SIMILAR PATTERNS OF AMINO ACIDS FOR 2IZQ_D_DVAD8

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxd GA REPEAT BINDING
PROTEIN, ALPHA

(Mus musculus) 		PF02198
(SAM_PNT) 		4 VAL A 194
TRP A 241
VAL A 198
TRP A 189
 None
 1.42A 2izqC-1sxdA:
undetectable
2izqD-1sxdA:
undetectable		 2izqC-1sxdA:
11.76
2izqD-1sxdA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rj8 CARBOHYDRATE OXIDASE

(Microdochium
nivale) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 VAL A 348
TRP A 409
VAL A 344
TRP A 353
 None
 1.47A 2izqC-3rj8A:
undetectable
2izqD-3rj8A:
undetectable		 2izqC-3rj8A:
3.76
2izqD-3rj8A:
3.76