SIMILAR PATTERNS OF AMINO ACIDS FOR 2DU8_A_BEZA352

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1akm ORNITHINE
TRANSCARBAMYLASE


(Escherichia
coli)
PF00185
(OTCace)
PF02729
(OTCace_N)
4 LEU A 116
TYR A 105
ILE A  50
GLY A  84
None
0.86A 2du8A-1akmA:
4.3
2du8A-1akmA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6s O-ACETYLSERINE
SULFHYDRYLASE


(Salmonella
enterica)
PF00291
(PALP)
4 LEU A  64
TYR A  85
ILE A  49
GLY A  56
None
0.90A 2du8A-1d6sA:
1.3
2du8A-1d6sA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fhq PROTEIN KINASE SPK1

(Saccharomyces
cerevisiae)
PF00498
(FHA)
4 LEU A 672
TYR A 649
ILE A 625
GLY A 691
None
0.90A 2du8A-1fhqA:
undetectable
2du8A-1fhqA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fn9 OUTER-CAPSID PROTEIN
SIGMA 3


(Reovirus sp.)
PF00979
(Reovirus_cap)
4 LEU A 228
TYR A 225
ILE A 180
GLY A 350
None
0.77A 2du8A-1fn9A:
undetectable
2du8A-1fn9A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwi CYTOCHROME P450
154C1


(Streptomyces
coelicolor)
PF00067
(p450)
4 LEU A 321
TYR A 318
ILE A 346
ARG A 295
None
HEM  A1414 (-3.9A)
None
HEM  A1414 (-2.9A)
0.86A 2du8A-1gwiA:
undetectable
2du8A-1gwiA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2d ATP SULFURYLASE

(Penicillium
chrysogenum)
PF01583
(APS_kinase)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2)
4 LEU A 323
TYR A 319
ILE A 274
GLY A  76
None
0.92A 2du8A-1i2dA:
2.0
2du8A-1i2dA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iuq GLYCEROL-3-PHOSPHATE
ACYLTRANSFERASE


(Cucurbita
moschata)
PF01553
(Acyltransferase)
PF14829
(GPAT_N)
4 LEU A  41
TYR A  45
ILE A 298
GLY A  99
None
0.85A 2du8A-1iuqA:
undetectable
2du8A-1iuqA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l3w EP-CADHERIN

(Xenopus laevis)
PF00028
(Cadherin)
4 LEU A 189
TYR A 187
ILE A 209
GLY A 176
None
NAG  A 801 (-4.2A)
None
None
0.87A 2du8A-1l3wA:
undetectable
2du8A-1l3wA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n61 CARBON MONOXIDE
DEHYDROGENASE MEDIUM
CHAIN


(Oligotropha
carboxidovorans)
PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C)
4 LEU C 128
ILE C  94
ARG C 285
GLY C 180
None
0.94A 2du8A-1n61C:
undetectable
2du8A-1n61C:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obh LEUCYL-TRNA
SYNTHETASE


(Thermus
thermophilus)
PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2)
PF14795
(Leucyl-specific)
4 LEU A 547
ILE A 196
ARG A 418
GLY A 225
None
0.92A 2du8A-1obhA:
undetectable
2du8A-1obhA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p8r ARGINASE 1

(Rattus
norvegicus)
PF00491
(Arginase)
4 LEU A 179
TYR A 176
ILE A 190
GLY A 142
None
None
None
S2C  A 551 ( 3.9A)
0.86A 2du8A-1p8rA:
3.1
2du8A-1p8rA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus)
PF00028
(Cadherin)
4 LEU A 189
TYR A 187
ILE A 209
GLY A 176
None
NAG  A 801 (-4.2A)
None
None
0.77A 2du8A-1q5aA:
undetectable
2du8A-1q5aA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5d P450 EPOXIDASE

(Sorangium
cellulosum)
PF00067
(p450)
4 LEU A 295
TYR A 358
ILE A 300
GLY A 367
HEM  A 440 ( 4.8A)
HEM  A 440 (-4.4A)
None
HEM  A 440 (-3.6A)
0.89A 2du8A-1q5dA:
undetectable
2du8A-1q5dA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sgq STREPTOMYCES GRISEUS
PROTEINASE B


