SIMILAR PATTERNS OF AMINO ACIDS FOR 2JAP_B_J01B1249_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c1d | L-PHENYLALANINEDEHYDROGENASE (Rhodococcus sp.) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ILE A 315ALA A 160ALA A 282THR A 153LEU A 190 | NoneNoneNoneNAI A 360 (-3.2A)None | 1.26A | 2japB-1c1dA:7.1 | 2japB-1c1dA:25.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbu | CYSTEINYL-TRNA(PRO)DEACYLASE (Haemophilusinfluenzae) |
PF04073(tRNA_edit) | 5 | LEU A 64SER A 78ILE A 79ALA A 75THR A 114 | NoneNoneNoneNone HG A 260 (-3.2A) | 1.24A | 2japB-1dbuA:undetectable | 2japB-1dbuA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dk2 | DNA POLYMERASE BETA (Rattusnorvegicus) |
PF14716(HHH_8) | 5 | LEU A 19ILE A 53ALA A 59VAL A 45ALA A 42 | None | 1.18A | 2japB-1dk2A:undetectable | 2japB-1dk2A:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e2z | CYTOCHROME F (Chlamydomonasreinhardtii) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 5 | LEU A 83VAL A 89ALA A 84LEU A 75TYR A 102 | None | 1.00A | 2japB-1e2zA:undetectable | 2japB-1e2zA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ij9 | VASCULAR CELLADHESION PROTEIN 1 (Homo sapiens) |
PF05790(C2-set)PF07679(I-set) | 5 | MET A 58LEU A 21ILE A 88ALA A 13TYR A 69 | None | 1.20A | 2japB-1ij9A:undetectable | 2japB-1ij9A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o94 | TRIMETHYLAMINEDEHYDROGENASE (Methylophilusmethylotrophus) |
PF00724(Oxidored_FMN)PF07992(Pyr_redox_2) | 5 | LEU A 417ILE A 672ALA A 486ALA A 397LEU A 393 | None | 1.19A | 2japB-1o94A:2.2 | 2japB-1o94A:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pie | GALACTOKINASE (Lactococcuslactis) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 5 | LEU A 39ILE A 219ALA A 387ALA A 54LEU A 357 | None | 1.22A | 2japB-1pieA:undetectable | 2japB-1pieA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q7l | AMINOACYLASE-1 (Homo sapiens) |
PF01546(Peptidase_M20) | 5 | LEU B 398ILE B 390VAL B 330ALA B 397LEU A 77 | None | 1.13A | 2japB-1q7lB:undetectable | 2japB-1q7lB:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q90 | APOCYTOCHROME F (Chlamydomonasreinhardtii) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 5 | LEU A 83VAL A 89ALA A 84LEU A 75TYR A 102 | None | 0.95A | 2japB-1q90A:undetectable | 2japB-1q90A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhl | PROTEIN (CELLDIVISION PROTEINMUKB) (Escherichiacoli) |
PF04310(MukB) | 5 | LEU A 90ALA A 46ALA A 50THR A 22LEU A 28 | None | 1.19A | 2japB-1qhlA:undetectable | 2japB-1qhlA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 5 | LEU A 93SER A 31ILE A 75ALA A 92LEU A 24 | None | 1.22A | 2japB-1sivA:undetectable | 2japB-1sivA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v0b | CELL DIVISIONCONTROL PROTEIN 2HOMOLOG (Plasmodiumfalciparum) |
PF00069(Pkinase) | 5 | LEU A 200ILE A 258VAL A 195ALA A 192LEU A 217 | None | 1.18A | 2japB-1v0bA:undetectable | 2japB-1v0bA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wao | SERINE/THREONINEPROTEIN PHOSPHATASE5 (Homo sapiens) |
