SIMILAR PATTERNS OF AMINO ACIDS FOR 2DU8_J_BEZJ3352_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cwu ENOYL ACP REDUCTASE

(Brassica napus)
PF13561
(adh_short_C2)
4 TYR A 188
TYR A 198
ILE A 244
GLY A 234
TDB  A 502 (-3.2A)
TDB  A 502 (-4.5A)
None
None
1.13A 2du8J-1cwuA:
4.6
2du8J-1cwuA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbw ENDO-1,4-BETA-GLUCAN
ASE F


([Clostridium]
cellulolyticum)
PF02011
(Glyco_hydro_48)
4 TYR A 382
TYR A 275
ILE A 314
GLY A 380
None
GLC  A3095 (-4.7A)
GLC  A3095 ( 4.6A)
None
1.31A 2du8J-1fbwA:
undetectable
2du8J-1fbwA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fs2 SKP2

(Homo sapiens)
PF12937
(F-box-like)
4 TYR A 358
ILE A 382
ARG A 306
GLY A 304
None
1.28A 2du8J-1fs2A:
undetectable
2du8J-1fs2A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h14 ENDO-1,4-BETA-XYLANA
SE


(Pseudoalteromonas
haloplanktis)
PF01270
(Glyco_hydro_8)
4 TYR A  53
TYR A  63
ILE A  75
GLY A 132
None
1.04A 2du8J-1h14A:
undetectable
2du8J-1h14A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itx GLYCOSYL HYDROLASE

(Bacillus
circulans)
PF00704
(Glyco_hydro_18)
4 TYR A  60
TYR A  50
ILE A  73
GLY A 437
None
1.35A 2du8J-1itxA:
undetectable
2du8J-1itxA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jed SULFATE
ADENYLYLTRANSFERASE


(Saccharomyces
cerevisiae)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2)
4 TYR A 473
ILE A 398
ARG A 391
GLY A 507
None
1.07A 2du8J-1jedA:
2.1
2du8J-1jedA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nhw ENOYL-ACYL CARRIER
REDUCTASE


(Plasmodium
falciparum)
PF13561
(adh_short_C2)
4 TYR A 267
TYR A 277
ILE A 323
GLY A 313
TCC  A 600 ( 4.0A)
TCC  A 600 (-4.5A)
TCC  A 600 (-4.8A)
None
1.06A 2du8J-1nhwA:
2.8
2du8J-1nhwA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1noz DNA POLYMERASE

(Escherichia
virus T4)
PF03104
(DNA_pol_B_exo1)
4 TYR A  95
TYR A   5
ILE A   8
GLY A  96
None
1.27A 2du8J-1nozA:
undetectable
2du8J-1nozA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4f RNA-DEPENDENT RNA
POLYMERASE


(Pestivirus A)
PF00998
(RdRP_3)
4 TYR A 256
ILE A 380
ARG A 399
GLY A 401
None
1.02A 2du8J-1s4fA:
undetectable
2du8J-1s4fA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vff BETA-GLUCOSIDASE

(Pyrococcus
horikoshii)
PF00232
(Glyco_hydro_1)
4 TYR A 359
TYR A 399
ILE A 402
GLY A 358
None
1.33A 2du8J-1vffA:
undetectable
2du8J-1vffA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cxi PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN


(Pyrococcus
horikoshii)
PF03483
(B3_4)
PF03484
(B5)
4 TYR A 103
TYR A 268
ILE A 273
GLY A 237
None
1.30A 2du8J-2cxiA:
undetectable
2du8J-2cxiA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dul N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE


(Pyrococcus
horikoshii)
PF02005
(TRM)
4 TYR A 273
ILE A 250
ARG A 188
GLY A 189
None
1.25A 2du8J-2dulA:
3.5
2du8J-2dulA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exh BETA-D-XYLOSIDASE

(Geobacillus
stearothermophilus)
PF04616
(Glyco_hydro_43)
4 TYR A  41
ILE A  27
ARG A 384
GLY A  11
None
1.16A 2du8J-2exhA:
undetectable
2du8J-2exhA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2foi ENOYL-ACYL CARRIER
REDUCTASE