(Streptomyces
griseus)
PF00089
(Trypsin)
4 LEU E  85
TYR E 108
ILE E 113
GLY E  18
None
0.92A 2du8A-1sgqE:
undetectable
2du8A-1sgqE:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0l PROBABLE GTPASE ENGC

(Thermotoga
maritima)
PF03193
(RsgA_GTPase)
PF16745
(RsgA_N)
4 LEU A 210
TYR A 218
ILE A 165
GLY A   7
None
0.89A 2du8A-1u0lA:
undetectable
2du8A-1u0lA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE


(Saccharomyces
cerevisiae)
PF06052
(3-HAO)
4 LEU A  29
ILE A   9
ARG A 101
GLY A  40
None
0.89A 2du8A-1zvfA:
undetectable
2du8A-1zvfA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aqw PUTATIVE
OROTIDINE-MONOPHOSPH
ATE-DECARBOXYLASE


(Plasmodium
yoelii)
PF00215
(OMPdecase)
4 LEU A  18
TYR A 312
ILE A 299
GLY A 268
None
None
None
SO4  A2002 ( 4.9A)
0.90A 2du8A-2aqwA:
undetectable
2du8A-2aqwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bht CYSTEINE SYNTHASE B

(Escherichia
coli)
PF00291
(PALP)
4 LEU A  64
TYR A  85
ILE A  49
GLY A  56
None
0.94A 2du8A-2bhtA:
undetectable
2du8A-2bhtA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfb GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE


(Synechococcus
elongatus)
PF00202
(Aminotran_3)
4 LEU A 378
TYR A  41
ILE A 376
GLY A 320
None
0.86A 2du8A-2cfbA:
undetectable
2du8A-2cfbA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2epk N-ACETYL-BETA-D-GLUC
OSAMINIDASE


(Streptococcus
gordonii)
PF00728
(Glyco_hydro_20)
4 LEU X  65
TYR X  48
ILE X  27
GLY X  72
None
0.95A 2du8A-2epkX:
2.2
2du8A-2epkX:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5u VIRION PROTEIN UL25

(Human
alphaherpesvirus
1)
PF01499
(Herpes_UL25)
4 LEU A 443
TYR A 447
ILE A 140
GLY A 466
None
0.67A 2du8A-2f5uA:
undetectable
2du8A-2f5uA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fcd MYOSIN LIGHT CHAIN 1

(Saccharomyces
cerevisiae)
no annotation 4 LEU A  31
TYR A  36
ILE A  34
GLY A  66
None
0.91A 2du8A-2fcdA:
undetectable
2du8A-2fcdA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fwr DNA REPAIR PROTEIN
RAD25


(Archaeoglobus
fulgidus)
PF04851
(ResIII)
PF16203
(ERCC3_RAD25_C)
4 LEU A 271
TYR A 279
ILE A 329
GLY A 423
None
0.95A 2du8A-2fwrA:
undetectable
2du8A-2fwrA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ghs AGR_C_1268P

(Agrobacterium
fabrum)
PF08450
(SGL)
4 LEU A  99
TYR A 312
ILE A 137
GLY A 133
None
0.88A 2du8A-2ghsA:
undetectable
2du8A-2ghsA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2guu ODCASE

(Plasmodium
vivax)
PF00215
(OMPdecase)
4 LEU A  36
TYR A 340
ILE A 327
GLY A 296
None
0.86A 2du8A-2guuA:
undetectable
2du8A-2guuA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2htb PUTATIVE ENZYME
RELATED TO ALDOSE
1-EPIMERASE


(Salmonella
enterica)
PF01263
(Aldose_epim)
4 LEU A 196
TYR A 211
ILE A 200
GLY A 241
None
0.91A 2du8A-2htbA:
undetectable
2du8A-2htbA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxg L-ARABINOSE
ISOMERASE


(Escherichia
coli)
PF02610
(Arabinose_Isome)
PF11762
(Arabinose_Iso_C)
4 LEU A 396
TYR A 403
ILE A 471
GLY A 203
None
0.92A 2du8A-2hxgA:
undetectable
2du8A-2hxgA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i34 ACID PHOSPHATASE