PF00149(Metallophos)PF00515(TPR_1)PF08321(PPP5) | 5 | LEU 1 300ILE 1 344VAL 1 239THR 1 229LEU 1 226 | None | 1.06A | 2japB-1wao1:undetectable | 2japB-1wao1:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xbz | 3-KETO-L-GULONATE6-PHOSPHATEDECARBOXYLASE (Escherichiacoli) |
PF00215(OMPdecase) | 5 | LEU A 50ILE A 25ALA A 26VAL A 8TYR A 54 | None | 1.21A | 2japB-1xbzA:3.3 | 2japB-1xbzA:25.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xec | DECORIN (Bos taurus) |
PF01462(LRRNT)PF13855(LRR_8) | 5 | LEU A 223SER A 211VAL A 231THR A 239LEU A 197 | None | 1.10A | 2japB-1xecA:undetectable | 2japB-1xecA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a14 | INDOLETHYLAMINEN-METHYLTRANSFERASE (Homo sapiens) |
PF01234(NNMT_PNMT_TEMT) | 5 | LEU A 42ILE A 68VAL A 111ALA A 114LEU A 163 | NoneNoneNoneNoneSAH A4001 (-4.5A) | 1.21A | 2japB-2a14A:6.3 | 2japB-2a14A:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmb | FOLIC ACID SYNTHESISPROTEIN FOL1 (Saccharomycescerevisiae) |
PF00809(Pterin_bind)PF01288(HPPK) | 5 | LEU A 582ILE A 589ALA A 548ALA A 581LEU A 626 | None | 1.22A | 2japB-2bmbA:2.5 | 2japB-2bmbA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 5 | ILE A 242ALA A 159VAL A 165ALA A 139LEU A 260 | None | 1.17A | 2japB-2c3oA:2.3 | 2japB-2c3oA:13.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2co6 | PUTATIVE FIMBRIAEASSEMBLY CHAPERONE (Salmonellaenterica) |
PF00345(PapD_N)PF02753(PapD_C) | 5 | LEU B 16ILE B 42ALA B 99ALA B 124LEU B 76 | None | 1.21A | 2japB-2co6B:undetectable | 2japB-2co6B:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cx9 | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | ILE A 78VAL A 26ALA A 30THR A 88LEU A 210 | None | 1.00A | 2japB-2cx9A:undetectable | 2japB-2cx9A:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0d | 2-HYDROXY-6-OXO-7-METHYLOCTA-2,4-DIENOATE HYDROLASE (Pseudomonasfluorescens) |
PF00561(Abhydrolase_1) | 5 | LEU A 212ALA A 109VAL A 120ALA A 113LEU A 235 | None | 1.16A | 2japB-2d0dA:5.7 | 2japB-2d0dA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dkn | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (Pseudomonas sp.B-0831) |
PF13561(adh_short_C2) | 5 | SER A 114ILE A 115ALA A 116TYR A 153LEU A 190 | NAI A4000 (-3.5A)NoneNoneNAI A4000 (-4.8A)NAI A4000 (-3.7A) | 0.47A | 2japB-2dknA:25.6 | 2japB-2dknA:26.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fjc | ANTIGEN TPF1 (Treponemapallidum) |
PF00210(Ferritin) | 5 | LEU A 53ILE A 168ALA A 167TYR A 75LEU A 124 | None | 1.16A | 2japB-2fjcA:undetectable | 2japB-2fjcA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hrz | NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE (Agrobacteriumfabrum) |
PF01370(Epimerase) | 5 | SER A 135ILE A 136ALA A 137TYR A 159THR A 188 | None | 0.79A | 2japB-2hrzA:16.4 | 2japB-2hrzA:24.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2jah | CLAVULANIC ACIDDEHYDROGENASE (Streptomycesclavuligerus) |
PF00106(adh_short) | 7 | MET A 95LEU A 97ALA A 152TYR A 155LEU A 192TYR A 205ARG A 208 | NoneNoneNoneNDP A1248 (-4.7A)NDP A1248 (-3.5A)NoneNone | 1.25A | 2japB-2jahA:46.6 | 2japB-2jahA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2jah | CLAVULANIC ACIDDEHYDROGENASE (Streptomycesclavuligerus) |