(Plasmodium
falciparum)
PF13561
(adh_short_C2)
4 TYR A 267
TYR A 277
ILE A 323
GLY A 313
JPA  A 500 (-3.7A)
JPA  A 500 (-4.4A)
JPA  A 500 (-4.1A)
NAD  A 450 (-4.9A)
1.03A 2du8J-2foiA:
2.7
2du8J-2foiA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN


(Shigella
flexneri)
PF03358
(FMN_red)
4 TYR A 195
ILE A 198
ARG A 188
GLY A 187
None
0.99A 2du8J-2fzvA:
2.4
2du8J-2fzvA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gah HETEROTETRAMERIC
SARCOSINE OXIDASE
ALPHA-SUBUNIT


(Stenotrophomonas
maltophilia)
PF01571
(GCV_T)
PF07992
(Pyr_redox_2)
PF08669
(GCV_T_C)
PF13510
(Fer2_4)
4 TYR A 279
ILE A  64
ARG A   6
GLY A 280
None
1.31A 2du8J-2gahA:
8.3
2du8J-2gahA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7t TRANSCRIPTIONAL
REGULATOR


(Corynebacterium
glutamicum)
PF00440
(TetR_N)
4 TYR A 149
TYR A 179
ILE A 156
GLY A 147
None
None
None
UNL  A 200 ( 4.4A)
1.35A 2du8J-2o7tA:
undetectable
2du8J-2o7tA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE


(Mus musculus)
PF00129
(MHC_I)
PF07654
(C1-set)
4 TYR H  85
TYR H 118
ILE H  95
GLY H  83
None
1.15A 2du8J-2ol3H:
undetectable
2du8J-2ol3H:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5u UDP-GLUCOSE
4-EPIMERASE


(Thermus
thermophilus)
PF01370
(Epimerase)
4 TYR A 217
TYR A 174
ILE A 300
GLY A 245
None
1.04A 2du8J-2p5uA:
5.1
2du8J-2p5uA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q03 UNCHARACTERIZED
PROTEIN


(Shewanella
denitrificans)
PF11528
(DUF3224)
4 TYR A  42
TYR A 130
ILE A 132
GLY A  48
None
1.00A 2du8J-2q03A:
undetectable
2du8J-2q03A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2va8 SKI2-TYPE HELICASE

(Sulfolobus
solfataricus)
PF00270
(DEAD)
PF00271
(Helicase_C)
4 TYR A 237
ILE A 353
ARG A 350
GLY A 246
None
1.07A 2du8J-2va8A:
undetectable
2du8J-2va8A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3s TAML

(Streptomyces
sp. 307-9)
PF01565
(FAD_binding_4)
PF08031
(BBE)
4 TYR A 423
TYR A 402
ILE A 400
GLY A 432
None
1.14A 2du8J-2y3sA:
undetectable
2du8J-2y3sA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8v CLASS III CHITINASE,
PUTATIVE


(Aspergillus
fumigatus)
PF00704
(Glyco_hydro_18)
4 TYR A 223
TYR A 208
ILE A 211
GLY A 224
None
1.04A 2du8J-2y8vA:
undetectable
2du8J-2y8vA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzr PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS


(Methanocaldococcus
jannaschii)
PF01680
(SOR_SNZ)
PF05690
(ThiG)
4 TYR A 116
TYR A 216
ILE A 224
GLY A 141
None
0.96A 2du8J-2yzrA:
undetectable
2du8J-2yzrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbm PROTEIN-TYROSINE-PHO
SPHATASE


(Shewanella sp.)
PF00149
(Metallophos)
4 TYR A 257
TYR A 260
ILE A 273
GLY A 253
None
1.18A 2du8J-2zbmA:
undetectable
2du8J-2zbmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3am3 ENOYL-ACP REDUCTASE

(Plasmodium
falciparum)
PF13561
(adh_short_C2)
4 TYR A 267
TYR A 277
ILE A 323
GLY A 313
TCL  A 802 (-3.6A)
TCL  A 802 (-4.4A)
None
NAD  A 801 (-4.8A)
1.04A 2du8J-3am3A:
4.4
2du8J-3am3A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981)
4 TYR A 563
TYR A 549
ILE A 578
GLY A 559
None
1.36A 2du8J-3bgaA:
undetectable
2du8J-3bgaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dec BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981)
4 TYR A 539
TYR A 525
ILE A 554
GLY A 535
None
1.34A 2du8J-3decA:
undetectable
2du8J-3decA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwk PENICILLIN-BINDING
PROTEIN 2


