SIMILAR PATTERNS OF AMINO ACIDS FOR 2GJ5_A_VD3A164

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1boo PROTEIN (N-4
CYTOSINE-SPECIFIC
METHYLTRANSFERASE
PVU II)


(Proteus
vulgaris)
PF01555
(N6_N4_Mtase)
4 ASP A  74
LEU A  77
MET A 119
ARG A 118
None
1.37A 2gj5A-1booA:
undetectable
2gj5A-1booA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brw PROTEIN (PYRIMIDINE
NUCLEOSIDE
PHOSPHORYLASE)


(Geobacillus
stearothermophilus)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
4 ASP A 212
LEU A 211
LYS A 210
ARG A 215
None
1.28A 2gj5A-1brwA:
0.0
2gj5A-1brwA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgp ARISTOLOCHENE
SYNTHASE


(Penicillium
roqueforti)
no annotation 4 ASP A 245
LEU A 287
LYS A 284
MET A 290
FOH  A 401 (-3.5A)
None
None
None
1.38A 2gj5A-1dgpA:
undetectable
2gj5A-1dgpA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e08 CYTOCHROME C553

(Desulfovibrio
vulgaris)
PF00034
(Cytochrom_C)
4 ASP E  66
LEU E  69
LYS E  70
MET E  41
None
None
None
HEM  E  80 (-3.6A)
1.29A 2gj5A-1e08E:
undetectable
2gj5A-1e08E:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f59 IMPORTIN BETA-1

(Homo sapiens)
PF03810
(IBN_N)
PF13513
(HEAT_EZ)
4 ASP A 230
LEU A 192
LYS A 191
ARG A 232
None
1.21A 2gj5A-1f59A:
undetectable
2gj5A-1f59A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq8 PECTINESTERASE

(Daucus carota)
PF01095
(Pectinesterase)
4 ASP A 100
LEU A  62
MET A  60
ARG A  99
None
1.45A 2gj5A-1gq8A:
undetectable
2gj5A-1gq8A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hxj BETA-GLUCOSIDASE

(Zea mays)
PF00232
(Glyco_hydro_1)
4 ASP A  78
LEU A  81
MET A 483
ARG A 481
None
1.17A 2gj5A-1hxjA:
0.0
2gj5A-1hxjA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nl4 PROTEIN
FARNESYLTRANSFERASE
ALPHA SUBUNIT


(Rattus
norvegicus)
PF01239
(PPTA)
4 ASP A 224
LEU A 227
LYS A 228
ARG A 240
None
1.28A 2gj5A-1nl4A:
undetectable
2gj5A-1nl4A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA


(Bacillus
subtilis)
PF01522
(Polysacc_deac_1)
4 ASP A  86
LEU A  85
MET A 114
ARG A 113
None
1.28A 2gj5A-1ny1A:
0.0
2gj5A-1ny1A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pto PERTUSSIS TOXIN
PERTUSSIS TOXIN
(SUBUNIT S5)


(Bordetella
pertussis)
PF02918
(Pertussis_S2S3)
PF03440
(APT)
PF09276
(Pertus-S5-tox)
4 ASP F  54
LEU F  57
MET B 152
ARG B 148
None
1.32A 2gj5A-1ptoF:
0.9
2gj5A-1ptoF:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)


(Homo sapiens)
PF03810
(IBN_N)
PF13513
(HEAT_EZ)
4 ASP A 230
LEU A 192
LYS A 191
ARG A 232
None
1.35A 2gj5A-1qgrA:
undetectable
2gj5A-1qgrA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sjp 60 KDA CHAPERONIN 2

(Mycobacterium
tuberculosis)
PF00118
(Cpn60_TCP1)
4 ASP A 288
LEU A 369
LYS A 368
ARG A 342
None
1.35A 2gj5A-1sjpA:
0.0
2gj5A-1sjpA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1to3 PUTATIVE ALDOLASE
YIHT


(Salmonella
enterica)
PF01791
(DeoC)
4 ASP A  42
LEU A  45
MET A  27
ARG A  28
None
1.39A 2gj5A-1to3A:
0.0
2gj5A-1to3A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6t HYPOTHETICAL UPF0271
PROTEIN PH0986