PF00106(adh_short) | 11 | MET A 95LEU A 97SER A 142ILE A 143ALA A 144VAL A 149ALA A 152TYR A 155THR A 187LEU A 192TYR A 205 | NoneNoneNDP A1248 (-3.3A)NoneNoneNoneNoneNDP A1248 (-4.7A)NDP A1248 (-4.6A)NDP A1248 (-3.5A)None | 0.15A | 2japB-2jahA:46.6 | 2japB-2jahA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nz2 | ARGININOSUCCINATESYNTHASE (Homo sapiens) |
PF00764(Arginosuc_synth) | 5 | ILE A 38ALA A 36ALA A 10TYR A 34ARG A 95 | None | 1.26A | 2japB-2nz2A:6.2 | 2japB-2nz2A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okc | TYPE I RESTRICTIONENZYME STYSJI MPROTEIN (Bacteroidesthetaiotaomicron) |
PF02384(N6_Mtase)PF12161(HsdM_N) | 5 | LEU A 83ALA A 100TYR A 97LEU A 42TYR A 79 | None | 1.22A | 2japB-2okcA:6.2 | 2japB-2okcA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pef | SERINE PROTEASEINHIBITOR (Caldanaerobactersubterraneus) |
PF00079(Serpin) | 5 | LEU A 92SER A 74ILE A 322ALA A 88LEU A 331 | None | 1.20A | 2japB-2pefA:undetectable | 2japB-2pefA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9l | PUTATIVE DNALIGASE-LIKE PROTEIN (Mycobacteriumtuberculosis) |
no annotation | 5 | MET A 40LEU A 99ILE A 238ALA A 239TYR A 33 | NoneNoneEDO A 295 (-4.1A)NoneNone | 1.18A | 2japB-2r9lA:undetectable | 2japB-2r9lA:25.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v6y | AAA FAMILY ATPASE,P60 KATANIN (Sulfolobussolfataricus) |
PF04212(MIT) | 5 | MET B 60LEU B 41ILE B 16ALA B 15TYR B 64 | None | 1.21A | 2japB-2v6yB:undetectable | 2japB-2v6yB:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w48 | SORBITOL OPERONREGULATOR (Klebsiellapneumoniae) |
PF04198(Sugar-bind)PF13936(HTH_38) | 5 | MET A 95LEU A 92ILE A 291ALA A 120THR A 309 | None | 1.20A | 2japB-2w48A:undetectable | 2japB-2w48A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ww8 | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcuspneumoniae) |
PF13519(VWA_2) | 5 | LEU A 647ILE A 598VAL A 652ALA A 650LEU A 668 | None | 1.24A | 2japB-2ww8A:3.4 | 2japB-2ww8A:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x27 | OUTER MEMBRANEPROTEIN OPRG (Pseudomonasaeruginosa) |
PF03922(OmpW) | 5 | MET X 141LEU X 143VAL X 195ALA X 178LEU X 129 | None | 1.00A | 2japB-2x27X:undetectable | 2japB-2x27X:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x9q | CYCLODIPEPTIDESYNTHETASE (Mycobacteriumtuberculosis) |
PF16715(CDPS) | 5 | ILE A 144ALA A 140TYR A 126THR A 118TYR A 229 | None | 1.13A | 2japB-2x9qA:3.1 | 2japB-2x9qA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdr | BETAINE ALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 5 | SER A 163VAL A 204ALA A 189TYR A 192LEU A 79 | None | 1.17A | 2japB-2xdrA:5.4 | 2japB-2xdrA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zup | DISULFIDE BONDFORMATION PROTEIN B (Escherichiacoli) |
PF02600(DsbB) | 5 | ILE B 63ALA B 14VAL B 161ALA B 157LEU B 55 | None | 1.18A | 2japB-2zupB:undetectable | 2japB-2zupB:24.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bb8 | CDP-4-KETO-6-DEOXY-D-GLUCOSE-3-DEHYDRASE (Yersiniapseudotuberculosis) |
