SIMILAR PATTERNS OF AMINO ACIDS FOR 2FT9_A_CHDA130_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ciy | CRYIA(A) (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | PHE A 247VAL A 162ILE A 63SER A 39ILE A 64 | None | 1.10A | 2ft9A-1ciyA:0.0 | 2ft9A-1ciyA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h65 | CHLOROPLAST OUTERENVELOPE PROTEINOEP34 (Pisum sativum) |
PF04548(AIG1) | 5 | VAL A 141ILE A 120ILE A 153VAL A 252LEU A 108 | None | 1.27A | 2ft9A-1h65A:0.0 | 2ft9A-1h65A:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks5 | ENDOGLUCANASE A (Aspergillusniger) |
PF01670(Glyco_hydro_12) | 5 | PHE A 68VAL A 66PHE A 163ILE A 119LEU A 196 | None | 1.06A | 2ft9A-1ks5A:undetectable | 2ft9A-1ks5A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfd | H57 FAB (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL F 121ASN F 162ILE F 205ILE F 225VAL F 193 | None | 1.16A | 2ft9A-1nfdF:0.4 | 2ft9A-1nfdF:18.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1o1u | GASTROTROPIN (Homo sapiens) |
PF14651(Lipocalin_7) | 5 | PHE A 17ASN A 61PHE A 63ILE A 71VAL A 83 | None | 1.01A | 2ft9A-1o1uA:17.6 | 2ft9A-1o1uA:38.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p6p | FATTY ACID-BINDINGPROTEIN, LIVER (Rhinellaarenarum) |
PF14651(Lipocalin_7) | 6 | PHE A 17VAL A 21ASN A 60PHE A 62ILE A 70HIS A 98 | None | 0.96A | 2ft9A-1p6pA:20.6 | 2ft9A-1p6pA:73.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1poj | ISOASPARTYLDIPEPTIDASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | ASN A 232PHE A 238ILE A 253SER A 255LEU A 317 | None | 1.12A | 2ft9A-1pojA:0.2 | 2ft9A-1pojA:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5d | P450 EPOXIDASE (Sorangiumcellulosum) |
PF00067(p450) | 5 | VAL A 106PHE A 172ILE A 252ILE A 251LEU A 244 | NoneNoneNoneHEM A 440 (-4.5A)None | 1.26A | 2ft9A-1q5dA:undetectable | 2ft9A-1q5dA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwk | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C1 (Caenorhabditiselegans) |
PF00248(Aldo_ket_red) | 5 | PHE A 312PHE A 138SER A 174ILE A 160VAL A 134 | None | 1.21A | 2ft9A-1qwkA:undetectable | 2ft9A-1qwkA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tq4 | INTERFERON-INDUCIBLEGTPASE (Mus musculus) |
PF05049(IIGP) | 5 | PHE A 124VAL A 72ILE A 248VAL A 270LEU A 89 | None | 1.17A | 2ft9A-1tq4A:undetectable | 2ft9A-1tq4A:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w8a | SLIT PROTEIN (Drosophilamelanogaster) |
PF00560(LRR_1)PF01462(LRRNT)PF01463(LRRCT)PF13855(LRR_8) | 5 | ASN A 677ILE A 655ILE A 631VAL A 658LEU A 648 | None | 1.20A | 2ft9A-1w8aA:undetectable | 2ft9A-1w8aA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wom | SIGMA FACTOR SIGBREGULATION PROTEINRSBQ (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 5 | PHE A 50CYH A 82VAL A 78PHE A 113LEU A 116 | None | 1.23A | 2ft9A-1womA:undetectable | 2ft9A-1womA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xqs | HSPBP1 PROTEIN (Homo sapiens) |
PF08609(Fes1) | 5 | PHE A 226VAL A 216PHE A 288VAL A 292LEU A 235 | None | 1.20A | 2ft9A-1xqsA:undetectable | 2ft9A-1xqsA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2btm | PROTEIN(TRIOSEPHOSPHATEISOMERASE) (Geobacillusstearothermophilus) |
