SIMILAR PATTERNS OF AMINO ACIDS FOR 2FT9_A_CHDA131_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)


(Escherichia
coli)
PF01053
(Cys_Met_Meta_PP)
5 LEU A 275
LEU A 280
ILE A 262
THR A 364
LEU A 359
None
1.19A 2ft9A-1cs1A:
undetectable
2ft9A-1cs1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)


(Escherichia
coli)
PF01053
(Cys_Met_Meta_PP)
5 LEU A 275
LEU A 280
THR A 364
ASN A 258
LEU A 359
None
1.34A 2ft9A-1cs1A:
undetectable
2ft9A-1cs1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebv PROSTAGLANDIN H2
SYNTHASE


(Ovis aries)
PF00008
(EGF)
PF03098
(An_peroxidase)
5 TYR A 466
LEU A 460
LEU A 458
PRO A 125
LEU A 507
None
1.35A 2ft9A-1ebvA:
0.0
2ft9A-1ebvA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA


(Desulfovibrio
gigas)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
5 TYR A 139
LEU A 143
LEU A 148
PRO A 519
LEU A 612
None
None
None
2MD  A1001 ( 4.9A)
None
1.22A 2ft9A-1h0hA:
0.0
2ft9A-1h0hA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ji6 PESTICIDIAL CRYSTAL
PROTEIN CRY3BB


(Bacillus
thuringiensis)
PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
5 LEU A 280
LEU A 283
ILE A  99
THR A  98
LEU A 275
None
1.15A 2ft9A-1ji6A:
undetectable
2ft9A-1ji6A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1la2 MYO-INOSITOL-1-PHOSP
HATE SYNTHASE


(Saccharomyces
cerevisiae)
PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5)
5 LEU A 510
LEU A 514
GLN A 111
MET A 136
LEU A 481
None
1.04A 2ft9A-1la2A:
0.0
2ft9A-1la2A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1la2 MYO-INOSITOL-1-PHOSP
HATE SYNTHASE


(Saccharomyces
cerevisiae)
PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5)
5 LEU A 510
PRO A 444
GLN A 111
MET A 136
LEU A 481
None
1.10A 2ft9A-1la2A:
0.0
2ft9A-1la2A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m54 CYSTATHIONINE
BETA-SYNTHASE


(Homo sapiens)
PF00291
(PALP)
5 LEU A  81
ILE A 122
THR A 150
ASN A 149
LEU A 136
None
None
None
PLP  A1110 (-3.6A)
None
1.32A 2ft9A-1m54A:
0.0
2ft9A-1m54A:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1p6p FATTY ACID-BINDING
PROTEIN, LIVER


(Rhinella
arenarum)
PF14651
(Lipocalin_7)
5 LEU A  23
THR A  53
PRO A  54
GLN A  56
LEU A 118
None
1.12A 2ft9A-1p6pA:
20.6
2ft9A-1p6pA:
73.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1p6p FATTY ACID-BINDING
PROTEIN, LIVER


(Rhinella
arenarum)
PF14651
(Lipocalin_7)
7 TYR A  14
LEU A  18
LEU A  23
THR A  53
PRO A  54
GLN A  56
ARG A 120
None
0.79A 2ft9A-1p6pA:
20.6
2ft9A-1p6pA:
73.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5h DUTP PYROPHOSPHATASE

(Homo sapiens)
PF00692
(dUTPase)
5 LEU A   3
LEU A  51
ILE A  47
THR A  45
ASN A  85
None
1.15A 2ft9A-1q5hA:
undetectable
2ft9A-1q5hA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qib 72 KDA TYPE IV
COLLAGENASE


(Homo sapiens)
PF00413
(Peptidase_M10)
5 LEU A 209
THR A 128
PRO A 129
ASN A  95
LEU A 218
None
1.33A 2ft9A-1qibA:
undetectable
2ft9A-1qibA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qv9 F420-DEPENDENT
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE


