SIMILAR PATTERNS OF AMINO ACIDS FOR 2DU8_J_BEZJ3352_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwu | ENOYL ACP REDUCTASE (Brassica napus) |
PF13561(adh_short_C2) | 4 | TYR A 188TYR A 198ILE A 244GLY A 234 | TDB A 502 (-3.2A)TDB A 502 (-4.5A)NoneNone | 1.13A | 2du8J-1cwuA:4.6 | 2du8J-1cwuA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbw | ENDO-1,4-BETA-GLUCANASE F ([Clostridium]cellulolyticum) |
PF02011(Glyco_hydro_48) | 4 | TYR A 382TYR A 275ILE A 314GLY A 380 | NoneGLC A3095 (-4.7A)GLC A3095 ( 4.6A)None | 1.31A | 2du8J-1fbwA:undetectable | 2du8J-1fbwA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fs2 | SKP2 (Homo sapiens) |
PF12937(F-box-like) | 4 | TYR A 358ILE A 382ARG A 306GLY A 304 | None | 1.28A | 2du8J-1fs2A:undetectable | 2du8J-1fs2A:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h14 | ENDO-1,4-BETA-XYLANASE (Pseudoalteromonashaloplanktis) |
PF01270(Glyco_hydro_8) | 4 | TYR A 53TYR A 63ILE A 75GLY A 132 | None | 1.04A | 2du8J-1h14A:undetectable | 2du8J-1h14A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1itx | GLYCOSYL HYDROLASE (Bacilluscirculans) |
PF00704(Glyco_hydro_18) | 4 | TYR A 60TYR A 50ILE A 73GLY A 437 | None | 1.35A | 2du8J-1itxA:undetectable | 2du8J-1itxA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jed | SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 4 | TYR A 473ILE A 398ARG A 391GLY A 507 | None | 1.07A | 2du8J-1jedA:2.1 | 2du8J-1jedA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nhw | ENOYL-ACYL CARRIERREDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 4 | TYR A 267TYR A 277ILE A 323GLY A 313 | TCC A 600 ( 4.0A)TCC A 600 (-4.5A)TCC A 600 (-4.8A)None | 1.06A | 2du8J-1nhwA:2.8 | 2du8J-1nhwA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1noz | DNA POLYMERASE (Escherichiavirus T4) |
PF03104(DNA_pol_B_exo1) | 4 | TYR A 95TYR A 5ILE A 8GLY A 96 | None | 1.27A | 2du8J-1nozA:undetectable | 2du8J-1nozA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4f | RNA-DEPENDENT RNAPOLYMERASE (Pestivirus A) |
PF00998(RdRP_3) | 4 | TYR A 256ILE A 380ARG A 399GLY A 401 | None | 1.02A | 2du8J-1s4fA:undetectable | 2du8J-1s4fA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vff | BETA-GLUCOSIDASE (Pyrococcushorikoshii) |
PF00232(Glyco_hydro_1) | 4 | TYR A 359TYR A 399ILE A 402GLY A 358 | None | 1.33A | 2du8J-1vffA:undetectable | 2du8J-1vffA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cxi | PHENYLALANYL-TRNASYNTHETASE BETACHAIN (Pyrococcushorikoshii) |
PF03483(B3_4)PF03484(B5) | 4 | TYR A 103TYR A 268ILE A 273GLY A 237 | None | 1.30A | 2du8J-2cxiA:undetectable | 2du8J-2cxiA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dul | N(2),N(2)-DIMETHYLGUANOSINE TRNAMETHYLTRANSFERASE (Pyrococcushorikoshii) |
PF02005(TRM) | 4 | TYR A 273ILE A 250ARG A 188GLY A 189 | None | 1.25A | 2du8J-2dulA:3.5 | 2du8J-2dulA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exh | BETA-D-XYLOSIDASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43) | 4 | TYR A 41ILE A 27ARG A 384GLY A 11 | None | 1.16A | 2du8J-2exhA:undetectable | 2du8J-2exhA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2foi | ENOYL-ACYL CARRIERREDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 4 | TYR A 267TYR A 277ILE A 323GLY A 313 | JPA A 500 (-3.7A)JPA A 500 (-4.4A)JPA A 500 (-4.1A)NAD A 450 (-4.9A) | 1.03A | 2du8J-2foiA:2.7 | 2du8J-2foiA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fzv | PUTATIVE ARSENICALRESISTANCE PROTEIN (Shigellaflexneri) |
