SIMILAR PATTERNS OF AMINO ACIDS FOR 2HKK_A_ALEA300_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ac5 | KEX1(DELTA)P (Saccharomycescerevisiae) |
PF00450(Peptidase_S10) | 4 | ASN A 212HIS A 448ASN A 379ILE A 395 | None | 1.23A | 2hkkA-1ac5A:undetectable | 2hkkA-1ac5A:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d0b | INTERNALIN B (Listeriamonocytogenes) |
PF12354(Internalin_N)PF12799(LRR_4) | 4 | ASN A 99ASN A 76ILE A 38GLN A 72 | None | 1.24A | 2hkkA-1d0bA:undetectable | 2hkkA-1d0bA:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3u | ASPARTASE (Bacillus sp.YM55-1) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 4 | ASN A 368ILE A 375GLN A 371THR A 37 | None | 1.27A | 2hkkA-1j3uA:undetectable | 2hkkA-1j3uA:20.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jd0 | CARBONIC ANHYDRASEXII (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 92THR A 200 | NoneNoneAZM A1400 (-3.2A)AZM A1400 (-3.3A) | 0.69A | 2hkkA-1jd0A:36.3 | 2hkkA-1jd0A:36.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js8 | HEMOCYANIN (Enteroctopusdofleini) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | HIS A2753ASN A2747ILE A2539GLN A2577 | None | 1.23A | 2hkkA-1js8A:undetectable | 2hkkA-1js8A:22.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kop | CARBONIC ANHYDRASE (Neisseriagonorrhoeae) |
PF00194(Carb_anhydrase) | 4 | ASN A 64HIS A 66GLN A 90THR A 178 | BME A 303 (-4.7A)BME A 303 (-3.6A)NoneAZI A 305 ( 4.2A) | 0.36A | 2hkkA-1kopA:29.5 | 2hkkA-1kopA:33.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfi | I-KAPPA-B-ALPHA (Homo sapiens) |
PF00023(Ank)PF12796(Ank_2) | 4 | ASN E 180HIS E 184ASN E 145ILE E 120 | None | 1.14A | 2hkkA-1nfiE:undetectable | 2hkkA-1nfiE:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nq6 | XYS1 (Streptomyceshalstedii) |
PF00331(Glyco_hydro_10) | 4 | ASN A 170HIS A 80GLN A 232THR A 41 | None | 1.22A | 2hkkA-1nq6A:undetectable | 2hkkA-1nq6A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p99 | HYPOTHETICAL PROTEINPG110 (Staphylococcusaureus) |
PF03180(Lipoprotein_9) | 4 | ASN A 90ILE A 239GLN A 93THR A 108 | None | 1.14A | 2hkkA-1p99A:undetectable | 2hkkA-1p99A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd1 | FORMIMINOTRANSFERASE-CYCLODEAMINASE (Sus scrofa) |
PF02971(FTCD)PF07837(FTCD_N) | 4 | HIS A 82ASN A 186GLN A 268THR A 44 | GOL A 480 ( 4.1A)FON A 330 (-4.0A)FON A 330 (-3.0A)FON A 330 (-3.1A) | 1.21A | 2hkkA-1qd1A:undetectable | 2hkkA-1qd1A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qho | ALPHA-AMYLASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | ASN A 337ASN A 342ILE A 435GLN A 345 | None | 1.20A | 2hkkA-1qhoA:undetectable | 2hkkA-1qhoA:17.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 92THR A 200 | NoneNoneAZM A 400 (-4.3A)AZM A 400 (-3.6A) | 0.81A | 2hkkA-1rj6A:37.1 | 2hkkA-1rj6A:37.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t5r | LUKS-PV (Staphylococcusphage PVL) |
PF07968(Leukocidin) | 4 | ASN A 262ASN A 233ILE A 158GLN A 77 | None | 0.71A | 2hkkA-1t5rA:undetectable | 2hkkA-1t5rA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uyv | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF01039(Carboxyl_trans) | 4 | ASN A1587ASN A1624ILE A1755THR A1726 | None | 1.13A | 2hkkA-1uyvA:undetectable | 2hkkA-1uyvA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x2b | PROLINEIMINOPEPTIDASE (Serratiamarcescens) |