PF00121(TIM) | 5 | VAL A 77ASN A 8ILE A 91VAL A 38LEU A 46 | NonePGA A 301 (-4.6A)NoneNoneNone | 1.28A | 2ft9A-2btmA:undetectable | 2ft9A-2btmA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cf5 | CINNAMYL ALCOHOLDEHYDROGENASE (Arabidopsisthaliana) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | VAL A 76ASN A 354ILE A 41VAL A 66LEU A 29 | None | 1.15A | 2ft9A-2cf5A:undetectable | 2ft9A-2cf5A:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e8b | PROBABLEMOLYBDOPTERIN-GUANINE DINUCLEOTIDEBIOSYNTHESIS PROTEINA (Aquifexaeolicus) |
PF12804(NTP_transf_3) | 5 | PHE A 101VAL A 118ASN A 184VAL A 42LEU A 103 | None | 1.17A | 2ft9A-2e8bA:undetectable | 2ft9A-2e8bA:23.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eo5 | 419AA LONGHYPOTHETICALAMINOTRANSFERASE (Sulfurisphaeratokodaii) |
PF00202(Aminotran_3) | 5 | VAL A 254ASN A 81SER A 110ILE A 290CYH A 317 | PLP A1001 ( 4.3A)NoneNoneNoneNone | 1.19A | 2ft9A-2eo5A:undetectable | 2ft9A-2eo5A:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fbv | WERNER SYNDROMEHELICASE (Homo sapiens) |
PF01612(DNA_pol_A_exo1) | 5 | VAL A 133PHE A 151ILE A 153VAL A 97LEU A 102 | None | 1.25A | 2ft9A-2fbvA:undetectable | 2ft9A-2fbvA:20.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 7 | ASN A 60PHE A 62ILE A 70SER A 72ILE A 78CYH A 80VAL A 82 | NoneNoneNoneOLA A 130 ( 3.8A)NoneNoneNone | 0.93A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 10 | PHE A 17VAL A 21ASN A 60PHE A 62ILE A 70CYH A 80VAL A 82PHE A 96HIS A 98LEU A 111 | NoneOLA A 130 ( 4.9A)NoneNoneNoneNoneNoneOLA A 130 ( 4.2A)OLA A 130 ( 4.8A)None | 0.61A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 10 | PHE A 17VAL A 21ASN A 60PHE A 62ILE A 70ILE A 78CYH A 80VAL A 82PHE A 96HIS A 98 | NoneOLA A 130 ( 4.9A)NoneNoneNoneNoneNoneNoneOLA A 130 ( 4.2A)OLA A 130 ( 4.8A) | 0.59A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ftb | FATTY ACID-BINDINGPROTEIN 2, LIVER (Ambystomamexicanum) |
PF14651(Lipocalin_7) | 6 | VAL A 113ASN A 60PHE A 62ILE A 70SER A 72ILE A 78 | NoneNoneNoneNoneOLA A 130 ( 3.8A)None | 1.17A | 2ft9A-2ftbA:23.0 | 2ft9A-2ftbA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gaf | POLY(A) POLYMERASECATALYTIC SUBUNIT (Vaccinia virus) |
PF03296(Pox_polyA_pol)PF12629(Pox_polyA_pol_C)PF12630(Pox_polyA_pol_N) | 5 | PHE D 52VAL D 56ASN D 228ILE D 229LEU D 104 | None | 1.28A | 2ft9A-2gafD:undetectable | 2ft9A-2gafD:13.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jty | TYPE-1 FIMBRIALPROTEIN, A CHAIN (Escherichiacoli) |
PF00419(Fimbrial) | 5 | PHE A 177VAL A 32ILE A 131ILE A 56PHE A 154 | None | 1.26A | 2ft9A-2jtyA:undetectable | 2ft9A-2jtyA:17.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2lba | BABP PROTEIN (Gallus gallus) |
PF14651(Lipocalin_7) | 5 | ASN A 61PHE A 63VAL A 83PHE A 94HIS A 99 | CHO A 201 ( 3.5A)CHO A 201 (-3.1A)CHO A 201 ( 4.0A)CHO A 201 (-2.9A)CHO A 201 (-3.0A) | 0.96A | 2ft9A-2lbaA:18.8 | 2ft9A-2lbaA:38.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2lba | BABP PROTEIN (Gallus gallus) |
