SIMILAR PATTERNS OF AMINO ACIDS FOR 2FT9_A_CHDA131
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU A 275LEU A 280ILE A 262THR A 364LEU A 359 | None | 1.19A | 2ft9A-1cs1A:undetectable | 2ft9A-1cs1A:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU A 275LEU A 280THR A 364ASN A 258LEU A 359 | None | 1.34A | 2ft9A-1cs1A:undetectable | 2ft9A-1cs1A:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebv | PROSTAGLANDIN H2SYNTHASE (Ovis aries) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | TYR A 466LEU A 460LEU A 458PRO A 125LEU A 507 | None | 1.35A | 2ft9A-1ebvA:0.0 | 2ft9A-1ebvA:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0h | FORMATEDEHYDROGENASESUBUNIT ALPHA (Desulfovibriogigas) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 5 | TYR A 139LEU A 143LEU A 148PRO A 519LEU A 612 | NoneNoneNone2MD A1001 ( 4.9A)None | 1.22A | 2ft9A-1h0hA:0.0 | 2ft9A-1h0hA:9.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ji6 | PESTICIDIAL CRYSTALPROTEIN CRY3BB (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | LEU A 280LEU A 283ILE A 99THR A 98LEU A 275 | None | 1.15A | 2ft9A-1ji6A:undetectable | 2ft9A-1ji6A:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1la2 | MYO-INOSITOL-1-PHOSPHATE SYNTHASE (Saccharomycescerevisiae) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 5 | LEU A 510LEU A 514GLN A 111MET A 136LEU A 481 | None | 1.04A | 2ft9A-1la2A:0.0 | 2ft9A-1la2A:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1la2 | MYO-INOSITOL-1-PHOSPHATE SYNTHASE (Saccharomycescerevisiae) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 5 | LEU A 510PRO A 444GLN A 111MET A 136LEU A 481 | None | 1.10A | 2ft9A-1la2A:0.0 | 2ft9A-1la2A:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m54 | CYSTATHIONINEBETA-SYNTHASE (Homo sapiens) |
PF00291(PALP) | 5 | LEU A 81ILE A 122THR A 150ASN A 149LEU A 136 | NoneNoneNonePLP A1110 (-3.6A)None | 1.32A | 2ft9A-1m54A:0.0 | 2ft9A-1m54A:16.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p6p | FATTY ACID-BINDINGPROTEIN, LIVER (Rhinellaarenarum) |
PF14651(Lipocalin_7) | 5 | LEU A 23THR A 53PRO A 54GLN A 56LEU A 118 | None | 1.12A | 2ft9A-1p6pA:20.6 | 2ft9A-1p6pA:73.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p6p | FATTY ACID-BINDINGPROTEIN, LIVER (Rhinellaarenarum) |
PF14651(Lipocalin_7) | 7 | TYR A 14LEU A 18LEU A 23THR A 53PRO A 54GLN A 56ARG A 120 | None | 0.79A | 2ft9A-1p6pA:20.6 | 2ft9A-1p6pA:73.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5h | DUTP PYROPHOSPHATASE (Homo sapiens) |
PF00692(dUTPase) | 5 | LEU A 3LEU A 51ILE A 47THR A 45ASN A 85 | None | 1.15A | 2ft9A-1q5hA:undetectable | 2ft9A-1q5hA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qib | 72 KDA TYPE IVCOLLAGENASE (Homo sapiens) |
PF00413(Peptidase_M10) | 5 | LEU A 209THR A 128PRO A 129ASN A 95LEU A 218 | None | 1.33A | 2ft9A-1qibA:undetectable | 2ft9A-1qibA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qv9 | F420-DEPENDENTMETHYLENETETRAHYDROMETHANOPTERINDEHYDROGENASE (Methanopyruskandleri) |