PF01041(DegT_DnrJ_EryC1) | 5 | MET A 204LEU A 75ALA A 195VAL A 214TYR A 74 | None | 1.06A | 2japB-3bb8A:undetectable | 2japB-3bb8A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ez6 | PLASMID PARTITIONPROTEIN A (Escherichiacoli) |
PF13614(AAA_31) | 5 | ILE A 149VAL A 110ALA A 108TYR A 245LEU A 188 | None | 1.11A | 2japB-3ez6A:3.1 | 2japB-3ez6A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htx | HEN1 (Arabidopsisthaliana) |
PF13847(Methyltransf_31) | 5 | LEU A 130VAL A 140ALA A 129LEU A 206TYR A 198 | None | 1.24A | 2japB-3htxA:6.1 | 2japB-3htxA:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hvw | DIGUANYLATE-CYCLASE(DGC) (Pseudomonasaeruginosa) |
PF00990(GGDEF) | 5 | SER A 243ILE A 242VAL A 307ALA A 311LEU A 201 | None | 1.27A | 2japB-3hvwA:undetectable | 2japB-3hvwA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k20 | OXIDOREDUCTASE (Corynebacteriumdiphtheriae) |
PF03358(FMN_red) | 5 | MET A 137LEU A 106ILE A 100ALA A 105LEU A 133 | None | 1.12A | 2japB-3k20A:5.0 | 2japB-3k20A:25.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8k | DIHYDROLIPOYLDEHYDROGENASE (Sulfolobussolfataricus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | MET A 96LEU A 102ALA A 10VAL A 7ALA A 18 | None | 1.25A | 2japB-3l8kA:3.5 | 2japB-3l8kA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk7 | UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATELIGASE (Streptococcusagalactiae) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | LEU A 351ILE A 334ALA A 424VAL A 385ALA A 353 | None | 1.15A | 2japB-3lk7A:2.5 | 2japB-3lk7A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkt | MULTI ANTIMICROBIALEXTRUSION PROTEIN(NA(+)/DRUGANTIPORTER)MATE-LIKE MDR EFFLUXPUMP (Vibrio cholerae) |
PF01554(MatE) | 5 | ILE A 343ALA A 344VAL A 279ALA A 357THR A 336 | None | 1.24A | 2japB-3mktA:undetectable | 2japB-3mktA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwc | SMC PROTEIN (Pyrococcusfuriosus) |
PF06470(SMC_hinge) | 5 | LEU A 575SER A 517ILE A 519VAL A 554LEU A 572 | None | 1.21A | 2japB-3nwcA:undetectable | 2japB-3nwcA:27.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p19 | PUTATIVE BLUEFLUORESCENT PROTEIN (Vibriovulnificus) |
PF00106(adh_short) | 7 | MET A 84LEU A 86SER A 132ALA A 134TYR A 145LEU A 182TYR A 195 | NoneNoneNDP A2001 ( 3.5A)NoneNDP A2001 ( 4.7A)NDP A2001 ( 3.5A)None | 0.46A | 2japB-3p19A:37.2 | 2japB-3p19A:39.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p19 | PUTATIVE BLUEFLUORESCENT PROTEIN (Vibriovulnificus) |
PF00106(adh_short) | 6 | SER A 132ILE A 133ALA A 134TYR A 145LEU A 182TYR A 195 | NDP A2001 ( 3.5A)NoneNoneNDP A2001 ( 4.7A)NDP A2001 ( 3.5A)None | 0.74A | 2japB-3p19A:37.2 | 2japB-3p19A:39.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ppi | 3-HYDROXYACYL-COADEHYDROGENASE TYPE-2 (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | SER A 152ILE A 153ALA A 154TYR A 165THR A 197 | None | 0.86A | 2japB-3ppiA:29.7 | 2japB-3ppiA:27.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r6o | 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATEISOMERASE (Mycobacteroidesabscessus) |
