SIMILAR PATTERNS OF AMINO ACIDS FOR 2J5M_A_ACTA1321

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2o CHEB METHYLESTERASE

(Salmonella
enterica) 		PF00072
(Response_reg)
PF01339
(CheB_methylest) 		4 LEU A 175
PHE A 199
ILE A 227
ALA A 225
 None
 1.08A 2j5mA-1a2oA:
0.0		 2j5mA-1a2oA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chd CHEB METHYLESTERASE

(Salmonella
enterica) 		PF01339
(CheB_methylest) 		4 LEU A 175
PHE A 199
ILE A 227
ALA A 225
 None
 1.01A 2j5mA-1chdA:
0.0		 2j5mA-1chdA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dp2 RHODANESE

(Bos taurus) 		PF00581
(Rhodanese) 		4 LEU A 239
ILE A 256
VAL A 268
ALA A 260
 None
 0.82A 2j5mA-1dp2A:
0.0		 2j5mA-1dp2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i0a DELTA CRYSTALLIN I

(Meleagris
gallopavo) 		PF00206
(Lyase_1)
PF14698
(ASL_C2) 		4 LEU A 339
ILE A 243
VAL A 303
ALA A 246
 None
 1.06A 2j5mA-1i0aA:
0.0		 2j5mA-1i0aA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idm 3-ISOPROPYLMALATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 LEU A  23
ILE A 289
VAL A 309
ALA A 292
 None
 0.91A 2j5mA-1idmA:
0.0		 2j5mA-1idmA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nkp MYC PROTO-ONCOGENE
PROTEIN
MAX PROTEIN

(Homo sapiens;
Homo sapiens) 		PF00010
(HLH)
PF02344
(Myc-LZ)
PF00010
(HLH) 		4 LEU A 924
PHE B 222
ILE B 242
ALA B 246
 None
 0.91A 2j5mA-1nkpA:
undetectable		 2j5mA-1nkpA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nkp MYC PROTO-ONCOGENE
PROTEIN
MAX PROTEIN

(Homo sapiens;
Homo sapiens) 		PF00010
(HLH)
PF02344
(Myc-LZ)
PF00010
(HLH) 		4 LEU B 225
PHE A 921
ILE A 942
ALA A 946
 None
 0.90A 2j5mA-1nkpB:
undetectable		 2j5mA-1nkpB:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uxt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(NADP+)

(Thermoproteus
tenax) 		PF00171
(Aldedh) 		4 LEU A 409
ILE A 435
VAL A 427
ALA A 438
 None
 0.93A 2j5mA-1uxtA:
0.0		 2j5mA-1uxtA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wac P2 PROTEIN

(Pseudomonas
virus phi6) 		PF00680
(RdRP_1) 		4 LEU A 400
PHE A 357
ILE A 283
ALA A 287
 None
 1.09A 2j5mA-1wacA:
0.0		 2j5mA-1wacA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0l HOMOISOCITRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 LEU A  25
ILE A 278
VAL A 297
ALA A 281
 None
 0.91A 2j5mA-1x0lA:
undetectable		 2j5mA-1x0lA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zr5 H2AFY PROTEIN

(Homo sapiens) 		PF01661
(Macro) 		4 LEU A 205
PHE A 181
VAL A 210
ALA A 308
 None
 0.99A 2j5mA-1zr5A:
0.0		 2j5mA-1zr5A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvu TOPOISOMERASE IV
SUBUNIT A

(Escherichia
coli) 		PF00521
(DNA_topoisoIV)
PF03989
(DNA_gyraseA_C) 		4 LEU A 420
ILE A 386
VAL A 389
ALA A 382
 None
 0.81A 2j5mA-1zvuA:
undetectable		 2j5mA-1zvuA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmb FOLIC ACID SYNTHESIS
PROTEIN FOL1

(Saccharomyces
cerevisiae) 		PF00809
(Pterin_bind)
PF01288
(HPPK) 		4 LEU A 577
ILE A 546
VAL A 588
ALA A 548
 None
 0.90A 2j5mA-2bmbA:
undetectable		 2j5mA-2bmbA:
18.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ciy CHLOROPEROXIDASE

