SIMILAR PATTERNS OF AMINO ACIDS FOR 2EJT_A_SAMA501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1am2 MXE GYRA INTEIN

(Mycobacterium
xenopi) 		no annotation 3 ARG A 160
ASP A 154
ASP A 148
 None
 0.81A 2ejtA-1am2A:
undetectable		 2ejtA-1am2A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1avm SUPEROXIDE DISMUTASE

(Propionibacterium
freudenreichii) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		3 ARG A 199
ASP A 101
ASP A 108
 None
 0.87A 2ejtA-1avmA:
undetectable		 2ejtA-1avmA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bbu PROTEIN (LYSYL-TRNA
SYNTHETASE)

(Escherichia
coli) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		3 ARG A 262
ASP A 450
ASP A 447
 LYS  A 505 (-4.0A)
None
None
 0.86A 2ejtA-1bbuA:
undetectable		 2ejtA-1bbuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cb8 PROTEIN
(CHONDROITINASE AC)

(Pedobacter
heparinus) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		3 ARG A 381
ASP A 452
ASP A 434
 None
 0.78A 2ejtA-1cb8A:
undetectable		 2ejtA-1cb8A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN 2

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16) 		3 ARG B  53
ASP B  83
ASP B 277
 None
 0.80A 2ejtA-1ezvB:
undetectable		 2ejtA-1ezvB:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1izo CYTOCHROME P450
152A1

(Bacillus
subtilis) 		PF00067
(p450) 		3 ARG A 144
ASP A 164
ASP A 171
 None
 0.75A 2ejtA-1izoA:
undetectable		 2ejtA-1izoA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p49 STERYL-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase)
PF14707
(Sulfatase_C) 		3 ARG A  51
ASP A  41
ASP A  36
 None
NAG  A 603 (-4.1A)
CA  A 605 (-2.5A)
 0.90A 2ejtA-1p49A:
undetectable		 2ejtA-1p49A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ph5 TELOMERE-BINDING
PROTEIN ALPHA
SUBUNIT

(Sterkiella nova) 		PF02765
(POT1) 		3 ARG A 274
ASP A 209
ASP A  93
 None
 0.71A 2ejtA-1ph5A:
undetectable		 2ejtA-1ph5A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pl0 BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH

(Homo sapiens) 		PF01808
(AICARFT_IMPCHas)
PF02142
(MGS) 		3 ARG A 335
ASP A 326
ASP A 323
 None
 0.86A 2ejtA-1pl0A:
2.7		 2ejtA-1pl0A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rxw FLAP
STRUCTURE-SPECIFIC
ENDONUCLEASE

(Archaeoglobus
fulgidus) 		PF00752
(XPG_N)
PF00867
(XPG_I) 		3 ARG A 289
ASP A 147
ASP A  80
 None
 0.81A 2ejtA-1rxwA:
undetectable		 2ejtA-1rxwA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfj CONSERVED
HYPOTHETICAL PROTEIN

(Caulobacter
vibrioides) 		PF02578
(Cu-oxidase_4) 		3 ARG A 252
ASP A  96
ASP A 139
 None
 0.72A 2ejtA-1xfjA:
undetectable		 2ejtA-1xfjA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xu0 PRION PROTEIN

(Xenopus laevis) 		PF00377
(Prion) 		3 ARG A 167
ASP A 180
ASP A 175
 None
 0.82A 2ejtA-1xu0A:
undetectable		 2ejtA-1xu0A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ycn PUTATIVE
CA2+-DEPENDENT
MEMBRANE-BINDING
PROTEIN ANNEXIN

(Arabidopsis
thaliana) 		PF00191
(Annexin) 		3 ARG A 196
ASP A 186
ASP A 181
 None
 0.62A 2ejtA-1ycnA:
undetectable		 2ejtA-1ycnA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bbk METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans) 		PF06433
(Me-amine-dh_H) 		3 ARG H  33
ASP H  75
ASP H 134
 None
 0.74A 2ejtA-2bbkH:
undetectable		 2ejtA-2bbkH:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2