PF01557(FAA_hydrolase) | 5 | ILE A 259VAL A 160ALA A 156THR A 261LEU A 238 | None | 1.12A | 2japB-3r6oA:undetectable | 2japB-3r6oA:23.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tfo | PUTATIVE3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Sinorhizobiummeliloti) |
PF00106(adh_short) | 6 | MET A 92LEU A 94SER A 140ILE A 141ALA A 150TYR A 153 | None | 0.61A | 2japB-3tfoA:34.5 | 2japB-3tfoA:38.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tfo | PUTATIVE3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Sinorhizobiummeliloti) |
PF00106(adh_short) | 6 | MET A 92LEU A 94SER A 140VAL A 147ALA A 150TYR A 153 | None | 0.40A | 2japB-3tfoA:34.5 | 2japB-3tfoA:38.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uf6 | LMO1369 PROTEIN (Listeriamonocytogenes) |
PF01515(PTA_PTB) | 5 | LEU A 129ILE A 230ALA A 167ALA A 226LEU A 240 | None | 1.25A | 2japB-3uf6A:5.3 | 2japB-3uf6A:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usz | EXO-1,3/1,4-BETA-GLUCANASE (Pseudoalteromonassp. BB1) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | ALA A 213VAL A 192ALA A 249TYR A 246LEU A 280 | None | 1.20A | 2japB-3uszA:undetectable | 2japB-3uszA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v57 | PHYCOERYTHRIN BETASUBUNIT (Porphyridiumpurpureum) |
PF00502(Phycobilisome) | 5 | SER B 43ILE B 44ALA B 40VAL B 165ALA B 162 | NoneNonePEB B 204 ( 4.0A)NoneNone | 1.24A | 2japB-3v57B:undetectable | 2japB-3v57B:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v76 | FLAVOPROTEIN (Sinorhizobiummeliloti) |
PF03486(HI0933_like) | 5 | LEU A 258ILE A 254ALA A 218VAL A 229ALA A 216 | None | 1.26A | 2japB-3v76A:2.5 | 2japB-3v76A:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4au2 | SERPIN PEPTIDASEINHIBITOR, CLADE H(HEAT SHOCK PROTEIN47), MEMBER 1,(COLLAGEN BINDINGPROTEIN 1) (Canis lupus) |
PF00079(Serpin) | 5 | LEU A 78ILE A 330ALA A 329ALA A 93LEU A 200 | None | 1.10A | 2japB-4au2A:undetectable | 2japB-4au2A:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c2k | 3-KETOACYL-COATHIOLASE,MITOCHONDRIAL (Homo sapiens) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 304SER A 380ALA A 390ALA A 303LEU A 334 | None | 1.14A | 2japB-4c2kA:undetectable | 2japB-4c2kA:20.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fn4 | SHORT CHAINDEHYDROGENASE (Sulfolobusacidocaldarius) |
PF13561(adh_short_C2) | 5 | LEU A 210SER A 145ILE A 146ALA A 147THR A 190 | NoneNAD A 501 (-3.6A)NoneNoneNone | 0.99A | 2japB-4fn4A:34.3 | 2japB-4fn4A:31.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fn4 | SHORT CHAINDEHYDROGENASE (Sulfolobusacidocaldarius) |
PF13561(adh_short_C2) | 5 | MET A 96SER A 145ILE A 146ALA A 147TYR A 158 | GOL A 502 (-3.5A)NAD A 501 (-3.6A)NoneNoneGOL A 502 ( 4.3A) | 0.79A | 2japB-4fn4A:34.3 | 2japB-4fn4A:31.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fn4 | SHORT CHAINDEHYDROGENASE (Sulfolobusacidocaldarius) |
PF13561(adh_short_C2) | 5 | SER A 145ILE A 146ALA A 147TYR A 158THR A 190 | NAD A 501 (-3.6A)NoneNoneGOL A 502 ( 4.3A)None | 0.62A | 2japB-4fn4A:34.3 | 2japB-4fn4A:31.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hz4 | GLUTATHIONE-S-TRANSFERASE (Actinobacilluspleuropneumoniae) |
