SIMILAR PATTERNS OF AMINO ACIDS FOR 2HA4_B_ACHB602

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		4 TYR A  72
TYR A 124
TRP A 286
TYR A 341
 None
 0.66A 2ha4B-1b41A:
63.1		 2ha4B-1b41A:
88.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 TYR A  72
TYR A 124
TRP A 286
TYR A 341
 None
 0.17A 2ha4B-1c2oA:
63.5		 2ha4B-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		4 TYR A  70
TYR A 121
TRP A 279
TYR A 334
 None
 0.60A 2ha4B-1gqrA:
62.0		 2ha4B-1gqrA:
58.60