(Staphylococcus
aureus)
PF00905
(Transpeptidase)
PF00912
(Transgly)
4 TYR A 240
ILE A 239
ARG A  93
GLY A 200
None
None
SO4  A  22 (-3.5A)
None
1.30A 2du8J-3dwkA:
undetectable
2du8J-3dwkA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE


(Salmonella
enterica)
PF00171
(Aldedh)
4 TYR A 157
TYR A 186
ILE A 172
GLY A 146
None
1.36A 2du8J-3efvA:
3.4
2du8J-3efvA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehm SUSD HOMOLOG

(Bacteroides
thetaiotaomicron)
PF12741
(SusD-like)
4 TYR A 277
TYR A 440
ILE A  62
GLY A 276
None
1.32A 2du8J-3ehmA:
undetectable
2du8J-3ehmA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ek5 URIDYLATE KINASE

(Xanthomonas
campestris)
PF00696
(AA_kinase)
4 TYR A 186
ILE A 151
ARG A 239
GLY A 238
None
1.37A 2du8J-3ek5A:
2.9
2du8J-3ek5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewi N-ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE


(Mus musculus)
no annotation 4 TYR A  26
ILE A  25
ARG A 145
GLY A 144
None
1.24A 2du8J-3ewiA:
4.5
2du8J-3ewiA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f4b ENOYL-ACYL CARRIER
PROTEIN REDUCTASE


(Plasmodium
berghei)
PF13561
(adh_short_C2)
4 TYR A 252
TYR A 262
ILE A 308
GLY A 298
TCL  A 400 (-3.6A)
TCL  A 400 (-4.7A)
None
NAD  A 450 (-4.9A)
1.12A 2du8J-3f4bA:
4.4
2du8J-3f4bA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flb RIFR

(Amycolatopsis
mediterranei)
PF00975
(Thioesterase)
4 TYR A  54
ILE A  69
ARG A  57
GLY A  30
None
1.16A 2du8J-3flbA:
undetectable
2du8J-3flbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gec PERIOD CIRCADIAN
PROTEIN


(Drosophila
melanogaster)
PF00989
(PAS)
PF14598
(PAS_11)
4 TYR A 264
ILE A 258
ARG A 272
GLY A 271
None
1.01A 2du8J-3gecA:
undetectable
2du8J-3gecA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwk METHYLCITRATE
SYNTHASE


(Mycobacterium
tuberculosis)
PF00285
(Citrate_synt)
4 TYR A 340
ILE A 346
ARG A 309
GLY A 257
None
1.04A 2du8J-3hwkA:
undetectable
2du8J-3hwkA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jts MHC CLASS I
MAMU-A*02


(Macaca mulatta)
PF00129
(MHC_I)
PF07654
(C1-set)
4 TYR A  85
TYR A 118
ILE A  95
GLY A  83
None
1.23A 2du8J-3jtsA:
undetectable
2du8J-3jtsA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE


(Corynebacterium
glutamicum)
PF13409
(GST_N_2)
PF13410
(GST_C_2)
4 TYR A 276
ILE A 238
ARG A 327
GLY A 275
None
1.32A 2du8J-3m1gA:
undetectable
2du8J-3m1gA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE


(Pseudomonas
aeruginosa)
PF01979
(Amidohydro_1)
4 TYR A 159
ILE A 177
ARG A 209
GLY A 163
None
None
NGQ  A 455 (-3.1A)
None
1.31A 2du8J-3mduA:
undetectable
2du8J-3mduA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n54 SPORE GERMINATION
PROTEIN B3


(Bacillus
subtilis)
PF05504
(Spore_GerAC)
4 TYR B 182
TYR B 189
ILE B 191
GLY B 177
None
1.11A 2du8J-3n54B:
undetectable
2du8J-3n54B:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5m ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE


(Bacillus
anthracis)
PF00202
(Aminotran_3)
4 TYR A 128
TYR A 127
ILE A 299
GLY A 246
None
1.12A 2du8J-3n5mA:
undetectable
2du8J-3n5mA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opu SPAP