PF00043(GST_C)PF02798(GST_N) | 5 | SER A 163VAL A 18ALA A 197TYR A 194LEU A 207 | None | 1.25A | 2japB-4hz4A:undetectable | 2japB-4hz4A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ilr | CRISPR-ASSOCIATEDENDORIBONUCLEASECAS6 2 (Sulfolobussolfataricus) |
PF10040(CRISPR_Cas6) | 5 | LEU A 264ILE A 119ALA A 86TYR A 263LEU A 125 | None | 1.15A | 2japB-4ilrA:undetectable | 2japB-4ilrA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kem | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Azospirillumlipoferum) |
PF13378(MR_MLE_C) | 5 | LEU A 252ILE A 184ALA A 213ALA A 222TYR A 256 | None | 1.19A | 2japB-4kemA:2.8 | 2japB-4kemA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mpt | PUTATIVELEU/ILE/VAL-BINDINGPROTEIN (Bordetellapertussis) |
PF13458(Peripla_BP_6) | 5 | SER A 234VAL A 163TYR A 158LEU A 211TYR A 184 | NoneNoneACY A 401 (-3.4A)NoneNone | 1.17A | 2japB-4mptA:3.1 | 2japB-4mptA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk1 | RIBOSETRANSCRIPTIONALREGULATOR (Enterococcusfaecium) |
PF13377(Peripla_BP_3) | 5 | LEU A 258SER A 242ILE A 221ALA A 244TYR A 273 | None | 1.26A | 2japB-4rk1A:7.5 | 2japB-4rk1A:21.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4tkm | NADH-DEPENDENTREDUCTASE FOR4-DEOXY-L-ERYTHRO-5-HEXOSEULOSE URONATE (Sphingomonassp. A1) |
PF13561(adh_short_C2) | 6 | LEU A 96ILE A 151ALA A 152ALA A 161TYR A 164THR A 196 | None | 1.06A | 2japB-4tkmA:29.8 | 2japB-4tkmA:33.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4tkm | NADH-DEPENDENTREDUCTASE FOR4-DEOXY-L-ERYTHRO-5-HEXOSEULOSE URONATE (Sphingomonassp. A1) |
PF13561(adh_short_C2) | 6 | SER A 150ILE A 151ALA A 152ALA A 161TYR A 164THR A 196 | None | 0.59A | 2japB-4tkmA:29.8 | 2japB-4tkmA:33.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4e | THIOLASE (Sphaerobacterthermophilus) |
PF02803(Thiolase_C) | 5 | LEU A 39ILE A 104ALA A 213ALA A 38LEU A 66 | None | 1.03A | 2japB-4u4eA:undetectable | 2japB-4u4eA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v16 | SVP1-LIKE PROTEIN 2 (Kluyveromyceslactis) |
no annotation | 5 | LEU A 45ILE A 17VAL A 306ALA A 313TYR A 40 | None | 1.21A | 2japB-4v16A:undetectable | 2japB-4v16A:20.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w7h | CARBONYL REDUCTASE (Sphingomonassp. A1) |
PF13561(adh_short_C2) | 6 | LEU A 96ILE A 151ALA A 152ALA A 161TYR A 164THR A 196 | None | 1.27A | 2japB-4w7hA:30.1 | 2japB-4w7hA:33.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w7h | CARBONYL REDUCTASE (Sphingomonassp. A1) |
PF13561(adh_short_C2) | 6 | SER A 150ILE A 151ALA A 152ALA A 161TYR A 164THR A 196 | None | 0.96A | 2japB-4w7hA:30.1 | 2japB-4w7hA:33.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w7h | CARBONYL REDUCTASE (Sphingomonassp. A1) |
PF13561(adh_short_C2) | 5 | SER A 150ILE A 151ALA A 152THR A 196LEU A 96 | None | 1.20A | 2japB-4w7hA:30.1 | 2japB-4w7hA:33.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w91 | AMINOTRANSFERASE (Brucella suis) |
PF00266(Aminotran_5) | 5 | ILE A 241ALA A 291VAL A 84TYR A 77THR A 99 | None | 0.92A | 2japB-4w91A:2.8 | 2japB-4w91A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yqz | PUTATIVEOXIDOREDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 5 | SER A 127ALA A 129VAL A 134TYR A 140THR A 172 | None | 0.56A | 2japB-4yqzA:30.0 | 2japB-4yqzA:29.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfh | ARTIFICIAL ANKYRINREPEATPROTEIN_ANK(GAG)1D4MUTANT -Y56A (Homo sapiens) |
