SIMILAR PATTERNS OF AMINO ACIDS FOR 2H42_C_VIAC903_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ac5 | KEX1(DELTA)P (Saccharomycescerevisiae) |
PF00450(Peptidase_S10) | 3 | ASN A 103ILE A 26MET A 29 | None | 0.80A | 2h42C-1ac5A:0.0 | 2h42C-1ac5A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amu | GRAMICIDINSYNTHETASE 1 (Brevibacillusbrevis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 3 | ASN A 71ILE A 58MET A 241 | None | 0.80A | 2h42C-1amuA:0.0 | 2h42C-1amuA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bg6 | N-(1-D-CARBOXYLETHYL)-L-NORVALINEDEHYDROGENASE (Arthrobactersp. 1C) |
PF02317(Octopine_DH)PF02558(ApbA) | 3 | ASN A 277ILE A 226MET A 201 | None | 0.65A | 2h42C-1bg6A:0.0 | 2h42C-1bg6A:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1byw | PROTEIN (HUMAN ERGPOTASSIUM CHANNEL) (Homo sapiens) |
PF13426(PAS_9) | 3 | ASN A 45ILE A 42MET A 124 | None | 0.75A | 2h42C-1bywA:undetectable | 2h42C-1bywA:13.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm0 | SHIGA TOXIN ASUBUNIT (Shigelladysenteriae) |
PF00161(RIP) | 3 | ASN A 202ILE A 174MET A 192 | None | 0.69A | 2h42C-1dm0A:undetectable | 2h42C-1dm0A:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ef5 | RGL (Mus musculus) |
PF00788(RA) | 3 | ASN A 659ILE A 654MET A 683 | None | 0.84A | 2h42C-1ef5A:undetectable | 2h42C-1ef5A:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1feh | PROTEIN (PERIPLASMICHYDROGENASE 1) (Clostridiumpasteurianum) |
PF02256(Fe_hyd_SSU)PF02906(Fe_hyd_lg_C)PF12838(Fer4_7)PF13510(Fer2_4) | 3 | ASN A 216ILE A 379MET A 387 | None | 0.85A | 2h42C-1fehA:0.0 | 2h42C-1fehA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fkm | PROTEIN (GYP1P) (Saccharomycescerevisiae) |
PF00566(RabGAP-TBC) | 3 | ASN A 381ILE A 348MET A 494 | None | 0.79A | 2h42C-1fkmA:0.0 | 2h42C-1fkmA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i5n | CHEMOTAXIS PROTEINCHEA (Salmonellaenterica) |
PF01627(Hpt) | 3 | ASN A 89ILE A 119MET A 69 | None | 0.83A | 2h42C-1i5nA:0.5 | 2h42C-1i5nA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iwa | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE/OXYGENASE LARGE SUBUNIT (Galdieriapartita) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | ASN A 207ILE A 265MET A 280 | None | 0.83A | 2h42C-1iwaA:0.0 | 2h42C-1iwaA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jof | CARBOXY-CIS,CIS-MUCONATE CYCLASE (Neurosporacrassa) |
PF10282(Lactonase) | 3 | ASN A 205ILE A 295MET A 269 | None | 0.82A | 2h42C-1jofA:undetectable | 2h42C-1jofA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l3w | EP-CADHERIN (Xenopus laevis) |
PF00028(Cadherin) | 3 | ASN A 27ILE A 24MET A 92 | None | 0.75A | 2h42C-1l3wA:undetectable | 2h42C-1l3wA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqt | POLYPROTEIN CAPSIDPROTEIN (Enterovirus B) |
PF00073(Rhv) | 3 | ASN B 217ILE B 205MET B 202 | None | 0.82A | 2h42C-1mqtB:undetectable | 2h42C-1mqtB:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nq6 | XYS1 (Streptomyceshalstedii) |
PF00331(Glyco_hydro_10) | 3 | ASN A 170ILE A 198MET A 187 | None | 0.81A | 2h42C-1nq6A:0.0 | 2h42C-1nq6A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogo | DEXTRANASE (Talaromycesminioluteus) |
PF03718(Glyco_hydro_49)PF17433(Glyco_hydro_49N) | 3 | ASN X 499ILE X 430MET X 423 | None | 0.78A | 2h42C-1ogoX:undetectable | 2h42C-1ogoX:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p4i | ANTIBODY VARIABLEHEAVY CHAIN (Mus musculus) |