PF14651(Lipocalin_7) | 5 | PHE A 17ASN A 61PHE A 63VAL A 83HIS A 99 | CHO A 200 ( 4.3A)CHO A 201 ( 3.5A)CHO A 201 (-3.1A)CHO A 201 ( 4.0A)CHO A 201 (-3.0A) | 0.72A | 2ft9A-2lbaA:18.8 | 2ft9A-2lbaA:38.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pkg | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A65 KDA REGULATORYSUBUNIT A ALPHAISOFORM (Homo sapiens) |
PF02985(HEAT)PF13646(HEAT_2) | 5 | ILE A 326ILE A 322CYH A 310VAL A 306LEU A 365 | None | 1.05A | 2ft9A-2pkgA:undetectable | 2ft9A-2pkgA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pzz | UPF0201 PROTEINMJ1564 (Methanocaldococcusjannaschii) |
PF01877(RNA_binding) | 5 | PHE A 27VAL A 4ILE A 120ILE A 119LEU A 54 | None | 1.25A | 2ft9A-2pzzA:undetectable | 2ft9A-2pzzA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qgu | PROBABLE SIGNALPEPTIDE PROTEIN (Ralstoniasolanacearum) |
PF05494(MlaC) | 5 | VAL A 64ILE A 168ILE A 166VAL A 148LEU A 113 | PEF A 301 ( 4.8A)PEF A 301 (-4.3A)PEF A 301 ( 4.0A)NoneNone | 1.08A | 2ft9A-2qguA:undetectable | 2ft9A-2qguA:17.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qo4 | LIVER-BASIC FATTYACID BINDING PROTEIN (Danio rerio) |
PF14651(Lipocalin_7) | 7 | PHE A 17ASN A 60PHE A 62ILE A 70VAL A 82HIS A 98LEU A 111 | NoneIPA A 141 ( 4.7A)IPA A 142 ( 4.4A)IPA A 141 ( 4.5A)NoneIPA A 140 (-3.7A)CHD A 130 ( 4.9A) | 1.05A | 2ft9A-2qo4A:20.7 | 2ft9A-2qo4A:69.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xcz | POSSIBLE ATLS1-LIKELIGHT-INDUCIBLEPROTEIN (Prochlorococcusmarinus) |
PF01187(MIF) | 5 | ILE A 94ILE A 89CYH A 57VAL A 59LEU A 18 | None | 1.08A | 2ft9A-2xczA:undetectable | 2ft9A-2xczA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfv | REGULATORY PROTEINSWI6 (Saccharomycescerevisiae) |
no annotation | 5 | PHE A 55ILE A 82CYH A 87PHE A 34HIS A 33 | None | 1.28A | 2ft9A-2xfvA:undetectable | 2ft9A-2xfvA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yyz | SUGAR ABCTRANSPORTER,ATP-BINDING PROTEIN (Thermotogamaritima) |
PF00005(ABC_tran)PF08402(TOBE_2) | 5 | PHE A 207VAL A 22ILE A 60VAL A 154LEU A 34 | None | 1.20A | 2ft9A-2yyzA:undetectable | 2ft9A-2yyzA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aag | GENERALGLYCOSYLATIONPATHWAY PROTEIN (Campylobacterjejuni) |
PF02516(STT3) | 5 | PHE A 709PHE A 659ILE A 637ILE A 640PHE A 687 | NoneNoneNoneMLY A 641 ( 3.5A)MLY A 707 ( 4.4A) | 1.28A | 2ft9A-3aagA:undetectable | 2ft9A-3aagA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ega | PROTEIN PELLINOHOMOLOG 2 (Homo sapiens) |
PF04710(Pellino) | 5 | ILE A 246SER A 244ILE A 155CYH A 141VAL A 104 | None | 1.14A | 2ft9A-3egaA:undetectable | 2ft9A-3egaA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jbz | SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08771(FRB_dom) | 5 | PHE A1798ASN A2494ILE A2498ILE A2501LEU A1802 | None | 1.27A | 2ft9A-3jbzA:undetectable | 2ft9A-3jbzA:7.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kf3 | INVERTASE (Schwanniomycesoccidentalis) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 5 | VAL A 447PHE A 391ILE A 415ILE A 427PHE A 501 | None | 1.24A | 2ft9A-3kf3A:undetectable | 2ft9A-3kf3A:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3llx | PREDICTED AMINO ACIDALDOLASE OR RACEMASE (Idiomarinaloihiensis) |