(Bacillus
anthracis)
PF03767
(Acid_phosphat_B)
4 LEU A  66
TYR A 122
ILE A 151
GLY A 142
WO4  A 401 (-4.1A)
None
None
None
0.67A 2du8A-2i34A:
undetectable
2du8A-2i34A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iht CARBOXYETHYLARGININE
SYNTHASE


(Streptomyces
clavuligerus)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 LEU A 498
TYR A 499
ILE A 502
GLY A 270
None
0.71A 2du8A-2ihtA:
undetectable
2du8A-2ihtA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j42 C2 TOXIN
COMPONENT-II


(Clostridium
botulinum)
PF03495
(Binary_toxB)
PF07691
(PA14)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3)
4 LEU A  92
TYR A 115
ILE A  71
GLY A  77
None
0.87A 2du8A-2j42A:
undetectable
2du8A-2j42A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jkd PRE-MRNA LEAKAGE
PROTEIN 1


(Saccharomyces
cerevisiae)
PF00498
(FHA)
4 LEU A  80
TYR A  96
ILE A  82
GLY A 107
None
0.94A 2du8A-2jkdA:
undetectable
2du8A-2jkdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq5 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE


(Streptococcus
mutans)
PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1)
4 LEU A 311
ILE A 313
ARG A 360
GLY A 359
None
0.74A 2du8A-2nq5A:
undetectable
2du8A-2nq5A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1f URIDINE
5'-MONOPHOSPHATE
SYNTHASE


(Homo sapiens)
PF00215
(OMPdecase)
4 LEU A  65
TYR A 277
ILE A 264
GLY A 229
None
0.83A 2du8A-2p1fA:
undetectable
2du8A-2p1fA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qcm URIDINE
5'-MONOPHOSPHATE
SYNTHASE (UMP
SYNTHASE)


(Homo sapiens)
PF00215
(OMPdecase)
4 LEU A 254
TYR A 466
ILE A 453
GLY A 418
None
None
None
JW5  A 482 ( 4.9A)
0.81A 2du8A-2qcmA:
undetectable
2du8A-2qcmA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qga ADENYLOSUCCINATE
LYASE


(Plasmodium
vivax)
PF00206
(Lyase_1)
PF08328
(ASL_C)
4 LEU B 282
TYR B 276
ILE B 273
GLY B 178
None
0.86A 2du8A-2qgaB:
undetectable
2du8A-2qgaB:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt3 N-ISOPROPYLAMMELIDE
ISOPROPYL
AMIDOHYDROLASE


(Pseudomonas sp.
ADP)
PF01979
(Amidohydro_1)
4 LEU A 232
TYR A 216
ILE A 214
GLY A 198
None
0.91A 2du8A-2qt3A:
undetectable
2du8A-2qt3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qz6 BETA-LACTAMASE

(Pseudomonas
fluorescens)
PF00144
(Beta-lactamase)
4 LEU A  96
TYR A 135
ILE A 132
GLY A 159
None
0.74A 2du8A-2qz6A:
undetectable
2du8A-2qz6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ri0 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE


(Streptococcus
mutans)
PF01182
(Glucosamine_iso)
4 LEU A  42
TYR A  43
ILE A  46
GLY A  32
None
0.93A 2du8A-2ri0A:
undetectable
2du8A-2ri0A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhl N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE


(Bacillus
subtilis)
PF01979
(Amidohydro_1)
4 LEU A  87
TYR A  68
ILE A  64
GLY A 287
None
0.93A 2du8A-2vhlA:
undetectable
2du8A-2vhlA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2za1 OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE


(Plasmodium
falciparum)
PF00215
(OMPdecase)
4 LEU A  18
TYR A 309
ILE A 296
GLY A 265
None
0.92A 2du8A-2za1A:
undetectable
2du8A-2za1A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ail 303AA LONG
HYPOTHETICAL
ESTERASE


(Sulfurisphaera
tokodaii)
PF07859
(Abhydrolase_3)
4 LEU A  92
TYR A  75
ILE A 289
GLY A 147
None
0.93A 2du8A-3ailA:
2.1
2du8A-3ailA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3chi P-AMINOBENZOATE
N-OXYGENASE