PF00561(Abhydrolase_1) | 4 | ASN A 86HIS A 234ILE A 43GLN A 71 | None | 1.25A | 2hkkA-1x2bA:undetectable | 2hkkA-1x2bA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 4 | ASN A 101ASN A 97GLN A 494THR A 487 | None | 1.27A | 2hkkA-1ygpA:undetectable | 2hkkA-1ygpA:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ag1 | BENZALDEHYDE LYASE (Pseudomonasfluorescens) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ASN A 541HIS A 505ASN A 474GLN A 476 | None | 1.12A | 2hkkA-2ag1A:undetectable | 2hkkA-2ag1A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bkx | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Bacillussubtilis) |
PF01182(Glucosamine_iso) | 4 | ASN A 158ASN A 136ILE A 133THR A 146 | None | 1.23A | 2hkkA-2bkxA:undetectable | 2hkkA-2bkxA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0v | METHANOLDEHYDROGENASE LARGESUBUNIT (Hyphomicrobiumdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | ASN A 24ASN A 20ILE A 5THR A 28 | None | 1.26A | 2hkkA-2d0vA:undetectable | 2hkkA-2d0vA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ei9 | NON-LTRRETROTRANSPOSONR1BMKS ORF2 PROTEIN (Bombyx mori) |
PF14529(Exo_endo_phos_2) | 4 | ASN A 172ILE A 16GLN A 15THR A 131 | None | 1.06A | 2hkkA-2ei9A:undetectable | 2hkkA-2ei9A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2evv | HYPOTHETICAL PROTEINHP0218 (Helicobacterpylori) |
PF01161(PBP) | 4 | ASN A 98ILE A 93GLN A 95THR A 36 | None | 1.15A | 2hkkA-2evvA:undetectable | 2hkkA-2evvA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f5v | PYRANOSE 2-OXIDASE (Peniophora sp.SG) |
PF05199(GMC_oxred_C) | 4 | ASN A 585HIS A 553ILE A 603THR A 319 | None | 1.26A | 2hkkA-2f5vA:undetectable | 2hkkA-2f5vA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odl | ADHESIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 4 | ASN A 380ASN A 404ILE A 411GLN A 406 | None | 0.93A | 2hkkA-2odlA:undetectable | 2hkkA-2odlA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qiw | PEP PHOSPHONOMUTASE (Corynebacteriumglutamicum) |
PF13714(PEP_mutase) | 4 | ASN A 110ASN A 149ILE A 173THR A 209 | SO4 A 255 (-3.8A)NoneNoneGOL A 264 ( 3.9A) | 1.13A | 2hkkA-2qiwA:undetectable | 2hkkA-2qiwA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r7e | COAGULATION FACTORVIII (Homo sapiens) |
PF00754(F5_F8_type_C)PF07731(Cu-oxidase_2) | 4 | ASN B2019HIS B2082ILE B1940GLN B1874 | NAG B2431 ( 4.8A)NoneNoneNone | 1.20A | 2hkkA-2r7eB:undetectable | 2hkkA-2r7eB:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r7e | COAGULATION FACTORVIII (Homo sapiens) |
PF00754(F5_F8_type_C)PF07731(Cu-oxidase_2) | 4 | ASN B2019HIS B2082ILE B1940GLN B1938 | NAG B2431 ( 4.8A)NoneNoneNAG B2431 (-3.4A) | 1.19A | 2hkkA-2r7eB:undetectable | 2hkkA-2r7eB:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rkv | TRICHOTHECENE3-O-ACETYLTRANSFERASE (Fusariumgraminearum) |
PF02458(Transferase) | 4 | ASN A 356HIS A 355ILE A 212THR A 9 | None | 1.24A | 2hkkA-2rkvA:undetectable | 2hkkA-2rkvA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w5f | ENDO-1,4-BETA-XYLANASE Y (Ruminiclostridiumthermocellum) |