PF01168(Ala_racemase_N)PF14031(D-ser_dehydrat) | 5 | PHE A 226ILE A 247SER A 175PHE A 222HIS A 221 | NoneNoneNoneNoneEDO A 384 (-4.5A) | 1.17A | 2ft9A-3llxA:undetectable | 2ft9A-3llxA:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3on4 | TRANSCRIPTIONALREGULATOR, TETRFAMILY (Legionellapneumophila) |
PF00440(TetR_N) | 5 | VAL A 138ILE A 157ILE A 156PHE A 88LEU A 70 | None | 1.29A | 2ft9A-3on4A:undetectable | 2ft9A-3on4A:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pta | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC) | 5 | VAL A1298PHE A1243SER A1273CYH A1226VAL A1248 | None | 1.28A | 2ft9A-3ptaA:undetectable | 2ft9A-3ptaA:8.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqg | METHYL-COENZYME MREDUCTASE, GAMMASUBUNIT (unculturedarchaeon) |
PF02240(MCR_gamma) | 5 | VAL C 138ILE C 122ILE C 123HIS C 42LEU C 40 | None | 1.29A | 2ft9A-3sqgC:undetectable | 2ft9A-3sqgC:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vis | ESTERASE (Thermobifidaalba) |
PF12740(Chlorophyllase2) | 5 | VAL A 220ASN A 254ILE A 257ILE A 210HIS A 168 | None | 1.02A | 2ft9A-3visA:undetectable | 2ft9A-3visA:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vkg | DYNEIN HEAVY CHAIN,CYTOPLASMIC (Dictyosteliumdiscoideum) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | PHE A2701VAL A2759ILE A2786CYH A2718LEU A2699 | None | 1.22A | 2ft9A-3vkgA:undetectable | 2ft9A-3vkgA:3.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vva | ALTERNATIVE OXIDASE,MITOCHONDRIAL (Trypanosomabrucei) |
PF01786(AOX) | 5 | VAL A 242ILE A 259ILE A 262VAL A 115PHE A 169 | None | 1.28A | 2ft9A-3vvaA:undetectable | 2ft9A-3vvaA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zfc | CHROMOSOME-ASSOCIATED KINESIN KIF4 (Mus musculus) |
PF00225(Kinesin) | 5 | PHE A 65VAL A 114PHE A 134ILE A 221ILE A 219 | None | 1.10A | 2ft9A-3zfcA:undetectable | 2ft9A-3zfcA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyi | LEUCINE-RICHREPEAT-CONTAININGPROTEIN 4 (Homo sapiens) |
PF07679(I-set)PF13855(LRR_8) | 5 | PHE A 230ILE A 257VAL A 249PHE A 262LEU A 265 | None | 1.28A | 2ft9A-3zyiA:undetectable | 2ft9A-3zyiA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a01 | PROTONPYROPHOSPHATASE (Vigna radiata) |
PF03030(H_PPase) | 5 | PHE A 474ILE A 565SER A 561VAL A 575PHE A 556 | None | 1.19A | 2ft9A-4a01A:undetectable | 2ft9A-4a01A:10.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4agu | CYCLIN-DEPENDENTKINASE-LIKE 1 (Homo sapiens) |
PF00069(Pkinase) | 5 | PHE A 192VAL A 103ILE A 290HIS A 284LEU A 263 | None | 1.18A | 2ft9A-4aguA:undetectable | 2ft9A-4aguA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ang | COAT PROTEIN (Pseudomonasphage PRR1) |
PF01819(Levi_coat) | 5 | PHE A 91ILE A 47VAL A 89PHE A 45LEU A 8 | None | 1.21A | 2ft9A-4angA:3.6 | 2ft9A-4angA:28.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4arx | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | PHE A 247VAL A 162ILE A 63SER A 39ILE A 64 | None | 1.11A | 2ft9A-4arxA:undetectable | 2ft9A-4arxA:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bn2 | KINESIN-LIKE PROTEINKIF15 (Homo sapiens) |