PF07686(V-set) | 3 | ASN H 42ILE H 21MET H 93 | None | 0.71A | 2h42C-1p4iH:undetectable | 2h42C-1p4iH:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4p | SHIGA-LIKE TOXINTYPE II A SUBUNIT (Escherichiacoli) |
PF00161(RIP) | 3 | ASN A 201ILE A 174MET A 191 | None | 0.60A | 2h42C-1r4pA:undetectable | 2h42C-1r4pA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v0m | ENDO-1,4-BETA-XYLANASE A (Streptomyceslividans) |
PF00331(Glyco_hydro_10) | 3 | ASN A 170ILE A 199MET A 188 | None | 0.82A | 2h42C-1v0mA:undetectable | 2h42C-1v0mA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6u | ENDO-1,4-BETA-D-XYLANASE (Streptomycesolivaceoviridis) |
PF00331(Glyco_hydro_10)PF00652(Ricin_B_lectin) | 3 | ASN A 170ILE A 199MET A 188 | None | 0.82A | 2h42C-1v6uA:undetectable | 2h42C-1v6uA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6y | ENDO-1,4-BETA-D-XYLANASE ANDENDO-1,4-BETA-XYLANASE B (Cellulomonasfimi;Streptomycesolivaceoviridis) |
PF00331(Glyco_hydro_10) | 3 | ASN A 170ILE A 199MET A 188 | None | 0.82A | 2h42C-1v6yA:undetectable | 2h42C-1v6yA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrq | SARCOSINE OXIDASEALPHA SUBUNIT (Corynebacteriumsp. U-96) |
PF01571(GCV_T)PF08669(GCV_T_C)PF12831(FAD_oxidored)PF13510(Fer2_4) | 3 | ASN A 646ILE A 636MET A 689 | None | 0.83A | 2h42C-1vrqA:undetectable | 2h42C-1vrqA:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xdw | NAD+-DEPENDENT(R)-2-HYDROXYGLUTARATE DEHYDROGENASE (Acidaminococcusfermentans) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 3 | ASN A 146ILE A 201MET A 115 | None | 0.85A | 2h42C-1xdwA:undetectable | 2h42C-1xdwA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xyz | 1,4-BETA-D-XYLAN-XYLANOHYDROLASE (Ruminiclostridiumthermocellum) |
PF00331(Glyco_hydro_10) | 3 | ASN A 687ILE A 715MET A 704 | None | 0.82A | 2h42C-1xyzA:undetectable | 2h42C-1xyzA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yve | ACETOHYDROXY ACIDISOMEROREDUCTASE (Spinaciaoleracea) |
PF01450(IlvC)PF07991(IlvN) | 3 | ASN I 516ILE I 436MET I 433 | None | 0.75A | 2h42C-1yveI:undetectable | 2h42C-1yveI:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cw7 | ENDONUCLEASEPI-PKOII (Thermococcuskodakarensis) |
PF14528(LAGLIDADG_3)PF14890(Intein_splicing) | 3 | ASN A 349ILE A 272MET A 268 | None | 0.82A | 2h42C-2cw7A:undetectable | 2h42C-2cw7A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9g | MITOGEN-ACTIVATEDPROTEIN KINASE FUS3 (Saccharomycescerevisiae) |
PF00069(Pkinase) | 3 | ASN A 142ILE A 145MET A 96 | MG A 600 ( 2.7A)NoneNone | 0.84A | 2h42C-2f9gA:undetectable | 2h42C-2f9gA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fuq | HEPARINASE IIPROTEIN (Pedobacterheparinus) |
PF07940(Hepar_II_III)PF16332(DUF4962) | 3 | ASN A 669ILE A 416MET A 396 | None | 0.85A | 2h42C-2fuqA:undetectable | 2h42C-2fuqA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g02 | NISIN BIOSYNTHESISPROTEIN NISC (Lactococcuslactis) |
PF05147(LANC_like) | 3 | ASN A 362ILE A 324MET A 318 | None | 0.86A | 2h42C-2g02A:undetectable | 2h42C-2g02A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gn1 | THREONINEDEHYDRATASECATABOLIC (Salmonellaenterica) |
PF00291(PALP) | 3 | ASN A 178ILE A 309MET A 30 | None | 0.76A | 2h42C-2gn1A:undetectable | 2h42C-2gn1A:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gvi | CONSERVEDHYPOTHETICAL PROTEIN (Thermoplasmaacidophilum) |