PF12796(Ank_2)PF13857(Ank_5) | 5 | LEU A 133SER A 153ILE A 152ALA A 121THR A 148 | None | 1.24A | 2japB-4zfhA:undetectable | 2japB-4zfhA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a55 | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Streptococcuspneumoniae) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | SER A 771ILE A 733ALA A 735TYR A 664ARG A 746 | None | 1.21A | 2japB-5a55A:undetectable | 2japB-5a55A:12.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6d | DNA POLYMERASESLIDING CLAMP (Thermococcusgammatolerans) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | LEU A 243SER A 44ALA A 244LEU A 23ARG A 246 | None | 1.23A | 2japB-5a6dA:undetectable | 2japB-5a6dA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7s | CYSTEINE DESULFURASE (Thermococcusonnurineus) |
PF00266(Aminotran_5) | 5 | ILE A 224ALA A 274VAL A 69TYR A 62THR A 83 | None | 0.86A | 2japB-5b7sA:3.1 | 2japB-5b7sA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czz | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Staphylococcusaureus) |
PF13395(HNH_4)PF16592(Cas9_REC) | 5 | LEU A 395ILE A 417ALA A 399TYR A 239TYR A 256 | A B 4 ( 4.6A)NoneNone A B 3 ( 4.8A) A B 4 ( 4.4A) | 1.22A | 2japB-5czzA:3.0 | 2japB-5czzA:11.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6s | EPOXYQUEUOSINEREDUCTASE (Streptococcusthermophilus) |
PF08331(DUF1730)PF13484(Fer4_16) | 5 | LEU A 268ILE A 298ALA A 299THR A 327LEU A 312 | None | 1.06A | 2japB-5d6sA:undetectable | 2japB-5d6sA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e8k | GERANYLGERANYLPYROPHOSPHATESYNTHASE 10,MITOCHONDRIAL (Arabidopsisthaliana) |
PF00348(polyprenyl_synt) | 5 | ILE A 300ALA A 297ALA A 278TYR A 219LEU A 58 | None | 1.25A | 2japB-5e8kA:undetectable | 2japB-5e8kA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h53 | SKELETAL MUSCLEMYOSIN HEAVY CHAINMYHC-EO/IIL (Oryctolaguscuniculus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 5 | MET A 390LEU A 618ALA A 357VAL A 433TYR A 611 | None | 1.02A | 2japB-5h53A:undetectable | 2japB-5h53A:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iq6 | RNA DEPENDENT RNAPOLYMERASE (Dengue virus) |
PF00972(Flavi_NS5) | 5 | ALA A 866VAL A 870ALA A 782THR A 328LEU A 774 | None | 1.15A | 2japB-5iq6A:undetectable | 2japB-5iq6A:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j49 | UTP--GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Paraburkholderiaxenovorans) |
PF00483(NTP_transferase) | 5 | LEU A 210ILE A 189VAL A 244TYR A 208LEU A 111 | None | 0.93A | 2japB-5j49A:2.9 | 2japB-5j49A:24.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5m | RNA DEPENDENT RNAPOLYMERASE (Dengue virus) |
PF00972(Flavi_NS5) | 5 | ALA A 866VAL A 870ALA A 782THR A 329LEU A 774 | None | 1.15A | 2japB-5k5mA:undetectable | 2japB-5k5mA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks1 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Vibriovulnificus) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | LEU A 7ALA A 32VAL A 55ALA A 34THR A 90 | None | 1.12A | 2japB-5ks1A:9.0 | 2japB-5ks1A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l0j | VINCULIN (Homo sapiens) |