(Streptococcus
mutans)
PF16364
(Antigen_C)
4 TYR A1361
ILE A1457
ARG A1461
GLY A1389
None
1.22A 2du8J-3opuA:
undetectable
2du8J-3opuA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p14 L-RHAMNOSE ISOMERASE

(Bacillus
halodurans)
PF06134
(RhaA)
4 TYR A 409
ILE A 406
ARG A 417
GLY A  65
None
1.11A 2du8J-3p14A:
undetectable
2du8J-3p14A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3plr UDP-GLUCOSE
6-DEHYDROGENASE


(Klebsiella
pneumoniae)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
4 TYR A 380
ILE A 291
ARG A 283
GLY A 248
None
1.19A 2du8J-3plrA:
4.1
2du8J-3plrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3plr UDP-GLUCOSE
6-DEHYDROGENASE


(Klebsiella
pneumoniae)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
4 TYR A 380
ILE A 364
ARG A 283
GLY A 248
None
1.33A 2du8J-3plrA:
4.1
2du8J-3plrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4n UNCHARACTERIZED
PROTEIN MJ0754


(Methanocaldococcus
jannaschii)
PF09968
(DUF2202)
4 TYR A 161
TYR A 171
ILE A 166
GLY A 109
None
1.22A 2du8J-3q4nA:
undetectable
2du8J-3q4nA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4n UNCHARACTERIZED
PROTEIN MJ0754


(Methanocaldococcus
jannaschii)
PF09968
(DUF2202)
4 TYR A 161
TYR A 171
ILE A 174
GLY A 109
None
1.21A 2du8J-3q4nA:
undetectable
2du8J-3q4nA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4o UNCHARACTERIZED
PROTEIN MJ0754


(Methanocaldococcus
jannaschii)
PF09968
(DUF2202)
4 TYR A 161
TYR A 171
ILE A 166
GLY A 109
None
1.19A 2du8J-3q4oA:
undetectable
2du8J-3q4oA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4o UNCHARACTERIZED
PROTEIN MJ0754


(Methanocaldococcus
jannaschii)
PF09968
(DUF2202)
4 TYR A 161
TYR A 171
ILE A 174
GLY A 109
None
1.17A 2du8J-3q4oA:
undetectable
2du8J-3q4oA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66


(Autographa
californica
multiple
nucleopolyhedrovirus)
PF04850
(Baculo_E66)
4 TYR A 288
TYR A 297
ILE A 328
GLY A 281
None
1.35A 2du8J-3vsmA:
undetectable
2du8J-3vsmA:
19.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w4k D-AMINO-ACID OXIDASE

(Homo sapiens)
PF01266
(DAO)
4 TYR A 228
ILE A 230
ARG A 283
GLY A 313
3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
0.29A 2du8J-3w4kA:
54.9
2du8J-3w4kA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crm EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1


(Saccharomyces
cerevisiae)
PF03464
(eRF1_2)
PF03465
(eRF1_3)
4 TYR X 198
ILE X 146
ARG X 195
GLY X 150
None
1.30A 2du8J-4crmX:
undetectable
2du8J-4crmX:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dgk PHYTOENE
DEHYDROGENASE


(Pantoea
ananatis)
PF01593
(Amino_oxidase)
4 TYR A 136
TYR A 201
ILE A 204
GLY A 135
None
1.31A 2du8J-4dgkA:
10.4
2du8J-4dgkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fir PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS


(Pyrococcus
horikoshii)
PF01680
(SOR_SNZ)
PF05690
(ThiG)
4 TYR A 123
TYR A 223
ILE A 231
GLY A 148
None
0.99A 2du8J-4firA:
undetectable
2du8J-4firA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4flm S-FORMYLGLUTATHIONE
HYDROLASE


(Saccharomyces
cerevisiae)
PF00756
(Esterase)
4 TYR A 111
TYR A 165
ILE A 189
GLY A 109
None
None
SDP  A 161 ( 4.7A)
None
1.01A 2du8J-4flmA:
undetectable
2du8J-4flmA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fus RTX TOXINS AND
RELATED CA2+-BINDING
PROTEIN