(Methanopyrus
kandleri)
PF01993
(MTD)
5 LEU A 148
LEU A 144
PRO A  75
ASN A  74
LEU A  23
None
1.34A 2ft9A-1qv9A:
undetectable
2ft9A-1qv9A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tff UBIQUITIN
THIOLESTERASE
PROTEIN OTUB2


(Homo sapiens)
PF10275
(Peptidase_C65)
5 LEU A  61
LEU A  64
THR A  81
PRO A  82
LEU A  56
None
0.97A 2ft9A-1tffA:
undetectable
2ft9A-1tffA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u9c APC35852

(Geobacillus
stearothermophilus)
PF01965
(DJ-1_PfpI)
5 LEU A 132
LEU A 112
ILE A 198
THR A 209
LEU A 170
None
1.34A 2ft9A-1u9cA:
undetectable
2ft9A-1u9cA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wue MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN


(Enterococcus
faecalis)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 LEU A1076
LEU A1077
ILE A1068
MET A1367
LEU A1111
None
1.20A 2ft9A-1wueA:
undetectable
2ft9A-1wueA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xxi DNA POLYMERASE III
SUBUNIT GAMMA


(Escherichia
coli)
PF12169
(DNA_pol3_gamma3)
PF13177
(DNA_pol3_delta2)
5 LEU B 286
LEU B 289
ILE B 334
MET B 256
LEU B 281
None
1.13A 2ft9A-1xxiB:
undetectable
2ft9A-1xxiB:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zkl HIGH-AFFINITY
CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 7A


(Homo sapiens)
PF00233
(PDEase_I)
5 LEU A 298
ILE A 201
THR A 251
MET A 310
LEU A 183
None
1.21A 2ft9A-1zklA:
undetectable
2ft9A-1zklA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgk GLUTAMATE
DECARBOXYLASE BETA


(Escherichia
coli)
PF00282
(Pyridoxal_deC)
5 LEU A 227
ILE A 203
PRO A 155
ASN A 201
MET A 194
None
1.32A 2ft9A-2dgkA:
undetectable
2ft9A-2dgkA:
14.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ftb FATTY ACID-BINDING
PROTEIN 2, LIVER


(Ambystoma
mexicanum)
PF14651
(Lipocalin_7)
6 ILE A  34
THR A  53
PRO A  54
ASN A  55
GLN A  56
MET A  73
None
OLA  A 130 ( 4.7A)
None
None
OLA  A 130 ( 4.4A)
OLA  A 130 (-4.6A)
1.26A 2ft9A-2ftbA:
23.0
2ft9A-2ftbA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ftb FATTY ACID-BINDING
PROTEIN 2, LIVER


(Ambystoma
mexicanum)
PF14651
(Lipocalin_7)
5 ILE A  34
THR A  53
PRO A  54
ASN A  55
LEU A 111
None
OLA  A 130 ( 4.7A)
None
None
None
1.11A 2ft9A-2ftbA:
23.0
2ft9A-2ftbA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ftb FATTY ACID-BINDING
PROTEIN 2, LIVER


(Ambystoma
mexicanum)
PF14651
(Lipocalin_7)
7 TYR A  14
LEU A  18
LEU A  23
ILE A  34
THR A  53
PRO A  54
GLN A  56
None
None
None
None
OLA  A 130 ( 4.7A)
None
OLA  A 130 ( 4.4A)
1.06A 2ft9A-2ftbA:
23.0
2ft9A-2ftbA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ftb FATTY ACID-BINDING
PROTEIN 2, LIVER


(Ambystoma
mexicanum)
PF14651
(Lipocalin_7)
8 TYR A  14
LEU A  18
LEU A  23
ILE A  34
THR A  53
PRO A  54
LEU A 111
ARG A 120
None
None
None
None
OLA  A 130 ( 4.7A)
None
None
None
0.70A 2ft9A-2ftbA:
23.0
2ft9A-2ftbA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hro PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE


(Staphylococcus
carnosus)
PF00391
(PEP-utilizers)
PF02896
(PEP-utilizers_C)
PF05524
(PEP-utilisers_N)
5 LEU A  78
LEU A  81
ILE A  58
PRO A 150
ASN A 149
None
1.10A 2ft9A-2hroA:
undetectable
2ft9A-2hroA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lkm PHD FINGER PROTEIN
12
MORTALITY FACTOR
4-LIKE PROTEIN 1


(Homo sapiens;
Homo sapiens)
PF16737
(PHF12_MRG_bd)
PF05712
(MRG)
5 LEU A 213
THR B 231
PRO A 222
ASN A 221
LEU B 263
None
1.36A 2ft9A-2lkmA:
undetectable
2ft9A-2lkmA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2osa N-CHIMAERIN

(Homo sapiens)
PF00620
(RhoGAP)
5 LEU A 379
LEU A 450
ILE A 364
ASN A 439
LEU A 394
None
1.36A 2ft9A-2osaA:
undetectable
2ft9A-2osaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qb6 EXOPOLYPHOSPHATASE

(Saccharomyces
cerevisiae)
PF01368
(DHH)
PF02833
(DHHA2)
5 LEU A 320
LEU A 339
ILE A 287
THR A 324
LEU A 388
None
1.25A 2ft9A-2qb6A:
undetectable
2ft9A-2qb6A:
16.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qo4 LIVER-BASIC FATTY
ACID BINDING PROTEIN


(Danio rerio)
PF14651
(Lipocalin_7)
5 TYR A  14
LEU A  18
THR A  53
PRO A  54
LEU A 111
None
CHD  A 130 ( 4.7A)
CHD  A 130 ( 4.1A)
None
CHD  A 130 ( 4.9A)
0.95A 2ft9A-2qo4A:
20.7
2ft9A-2qo4A:
69.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qtz METHIONINE SYNTHASE
REDUCTASE


(Homo sapiens)
PF00175
(NAD_binding_1)
PF00667
(FAD_binding_1)
5 LEU A 328
LEU A 333
ILE A 369
PRO A 361
LEU A 424
None
1.19A 2ft9A-2qtzA:
undetectable
2ft9A-2qtzA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3b YJEF-RELATED PROTEIN

(Enterococcus
faecalis)
PF01256
(Carb_kinase)
5 LEU A 112
LEU A 116
ILE A 132
THR A 151
PRO A 152
None
1.36A 2ft9A-2r3bA:
undetectable
2ft9A-2r3bA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw THIOSULFATE
REDUCTASE


(Thermus
thermophilus)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
5 LEU A 548
LEU A 553
THR A 506
PRO A 507
MET A 561
None
1.28A 2ft9A-2vpwA:
undetectable
2ft9A-2vpwA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3z PUTATIVE DEACETYLASE

(Streptococcus
mutans)
PF01522
(Polysacc_deac_1)
5 LEU A 201
LEU A 197
ILE A 152
THR A 122
PRO A 123
None
1.17A 2ft9A-2w3zA:
undetectable
2ft9A-2w3zA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x47 MACRO
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF01661
(Macro)
5 LEU A 287
LEU A 301
ILE A 267
THR A 226
ASN A 171
None
1.07A 2ft9A-2x47A:
undetectable
2ft9A-2x47A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfv REGULATORY PROTEIN
SWI6


(Saccharomyces
cerevisiae)
no annotation 5 LEU A  96
ILE A  16
PRO A  52
ASN A  51
LEU A  20
None
1.20A 2ft9A-2xfvA:
undetectable
2ft9A-2xfvA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfv REGULATORY PROTEIN
SWI6


(Saccharomyces
cerevisiae)
no annotation 5 LEU A  96
LEU A  94
ILE A  16
PRO A  52
ASN A  51
None
1.03A 2ft9A-2xfvA:
undetectable
2ft9A-2xfvA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvn ASPERGILLUS
FUMIGATUS CHITINASE
A1


