SIMILAR PATTERNS OF AMINO ACIDS FOR 2F78_A_BEZA1003

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dcq PYK2-ASSOCIATED
PROTEIN BETA

(Mus musculus) 		PF01412
(ArfGap)
PF12796
(Ank_2) 		4 VAL A 513
SER A 312
ARG A 470
LEU A 469
 None
 1.00A 2f78A-1dcqA:
undetectable		 2f78A-1dcqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dhr DIHYDROPTERIDINE
REDUCTASE

(Rattus
norvegicus) 		PF00106
(adh_short) 		4 VAL A 176
LEU A  18
PHE A 203
THR A 199
 None
NAD  A 241 (-4.1A)
None
None
 1.13A 2f78A-1dhrA:
0.3		 2f78A-1dhrA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1epz DTDP-6-DEOXY-D-XYLO-
4-HEXULOSE
3,5-EPIMERASE

(Methanothermobacter
thermautotrophicus) 		PF00908
(dTDP_sugar_isom) 		4 VAL A 131
SER A  53
ARG A  61
HIS A  64
 None
None
TYD  A2187 (-3.7A)
TYD  A2187 (-4.3A)
 0.89A 2f78A-1epzA:
undetectable		 2f78A-1epzA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkk CHITOTRIOSIDASE-1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		4 VAL A 243
SER A 226
LEU A 347
PHE A 340
 None
 1.05A 2f78A-1hkkA:
0.0		 2f78A-1hkkA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2m REGULATOR OF
CHROMOSOME
CONDENSATION 1

(Homo sapiens) 		PF00415
(RCC1) 		4 VAL B 115
SER B  90
ARG B 101
THR B 103
 None
 1.12A 2f78A-1i2mB:
undetectable		 2f78A-1i2mB:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j89 HIGH AFFINITY
IMMUNOGLOBULIN
EPSILON RECEPTOR
ALPHA-SUBUNIT

(Homo sapiens) 		PF13895
(Ig_2)
PF13927
(Ig_3) 		4 VAL A   7
SER A  76
LEU A  53
PHE A  40
 None
 0.80A 2f78A-1j89A:
undetectable		 2f78A-1j89A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrf REGULATORY PROTEIN
BLAR1

(Bacillus
licheniformis) 		PF00905
(Transpeptidase) 		4 ARG A 534
LEU A 536
PHE A 565
THR A 560
 None
 0.95A 2f78A-1nrfA:
undetectable		 2f78A-1nrfA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE

(Saccharomyces
cerevisiae) 		PF00080
(Sod_Cu)
PF00403
(HMA) 		4 VAL A  48
SER A  50
LEU A  61
THR A  56
 None
 1.08A 2f78A-1qupA:
undetectable		 2f78A-1qupA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tt4 PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF04107
(GCS2) 		4 VAL A  22
SER A  31
HIS A  90
THR A  36
 None
 1.10A 2f78A-1tt4A:
undetectable		 2f78A-1tt4A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16

(Pachyrhizus
erosus) 		PF00407
(Bet_v_1) 		4 VAL A 131
LEU A  97
PHE A   3
THR A 121
 None
 1.08A 2f78A-1txcA:
undetectable		 2f78A-1txcA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ue0 ISOLEUCYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1) 		4 VAL A 238
LEU A 339
PHE A 324
THR A 342
 None
 1.08A 2f78A-1ue0A:
undetectable		 2f78A-1ue0A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upi DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE

(Mycobacterium
tuberculosis) 		PF00908
(dTDP_sugar_isom) 		4 VAL A 130
SER A  51
ARG A  59
HIS A  62
 None
 1.03A 2f78A-1upiA:
undetectable		 2f78A-1upiA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vf8 SECRETORY PROTEIN

(Mus musculus) 		PF00704
(Glyco_hydro_18) 		4 VAL A 222
SER A 205
LEU A 328
PHE A 321
 None
 1.11A 2f78A-1vf8A:
undetectable		 2f78A-1vf8A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpv UPF0230 PROTEIN
TM1468