PF03358(FMN_red) | 4 | TYR A 195ILE A 198ARG A 188GLY A 187 | None | 0.99A | 2du8J-2fzvA:2.4 | 2du8J-2fzvA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEALPHA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF01571(GCV_T)PF07992(Pyr_redox_2)PF08669(GCV_T_C)PF13510(Fer2_4) | 4 | TYR A 279ILE A 64ARG A 6GLY A 280 | None | 1.31A | 2du8J-2gahA:8.3 | 2du8J-2gahA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7t | TRANSCRIPTIONALREGULATOR (Corynebacteriumglutamicum) |
PF00440(TetR_N) | 4 | TYR A 149TYR A 179ILE A 156GLY A 147 | NoneNoneNoneUNL A 200 ( 4.4A) | 1.35A | 2du8J-2o7tA:undetectable | 2du8J-2o7tA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ol3 | ALLOGENEIC H-2KBM8MHC CLASS I MOLECULE (Mus musculus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | TYR H 85TYR H 118ILE H 95GLY H 83 | None | 1.15A | 2du8J-2ol3H:undetectable | 2du8J-2ol3H:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5u | UDP-GLUCOSE4-EPIMERASE (Thermusthermophilus) |
PF01370(Epimerase) | 4 | TYR A 217TYR A 174ILE A 300GLY A 245 | None | 1.04A | 2du8J-2p5uA:5.1 | 2du8J-2p5uA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q03 | UNCHARACTERIZEDPROTEIN (Shewanelladenitrificans) |
PF11528(DUF3224) | 4 | TYR A 42TYR A 130ILE A 132GLY A 48 | None | 1.00A | 2du8J-2q03A:undetectable | 2du8J-2q03A:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2va8 | SKI2-TYPE HELICASE (Sulfolobussolfataricus) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | TYR A 237ILE A 353ARG A 350GLY A 246 | None | 1.07A | 2du8J-2va8A:undetectable | 2du8J-2va8A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 4 | TYR A 423TYR A 402ILE A 400GLY A 432 | None | 1.14A | 2du8J-2y3sA:undetectable | 2du8J-2y3sA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y8v | CLASS III CHITINASE,PUTATIVE (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 4 | TYR A 223TYR A 208ILE A 211GLY A 224 | None | 1.04A | 2du8J-2y8vA:undetectable | 2du8J-2y8vA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzr | PYRIDOXALBIOSYNTHESIS LYASEPDXS (Methanocaldococcusjannaschii) |
PF01680(SOR_SNZ)PF05690(ThiG) | 4 | TYR A 116TYR A 216ILE A 224GLY A 141 | None | 0.96A | 2du8J-2yzrA:undetectable | 2du8J-2yzrA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbm | PROTEIN-TYROSINE-PHOSPHATASE (Shewanella sp.) |
PF00149(Metallophos) | 4 | TYR A 257TYR A 260ILE A 273GLY A 253 | None | 1.18A | 2du8J-2zbmA:undetectable | 2du8J-2zbmA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3am3 | ENOYL-ACP REDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 4 | TYR A 267TYR A 277ILE A 323GLY A 313 | TCL A 802 (-3.6A)TCL A 802 (-4.4A)NoneNAD A 801 (-4.8A) | 1.04A | 2du8J-3am3A:4.4 | 2du8J-3am3A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bga | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | TYR A 563TYR A 549ILE A 578GLY A 559 | None | 1.36A | 2du8J-3bgaA:undetectable | 2du8J-3bgaA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dec | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | TYR A 539TYR A 525ILE A 554GLY A 535 | None | 1.34A | 2du8J-3decA:undetectable | 2du8J-3decA:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwk | PENICILLIN-BINDINGPROTEIN 2 (Staphylococcusaureus) |
PF00905(Transpeptidase)PF00912(Transgly) | 4 | TYR A 240ILE A 239ARG A 93GLY A 200 | NoneNoneSO4 A 22 (-3.5A)None | 1.30A | 2du8J-3dwkA:undetectable | 2du8J-3dwkA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efv | PUTATIVESUCCINATE-SEMIALDEHYDE DEHYDROGENASE (Salmonellaenterica) |