PF02663(FmdE) | 3 | ASN A 105ILE A 151MET A 25 | ACY A 410 ( 3.5A)NoneNone | 0.85A | 2h42C-2gviA:undetectable | 2h42C-2gviA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i7t | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR73 KDA SUBUNIT (Homo sapiens) |
PF00753(Lactamase_B)PF07521(RMMBL)PF10996(Beta-Casp) | 3 | ASN A 450ILE A 59MET A 38 | None | 0.85A | 2h42C-2i7tA:undetectable | 2h42C-2i7tA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lp4 | CHEMOTAXIS PROTEINCHEA (Escherichiacoli) |
PF01627(Hpt)PF09078(CheY-binding) | 3 | ASN A 89ILE A 119MET A 69 | None | 0.83A | 2h42C-2lp4A:undetectable | 2h42C-2lp4A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7q | BIFUNCTIONAL3-DEHYDROQUINATEDEHYDRATASE/SHIKIMATE DEHYDROGENASE (Arabidopsisthaliana) |
PF01487(DHquinase_I)PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 3 | ASN A 134ILE A 142MET A 108 | None | 0.76A | 2h42C-2o7qA:undetectable | 2h42C-2o7qA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o9r | BETA-GLUCOSIDASE B (Paenibacilluspolymyxa) |
PF00232(Glyco_hydro_1) | 3 | ASN A 163ILE A 115MET A 13 | None | 0.74A | 2h42C-2o9rA:undetectable | 2h42C-2o9rA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pgw | MUCONATECYCLOISOMERASE (Sinorhizobiummeliloti) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ASN A 8ILE A 37MET A 113 | None | 0.82A | 2h42C-2pgwA:undetectable | 2h42C-2pgwA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qh5 | MANNOSE-6-PHOSPHATEISOMERASE (Helicobacterpylori) |
PF00483(NTP_transferase) | 3 | ASN A 90ILE A 6MET A 98 | None | 0.84A | 2h42C-2qh5A:undetectable | 2h42C-2qh5A:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yq4 | D-ISOMER SPECIFIC2-HYDROXYACIDDEHYDROGENASE (Lactobacillusdelbrueckii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 3 | ASN A 148ILE A 203MET A 116 | None | 0.80A | 2h42C-2yq4A:undetectable | 2h42C-2yq4A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9e | CHITINASE A (Vibrio harveyi) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 3 | ASN A 34ILE A 28MET A 111 | None | 0.72A | 2h42C-3b9eA:undetectable | 2h42C-3b9eA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3o | PUTATIVETRANSCRIPTIONALREGULATOR, ICIRFAMILY (Acinetobactersp. ADP1) |
no annotation | 3 | ASN A 61ILE A 101MET A 69 | SO4 A 176 ( 4.9A)NoneNone | 0.61A | 2h42C-3d3oA:undetectable | 2h42C-3d3oA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fah | ALDEHYDEOXIDOREDUCTASE (Desulfovibriogigas) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 3 | ASN A 714ILE A 644MET A 672 | None | 0.85A | 2h42C-3fahA:undetectable | 2h42C-3fahA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fr8 | PUTATIVE KETOL-ACIDREDUCTOISOMERASE(OS05G0573700PROTEIN) (Oryza sativa) |
PF01450(IlvC)PF07991(IlvN) | 3 | ASN A 516ILE A 436MET A 433 | None | 0.76A | 2h42C-3fr8A:undetectable | 2h42C-3fr8A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fss | HISTONE CHAPERONERTT106 (Saccharomycescerevisiae) |
PF08512(Rtt106) | 3 | ASN A 120ILE A 200MET A 142 | None | 0.76A | 2h42C-3fssA:undetectable | 2h42C-3fssA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyu | NUCLEAR HORMONERECEPTOR OF THESTEROID/THYROIDHORMONE RECEPTORSSUPERFAMILY (Strongyloidesstercoralis) |
