SIMILAR PATTERNS OF AMINO ACIDS FOR 2HA6_A_SCKA902
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1b41 | ACETYLCHOLINESTERASE (Homo sapiens) |
PF00135(COesterase) | 7 | GLU A 81GLU A 84MET A 85ASN A 87ASP A 131GLU A 452TYR A 465 | None | 0.70A | 2ha6A-1b41A:63.1 | 2ha6A-1b41A:88.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1b41 | ACETYLCHOLINESTERASE (Homo sapiens) |
PF00135(COesterase) | 7 | GLU A 81MET A 85ASN A 87ASP A 131THR A 436GLU A 452TYR A 465 | None | 0.48A | 2ha6A-1b41A:63.1 | 2ha6A-1b41A:88.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1c2o | ACETYLCHOLINESTERASE (Electrophoruselectricus) |
PF00135(COesterase) | 10 | GLU A 81GLU A 84MET A 85ASN A 87ASP A 131THR A 436GLU A 452LEU A 457LEU A 463TYR A 465 | None | 0.49A | 2ha6A-1c2oA:63.9 | 2ha6A-1c2oA:99.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1c2o | ACETYLCHOLINESTERASE (Electrophoruselectricus) |
PF00135(COesterase) | 6 | GLU A 81GLU A 84MET A 85ASN A 87LEU A 463TYR A 465 | None | 1.45A | 2ha6A-1c2oA:63.9 | 2ha6A-1c2oA:99.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gqr | ACETYLCHOLINESTERASE (Tetronarcecalifornica) |
PF00135(COesterase) | 8 | GLU A 82MET A 83ASN A 85ASP A 128GLU A 445LEU A 450LEU A 456TYR A 458 | None | 0.59A | 2ha6A-1gqrA:60.9 | 2ha6A-1gqrA:58.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lwh | 4-ALPHA-GLUCANOTRANSFERASE (Thermotogamaritima) |
PF00128(Alpha-amylase)PF09178(DUF1945) | 5 | ASN A 276GLU A 315LEU A 35LEU A 32TYR A 31 | None | 1.35A | 2ha6A-1lwhA:undetectable | 2ha6A-1lwhA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n8y | PROTOONCOPROTEIN (Rattusnorvegicus) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 5 | GLU C 39MET C 62ASN C 37LEU C 119LEU C 116 | None | 1.49A | 2ha6A-1n8yC:undetectable | 2ha6A-1n8yC:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nf6 | BACTERIOFERRITIN (Desulfovibriodesulfuricans) |
PF00210(Ferritin) | 5 | GLU A 99ASP A 55THR A 102GLU A 23TYR A 106 | FE A 200 (-2.4A)NoneNoneNoneNone | 1.43A | 2ha6A-1nf6A:undetectable | 2ha6A-1nf6A:15.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qon | ACETYLCHOLINESTERASE (Drosophilamelanogaster) |
PF00135(COesterase) | 6 | GLU A 81ASN A 84ASP A 160GLU A 485LEU A 496TYR A 498 | NoneNoneNoneNoneNAG A 991 (-4.1A)None | 0.79A | 2ha6A-1qonA:56.8 | 2ha6A-1qonA:38.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qon | ACETYLCHOLINESTERASE (Drosophilamelanogaster) |
PF00135(COesterase) | 6 | GLU A 81ASN A 84THR A 469GLU A 485LEU A 496TYR A 498 | NoneNoneNoneNoneNAG A 991 (-4.1A)None | 0.93A | 2ha6A-1qonA:56.8 | 2ha6A-1qonA:38.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uok | OLIGO-1,6-GLUCOSIDASE (Bacillus cereus) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 5 | ASN A 327GLU A 369LEU A 43LEU A 40TYR A 39 | None | 1.26A | 2ha6A-1uokA:undetectable | 2ha6A-1uokA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwy | CARBOXYPEPTIDASE M (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 5 | GLU A 153ASN A 109GLU A 12LEU A 15LEU A 28 | None | 1.26A | 2ha6A-1uwyA:3.0 | 2ha6A-1uwyA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dby | GTP-BINDING PROTEIN (Thermusthermophilus) |
PF01926(MMR_HSR1)PF06071(YchF-GTPase_C) | 5 | ASN A 19GLU A 212LEU A 215LEU A 266TYR A 264 | None | 1.34A | 2ha6A-2dbyA:2.1 | 2ha6A-2dbyA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gqq | LEUCINE-RESPONSIVEREGULATORY PROTEIN (Escherichiacoli) |