PF01993(MTD) | 5 | LEU A 148LEU A 144PRO A 75ASN A 74LEU A 23 | None | 1.34A | 2ft9A-1qv9A:undetectable | 2ft9A-1qv9A:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tff | UBIQUITINTHIOLESTERASEPROTEIN OTUB2 (Homo sapiens) |
PF10275(Peptidase_C65) | 5 | LEU A 61LEU A 64THR A 81PRO A 82LEU A 56 | None | 0.97A | 2ft9A-1tffA:undetectable | 2ft9A-1tffA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u9c | APC35852 (Geobacillusstearothermophilus) |
PF01965(DJ-1_PfpI) | 5 | LEU A 132LEU A 112ILE A 198THR A 209LEU A 170 | None | 1.34A | 2ft9A-1u9cA:undetectable | 2ft9A-1u9cA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wue | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Enterococcusfaecalis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A1076LEU A1077ILE A1068MET A1367LEU A1111 | None | 1.20A | 2ft9A-1wueA:undetectable | 2ft9A-1wueA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xxi | DNA POLYMERASE IIISUBUNIT GAMMA (Escherichiacoli) |
PF12169(DNA_pol3_gamma3)PF13177(DNA_pol3_delta2) | 5 | LEU B 286LEU B 289ILE B 334MET B 256LEU B 281 | None | 1.13A | 2ft9A-1xxiB:undetectable | 2ft9A-1xxiB:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkl | HIGH-AFFINITYCAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 7A (Homo sapiens) |
PF00233(PDEase_I) | 5 | LEU A 298ILE A 201THR A 251MET A 310LEU A 183 | None | 1.21A | 2ft9A-1zklA:undetectable | 2ft9A-1zklA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dgk | GLUTAMATEDECARBOXYLASE BETA (Escherichiacoli) |
PF00282(Pyridoxal_deC) | 5 | LEU A 227ILE A 203PRO A 155ASN A 201MET A 194 | None | 1.32A | 2ft9A-2dgkA:undetectable | 2ft9A-2dgkA:14.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 6 | ILE A 34THR A 53PRO A 54ASN A 55GLN A 56MET A 73 | NoneOLA A 130 ( 4.7A)NoneNoneOLA A 130 ( 4.4A)OLA A 130 (-4.6A) | 1.26A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 5 | ILE A 34THR A 53PRO A 54ASN A 55LEU A 111 | NoneOLA A 130 ( 4.7A)NoneNoneNone | 1.11A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 7 | TYR A 14LEU A 18LEU A 23ILE A 34THR A 53PRO A 54GLN A 56 | NoneNoneNoneNoneOLA A 130 ( 4.7A)NoneOLA A 130 ( 4.4A) | 1.06A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 8 | TYR A 14LEU A 18LEU A 23ILE A 34THR A 53PRO A 54LEU A 111ARG A 120 | NoneNoneNoneNoneOLA A 130 ( 4.7A)NoneNoneNone | 0.70A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hro | PHOSPHOENOLPYRUVATE-PROTEINPHOSPHOTRANSFERASE (Staphylococcuscarnosus) |
PF00391(PEP-utilizers)PF02896(PEP-utilizers_C)PF05524(PEP-utilisers_N) | 5 | LEU A 78LEU A 81ILE A 58PRO A 150ASN A 149 | None | 1.10A | 2ft9A-2hroA:undetectable | 2ft9A-2hroA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lkm | PHD FINGER PROTEIN12MORTALITY FACTOR4-LIKE PROTEIN 1 (Homo sapiens;Homo sapiens) |
PF16737(PHF12_MRG_bd)PF05712(MRG) | 5 | LEU A 213THR B 231PRO A 222ASN A 221LEU B 263 | None | 1.36A | 2ft9A-2lkmA:undetectable | 2ft9A-2lkmA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2osa | N-CHIMAERIN (Homo sapiens) |
PF00620(RhoGAP) | 5 | LEU A 379LEU A 450ILE A 364ASN A 439LEU A 394 | None | 1.36A | 2ft9A-2osaA:undetectable | 2ft9A-2osaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qb6 | EXOPOLYPHOSPHATASE (Saccharomycescerevisiae) |