(Thermotoga
maritima) 		PF02645
(DegV) 		4 SER A 122
LEU A 246
PHE A 162
THR A 276
 PLM  A 501 (-3.7A)
None
PLM  A 501 (-3.7A)
None
 0.97A 2f78A-1vpvA:
undetectable		 2f78A-1vpvA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w1k VANILLYL-ALCOHOL
OXIDASE

(Penicillium
simplicissimum) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		4 VAL A 394
ARG A 398
LEU A 280
THR A 310
 None
 1.13A 2f78A-1w1kA:
undetectable		 2f78A-1w1kA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		4 VAL A 366
SER A 370
LEU A 414
THR A 501
 None
 1.05A 2f78A-1w27A:
undetectable		 2f78A-1w27A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wb0 CHITOTRIOSIDASE 1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		4 VAL A 243
SER A 226
LEU A 349
PHE A 342
 None
 1.05A 2f78A-1wb0A:
undetectable		 2f78A-1wb0A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlt 176AA LONG
HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE

(Sulfurisphaera
tokodaii) 		PF00908
(dTDP_sugar_isom) 		4 VAL A 128
SER A  50
ARG A  58
HIS A  61
 None
 0.96A 2f78A-1wltA:
undetectable		 2f78A-1wltA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN

(Trichoplusia
ni;
Trichoplusia ni) 		PF00210
(Ferritin)
PF00210
(Ferritin) 		4 VAL M  88
LEU M  79
PHE A  62
THR A  67
 None
 1.04A 2f78A-1z6oM:
undetectable		 2f78A-1z6oM:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2auj DNA-DIRECTED RNA
POLYMERASE BETA'
CHAIN

(Thermus
aquaticus) 		no annotation 4 VAL D 347
ARG D 209
LEU D 387
PHE D 207
 None
 1.09A 2f78A-2aujD:
undetectable		 2f78A-2aujD:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9u HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE

(Sulfurisphaera
tokodaii) 		PF00908
(dTDP_sugar_isom) 		4 VAL A 128
SER A  50
ARG A  58
HIS A  61
 None
 0.96A 2f78A-2b9uA:
undetectable		 2f78A-2b9uA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dup VESICULAR
INTEGRAL-MEMBRANE
PROTEIN VIP36

(Canis lupus) 		PF03388
(Lectin_leg-like) 		4 VAL A 143
SER A 150
PHE A 154
THR A 138
 None
 0.93A 2f78A-2dupA:
undetectable		 2f78A-2dupA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5x BUGD

(Bordetella
pertussis) 		PF03401
(TctC) 		4 VAL A  40
LEU A  26
HIS A 227
THR A  19
 None
None
None
ASP  A 901 (-3.8A)
 1.15A 2f78A-2f5xA:
7.2		 2f78A-2f5xA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM

(Acinetobacter
baylyi) 		PF03466
(LysR_substrate) 		7 VAL A  97
SER A  99
ARG A 146
LEU A 147
PHE A 203
HIS A 206
THR A 267
 None
 0.63A 2f78A-2f6gA:
34.4		 2f78A-2f6gA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivf ETHYLBENZENE
DEHYDROGENASE
ALPHA-SUBUNIT
ETHYLBENZENE
DEHYDROGENASE
BETA-SUBUNIT

(Aromatoleum
aromaticum;
Aromatoleum
aromaticum) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF13247
(Fer4_11) 		4 ARG A 638
PHE B 103
HIS B  99
THR A 860
 MD1  A1987 (-3.7A)
None
None
None
 1.14A 2f78A-2ivfA:
undetectable		 2f78A-2ivfA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixc DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
RMLC

(Mycobacterium
tuberculosis) 		PF00908
(dTDP_sugar_isom) 		4 VAL A 130
SER A  51
ARG A  59
HIS A  62
 None
TRH  A1199 ( 4.8A)
TRH  A1199 (-4.0A)
TRH  A1199 (-3.5A)
 0.95A 2f78A-2ixcA:
undetectable		 2f78A-2ixcA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kk6 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FER

(Homo sapiens) 		PF00017
(SH2) 		4 VAL A 103
SER A 101
ARG A  62
HIS A  63
 None
 0.92A 2f78A-2kk6A:
undetectable		 2f78A-2kk6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l5p LIPOCALIN 12