PF01037(AsnC_trans_reg)PF13412(HTH_24) | 5 | ASN A 94THR A 146LEU A 130LEU A 131TYR A 127 | None | 1.45A | 2ha6A-2gqqA:undetectable | 2ha6A-2gqqA:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivf | ETHYLBENZENEDEHYDROGENASEALPHA-SUBUNIT (Aromatoleumaromaticum) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | GLU A 532MET A 534THR A 775LEU A 506TYR A 490 | None | 1.32A | 2ha6A-2ivfA:undetectable | 2ha6A-2ivfA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nn6 | EXOSOME COMPLEXEXONUCLEASE RRP43 (Homo sapiens) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 5 | GLU C 215ASN C 147THR C 204LEU C 248LEU C 243 | None | 1.50A | 2ha6A-2nn6C:undetectable | 2ha6A-2nn6C:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pwh | SUCROSE ISOMERASE ([Pseudomonas]mesoacidophila) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 5 | ASN A 325GLU A 368LEU A 44LEU A 41TYR A 40 | None | 1.41A | 2ha6A-2pwhA:undetectable | 2ha6A-2pwhA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdf | PHOSPHOENOLPYRUVATE-PROTEINPHOSPHOTRANSFERASE (Escherichiacoli) |
PF00391(PEP-utilizers)PF02896(PEP-utilizers_C)PF05524(PEP-utilisers_N) | 5 | GLU A 445GLU A 405LEU A 370LEU A 374TYR A 409 | None | 1.36A | 2ha6A-2xdfA:undetectable | 2ha6A-2xdfA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ybx | PHOSPHATIDYLINOSITOL-5-PHOSPHATE4-KINASE TYPE-2ALPHA (Homo sapiens) |
PF01504(PIP5K) | 5 | GLU A 154MET A 155ASN A 157THR A 196LEU A 101 | None | 1.49A | 2ha6A-2ybxA:undetectable | 2ha6A-2ybxA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfn | ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK ([Ruminococcus]gnavus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 5 | GLU A 260ASN A 87GLU A 76LEU A 148TYR A 150 | None | 1.40A | 2ha6A-2yfnA:undetectable | 2ha6A-2yfnA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ynm | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT BLIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Prochlorococcusmarinus) |
PF00148(Oxidored_nitro)PF08369(PCP_red) | 5 | GLU C 57GLU D 358LEU D 355LEU D 5TYR D 354 | None | 1.33A | 2ha6A-2ynmC:2.8 | 2ha6A-2ynmC:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ze0 | ALPHA-GLUCOSIDASE (Geobacillus sp.HTA-462) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 5 | ASN A 324GLU A 366LEU A 43LEU A 40TYR A 39 | None | 1.40A | 2ha6A-2ze0A:undetectable | 2ha6A-2ze0A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgt | PUTATIVEPHOSPHOLIPASE B-LIKE2 28 KDA FORMPUTATIVEPHOSPHOLIPASE B-LIKE2 40 KDA FORM (Mus musculus) |
PF04916(Phospholip_B) | 5 | GLU B 350ASN B 381GLU A 232LEU A 235TYR A 156 | None NA B 606 ( 4.8A)NoneNoneACT A 1 ( 4.7A) | 1.41A | 2ha6A-3fgtB:undetectable | 2ha6A-3fgtB:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgw | PUTATIVEPHOSPHOLIPASE B-LIKE2 (Mus musculus) |
PF04916(Phospholip_B) | 5 | GLU A 350ASN A 381GLU A 232LEU A 235TYR A 156 | None | 1.40A | 2ha6A-3fgwA:undetectable | 2ha6A-3fgwA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iec | SERINE/THREONINE-PROTEIN KINASE MARK2 (Homo sapiens) |