PF00225(Kinesin) | 5 | PHE A 72PHE A 146ILE A 230ILE A 228CYH A 148 | None | 1.09A | 2ft9A-4bn2A:undetectable | 2ft9A-4bn2A:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cg1 | CUTINASE (Thermobifidafusca) |
PF12740(Chlorophyllase2) | 5 | VAL A 181ASN A 215ILE A 218ILE A 171HIS A 129 | None | 1.02A | 2ft9A-4cg1A:undetectable | 2ft9A-4cg1A:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cs5 | PROLIFERATING CELLNUCLEAR ANTIGEN (Litopenaeusvannamei) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | PHE A 144VAL A 225VAL A 45PHE A 215LEU A 212 | None | 1.28A | 2ft9A-4cs5A:undetectable | 2ft9A-4cs5A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 5 | PHE A 303ILE A 238ILE A 203PHE A 314LEU A 372 | None | 1.03A | 2ft9A-4dwsA:undetectable | 2ft9A-4dwsA:12.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e9o | IMV MEMBRANE PROTEIN (Vaccinia virus) |
PF00194(Carb_anhydrase) | 5 | PHE X 185ILE X 119ILE X 91HIS X 95LEU X 63 | None | 1.23A | 2ft9A-4e9oX:1.8 | 2ft9A-4e9oX:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hk1 | PROLIFERATING CELLNUCLEAR ANTIGEN (Drosophilamelanogaster) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | PHE A 144VAL A 225VAL A 45PHE A 215LEU A 212 | None | 1.26A | 2ft9A-4hk1A:undetectable | 2ft9A-4hk1A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6v | AMIDOHYDROLASE 2 (Planctopiruslimnophila) |
PF02614(UxaC) | 5 | VAL A 337PHE A 169VAL A 168PHE A 271LEU A 305 | NoneGOL A 502 (-4.4A)NoneNoneNone | 1.22A | 2ft9A-4i6vA:undetectable | 2ft9A-4i6vA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq7 | HYPOTHETICAL PROTEIN (Bacteroidesuniformis) |
PF11175(DUF2961) | 5 | ILE A 121SER A 135ILE A 137PHE A 141LEU A 156 | None | 1.11A | 2ft9A-4kq7A:undetectable | 2ft9A-4kq7A:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4le4 | BETA-GLUCANASE (Podosporaanserina) |
no annotation | 5 | PHE A 196SER A 147ILE A 135VAL A 183HIS A 181 | None | 0.99A | 2ft9A-4le4A:undetectable | 2ft9A-4le4A:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmo | TELOMERASE REVERSETRANSCRIPTASE (Takifugurubripes) |
PF12009(Telomerase_RBD) | 5 | VAL A 337ILE A 424PHE A 502HIS A 373LEU A 315 | None | 1.24A | 2ft9A-4lmoA:undetectable | 2ft9A-4lmoA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lyy | HYPOXANTHINEPHOSPHORIBOSYLTRANSFERASE (Shewanellapealeana) |
PF00156(Pribosyltran) | 5 | VAL A 46PHE A 151ILE A 152ILE A 169VAL A 172 | None | 1.20A | 2ft9A-4lyyA:undetectable | 2ft9A-4lyyA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m73 | METHYLTRANSFERASEMPPJ (Streptomyceshygroscopicus) |
PF13649(Methyltransf_25) | 5 | PHE A 230VAL A 224ILE A 195VAL A 202LEU A 186 | NoneIOD A 411 ( 4.8A)NoneNoneNone | 1.25A | 2ft9A-4m73A:undetectable | 2ft9A-4m73A:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4obt | TRIOSEPHOSPHATEISOMERASE, CYTOSOLIC (Arabidopsisthaliana) |