(Carnivore
protoparvovirus
1) 		PF00740
(Parvo_coat) 		3 ARG A 209
ASP A 100
ASP A  88
 None
 0.78A 2ejtA-2casA:
undetectable		 2ejtA-2casA:
21.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dul N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF02005
(TRM) 		3 ARG A  36
ASP A  78
ASP A 120
 None
 0.23A 2ejtA-2dulA:
62.9		 2ejtA-2dulA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eax PEPTIDOGLYCAN
RECOGNITION
PROTEIN-I-BETA

(Homo sapiens) 		PF01510
(Amidase_2) 		3 ARG A 253
ASP A 258
ASP A 265
 None
 0.89A 2ejtA-2eaxA:
undetectable		 2ejtA-2eaxA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exr CYTOKININ
DEHYDROGENASE 7

(Arabidopsis
thaliana) 		PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind) 		3 ARG A 349
ASP A 258
ASP A 253
 None
 0.79A 2ejtA-2exrA:
undetectable		 2ejtA-2exrA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h09 TRANSCRIPTIONAL
REGULATOR MNTR

(Escherichia
coli) 		PF01325
(Fe_dep_repress)
PF02742
(Fe_dep_repr_C) 		3 ARG A  35
ASP A  40
ASP A  47
 None
 0.89A 2ejtA-2h09A:
undetectable		 2ejtA-2h09A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ice COMPLEMENT C3 BETA
CHAIN

(Homo sapiens) 		PF01835
(A2M_N)
PF07703
(A2M_N_2) 		3 ARG A 456
ASP A 527
ASP A 619
 None
 0.85A 2ejtA-2iceA:
undetectable		 2ejtA-2iceA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k2c RING FINGER AND CHY
ZINC FINGER
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF05495
(zf-CHY) 		3 ARG A  54
ASP A  45
ASP A  49
 None
 0.89A 2ejtA-2k2cA:
undetectable		 2ejtA-2k2cA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l8k NON-STRUCTURAL
PROTEIN 7

(Equine
arteritis virus) 		PF16749
(Arteri_nsp7a) 		3 ARG A  60
ASP A  19
ASP A  81
 None
 0.54A 2ejtA-2l8kA:
undetectable		 2ejtA-2l8kA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6

(Homo sapiens) 		PF01852
(START) 		3 ARG A 109
ASP A  75
ASP A  70
 None
 0.84A 2ejtA-2mouA:
undetectable		 2ejtA-2mouA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nzt HEXOKINASE-2

(Homo sapiens) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		3 ARG A  69
ASP A 164
ASP A 202
 None
 0.74A 2ejtA-2nztA:
undetectable		 2ejtA-2nztA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2k METHIONINE SYNTHASE

(Homo sapiens) 		PF02965
(Met_synt_B12) 		3 ARG A1027
ASP A 965
ASP A 971
 None
 0.82A 2ejtA-2o2kA:
undetectable		 2ejtA-2o2kA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o61 TRANSCRIPTION FACTOR
P65/INTERFERON
REGULATORY FACTOR
7/INTERFERON
REGULATORY FACTOR 3
FUSION PROTEIN

(Homo sapiens) 		PF00554
(RHD_DNA_bind)
PF00605
(IRF)
PF16179
(RHD_dimer) 		3 ARG A2081
ASP A2072
ASP A2069
 None
 0.78A 2ejtA-2o61A:
undetectable		 2ejtA-2o61A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ob1 LEUCINE CARBOXYL
METHYLTRANSFERASE 1

(Saccharomyces
cerevisiae) 		PF04072
(LCM) 		3 ARG A 111
ASP A 128
ASP A 175
 PO4  A2001 (-3.4A)
None
None
 0.73A 2ejtA-2ob1A:
9.1		 2ejtA-2ob1A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsj P-COUMARIC ACID
DECARBOXYLASE