(Streptomyces
thioluteus)
PF11583
(AurF)
5 LEU A 206
TYR A  93
TYR A  61
ILE A  65
ARG A  96
None
1.30A 2du8A-3chiA:
undetectable
2du8A-3chiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cue TRANSPORT PROTEIN
PARTICLE 31 KDA
SUBUNIT
TRANSPORT PROTEIN
PARTICLE 22 KDA
SUBUNIT


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF04051
(TRAPP)
PF04051
(TRAPP)
4 LEU B  65
TYR D  34
ILE D  37
GLY D 146
None
0.91A 2du8A-3cueB:
undetectable
2du8A-3cueB:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmk DOWN SYNDROME CELL
ADHESION MOLECULE
(DSCAM) ISOFORM
1.30.30, N-TERMINAL
EIGHT IG DOMAINS


(Drosophila
melanogaster)
PF07679
(I-set)
PF13927
(Ig_3)
4 LEU A 457
TYR A 441
ILE A 435
GLY A 468
None
0.88A 2du8A-3dmkA:
undetectable
2du8A-3dmkA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e59 PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCA


(Pseudomonas
aeruginosa)
PF05141
(DIT1_PvcA)
4 LEU A  94
ILE A 108
ARG A  22
GLY A 265
None
0.87A 2du8A-3e59A:
undetectable
2du8A-3e59A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3els PRE-MRNA LEAKAGE
PROTEIN 1


(Saccharomyces
cerevisiae)
PF00498
(FHA)
4 LEU A  80
TYR A  96
ILE A  82
GLY A 107
None
0.90A 2du8A-3elsA:
undetectable
2du8A-3elsA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fk5 3-OXOACYL-SYNTHASE
III


(Xanthomonas
oryzae)
PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III)
4 LEU A 305
ILE A 320
ARG A 313
GLY A 312
None
0.90A 2du8A-3fk5A:
undetectable
2du8A-3fk5A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7k AGMATINE DEIMINASE

(Arabidopsis
thaliana)
PF04371
(PAD_porph)
4 LEU A 203
ILE A 118
ARG A  93
GLY A 164
None
None
None
AGT  A 366 ( 3.5A)
0.82A 2du8A-3h7kA:
undetectable
2du8A-3h7kA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kiz PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE


(Cytophaga
hutchinsonii)
PF02769
(AIRS_C)
4 LEU A 380
TYR A 392
ILE A 382
GLY A 291
None
0.88A 2du8A-3kizA:
undetectable
2du8A-3kizA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvt POTASSIUM CHANNEL
PROTEIN SHAW


(Aplysia
californica)
PF02214
(BTB_2)
4 LEU A  74
TYR A  76
ILE A  65
GLY A  82
None
0.83A 2du8A-3kvtA:
undetectable
2du8A-3kvtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE


(Parabacteroides
distasonis)
PF02769
(AIRS_C)
4 LEU A 377
TYR A 388
ILE A 379
GLY A 290
None
0.90A 2du8A-3mdoA:
undetectable
2du8A-3mdoA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr1 PUTATIVE
D-GALACTONATE
DEHYDRATASE


(Ralstonia
pickettii)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 LEU A 223
TYR A 220
ILE A 231
GLY A 186
None
0.95A 2du8A-3rr1A:
undetectable
2du8A-3rr1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE


(Streptococcus
mutans)
PF01070
(FMN_dh)
4 LEU A  27
TYR A 319
ILE A  25
GLY A 266
None
0.75A 2du8A-3sr7A:
undetectable
2du8A-3sr7A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpy FHA
DOMAIN-CONTAINING
PROTEIN DDL


(Arabidopsis
thaliana)
PF00498
(FHA)
4 LEU A  19
TYR A 126
ILE A 117
GLY A  43
None
0.94A 2du8A-3vpyA:
undetectable
2du8A-3vpyA:
17.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w4k D-AMINO-ACID OXIDASE

(Homo sapiens)
PF01266
(DAO)
5 LEU A 215
TYR A 228
ILE A 230
ARG A 283
GLY A 313
3LD  A 402 (-4.1A)
3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
0.35A 2du8A-3w4kA:
55.2
2du8A-3w4kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w4k D-AMINO-ACID OXIDASE

(Homo sapiens)
PF01266
(DAO)
4 TYR A 224
TYR A 228
ARG A 283
GLY A 313
3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
0.74A 2du8A-3w4kA:
55.2
2du8A-3w4kA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrt BETA-LACTAMASE