(Aspergillus
fumigatus)
PF00704
(Glyco_hydro_18)
5 LEU A 294
LEU A 286
ILE A 229
PRO A 206
LEU A 335
None
1.27A 2ft9A-2xvnA:
undetectable
2ft9A-2xvnA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yvt HYPOTHETICAL PROTEIN
AQ_1956


(Aquifex
aeolicus)
PF14582
(Metallophos_3)
5 LEU A 165
ILE A 208
THR A 231
ASN A 230
LEU A 123
None
1.23A 2ft9A-2yvtA:
undetectable
2ft9A-2yvtA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5i FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA


(Salmonella
enterica)
PF00771
(FHIPEP)
5 LEU A 610
LEU A 654
ILE A 689
THR A 632
LEU A 620
None
1.36A 2ft9A-3a5iA:
undetectable
2ft9A-3a5iA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ay3 NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E


(Chromohalobacter
salexigens)
PF01370
(Epimerase)
5 LEU A   5
LEU A  25
ILE A 105
ASN A 159
LEU A  31
None
1.36A 2ft9A-3ay3A:
undetectable
2ft9A-3ay3A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE


(Shewanella
denitrificans)
PF04952
(AstE_AspA)
5 LEU A  69
ILE A  53
PRO A 110
ASN A 109
LEU A  40
None
0.99A 2ft9A-3b2yA:
undetectable
2ft9A-3b2yA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bcq ALPHA-CHAIN
HEMOGLOBIN


(Brycon cephalus)
PF00042
(Globin)
5 LEU A 130
LEU A 106
ILE A  10
MET A  64
LEU A 137
None
1.23A 2ft9A-3bcqA:
undetectable
2ft9A-3bcqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cob KINESIN HEAVY
CHAIN-LIKE PROTEIN


(Solanum
tuberosum)
PF00225
(Kinesin)
5 LEU A1028
LEU A1027
ILE A1068
THR A 990
PRO A 991
None
1.29A 2ft9A-3cobA:
undetectable
2ft9A-3cobA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg4 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN


(Plexaura
homomalla)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
5 LEU A 776
LEU A 786
ILE A 899
PRO A 919
LEU A 492
None
1.36A 2ft9A-3fg4A:
0.1
2ft9A-3fg4A:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h09 IMMUNOGLOBULIN A1
PROTEASE


(Haemophilus
influenzae)
PF02395
(Peptidase_S6)
PF03212
(Pertactin)
5 LEU A 410
LEU A 391
ILE A 403
PRO A 353
ASN A 352
None
None
None
MLA  A2100 (-3.9A)
None
1.18A 2ft9A-3h09A:
undetectable
2ft9A-3h09A:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1z HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN 3


(Homo sapiens)
PF13419
(HAD_2)
5 LEU A  45
LEU A  25
ILE A  97
PRO A  96
LEU A  85
None
1.16A 2ft9A-3k1zA:
undetectable
2ft9A-3k1zA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kn1 GOLGI PHOSPHOPROTEIN
3


(Homo sapiens)
PF05719
(GPP34)
5 LEU A 170
LEU A 156
THR A 128
PRO A 127
LEU A 177
None
1.11A 2ft9A-3kn1A:
undetectable
2ft9A-3kn1A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8q CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B


(Acetivibrio
cellulolyticus)
PF00963
(Cohesin)
5 TYR A  95
LEU A  76
ILE A  69
ASN A  27
LEU A  98
None
1.34A 2ft9A-3l8qA:
undetectable
2ft9A-3l8qA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3la6 TYROSINE-PROTEIN
KINASE WZC


(Escherichia
coli)
PF13614
(AAA_31)
5 LEU A 574
LEU A 573
PRO A 502
ASN A 501
LEU A 640
None
1.32A 2ft9A-3la6A:
undetectable
2ft9A-3la6A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lx2 DNA POLYMERASE
SLIDING CLAMP 2


(Thermococcus
kodakarensis)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
5 LEU A  73
LEU A  20
THR A 120
PRO A 121
LEU A  99
None
1.12A 2ft9A-3lx2A:
2.0
2ft9A-3lx2A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjp COVR