PF00104(Hormone_recep) | 3 | ASN A 557ILE A 621MET A 625 | NoneDL7 A 200 ( 4.5A)DL7 A 200 ( 4.7A) | 0.71A | 2h42C-3gyuA:undetectable | 2h42C-3gyuA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hz7 | UNCHARACTERIZEDPROTEIN (Desulfitobacteriumhafniense) |
PF01206(TusA) | 3 | ASN A 44ILE A 70MET A 52 | SX A 101 ( 4.7A)NoneNone | 0.84A | 2h42C-3hz7A:undetectable | 2h42C-3hz7A:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibj | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I)PF01590(GAF)PF13185(GAF_2) | 3 | ASN A 599ILE A 596MET A 622 | None | 0.81A | 2h42C-3ibjA:38.5 | 2h42C-3ibjA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ioy | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Novosphingobiumaromaticivorans) |
PF00106(adh_short) | 3 | ASN A 91ILE A 254MET A 247 | None | 0.78A | 2h42C-3ioyA:undetectable | 2h42C-3ioyA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iz3 | STRUCTURAL PROTEINVP1 (Cypovirus 1) |
no annotation | 3 | ASN B 715ILE B 409MET B 413 | None | 0.69A | 2h42C-3iz3B:undetectable | 2h42C-3iz3B:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k13 | 5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINEMETHYLTRANSFERASE (Bacteroidesthetaiotaomicron) |
PF00809(Pterin_bind) | 3 | ASN A 521ILE A 540MET A 589 | None | 0.68A | 2h42C-3k13A:undetectable | 2h42C-3k13A:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l4e | UNCHARACTERIZEDPEPTIDASE LMO0363 (Listeriamonocytogenes) |
PF03575(Peptidase_S51) | 3 | ASN A 162ILE A 173MET A 135 | None | 0.84A | 2h42C-3l4eA:undetectable | 2h42C-3l4eA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lmk | METABOTROPICGLUTAMATE RECEPTOR 5 (Homo sapiens) |
PF01094(ANF_receptor) | 3 | ASN A 88ILE A 35MET A 429 | None | 0.66A | 2h42C-3lmkA:undetectable | 2h42C-3lmkA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfe | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Legionellapneumophila) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 3 | ASN A 51ILE A 158MET A 81 | None | 0.72A | 2h42C-3pfeA:undetectable | 2h42C-3pfeA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3v | PHOSPHOGLYCERATEKINASE (Campylobacterjejuni) |
PF00162(PGK) | 3 | ASN A 320ILE A 317MET A 369 | None | 0.85A | 2h42C-3q3vA:undetectable | 2h42C-3q3vA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qcw | NEUREXIN-1-ALPHA (Bos taurus) |
PF00008(EGF)PF02210(Laminin_G_2) | 3 | ASN A 980ILE A1000MET A 934 | None | 0.84A | 2h42C-3qcwA:undetectable | 2h42C-3qcwA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqr | NON-LEGUMEHEMOGLOBIN (Parasponiaandersonii) |
PF00042(Globin) | 3 | ASN A 28ILE A 126MET A 133 | None | 0.65A | 2h42C-3qqrA:undetectable | 2h42C-3qqrA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qzy | BACULOVIRUSSULFHYDRYL OXIDASEAC92 (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF05214(Baculo_p33) | 3 | ASN A 226ILE A 169MET A 113 | FAD A 334 (-2.9A)NoneFAD A 334 ( 3.7A) | 0.68A | 2h42C-3qzyA:undetectable | 2h42C-3qzyA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3stj | PROTEASE DEGQ (Escherichiacoli) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 3 | ASN A 202ILE A 113MET A 223 | None | 0.79A | 2h42C-3stjA:undetectable | 2h42C-3stjA:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tl1 | POLYKETIDE CYCLASE (Streptomycescoelicolor) |
PF03364(Polyketide_cyc) | 3 | ASN A 20ILE A 11MET A 106 | None | 0.74A | 2h42C-3tl1A:undetectable | 2h42C-3tl1A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vas | PUTATIVE ADENOSINEKINASE (Schistosomamansoni) |