(Lactobacillus
plantarum) 		PF05870
(PA_decarbox) 		3 ARG A  48
ASP A  37
ASP A 149
 IPA  A1180 ( 3.8A)
NA  A1181 ( 3.7A)
None
 0.80A 2ejtA-2wsjA:
undetectable		 2ejtA-2wsjA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xu0 ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding)
PF15447
(NTS) 		3 ARG A 480
ASP A 340
ASP A 369
 None
 0.89A 2ejtA-2xu0A:
undetectable		 2ejtA-2xu0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyb HYPOTHETICAL PROTEIN
TTHA1606

(Thermus
thermophilus) 		PF01784
(NIF3) 		3 ARG A 144
ASP A 183
ASP A 181
 None
 0.80A 2ejtA-2yybA:
undetectable		 2ejtA-2yybA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0u WW DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00168
(C2) 		3 ARG A  79
ASP A  82
ASP A  56
 None
 0.81A 2ejtA-2z0uA:
undetectable		 2ejtA-2z0uA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu MUS81 PROTEIN

(Danio rerio) 		PF02732
(ERCC4) 		3 ARG A 414
ASP A 326
ASP A 353
 None
 0.80A 2ejtA-2ziuA:
undetectable		 2ejtA-2ziuA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ay0 UNCHARACTERIZED
PROTEIN MJ0883

(Methanocaldococcus
jannaschii) 		PF02475
(Met_10) 		3 ARG A 186
ASP A 223
ASP A 251
 None
ADN  A 401 (-2.6A)
ADN  A 401 (-3.8A)
 0.63A 2ejtA-3ay0A:
17.6		 2ejtA-3ay0A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdk D-MANNONATE
DEHYDRATASE

(Streptococcus
suis) 		PF03786
(UxuA) 		3 ARG A 242
ASP A 221
ASP A 130
 None
None
DNO  A 387 (-3.4A)
 0.73A 2ejtA-3bdkA:
0.8		 2ejtA-3bdkA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cma 50S RIBOSOMAL
PROTEIN L32E

(Haloarcula
marismortui) 		PF01655
(Ribosomal_L32e) 		3 ARG Y 175
ASP Y 113
ASP Y 108
 G  01269 ( 3.4A)
None
None
 0.82A 2ejtA-3cmaY:
undetectable		 2ejtA-3cmaY:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ggd SAM-DEPENDENT
METHYLTRANSFERASE

(Trichormus
variabilis) 		PF13649
(Methyltransf_25) 		3 ARG A 130
ASP A  84
ASP A 108
 SAH  A 248 ( 3.9A)
SAH  A 248 (-2.9A)
SAH  A 248 (-3.7A)
 0.52A 2ejtA-3ggdA:
9.6		 2ejtA-3ggdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h68 SERINE/THREONINE-PRO
TEIN PHOSPHATASE 5

(Homo sapiens) 		PF00149
(Metallophos)
PF08321
(PPP5) 		3 ARG A 373
ASP A 383
ASP A 388
 None
 0.66A 2ejtA-3h68A:
undetectable		 2ejtA-3h68A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h6z POLYCOMB PROTEIN
SFMBT

(Drosophila
melanogaster) 		PF02820
(MBT) 		3 ARG A 922
ASP A 725
ASP A 723
 None
 0.87A 2ejtA-3h6zA:
undetectable		 2ejtA-3h6zA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6x SOLUTE-BINDING
PROTEIN MA_0280

(Methanosarcina
acetivorans) 		PF13531
(SBP_bac_11) 		3 ARG A 148
ASP A 186
ASP A 181
 None
 0.81A 2ejtA-3k6xA:
undetectable		 2ejtA-3k6xA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE

(Corynebacterium
glutamicum) 		PF13409
(GST_N_2)
PF13410
(GST_C_2) 		3 ARG A 264
ASP A 253
ASP A 317
 None
 0.84A 2ejtA-3m1gA:
undetectable		 2ejtA-3m1gA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nhe UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2

(Homo sapiens) 		PF00443
(UCH) 		3 ARG A 493
ASP A 408
ASP A 303
 None
 0.78A 2ejtA-3nheA:
undetectable		 2ejtA-3nheA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3niz RHODANESE FAMILY
PROTEIN