(Hahella
chejuensis)
PF02011
(Glyco_hydro_48)
4 TYR A 416
TYR A 304
ILE A 348
GLY A 414
None
GOL  A 806 (-4.8A)
None
OHI  A 352 ( 3.5A)
1.36A 2du8J-4fusA:
undetectable
2du8J-4fusA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gb7 6-AMINOHEXANOATE-DIM
ER HYDROLASE


(Bacillus
anthracis)
PF00144
(Beta-lactamase)
4 TYR A 403
TYR A 407
ILE A 386
GLY A 373
None
1.19A 2du8J-4gb7A:
undetectable
2du8J-4gb7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkp SPINDLE POLE
BODY-ASSOCIATED
PROTEIN VIK1


([Candida]
glabrata)
PF16796
(Microtub_bd)
4 TYR A 518
TYR A 483
ILE A 492
GLY A 398
None
1.34A 2du8J-4gkpA:
undetectable
2du8J-4gkpA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jf7 HEMAGGLUTININ-NEURAM
INIDASE


(Mammalian
rubulavirus 5)
no annotation 4 TYR D 463
TYR D 523
ILE D 164
GLY D 391
None
1.05A 2du8J-4jf7D:
undetectable
2du8J-4jf7D:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jx8 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI


(Escherichia
coli)
PF13561
(adh_short_C2)
4 TYR A 146
TYR A 156
ILE A 200
GLY A 190
AE6  A 301 ( 4.0A)
AE6  A 301 (-3.8A)
AE6  A 301 (-4.2A)
None
1.33A 2du8J-4jx8A:
4.4
2du8J-4jx8A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN


(Pseudomonas
stutzeri)
PF00150
(Cellulase)
4 TYR A  46
TYR A  47
ILE A 296
GLY A 301
None
1.31A 2du8J-4lx4A:
undetectable
2du8J-4lx4A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0v EXONUCLEASE SUBUNIT
SBCD


(Escherichia
coli)
PF00149
(Metallophos)
PF12320
(SbcD_C)
4 TYR A 161
TYR A 160
ILE A 137
GLY A 183
None
1.06A 2du8J-4m0vA:
undetectable
2du8J-4m0vA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m87 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]


(Neisseria
meningitidis)
PF13561
(adh_short_C2)
4 TYR A 147
TYR A 157
ILE A 201
GLY A 191
NAD  A 301 ( 4.9A)
None
None
None
1.22A 2du8J-4m87A:
4.7
2du8J-4m87A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mmh HEPARINASE III
PROTEIN


(Pedobacter
heparinus)
PF07940
(Hepar_II_III)
PF16889
(Hepar_II_III_N)
4 TYR A 306
TYR A 322
ILE A 270
GLY A 307
None
1.16A 2du8J-4mmhA:
undetectable
2du8J-4mmhA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]


(Candidatus
Liberibacter
asiaticus)
PF13561
(adh_short_C2)
4 TYR A 146
TYR A 156
ILE A 200
GLY A 190
None
1.18A 2du8J-4nk5A:
4.2
2du8J-4nk5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oic BET V I
ALLERGEN-LIKE


(Oryza sativa)
PF10604
(Polyketide_cyc2)
4 TYR A  73
ILE A  63
ARG A  94
GLY A  68
None
1.10A 2du8J-4oicA:
undetectable
2du8J-4oicA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE


(Bacillus
subtilis)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 TYR A 287
TYR A 319
ILE A 305
GLY A 219
None
1.30A 2du8J-4rjkA:
undetectable
2du8J-4rjkA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr4 TYPE III
IODOTHYRONINE
DEIODINASE


(Mus musculus)
PF00837
(T4_deiodinase)
4 TYR A 262
ILE A 269
ARG A 275
GLY A 274
None
1.22A 2du8J-4tr4A:
2.5
2du8J-4tr4A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wz9 AGAP004809-PA

(Anopheles
gambiae)
PF01433
(Peptidase_M1)
PF11838
(ERAP1_C)
4 TYR A 740
TYR A 708
ILE A 731
GLY A 739
None
1.11A 2du8J-4wz9A:
undetectable
2du8J-4wz9A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xeu TRANSKETOLASE

(Pseudomonas
aeruginosa)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
4 TYR A 589
TYR A 622
ILE A 555
GLY A 539
None
1.24A 2du8J-4xeuA:
3.1
2du8J-4xeuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhj ENVELOPE
GLYCOPROTEIN H