(Rattus
norvegicus) 		PF00061
(Lipocalin) 		4 VAL A 143
SER A 158
LEU A 105
THR A  76
 None
 1.08A 2f78A-2l5pA:
undetectable		 2f78A-2l5pA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nbv UBIQUILIN-2

(Homo sapiens) 		PF00240
(ubiquitin) 		4 SER B  67
LEU B  74
PHE B  65
THR B  39
 None
 1.16A 2f78A-2nbvB:
undetectable		 2f78A-2nbvB:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pts ADENYLOSUCCINATE
LYASE

(Escherichia
coli) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		4 VAL A 234
SER A 230
LEU A 204
THR A 245
 None
 0.89A 2f78A-2ptsA:
undetectable		 2f78A-2ptsA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu8 GLUCOSE-6-PHOSPHATE
ISOMERASE

(Mycobacterium
tuberculosis) 		PF00342
(PGI) 		4 VAL A  46
LEU A  44
HIS A  58
THR A 470
 None
 1.07A 2f78A-2wu8A:
undetectable		 2f78A-2wu8A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xly CLOQ

(Streptomyces
roseochromogenus) 		PF11468
(PTase_Orf2) 		4 VAL A 216
LEU A 192
PHE A 186
HIS A 190
 None
 1.06A 2f78A-2xlyA:
undetectable		 2f78A-2xlyA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ybu ACIDIC MAMMALIAN
CHITINASE

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		4 VAL A 243
SER A 226
LEU A 349
PHE A 342
 None
 1.11A 2f78A-2ybuA:
undetectable		 2f78A-2ybuA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zau SELENIDE, WATER
DIKINASE

(Aquifex
aeolicus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 SER A  82
LEU A 299
HIS A 228
THR A 221
 None
 1.13A 2f78A-2zauA:
undetectable		 2f78A-2zauA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez6 PLASMID PARTITION
PROTEIN A

(Escherichia
coli) 		PF13614
(AAA_31) 		4 VAL A 359
SER A 128
LEU A 346
PHE A 384
 None
 1.00A 2f78A-3ez6A:
undetectable		 2f78A-3ez6A:
18.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM

(Acinetobacter
sp. ADP1) 		PF03466
(LysR_substrate) 		4 VAL A  97
SER A  99
ARG A 146
LEU A 147
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
CCU  A   3 (-4.4A)
 0.56A 2f78A-3glbA:
29.7		 2f78A-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM

(Acinetobacter
sp. ADP1) 		PF03466
(LysR_substrate) 		4 VAL A  97
SER A  99
ARG A 146
PHE A 203
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
None
 0.93A 2f78A-3glbA:
29.7		 2f78A-3glbA:
54.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzj POLYNEURIDINE-ALDEHY
DE ESTERASE

(Rauvolfia
serpentina) 		PF00561
(Abhydrolase_1) 		4 VAL A 106
SER A 105
LEU A 258
HIS A  38
 None
 1.04A 2f78A-3gzjA:
undetectable		 2f78A-3gzjA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ha2 NADPH-QUINONE
REDUCTASE

(Pediococcus
pentosaceus) 		PF02525
(Flavodoxin_2) 		4 SER A 100
LEU A  12
PHE A  21
THR A  17
 None
None
None
SO4  A 178 (-2.9A)
 1.07A 2f78A-3ha2A:
undetectable		 2f78A-3ha2A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Pseudomonas
syringae group
genomosp. 3) 		PF00106
(adh_short) 		4 VAL A 190
PHE A 150
HIS A  99
THR A 133
 None
 1.16A 2f78A-3i1jA:
undetectable		 2f78A-3i1jA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i8o KH DOMAIN-CONTAINING
PROTEIN MJ1533

(Methanocaldococcus
jannaschii) 		PF01850
(PIN) 		4 VAL A  35
SER A 135
ARG A  40
LEU A  44
 None
None
ACT  A 168 ( 4.1A)
None
 1.14A 2f78A-3i8oA:
2.1		 2f78A-3i8oA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbh MYOSIN 2 HEAVY CHAIN
STRIATED MUSCLE