PF01368(DHH)PF02833(DHHA2) | 5 | LEU A 320LEU A 339ILE A 287THR A 324LEU A 388 | None | 1.25A | 2ft9A-2qb6A:undetectable | 2ft9A-2qb6A:16.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qo4 | LIVER-BASIC FATTYACID BINDING PROTEIN (Danio rerio) |
PF14651(Lipocalin_7) | 5 | TYR A 14LEU A 18THR A 53PRO A 54LEU A 111 | NoneCHD A 130 ( 4.7A)CHD A 130 ( 4.1A)NoneCHD A 130 ( 4.9A) | 0.95A | 2ft9A-2qo4A:20.7 | 2ft9A-2qo4A:69.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qtz | METHIONINE SYNTHASEREDUCTASE (Homo sapiens) |
PF00175(NAD_binding_1)PF00667(FAD_binding_1) | 5 | LEU A 328LEU A 333ILE A 369PRO A 361LEU A 424 | None | 1.19A | 2ft9A-2qtzA:undetectable | 2ft9A-2qtzA:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r3b | YJEF-RELATED PROTEIN (Enterococcusfaecalis) |
PF01256(Carb_kinase) | 5 | LEU A 112LEU A 116ILE A 132THR A 151PRO A 152 | None | 1.36A | 2ft9A-2r3bA:undetectable | 2ft9A-2r3bA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpw | THIOSULFATEREDUCTASE (Thermusthermophilus) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 5 | LEU A 548LEU A 553THR A 506PRO A 507MET A 561 | None | 1.28A | 2ft9A-2vpwA:undetectable | 2ft9A-2vpwA:9.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3z | PUTATIVE DEACETYLASE (Streptococcusmutans) |
PF01522(Polysacc_deac_1) | 5 | LEU A 201LEU A 197ILE A 152THR A 122PRO A 123 | None | 1.17A | 2ft9A-2w3zA:undetectable | 2ft9A-2w3zA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x47 | MACRODOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF01661(Macro) | 5 | LEU A 287LEU A 301ILE A 267THR A 226ASN A 171 | None | 1.07A | 2ft9A-2x47A:undetectable | 2ft9A-2x47A:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfv | REGULATORY PROTEINSWI6 (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 96ILE A 16PRO A 52ASN A 51LEU A 20 | None | 1.20A | 2ft9A-2xfvA:undetectable | 2ft9A-2xfvA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfv | REGULATORY PROTEINSWI6 (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 96LEU A 94ILE A 16PRO A 52ASN A 51 | None | 1.03A | 2ft9A-2xfvA:undetectable | 2ft9A-2xfvA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvn | ASPERGILLUSFUMIGATUS CHITINASEA1 (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 5 | LEU A 294LEU A 286ILE A 229PRO A 206LEU A 335 | None | 1.27A | 2ft9A-2xvnA:undetectable | 2ft9A-2xvnA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvt | HYPOTHETICAL PROTEINAQ_1956 (Aquifexaeolicus) |
PF14582(Metallophos_3) | 5 | LEU A 165ILE A 208THR A 231ASN A 230LEU A 123 | None | 1.23A | 2ft9A-2yvtA:undetectable | 2ft9A-2yvtA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5i | FLAGELLARBIOSYNTHESIS PROTEINFLHA (Salmonellaenterica) |
PF00771(FHIPEP) | 5 | LEU A 610LEU A 654ILE A 689THR A 632LEU A 620 | None | 1.36A | 2ft9A-3a5iA:undetectable | 2ft9A-3a5iA:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ay3 | NAD-DEPENDENTEPIMERASE/DEHYDRATASE (Chromohalobactersalexigens) |