(Leptoxyphium
fumago) 		PF01328
(Peroxidase_2) 		6 LEU A  70
ASN A  74
PHE A 103
ILE A 179
VAL A 182
ALA A 267
 DMS  A3036 (-3.9A)
DMS  A3036 (-3.9A)
DMS  A3036 (-3.8A)
DMS  A3036 (-4.8A)
MAN  A 741 ( 4.3A)
EDO  A 802 (-4.1A)
 0.18A 2j5mA-2ciyA:
53.4		 2j5mA-2ciyA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2db3 ATP-DEPENDENT RNA
HELICASE VASA

(Drosophila
melanogaster) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 LEU A 300
ILE A 373
VAL A 371
ALA A 338
 None
 0.86A 2j5mA-2db3A:
undetectable		 2j5mA-2db3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE

(Candida
albicans) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 LEU A 359
ILE A 339
VAL A 341
ALA A 320
 None
 0.94A 2j5mA-2dkdA:
undetectable		 2j5mA-2dkdA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpl GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG] SUBUNIT B

(Pyrococcus
horikoshii) 		PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		4 LEU A  48
ILE A 158
VAL A  18
ALA A  23
 None
 1.03A 2j5mA-2dplA:
undetectable		 2j5mA-2dplA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drh 361AA LONG
HYPOTHETICAL
D-AMINOPEPTIDASE

(Pyrococcus
horikoshii) 		PF03576
(Peptidase_S58) 		4 ASN A 100
ILE A 104
VAL A 133
ALA A 107
 None
 0.97A 2j5mA-2drhA:
undetectable		 2j5mA-2drhA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9n EUKARYOTIC
INITIATION FACTOR
4A-I

(Homo sapiens) 		PF00270
(DEAD) 		4 LEU A 211
PHE A 200
ILE A 196
ALA A 184
 None
None
MLY  A 193 ( 4.1A)
None
 1.06A 2j5mA-2g9nA:
undetectable		 2j5mA-2g9nA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gk4 CONSERVED
HYPOTHETICAL PROTEIN

(Streptococcus
pneumoniae) 		PF04127
(DFP) 		4 LEU A 168
ILE A 184
VAL A 202
ALA A 186
 None
 1.08A 2j5mA-2gk4A:
undetectable		 2j5mA-2gk4A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lm3 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5

(Macaca mulatta) 		PF00622
(SPRY) 		4 ASN A 308
ILE A 315
VAL A 322
ALA A 313
 None
 0.99A 2j5mA-2lm3A:
undetectable		 2j5mA-2lm3A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oi8 PUTATIVE REGULATORY
PROTEIN SCO4313

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		4 LEU A  67
PHE A  57
ILE A  21
ALA A  25
 None
 1.04A 2j5mA-2oi8A:
undetectable		 2j5mA-2oi8A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1

(Homo sapiens) 		PF02580
(Tyr_Deacylase) 		4 LEU A  75
ILE A 135
VAL A   8
ALA A  11
 None
 0.78A 2j5mA-2okvA:
undetectable		 2j5mA-2okvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqh PUTATIVE ISOMERASE

(Streptomyces
coelicolor) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 338
ILE A 304
VAL A 355
ALA A 307
 None
 1.07A 2j5mA-2oqhA:
undetectable		 2j5mA-2oqhA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3v INOSITOL-1-MONOPHOSP
HATASE

(Thermotoga
maritima) 		PF00459
(Inositol_P) 		4 LEU A1017
PHE A1087
ILE A1081
ALA A1045
 None
 1.09A 2j5mA-2p3vA:
undetectable		 2j5mA-2p3vA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ql2 TRANSCRIPTION FACTOR
E2-ALPHA
NEUROGENIC
DIFFERENTIATION
FACTOR 1

(Mus musculus;
Mus musculus) 		PF00010
(HLH)
PF00010
(HLH) 		4 LEU B 124
PHE A 562
ILE A 584
ALA A 588
 None
 0.84A 2j5mA-2ql2B:
undetectable		 2j5mA-2ql2B:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rkv TRICHOTHECENE
3-O-ACETYLTRANSFERAS
E

(Fusarium
graminearum) 		PF02458
(Transferase) 		4 LEU A 429
ILE A 269
VAL A 375
ALA A 273
 None
 1.02A 2j5mA-2rkvA:
undetectable		 2j5mA-2rkvA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9j SIGNAL RECOGNITION
PARTICLE SUBUNIT
SRP14