PF00121(TIM) | 5 | VAL A 79ASN A 10ILE A 93VAL A 41LEU A 49 | None | 1.25A | 2ft9A-4obtA:undetectable | 2ft9A-4obtA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ohq | TRIOSEPHOSPHATEISOMERASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00121(TIM) | 5 | PHE A 242VAL A 40ILE A 93ILE A 125CYH A 127 | None | 1.28A | 2ft9A-4ohqA:undetectable | 2ft9A-4ohqA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pl2 | DUAL-SPECIFICITY RNAMETHYLTRANSFERASERLMN (Escherichiacoli) |
no annotation | 5 | VAL B 333ILE B 277ILE B 306CYH B 304PHE B 339 | None | 1.16A | 2ft9A-4pl2B:undetectable | 2ft9A-4pl2B:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8j | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | PHE A 247VAL A 162ILE A 63SER A 39ILE A 64 | None | 1.23A | 2ft9A-4w8jA:undetectable | 2ft9A-4w8jA:8.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wer | DIACYLGLYCEROLKINASE CATALYTICDOMAIN PROTEIN (Enterococcusfaecalis) |
PF00781(DAGK_cat) | 5 | ASN A 128ILE A 281ILE A 259VAL A 271LEU A 218 | None | 1.15A | 2ft9A-4werA:undetectable | 2ft9A-4werA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wfi | CUTINASE (Saccharomonosporaviridis) |
PF03403(PAF-AH_p_II) | 5 | VAL A 227ASN A 261ILE A 264ILE A 217HIS A 175 | None | 1.09A | 2ft9A-4wfiA:undetectable | 2ft9A-4wfiA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wqm | TOLUENE-4-MONOOXYGENASE ELECTRONTRANSFER COMPONENT (Pseudomonasmendocina) |
PF00111(Fer2)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | PHE A 103VAL A 128PHE A 118VAL A 163LEU A 185 | NoneNoneNoneFAD A 402 (-3.3A)None | 1.15A | 2ft9A-4wqmA:undetectable | 2ft9A-4wqmA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wyr | ACETYL-COAACETYLTRANSFERASE (Clostridiumacetobutylicum) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | VAL A 241ASN A 316ILE A 344VAL A 337PHE A 178 | None | 1.14A | 2ft9A-4wyrA:undetectable | 2ft9A-4wyrA:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x1v | CD2-ASSOCIATEDPROTEIN (Homo sapiens) |
PF14604(SH3_9) | 5 | VAL A 141ILE A 135ILE A 137CYH A 113VAL A 115 | None | 1.23A | 2ft9A-4x1vA:undetectable | 2ft9A-4x1vA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zcf | RESTRICTIONENDONUCLEASEECOP15I,MODIFICATION SUBUNIT (Escherichiacoli) |
PF01555(N6_N4_Mtase) | 5 | PHE A 29ILE A 44ILE A 43PHE A 25LEU A 21 | None | 1.12A | 2ft9A-4zcfA:undetectable | 2ft9A-4zcfA:11.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a0t | RIBONUCLEASE J (Streptomycescoelicolor) |
PF00753(Lactamase_B)PF07521(RMMBL) | 5 | VAL A 149ILE A 161CYH A 144VAL A 139PHE A 146 | None | 1.25A | 2ft9A-5a0tA:undetectable | 2ft9A-5a0tA:12.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aor | DOSAGE COMPENSATIONREGULATOR (Drosophilamelanogaster) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 5 | PHE A1077VAL A1143ILE A1129CYH A 980LEU A1003 | None | 1.18A | 2ft9A-5aorA:undetectable | 2ft9A-5aorA:7.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA, K-ATPASE ALPHASUBUNIT (Squalusacanthias) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF13246(Cation_ATPase) | 5 | ILE A 373SER A 375CYH A 606VAL A 762LEU A 750 | None | 1.23A | 2ft9A-5aw4A:2.6 | 2ft9A-5aw4A:8.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csl | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2)PF08326(ACC_central) | 5 | PHE A1003PHE A 802ILE A 830VAL A 806PHE A 926 | None | 1.21A | 2ft9A-5cslA:undetectable | 2ft9A-5cslA:4.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eco | GLUTATHIONES-TRANSFERASE U20 (Arabidopsisthaliana) |