PF00331(Glyco_hydro_10)PF02018(CBM_4_9) | 4 | ASN A 394HIS A 276GLN A 457THR A 231 | NoneXYP A1001 (-3.9A)NoneNone | 1.20A | 2hkkA-2w5fA:undetectable | 2hkkA-2w5fA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wqw | INTERNALIN B (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 4 | ASN A 99ASN A 76ILE A 38GLN A 72 | PEG A1322 (-3.6A)NoneNoneNone | 1.27A | 2hkkA-2wqwA:undetectable | 2hkkA-2wqwA:25.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ww2 | ALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 4 | ASN A 194ASN A 96GLN A 90THR A 100 | NoneGOL A 803 (-4.6A)NoneNone | 1.27A | 2hkkA-2ww2A:undetectable | 2hkkA-2ww2A:16.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2znc | CARBONIC ANHYDRASEIV (Mus musculus) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 92THR A 200 | None | 0.35A | 2hkkA-2zncA:31.8 | 2hkkA-2zncA:35.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsi | PROBABLE GIBBERELLINRECEPTOR GID1L1 (Arabidopsisthaliana) |
PF07859(Abhydrolase_3) | 4 | ASN A 327HIS A 329ASN A 326THR A 318 | None | 1.17A | 2hkkA-2zsiA:undetectable | 2hkkA-2zsiA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3g | LUMAZINE PROTEIN (Photobacteriumkishitanii) |
PF00677(Lum_binding) | 4 | ASN A 82ASN A 45ILE A 12THR A 171 | None | 1.20A | 2hkkA-3a3gA:undetectable | 2hkkA-3a3gA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3g | LUMAZINE PROTEIN (Photobacteriumkishitanii) |
PF00677(Lum_binding) | 4 | ASN A 141ASN A 45ILE A 26THR A 171 | None | 1.14A | 2hkkA-3a3gA:undetectable | 2hkkA-3a3gA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1b | CARBONIC ANHYDRASE 1 (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 4 | ASN A 110HIS A 112GLN A 161THR A 261 | None | 0.33A | 2hkkA-3b1bA:25.4 | 2hkkA-3b1bA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9g | IAG-NUCLEOSIDEHYDROLASE (Trypanosomavivax) |
PF01156(IU_nuc_hydro) | 4 | ASN A 59HIS A 58ASN A 101ILE A 95 | None | 1.16A | 2hkkA-3b9gA:undetectable | 2hkkA-3b9gA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bvm | ENTEROTOXIN TYPE C-3 (Staphylococcusaureus) |
PF01123(Stap_Strp_toxin)PF02876(Stap_Strp_tox_C) | 4 | ASN A 220ILE A 161GLN A 157THR A 66 | None | 1.23A | 2hkkA-3bvmA:undetectable | 2hkkA-3bvmA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkz | DNA-DIRECTED RNAPOLYMERASE SUBUNIT B (Sulfolobussolfataricus) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 4 | ASN B 911HIS B 913ASN B 733ILE B 892 | None | 1.16A | 2hkkA-3hkzB:undetectable | 2hkkA-3hkzB:12.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kn3 | PUTATIVE PERIPLASMICPROTEIN (Wolinellasuccinogenes) |
PF12849(PBP_like_2) | 4 | ASN A 198ASN A 81ILE A 174THR A 123 | NoneNoneNoneGOL A 262 (-4.0A) | 1.21A | 2hkkA-3kn3A:undetectable | 2hkkA-3kn3A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kng | SNOAB (Streptomycesnogalater) |
PF03992(ABM) | 4 | ASN A 63HIS A 49ASN A 18THR A 36 | None | 1.21A | 2hkkA-3kngA:undetectable | 2hkkA-3kngA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxx | GTPASE IMAP FAMILYMEMBER 4 (Homo sapiens) |
PF04548(AIG1) | 4 | HIS A 57ASN A 48ILE A 50THR A 66 | NoneNoneNone MG A 402 (-2.9A) | 1.17A | 2hkkA-3lxxA:undetectable | 2hkkA-3lxxA:21.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 92THR A 200 | NoneNoneAZM A 264 (-4.1A)AZM A 264 (-3.5A) | 0.44A | 2hkkA-3ml5A:43.1 | 2hkkA-3ml5A:55.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ogk | CORONATINE-INSENSITIVE PROTEIN 1 (Arabidopsisthaliana) |
no annotation | 4 | ASN B 426ASN B 392ILE B 390THR B 451 | None | 0.98A | 2hkkA-3ogkB:undetectable | 2hkkA-3ogkB:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pvl | MYOSIN VIIA ISOFORM1 (Mus musculus) |