(Streptococcus
pyogenes)
PF00486
(Trans_reg_C)
5 LEU A 162
LEU A 179
ILE A 225
ASN A 171
ARG A 203
None
1.37A 2ft9A-3rjpA:
undetectable
2ft9A-3rjpA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rkx BIOTIN-[ACETYL-COA-C
ARBOXYLASE] LIGASE


(Staphylococcus
aureus)
PF03099
(BPL_LplA_LipB)
PF08279
(HTH_11)
5 LEU A 249
ILE A  71
GLN A  69
LEU A 213
ARG A 241
None
1.13A 2ft9A-3rkxA:
undetectable
2ft9A-3rkxA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tht ALKYLATED DNA REPAIR
PROTEIN ALKB HOMOLOG
8


(Homo sapiens)
PF00076
(RRM_1)
PF13532
(2OG-FeII_Oxy_2)
5 LEU A  30
LEU A  29
PRO A  78
ASN A  79
LEU A 117
None
1.18A 2ft9A-3thtA:
undetectable
2ft9A-3thtA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ved DYPB

(Rhodococcus
jostii)
PF04261
(Dyp_perox)
5 LEU A  49
LEU A 119
THR A  15
PRO A  16
LEU A 310
None
1.17A 2ft9A-3vedA:
undetectable
2ft9A-3vedA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vn3 ANTIFREEZE PROTEIN

(Typhula
ishikariensis)
PF11999
(DUF3494)
5 TYR A  14
LEU A  17
ILE A  79
THR A  76
PRO A  75
EDO  A 303 (-4.2A)
None
None
None
None
1.34A 2ft9A-3vn3A:
undetectable
2ft9A-3vn3A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vnp HYPOTHETICAL
CONSERVED PROTEIN


(Geobacillus
kaustophilus)
PF00132
(Hexapep)
5 LEU A  63
LEU A  85
ILE A  30
THR A  34
ASN A  53
None
1.16A 2ft9A-3vnpA:
undetectable
2ft9A-3vnpA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr5 V-TYPE SODIUM ATPASE
CATALYTIC SUBUNIT A


(Enterococcus
hirae)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn)
5 TYR A 366
LEU A 362
LEU A 358
ILE A 307
LEU A 406
None
1.32A 2ft9A-3vr5A:
undetectable
2ft9A-3vr5A:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vvd AMINO ACID ABC
TRANSPORTER, BINDING
PROTEIN


(Thermus
thermophilus)
PF00497
(SBP_bac_3)
5 LEU A  64
LEU A  67
ILE A  81
PRO A  94
ASN A  93
None
1.31A 2ft9A-3vvdA:
undetectable
2ft9A-3vvdA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vyl L-RIBULOSE
3-EPIMERASE


(Mesorhizobium
loti)
PF01261
(AP_endonuc_2)
5 LEU A  59
LEU A  57
ILE A   6
ASN A 266
LEU A  98
None
1.37A 2ft9A-3vylA:
undetectable
2ft9A-3vylA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wp9 ICE-BINDING PROTEIN

(Colwellia sp.
SLW05)
PF11999
(DUF3494)
5 LEU A  45
ILE A  39
PRO A  38
MET A  55
LEU A 209
None
1.09A 2ft9A-3wp9A:
undetectable
2ft9A-3wp9A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfr PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC S
SUBUNIT BETA ISOFORM


(Mus musculus)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
5 LEU A 936
LEU A 909
PRO A 540
ASN A 992
LEU A1006
None
1.23A 2ft9A-4bfrA:
undetectable
2ft9A-4bfrA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxw FACTOR XA

(Pseudonaja
textilis)
PF00089
(Trypsin)
PF14670
(FXa_inhibition)
5 LEU A 201
LEU A 286
ILE A 266
THR A 396
ASN A 344
None
1.25A 2ft9A-4bxwA:
undetectable
2ft9A-4bxwA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1