PF02798(GST_N)PF13410(GST_C_2) | 5 | PHE B 145ILE B 175SER B 179ILE B 183LEU B 157 | None | 1.04A | 2ft9A-5ecoB:undetectable | 2ft9A-5ecoB:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5erg | TRNA(ADENINE(58)-N(1))-METHYLTRANSFERASECATALYTIC SUBUNITTRM61 (Saccharomycescerevisiae) |
PF08704(GCD14) | 5 | PHE B 39ILE B 51SER B 58ILE B 13VAL B 31 | None | 1.17A | 2ft9A-5ergB:undetectable | 2ft9A-5ergB:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g47 | SFTSV GC (SFTSphlebovirus) |
PF07245(Phlebovirus_G2) | 5 | PHE A 607VAL A 760ILE A 734VAL A 597LEU A 605 | None | 1.24A | 2ft9A-5g47A:undetectable | 2ft9A-5g47A:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gqr | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE TDR (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | PHE B 237ASN B 183PHE B 158ILE B 206LEU B 213 | None | 1.18A | 2ft9A-5gqrB:undetectable | 2ft9A-5gqrB:11.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdt | SISTER CHROMATIDCOHESION PROTEINPDS5 HOMOLOG B (Homo sapiens) |
no annotation | 5 | ILE A1076SER A1078ILE A1075VAL A1044LEU A1112 | None | 1.05A | 2ft9A-5hdtA:undetectable | 2ft9A-5hdtA:7.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hp6 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF13385(Laminin_G_3)PF16369(GH43_C) | 5 | VAL A 438ILE A 508ILE A 506VAL A 480PHE A 532 | None | 1.20A | 2ft9A-5hp6A:undetectable | 2ft9A-5hp6A:10.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hqb | ALPHA-GLUCOSIDASE (Pseudoalteromonassp. K8) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 5 | PHE A 106VAL A 104ILE A 44ILE A 31LEU A 57 | None | 1.28A | 2ft9A-5hqbA:2.4 | 2ft9A-5hqbA:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hqb | ALPHA-GLUCOSIDASE (Pseudoalteromonassp. K8) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 5 | PHE A 106VAL A 104ILE A 44PHE A 129LEU A 57 | None | 1.19A | 2ft9A-5hqbA:2.4 | 2ft9A-5hqbA:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hr6 | RLMN METHYLASE (Escherichiacoli) |
PF04055(Radical_SAM) | 5 | VAL A 333ILE A 277ILE A 306CYH A 304PHE A 339 | None | 1.15A | 2ft9A-5hr6A:undetectable | 2ft9A-5hr6A:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibx | TRIOSEPHOSPHATEISOMERASE (Streptococcuspneumoniae) |
PF00121(TIM) | 5 | ILE A 165SER A 163ILE A 126CYH A 128VAL A 144 | None | 1.25A | 2ft9A-5ibxA:undetectable | 2ft9A-5ibxA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iw9 | BASEPLATE WEDGEPROTEIN GP25 (Escherichiavirus T4) |
PF04965(GPW_gp25) | 5 | ILE A 40SER A 35ILE A 39CYH A 55LEU A 91 | None | 1.29A | 2ft9A-5iw9A:undetectable | 2ft9A-5iw9A:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1l | TOXR-ACTIVATED GENE(TAGE)TOXR-ACTIVATED GENE(TAGE) (Helicobacterpylori;Helicobacterpylori) |