(Chromohalobacter
sp. 560)
PF00144
(Beta-lactamase)
4 LEU A 120
TYR A 151
ILE A 293
GLY A  64
None
0.78A 2du8A-3wrtA:
undetectable
2du8A-3wrtA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1


(Rattus
norvegicus)
PF01150
(GDA1_CD39)
4 LEU A 105
TYR A 104
ILE A 101
GLY A  56
None
0.93A 2du8A-3zx2A:
undetectable
2du8A-3zx2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ap3 STEROID
MONOOXYGENASE


(Rhodococcus
rhodochrous)
PF00743
(FMO-like)
4 LEU A 105
TYR A  79
TYR A 104
ILE A 101
None
0.93A 2du8A-4ap3A:
7.0
2du8A-4ap3A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT


(Pseudonaja
textilis)
PF00754
(F5_F8_type_C)
PF07732
(Cu-oxidase_3)
4 LEU V 163
TYR V 143
ILE V 165
GLY V1056
None
0.91A 2du8A-4bxsV:
undetectable
2du8A-4bxsV:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23


(Arabidopsis
thaliana)
PF00069
(Pkinase)
4 LEU A 240
TYR A 241
ILE A 244
GLY A 193
None
0.77A 2du8A-4cztA:
undetectable
2du8A-4cztA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A


(Cellvibrio
japonicus)
PF02449
(Glyco_hydro_42)
4 LEU A  51
TYR A  58
ILE A 198
GLY A  62
None
0.87A 2du8A-4d1iA:
undetectable
2du8A-4d1iA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djm DRAB

(Escherichia
coli)
PF00345
(PapD_N)
PF02753
(PapD_C)
4 LEU A 145
TYR A  33
ILE A  88
GLY A  92
None
0.92A 2du8A-4djmA:
undetectable
2du8A-4djmA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dnh UNCHARACTERIZED
PROTEIN


(Sinorhizobium
meliloti)
PF06187
(DUF993)
4 LEU A 180
TYR A 176
ILE A 189
GLY A 121
None
0.93A 2du8A-4dnhA:
undetectable
2du8A-4dnhA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR


(Escherichia
coli)
PF00563
(EAL)
4 LEU A 121
TYR A 118
ILE A 114
GLY A 129
None
0.93A 2du8A-4es4A:
undetectable
2du8A-4es4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens)
PF01433
(Peptidase_M1)
PF11838
(ERAP1_C)
4 LEU A 346
TYR A 194
ILE A 283
GLY A 192
None
0.95A 2du8A-4fysA:
undetectable
2du8A-4fysA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g0b HYDROXYCINNAMOYL-COA
SHIKIMATE/QUINATE
HYDROXYCINNAMOYLTRAN
SFERASE


(Coffea
canephora)
PF02458
(Transferase)
5 LEU A 147
TYR A  42
TYR A  40
ILE A 165
GLY A 385
None
1.47A 2du8A-4g0bA:
undetectable
2du8A-4g0bA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iu9 NITRITE EXTRUSION
PROTEIN 2


(Escherichia
coli)
no annotation 4 LEU B 404
ILE B 407
ARG B 303
GLY B 364
None
0.84A 2du8A-4iu9B:
undetectable
2du8A-4iu9B:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1


(Arabidopsis
thaliana)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 LEU A 670
TYR A 659
ILE A 675
GLY A 565
None
0.92A 2du8A-4j0mA:
undetectable
2du8A-4j0mA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4luj OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE


(Methanocaldococcus
jannaschii)
PF00215
(OMPdecase)
4 LEU A  24
TYR A 227
ILE A 214
GLY A 187
None
0.88A 2du8A-4lujA:
undetectable
2du8A-4lujA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mjz OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE


(Toxoplasma
gondii)
PF00215
(OMPdecase)
4 LEU A  40
TYR A 302
ILE A 289
GLY A 258
None
0.85A 2du8A-4mjzA:
undetectable
2du8A-4mjzA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6c UNCHARACTERIZED
PROTEIN


(Streptococcus
pneumoniae)
PF08020
(DUF1706)
4 LEU A 106
TYR A  21
ILE A 110
GLY A 158
None
0.92A 2du8A-4n6cA:
undetectable
2du8A-4n6cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o8s PUTATIVE