PF01370(Epimerase) | 5 | LEU A 5LEU A 25ILE A 105ASN A 159LEU A 31 | None | 1.36A | 2ft9A-3ay3A:undetectable | 2ft9A-3ay3A:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2y | METALLOPEPTIDASECONTAININGCO-CATALYTICMETALLOACTIVE SITE (Shewanelladenitrificans) |
PF04952(AstE_AspA) | 5 | LEU A 69ILE A 53PRO A 110ASN A 109LEU A 40 | None | 0.99A | 2ft9A-3b2yA:undetectable | 2ft9A-3b2yA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bcq | ALPHA-CHAINHEMOGLOBIN (Brycon cephalus) |
PF00042(Globin) | 5 | LEU A 130LEU A 106ILE A 10MET A 64LEU A 137 | None | 1.23A | 2ft9A-3bcqA:undetectable | 2ft9A-3bcqA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cob | KINESIN HEAVYCHAIN-LIKE PROTEIN (Solanumtuberosum) |
PF00225(Kinesin) | 5 | LEU A1028LEU A1027ILE A1068THR A 990PRO A 991 | None | 1.29A | 2ft9A-3cobA:undetectable | 2ft9A-3cobA:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg4 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | LEU A 776LEU A 786ILE A 899PRO A 919LEU A 492 | None | 1.36A | 2ft9A-3fg4A:0.1 | 2ft9A-3fg4A:11.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h09 | IMMUNOGLOBULIN A1PROTEASE (Haemophilusinfluenzae) |
PF02395(Peptidase_S6)PF03212(Pertactin) | 5 | LEU A 410LEU A 391ILE A 403PRO A 353ASN A 352 | NoneNoneNoneMLA A2100 (-3.9A)None | 1.18A | 2ft9A-3h09A:undetectable | 2ft9A-3h09A:8.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1z | HALOACIDDEHALOGENASE-LIKEHYDROLASEDOMAIN-CONTAININGPROTEIN 3 (Homo sapiens) |
PF13419(HAD_2) | 5 | LEU A 45LEU A 25ILE A 97PRO A 96LEU A 85 | None | 1.16A | 2ft9A-3k1zA:undetectable | 2ft9A-3k1zA:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kn1 | GOLGI PHOSPHOPROTEIN3 (Homo sapiens) |
PF05719(GPP34) | 5 | LEU A 170LEU A 156THR A 128PRO A 127LEU A 177 | None | 1.11A | 2ft9A-3kn1A:undetectable | 2ft9A-3kn1A:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8q | CELLULOSOMALSCAFFOLDIN ADAPTORPROTEIN B (Acetivibriocellulolyticus) |
PF00963(Cohesin) | 5 | TYR A 95LEU A 76ILE A 69ASN A 27LEU A 98 | None | 1.34A | 2ft9A-3l8qA:undetectable | 2ft9A-3l8qA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3la6 | TYROSINE-PROTEINKINASE WZC (Escherichiacoli) |
PF13614(AAA_31) | 5 | LEU A 574LEU A 573PRO A 502ASN A 501LEU A 640 | None | 1.32A | 2ft9A-3la6A:undetectable | 2ft9A-3la6A:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lx2 | DNA POLYMERASESLIDING CLAMP 2 (Thermococcuskodakarensis) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | LEU A 73LEU A 20THR A 120PRO A 121LEU A 99 | None | 1.12A | 2ft9A-3lx2A:2.0 | 2ft9A-3lx2A:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjp | COVR (Streptococcuspyogenes) |
PF00486(Trans_reg_C) | 5 | LEU A 162LEU A 179ILE A 225ASN A 171ARG A 203 | None | 1.37A | 2ft9A-3rjpA:undetectable | 2ft9A-3rjpA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rkx | BIOTIN-[ACETYL-COA-CARBOXYLASE] LIGASE (Staphylococcusaureus) |
PF03099(BPL_LplA_LipB)PF08279(HTH_11) | 5 | LEU A 249ILE A 71GLN A 69LEU A 213ARG A 241 | None | 1.13A | 2ft9A-3rkxA:undetectable | 2ft9A-3rkxA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tht | ALKYLATED DNA REPAIRPROTEIN ALKB HOMOLOG8 (Homo sapiens) |