(Schizosaccharomyces
pombe) 		PF02290
(SRP14) 		4 LEU A  12
PHE A  70
ILE A  48
ALA A  50
 None
None
CAS  A  33 ( 4.1A)
None
 0.85A 2j5mA-2w9jA:
undetectable		 2j5mA-2w9jA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wc7 ALPHA AMYLASE,
CATALYTIC REGION

(Nostoc
punctiforme) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		4 LEU A 200
PHE A 224
ILE A 237
ALA A 235
 None
 0.94A 2j5mA-2wc7A:
undetectable		 2j5mA-2wc7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dlj BETA-ALA-HIS
DIPEPTIDASE

(Homo sapiens) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 PHE A  23
ILE A  16
VAL A  12
ALA A 471
 None
 1.02A 2j5mA-3dljA:
undetectable		 2j5mA-3dljA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5b ISOCITRATE LYASE

(Brucella
abortus) 		PF00463
(ICL) 		4 ASN A 118
ILE A  81
VAL A  74
ALA A 142
 None
 0.89A 2j5mA-3e5bA:
undetectable		 2j5mA-3e5bA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gfk REGULATORY PROTEIN
SPX

(Bacillus
subtilis) 		PF03960
(ArsC) 		4 LEU A   4
PHE A 113
ILE A 110
ALA A  16
 None
 0.90A 2j5mA-3gfkA:
undetectable		 2j5mA-3gfkA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2t BASEPLATE STRUCTURAL
PROTEIN GP6

(Escherichia
virus T4) 		no annotation 4 LEU A 465
PHE A 459
ILE A 482
ALA A 480
 None
 1.08A 2j5mA-3h2tA:
undetectable		 2j5mA-3h2tA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4e ISOCITRATE LYASE

(Burkholderia
pseudomallei) 		PF00463
(ICL) 		4 ASN A 122
ILE A  85
VAL A  78
ALA A 149
 None
 0.92A 2j5mA-3i4eA:
undetectable		 2j5mA-3i4eA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3inp D-RIBULOSE-PHOSPHATE
3-EPIMERASE

(Francisella
tularensis) 		PF00834
(Ribul_P_3_epim) 		4 LEU A 174
PHE A 196
ILE A 188
ALA A 158
 None
 0.91A 2j5mA-3inpA:
undetectable		 2j5mA-3inpA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyd SUMO-ACTIVATING
ENZYME SUBUNIT 2

(Homo sapiens) 		PF00899
(ThiF)
PF14732
(UAE_UbL) 		4 LEU B  81
ILE B  44
VAL B  37
ALA B  87
 None
 0.94A 2j5mA-3kydB:
undetectable		 2j5mA-3kydB:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l78 REGULATORY PROTEIN
SPX

(Streptococcus
mutans) 		PF03960
(ArsC) 		4 LEU A   4
PHE A 113
ILE A 110
ALA A  16
 None
 0.97A 2j5mA-3l78A:
undetectable		 2j5mA-3l78A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lp8 PHOSPHORIBOSYLAMINE-
GLYCINE LIGASE

(Ehrlichia
chaffeensis) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 LEU A 357
ASN A 359
VAL A 384
ALA A 401
 None
 0.85A 2j5mA-3lp8A:
undetectable		 2j5mA-3lp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6i L-ARABINITOL
4-DEHYDROGENASE

(Neurospora
crassa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 172
ILE A 185
VAL A 183
ALA A 199
 None
 0.70A 2j5mA-3m6iA:
undetectable		 2j5mA-3m6iA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5

(Saccharomyces
cerevisiae) 		PF00397
(WW)
PF00632
(HECT) 		4 LEU A 507
ILE A 457
VAL A 459
ALA A 468
 None
 0.91A 2j5mA-3olmA:
undetectable		 2j5mA-3olmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0s CAPSID PROTEIN VP

(Lepidopteran
iteradensovirus
1) 		PF01057
(Parvo_NS1) 		4 LEU A 436
ASN A 341
ILE A 184
VAL A 180
 None
 0.96A 2j5mA-3p0sA:
undetectable		 2j5mA-3p0sA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pyw S-LAYER PROTEIN SAP

(Bacillus
anthracis) 		PF00395
(SLH) 		4 PHE A  66
ILE A  78
VAL A  81
ALA A  47
 None
 0.93A 2j5mA-3pywA:
undetectable		 2j5mA-3pywA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rh0 ARSENATE REDUCTASE