PF01044(Vinculin) | 5 | MET A 926ILE A 919ALA A 957THR A1037LEU A 905 | None | 1.24A | 2japB-5l0jA:undetectable | 2japB-5l0jA:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ln1 | 26S PROTEASOMEREGULATORY SUBUNITRPN10 (Saccharomycescerevisiae) |
PF13519(VWA_2) | 5 | ILE A 93ALA A 94ALA A 112THR A 89LEU A 128 | None | 1.15A | 2japB-5ln1A:5.5 | 2japB-5ln1A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lq3 | CMEB (Campylobacterjejuni) |
PF00873(ACR_tran) | 5 | LEU A 400ILE A 483VAL A 407ALA A 403LEU A 385 | None | 1.04A | 2japB-5lq3A:undetectable | 2japB-5lq3A:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkf | POLYCYSTIN-2 (Homo sapiens) |
PF08016(PKD_channel) | 5 | LEU A 415ILE A 424VAL A 443THR A 283LEU A 409 | None | 1.18A | 2japB-5mkfA:undetectable | 2japB-5mkfA:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sy1 | STRA6 (Danio rerio) |
PF14752(RBP_receptor) | 5 | LEU A 138ILE A 44TYR A 135THR A 159LEU A 193 | None | 1.03A | 2japB-5sy1A:undetectable | 2japB-5sy1A:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5txk | UBIQUITINCARBOXYL-TERMINALHYDROLASE35,UBIQUITINCARBOXYL-TERMINALHYDROLASE 35 (Homo sapiens) |
no annotation | 5 | LEU A 774SER A 587ALA A 791TYR A 780THR A 576 | None | 1.10A | 2japB-5txkA:undetectable | 2japB-5txkA:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ver | KYNURENINE--OXOGLUTARATE TRANSAMINASE 3 (Mus musculus) |
no annotation | 5 | LEU A 139VAL A 249ALA A 135TYR A 136TYR A 163 | NoneNonePLP A 701 (-3.4A)PLP A 701 (-4.7A)None | 1.22A | 2japB-5verA:3.4 | 2japB-5verA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wi9 | - (-) |
no annotation | 5 | LEU A 141SER A 130ALA A 140LEU A 178TYR A 149 | None | 1.17A | 2japB-5wi9A:2.6 | 2japB-5wi9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wix | P-47 PROTEIN (Clostridiumbotulinum) |
no annotation | 5 | LEU A 191SER A 163ILE A 165LEU A 159TYR A 10 | None | 1.24A | 2japB-5wixA:undetectable | 2japB-5wixA:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnp | LEUCINE-RICH REPEATAND FIBRONECTINTYPE-IIIDOMAIN-CONTAININGPROTEIN 5RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE DELTA (Homo sapiens) |
no annotation | 5 | MET D 130LEU D 146ILE A 318ALA A 317LEU A 327 | None | 1.01A | 2japB-5xnpD:undetectable | 2japB-5xnpD:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyh | CBSA (Xanthomonasoryzae) |
no annotation | 5 | SER A 200ILE A 202ALA A 197ALA A 193THR A 144 | None | 1.26A | 2japB-5xyhA:undetectable | 2japB-5xyhA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f6e | RIBONUCLEOTIDEREDUCTASE SMALLSUBUNIT (Geobacilluskaustophilus) |
no annotation | 5 | MET A 79LEU A 146ILE A 213ALA A 159LEU A 83 | None | 1.25A | 2japB-6f6eA:undetectable | 2japB-6f6eA:12.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gne | - (-) |
no annotation | 5 | LEU A 144SER A 182ALA A 183VAL A 28TYR A 171 | None | 1.23A | 2japB-6gneA:7.2 | 2japB-6gneA:undetectable |