PF00076(RRM_1)PF13532(2OG-FeII_Oxy_2) | 5 | LEU A 30LEU A 29PRO A 78ASN A 79LEU A 117 | None | 1.18A | 2ft9A-3thtA:undetectable | 2ft9A-3thtA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ved | DYPB (Rhodococcusjostii) |
PF04261(Dyp_perox) | 5 | LEU A 49LEU A 119THR A 15PRO A 16LEU A 310 | None | 1.17A | 2ft9A-3vedA:undetectable | 2ft9A-3vedA:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vn3 | ANTIFREEZE PROTEIN (Typhulaishikariensis) |
PF11999(DUF3494) | 5 | TYR A 14LEU A 17ILE A 79THR A 76PRO A 75 | EDO A 303 (-4.2A)NoneNoneNoneNone | 1.34A | 2ft9A-3vn3A:undetectable | 2ft9A-3vn3A:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vnp | HYPOTHETICALCONSERVED PROTEIN (Geobacilluskaustophilus) |
PF00132(Hexapep) | 5 | LEU A 63LEU A 85ILE A 30THR A 34ASN A 53 | None | 1.16A | 2ft9A-3vnpA:undetectable | 2ft9A-3vnpA:23.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vr5 | V-TYPE SODIUM ATPASECATALYTIC SUBUNIT A (Enterococcushirae) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N)PF16886(ATP-synt_ab_Xtn) | 5 | TYR A 366LEU A 362LEU A 358ILE A 307LEU A 406 | None | 1.32A | 2ft9A-3vr5A:undetectable | 2ft9A-3vr5A:13.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vvd | AMINO ACID ABCTRANSPORTER, BINDINGPROTEIN (Thermusthermophilus) |
PF00497(SBP_bac_3) | 5 | LEU A 64LEU A 67ILE A 81PRO A 94ASN A 93 | None | 1.31A | 2ft9A-3vvdA:undetectable | 2ft9A-3vvdA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vyl | L-RIBULOSE3-EPIMERASE (Mesorhizobiumloti) |
PF01261(AP_endonuc_2) | 5 | LEU A 59LEU A 57ILE A 6ASN A 266LEU A 98 | None | 1.37A | 2ft9A-3vylA:undetectable | 2ft9A-3vylA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wp9 | ICE-BINDING PROTEIN (Colwellia sp.SLW05) |
PF11999(DUF3494) | 5 | LEU A 45ILE A 39PRO A 38MET A 55LEU A 209 | None | 1.09A | 2ft9A-3wp9A:undetectable | 2ft9A-3wp9A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bfr | PHOSPHATIDYLINOSITOL4,5-BISPHOSPHATE3-KINASE CATALYTIC SSUBUNIT BETA ISOFORM (Mus musculus) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka)PF00792(PI3K_C2)PF00794(PI3K_rbd) | 5 | LEU A 936LEU A 909PRO A 540ASN A 992LEU A1006 | None | 1.23A | 2ft9A-4bfrA:undetectable | 2ft9A-4bfrA:8.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxw | FACTOR XA (Pseudonajatextilis) |
PF00089(Trypsin)PF14670(FXa_inhibition) | 5 | LEU A 201LEU A 286ILE A 266THR A 396ASN A 344 | None | 1.25A | 2ft9A-4bxwA:undetectable | 2ft9A-4bxwA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4by6 | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1 (Saccharomycescerevisiae) |
PF04054(Not1) | 5 | LEU A1972LEU A1969ILE A1908PRO A1892ASN A1895 | None | 1.34A | 2ft9A-4by6A:undetectable | 2ft9A-4by6A:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d72 | GLYCOSIDE HYDROLASE (Streptococcuspneumoniae) |
PF08306(Glyco_hydro_98M)PF08307(Glyco_hydro_98C) | 5 | LEU A1001LEU A 895ILE A 991THR A 950ASN A 901 | None | 1.18A | 2ft9A-4d72A:3.2 | 2ft9A-4d72A:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d72 | GLYCOSIDE HYDROLASE (Streptococcuspneumoniae) |