(Corynebacterium
glutamicum) 		PF01451
(LMWPc) 		4 PHE A   6
ILE A  32
VAL A  30
ALA A  26
 None
 0.97A 2j5mA-3rh0A:
undetectable		 2j5mA-3rh0A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7b ACETYLGLUTAMATE
KINASE

(Yersinia pestis) 		PF00696
(AA_kinase) 		4 LEU A 221
ASN A 218
ILE A 209
ALA A 200
 None
 1.01A 2j5mA-3t7bA:
undetectable		 2j5mA-3t7bA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9r METHYLCROTONYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa) 		PF01039
(Carboxyl_trans) 		4 LEU B  90
ILE B 209
VAL B 211
ALA B 287
 None
 0.95A 2j5mA-3u9rB:
undetectable		 2j5mA-3u9rB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uv9 TRIPARTITE
MOTIF-CONTAINING
PROTEIN 5

(Macaca mulatta) 		PF00622
(SPRY) 		4 ASN A 308
ILE A 315
VAL A 322
ALA A 313
 None
 0.98A 2j5mA-3uv9A:
undetectable		 2j5mA-3uv9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8d CHOLESTEROL
7-ALPHA-MONOOXYGENAS
E

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 361
PHE A 100
ILE A 386
ALA A 388
 None
 1.09A 2j5mA-3v8dA:
undetectable		 2j5mA-3v8dA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vdr D-3-HYDROXYBUTYRATE
DEHYDROGENASE

(Alcaligenes
faecalis) 		PF00106
(adh_short) 		4 LEU A  60
ILE A  74
VAL A   8
ALA A  77
 None
 0.98A 2j5mA-3vdrA:
undetectable		 2j5mA-3vdrA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr5 V-TYPE SODIUM ATPASE
CATALYTIC SUBUNIT A
V-TYPE SODIUM ATPASE
SUBUNIT B

(Enterococcus
hirae;
Enterococcus
hirae) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 LEU A  91
ASN D 117
VAL A 270
ALA A 293
 None
 1.07A 2j5mA-3vr5A:
undetectable		 2j5mA-3vr5A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		4 LEU A  86
ILE A  21
VAL A  31
ALA A  24
 None
 0.87A 2j5mA-3x1jA:
undetectable		 2j5mA-3x1jA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zh4 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Streptococcus
pneumoniae) 		PF00275
(EPSP_synthase) 		4 LEU A 314
PHE A 264
ILE A 241
ALA A 245
 None
 0.92A 2j5mA-3zh4A:
undetectable		 2j5mA-3zh4A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bem F1FO ATPASE C1
SUBUNIT

(Acetobacterium
woodii) 		PF00137
(ATP-synt_C) 		4 LEU J  92
ASN J  96
ILE J  24
ALA J 112
 None
 0.95A 2j5mA-4bemJ:
undetectable		 2j5mA-4bemJ:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bem F1FO ATPASE C2
SUBUNIT

(Acetobacterium
woodii) 		PF00137
(ATP-synt_C) 		4 LEU A  75
ASN A  79
PHE A  82
ILE A   7
 None
 0.96A 2j5mA-4bemA:
undetectable		 2j5mA-4bemA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bem F1FO ATPASE C2
SUBUNIT
F1FO ATPASE C1
SUBUNIT

(Acetobacterium
woodii;
Acetobacterium
woodii) 		PF00137
(ATP-synt_C)
PF00137
(ATP-synt_C) 		4 LEU J 175
ASN J 179
ILE J 107
ALA A  12
 None
 0.87A 2j5mA-4bemJ:
undetectable		 2j5mA-4bemJ:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bpc RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE S

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 LEU A1897
ILE A1908
VAL A1906
ALA A1936
 None
 0.96A 2j5mA-4bpcA:
undetectable		 2j5mA-4bpcA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2i LARGE T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF06431
(Polyoma_lg_T_C) 		4 LEU A 288
PHE A 327
ILE A 336
ALA A 340
 None
 0.93A 2j5mA-4e2iA:
undetectable		 2j5mA-4e2iA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ehi BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH

(Campylobacter
jejuni) 		PF01808
(AICARFT_IMPCHas)
PF02142
(MGS) 		4 LEU A 350
PHE A 231
ILE A 246
ALA A 300
 None
 0.71A 2j5mA-4ehiA:
undetectable		 2j5mA-4ehiA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fkm SIMILAR TO FERRIC
HYDROXAMATE RECEPTOR
1

(Staphylococcus
aureus) 		PF01497
(Peripla_BP_2) 		4 LEU A  81
ILE A  68
VAL A  71
ALA A  58
 MLY  A  82 ( 4.3A)
None
MLY  A  90 ( 4.8A)
None
 1.02A 2j5mA-4fkmA:
undetectable		 2j5mA-4fkmA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdf LARGE T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF02217
(T_Ag_DNA_bind)
PF06431
(Polyoma_lg_T_C) 		4 LEU A 288
PHE A 327
ILE A 336
ALA A 340
 None
 0.79A 2j5mA-4gdfA:
undetectable		 2j5mA-4gdfA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4im4 ENDOGLUCANASE E

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase) 		4 LEU A 137
PHE A 179
ILE A 145
ALA A 143
 None
 0.92A 2j5mA-4im4A:
undetectable		 2j5mA-4im4A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imd N-ACETYLNEURAMINATE
LYASE

(Pasteurella
multocida) 		PF00701
(DHDPS) 		4 LEU A  76
ILE A  34
VAL A  30
ALA A  70
 None
 1.06A 2j5mA-4imdA:
undetectable		 2j5mA-4imdA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4izg MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
N-TERMINAL DOMAIN
PROTEIN

(Paracoccus
denitrificans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 161
ILE A 146
VAL A 180
ALA A 150
 None
 0.80A 2j5mA-4izgA:
undetectable		 2j5mA-4izgA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o1r REPLICATIVE DNA
HELICASE

(Nostoc
punctiforme) 		PF14890
(Intein_splicing) 		4 LEU A   2
PHE A  75
ILE A 135
ALA A 132
 None
 1.09A 2j5mA-4o1rA:
undetectable		 2j5mA-4o1rA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9u NAD(P)
TRANSHYDROGENASE
SUBUNIT BETA

(Thermus
thermophilus) 		PF02233
(PNTB) 		4 LEU B 397
ASN B 362
VAL B 296
ALA B 329
 None
 1.09A 2j5mA-4o9uB:
undetectable		 2j5mA-4o9uB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rs7 PARB-C

(Sulfolobus sp.
NOB8H2) 		no annotation 4 LEU R 377
ILE R 387
VAL R 391
ALA R 401
 None
 0.90A 2j5mA-4rs7R:
undetectable		 2j5mA-4rs7R:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry8 PERIPLASMIC BINDING
PROTEIN

(Pseudothermotoga
lettingae) 		PF13407
(Peripla_BP_4) 		4 LEU A 294
ILE A 133
VAL A 119
ALA A 284
 None
 1.02A 2j5mA-4ry8A:
undetectable		 2j5mA-4ry8A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7t DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A

(Homo sapiens) 		PF00145
(DNA_methylase) 		4 LEU A 639
PHE A 701
ILE A 695
VAL A 690
 None
 1.02A 2j5mA-4u7tA:
undetectable		 2j5mA-4u7tA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yba REGULATORY PROTEIN C

(Klebsiella
pneumoniae) 		PF01381
(HTH_3) 		4 LEU A  20
PHE A  68
ILE A  13
ALA A  16
 LEU  A  20 ( 0.6A)
PHE  A  68 ( 1.3A)
ILE  A  13 ( 0.7A)
ALA  A  16 ( 0.0A)
 1.01A 2j5mA-4ybaA:
undetectable		 2j5mA-4ybaA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yco TRNA-DIHYDROURIDINE
SYNTHASE C

(Escherichia
coli) 		PF01207
(Dus) 		4 LEU A  20
ASN A  24
ILE A 223
ALA A 227
 None
 1.06A 2j5mA-4ycoA:
undetectable		 2j5mA-4ycoA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhb IRON-CHELATOR
UTILIZATION PROTEIN

(Thermobifida
fusca) 		PF04954
(SIP)
PF08021
(FAD_binding_9) 		4 PHE A 172
ILE A 191
VAL A 168
ALA A 185
 None
 0.77A 2j5mA-4yhbA:
undetectable		 2j5mA-4yhbA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysl BETA-LACTAMASE
DOMAIN PROTEIN