PF00784(MyTH4) | 4 | HIS A1015ILE A1045GLN A1178THR A1013 | None | 1.13A | 2hkkA-3pvlA:undetectable | 2hkkA-3pvlA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtp | ENOLASE 1 (Entamoebahistolytica) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | ASN A 433ILE A 361GLN A 365THR A 142 | None | 1.24A | 2hkkA-3qtpA:undetectable | 2hkkA-3qtpA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r6y | ASPARTASE (Bacillus sp.YM55-1) |
PF00206(Lyase_1) | 4 | ASN A 368ILE A 375GLN A 371THR A 37 | ASN A 368 ( 0.6A)ILE A 375 ( 0.7A)GLN A 371 ( 0.6A)THR A 37 ( 0.8A) | 1.26A | 2hkkA-3r6yA:undetectable | 2hkkA-3r6yA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rd8 | FUMARATE HYDRATASECLASS II (Mycolicibacteriumsmegmatis) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 4 | ASN A 132ASN A 111ILE A 84THR A 140 | None | 1.17A | 2hkkA-3rd8A:undetectable | 2hkkA-3rd8A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rrp | PROBABLE FUMARATEHYDRATASE FUM (Mycobacteroidesabscessus) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 4 | ASN A 133ASN A 110ILE A 83THR A 141 | None | 1.20A | 2hkkA-3rrpA:undetectable | 2hkkA-3rrpA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1s | RESTRICTIONENDONUCLEASE BPUSI (Bacilluspumilus) |
PF02384(N6_Mtase)PF15516(BpuSI_N) | 4 | ASN A 7ASN A 39ILE A 163GLN A 160 | None | 1.25A | 2hkkA-3s1sA:undetectable | 2hkkA-3s1sA:15.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uyq | CARBONIC ANHYDRASE 3 (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 92THR A 199 | None | 0.56A | 2hkkA-3uyqA:40.8 | 2hkkA-3uyqA:58.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3va7 | KLLA0E08119P (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | ASN A1318HIS A1315ILE A1557GLN A1638 | None | 1.27A | 2hkkA-3va7A:undetectable | 2hkkA-3va7A:12.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aio | LIMIT DEXTRINASE (Hordeum vulgare) |
PF02922(CBM_48)PF11852(DUF3372) | 4 | ASN A 598ASN A 540ILE A 547THR A 619 | None | 1.19A | 2hkkA-4aioA:undetectable | 2hkkA-4aioA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4apb | FUMARATE HYDRATASECLASS II (Mycobacteriumtuberculosis) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 4 | ASN A 134ASN A 113ILE A 86THR A 142 | None | 1.17A | 2hkkA-4apbA:undetectable | 2hkkA-4apbA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7q | RALF,PROLINE/BETAINETRANSPORTER (Legionellapneumophila;Rickettsiaprowazekii) |
PF01369(Sec7) | 4 | ASN A 207ASN A 206ILE A 294GLN A 204 | None | 1.23A | 2hkkA-4d7qA:undetectable | 2hkkA-4d7qA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6t | MOLYBDENUM STORAGEPROTEIN SUBUNIT BETA (Azotobactervinelandii) |
PF00696(AA_kinase) | 4 | HIS B 70ILE B 266GLN B 244THR B 39 | NonePO4 B 303 ( 4.3A)NoneNone | 1.09A | 2hkkA-4f6tB:undetectable | 2hkkA-4f6tB:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f9u | CG32412 (Drosophilamelanogaster) |
PF04389(Peptidase_M28) | 4 | ASN A 141HIS A 40ASN A 315ILE A 220 | None | 1.20A | 2hkkA-4f9uA:undetectable | 2hkkA-4f9uA:20.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4g7a | CARBONATEDEHYDRATASE (Sulfurihydrogenibiumsp. YO3AOP1) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 87THR A 175 | NoneNoneAZM A 302 (-4.4A)AZM A 302 (-3.4A) | 0.41A | 2hkkA-4g7aA:29.8 | 2hkkA-4g7aA:34.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gnk | 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATEPHOSPHODIESTERASEBETA-3 (Homo sapiens) |