PF00171(Aldedh) | 4 | TYR A 157TYR A 186ILE A 172GLY A 146 | None | 1.36A | 2du8J-3efvA:3.4 | 2du8J-3efvA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehm | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF12741(SusD-like) | 4 | TYR A 277TYR A 440ILE A 62GLY A 276 | None | 1.32A | 2du8J-3ehmA:undetectable | 2du8J-3ehmA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ek5 | URIDYLATE KINASE (Xanthomonascampestris) |
PF00696(AA_kinase) | 4 | TYR A 186ILE A 151ARG A 239GLY A 238 | None | 1.37A | 2du8J-3ek5A:2.9 | 2du8J-3ek5A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewi | N-ACYLNEURAMINATECYTIDYLYLTRANSFERASE (Mus musculus) |
no annotation | 4 | TYR A 26ILE A 25ARG A 145GLY A 144 | None | 1.24A | 2du8J-3ewiA:4.5 | 2du8J-3ewiA:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f4b | ENOYL-ACYL CARRIERPROTEIN REDUCTASE (Plasmodiumberghei) |
PF13561(adh_short_C2) | 4 | TYR A 252TYR A 262ILE A 308GLY A 298 | TCL A 400 (-3.6A)TCL A 400 (-4.7A)NoneNAD A 450 (-4.9A) | 1.12A | 2du8J-3f4bA:4.4 | 2du8J-3f4bA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3flb | RIFR (Amycolatopsismediterranei) |
PF00975(Thioesterase) | 4 | TYR A 54ILE A 69ARG A 57GLY A 30 | None | 1.16A | 2du8J-3flbA:undetectable | 2du8J-3flbA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gec | PERIOD CIRCADIANPROTEIN (Drosophilamelanogaster) |
PF00989(PAS)PF14598(PAS_11) | 4 | TYR A 264ILE A 258ARG A 272GLY A 271 | None | 1.01A | 2du8J-3gecA:undetectable | 2du8J-3gecA:24.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hwk | METHYLCITRATESYNTHASE (Mycobacteriumtuberculosis) |
PF00285(Citrate_synt) | 4 | TYR A 340ILE A 346ARG A 309GLY A 257 | None | 1.04A | 2du8J-3hwkA:undetectable | 2du8J-3hwkA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jts | MHC CLASS IMAMU-A*02 (Macaca mulatta) |
PF00129(MHC_I)PF07654(C1-set) | 4 | TYR A 85TYR A 118ILE A 95GLY A 83 | None | 1.23A | 2du8J-3jtsA:undetectable | 2du8J-3jtsA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1g | PUTATIVE GLUTATHIONES-TRANSFERASE (Corynebacteriumglutamicum) |
PF13409(GST_N_2)PF13410(GST_C_2) | 4 | TYR A 276ILE A 238ARG A 327GLY A 275 | None | 1.32A | 2du8J-3m1gA:undetectable | 2du8J-3m1gA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdu | N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE (Pseudomonasaeruginosa) |
PF01979(Amidohydro_1) | 4 | TYR A 159ILE A 177ARG A 209GLY A 163 | NoneNoneNGQ A 455 (-3.1A)None | 1.31A | 2du8J-3mduA:undetectable | 2du8J-3mduA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n54 | SPORE GERMINATIONPROTEIN B3 (Bacillussubtilis) |
PF05504(Spore_GerAC) | 4 | TYR B 182TYR B 189ILE B 191GLY B 177 | None | 1.11A | 2du8J-3n54B:undetectable | 2du8J-3n54B:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n5m | ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE (Bacillusanthracis) |
PF00202(Aminotran_3) | 4 | TYR A 128TYR A 127ILE A 299GLY A 246 | None | 1.12A | 2du8J-3n5mA:undetectable | 2du8J-3n5mA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opu | SPAP (Streptococcusmutans) |
PF16364(Antigen_C) | 4 | TYR A1361ILE A1457ARG A1461GLY A1389 | None | 1.22A | 2du8J-3opuA:undetectable | 2du8J-3opuA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p14 | L-RHAMNOSE ISOMERASE (Bacillushalodurans) |