PF08306(Glyco_hydro_98M)PF08307(Glyco_hydro_98C) | 5 | LEU A1001LEU A 895ILE A 991THR A 950MET A 876 | None | 1.26A | 2ft9A-4d72A:3.2 | 2ft9A-4d72A:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4db3 | N-ACETYL-D-GLUCOSAMINE KINASE (Vibriovulnificus) |
PF00480(ROK) | 5 | LEU A 130LEU A 255ILE A 282PRO A 266LEU A 185 | None | 1.30A | 2ft9A-4db3A:undetectable | 2ft9A-4db3A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emk | U6 SNRNA-ASSOCIATEDSM-LIKE PROTEIN LSM5U6 SNRNA-ASSOCIATEDSM-LIKE PROTEIN LSM7 (Schizosaccharomycespombe;Schizosaccharomycespombe) |
PF01423(LSM)PF01423(LSM) | 5 | LEU A 44LEU A 65ILE A 11ASN C 58MET A 23 | None | 1.01A | 2ft9A-4emkA:undetectable | 2ft9A-4emkA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3p | GLUTAMINE-BINDINGPERIPLASMIC PROTEIN (Burkholderiapseudomallei) |
PF00497(SBP_bac_3) | 5 | LEU A 169ILE A 135PRO A 153ASN A 131ARG A 157 | None | 1.05A | 2ft9A-4f3pA:undetectable | 2ft9A-4f3pA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f52 | CULLIN-1 (Homo sapiens) |
PF00888(Cullin) | 5 | LEU A 643LEU A 649ILE A 631THR A 629LEU A 590 | None | 1.31A | 2ft9A-4f52A:undetectable | 2ft9A-4f52A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ffk | SUPEROXIDE DISMUTASE (Acidilobussaccharovorans) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 5 | LEU A 94LEU A 91ILE A 172PRO A 150ASN A 170 | None | 0.91A | 2ft9A-4ffkA:undetectable | 2ft9A-4ffkA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h62 | MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 17 (Saccharomycescerevisiae) |
PF10156(Med17) | 5 | LEU Q 478LEU Q 479ILE Q 435MET Q 411LEU Q 508 | None | 1.10A | 2ft9A-4h62Q:3.7 | 2ft9A-4h62Q:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i93 | PROBABLESERINE/THREONINE-PROTEIN KINASEAT5G41260 (Arabidopsisthaliana) |
PF07714(Pkinase_Tyr) | 5 | LEU A 293ILE A 235PRO A 303ASN A 302LEU A 246 | None | 1.33A | 2ft9A-4i93A:undetectable | 2ft9A-4i93A:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j7q | PHOSPHATIDYLINOSITOLTRANSFER PROTEINPDR16 (Saccharomycescerevisiae) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 5 | LEU A 237LEU A 195ILE A 199PRO A 162GLN A 145 | B7N A 401 (-3.9A)B7N A 401 ( 4.9A)NoneNoneNone | 1.27A | 2ft9A-4j7qA:undetectable | 2ft9A-4j7qA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lk3 | UDP-GLUCURONIC ACIDDECARBOXYLASE 1 (Homo sapiens) |
PF16363(GDP_Man_Dehyd) | 5 | LEU A 312ILE A 365PRO A 326ASN A 325GLN A 300 | None | 1.19A | 2ft9A-4lk3A:undetectable | 2ft9A-4lk3A:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pqh | GLUTATHIONETRANSFERASE LAMBDA1 (Populustrichocarpa) |
PF13410(GST_C_2)PF13417(GST_N_3) | 5 | ILE A 44THR A 217ASN A 215GLN A 216LEU A 82 | None | 1.31A | 2ft9A-4pqhA:undetectable | 2ft9A-4pqhA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pw8 | TRYPTOPHAN2,3-DIOXYGENASE (Homo sapiens) |
PF03301(Trp_dioxygenase) | 5 | LEU A 365LEU A 368THR A 212PRO A 213LEU A 202 | None | 1.31A | 2ft9A-4pw8A:undetectable | 2ft9A-4pw8A:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgj | CALCIUM-DEPENDENTPROTEIN KINASE 4 (Plasmodiumfalciparum) |