PF00168(C2)PF00387(PI-PLC-Y)PF00388(PI-PLC-X)PF09279(EF-hand_like) | 4 | ASN B 305ILE B 250GLN B 254THR B 842 | None | 1.24A | 2hkkA-4gnkB:undetectable | 2hkkA-4gnkB:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpv | S-ADENOSYLMETHIONINESYNTHASE (Sulfolobussolfataricus) |
PF01941(AdoMet_Synthase) | 4 | ASN A 311HIS A 59ASN A 314ILE A 349 | None | 1.16A | 2hkkA-4hpvA:undetectable | 2hkkA-4hpvA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ib2 | PUTATIVE LIPOPROTEIN ([Ruminococcus]gnavus) |
PF03180(Lipoprotein_9) | 4 | ASN A 89ILE A 237GLN A 92THR A 106 | None | 1.07A | 2hkkA-4ib2A:undetectable | 2hkkA-4ib2A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ikn | AP-3 COMPLEX SUBUNITMU-1 (Rattusnorvegicus) |
PF00928(Adap_comp_sub) | 4 | HIS A 313ASN A 374ILE A 190GLN A 415 | HIS A 313 ( 1.0A)ASN A 374 ( 0.6A)ILE A 190 ( 0.7A)GLN A 415 ( 0.6A) | 1.16A | 2hkkA-4iknA:undetectable | 2hkkA-4iknA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nqy | ISOPROPYLMALATE/CITRAMALATE ISOMERASELARGE SUBUNIT (Methanocaldococcusjannaschii) |
PF00330(Aconitase) | 4 | HIS A 103ASN A 387ILE A 182THR A 127 | None | 1.18A | 2hkkA-4nqyA:undetectable | 2hkkA-4nqyA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4om9 | SERINE PROTEASE PET (Escherichiacoli) |
PF02395(Peptidase_S6) | 4 | ASN A 73ILE A 104GLN A 105THR A 54 | None | 1.26A | 2hkkA-4om9A:undetectable | 2hkkA-4om9A:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ook | METHIONINEAMINOPEPTIDASE 2 (Mycobacteriumtuberculosis) |
PF00557(Peptidase_M24) | 4 | ASN A 144ASN A 129ILE A 127THR A 167 | None | 1.22A | 2hkkA-4ookA:undetectable | 2hkkA-4ookA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqr | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 4 | ASN A 67ASN A 96ILE A 236THR A 286 | HEM A 501 ( 4.8A)None2UO A 502 (-4.1A)2UO A 502 ( 4.4A) | 1.08A | 2hkkA-4oqrA:undetectable | 2hkkA-4oqrA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmd | ENDO-1,4-BETA-XYLANASE (Caldicellulosiruptorbescii) |
PF00331(Glyco_hydro_10) | 4 | ASN A 182HIS A 87GLN A 244THR A 48 | NoneBXP A 401 (-3.9A)NoneNone | 1.18A | 2hkkA-4pmdA:undetectable | 2hkkA-4pmdA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pq8 | DESIGNED PROTEINOR465 (syntheticconstruct) |
PF00560(LRR_1)PF12354(Internalin_N)PF13855(LRR_8) | 4 | ASN A 71ASN A 48ILE A 10GLN A 44 | None | 1.26A | 2hkkA-4pq8A:undetectable | 2hkkA-4pq8A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psj | OR464 (syntheticconstruct) |
PF12354(Internalin_N)PF13516(LRR_6)PF13855(LRR_8) | 4 | ASN A 71ASN A 48ILE A 10GLN A 44 | None | 1.26A | 2hkkA-4psjA:undetectable | 2hkkA-4psjA:22.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | ASN A 62ASN A 67ILE A 91GLN A 92THR A 200 | None | 0.13A | 2hkkA-4qk3A:44.3 | 2hkkA-4qk3A:95.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1i | AMINOBENZOYL-GLUTAMATE TRANSPORTER (Neisseriagonorrhoeae) |
PF03806(ABG_transport) | 4 | ASN A 453ASN A 410ILE A 413GLN A 419 | None | 1.21A | 2hkkA-4r1iA:undetectable | 2hkkA-4r1iA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5c | LEUCINE RICH REPEATPROTEIN (syntheticconstruct) |
PF12354(Internalin_N)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 4 | ASN A 63ASN A 40ILE A 2GLN A 36 | None | 1.26A | 2hkkA-4r5cA:undetectable | 2hkkA-4r5cA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5d | LEUCINE RICH REPEATPROTEIN (syntheticconstruct) |