(Pyrococcus
horikoshii)
PF03746
(LamB_YcsF)
4 ASP A 214
LEU A 215
LYS A 216
MET A 199
None
0.99A 2gj5A-1v6tA:
undetectable
2gj5A-1v6tA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vf8 SECRETORY PROTEIN

(Mus musculus)
PF00704
(Glyco_hydro_18)
4 ASP A 184
LEU A 159
MET A 141
ARG A 156
None
1.38A 2gj5A-1vf8A:
undetectable
2gj5A-1vf8A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygp YEAST GLYCOGEN
PHOSPHORYLASE


(Saccharomyces
cerevisiae)
PF00343
(Phosphorylase)
4 ASP A  96
LEU A  99
MET A 102
ARG A 113
None
1.39A 2gj5A-1ygpA:
undetectable
2gj5A-1ygpA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bsk MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM10
MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM9 A


(Homo sapiens)
PF02953
(zf-Tim10_DDP)
4 ASP B  52
LEU B  51
MET A  59
ARG A  62
None
1.38A 2gj5A-2bskB:
undetectable
2gj5A-2bskB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxr HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CYNR


(Escherichia
coli)
PF03466
(LysR_substrate)
4 ASP A 142
LEU A 141
MET A 135
ARG A  94
None
1.31A 2gj5A-2hxrA:
undetectable
2gj5A-2hxrA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j13 POLYSACCHARIDE
DEACETYLASE


(Bacillus
anthracis)
PF01522
(Polysacc_deac_1)
4 ASP A  65
LEU A  64
MET A  93
ARG A  92
None
1.29A 2gj5A-2j13A:
undetectable
2gj5A-2j13A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jfe CYTOSOLIC
BETA-GLUCOSIDASE


(Homo sapiens)
PF00232
(Glyco_hydro_1)
4 ASP X 105
LEU X 108
LYS X 109
ARG X 156
None
1.31A 2gj5A-2jfeX:
undetectable
2gj5A-2jfeX:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o36 THIMET
OLIGOPEPTIDASE


(Homo sapiens)
PF01432
(Peptidase_M3)
4 ASP A 102
LEU A 105
LYS A 104
ARG A  79
None
1.43A 2gj5A-2o36A:
undetectable
2gj5A-2o36A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qna IMPORTIN SUBUNIT
BETA-1


(Homo sapiens)
PF13513
(HEAT_EZ)
4 ASP A 230
LEU A 192
LYS A 191
ARG A 232
None
1.37A 2gj5A-2qnaA:
undetectable
2gj5A-2qnaA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8u CHITIN DEACETYLASE

(Aspergillus
nidulans)
PF01522
(Polysacc_deac_1)
4 ASP A  59
LEU A  58
MET A  87
ARG A  86
None
1.18A 2gj5A-2y8uA:
undetectable
2gj5A-2y8uA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzk OROTATE
PHOSPHORIBOSYLTRANSF
ERASE


(Aeropyrum
pernix)
PF00156
(Pribosyltran)
4 ASP A  46
LEU A  45
MET A  75
ARG A  79
None
1.45A 2gj5A-2yzkA:
undetectable
2gj5A-2yzkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3adp LAMBDA-CRYSTALLIN

(Oryctolagus
cuniculus)
PF00725
(3HCDH)
PF02737
(3HCDH_N)
4 ASP A 303
LEU A 306
LYS A 307
ARG A 302
None
1.42A 2gj5A-3adpA:
undetectable
2gj5A-3adpA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF


(Escherichia
coli)
PF13417
(GST_N_3)
PF14834
(GST_C_4)
4 ASP A 183
LEU A 178
MET A 174
ARG A 120
None
1.33A 2gj5A-3bbyA:
undetectable
2gj5A-3bbyA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bq8 SENSOR PROTEIN PHOQ

(Escherichia
coli)
PF08918
(PhoQ_Sensor)
4 ASP A  90
LEU A 173
LYS A 172
MET A 170
None
1.30A 2gj5A-3bq8A:
undetectable
2gj5A-3bq8A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czq PUTATIVE
POLYPHOSPHATE KINASE
2


(Sinorhizobium
meliloti)
PF03976
(PPK2)
4 ASP A 238
LEU A 241
LYS A 242
ARG A 237
None
1.38A 2gj5A-3czqA:
undetectable
2gj5A-3czqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epy ACYL-COA-BINDING
DOMAIN-CONTAINING
PROTEIN 7