(Saccharomyces
cerevisiae)
PF04054
(Not1)
5 LEU A1972
LEU A1969
ILE A1908
PRO A1892
ASN A1895
None
1.34A 2ft9A-4by6A:
undetectable
2ft9A-4by6A:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d72 GLYCOSIDE HYDROLASE

(Streptococcus
pneumoniae)
PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C)
5 LEU A1001
LEU A 895
ILE A 991
THR A 950
ASN A 901
None
1.18A 2ft9A-4d72A:
3.2
2ft9A-4d72A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d72 GLYCOSIDE HYDROLASE

(Streptococcus
pneumoniae)
PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C)
5 LEU A1001
LEU A 895
ILE A 991
THR A 950
MET A 876
None
1.26A 2ft9A-4d72A:
3.2
2ft9A-4d72A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4db3 N-ACETYL-D-GLUCOSAMI
NE KINASE


(Vibrio
vulnificus)
PF00480
(ROK)
5 LEU A 130
LEU A 255
ILE A 282
PRO A 266
LEU A 185
None
1.30A 2ft9A-4db3A:
undetectable
2ft9A-4db3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emk U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM5
U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM7


(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe)
PF01423
(LSM)
PF01423
(LSM)
5 LEU A  44
LEU A  65
ILE A  11
ASN C  58
MET A  23
None
1.01A 2ft9A-4emkA:
undetectable
2ft9A-4emkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN


(Burkholderia
pseudomallei)
PF00497
(SBP_bac_3)
5 LEU A 169
ILE A 135
PRO A 153
ASN A 131
ARG A 157
None
1.05A 2ft9A-4f3pA:
undetectable
2ft9A-4f3pA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f52 CULLIN-1

(Homo sapiens)
PF00888
(Cullin)
5 LEU A 643
LEU A 649
ILE A 631
THR A 629
LEU A 590
None
1.31A 2ft9A-4f52A:
undetectable
2ft9A-4f52A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ffk SUPEROXIDE DISMUTASE

(Acidilobus
saccharovorans)
PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C)
5 LEU A  94
LEU A  91
ILE A 172
PRO A 150
ASN A 170
None
0.91A 2ft9A-4ffkA:
undetectable
2ft9A-4ffkA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h62 MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 17


(Saccharomyces
cerevisiae)
PF10156
(Med17)
5 LEU Q 478
LEU Q 479
ILE Q 435
MET Q 411
LEU Q 508
None
1.10A 2ft9A-4h62Q:
3.7
2ft9A-4h62Q:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i93 PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE
AT5G41260


(Arabidopsis
thaliana)
PF07714
(Pkinase_Tyr)
5 LEU A 293
ILE A 235
PRO A 303
ASN A 302
LEU A 246
None
1.33A 2ft9A-4i93A:
undetectable
2ft9A-4i93A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7q PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
PDR16


(Saccharomyces
cerevisiae)
PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N)
5 LEU A 237
LEU A 195
ILE A 199
PRO A 162
GLN A 145
B7N  A 401 (-3.9A)
B7N  A 401 ( 4.9A)
None
None
None
1.27A 2ft9A-4j7qA:
undetectable
2ft9A-4j7qA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lk3 UDP-GLUCURONIC ACID
DECARBOXYLASE 1


(Homo sapiens)
PF16363
(GDP_Man_Dehyd)
5 LEU A 312
ILE A 365
PRO A 326
ASN A 325
GLN A 300
None
1.19A 2ft9A-4lk3A:
undetectable
2ft9A-4lk3A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqh GLUTATHIONE
TRANSFERASE LAMBDA1


(Populus
trichocarpa)
PF13410
(GST_C_2)
PF13417
(GST_N_3)
5 ILE A  44
THR A 217
ASN A 215
GLN A 216
LEU A  82
None
1.31A 2ft9A-4pqhA:
undetectable
2ft9A-4pqhA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pw8 TRYPTOPHAN
2,3-DIOXYGENASE