PF00069(Pkinase)PF00627(UBA) | 5 | GLU A 199ASN A 198ASP A 232GLU A 230LEU A 295 | None | 1.10A | 2ha6A-3iecA:undetectable | 2ha6A-3iecA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ilv | GLUTAMINE-DEPENDENTNAD(+) SYNTHETASE (Cytophagahutchinsonii) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 5 | GLU A 408GLU A 405GLU A 415LEU A 422LEU A 431 | None | 1.40A | 2ha6A-3ilvA:undetectable | 2ha6A-3ilvA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rhd | LACTALDEHYDEDEHYDROGENASE (Methanocaldococcusjannaschii) |
PF00171(Aldedh) | 5 | GLU A 453ASN A 159GLU A 241LEU A 240LEU A 442 | None | 1.30A | 2ha6A-3rhdA:undetectable | 2ha6A-3rhdA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4p | INTEGRIN ALPHA-4 (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 5 | GLU A 562ASP A 408LEU A 427LEU A 9TYR A 11 | None CA A 603 (-3.3A)NoneNoneNone | 1.49A | 2ha6A-3v4pA:undetectable | 2ha6A-3v4pA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aie | GLUCAN1,6-ALPHA-GLUCOSIDASE (Lactobacillusacidophilus) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 5 | ASN A 314GLU A 356LEU A 42LEU A 39TYR A 38 | None | 1.28A | 2ha6A-4aieA:undetectable | 2ha6A-4aieA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cmr | GLYCOSYLHYDROLASE/DEACETYLASE FAMILY PROTEIN (Pyrococcus sp.ST04) |
no annotation | 5 | ASN A 488GLU A 368LEU A 365LEU A 503TYR A 507 | None | 0.94A | 2ha6A-4cmrA:undetectable | 2ha6A-4cmrA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4efh | ACTIN-1 (Acanthamoebacastellanii) |
PF00022(Actin) | 5 | GLU A 270MET A 269THR A 160LEU A 185LEU A 261 | None | 1.48A | 2ha6A-4efhA:undetectable | 2ha6A-4efhA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4it1 | PUTATIVE GLUCARATEDEHYDRATASE (Pseudomonasfluorescens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | GLU A 47GLU A 358LEU A 365LEU A 329TYR A 350 | None | 1.23A | 2ha6A-4it1A:undetectable | 2ha6A-4it1A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j3b | M1 FAMILYAMINOPEPTIDASE (Plasmodiumfalciparum) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 5 | ASN A 458GLU A 957LEU A 958LEU A 476TYR A 418 | None | 1.42A | 2ha6A-4j3bA:undetectable | 2ha6A-4j3bA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj3 | INTRON-BINDINGPROTEIN AQUARIUS (Homo sapiens) |
PF13086(AAA_11)PF13087(AAA_12)PF16399(Aquarius_N) | 5 | GLU A1069ASN A 469LEU A1078LEU A 850TYR A1056 | None | 1.30A | 2ha6A-4pj3A:undetectable | 2ha6A-4pj3A:16.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qww | ACETYLCHOLINESTERASE (Bungarusfasciatus) |
PF00135(COesterase) | 8 | GLU A 82MET A 83ASN A 85ASP A 128GLU A 445LEU A 450LEU A 456TYR A 458 | NoneNoneNoneNAG A 608 ( 4.7A)NoneNoneNAG A 608 ( 4.5A)None | 0.35A | 2ha6A-4qwwA:62.0 | 2ha6A-4qwwA:64.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wk4 | INTEGRIN ALPHA-5 (Homo sapiens) |
PF01839(FG-GAP) | 5 | ASP A 311THR A 341GLU A 279LEU A 309TYR A 325 | None | 1.43A | 2ha6A-4wk4A:undetectable | 2ha6A-4wk4A:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb3 | GLUCAN1,6-ALPHA-GLUCOSIDASE (Streptococcusmutans) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 5 | ASN A 311GLU A 353LEU A 43LEU A 40TYR A 39 | None | 1.24A | 2ha6A-4xb3A:undetectable | 2ha6A-4xb3A:20.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xii | CHOLINESTERASE (Homo sapiens) |
PF00135(COesterase) | 6 | GLU A 80MET A 81ASN A 83GLU A 443LEU A 448TYR A 456 | None | 0.69A | 2ha6A-4xiiA:61.8 | 2ha6A-4xiiA:52.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y7p | ALKALINE D-PEPTIDASE (Bacillus cereus) |