PF01551(Peptidase_M23)PF01551(Peptidase_M23) | 5 | PHE B 207VAL B 289ASN A 141PHE A 267VAL A 255 | None | 1.17A | 2ft9A-5j1lB:undetectable | 2ft9A-5j1lB:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbg | LGP2 (Gallus gallus) |
PF00271(Helicase_C)PF04851(ResIII)PF11648(RIG-I_C-RD) | 5 | ILE A 445CYH A 448VAL A 451PHE A 425LEU A 401 | None | 1.02A | 2ft9A-5jbgA:undetectable | 2ft9A-5jbgA:10.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE ALPHASUBUNIT (Aromatoleumaromaticum) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 5 | VAL b 75SER b 243ILE b 247VAL b 303LEU b 108 | None | 1.11A | 2ft9A-5l9wb:undetectable | 2ft9A-5l9wb:12.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n4l | CERULOPLASMIN (Rattusnorvegicus) |
no annotation | 5 | PHE A 413ILE A 441ILE A 433VAL A 351HIS A 353 | None | 1.27A | 2ft9A-5n4lA:undetectable | 2ft9A-5n4lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5th3 | R-SWAI PROTEIN (Staphylococcuswarneri) |
no annotation | 5 | PHE A 81ILE A 90ILE A 92CYH A 79PHE A 48 | None | 1.22A | 2ft9A-5th3A:undetectable | 2ft9A-5th3A:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u39 | UDP-3-O-ACYL-N-ACETYLGLUCOSAMINEDEACETYLASE (Pseudomonasaeruginosa) |
PF03331(LpxC) | 5 | PHE A 181VAL A 111ILE A 102HIS A 237LEU A 240 | NoneNoneNone ZN A 501 ( 3.2A)None | 1.28A | 2ft9A-5u39A:undetectable | 2ft9A-5u39A:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5usl | IMV MEMBRANE PROTEIN (Vaccinia virus) |
no annotation | 5 | PHE X 185ILE X 119ILE X 91HIS X 95LEU X 63 | None | 1.20A | 2ft9A-5uslX:1.9 | 2ft9A-5uslX:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w81 | CYSTIC FIBROSISTRANSMEMBRANECONDUCTANCEREGULATOR (Danio rerio) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF14396(CFTR_R) | 5 | PHE A1233ILE A1211ILE A1270VAL A1213LEU A1259 | None | 1.29A | 2ft9A-5w81A:undetectable | 2ft9A-5w81A:7.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydf | PARAFIBROMIN (Homo sapiens) |
no annotation | 5 | PHE A 27VAL A 25ASN A 66VAL A 86LEU A 8 | None | 1.09A | 2ft9A-5ydfA:undetectable | 2ft9A-5ydfA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yow | GLYCOPROTEINPOLYPROTEIN (Heartland virus) |
no annotation | 5 | PHE A 45VAL A 198ILE A 172VAL A 35LEU A 43 | None | 1.21A | 2ft9A-5yowA:undetectable | 2ft9A-5yowA:14.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9b | PLP-DEPENDENTL-ARGININEHYDROXYLASE MPPP (Streptomyceswadayamensis) |
no annotation | 5 | ILE A 216SER A 91VAL A 214PHE A 154LEU A 122 | NoneLLP A 221 ( 2.6A)NoneNoneNone | 1.24A | 2ft9A-6c9bA:undetectable | 2ft9A-6c9bA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fcx | METHYLENETETRAHYDROFOLATE REDUCTASE (Homo sapiens) |
no annotation | 5 | PHE A 207ILE A 225ILE A 252CYH A 250LEU A 211 | None | 1.28A | 2ft9A-6fcxA:undetectable | 2ft9A-6fcxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gy8 | - (-) |
no annotation | 5 | PHE A 359VAL A 378ILE A 133ILE A 130LEU A 174 | None | 1.16A | 2ft9A-6gy8A:undetectable | 2ft9A-6gy8A:undetectable |