(Homo sapiens)
PF00887
(ACBP)
4 ASP A  23
LEU A  26
LYS A  27
ARG A  20
None
PLM  A 101 ( 4.2A)
None
None
1.21A 2gj5A-3epyA:
undetectable
2gj5A-3epyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hps 2-ISOPROPYLMALATE
SYNTHASE


(Mycobacterium
tuberculosis)
PF00682
(HMGL-like)
PF08502
(LeuA_dimer)
4 ASP A 306
LEU A 282
MET A 270
ARG A 277
None
1.35A 2gj5A-3hpsA:
undetectable
2gj5A-3hpsA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpx 2-ISOPROPYLMALATE
SYNTHASE


(Mycobacterium
tuberculosis)
PF00682
(HMGL-like)
4 ASP A 306
LEU A 282
MET A 270
ARG A 277
None
1.35A 2gj5A-3hpxA:
undetectable
2gj5A-3hpxA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hv0 TRYPTOPHANYL-TRNA
SYNTHETASE


(Cryptosporidium
parvum)
PF00579
(tRNA-synt_1b)
4 ASP A 267
LEU A 266
MET A 239
ARG A 238
None
1.42A 2gj5A-3hv0A:
undetectable
2gj5A-3hv0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4g SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN BF1063


(Bacteroides
fragilis)
PF07980
(SusD_RagB)
PF14322
(SusD-like_3)
4 ASP A 304
LEU A 305
MET A 468
ARG A 463
EDO  A   4 (-3.3A)
None
None
None
1.46A 2gj5A-3i4gA:
undetectable
2gj5A-3i4gA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ism CG4930

(Drosophila
melanogaster)
PF08785
(Ku_PK_bind)
4 ASP C 116
LEU C 119
LYS C 120
ARG C 115
None
1.28A 2gj5A-3ismC:
undetectable
2gj5A-3ismC:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1z HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN 3


(Homo sapiens)
PF13419
(HAD_2)
4 ASP A 242
LEU A 241
MET A   7
ARG A 127
None
1.25A 2gj5A-3k1zA:
undetectable
2gj5A-3k1zA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kb6 D-LACTATE
DEHYDROGENASE


(Aquifex
aeolicus)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 ASP A 177
LEU A 178
LYS A 181
ARG A 175
None
None
None
PEG  A 701 ( 4.4A)
1.43A 2gj5A-3kb6A:
undetectable
2gj5A-3kb6A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kv6 JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 1D


(Homo sapiens)
PF00628
(PHD)
PF02373
(JmjC)
4 ASP A 308
LEU A 311
MET A 384
ARG A 380
None
1.20A 2gj5A-3kv6A:
undetectable
2gj5A-3kv6A:
15.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kza BETA-LACTOGLOBULIN

(Bos taurus;
Equus caballus)
PF00061
(Lipocalin)
4 ASP A 137
LEU A 140
MET A 145
ARG A 148
None
0.97A 2gj5A-3kzaA:
25.6
2gj5A-3kzaA:
81.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lsc TRIAZINE HYDROLASE

(Paenarthrobacter
aurescens)
PF01979
(Amidohydro_1)
4 ASP A  41
LEU A   3
LYS A   1
ARG A   5
None
1.07A 2gj5A-3lscA:
undetectable
2gj5A-3lscA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzn GLUCARATE
DEHYDRATASE


(Chromohalobacter
salexigens)
PF13378
(MR_MLE_C)
4 ASP A 239
LEU A 238
LYS A 237
ARG A 277
None
1.06A 2gj5A-3mznA:
undetectable
2gj5A-3mznA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnq N-TERMINAL DOMAIN OF
MOLONEY MURINE
LEUKEMIA VIRUS
INTEGRASE


(Murine leukemia
virus)
PF16721
(zf-H3C2)
4 ASP A  85
LEU A  88
MET A  68
ARG A  84
None
1.42A 2gj5A-3nnqA:
undetectable
2gj5A-3nnqA:
18.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ph5 BETA-LACTOGLOBULIN

(Bos taurus)
PF00061
(Lipocalin)
4 ASP A 153
LEU A 156
LYS A 157
MET A 161
None
0.86A 2gj5A-3ph5A:
29.2
2gj5A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ph5 BETA-LACTOGLOBULIN