PF00069(Pkinase)PF13499(EF-hand_7) | 5 | LEU A 260LEU A 264ILE A 328THR A 332LEU A 155 | None | 1.37A | 2ft9A-4rgjA:undetectable | 2ft9A-4rgjA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s2t | PROTEIN APP-1 (Caenorhabditiselegans) |
PF00557(Peptidase_M24)PF01321(Creatinase_N)PF16188(Peptidase_M24_C)PF16189(Creatinase_N_2) | 5 | LEU P 573LEU P 574ILE P 439PRO P 434LEU P 474 | None | 1.29A | 2ft9A-4s2tP:undetectable | 2ft9A-4s2tP:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u06 | LIC10831 (Leptospirainterrogans) |
PF12799(LRR_4)PF13855(LRR_8) | 5 | LEU A 209LEU A 229ILE A 180PRO A 177ASN A 178 | NoneNoneNoneNone ZN A 403 (-2.6A) | 1.24A | 2ft9A-4u06A:undetectable | 2ft9A-4u06A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ufs | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 5 (Homo sapiens) |
PF00560(LRR_1)PF01462(LRRNT)PF13855(LRR_8) | 5 | LEU A 97LEU A 95PRO A 83ASN A 84LEU A 126 | None | 1.15A | 2ft9A-4ufsA:undetectable | 2ft9A-4ufsA:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wpm | MRNA EXPORT PROTEIN (Chaetomiumthermophilum) |
no annotation | 5 | LEU A 123LEU A 136ILE A 140PRO A 181LEU A 171 | None | 1.35A | 2ft9A-4wpmA:undetectable | 2ft9A-4wpmA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xrt | STFQAROMATASE/CYCLASE (Streptomycessteffisburgensis) |
PF03364(Polyketide_cyc) | 5 | TYR A 283LEU A 271THR A 206PRO A 207LEU A 237 | None | 1.22A | 2ft9A-4xrtA:2.7 | 2ft9A-4xrtA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yir | UV EXCISION REPAIRPROTEIN RAD23 (Saccharomycescerevisiae) |
PF09280(XPC-binding) | 5 | LEU X 265LEU X 262ILE X 294PRO X 298ASN X 297 | None | 1.36A | 2ft9A-4yirX:undetectable | 2ft9A-4yirX:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zmi | TELOMERE LENGTHREGULATOR TAZ1 (Schizosaccharomycespombe) |
PF08558(TRF) | 5 | LEU A 251LEU A 254ILE A 326ASN A 328LEU A 246 | None | 1.13A | 2ft9A-4zmiA:undetectable | 2ft9A-4zmiA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6f | GATING RING OFPOTASSIUM CHANNELSUBFAMILY T MEMBER 1 (Gallus gallus) |
PF03493(BK_channel_a) | 5 | LEU C 512LEU C 508ILE C 575ASN C 588LEU C 951 | None | 1.15A | 2ft9A-5a6fC:undetectable | 2ft9A-5a6fC:11.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5h | ANTIFREEZE PROTEIN (Typhulaishikariensis) |
PF11999(DUF3494) | 5 | TYR A 14LEU A 17ILE A 79THR A 76PRO A 75 | None | 1.33A | 2ft9A-5b5hA:undetectable | 2ft9A-5b5hA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bnd | ABC TRANSPORTER,ATP-BINDING PROTEIN (Staphylococcusepidermidis) |
no annotation | 5 | LEU A 458LEU A 420ILE A 448PRO A 464LEU A 357 | None | 1.32A | 2ft9A-5bndA:undetectable | 2ft9A-5bndA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bnd | ABC TRANSPORTER,ATP-BINDING PROTEIN (Staphylococcusepidermidis) |