PF06134(RhaA) | 4 | TYR A 409ILE A 406ARG A 417GLY A 65 | None | 1.11A | 2du8J-3p14A:undetectable | 2du8J-3p14A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3plr | UDP-GLUCOSE6-DEHYDROGENASE (Klebsiellapneumoniae) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | TYR A 380ILE A 291ARG A 283GLY A 248 | None | 1.19A | 2du8J-3plrA:4.1 | 2du8J-3plrA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3plr | UDP-GLUCOSE6-DEHYDROGENASE (Klebsiellapneumoniae) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | TYR A 380ILE A 364ARG A 283GLY A 248 | None | 1.33A | 2du8J-3plrA:4.1 | 2du8J-3plrA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4n | UNCHARACTERIZEDPROTEIN MJ0754 (Methanocaldococcusjannaschii) |
PF09968(DUF2202) | 4 | TYR A 161TYR A 171ILE A 166GLY A 109 | None | 1.22A | 2du8J-3q4nA:undetectable | 2du8J-3q4nA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4n | UNCHARACTERIZEDPROTEIN MJ0754 (Methanocaldococcusjannaschii) |
PF09968(DUF2202) | 4 | TYR A 161TYR A 171ILE A 174GLY A 109 | None | 1.21A | 2du8J-3q4nA:undetectable | 2du8J-3q4nA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4o | UNCHARACTERIZEDPROTEIN MJ0754 (Methanocaldococcusjannaschii) |
PF09968(DUF2202) | 4 | TYR A 161TYR A 171ILE A 166GLY A 109 | None | 1.19A | 2du8J-3q4oA:undetectable | 2du8J-3q4oA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4o | UNCHARACTERIZEDPROTEIN MJ0754 (Methanocaldococcusjannaschii) |
PF09968(DUF2202) | 4 | TYR A 161TYR A 171ILE A 174GLY A 109 | None | 1.17A | 2du8J-3q4oA:undetectable | 2du8J-3q4oA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsm | OCCLUSION-DERIVEDVIRUS ENVELOPEPROTEIN E66 (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF04850(Baculo_E66) | 4 | TYR A 288TYR A 297ILE A 328GLY A 281 | None | 1.35A | 2du8J-3vsmA:undetectable | 2du8J-3vsmA:19.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w4k | D-AMINO-ACID OXIDASE (Homo sapiens) |
PF01266(DAO) | 4 | TYR A 228ILE A 230ARG A 283GLY A 313 | 3LD A 402 (-3.8A)None3LD A 402 (-3.7A)3LD A 402 ( 3.6A) | 0.29A | 2du8J-3w4kA:54.9 | 2du8J-3w4kA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4crm | EUKARYOTIC PEPTIDECHAIN RELEASE FACTORSUBUNIT 1 (Saccharomycescerevisiae) |
PF03464(eRF1_2)PF03465(eRF1_3) | 4 | TYR X 198ILE X 146ARG X 195GLY X 150 | None | 1.30A | 2du8J-4crmX:undetectable | 2du8J-4crmX:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dgk | PHYTOENEDEHYDROGENASE (Pantoeaananatis) |
PF01593(Amino_oxidase) | 4 | TYR A 136TYR A 201ILE A 204GLY A 135 | None | 1.31A | 2du8J-4dgkA:10.4 | 2du8J-4dgkA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fir | PYRIDOXALBIOSYNTHESIS LYASEPDXS (Pyrococcushorikoshii) |
PF01680(SOR_SNZ)PF05690(ThiG) | 4 | TYR A 123TYR A 223ILE A 231GLY A 148 | None | 0.99A | 2du8J-4firA:undetectable | 2du8J-4firA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4flm | S-FORMYLGLUTATHIONEHYDROLASE (Saccharomycescerevisiae) |
PF00756(Esterase) | 4 | TYR A 111TYR A 165ILE A 189GLY A 109 | NoneNoneSDP A 161 ( 4.7A)None | 1.01A | 2du8J-4flmA:undetectable | 2du8J-4flmA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fus | RTX TOXINS ANDRELATED CA2+-BINDINGPROTEIN (Hahellachejuensis) |
PF02011(Glyco_hydro_48) | 4 | TYR A 416TYR A 304ILE A 348GLY A 414 | NoneGOL A 806 (-4.8A)NoneOHI A 352 ( 3.5A) | 1.36A | 2du8J-4fusA:undetectable | 2du8J-4fusA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gb7 | 6-AMINOHEXANOATE-DIMER HYDROLASE (Bacillusanthracis) |