(Bos taurus)
PF00061
(Lipocalin)
4 ASP A 153
LEU A 156
MET A 161
ARG A 164
None
0.92A 2gj5A-3ph5A:
29.2
2gj5A-3ph5A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppx VON WILLEBRAND
FACTOR


(Homo sapiens)
PF00092
(VWA)
4 ASP A1663
LEU A1666
MET A1528
ARG A1527
None
1.33A 2gj5A-3ppxA:
undetectable
2gj5A-3ppxA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r3j GLUTAMATE
DEHYDROGENASE


(Plasmodium
falciparum)
PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N)
4 ASP A 461
LEU A 464
LYS A 463
MET A 468
None
1.01A 2gj5A-3r3jA:
undetectable
2gj5A-3r3jA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)


(Bacillus cereus)
PF01497
(Peripla_BP_2)
4 ASP A 274
LEU A 273
MET A 143
ARG A 142
None
1.27A 2gj5A-3tnyA:
undetectable
2gj5A-3tnyA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u78 LYSINE-SPECIFIC
DEMETHYLASE 7


(Homo sapiens)
PF02373
(JmjC)
4 ASP A 308
LEU A 311
MET A 384
ARG A 380
None
1.15A 2gj5A-3u78A:
undetectable
2gj5A-3u78A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u8p CYTOCHROME B562
INTEGRAL FUSION WITH
ENHANCED GREEN
FLUORESCENT PROTEIN


(Aequorea
victoria;
Escherichia
coli)
PF01353
(GFP)
PF07361
(Cytochrom_B562)
4 ASP A 115
LEU A 118
LYS A 119
ARG A  76
None
1.27A 2gj5A-3u8pA:
undetectable
2gj5A-3u8pA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu9 CHROMOSOME
SEGREGATION IN
MEIOSIS PROTEIN 2


(Saccharomyces
cerevisiae)
PF16834
(CSM2)
4 ASP B 141
LEU B 144
LYS B 145
ARG B 140
None
1.37A 2gj5A-3vu9B:
undetectable
2gj5A-3vu9B:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3whj PROBABLE 26S
PROTEASOME
REGULATORY SUBUNIT
P27


(Saccharomyces
cerevisiae)
no annotation 4 ASP A  40
LEU A  37
LYS A  38
ARG A  22
None
None
CD  A 205 ( 2.3A)
None
1.43A 2gj5A-3whjA:
undetectable
2gj5A-3whjA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zf8 MANNAN POLYMERASE
COMPLEXES SUBUNIT
MNN9


(Saccharomyces
cerevisiae)
PF03452
(Anp1)
4 ASP A 157
LEU A 160
LYS A 161
ARG A 186
None
1.26A 2gj5A-3zf8A:
undetectable
2gj5A-3zf8A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4are COLLAGENASE G

(Hathewaya
histolytica)
PF01752
(Peptidase_M9)
PF08453
(Peptidase_M9_N)
4 ASP A 678
LEU A 681
LYS A 682
ARG A 437
None
1.18A 2gj5A-4areA:
undetectable
2gj5A-4areA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buc UDP-N-ACETYLMURAMOYL
ALANINE--D-GLUTAMATE
LIGASE


(Thermotoga
maritima)
PF08245
(Mur_ligase_M)
4 ASP A 213
LEU A 216
LYS A 217
ARG A 238
None
1.02A 2gj5A-4bucA:
undetectable
2gj5A-4bucA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czx PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2


(Neurospora
crassa)
no annotation 4 ASP A 200
LEU A 228
MET A 231
ARG A 160
None
1.23A 2gj5A-4czxA:
undetectable
2gj5A-4czxA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4did INOSITOL PHOSPHATE
PHOSPHATASE SOPB


(Salmonella
enterica)
PF05925
(IpgD)
4 ASP B  95
LEU B  91
LYS B  93
ARG B 138
None
1.40A 2gj5A-4didB:
undetectable
2gj5A-4didB:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE


(Pseudomonas
putida)
PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N)
4 ASP A 394
LEU A 395
MET A 384
ARG A 325
None
1.46A 2gj5A-4dyjA:
undetectable
2gj5A-4dyjA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnm E3 ALPHA-ESTERASE-7
CARBOXYLESTERASE


(Lucilia cuprina)
PF00135
(COesterase)
4 LEU A 545
LYS A 546
MET A 521
ARG A 499
None
1.39A 2gj5A-4fnmA:
1.9
2gj5A-4fnmA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fo0 ACTIN-RELATED
PROTEIN 8