PF00294(PfkB) | 3 | ASN A 172ILE A 166MET A 212 | None | 0.84A | 2h42C-3vasA:undetectable | 2h42C-3vasA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vfd | SPASTIN (Homo sapiens) |
PF00004(AAA)PF09336(Vps4_C) | 3 | ASN A 580ILE A 562MET A 573 | None | 0.76A | 2h42C-3vfdA:undetectable | 2h42C-3vfdA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vxc | PUTATIVESUGAR-BINDINGLIPOPROTEIN (Streptomycesthermoviolaceus) |
PF01547(SBP_bac_1) | 3 | ASN A 327ILE A 98MET A 74 | BXP A 601 (-2.9A)NoneNone | 0.70A | 2h42C-3vxcA:undetectable | 2h42C-3vxcA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wky | PROPHENOLOXIDASE B (Marsupenaeusjaponicus) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 3 | ASN A 492ILE A 489MET A 656 | None | 0.82A | 2h42C-3wkyA:undetectable | 2h42C-3wkyA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wst | PROTEIN ARGININEN-METHYLTRANSFERASE7 (Caenorhabditiselegans) |
PF13649(Methyltransf_25) | 3 | ASN A 638ILE A 548MET A 577 | None | 0.82A | 2h42C-3wstA:undetectable | 2h42C-3wstA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wuf | ENDO-1,4-BETA-XYLANASE A (Streptomycessp.) |
PF00331(Glyco_hydro_10) | 3 | ASN A 207ILE A 235MET A 224 | None | 0.85A | 2h42C-3wufA:undetectable | 2h42C-3wufA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a69 | HISTONE DEACETYLASE3, (Homo sapiens) |
PF00850(Hist_deacetyl) | 3 | ASN A 128ILE A 125MET A 45 | None | 0.79A | 2h42C-4a69A:undetectable | 2h42C-4a69A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a8j | ELONGATOR COMPLEXPROTEIN 5 (Saccharomycescerevisiae) |
PF10483(Elong_Iki1) | 3 | ASN B 110ILE B 58MET B 131 | None | 0.75A | 2h42C-4a8jB:undetectable | 2h42C-4a8jB:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bla | MALTOSE-BINDINGPERIPLASMIC PROTEIN,SUPPRESSOR OF FUSEDHOMOLOG (Escherichiacoli;Homo sapiens) |
PF05076(SUFU)PF12470(SUFU_C)PF13416(SBP_bac_8) | 3 | ASN A 639ILE A 671MET A 669 | None | 0.80A | 2h42C-4blaA:undetectable | 2h42C-4blaA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ccz | METHIONINE SYNTHASE (Homo sapiens) |
PF00809(Pterin_bind)PF02574(S-methyl_trans) | 3 | ASN A 539ILE A 558MET A 607 | None | 0.74A | 2h42C-4cczA:undetectable | 2h42C-4cczA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eco | UNCHARACTERIZEDPROTEIN (Bacteroideseggerthii) |
no annotation | 3 | ASN A 627ILE A 577MET A 411 | None | 0.77A | 2h42C-4ecoA:undetectable | 2h42C-4ecoA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ejs | ELONGATOR COMPLEXPROTEIN 5 (Saccharomycescerevisiae) |
PF10483(Elong_Iki1) | 3 | ASN B 110ILE B 58MET B 131 | None | 0.72A | 2h42C-4ejsB:undetectable | 2h42C-4ejsB:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4elj | RETINOBLASTOMA-ASSOCIATED PROTEIN (Homo sapiens) |
PF01857(RB_B)PF01858(RB_A)PF11934(DUF3452) | 3 | ASN A 519ILE A 422MET A 484 | None | 0.72A | 2h42C-4eljA:undetectable | 2h42C-4eljA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emk | U6 SNRNA-ASSOCIATEDSM-LIKE PROTEIN LSM5 (Schizosaccharomycespombe) |
PF01423(LSM) | 3 | ASN A 18ILE A 42MET A 63 | None | 0.82A | 2h42C-4emkA:undetectable | 2h42C-4emkA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1k | THROMBOSPONDINRELATED ANONYMOUSPROTEIN (Plasmodiumfalciparum) |