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		3 ARG A 143
ASP A 162
ASP A 104
 None
MG  A 312 ( 3.3A)
ADP  A 314 (-4.1A)
 0.81A 2ejtA-3nizA:
undetectable		 2ejtA-3nizA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8s ADP-RIBOSE
PYROPHOSPHATASE

(Streptococcus
suis) 		PF00293
(NUDIX) 		3 ARG A 125
ASP A  80
ASP A 173
 ACT  A 211 (-3.4A)
None
None
 0.85A 2ejtA-3o8sA:
undetectable		 2ejtA-3o8sA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ow2 50S RIBOSOMAL
PROTEIN L32E

(Haloarcula
marismortui) 		PF01655
(Ribosomal_L32e) 		3 ARG X 175
ASP X 113
ASP X 108
 G  01269 ( 3.6A)
None
None
 0.78A 2ejtA-3ow2X:
undetectable		 2ejtA-3ow2X:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r31 BETAINE ALDEHYDE
DEHYDROGENASE

(Agrobacterium
fabrum) 		PF00171
(Aldedh) 		3 ARG A  88
ASP A 113
ASP A 101
 None
 0.90A 2ejtA-3r31A:
4.8		 2ejtA-3r31A:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8v RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L

(Escherichia
coli) 		PF01170
(UPF0020)
PF02926
(THUMP)
PF10672
(Methyltrans_SAM) 		3 ARG A 530
ASP A 568
ASP A 597
 None
SAM  A 802 (-2.9A)
SAM  A 802 (-3.5A)
 0.62A 2ejtA-3v8vA:
14.2		 2ejtA-3v8vA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vse PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF10672
(Methyltrans_SAM) 		3 ARG A 205
ASP A 243
ASP A 272
 None
SAH  A 401 (-2.7A)
SAH  A 401 (-3.0A)
 0.72A 2ejtA-3vseA:
14.3		 2ejtA-3vseA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vwa CYTOPLASMIC EXPORT
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 3 ARG A 230
ASP A 191
ASP A 186
 None
 0.80A 2ejtA-3vwaA:
undetectable		 2ejtA-3vwaA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wy2 ALPHA-GLUCOSIDASE

(Halomonas sp.
H11) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		3 ARG A 181
ASP A 186
ASP A 193
 GOL  A 602 (-4.3A)
None
None
 0.82A 2ejtA-3wy2A:
undetectable		 2ejtA-3wy2A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zkb DNA GYRASE SUBUNIT B

(Mycobacterium
tuberculosis) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		3 ARG A 172
ASP A  79
ASP A  55
 None
ANP  A 601 (-3.7A)
None
 0.89A 2ejtA-3zkbA:
undetectable		 2ejtA-3zkbA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akr F-ACTIN-CAPPING
PROTEIN SUBUNIT BETA

(Dictyostelium
discoideum) 		PF01115
(F_actin_cap_B) 		3 ARG B  14
ASP B  44
ASP B  63
 None
 0.81A 2ejtA-4akrB:
undetectable		 2ejtA-4akrB:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awn DEOXYRIBONUCLEASE-1

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		3 ARG A 117
ASP A 153
ASP A  99
 None
None
CA  A 300 (-2.5A)
 0.55A 2ejtA-4awnA:
undetectable		 2ejtA-4awnA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 2
GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 5

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF04153
(NOT2_3_5)
PF04153
(NOT2_3_5) 		3 ARG C 533
ASP C 473
ASP B 109
 None
 0.73A 2ejtA-4by6C:
undetectable		 2ejtA-4by6C:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Burkholderia
thailandensis) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		3 ARG A 161
ASP A 146
ASP A 110
 None
 0.84A 2ejtA-4eqyA:
undetectable		 2ejtA-4eqyA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ex5 LYSINE--TRNA LIGASE

(Burkholderia
thailandensis) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		3 ARG A 262
ASP A 454
ASP A 451
 LYS  A 601 (-3.7A)
None
None
 0.84A 2ejtA-4ex5A:
undetectable		 2ejtA-4ex5A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f1k THROMBOSPONDIN
RELATED ANONYMOUS
PROTEIN