(Helicobacter
pylori)
PF08843
(AbiEii)
4 LEU A 112
TYR A  95
ILE A 114
GLY A  68
None
0.79A 2du8A-4o8sA:
undetectable
2du8A-4o8sA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ok0 PUTATIVE

(Helicobacter
pylori)
PF08843
(AbiEii)
4 LEU A 112
TYR A  95
ILE A 114
GLY A  68
None
0.74A 2du8A-4ok0A:
undetectable
2du8A-4ok0A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgi UNCHARACTERIZED
PROTEIN


(Yersinia pestis)
PF13619
(KTSC)
4 LEU A  23
TYR A  35
ILE A  25
GLY A  58
None
0.81A 2du8A-4rgiA:
undetectable
2du8A-4rgiA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4weo PUTATIVE
ACETOIN(DIACETYL)
REDUCTASE


(Burkholderia
cenocepacia)
PF00106
(adh_short)
4 LEU A 153
TYR A 156
ILE A  95
GLY A 187
None
0.81A 2du8A-4weoA:
6.2
2du8A-4weoA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xeu TRANSKETOLASE

(Pseudomonas
aeruginosa)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
5 LEU A 601
TYR A 589
TYR A 622
ILE A 555
GLY A 539
None
1.20A 2du8A-4xeuA:
undetectable
2du8A-4xeuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhj ENVELOPE
GLYCOPROTEIN H


(Human
alphaherpesvirus
3)
PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C)
4 TYR A 364
TYR A 365
ILE A 271
GLY A 248
None
0.95A 2du8A-4xhjA:
undetectable
2du8A-4xhjA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zu9 ELONGATION FACTOR
SELB


(Aquifex
aeolicus)
PF00009
(GTP_EFTU)
PF09107
(SelB-wing_3)
4 LEU A 451
TYR A 457
ILE A 417
GLY A 430
None
0.93A 2du8A-4zu9A:
undetectable
2du8A-4zu9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah0 LIPASE

(Pelosinus
fermentans)
no annotation 4 LEU A 367
TYR A 277
ILE A 174
GLY A 390
None
0.87A 2du8A-5ah0A:
undetectable
2du8A-5ah0A:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b37 TRYPTOPHAN
DEHYDROGENASE


(Nostoc
punctiforme)
PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N)
4 LEU A 270
TYR A 277
ILE A 252
GLY A 237
None
0.69A 2du8A-5b37A:
3.8
2du8A-5b37A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es6 LINEAR GRAMICIDIN
SYNTHASE SUBUNIT A


(Brevibacillus
parabrevis)
PF00501
(AMP-binding)
PF00551
(Formyl_trans_N)
4 LEU A 400
TYR A 439
ILE A 460
GLY A 482
None
0.95A 2du8A-5es6A:
undetectable
2du8A-5es6A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es9 LINEAR GRAMICIDIN
SYNTHETASE SUBUNIT A


(Brevibacillus
parabrevis)
PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00551
(Formyl_trans_N)
PF13193
(AMP-binding_C)
4 LEU A 400
TYR A 439
ILE A 460
GLY A 482
None
0.91A 2du8A-5es9A:
undetectable
2du8A-5es9A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjw VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1


(Oryctolagus
cuniculus)
PF00092
(VWA)
PF08399
(VWA_N)
PF08473
(VGCC_alpha2)
4 LEU F 889
TYR F 895
ILE F1019
GLY F 859
None
0.94A 2du8A-5gjwF:
undetectable
2du8A-5gjwF:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihe DNA POLYMERASE II
SMALL SUBUNIT


(Pyrococcus
abyssi)
PF00149
(Metallophos)
4 LEU A 431
TYR A 428
ILE A 471
GLY A 449
None
0.89A 2du8A-5iheA:
undetectable
2du8A-5iheA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnf LINEAR GRAMICIDIN
SYNTHASE SUBUNIT A


(Brevibacillus
parabrevis)
no annotation 4 LEU C 400
TYR C 439
ILE C 460
GLY C 482
None
FMT  C 604 (-4.9A)
None
None
0.93A 2du8A-5jnfC:
undetectable
2du8A-5jnfC:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnm MANNITOL-1-PHOSPHATE
5-DEHYDROGENASE