PF00092(VWA) | 3 | ASN A 125ILE A 59MET A 53 | None | 0.85A | 2h42C-4f1kA:undetectable | 2h42C-4f1kA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fye | SIDF, INHIBITOR OFGROWTH FAMILY,MEMBER 3 (Legionellapneumophila) |
no annotation | 3 | ASN A 662ILE A 201MET A 248 | None | 0.83A | 2h42C-4fyeA:undetectable | 2h42C-4fyeA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga6 | PUTATIVE THYMIDINEPHOSPHORYLASE (Thermococcuskodakarensis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 3 | ASN A 172ILE A 197MET A 261 | NoneAMP A 601 (-4.2A)AMP A 601 (-4.2A) | 0.66A | 2h42C-4ga6A:undetectable | 2h42C-4ga6A:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gps | KLLA0E02245P (Kluyveromyceslactis) |
no annotation | 3 | ASN A 284ILE A 333MET A 294 | None | 0.67A | 2h42C-4gpsA:undetectable | 2h42C-4gpsA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ng4 | PHOSPHOGLYCERATEKINASE (Coxiellaburnetii) |
PF00162(PGK) | 3 | ASN A 315ILE A 312MET A 364 | ADP A 402 (-3.1A)NoneNone | 0.79A | 2h42C-4ng4A:undetectable | 2h42C-4ng4A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nqy | ISOPROPYLMALATE/CITRAMALATE ISOMERASELARGE SUBUNIT (Methanocaldococcusjannaschii) |
PF00330(Aconitase) | 3 | ASN A 163ILE A 227MET A 205 | None | 0.71A | 2h42C-4nqyA:undetectable | 2h42C-4nqyA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4okd | ISOAMYLASE (Chlamydomonasreinhardtii) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 3 | ASN A 551ILE A 261MET A 256 | None | 0.78A | 2h42C-4okdA:undetectable | 2h42C-4okdA:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q38 | PUTATIVEUNCHARACTERIZEDPROTEIN TCP24 (Actinoplanesteichomyceticus) |
no annotation | 3 | ASN A 286ILE A 149MET A 161 | NoneNoneTEC A 404 (-4.3A) | 0.62A | 2h42C-4q38A:undetectable | 2h42C-4q38A:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9v | SIALYLTRANSFERASE0160 (Photobacteriumdamselae) |
PF11477(PM0188) | 3 | ASN A 204ILE A 209MET A 177 | None | 0.80A | 2h42C-4r9vA:undetectable | 2h42C-4r9vA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rjk | ACETOLACTATESYNTHASE (Bacillussubtilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 3 | ASN A 386ILE A 380MET A 405 | None | 0.77A | 2h42C-4rjkA:undetectable | 2h42C-4rjkA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rzi | 3-KETOACYL-ACYLCARRIER PROTEINREDUCTASE (Synechocystissp. PCC 6803) |
no annotation | 3 | ASN B 82ILE B 129MET B 157 | None | 0.83A | 2h42C-4rziB:undetectable | 2h42C-4rziB:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uei | STEROL CARRIERPROTEIN2/3-OXOACYL-COATHIOLASE (Helicoverpaarmigera) |
PF02036(SCP2) | 3 | ASN A 80ILE A 68MET A 29 | None | 0.58A | 2h42C-4ueiA:undetectable | 2h42C-4ueiA:16.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ye5 | PEPTIDOGLYCANSYNTHETASEPENICILLIN-BINDINGPROTEIN 3 (Bifidobacteriumadolescentis) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 3 | ASN A 409ILE A 289MET A 443 | None | 0.79A | 2h42C-4ye5A:undetectable | 2h42C-4ye5A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yhw | U4/U6 SMALL NUCLEARRIBONUCLEOPROTEINPRP3 (Saccharomycescerevisiae) |
PF06544(DUF1115) | 3 | ASN A 346ILE A 380MET A 442 | NoneNone G E 86 ( 3.8A) | 0.84A | 2h42C-4yhwA:undetectable | 2h42C-4yhwA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yte | H(2)-FORMINGMETHYLENETETRAHYDROMETHANOPTERINDEHYDROGENASE-RELATED PROTEIN MJ0715 (Methanocaldococcusjannaschii) |