(Homo sapiens)
PF00022
(Actin)
4 ASP A 383
LEU A 386
LYS A 385
MET A 390
None
None
GOL  A 707 (-2.7A)
None
1.40A 2gj5A-4fo0A:
undetectable
2gj5A-4fo0A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfh DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae)
PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF02518
(HATPase_c)
PF16898
(TOPRIM_C)
4 ASP A 621
LEU A 624
LYS A 625
MET A 522
None
1.39A 2gj5A-4gfhA:
undetectable
2gj5A-4gfhA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hy3 PHOSPHOGLYCERATE
OXIDOREDUCTASE


(Rhizobium etli)
PF02826
(2-Hacid_dh_C)
4 ASP A  49
LEU A  52
MET A  72
ARG A  71
None
1.45A 2gj5A-4hy3A:
undetectable
2gj5A-4hy3A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbb PUTATIVE GLUTATHIONE
S-TRANSFERASE


(Klebsiella
pneumoniae)
PF13417
(GST_N_3)
PF14834
(GST_C_4)
4 ASP A 183
LEU A 178
MET A 174
ARG A 120
None
1.31A 2gj5A-4jbbA:
undetectable
2gj5A-4jbbA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kbr GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1


(Mus musculus)
PF08718
(GLTP)
4 ASP A  30
LEU A  29
MET A  64
ARG A  68
None
1.31A 2gj5A-4kbrA:
undetectable
2gj5A-4kbrA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lb0 UNCHARACTERIZED
PROTEIN


(Agrobacterium
vitis)
PF05544
(Pro_racemase)
4 ASP A 169
LEU A 179
MET A 229
ARG A 231
None
1.14A 2gj5A-4lb0A:
undetectable
2gj5A-4lb0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n4w CYTOCHROME
B(562),SMOOTHENED
HOMOLOG


(Homo sapiens;
Shigella
flexneri)
PF01534
(Frizzled)
PF07361
(Cytochrom_B562)
4 ASP A  73
LEU A  76
LYS A  77
ARG A  34
None
1.04A 2gj5A-4n4wA:
undetectable
2gj5A-4n4wA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ntj P2Y PURINOCEPTOR
12,SOLUBLE
CYTOCHROME B562,P2Y
PURINOCEPTOR 12


(Escherichia
coli;
Homo sapiens)
PF00001
(7tm_1)
PF07361
(Cytochrom_B562)
4 ASP A1073
LEU A1076
LYS A1077
ARG A1034
None
1.33A 2gj5A-4ntjA:
undetectable
2gj5A-4ntjA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzg INTEGRASE P46

(Murine leukemia
virus)
PF16721
(zf-H3C2)
4 ASP A  85
LEU A  88
LYS A  89
MET A  68
None
1.43A 2gj5A-4nzgA:
undetectable
2gj5A-4nzgA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzg INTEGRASE P46

(Murine leukemia
virus)
PF16721
(zf-H3C2)
4 ASP A  85
LEU A  88
MET A  68
ARG A  84
None
1.41A 2gj5A-4nzgA:
undetectable
2gj5A-4nzgA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4or2 SOLUBLE CYTOCHROME
B562, METABOTROPIC
GLUTAMATE RECEPTOR 1


(Escherichia
coli;
Homo sapiens)
PF00003
(7tm_3)
PF07361
(Cytochrom_B562)
4 ASP A1073
LEU A1076
LYS A1077
ARG A1034
None
1.38A 2gj5A-4or2A:
undetectable
2gj5A-4or2A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6q MSX2-INTERACTING
PROTEIN


(Homo sapiens)
PF00076
(RRM_1)
4 ASP A 348
LEU A 351
LYS A 352
ARG A 377
None
1.41A 2gj5A-4p6qA:
undetectable
2gj5A-4p6qA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2h PROLINE RACEMASE
PROTEIN


(Agrobacterium
tumefaciens)
PF05544
(Pro_racemase)
4 ASP A 169
LEU A 179
MET A 229
ARG A 231
None
None
CSO  A 255 ( 4.0A)
None
1.15A 2gj5A-4q2hA:
undetectable
2gj5A-4q2hA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uds MBDR REGULATOR