(Human
alphaherpesvirus
3)
PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C)
4 TYR A 364
TYR A 365
ILE A 271
GLY A 248
None
1.03A 2du8J-4xhjA:
undetectable
2du8J-4xhjA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwl EXOGLUCANASE S

(Clostridium
cellulovorans)
PF02011
(Glyco_hydro_48)
4 TYR A 374
TYR A 267
ILE A 306
GLY A 372
None
1.32A 2du8J-4xwlA:
undetectable
2du8J-4xwlA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfl 1B2530 LIGHT CHAIN

(Homo sapiens)
no annotation 4 TYR L  91
TYR L  32
ARG L  96
GLY L  95
None
1.15A 2du8J-4yflL:
undetectable
2du8J-4yflL:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwj CHIMERA PROTEIN OF
HUMAN RHODOPSIN,
MOUSE S-ARRESTIN,
AND T4 ENDOLYSIN


(Homo sapiens;
Mus musculus;
Escherichia
virus T4)
PF00001
(7tm_1)
PF00339
(Arrestin_N)
PF00959
(Phage_lysozyme)
PF02752
(Arrestin_C)
PF10413
(Rhodopsin_N)
4 TYR A 192
TYR A 191
ILE A 189
GLY A 182
None
1.15A 2du8J-4zwjA:
undetectable
2du8J-4zwjA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cg0 BETA-GLUCOSIDASE

(Spodoptera
frugiperda)
PF00232
(Glyco_hydro_1)
4 TYR A 441
TYR A 483
ILE A 486
GLY A 440
None
1.32A 2du8J-5cg0A:
undetectable
2du8J-5cg0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fca ACID
SPHINGOMYELINASE-LIK
E PHOSPHODIESTERASE
3A


(Mus musculus)
PF00149
(Metallophos)
4 TYR A 337
TYR A 245
ILE A 202
GLY A 340
None
1.31A 2du8J-5fcaA:
undetectable
2du8J-5fcaA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fx8 LINOLEATE
11-LIPOXYGENASE


(Gaeumannomyces
avenae)
PF00305
(Lipoxygenase)
4 TYR A  83
TYR A 326
ILE A  92
GLY A  73
None
1.17A 2du8J-5fx8A:
undetectable
2du8J-5fx8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2h O-METHYLTRANSFERASE
FAMILY 2


(Planctopirus
limnophila)
PF00891
(Methyltransf_2)
PF16864
(Dimerisation2)
4 TYR A 327
TYR A 332
ILE A 296
GLY A 324
None
1.37A 2du8J-5i2hA:
3.1
2du8J-5i2hA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6s ENDOGLUCANASE

(Talaromyces
verruculosus)
PF00150
(Cellulase)
4 TYR A 209
TYR A 293
ILE A 292
GLY A 214
None
1.36A 2du8J-5i6sA:
undetectable
2du8J-5i6sA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iq6 RNA DEPENDENT RNA
POLYMERASE


(Dengue virus)
PF00972
(Flavi_NS5)
4 TYR A 299
TYR A 304
ILE A 591
ARG A 581
None
1.30A 2du8J-5iq6A:
undetectable
2du8J-5iq6A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuy MULTIDRUG EFFLUX
OUTER MEMBRANE
PROTEIN OPRN


(Pseudomonas
aeruginosa)
PF02321
(OEP)
4 TYR A 369
TYR A  25
ILE A 255
GLY A 431
None
1.07A 2du8J-5iuyA:
undetectable
2du8J-5iuyA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jsi BACTERIORHODOPSIN

(Candidatus
Actinomarina
minuta)
PF01036
(Bac_rhodopsin)
4 TYR A  70
ILE A 109
ARG A 188
GLY A 175
None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
1.22A 2du8J-5jsiA:
undetectable
2du8J-5jsiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jt8 BLO T 1 ALLERGEN

(Blomia
tropicalis)
PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29)
4 TYR A 242
TYR A  52
ILE A  47
GLY A 253
NO3  A 405 (-4.5A)
None
None
None
1.36A 2du8J-5jt8A:
undetectable
2du8J-5jt8A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koi ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]