(Staphylococcus
aureus)
no annotation 4 LEU A  40
TYR A  46
ILE A  36
GLY A  14
None
0.83A 2du8A-5jnmA:
4.3
2du8A-5jnmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jsb INDUCED MYELOID
LEUKEMIA CELL
DIFFERENTIATION
PROTEIN MCL-1


(Homo sapiens)
PF00452
(Bcl-2)
4 LEU A 186
TYR A 185
ILE A 294
GLY A 217
None
0.87A 2du8A-5jsbA:
undetectable
2du8A-5jsbA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kjv HYDROXYCINNAMOYL
TRANSFERASE


(Plectranthus
scutellarioides)
PF02458
(Transferase)
5 LEU A 147
TYR A  42
TYR A  40
ILE A 165
GLY A 378
None
1.49A 2du8A-5kjvA:
undetectable
2du8A-5kjvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2h CENTYRIN

(synthetic
construct)
PF00041
(fn3)
4 LEU A  20
TYR A  57
ILE A  34
GLY A  61
None
0.95A 2du8A-5l2hA:
undetectable
2du8A-5l2hA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l8s AMINO ACYL PEPTIDASE

(Sporosarcina
psychrophila)
PF00326
(Peptidase_S9)
4 LEU A 272
TYR A 261
ILE A 305
GLY A 301
None
0.95A 2du8A-5l8sA:
undetectable
2du8A-5l8sA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mev INDUCED MYELOID
LEUKEMIA CELL
DIFFERENTIATION
PROTEIN MCL-1
HOMOLOG,INDUCED
MYELOID LEUKEMIA
CELL DIFFERENTIATION
PROTEIN MCL-1


(Homo sapiens;
Mus musculus)
PF00452
(Bcl-2)
4 LEU A 186
TYR A 185
ILE A 294
GLY A 217
None
0.90A 2du8A-5mevA:
undetectable
2du8A-5mevA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B


(Acinetobacter
calcoaceticus)
no annotation 4 LEU A 149
TYR A  95
ILE A 151
GLY A 206
None
0.91A 2du8A-5minA:
undetectable
2du8A-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1


(Homo sapiens)
PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9)
4 LEU A1615
TYR A1618
ILE A1557
GLY A1642
None
0.92A 2du8A-5nugA:
undetectable
2du8A-5nugA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ool 39S RIBOSOMAL
PROTEIN L37,
MITOCHONDRIAL


(Homo sapiens)
PF07147
(PDCD9)
4 LEU 5 382
TYR 5 383
ILE 5 158
ARG 5 173
None
None
None
A  A2395 ( 3.0A)
0.95A 2du8A-5ool5:
undetectable
2du8A-5ool5:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr1 CHLORIDE CHANNEL
PROTEIN


(Bos taurus)
PF00654
(Voltage_CLC)
4 LEU A 139
TYR A 138
ILE A 129
GLY A 204
None
0.94A 2du8A-5tr1A:
undetectable
2du8A-5tr1A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L


(Drosophila
melanogaster)
PF00023
(Ank)
PF00520
(Ion_trans)
PF12796
(Ank_2)
PF13637
(Ank_4)
4 LEU A1016
TYR A1011
ILE A1007
GLY A 971
None
0.91A 2du8A-5vkqA:
undetectable
2du8A-5vkqA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsq NUCLEOPROTEIN

(Marburg
marburgvirus)
PF05505
(Ebola_NP)
4 LEU A  96
TYR A  93
ILE A  87
GLY A  38
None
0.93A 2du8A-5xsqA:
undetectable
2du8A-5xsqA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtc ACYL CARRIER
PROTEIN,
MITOCHONDRIAL


(Homo sapiens)
PF00550
(PP-binding)
4 LEU X  87
TYR X  90
ILE X 118
GLY X 109
None
0.95A 2du8A-5xtcX:
undetectable
2du8A-5xtcX:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6any BM4233, ISOFORM B

(Brugia malayi)
no annotation 4 LEU A 176
TYR A 100
ILE A 166
GLY A 120
None
0.67A 2du8A-6anyA:
undetectable
2du8A-6anyA:
undetectable