PF00144(Beta-lactamase) | 4 | TYR A 403TYR A 407ILE A 386GLY A 373 | None | 1.19A | 2du8J-4gb7A:undetectable | 2du8J-4gb7A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkp | SPINDLE POLEBODY-ASSOCIATEDPROTEIN VIK1 ([Candida]glabrata) |
PF16796(Microtub_bd) | 4 | TYR A 518TYR A 483ILE A 492GLY A 398 | None | 1.34A | 2du8J-4gkpA:undetectable | 2du8J-4gkpA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jf7 | HEMAGGLUTININ-NEURAMINIDASE (Mammalianrubulavirus 5) |
no annotation | 4 | TYR D 463TYR D 523ILE D 164GLY D 391 | None | 1.05A | 2du8J-4jf7D:undetectable | 2du8J-4jf7D:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx8 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] FABI (Escherichiacoli) |
PF13561(adh_short_C2) | 4 | TYR A 146TYR A 156ILE A 200GLY A 190 | AE6 A 301 ( 4.0A)AE6 A 301 (-3.8A)AE6 A 301 (-4.2A)None | 1.33A | 2du8J-4jx8A:4.4 | 2du8J-4jx8A:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lx4 | ENDOGLUCANASE(ENDO-1,4-BETA-GLUCANASE)PROTEIN (Pseudomonasstutzeri) |
PF00150(Cellulase) | 4 | TYR A 46TYR A 47ILE A 296GLY A 301 | None | 1.31A | 2du8J-4lx4A:undetectable | 2du8J-4lx4A:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0v | EXONUCLEASE SUBUNITSBCD (Escherichiacoli) |
PF00149(Metallophos)PF12320(SbcD_C) | 4 | TYR A 161TYR A 160ILE A 137GLY A 183 | None | 1.06A | 2du8J-4m0vA:undetectable | 2du8J-4m0vA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m87 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Neisseriameningitidis) |
PF13561(adh_short_C2) | 4 | TYR A 147TYR A 157ILE A 201GLY A 191 | NAD A 301 ( 4.9A)NoneNoneNone | 1.22A | 2du8J-4m87A:4.7 | 2du8J-4m87A:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mmh | HEPARINASE IIIPROTEIN (Pedobacterheparinus) |
PF07940(Hepar_II_III)PF16889(Hepar_II_III_N) | 4 | TYR A 306TYR A 322ILE A 270GLY A 307 | None | 1.16A | 2du8J-4mmhA:undetectable | 2du8J-4mmhA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nk5 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (CandidatusLiberibacterasiaticus) |
PF13561(adh_short_C2) | 4 | TYR A 146TYR A 156ILE A 200GLY A 190 | None | 1.18A | 2du8J-4nk5A:4.2 | 2du8J-4nk5A:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oic | BET V IALLERGEN-LIKE (Oryza sativa) |
PF10604(Polyketide_cyc2) | 4 | TYR A 73ILE A 63ARG A 94GLY A 68 | None | 1.10A | 2du8J-4oicA:undetectable | 2du8J-4oicA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rjk | ACETOLACTATESYNTHASE (Bacillussubtilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | TYR A 287TYR A 319ILE A 305GLY A 219 | None | 1.30A | 2du8J-4rjkA:undetectable | 2du8J-4rjkA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr4 | TYPE IIIIODOTHYRONINEDEIODINASE (Mus musculus) |
PF00837(T4_deiodinase) | 4 | TYR A 262ILE A 269ARG A 275GLY A 274 | None | 1.22A | 2du8J-4tr4A:2.5 | 2du8J-4tr4A:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wz9 | AGAP004809-PA (Anophelesgambiae) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | TYR A 740TYR A 708ILE A 731GLY A 739 | None | 1.11A | 2du8J-4wz9A:undetectable | 2du8J-4wz9A:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xeu | TRANSKETOLASE (Pseudomonasaeruginosa) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | TYR A 589TYR A 622ILE A 555GLY A 539 | None | 1.24A | 2du8J-4xeuA:3.1 | 2du8J-4xeuA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhj | ENVELOPEGLYCOPROTEIN H (Humanalphaherpesvirus3) |