(Homo sapiens)
PF03301
(Trp_dioxygenase)
5 LEU A 365
LEU A 368
THR A 212
PRO A 213
LEU A 202
None
1.31A 2ft9A-4pw8A:
undetectable
2ft9A-4pw8A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgj CALCIUM-DEPENDENT
PROTEIN KINASE 4


(Plasmodium
falciparum)
PF00069
(Pkinase)
PF13499
(EF-hand_7)
5 LEU A 260
LEU A 264
ILE A 328
THR A 332
LEU A 155
None
1.37A 2ft9A-4rgjA:
undetectable
2ft9A-4rgjA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s2t PROTEIN APP-1

(Caenorhabditis
elegans)
PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2)
5 LEU P 573
LEU P 574
ILE P 439
PRO P 434
LEU P 474
None
1.29A 2ft9A-4s2tP:
undetectable
2ft9A-4s2tP:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u06 LIC10831

(Leptospira
interrogans)
PF12799
(LRR_4)
PF13855
(LRR_8)
5 LEU A 209
LEU A 229
ILE A 180
PRO A 177
ASN A 178
None
None
None
None
ZN  A 403 (-2.6A)
1.24A 2ft9A-4u06A:
undetectable
2ft9A-4u06A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufs LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5


(Homo sapiens)
PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8)
5 LEU A  97
LEU A  95
PRO A  83
ASN A  84
LEU A 126
None
1.15A 2ft9A-4ufsA:
undetectable
2ft9A-4ufsA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wpm MRNA EXPORT PROTEIN

(Chaetomium
thermophilum)
no annotation 5 LEU A 123
LEU A 136
ILE A 140
PRO A 181
LEU A 171
None
1.35A 2ft9A-4wpmA:
undetectable
2ft9A-4wpmA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xrt STFQ
AROMATASE/CYCLASE


(Streptomyces
steffisburgensis)
PF03364
(Polyketide_cyc)
5 TYR A 283
LEU A 271
THR A 206
PRO A 207
LEU A 237
None
1.22A 2ft9A-4xrtA:
2.7
2ft9A-4xrtA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yir UV EXCISION REPAIR
PROTEIN RAD23


(Saccharomyces
cerevisiae)
PF09280
(XPC-binding)
5 LEU X 265
LEU X 262
ILE X 294
PRO X 298
ASN X 297
None
1.36A 2ft9A-4yirX:
undetectable
2ft9A-4yirX:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmi TELOMERE LENGTH
REGULATOR TAZ1


(Schizosaccharomyces
pombe)
PF08558
(TRF)
5 LEU A 251
LEU A 254
ILE A 326
ASN A 328
LEU A 246
None
1.13A 2ft9A-4zmiA:
undetectable
2ft9A-4zmiA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6f GATING RING OF
POTASSIUM CHANNEL
SUBFAMILY T MEMBER 1


(Gallus gallus)
PF03493
(BK_channel_a)
5 LEU C 512
LEU C 508
ILE C 575
ASN C 588
LEU C 951
None
1.15A 2ft9A-5a6fC:
undetectable
2ft9A-5a6fC:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b5h ANTIFREEZE PROTEIN

(Typhula
ishikariensis)
PF11999
(DUF3494)
5 TYR A  14
LEU A  17
ILE A  79
THR A  76
PRO A  75
None
1.33A 2ft9A-5b5hA:
undetectable
2ft9A-5b5hA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN


(Staphylococcus
epidermidis)
no annotation 5 LEU A 458
LEU A 420
ILE A 448
PRO A 464
LEU A 357
None
1.32A 2ft9A-5bndA:
undetectable
2ft9A-5bndA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnd ABC TRANSPORTER,
ATP-BINDING PROTEIN


(Staphylococcus
epidermidis)
no annotation 5 LEU A 458
LEU A 420
PRO A 447
ASN A 408
LEU A 357
None
1.35A 2ft9A-5bndA:
undetectable
2ft9A-5bndA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c78 ATP-DRIVEN FLIPPASE
PGLK