PF12354(Internalin_N)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 4 | ASN A 63ASN A 40ILE A 2GLN A 36 | None | 1.21A | 2hkkA-4r5dA:undetectable | 2hkkA-4r5dA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6f | LEUCINE RICH REPEATDLRR_I (syntheticconstruct) |
PF12354(Internalin_N)PF13855(LRR_8) | 4 | ASN A 63ASN A 40ILE A 2GLN A 36 | None | 1.20A | 2hkkA-4r6fA:undetectable | 2hkkA-4r6fA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6g | LEUCINE RICH REPEATSDLRR_K (syntheticconstruct) |
PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 4 | ASN A 63ASN A 40ILE A 2GLN A 36 | None | 1.20A | 2hkkA-4r6gA:undetectable | 2hkkA-4r6gA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8b | EXO-XYLOGLUCANASE (unculturedbacterium) |
PF00150(Cellulase) | 4 | ASN A 500ASN A 447ILE A 439GLN A 443 | XYS A 618 (-3.1A)XYS A 618 (-3.4A)NoneXYS A 618 ( 4.2A) | 1.20A | 2hkkA-4w8bA:undetectable | 2hkkA-4w8bA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8l | ENDO-1,4-BETA-XYLANASE C (Paenibacillusbarcinonensis) |
PF00331(Glyco_hydro_10) | 4 | ASN A 528HIS A 420GLN A 590THR A 381 | None | 1.26A | 2hkkA-4w8lA:undetectable | 2hkkA-4w8lA:17.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 87THR A 175 | NoneNoneAZM A 302 (-4.3A)AZM A 302 (-3.3A) | 0.34A | 2hkkA-4x5sA:29.9 | 2hkkA-4x5sA:38.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xz5 | CARBONIC ANHYDRASE,ALPHA FAMILY (Hydrogenovibriocrunogenus) |
PF00194(Carb_anhydrase) | 4 | ASN A 138HIS A 140GLN A 163THR A 253 | NoneNoneNoneBCT A 402 ( 4.4A) | 0.38A | 2hkkA-4xz5A:29.4 | 2hkkA-4xz5A:32.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 4 | ASN A 299ILE A 173GLN A 170THR A 121 | NoneNoneBG6 A 501 (-3.0A)None | 1.21A | 2hkkA-4zfmA:undetectable | 2hkkA-4zfmA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxi | TYROCIDINESYNTHETASE 3 (Acinetobacterbaumannii) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 4 | HIS A 996ILE A 928GLN A 927THR A1034 | None | 1.16A | 2hkkA-4zxiA:undetectable | 2hkkA-4zxiA:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II SUBUNITALPHAMETHYL-COENZYME MREDUCTASE II SUBUNITGAMMA (Methanothermobactermarburgensis) |
PF02241(MCR_beta)PF02249(MCR_alpha)PF02745(MCR_alpha_N)PF02783(MCR_beta_N) | 4 | ASN A 479HIS B 384ASN A 458ILE A 462 | SMC A 454 ( 3.6A)SMC A 454 ( 4.3A)SMC A 454 ( 3.9A)None | 1.11A | 2hkkA-5a8rA:undetectable | 2hkkA-5a8rA:18.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cjf | CARBONIC ANHYDRASE14 (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64GLN A 92THR A 200 | GOL A 303 (-3.9A)NoneGOL A 303 (-3.2A)GOL A 303 ( 3.5A) | 0.36A | 2hkkA-5cjfA:36.6 | 2hkkA-5cjfA:36.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5exr | DNA POLYMERASE ALPHACATALYTIC SUBUNITDNA POLYMERASE ALPHASUBUNIT B (Homo sapiens) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1)PF04042(DNA_pol_E_B)PF08418(Pol_alpha_B_N)PF08996(zf-DNA_Pol) | 4 | ASN C 549HIS C 553ILE C 728THR D 309 | None | 1.04A | 2hkkA-5exrC:undetectable | 2hkkA-5exrC:12.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 5 | ASN X 61HIS X 63ASN X 66GLN X 91THR X 198 | None | 0.27A | 2hkkA-5eztX:44.2 | 2hkkA-5eztX:80.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3v | CAG8 (Helicobacterpylori) |