(Aphonopelma) 		PF00063
(Myosin_head)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 VAL A 270
LEU A 265
PHE A 227
THR A 432
 None
 1.11A 2f78A-3jbhA:
undetectable		 2f78A-3jbhA:
7.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM

(Acinetobacter
sp. ADP1) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		6 VAL A  97
SER A  99
ARG A 146
LEU A 147
HIS A 206
THR A 267
 None
 0.75A 2f78A-3k1nA:
32.3		 2f78A-3k1nA:
74.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k1n HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM

(Acinetobacter
sp. ADP1) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		6 VAL A  97
SER A  99
LEU A 147
PHE A 203
HIS A 206
THR A 267
 None
 0.72A 2f78A-3k1nA:
32.3		 2f78A-3k1nA:
74.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3las PUTATIVE CARBONIC
ANHYDRASE

(Streptococcus
mutans) 		PF00484
(Pro_CA) 		4 VAL A 131
SER A 130
LEU A  89
HIS A  91
 None
None
None
ZN  A 167 (-3.2A)
 0.94A 2f78A-3lasA:
undetectable		 2f78A-3lasA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mq3 PYRUVATE
DEHYDROGENASE
PHOSPHATASE 1

(Bos taurus) 		PF00481
(PP2C) 		4 SER A  36
LEU A  69
HIS A 122
THR A  60
 None
 1.07A 2f78A-3mq3A:
undetectable		 2f78A-3mq3A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mws HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 VAL A  13
LEU A  24
PHE A  89
THR A  31
 None
 1.09A 2f78A-3mwsA:
undetectable		 2f78A-3mwsA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqx SECRETED
METALLOPROTEASE
MCP02

(Pseudoalteromonas
sp. SM9913) 		PF01447
(Peptidase_M4)
PF02868
(Peptidase_M4_C) 		4 VAL A 338
SER A 343
LEU A 278
HIS A 282
 None
 1.07A 2f78A-3nqxA:
undetectable		 2f78A-3nqxA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nra ASPARTATE
AMINOTRANSFERASE

(Rhodobacter
sphaeroides) 		PF00155
(Aminotran_1_2) 		4 VAL A 244
ARG A 234
HIS A 232
THR A  94
 None
 1.10A 2f78A-3nraA:
0.8		 2f78A-3nraA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT
6-PHOSPHOFRUCTO-1-KI
NASE BETA-SUBUNIT

(Komagataella
pastoris;
Komagataella
pastoris) 		PF00365
(PFK)
PF00365
(PFK) 		4 SER A 472
ARG A 490
LEU A 491
THR B 463
 SO4  A1000 (-2.8A)
SO4  A1000 (-3.9A)
None
None
 1.06A 2f78A-3opyA:
undetectable		 2f78A-3opyA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3l CYTOCHROME P450

(Streptomyces
thioluteus) 		PF00067
(p450) 		4 SER A 345
ARG A 362
LEU A 365
THR A 358
 None
 1.13A 2f78A-3p3lA:
undetectable		 2f78A-3p3lA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qha PUTATIVE
OXIDOREDUCTASE

(Mycobacterium
avium) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 SER A 128
ARG A 180
LEU A 178
THR A 184
 None
 1.15A 2f78A-3qhaA:
undetectable		 2f78A-3qhaA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qki GLUCOSE-6-PHOSPHATE
ISOMERASE

(Plasmodium
falciparum) 		PF00342
(PGI) 		4 SER A 513
ARG A  99
PHE A 318
THR A 298
 None
 1.15A 2f78A-3qkiA:
undetectable		 2f78A-3qkiA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rfr PMOA

(Methylocystis
sp. M) 		no annotation 4 VAL J  57
SER J 122
PHE J 193
HIS J 192
 None
 1.06A 2f78A-3rfrJ:
undetectable		 2f78A-3rfrJ:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqp ENOLASE

(Coxiella
burnetii) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 VAL A 196
SER A 202
PHE A 188
HIS A 189
 None
 1.12A 2f78A-3tqpA:
undetectable		 2f78A-3tqpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0o SELENIDE, WATER
DIKINASE