no annotation | 5 | LEU A 458LEU A 420PRO A 447ASN A 408LEU A 357 | None | 1.35A | 2ft9A-5bndA:undetectable | 2ft9A-5bndA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c78 | ATP-DRIVEN FLIPPASEPGLK (Campylobacterjejuni) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | TYR A 93LEU A 97PRO A 305ASN A 308LEU A 21 | None | 1.35A | 2ft9A-5c78A:undetectable | 2ft9A-5c78A:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c8w | CGMP-DEPENDENTPROTEIN KINASE 2 (Homo sapiens) |
PF00027(cNMP_binding) | 5 | LEU A 169LEU A 163ILE A 236ASN A 203MET A 184 | NoneNoneNoneMLA A 301 (-4.9A)None | 1.36A | 2ft9A-5c8wA:undetectable | 2ft9A-5c8wA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5goo | ALKALINE INVERTASE (Nostoc sp. PCC7120) |
PF12899(Glyco_hydro_100) | 5 | LEU A 136ILE A 200PRO A 197MET A 311LEU A 232 | None | 1.28A | 2ft9A-5gooA:undetectable | 2ft9A-5gooA:13.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hiw | CYTOCHROME P450CYP260B1 (Sorangiumcellulosum) |
PF00067(p450) | 5 | LEU A 362LEU A 356ILE A 387PRO A 384ASN A 239 | None | 1.13A | 2ft9A-5hiwA:undetectable | 2ft9A-5hiwA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m85 | SENSORY TRANSDUCTIONHISTIDINE KINASE (Synechocystissp. PCC 6803) |
no annotation | 5 | LEU A 441PRO A 468ASN A 467LEU A 591ARG A 594 | None | 1.37A | 2ft9A-5m85A:undetectable | 2ft9A-5m85A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mea | CELL DIVISION CYCLEPROTEIN CDT1 (Saccharomycescerevisiae) |
no annotation | 5 | TYR A 371LEU A 363THR A 323MET A 351LEU A 340 | None | 1.37A | 2ft9A-5meaA:1.5 | 2ft9A-5meaA:12.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v6t | PLEXIN-D1 (Mus musculus) |
PF08337(Plexin_cytopl) | 5 | LEU A1795LEU A1776ILE A1785PRO A1347LEU A1714 | None | 1.32A | 2ft9A-5v6tA:undetectable | 2ft9A-5v6tA:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v72 | NADPH-DEPENDENTGLYOXYLATE/HYDROXYPYRUVATE REDUCTASE (Sinorhizobiummeliloti) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 219LEU A 216ILE A 226THR A 111ARG A 143 | None | 1.32A | 2ft9A-5v72A:undetectable | 2ft9A-5v72A:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z95 | - (-) |
no annotation | 5 | LEU A 202LEU A 232PRO A 221GLN A 213MET A 117 | NoneNoneGOL A 304 ( 4.9A)NoneNone | 1.13A | 2ft9A-5z95A:undetectable | 2ft9A-5z95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zya | SPLICING FACTOR 3BSUBUNIT 1 (Homo sapiens) |
no annotation | 5 | LEU C 560LEU C 600PRO C 530ASN C 533ARG C 524 | None | 1.26A | 2ft9A-5zyaC:undetectable | 2ft9A-5zyaC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6an0 | HISTIDINOLDEHYDROGENASE (Elizabethkingiaanophelis) |
PF00815(Histidinol_dh) | 5 | LEU A 278ILE A 304PRO A 7ASN A 6LEU A 299 | NoneNoneNoneIOD A 509 (-4.1A)None | 1.29A | 2ft9A-6an0A:undetectable | 2ft9A-6an0A:14.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoj | PROTEIN CFT1 (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 78LEU A 76THR A 826ASN A 824LEU A 102 | None | 1.34A | 2ft9A-6eojA:undetectable | 2ft9A-6eojA:6.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g72 | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN2 (Mus musculus) |
no annotation | 5 | LEU N 99LEU N 102THR N 201ASN N 204LEU N 148 | None | 1.28A | 2ft9A-6g72N:undetectable | 2ft9A-6g72N:undetectable |