneNonePEG A 302 (-3.5A)GSH A 301 ( 4.9A) | 1.12A | 2jkjD-5h5lA:undetectable | 2jkjD-5h5lA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hkq | CDII IMMUNITYPROTEIN (Escherichiacoli) |
no annotation | 4 | PRO I 76ILE I 46GLY I 49TYR I 75 | None | 1.10A | 2jkjD-5hkqI:undetectable | 2jkjD-5hkqI:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzw | MALTOSE-BINDINGPERIPLASMICPROTEIN,ENDOGLIN (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8) | 4 | PRO A 657PRO A 625GLY A 626TYR A 658 | None | 1.12A | 2jkjD-5hzwA:undetectable | 2jkjD-5hzwA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iz1 | FRUCTOSE-1,6-BISPHOSPHATASE (Physcomitrellapatens) |
PF00316(FBPase) | 5 | PRO A 248PRO A 376ILE A 214GLY A 216TYR A 218 | None | 1.45A | 2jkjD-5iz1A:undetectable | 2jkjD-5iz1A:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jm6 | AMINOPEPTIDASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF02127(Peptidase_M18) | 4 | PRO A 51PRO A 496ILE A 479GLY A 499 | None | 1.15A | 2jkjD-5jm6A:undetectable | 2jkjD-5jm6A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kym | 1-ACYL-SN-GLYCEROL-3-PHOSPHATEACYLTRANSFERASE (Thermotogamaritima) |
PF01553(Acyltransferase) | 4 | PRO A 196PRO A 161GLY A 163TYR A 192 | None | 1.02A | 2jkjD-5kymA:undetectable | 2jkjD-5kymA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lq8 | PUTATIVE PHOSPHONATEBINDING PROTEIN FORABC TRANSPORTER (Prochlorococcusmarinus) |
no annotation | 4 | PRO A 12PRO A 42ILE A 41GLY A 9 | None | 1.07A | 2jkjD-5lq8A:undetectable | 2jkjD-5lq8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m45 | ACETONE CARBOXYLASEBETA SUBUNIT (Xanthobacterautotrophicus) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 4 | PRO B 286ILE B 287GLY B 289TYR B 471 | None | 1.04A | 2jkjD-5m45B:undetectable | 2jkjD-5m45B:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv3 | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Rhodobactersphaeroides) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | PRO A 91PRO A 96GLY A 97TYR A 99 | None | 1.08A | 2jkjD-5nv3A:undetectable | 2jkjD-5nv3A:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oyn | DEHYDRATASE,ILVD/EDD FAMILY (Caulobactervibrioides) |
no annotation | 4 | PRO A 46PRO A 82ILE A 50GLY A 49 | None | 1.16A | 2jkjD-5oynA:undetectable | 2jkjD-5oynA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t89 | VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 1 (Homo sapiens) |
PF00047(ig)PF07679(I-set)PF13927(Ig_3) | 4 | PRO X 470ILE X 529GLY X 531TYR X 533 | None | 1.10A | 2jkjD-5t89X:undetectable | 2jkjD-5t89X:13.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgz | 26S PROTEASOMEREGULATORY SUBUNIT 726S PROTEASOMEREGULATORY SUBUNIT 4 (Homo sapiens;Homo sapiens) |
no annotationno annotation | 4 | PRO A 152ILE A 149GLY A 141TYR B 132 | None | 1.12A | 2jkjD-5vgzA:undetectable | 2jkjD-5vgzA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byi | BETA-MANNOSIDASE (Xanthomonascitri) |
no annotation | 4 | PRO A 889PRO A 629ILE A 622GLY A 627 | None | 1.10A | 2jkjD-6byiA:undetectable | 2jkjD-6byiA:undetectable |