(Pseudomonas
putida) 		PF00753
(Lactamase_B) 		4 PHE A 124
ILE A 100
VAL A 103
ALA A 152
 None
 1.01A 2j5mA-4yslA:
undetectable		 2j5mA-4yslA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmh UNCHARACTERIZED
PROTEIN

(Saccharophagus
degradans) 		PF15979
(Glyco_hydro_115) 		4 LEU A 124
ILE A 129
VAL A 109
ALA A 155
 None
 1.04A 2j5mA-4zmhA:
undetectable		 2j5mA-4zmhA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b64 PROTEIN KIF13B

(Mus musculus) 		PF12423
(KIF1B) 		4 LEU B 753
ILE B 690
VAL B 715
ALA B 693
 None
 0.98A 2j5mA-5b64B:
undetectable		 2j5mA-5b64B:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cbk SHHTL5

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 LEU A 198
ILE A 106
VAL A 205
ALA A 102
 None
 1.09A 2j5mA-5cbkA:
undetectable		 2j5mA-5cbkA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5doi TELOMERASE
ASSOCIATED PROTEIN
P45

(Tetrahymena
thermophila) 		no annotation 4 LEU E  63
PHE E  24
ILE E  52
ALA E  50
 None
 0.99A 2j5mA-5doiE:
undetectable		 2j5mA-5doiE:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2e BETA-LACTAMASE

(Yersinia
enterocolitica) 		PF13354
(Beta-lactamase2) 		4 PHE A  51
ILE A 223
VAL A 235
ALA A 164
 None
 0.95A 2j5mA-5e2eA:
undetectable		 2j5mA-5e2eA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eix DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A

(Klebsiella
pneumoniae) 		PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim) 		4 LEU A1420
ILE A1386
VAL A1389
ALA A1382
 None
 0.93A 2j5mA-5eixA:
undetectable		 2j5mA-5eixA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hg0 PANTOTHENATE
SYNTHETASE

(Francisella
tularensis) 		PF02569
(Pantoate_ligase) 		4 LEU A 182
ASN A 188
ILE A 196
ALA A 199
 None
 1.09A 2j5mA-5hg0A:
undetectable		 2j5mA-5hg0A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpl RSP5

(Saccharomyces
cerevisiae) 		PF00632
(HECT) 		4 LEU A 507
ILE A 457
VAL A 459
ALA A 468
 None
 0.75A 2j5mA-5hplA:
undetectable		 2j5mA-5hplA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j47 LARGE T ANTIGEN

(Human
polyomavirus 2) 		PF06431
(Polyoma_lg_T_C) 		4 LEU A 289
PHE A 328
ILE A 337
ALA A 341
 None
 0.74A 2j5mA-5j47A:
undetectable		 2j5mA-5j47A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0t METHIONINE--TRNA
LIGASE

(Brucella suis) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		4 LEU A 475
ILE A 367
VAL A 375
ALA A 450
 None
 0.98A 2j5mA-5k0tA:
undetectable		 2j5mA-5k0tA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lb3 ATP-DEPENDENT DNA
HELICASE Q5

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		4 LEU B 179
ILE B  74
VAL B  76
ALA B 133
 None
 1.04A 2j5mA-5lb3B:
undetectable		 2j5mA-5lb3B:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mju EXCITATORY AMINO
ACID TRANSPORTER
1,NEUTRAL AMINO ACID
TRANSPORTER
B(0),EXCITATORY
AMINO ACID
TRANSPORTER 1

(Homo sapiens) 		PF00375
(SDF) 		4 PHE A 233
ILE A 105
VAL A 248
ALA A 109
 None
 0.87A 2j5mA-5mjuA:
undetectable		 2j5mA-5mjuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC

(Oryza sativa) 		PF01593
(Amino_oxidase) 		4 LEU A 132
ILE A 325
VAL A 329
ALA A 120
 None
 0.89A 2j5mA-5mogA:
undetectable		 2j5mA-5mogA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3o RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE

(Thermus
thermophilus) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		4 LEU A  49
ILE A  56
VAL A  86
ALA A  78
 None
 1.08A 2j5mA-5t3oA:
undetectable		 2j5mA-5t3oA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tgd FOLM ALTERNATIVE
DIHYDROFOLATE
REDUCTASE