(Plasmodium
falciparum) 		PF00092
(VWA) 		3 ARG A 181
ASP A  48
ASP A  45
 SO4  A 303 (-4.2A)
None
None
 0.75A 2ejtA-4f1kA:
undetectable		 2ejtA-4f1kA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f8q BUTYROPHILIN
SUBFAMILY 3 MEMBER
A2

(Homo sapiens) 		PF07686
(V-set) 		3 ARG A  72
ASP A 101
ASP A 103
 None
 0.68A 2ejtA-4f8qA:
undetectable		 2ejtA-4f8qA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fe2 PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Streptococcus
pneumoniae) 		PF01259
(SAICAR_synt) 		3 ARG A 214
ASP A 128
ASP A 125
 AIR  A 301 (-3.1A)
ASP  A 306 ( 4.0A)
None
 0.79A 2ejtA-4fe2A:
undetectable		 2ejtA-4fe2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gf8 PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Vibrio cholerae) 		PF00496
(SBP_bac_5) 		3 ARG A 120
ASP A  60
ASP A 458
 None
 0.82A 2ejtA-4gf8A:
undetectable		 2ejtA-4gf8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4haq GH7 FAMILY PROTEIN

(Limnoria
quadripunctata) 		PF00840
(Glyco_hydro_7) 		3 ARG A 128
ASP A 394
ASP A 426
 None
 0.87A 2ejtA-4haqA:
undetectable		 2ejtA-4haqA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoz SUCROSE ISOMERASE

(Erwinia
rhapontici) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ARG A 328
ASP A 322
ASP A 302
 None
 0.87A 2ejtA-4hozA:
undetectable		 2ejtA-4hozA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkw BUTYROPHILIN
SUBFAMILY 3 MEMBER
A1

(Homo sapiens) 		PF07686
(V-set) 		3 ARG A  74
ASP A 103
ASP A 105
 None
 0.67A 2ejtA-4jkwA:
undetectable		 2ejtA-4jkwA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksf MALONYL-COA
DECARBOXYLASE

(Agrobacterium
vitis) 		PF05292
(MCD)
PF17408
(MCD_N) 		3 ARG A 397
ASP A 244
ASP A 251
 None
 0.54A 2ejtA-4ksfA:
undetectable		 2ejtA-4ksfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kyi VIPD

(Legionella
pneumophila) 		PF01734
(Patatin) 		3 ARG A 112
ASP A 116
ASP A 123
 None
 0.77A 2ejtA-4kyiA:
undetectable		 2ejtA-4kyiA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mk0 BETA-ADRENERGIC
RECEPTOR KINASE 1

(Homo sapiens) 		PF00069
(Pkinase)
PF00169
(PH)
PF00615
(RGS) 		3 ARG A 316
ASP A 335
ASP A 278
 None
29X  A 702 (-4.4A)
29X  A 702 ( 4.8A)
 0.79A 2ejtA-4mk0A:
undetectable		 2ejtA-4mk0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n01 PERIPLASMIC BINDING
PROTEIN

(Veillonella
parvula) 		PF01497
(Peripla_BP_2) 		3 ARG A 305
ASP A 212
ASP A 215
 None
GOL  A 404 ( 4.5A)
None
 0.67A 2ejtA-4n01A:
3.1		 2ejtA-4n01A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxg TYPE-2 RESTRICTION
ENZYME SAU3AI

(Staphylococcus
aureus) 		PF02976
(MutH) 		3 ARG A 199
ASP A 150
ASP A 143
 None
 0.82A 2ejtA-4pxgA:
undetectable		 2ejtA-4pxgA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qyr AT-LESS POLYKETIDE
SYNTHASE

(Streptomyces
platensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 ARG A2570
ASP A3020
ASP A3015
 None
 0.68A 2ejtA-4qyrA:
undetectable		 2ejtA-4qyrA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2

(Erythrobacter
litoralis) 		PF07568
(HisKA_2)
PF13426
(PAS_9)
PF13581
(HATPase_c_2) 		3 ARG A  15
ASP A 187
ASP A 134
 None
 0.76A 2ejtA-4r3aA:
undetectable		 2ejtA-4r3aA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rml LATROPHILIN-3