PF03524(CagX) | 4 | HIS A 18ILE A 24GLN A 10THR A 39 | None | 1.14A | 2hkkA-5h3vA:undetectable | 2hkkA-5h3vA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hkq | CDII IMMUNITYPROTEINCONTACT-DEPENDENTINHIBITOR A (Escherichiacoli) |
PF14436(EndoU_bacteria)no annotation | 4 | ASN I 2ASN I 28ILE I 50THR A 305 | None | 1.14A | 2hkkA-5hkqI:undetectable | 2hkkA-5hkqI:18.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 4 | ASN A 69HIS A 71GLN A 94THR A 183 | None | 0.38A | 2hkkA-5hpjA:29.4 | 2hkkA-5hpjA:35.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | ASN A1318HIS A1315ILE A1557GLN A1638 | None | 1.21A | 2hkkA-5i8iA:undetectable | 2hkkA-5i8iA:9.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iwd | DNA POLYMERASEPROCESSIVITY FACTOR (Humanbetaherpesvirus5) |
PF03325(Herpes_PAP) | 4 | ASN A 89ASN A 82ILE A 80THR A 94 | None | 0.94A | 2hkkA-5iwdA:undetectable | 2hkkA-5iwdA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5p | PRE-MRNA-SPLICINGHELICASE BRR2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | ASN A 529ILE A 502GLN A 503THR A 496 | None | 1.16A | 2hkkA-5m5pA:undetectable | 2hkkA-5m5pA:9.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5npr | UDP-N-ACETYLGLUCOSAMINE--PEPTIDEN-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDASUBUNIT (Homo sapiens) |
no annotation | 4 | ASN A 638ASN A 628ILE A 667THR A 633 | None | 1.08A | 2hkkA-5nprA:undetectable | 2hkkA-5nprA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o4g | RECEPTORTYROSINE-PROTEINKINASE ERBB-2 (Homo sapiens) |
no annotation | 4 | ASN C 476HIS C 473ASN C 449ILE C 390 | None | 1.23A | 2hkkA-5o4gC:undetectable | 2hkkA-5o4gC:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u24 | PUTATIVEAMINOTRANSFERASE (Campylobacterjejuni) |
PF01041(DegT_DnrJ_EryC1) | 4 | ASN A 185HIS A 279ASN A 248ILE A 163 | None | 1.19A | 2hkkA-5u24A:undetectable | 2hkkA-5u24A:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjj | MULTI DRUG EFFLUXTRANSPORTER (Camelina sativa) |
PF01554(MatE) | 4 | ASN A 405ASN A 406ILE A 262THR A 386 | None | 1.01A | 2hkkA-5xjjA:undetectable | 2hkkA-5xjjA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3x | BETA-XYLANASE (Caldicellulosiruptorowensensis) |
no annotation | 4 | ASN A 182HIS A 86GLN A 244THR A 47 | None | 1.24A | 2hkkA-5y3xA:undetectable | 2hkkA-5y3xA:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yjh | PERIOSTIN (Homo sapiens) |
no annotation | 4 | HIS A 198ASN A 201ILE A 68THR A 205 | NoneNoneNone MG A 728 (-3.6A) | 1.07A | 2hkkA-5yjhA:undetectable | 2hkkA-5yjhA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ze8 | CYTOCHROME C552 (Thermochromatiumtepidum) |
no annotation | 4 | ASN A 106HIS A 38ASN A 126THR A 132 | None | 1.17A | 2hkkA-5ze8A:undetectable | 2hkkA-5ze8A:11.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eki | CARBONIC ANHYDRASE (Persephonellamarina) |
no annotation | 4 | ASN A 90HIS A 92GLN A 115THR A 203 | None | 0.46A | 2hkkA-6ekiA:29.9 | 2hkkA-6ekiA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fe1 | CARBONIC ANHYDRASE 9 (Homo sapiens) |
no annotation | 4 | ASN A 62HIS A 64GLN A 92THR A 200 | V14 A 302 (-3.4A)NoneV14 A 302 (-3.8A)V14 A 302 (-3.5A) | 0.40A | 2hkkA-6fe1A:33.6 | 2hkkA-6fe1A:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fhf | - (-) |
no annotation | 4 | ASN A 158HIS A 95ILE A 216THR A 266 | None | 1.17A | 2hkkA-6fhfA:undetectable | 2hkkA-6fhfA:undetectable |