(Brucella suis) 		PF00106
(adh_short) 		4 LEU A 182
ILE A 190
VAL A 150
ALA A 135
 None
 1.09A 2j5mA-5tgdA:
undetectable		 2j5mA-5tgdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tii 3-OXOACYL-ACP
REDUCTASE

(uncultured
bacterium) 		PF13561
(adh_short_C2) 		4 LEU A 133
PHE A 182
ILE A 126
ALA A 129
 None
 0.81A 2j5mA-5tiiA:
undetectable		 2j5mA-5tiiA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0l N-SUCCINYLGLUTAMATE
5-SEMIALDEHYDE
DEHYDROGENASE

(Marinobacter
hydrocarbonoclasticus) 		PF00171
(Aldedh) 		4 LEU A 351
PHE A 275
ILE A 310
ALA A 308
 None
 1.08A 2j5mA-5u0lA:
undetectable		 2j5mA-5u0lA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb CELL DIVISION
CONTROL PROTEIN 6

(Saccharomyces
cerevisiae) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		4 LEU 9 334
ILE 9 317
VAL 9 300
ALA 9 321
 None
 0.85A 2j5mA-5udb9:
undetectable		 2j5mA-5udb9:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5unc PHOSPHOENOLPYRUVATE
PHOSPHOMUTASE

(Streptomyces
platensis) 		PF13714
(PEP_mutase) 		4 PHE A 150
ILE A 154
VAL A 168
ALA A 157
 None
 0.86A 2j5mA-5uncA:
undetectable		 2j5mA-5uncA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vha DEAH
(ASP-GLU-ALA-HIS)
BOX POLYPEPTIDE 36

(Bos taurus) 		no annotation 4 PHE A 883
ILE A 848
VAL A 861
ALA A 846
 None
 0.94A 2j5mA-5vhaA:
undetectable		 2j5mA-5vhaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vu2 E1 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		no annotation 4 LEU M  33
ASN M   9
VAL M 163
ALA M 131
 None
 0.98A 2j5mA-5vu2M:
undetectable		 2j5mA-5vu2M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnd PARVALBUMIN BETA

(Scomber
japonicus) 		no annotation 4 LEU A  36
PHE A  67
ILE A  51
ALA A  47
 None
 1.06A 2j5mA-5xndA:
undetectable		 2j5mA-5xndA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqo PCRGLX PROTEIN

(Penicillium
chrysogenum) 		no annotation 4 LEU A 278
ILE A 288
VAL A 302
ALA A 414
 None
 0.97A 2j5mA-5xqoA:
undetectable		 2j5mA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
ES24

(Toxoplasma
gondii) 		PF01282
(Ribosomal_S24e) 		4 PHE Y  50
ILE Y  46
VAL Y  27
ALA Y  76
 U  2 778 ( 4.2A)
None
None
None
 1.09A 2j5mA-5xxuY:
undetectable		 2j5mA-5xxuY:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r X-RAY REPAIR
CROSS-COMPLEMENTING
PROTEIN 6

(Homo sapiens) 		PF02735
(Ku)
PF03730
(Ku_C)
PF03731
(Ku_N) 		4 LEU A 239
PHE A 169
ILE A  67
VAL A  70
 None
 1.09A 2j5mA-5y3rA:
undetectable		 2j5mA-5y3rA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0u NEOPULLULANASE 1

(Thermoactinomyces
vulgaris) 		no annotation 4 LEU A 344
PHE A 380
ILE A 393
ALA A 391
 None
 0.91A 2j5mA-5z0uA:
undetectable		 2j5mA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bt4 S-LAYER PROTEIN SAP

(Bacillus
anthracis) 		no annotation 4 PHE A  95
ILE A 107
VAL A 110
ALA A  76
 None
 0.93A 2j5mA-6bt4A:
undetectable		 2j5mA-6bt4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eo5 PPBBE-LIKE 1 D396N

(Physcomitrella
patens) 		no annotation 4 PHE A 492
ILE A 104
VAL A 127
ALA A  93
 None
 0.94A 2j5mA-6eo5A:
undetectable		 2j5mA-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6epi ZETA_1 TOXIN

(Neisseria
gonorrhoeae) 		no annotation 4 LEU B 195
ILE B 212
VAL B 230
ALA B 160
 None
 0.92A 2j5mA-6epiB:
undetectable		 2j5mA-6epiB:
undetectable