PF00144(Beta-lactamase) | 5 | GLU A 196GLU A 193ASN A 189LEU A 203LEU A 205 | None | 1.39A | 2ha6A-4y7pA:undetectable | 2ha6A-4y7pA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anc | RIBOSOME MATURATIONPROTEIN SBDS (Homo sapiens) |
PF01172(SBDS)PF09377(SBDS_C) | 5 | GLU J 219ASP J 213THR J 228LEU J 193LEU J 190 | A N2522 ( 3.7A)NoneNoneNoneNone | 1.44A | 2ha6A-5ancJ:undetectable | 2ha6A-5ancJ:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 5 | GLU A2091GLU A2025ASN A2126LEU A2055LEU A2056 | None | 1.48A | 2ha6A-5b4xA:undetectable | 2ha6A-5b4xA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5daj | NALD (Pseudomonasaeruginosa) |
PF00440(TetR_N)PF08361(TetR_C_2) | 5 | GLU A 60MET A 61ASN A 63THR A 31LEU A 24 | None | 1.34A | 2ha6A-5dajA:undetectable | 2ha6A-5dajA:16.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jx5 | GLUCANASE (Orpinomyces sp.Y102) |
PF01341(Glyco_hydro_6) | 5 | GLU A 246THR A 325LEU A 297LEU A 343TYR A 339 | None | 1.34A | 2ha6A-5jx5A:undetectable | 2ha6A-5jx5A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp4 | PENICILLIN-BINDINGPROTEIN 2 (PBP2) (Helicobacterpylori) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | ASN A 402GLU A 192LEU A 163LEU A 275TYR A 153 | None | 1.50A | 2ha6A-5lp4A:undetectable | 2ha6A-5lp4A:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tu0 | LMO2125 PROTEIN (Listeriamonocytogenes) |
PF13416(SBP_bac_8) | 5 | GLU A 165ASN A 182LEU A 198LEU A 290TYR A 202 | PGE A 503 (-3.8A)NoneNoneNoneNone | 1.48A | 2ha6A-5tu0A:undetectable | 2ha6A-5tu0A:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wch | PROBABLE UBIQUITINCARBOXYL-TERMINALHYDROLASE FAF-X (Homo sapiens) |
no annotation | 5 | GLU A1915MET A1916ASN A1918LEU A1951TYR A1953 | None | 1.39A | 2ha6A-5wchA:undetectable | 2ha6A-5wchA:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xhq | APOLIPOPROTEINN-ACYLTRANSFERASE (Escherichiacoli) |
PF00795(CN_hydrolase) | 5 | GLU A 267GLU A 274LEU A 281LEU A 319TYR A 325 | None | 1.16A | 2ha6A-5xhqA:undetectable | 2ha6A-5xhqA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyh | CBSA (Xanthomonasoryzae) |
no annotation | 5 | GLU A 178THR A 264LEU A 232LEU A 310TYR A 306 | None | 1.34A | 2ha6A-5xyhA:undetectable | 2ha6A-5xyhA:9.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydj | ACETYLCHOLINESTERASE (Anophelesgambiae) |
no annotation | 5 | MET A 244ASN A 246ASP A 289LEU A 616TYR A 618 | None | 0.76A | 2ha6A-5ydjA:59.9 | 2ha6A-5ydjA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydj | ACETYLCHOLINESTERASE (Anophelesgambiae) |
no annotation | 5 | MET A 244ASN A 246GLU A 610LEU A 616TYR A 618 | None | 1.20A | 2ha6A-5ydjA:59.9 | 2ha6A-5ydjA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykb | TREHALOSE SYNTHASE (Deinococcusradiodurans) |
no annotation | 5 | ASN A 317GLU A 386LEU A 46LEU A 43TYR A 42 | None | 1.33A | 2ha6A-5ykbA:undetectable | 2ha6A-5ykbA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6arx | ACETYLCHOLINESTERASE (Anophelesgambiae) |
no annotation | 5 | MET A 244ASN A 246ASP A 289LEU A 616TYR A 618 | None | 0.60A | 2ha6A-6arxA:57.2 | 2ha6A-6arxA:9.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6arx | ACETYLCHOLINESTERASE (Anophelesgambiae) |
no annotation | 5 | MET A 244ASN A 246GLU A 610LEU A 616TYR A 618 | None | 1.28A | 2ha6A-6arxA:57.2 | 2ha6A-6arxA:9.77 |