(Campylobacter
jejuni)
PF00005
(ABC_tran)
PF00664
(ABC_membrane)
5 TYR A  93
LEU A  97
PRO A 305
ASN A 308
LEU A  21
None
1.35A 2ft9A-5c78A:
undetectable
2ft9A-5c78A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c8w CGMP-DEPENDENT
PROTEIN KINASE 2


(Homo sapiens)
PF00027
(cNMP_binding)
5 LEU A 169
LEU A 163
ILE A 236
ASN A 203
MET A 184
None
None
None
MLA  A 301 (-4.9A)
None
1.36A 2ft9A-5c8wA:
undetectable
2ft9A-5c8wA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5goo ALKALINE INVERTASE

(Nostoc sp. PCC
7120)
PF12899
(Glyco_hydro_100)
5 LEU A 136
ILE A 200
PRO A 197
MET A 311
LEU A 232
None
1.28A 2ft9A-5gooA:
undetectable
2ft9A-5gooA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hiw CYTOCHROME P450
CYP260B1


(Sorangium
cellulosum)
PF00067
(p450)
5 LEU A 362
LEU A 356
ILE A 387
PRO A 384
ASN A 239
None
1.13A 2ft9A-5hiwA:
undetectable
2ft9A-5hiwA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m85 SENSORY TRANSDUCTION
HISTIDINE KINASE


(Synechocystis
sp. PCC 6803)
no annotation 5 LEU A 441
PRO A 468
ASN A 467
LEU A 591
ARG A 594
None
1.37A 2ft9A-5m85A:
undetectable
2ft9A-5m85A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mea CELL DIVISION CYCLE
PROTEIN CDT1


(Saccharomyces
cerevisiae)
no annotation 5 TYR A 371
LEU A 363
THR A 323
MET A 351
LEU A 340
None
1.37A 2ft9A-5meaA:
1.5
2ft9A-5meaA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6t PLEXIN-D1

(Mus musculus)
PF08337
(Plexin_cytopl)
5 LEU A1795
LEU A1776
ILE A1785
PRO A1347
LEU A1714
None
1.32A 2ft9A-5v6tA:
undetectable
2ft9A-5v6tA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v72 NADPH-DEPENDENT
GLYOXYLATE/HYDROXYPY
RUVATE REDUCTASE


(Sinorhizobium
meliloti)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
5 LEU A 219
LEU A 216
ILE A 226
THR A 111
ARG A 143
None
1.32A 2ft9A-5v72A:
undetectable
2ft9A-5v72A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z95 -

(-)
no annotation 5 LEU A 202
LEU A 232
PRO A 221
GLN A 213
MET A 117
None
None
GOL  A 304 ( 4.9A)
None
None
1.13A 2ft9A-5z95A:
undetectable
2ft9A-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zya SPLICING FACTOR 3B
SUBUNIT 1


(Homo sapiens)
no annotation 5 LEU C 560
LEU C 600
PRO C 530
ASN C 533
ARG C 524
None
1.26A 2ft9A-5zyaC:
undetectable
2ft9A-5zyaC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6an0 HISTIDINOL
DEHYDROGENASE


(Elizabethkingia
anophelis)
PF00815
(Histidinol_dh)
5 LEU A 278
ILE A 304
PRO A   7
ASN A   6
LEU A 299
None
None
None
IOD  A 509 (-4.1A)
None
1.29A 2ft9A-6an0A:
undetectable
2ft9A-6an0A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae)
no annotation 5 LEU A  78
LEU A  76
THR A 826
ASN A 824
LEU A 102
None
1.34A 2ft9A-6eojA:
undetectable
2ft9A-6eojA:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2


(Mus musculus)
no annotation 5 LEU N  99
LEU N 102
THR N 201
ASN N 204
LEU N 148
None
1.28A 2ft9A-6g72N:
undetectable
2ft9A-6g72N:
undetectable