(Brucella
abortus)
PF13561
(adh_short_C2)
4 TYR A 147
TYR A 157
ILE A 201
GLY A 191
NAD  A 300 ( 4.8A)
None
None
None
1.15A 2du8J-5koiA:
5.4
2du8J-5koiA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koj NITROGENASE PROTEIN
ALPHA CHAIN


(Gluconacetobacter
diazotrophicus)
PF00148
(Oxidored_nitro)
4 TYR A 370
TYR A 417
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.21A 2du8J-5kojA:
2.8
2du8J-5kojA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koj NITROGENASE PROTEIN
ALPHA CHAIN


(Gluconacetobacter
diazotrophicus)
PF00148
(Oxidored_nitro)
4 TYR A 395
TYR A 403
ILE A 416
GLY A 372
None
None
None
ICS  A 502 (-3.5A)
1.28A 2du8J-5kojA:
2.8
2du8J-5kojA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lvy ADHESIN PROTEIN

(Escherichia
coli)
no annotation 4 TYR A 115
TYR A 120
ILE A 159
GLY A 114
None
1.32A 2du8J-5lvyA:
undetectable
2du8J-5lvyA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngh ODORANT BINDING
PROTEIN 3


(Ailuropoda
melanoleuca)
no annotation 4 TYR A  19
ILE A  46
ARG A 163
GLY A 164
None
1.27A 2du8J-5nghA:
undetectable
2du8J-5nghA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5suo EXTRACELLULAR
SOLUTE-BINDING
PROTEIN


(Streptococcus
pneumoniae)
PF12010
(DUF3502)
4 TYR A 115
TYR A 106
ILE A 107
GLY A 113
None
1.10A 2du8J-5suoA:
undetectable
2du8J-5suoA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5van BETA-KLOTHO

(Homo sapiens)
no annotation 4 TYR A 457
TYR A 499
ILE A 502
GLY A 456
None
1.30A 2du8J-5vanA:
undetectable
2du8J-5vanA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wi9 -

(-)
no annotation 4 TYR A 457
TYR A 499
ILE A 502
GLY A 456
None
1.31A 2du8J-5wi9A:
undetectable
2du8J-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7


(Homo sapiens)
no annotation 4 TYR C  84
TYR C  94
ILE C  34
GLY C  77
None
1.30A 2du8J-5wlzC:
undetectable
2du8J-5wlzC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xd7 3,6-ANHYDRO-ALPHA-L-
GALACTONATE
CYCLOISOMERASE


(Vibrio sp. EJY3)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 TYR A  52
TYR A  50
ILE A 110
GLY A 301
None
1.11A 2du8J-5xd7A:
undetectable
2du8J-5xd7A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsx CHITINASE

(Thermococcus
chitonophagus)
no annotation 4 TYR A 431
ILE A 471
ARG A 425
GLY A 426
None
1.14A 2du8J-5xsxA:
undetectable
2du8J-5xsxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yj6 DOCKERIN TYPE I
REPEAT-CONTAINING
PROTEIN


(Ruminiclostridium
thermocellum)
no annotation 4 TYR A 410
TYR A 302
ILE A 342
GLY A 408
None
1.29A 2du8J-5yj6A:
undetectable
2du8J-5yj6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cr0 (S)-6-HYDROXYNICOTIN
E OXIDASE


(Shinella sp.
HZN7)
no annotation 4 TYR A 367
ILE A  56
ARG A  37
GLY A  42
None
None
FAD  A 507 (-4.4A)
FAD  A 507 (-3.1A)
1.32A 2du8J-6cr0A:
12.4
2du8J-6cr0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eo5 PPBBE-LIKE 1 D396N

(Physcomitrella
patens)
no annotation 4 TYR A 472
TYR A 471
ILE A 462
GLY A 229
None
1.36A 2du8J-6eo5A:
undetectable
2du8J-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f34 AMINO ACID
TRANSPORTER


(Geobacillus
kaustophilus)
no annotation 4 TYR A  95
TYR A  79
ILE A 257
GLY A  90
None
1.21A 2du8J-6f34A:
undetectable
2du8J-6f34A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARE


(Acetobacterium
woodii)
no annotation 4 TYR A 155
TYR A 129
ILE A 107
GLY A 153
None
1.38A 2du8J-6fahA:
3.0
2du8J-6fahA:
undetectable