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 SER A  90
LEU A 306
HIS A 236
THR A 229
 None
None
None
MG  A 401 ( 4.1A)
 1.10A 2f78A-3u0oA:
undetectable		 2f78A-3u0oA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u3g RIBONUCLEASE H

(uncultured
organism) 		no annotation 4 VAL D  23
SER D  36
ARG D  55
LEU D  57
 None
 1.09A 2f78A-3u3gD:
undetectable		 2f78A-3u3gD:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1

(Rattus
norvegicus) 		no annotation 4 SER A 141
ARG A  71
LEU A  85
HIS A 124
 None
 1.14A 2f78A-3u9gA:
undetectable		 2f78A-3u9gA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vas PUTATIVE ADENOSINE
KINASE

(Schistosoma
mansoni) 		PF00294
(PfkB) 		4 VAL A 209
SER A 202
LEU A 250
THR A 243
 None
 1.11A 2f78A-3vasA:
undetectable		 2f78A-3vasA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbk EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5B

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		4 VAL A 567
SER A 571
LEU A 591
PHE A 464
 None
 1.06A 2f78A-3wbkA:
undetectable		 2f78A-3wbkA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdf GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Thermosynechococcus
elongatus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 SER A 293
ARG A 324
LEU A 328
HIS A 139
 None
 1.10A 2f78A-3zdfA:
undetectable		 2f78A-3zdfA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg2 PATF

(Prochloron
didemni) 		no annotation 4 VAL A  51
SER A  53
LEU A  17
THR A  22
 None
 1.16A 2f78A-4bg2A:
undetectable		 2f78A-4bg2A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Bacillus
anthracis) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL A  92
LEU A 118
PHE A  99
THR A  96
 None
 1.03A 2f78A-4dibA:
undetectable		 2f78A-4dibA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e14 KYNURENINE
FORMAMIDASE

(Drosophila
melanogaster) 		PF07859
(Abhydrolase_3) 		4 VAL A 114
LEU A  47
HIS A  43
THR A  40
 None
 1.16A 2f78A-4e14A:
undetectable		 2f78A-4e14A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 VAL A 875
SER A 874
LEU A 860
THR A 831
 None
 0.96A 2f78A-4ecnA:
undetectable		 2f78A-4ecnA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gnx PUTATIVE
UNCHARACTERIZED
PROTEIN
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Ustilago
maydis;
Ustilago maydis) 		PF08661
(Rep_fac-A_3)
PF01336
(tRNA_anti-codon) 		4 VAL A  99
SER A 103
ARG B 163
HIS B 162
 None
 1.11A 2f78A-4gnxA:
undetectable		 2f78A-4gnxA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4im8 ADVANCED GLYCATION
END-PRODUCTS
RECEPTOR

(Mus musculus) 		PF00047
(ig)
PF08205
(C2-set_2) 		4 VAL A 172
SER A 189
LEU A 163
HIS A 157
 None
 0.99A 2f78A-4im8A:
undetectable		 2f78A-4im8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j75 TRYPTOPHANYL-TRNA
SYNTHETASE

(Plasmodium
falciparum) 		PF00579
(tRNA-synt_1b) 		4 VAL A 600
LEU A 321
PHE A 518
HIS A 317
 None
 1.16A 2f78A-4j75A:
undetectable		 2f78A-4j75A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l62 TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N)
PF16925
(TetR_C_13) 		4 VAL A 114
SER A 118
LEU A 106
THR A 124
 None
 1.08A 2f78A-4l62A:
undetectable		 2f78A-4l62A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lis UDP-GLUCOSE
4-EPIMERASE

(Aspergillus
nidulans) 		PF16363
(GDP_Man_Dehyd) 		4 VAL A 170
PHE A 125
HIS A  83
THR A 108
 IOD  A 406 ( 4.9A)
None
None
None
 1.10A 2f78A-4lisA:
undetectable		 2f78A-4lisA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5p NADPH DEHYDROGENASE