PF02489(Herpes_glycop_H)PF17488(Herpes_glycoH_C) | 4 | TYR A 364TYR A 365ILE A 271GLY A 248 | None | 1.03A | 2du8J-4xhjA:undetectable | 2du8J-4xhjA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwl | EXOGLUCANASE S (Clostridiumcellulovorans) |
PF02011(Glyco_hydro_48) | 4 | TYR A 374TYR A 267ILE A 306GLY A 372 | None | 1.32A | 2du8J-4xwlA:undetectable | 2du8J-4xwlA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yfl | 1B2530 LIGHT CHAIN (Homo sapiens) |
no annotation | 4 | TYR L 91TYR L 32ARG L 96GLY L 95 | None | 1.15A | 2du8J-4yflL:undetectable | 2du8J-4yflL:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwj | CHIMERA PROTEIN OFHUMAN RHODOPSIN,MOUSE S-ARRESTIN,AND T4 ENDOLYSIN (Homo sapiens;Mus musculus;Escherichiavirus T4) |
PF00001(7tm_1)PF00339(Arrestin_N)PF00959(Phage_lysozyme)PF02752(Arrestin_C)PF10413(Rhodopsin_N) | 4 | TYR A 192TYR A 191ILE A 189GLY A 182 | None | 1.15A | 2du8J-4zwjA:undetectable | 2du8J-4zwjA:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cg0 | BETA-GLUCOSIDASE (Spodopterafrugiperda) |
PF00232(Glyco_hydro_1) | 4 | TYR A 441TYR A 483ILE A 486GLY A 440 | None | 1.32A | 2du8J-5cg0A:undetectable | 2du8J-5cg0A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fca | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3A (Mus musculus) |
PF00149(Metallophos) | 4 | TYR A 337TYR A 245ILE A 202GLY A 340 | None | 1.31A | 2du8J-5fcaA:undetectable | 2du8J-5fcaA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fx8 | LINOLEATE11-LIPOXYGENASE (Gaeumannomycesavenae) |
PF00305(Lipoxygenase) | 4 | TYR A 83TYR A 326ILE A 92GLY A 73 | None | 1.17A | 2du8J-5fx8A:undetectable | 2du8J-5fx8A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2h | O-METHYLTRANSFERASEFAMILY 2 (Planctopiruslimnophila) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 4 | TYR A 327TYR A 332ILE A 296GLY A 324 | None | 1.37A | 2du8J-5i2hA:3.1 | 2du8J-5i2hA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6s | ENDOGLUCANASE (Talaromycesverruculosus) |
PF00150(Cellulase) | 4 | TYR A 209TYR A 293ILE A 292GLY A 214 | None | 1.36A | 2du8J-5i6sA:undetectable | 2du8J-5i6sA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iq6 | RNA DEPENDENT RNAPOLYMERASE (Dengue virus) |
PF00972(Flavi_NS5) | 4 | TYR A 299TYR A 304ILE A 591ARG A 581 | None | 1.30A | 2du8J-5iq6A:undetectable | 2du8J-5iq6A:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iuy | MULTIDRUG EFFLUXOUTER MEMBRANEPROTEIN OPRN (Pseudomonasaeruginosa) |
PF02321(OEP) | 4 | TYR A 369TYR A 25ILE A 255GLY A 431 | None | 1.07A | 2du8J-5iuyA:undetectable | 2du8J-5iuyA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jsi | BACTERIORHODOPSIN (CandidatusActinomarinaminuta) |
PF01036(Bac_rhodopsin) | 4 | TYR A 70ILE A 109ARG A 188GLY A 175 | NoneLYR A 200 ( 4.8A)IOD A 316 (-3.6A)None | 1.22A | 2du8J-5jsiA:undetectable | 2du8J-5jsiA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jt8 | BLO T 1 ALLERGEN (Blomiatropicalis) |
PF00112(Peptidase_C1)PF08246(Inhibitor_I29) | 4 | TYR A 242TYR A 52ILE A 47GLY A 253 | NO3 A 405 (-4.5A)NoneNoneNone | 1.36A | 2du8J-5jt8A:undetectable | 2du8J-5jt8A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koi | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Brucellaabortus) |