(Mus musculus) 		PF02191
(OLF) 		3 ARG A 246
ASP A 275
ASP A 332
 None
TRS  A 602 (-2.7A)
MG  A 601 ( 4.6A)
 0.72A 2ejtA-4rmlA:
undetectable		 2ejtA-4rmlA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ubd MONOCLONAL ANTIBODY
H CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ARG C 104
ASP C  99
ASP C  59
 None
 0.85A 2ejtA-4ubdC:
undetectable		 2ejtA-4ubdC:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4us5 LUCIFERASE-LIKE
MONOOXYGENASE

(Streptomyces
bottropensis) 		PF00296
(Bac_luciferase) 		3 ARG A 323
ASP A 314
ASP A 258
 None
 0.84A 2ejtA-4us5A:
undetectable		 2ejtA-4us5A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbo RHODOPSIN KINASE

(Bos taurus) 		PF00069
(Pkinase)
PF00615
(RGS) 		3 ARG A 313
ASP A 332
ASP A 271
 None
 0.87A 2ejtA-4wboA:
undetectable		 2ejtA-4wboA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E

(Streptococcus
mutans) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ARG A 173
ASP A 178
ASP A 185
 None
 0.85A 2ejtA-4xb3A:
undetectable		 2ejtA-4xb3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypl LON PROTEASE

(Meiothermus
taiwanensis) 		PF00004
(AAA)
PF05362
(Lon_C) 		3 ARG A 272
ASP A 457
ASP A 453
 None
 0.75A 2ejtA-4yplA:
undetectable		 2ejtA-4yplA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zsl MITOGEN-ACTIVATED
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		3 ARG A 181
ASP A 200
ASP A 143
 None
 0.80A 2ejtA-4zslA:
undetectable		 2ejtA-4zslA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE

(Vesicular
stomatitis
virus) 		PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap) 		3 ARG A 728
ASP A2023
ASP A2018
 None
 0.88A 2ejtA-5a22A:
8.0		 2ejtA-5a22A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ayu IG VH,ANTI-LYSOZYME

(Mus musculus) 		PF07686
(V-set) 		3 ARG H  71
ASP H  27
ASP H 101
 None
 0.87A 2ejtA-5ayuH:
undetectable		 2ejtA-5ayuH:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az4 FLAGELLAR HOOK
SUBUNIT PROTEIN

(Campylobacter
jejuni) 		PF07196
(Flagellin_IN)
PF07559
(FlaE) 		3 ARG A 684
ASP A 235
ASP A 505
 None
 0.67A 2ejtA-5az4A:
undetectable		 2ejtA-5az4A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyb DNA-BINDING PROTEIN
REB1

(Schizosaccharomyces
pombe) 		PF00249
(Myb_DNA-binding) 		3 ARG A 340
ASP A 348
ASP A 355
 None
 0.88A 2ejtA-5eybA:
undetectable		 2ejtA-5eybA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5v PRP38
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		PF03371
(PRP38)
PF06991
(MFAP1) 		3 ARG A 117
ASP B 220
ASP B 222
 None
 0.81A 2ejtA-5f5vA:
undetectable		 2ejtA-5f5vA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7s GLYCOSIDE HYDROLASE
FAMILY 31

(Trueperella
pyogenes) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 ARG A 484
ASP A 253
ASP A 193
 None
 0.72A 2ejtA-5f7sA:
undetectable		 2ejtA-5f7sA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF15711
(ILEI) 		3 ARG A 129
ASP A 157
ASP A 187
 EDO  A 305 ( 3.6A)
None
None
 0.63A 2ejtA-5ggkA:
undetectable		 2ejtA-5ggkA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7j ELONGATION FACTOR 2

(Pyrococcus
horikoshii) 		no annotation 3 ARG A 651
ASP A 103
ASP A 107
 None
 0.77A 2ejtA-5h7jA:
undetectable		 2ejtA-5h7jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idq SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Burkholderia
vietnamiensis) 		PF00106
(adh_short) 		3 ARG A  22
ASP A  72
ASP A 120
 None
 0.89A 2ejtA-5idqA:
5.1		 2ejtA-5idqA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jd5 MGS-MILE3