(Azoarcus sp.
CIB)
PF00440
(TetR_N)
4 ASP A  26
LEU A  27
MET A  40
ARG A  44
None
1.27A 2gj5A-4udsA:
undetectable
2gj5A-4udsA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6p RESISTANCE PROTEIN
PIKP-1


(Oryza sativa)
no annotation 4 LEU A 221
LYS A 228
MET A 207
ARG A 203
None
1.31A 2gj5A-5a6pA:
undetectable
2gj5A-5a6pA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bqs 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3


(Streptococcus
pneumoniae)
PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III)
4 ASP A 253
LEU A 256
MET A 259
ARG A 267
None
1.39A 2gj5A-5bqsA:
undetectable
2gj5A-5bqsA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cg0 BETA-GLUCOSIDASE

(Spodoptera
frugiperda)
PF00232
(Glyco_hydro_1)
4 ASP A 127
LEU A 130
LYS A 131
ARG A 178
None
1.11A 2gj5A-5cg0A:
undetectable
2gj5A-5cg0A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5da0 SULPHATE TRANSPORTER

(Deinococcus
geothermalis)
PF00916
(Sulfate_transp)
PF01740
(STAS)
4 LEU A 459
LYS A 456
MET A 462
ARG A 463
None
1.42A 2gj5A-5da0A:
undetectable
2gj5A-5da0A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2g BETA-LACTAMASE

(Burkholderia
cenocepacia)
PF00144
(Beta-lactamase)
4 ASP A  71
LEU A  68
MET A 169
ARG A 172
SCN  A 402 ( 3.7A)
None
None
SCN  A 402 ( 4.7A)
1.25A 2gj5A-5e2gA:
undetectable
2gj5A-5e2gA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ftf TPR DOMAIN PROTEIN

(Bacteroides sp.
3_1_23)
PF05970
(PIF1)
4 ASP A 315
LEU A 299
MET A 284
ARG A 282
None
1.36A 2gj5A-5ftfA:
undetectable
2gj5A-5ftfA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h11 UNCHARACTERIZED
PROTEIN


(Danio rerio)
PF07393
(Sec10)
4 ASP A 537
LEU A 540
MET A 543
ARG A 609
None
1.28A 2gj5A-5h11A:
undetectable
2gj5A-5h11A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2a KLLA0C04147P

(Kluyveromyces
lactis)
PF00023
(Ank)
4 ASP A 254
LEU A 257
LYS A 258
ARG A 209
None
1.09A 2gj5A-5h2aA:
undetectable
2gj5A-5h2aA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5in8 ARISTOLOCHENE
SYNTHASE


(Aspergillus
terreus)
no annotation 4 ASP A 214
LEU A 257
LYS A 254
MET A 260
None
1.46A 2gj5A-5in8A:
undetectable
2gj5A-5in8A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbo BETA-GLUCOSIDASE

(Trichoderma
harzianum)
PF00232
(Glyco_hydro_1)
4 ASP A 110
LEU A 113
LYS A 114
ARG A 163
None
1.23A 2gj5A-5jboA:
undetectable
2gj5A-5jboA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jw9 AF4/FMR2 FAMILY
MEMBER 4
RNA POLYMERASE II
ELONGATION FACTOR
ELL2


(Homo sapiens)
PF05110
(AF-4)
PF07303
(Occludin_ELL)
4 ASP A  17
LEU A  20
LYS A  21
ARG B 576
None
1.26A 2gj5A-5jw9A:
undetectable
2gj5A-5jw9A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l5n PLEXIN-A4

(Mus musculus)
PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG)
4 ASP A  76
LEU A  77
LYS A  78
ARG A 503
ASP  A  76 ( 0.5A)
LEU  A  77 ( 0.5A)
LYS  A  78 ( 0.0A)
ARG  A 503 ( 0.6A)
1.33A 2gj5A-5l5nA:
undetectable
2gj5A-5l5nA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ls6 HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2,HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2,HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2
POLYCOMB PROTEIN
SUZ12


(Homo sapiens)
PF00856
(SET)
PF09733
(VEFS-Box)
PF11616
(EZH2_WD-Binding)
4 ASP C 629
LEU C 668
MET C 663
ARG A 287
None
1.34A 2gj5A-5ls6C:
undetectable
2gj5A-5ls6C:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t7k AOAA13