PF13561(adh_short_C2) | 4 | TYR A 147TYR A 157ILE A 201GLY A 191 | NAD A 300 ( 4.8A)NoneNoneNone | 1.15A | 2du8J-5koiA:5.4 | 2du8J-5koiA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koj | NITROGENASE PROTEINALPHA CHAIN (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro) | 4 | TYR A 370TYR A 417ILE A 416GLY A 372 | NoneNoneNoneICS A 502 (-3.5A) | 1.21A | 2du8J-5kojA:2.8 | 2du8J-5kojA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koj | NITROGENASE PROTEINALPHA CHAIN (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro) | 4 | TYR A 395TYR A 403ILE A 416GLY A 372 | NoneNoneNoneICS A 502 (-3.5A) | 1.28A | 2du8J-5kojA:2.8 | 2du8J-5kojA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lvy | ADHESIN PROTEIN (Escherichiacoli) |
no annotation | 4 | TYR A 115TYR A 120ILE A 159GLY A 114 | None | 1.32A | 2du8J-5lvyA:undetectable | 2du8J-5lvyA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ngh | ODORANT BINDINGPROTEIN 3 (Ailuropodamelanoleuca) |
no annotation | 4 | TYR A 19ILE A 46ARG A 163GLY A 164 | None | 1.27A | 2du8J-5nghA:undetectable | 2du8J-5nghA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5suo | EXTRACELLULARSOLUTE-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF12010(DUF3502) | 4 | TYR A 115TYR A 106ILE A 107GLY A 113 | None | 1.10A | 2du8J-5suoA:undetectable | 2du8J-5suoA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5van | BETA-KLOTHO (Homo sapiens) |
no annotation | 4 | TYR A 457TYR A 499ILE A 502GLY A 456 | None | 1.30A | 2du8J-5vanA:undetectable | 2du8J-5vanA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wi9 | - (-) |
no annotation | 4 | TYR A 457TYR A 499ILE A 502GLY A 456 | None | 1.31A | 2du8J-5wi9A:undetectable | 2du8J-5wi9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wlz | DNA REPAIR PROTEINXRCC4,MYOSIN-7 (Homo sapiens) |
no annotation | 4 | TYR C 84TYR C 94ILE C 34GLY C 77 | None | 1.30A | 2du8J-5wlzC:undetectable | 2du8J-5wlzC:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xd7 | 3,6-ANHYDRO-ALPHA-L-GALACTONATECYCLOISOMERASE (Vibrio sp. EJY3) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TYR A 52TYR A 50ILE A 110GLY A 301 | None | 1.11A | 2du8J-5xd7A:undetectable | 2du8J-5xd7A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsx | CHITINASE (Thermococcuschitonophagus) |
no annotation | 4 | TYR A 431ILE A 471ARG A 425GLY A 426 | None | 1.14A | 2du8J-5xsxA:undetectable | 2du8J-5xsxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yj6 | DOCKERIN TYPE IREPEAT-CONTAININGPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 4 | TYR A 410TYR A 302ILE A 342GLY A 408 | None | 1.29A | 2du8J-5yj6A:undetectable | 2du8J-5yj6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cr0 | (S)-6-HYDROXYNICOTINE OXIDASE (Shinella sp.HZN7) |
no annotation | 4 | TYR A 367ILE A 56ARG A 37GLY A 42 | NoneNoneFAD A 507 (-4.4A)FAD A 507 (-3.1A) | 1.32A | 2du8J-6cr0A:12.4 | 2du8J-6cr0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eo5 | PPBBE-LIKE 1 D396N (Physcomitrellapatens) |
no annotation | 4 | TYR A 472TYR A 471ILE A 462GLY A 229 | None | 1.36A | 2du8J-6eo5A:undetectable | 2du8J-6eo5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f34 | AMINO ACIDTRANSPORTER (Geobacilluskaustophilus) |
no annotation | 4 | TYR A 95TYR A 79ILE A 257GLY A 90 | None | 1.21A | 2du8J-6f34A:undetectable | 2du8J-6f34A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fah | CAFFEYL-COAREDUCTASE-ETFCOMPLEX SUBUNIT CARE (Acetobacteriumwoodii) |
no annotation | 4 | TYR A 155TYR A 129ILE A 107GLY A 153 | None | 1.38A | 2du8J-6fahA:3.0 | 2du8J-6fahA:undetectable |