(Scheffersomyces
stipitis) 		PF00724
(Oxidored_FMN) 		4 VAL A 101
LEU A  63
PHE A 182
THR A  66
 None
 1.05A 2f78A-4m5pA:
undetectable		 2f78A-4m5pA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 VAL D 489
LEU D 352
PHE D 484
THR D 345
 MLY  D 488 ( 3.3A)
None
MLY  D 488 ( 4.8A)
None
 1.07A 2f78A-4ngeD:
undetectable		 2f78A-4ngeD:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p98 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN

(Conexibacter
woesei) 		PF02608
(Bmp) 		4 VAL A  95
SER A 118
LEU A  60
THR A 266
 None
 1.05A 2f78A-4p98A:
2.9		 2f78A-4p98A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppr PENICILLIN-BINDING
PROTEIN DACB1

(Mycobacterium
tuberculosis) 		PF00768
(Peptidase_S11) 		4 VAL A 294
LEU A  98
PHE A 233
THR A 225
 None
 0.91A 2f78A-4pprA:
undetectable		 2f78A-4pprA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4sbv SOUTHERN BEAN MOSAIC
VIRUS COAT PROTEIN

(Southern bean
mosaic virus) 		PF00729
(Viral_coat) 		4 SER A 245
LEU A 120
PHE A 170
THR A 184
 None
 1.10A 2f78A-4sbvA:
undetectable		 2f78A-4sbvA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4um8 INTEGRIN ALPHA-V

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 VAL A 226
SER A 241
LEU A 171
THR A 210
 None
 1.02A 2f78A-4um8A:
undetectable		 2f78A-4um8A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2

(Saccharomyces
cerevisiae) 		PF00881
(Nitroreductase) 		4 VAL A  52
SER A  50
LEU A 100
PHE A 117
 None
 1.15A 2f78A-4urpA:
undetectable		 2f78A-4urpA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xz3 ACYL-COA SYNTHETASE
(NDP FORMING)

(Candidatus
Korarchaeum
cryptofilum) 		PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig) 		4 VAL A 182
SER A 180
LEU A 190
PHE A 198
 None
 1.11A 2f78A-4xz3A:
1.8		 2f78A-4xz3A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		4 VAL A  37
SER A  74
LEU A 102
THR A  89
 None
 1.15A 2f78A-4ybrA:
undetectable		 2f78A-4ybrA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxl O-GLCNACASE NAGJ

(Clostridium
perfringens) 		PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase) 		4 VAL A 171
SER A 137
LEU A  46
PHE A 159
 None
 1.08A 2f78A-4zxlA:
undetectable		 2f78A-4zxlA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b37 TRYPTOPHAN
DEHYDROGENASE

(Nostoc
punctiforme) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 VAL A 282
LEU A 335
PHE A 318
THR A 328
 None
 1.08A 2f78A-5b37A:
undetectable		 2f78A-5b37A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cm9 RAL GUANINE
NUCLEOTIDE
DISSOCIATION
STIMULATOR-LIKE 2

(Mus musculus) 		PF00617
(RasGEF)
PF00618
(RasGEF_N) 		4 VAL A 162
LEU A 120
HIS A 103
THR A 109
 None
 0.91A 2f78A-5cm9A:
undetectable		 2f78A-5cm9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dl6 PUTATIVE PORIN FOR
VANILLATE
TRAFFICKING (VANP)

(Acinetobacter
baumannii) 		PF03573
(OprD) 		4 SER A 305
LEU A 287
PHE A 296
THR A 291
 None
 1.07A 2f78A-5dl6A:
undetectable		 2f78A-5dl6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dlk TQAA

(Penicillium
aethiopicum) 		PF00668
(Condensation) 		4 ARG A 335
LEU A 334
HIS A 353
THR A 337
 None
 1.04A 2f78A-5dlkA:
undetectable		 2f78A-5dlkA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 SER A 100
LEU A 112
HIS A 110
THR A 136
 None
 1.12A 2f78A-5ereA:
4.4		 2f78A-5ereA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f17 NON-STRUCTURAL
PROTEIN 11

(Equine
arteritis virus) 		no annotation 4 VAL A  74
SER A 102
ARG A 104
PHE A 105
 None
 0.82A 2f78A-5f17A:
undetectable		 2f78A-5f17A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ

(Bacillus
amyloliquefaciens) 		PF12704
(MacB_PCD) 		4 SER A 177
LEU A  79
PHE A 164
THR A 173
 None
 1.10A 2f78A-5f9qA:
undetectable		 2f78A-5f9qA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gha SULFUR TRANSFERASE
TTUA

(Thermus
thermophilus) 		PF01171
(ATP_bind_3) 		4 VAL A  12
SER A 208
LEU A  19
PHE A  30
 None
 1.01A 2f78A-5ghaA:
undetectable		 2f78A-5ghaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ie2 OXALATE--COA LIGASE

(Arabidopsis
thaliana) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 VAL A 232
SER A 225
HIS A 216
THR A 258
 None
None
ACY  A 603 (-4.5A)
None
 1.10A 2f78A-5ie2A:
undetectable		 2f78A-5ie2A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE

(Porphyromonas
endodontalis) 		PF10459
(Peptidase_S46) 		4 VAL A 122
LEU A  73
PHE A 230
THR A  82
 None
 1.14A 2f78A-5jxkA:
undetectable		 2f78A-5jxkA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k82 APOLIPOPROTEIN B
MRNA EDITING ENZYME,
CATALYTIC
PEPTIDE-LIKE
3G,APOLIPOPROTEIN B
MRNA EDITING ENZYME,
CATALYTIC
PEPTIDE-LIKE 3G

(Macaca mulatta) 		PF08210
(APOBEC_N) 		4 VAL A 120
LEU A 135
PHE A 126
THR A 188
 None
 1.08A 2f78A-5k82A:
undetectable		 2f78A-5k82A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mgy FAD:PROTEIN FMN
TRANSFERASE

(Pseudomonas
stutzeri) 		no annotation 4 VAL H 286
SER H 253
LEU H 306
THR H 270
 None
 1.04A 2f78A-5mgyH:
undetectable		 2f78A-5mgyH:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 4 VAL A 631
ARG A 728
LEU A 253
THR A 730
 None
 1.06A 2f78A-5nd1A:
undetectable		 2f78A-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn8 LYSOSOMAL
ALPHA-GLUCOSIDASE

(Homo sapiens) 		no annotation 4 VAL A 740
LEU A 745
PHE A 767
THR A 753
 EDO  A1023 (-3.6A)
None
None
None
 1.14A 2f78A-5nn8A:
undetectable		 2f78A-5nn8A:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sy4 CHAPERONE YAJL

(Escherichia
coli) 		PF01965
(DJ-1_PfpI) 		4 VAL A 144
SER A 155
LEU A 166
THR A  21
 None
 1.10A 2f78A-5sy4A:
2.0		 2f78A-5sy4A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vrv PROTEIN REGULATED BY
ACID PH

(Agrobacterium
fabrum) 		PF09924
(DUF2156) 		4 SER A 720
ARG A 561
LEU A 559
THR A 546
 None
 1.15A 2f78A-5vrvA:
undetectable		 2f78A-5vrvA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wso NS3 HELICASE

(Pestivirus A) 		no annotation 4 VAL A 313
SER A 343
ARG A 309
LEU A 308
 None
 1.15A 2f78A-5wsoA:
undetectable		 2f78A-5wsoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xau LAMININ SUBUNIT
ALPHA-5

(Homo sapiens) 		PF02210
(Laminin_G_2)
PF06009
(Laminin_II) 		4 VAL A3267
SER A3149
LEU A3135
PHE A3151
 None
 0.95A 2f78A-5xauA:
undetectable		 2f78A-5xauA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0n CLC-TYPE
FLUORIDE/PROTON
ANTIPORTER

(Enterococcus
casseliflavus) 		no annotation 4 SER A  21
LEU A 169
HIS A 180
THR A 144
 None
None
DMU  A 501 ( 4.6A)
DMU  A 501 (-3.9A)
 1.14A 2f78A-6d0nA:
undetectable		 2f78A-6d0nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5o POLYMERASE ACIDIC
PROTEIN

(Influenza B
virus) 		no annotation 4 VAL A 344
SER A 348
ARG A 317
LEU A 316
 None
 1.13A 2f78A-6f5oA:
undetectable		 2f78A-6f5oA:
undetectable