no annotation | 3 | ASN A 176ILE A 84MET A 143 | None | 0.62A | 2h42C-4yteA:undetectable | 2h42C-4yteA:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bqd | T-BOX TRANSCRIPTIONFACTOR TBX5 (Homo sapiens) |
PF00907(T-box) | 3 | ASN A 230ILE A 222MET A 74 | None | 0.57A | 2h42C-5bqdA:undetectable | 2h42C-5bqdA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ci5 | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Pseudothermotogalettingae) |
PF13416(SBP_bac_8) | 3 | ASN A 151ILE A 169MET A 258 | None | 0.71A | 2h42C-5ci5A:undetectable | 2h42C-5ci5A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5doo | PROTEIN LYSINEMETHYLTRANSFERASE 2 (Rickettsiatyphi) |
PF10119(MethyTransf_Reg)PF13847(Methyltransf_31) | 3 | ASN A 304ILE A 276MET A 257 | None | 0.79A | 2h42C-5dooA:undetectable | 2h42C-5dooA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dpd | PROTEIN LYSINEMETHYLTRANSFERASE 1 (Rickettsiaprowazekii) |
PF10119(MethyTransf_Reg)PF13847(Methyltransf_31) | 3 | ASN A 332ILE A 304MET A 285 | None | 0.76A | 2h42C-5dpdA:undetectable | 2h42C-5dpdA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e1x | TRANSCRIPTIONALREGULATOR, MARRFAMILY (Dehalococcoidesmccartyi) |
PF12802(MarR_2) | 3 | ASN A 16ILE A 24MET A 123 | None | 0.77A | 2h42C-5e1xA:undetectable | 2h42C-5e1xA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ee4 | HPUA (Kingelladenitrificans) |
PF16960(HpuA) | 3 | ASN A 297ILE A 225MET A 237 | None | 0.72A | 2h42C-5ee4A:undetectable | 2h42C-5ee4A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hhl | RETRON-TYPE REVERSETRANSCRIPTASE ([Eubacterium]rectale) |
PF00078(RVT_1) | 3 | ASN A 239ILE A 140MET A 259 | None | 0.81A | 2h42C-5hhlA:undetectable | 2h42C-5hhlA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzh | RAS-RELATED C3BOTULINUM TOXINSUBSTRATE1,NPH1-1,RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 3 | ASN A 185ILE A 64MET A 146 | None | 0.85A | 2h42C-5hzhA:undetectable | 2h42C-5hzhA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irr | SEPTIN-LIKE PROTEIN (Chlamydomonasreinhardtii) |
PF00735(Septin) | 3 | ASN A 285ILE A 297MET A 248 | None | 0.80A | 2h42C-5irrA:undetectable | 2h42C-5irrA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j5u | RAGB/SUSD DOMAINPROTEIN (Flavobacteriumjohnsoniae) |
PF12771(SusD-like_2) | 3 | ASN A 120ILE A 108MET A 128 | None | 0.80A | 2h42C-5j5uA:undetectable | 2h42C-5j5uA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jzb | 4,5:9,10-DISECO-3-HYDROXY-5,9,17-TRIOXOANDROSTA-1(10),2-DIENE-4-OATE HYDROLASE (Mycobacteriumtuberculosis) |
PF12697(Abhydrolase_6) | 3 | ASN A 169ILE A 184MET A 177 | NoneNone6OT A 301 ( 4.9A) | 0.82A | 2h42C-5jzbA:undetectable | 2h42C-5jzbA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8b | 8-AMINO-3,8-DIDEOXY-ALPHA-D-MANNO-OCTULOSONATE TRANSAMINASE (Shewanellaoneidensis) |
PF01041(DegT_DnrJ_EryC1) | 3 | ASN A 311ILE A 386MET A 269 | None | 0.75A | 2h42C-5k8bA:undetectable | 2h42C-5k8bA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0k | BETA-XYLANASE (Cellulomonasflavigena) |
no annotation | 3 | ASN A 170ILE A 198MET A 187 | None | 0.77A | 2h42C-5m0kA:undetectable | 2h42C-5m0kA:11.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpm | SARCOPLASMIC/ENDOPLASMIC RETICULUMCALCIUM ATPASE 2 (Sus scrofa) |
no annotation | 3 | ASN A 380ILE A 384MET A 452 | None | 0.83A | 2h42C-5mpmA:undetectable | 2h42C-5mpmA:14.15 |