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		3 ARG A 185
ASP A 142
ASP A  77
 None
 0.87A 2ejtA-5jd5A:
undetectable		 2ejtA-5jd5A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jzw AEROLYSIN

(Aeromonas
hydrophila) 		PF01117
(Aerolysin)
PF03440
(APT) 		3 ARG A 356
ASP A 311
ASP A 180
 None
 0.84A 2ejtA-5jzwA:
undetectable		 2ejtA-5jzwA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kov CAPSID POLYPROTEIN
VP90
PL-2 SCFV CHAIN

(Mamastrovirus
1;
Mus musculus) 		PF12226
(Astro_capsid_p)
PF07686
(V-set) 		3 ARG A 610
ASP A 465
ASP C  31
 None
 0.52A 2ejtA-5kovA:
undetectable		 2ejtA-5kovA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc2 PROTEIN FAM3C

(Homo sapiens) 		PF15711
(ILEI) 		3 ARG A 179
ASP A 123
ASP A 128
 None
 0.77A 2ejtA-5lc2A:
undetectable		 2ejtA-5lc2A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m22 HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT

(Sphingomonas
sp. TTNP3;
Sphingomonas
sp. TTNP3) 		no annotation
no annotation 		3 ARG B 109
ASP B 279
ASP A  23
 None
 0.72A 2ejtA-5m22B:
undetectable		 2ejtA-5m22B:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqs BETA-L-ARABINOBIOSID
ASE

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2) 		3 ARG A 512
ASP A 491
ASP A 494
 None
 0.87A 2ejtA-5mqsA:
undetectable		 2ejtA-5mqsA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1

(Glycine max) 		no annotation 3 ARG A 831
ASP A 613
ASP A 607
 None
 0.89A 2ejtA-5tr0A:
undetectable		 2ejtA-5tr0A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3c CTP SYNTHASE

(Escherichia
coli) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		3 ARG A 211
ASP A  72
ASP A  42
 ADP  A 602 (-3.4A)
ADP  A 602 (-3.8A)
None
 0.83A 2ejtA-5u3cA:
undetectable		 2ejtA-5u3cA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7q RHO-ASSOCIATED
PROTEIN KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		3 ARG A 213
ASP A 232
ASP A 176
 None
 0.83A 2ejtA-5u7qA:
undetectable		 2ejtA-5u7qA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uso PROTECTION OF
TELOMERES PROTEIN 1

(Schizosaccharomyces
pombe) 		no annotation 3 ARG A  59
ASP A  87
ASP A 124
 None
 0.57A 2ejtA-5usoA:
undetectable		 2ejtA-5usoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uyt ICE-BINDING PROTEIN

(Flavobacteriaceae
bacterium
3519-10) 		no annotation 3 ARG A 221
ASP A  53
ASP A  73
 None
 0.86A 2ejtA-5uytA:
undetectable		 2ejtA-5uytA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x3e KINESIN-LIKE PROTEIN

(Caenorhabditis
elegans) 		PF00225
(Kinesin) 		3 ARG A 242
ASP A 249
ASP A 223
 SO4  A 512 (-4.2A)
None
None
 0.68A 2ejtA-5x3eA:
undetectable		 2ejtA-5x3eA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yac TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5B

(Pyrococcus
abyssi) 		PF02475
(Met_10) 		3 ARG A 173
ASP A 211
ASP A 238
 None
 0.52A 2ejtA-5yacA:
18.5		 2ejtA-5yacA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS

(Escherichia
coli) 		no annotation 3 ARG A  90
ASP A  98
ASP A 101
 None
 0.80A 2ejtA-6anrA:
undetectable		 2ejtA-6anrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6h20 -

(-) 		no annotation 3 ARG A 325
ASP A 181
ASP A 250
 None
None
ASN  A 401 (-2.9A)
 0.85A 2ejtA-6h20A:
undetectable		 2ejtA-6h20A:
undetectable