(Aspergillus
oryzae)
PF03067
(LPMO_10)
4 ASP A  38
LEU A  37
MET A  94
ARG A 157
None
1.23A 2gj5A-5t7kA:
undetectable
2gj5A-5t7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t8v PUTATIVE
UNCHARACTERIZED
PROTEIN


(Chaetomium
thermophilum)
PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C)
4 ASP A 872
LEU A 873
MET A 887
ARG A 883
None
0.97A 2gj5A-5t8vA:
undetectable
2gj5A-5t8vA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1s SEPARIN

(Saccharomyces
cerevisiae)
PF03568
(Peptidase_C50)
4 ASP A 571
LEU A 572
MET A 561
ARG A 560
None
1.33A 2gj5A-5u1sA:
undetectable
2gj5A-5u1sA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uen ADENOSINE RECEPTOR
A1,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A1


(Escherichia
coli;
Homo sapiens)
PF00001
(7tm_1)
PF07361
(Cytochrom_B562)
4 ASP A1073
LEU A1076
LYS A1077
ARG A1034
None
1.46A 2gj5A-5uenA:
undetectable
2gj5A-5uenA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ung CHIMERA PROTEIN OF
TYPE-2 ANGIOTENSIN
II RECEPTOR AND
SOLUBLE CYTOCHROME
B562


(Escherichia
coli;
Homo sapiens)
PF00001
(7tm_1)
PF07361
(Cytochrom_B562)
4 ASP B1073
LEU B1076
LYS B1077
ARG B1034
None
1.14A 2gj5A-5ungB:
undetectable
2gj5A-5ungB:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ver KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 3


(Mus musculus)
no annotation 4 ASP A 441
LEU A 440
MET A 354
ARG A 353
None
1.41A 2gj5A-5verA:
undetectable
2gj5A-5verA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xao UNCHARACTERIZED
PROTEIN


(Parastagonospora
nodorum)
PF01266
(DAO)
4 ASP A 130
LEU A 133
LYS A 134
ARG A 141
None
1.30A 2gj5A-5xaoA:
undetectable
2gj5A-5xaoA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yim SDEA

(Legionella
pneumophila)
no annotation 4 ASP A 356
LEU A 359
LYS A 360
ARG A 355
None
1.36A 2gj5A-5yimA:
undetectable
2gj5A-5yimA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq6 SIDE

(Legionella
pneumophila)
no annotation 4 ASP A 352
LEU A 355
LYS A 356
ARG A 351
None
1.26A 2gj5A-5zq6A:
undetectable
2gj5A-5zq6A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6caj TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT BETA


(Homo sapiens)
no annotation 4 ASP C 348
LEU C  86
LYS C  87
ARG C  62
None
1.20A 2gj5A-6cajC:
undetectable
2gj5A-6cajC:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccb GLYCOPROTEIN 120

(Human
immunodeficiency
virus 1)
no annotation 4 ASP C 113
LEU C 116
LYS C 117
MET C 434
None
1.42A 2gj5A-6ccbC:
undetectable
2gj5A-6ccbC:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cer PYRUVATE
DEHYDROGENASE E1
COMPONENT SUBUNIT
ALPHA, SOMATIC FORM,
MITOCHONDRIAL


(Homo sapiens)
no annotation 4 ASP A 229
LEU A 290
MET A 289
ARG A 294
None
1.31A 2gj5A-6cerA:
undetectable
2gj5A-6cerA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC1


(Saccharomyces
cerevisiae)
no annotation 4 ASP A 304
LEU A 303
LYS A 300
MET A 312
None
1.38A 2gj5A-6f42A:
undetectable
2gj5A-6f42A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fth EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1


(Bifidobacterium
longum)
no annotation 4 ASP A 341
LEU A 344
LYS A 345
MET A 103
None
1.30A 2gj5A-6fthA:
undetectable
2gj5A-6fthA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g0c UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA


(Legionella
pneumophila)
no annotation 4 ASP A 356
LEU A 359
LYS A 360
ARG A 355
None
1.32A 2gj5A-6g0cA:
undetectable
2gj5A-6g0cA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
4, MITOCHONDRIAL


(Mus musculus)
no annotation 4 ASP Q  77
LEU Q  79
MET Q  82
ARG Q  33
None
1.32A 2gj5A-6g2jQ:
undetectable
2gj5A-6g2jQ:
21.99