SIMILAR PATTERNS OF AMINO ACIDS FOR 2DU8_A_BEZA352
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1akm | ORNITHINETRANSCARBAMYLASE (Escherichiacoli) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | LEU A 116TYR A 105ILE A 50GLY A 84 | None | 0.86A | 2du8A-1akmA:4.3 | 2du8A-1akmA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6s | O-ACETYLSERINESULFHYDRYLASE (Salmonellaenterica) |
PF00291(PALP) | 4 | LEU A 64TYR A 85ILE A 49GLY A 56 | None | 0.90A | 2du8A-1d6sA:1.3 | 2du8A-1d6sA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhq | PROTEIN KINASE SPK1 (Saccharomycescerevisiae) |
PF00498(FHA) | 4 | LEU A 672TYR A 649ILE A 625GLY A 691 | None | 0.90A | 2du8A-1fhqA:undetectable | 2du8A-1fhqA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fn9 | OUTER-CAPSID PROTEINSIGMA 3 (Reovirus sp.) |
PF00979(Reovirus_cap) | 4 | LEU A 228TYR A 225ILE A 180GLY A 350 | None | 0.77A | 2du8A-1fn9A:undetectable | 2du8A-1fn9A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gwi | CYTOCHROME P450154C1 (Streptomycescoelicolor) |
PF00067(p450) | 4 | LEU A 321TYR A 318ILE A 346ARG A 295 | NoneHEM A1414 (-3.9A)NoneHEM A1414 (-2.9A) | 0.86A | 2du8A-1gwiA:undetectable | 2du8A-1gwiA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2d | ATP SULFURYLASE (Penicilliumchrysogenum) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 4 | LEU A 323TYR A 319ILE A 274GLY A 76 | None | 0.92A | 2du8A-1i2dA:2.0 | 2du8A-1i2dA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iuq | GLYCEROL-3-PHOSPHATEACYLTRANSFERASE (Cucurbitamoschata) |
PF01553(Acyltransferase)PF14829(GPAT_N) | 4 | LEU A 41TYR A 45ILE A 298GLY A 99 | None | 0.85A | 2du8A-1iuqA:undetectable | 2du8A-1iuqA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l3w | EP-CADHERIN (Xenopus laevis) |
PF00028(Cadherin) | 4 | LEU A 189TYR A 187ILE A 209GLY A 176 | NoneNAG A 801 (-4.2A)NoneNone | 0.87A | 2du8A-1l3wA:undetectable | 2du8A-1l3wA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n61 | CARBON MONOXIDEDEHYDROGENASE MEDIUMCHAIN (Oligotrophacarboxidovorans) |
PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 4 | LEU C 128ILE C 94ARG C 285GLY C 180 | None | 0.94A | 2du8A-1n61C:undetectable | 2du8A-1n61C:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1obh | LEUCYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00133(tRNA-synt_1)PF08264(Anticodon_1)PF13603(tRNA-synt_1_2)PF14795(Leucyl-specific) | 4 | LEU A 547ILE A 196ARG A 418GLY A 225 | None | 0.92A | 2du8A-1obhA:undetectable | 2du8A-1obhA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p8r | ARGINASE 1 (Rattusnorvegicus) |
PF00491(Arginase) | 4 | LEU A 179TYR A 176ILE A 190GLY A 142 | NoneNoneNoneS2C A 551 ( 3.9A) | 0.86A | 2du8A-1p8rA:3.1 | 2du8A-1p8rA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5a | EP-CADHERIN (Mus musculus) |
PF00028(Cadherin) | 4 | LEU A 189TYR A 187ILE A 209GLY A 176 | NoneNAG A 801 (-4.2A)NoneNone | 0.77A | 2du8A-1q5aA:undetectable | 2du8A-1q5aA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5d | P450 EPOXIDASE (Sorangiumcellulosum) |
PF00067(p450) | 4 | LEU A 295TYR A 358ILE A 300GLY A 367 | HEM A 440 ( 4.8A)HEM A 440 (-4.4A)NoneHEM A 440 (-3.6A) | 0.89A | 2du8A-1q5dA:undetectable | 2du8A-1q5dA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sgq | STREPTOMYCES GRISEUSPROTEINASE B (Streptomycesgriseus) |
PF00089(Trypsin) | 4 | LEU E 85TYR E 108ILE E 113GLY E 18 | None | 0.92A | 2du8A-1sgqE:undetectable | 2du8A-1sgqE:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u0l | PROBABLE GTPASE ENGC (Thermotogamaritima) |
PF03193(RsgA_GTPase)PF16745(RsgA_N) | 4 | LEU A 210TYR A 218ILE A 165GLY A 7 | None | 0.89A | 2du8A-1u0lA:undetectable | 2du8A-1u0lA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zvf | 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE (Saccharomycescerevisiae) |
PF06052(3-HAO) | 4 | LEU A 29ILE A 9ARG A 101GLY A 40 | None | 0.89A | 2du8A-1zvfA:undetectable | 2du8A-1zvfA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aqw | PUTATIVEOROTIDINE-MONOPHOSPHATE-DECARBOXYLASE (Plasmodiumyoelii) |
PF00215(OMPdecase) | 4 | LEU A 18TYR A 312ILE A 299GLY A 268 | NoneNoneNoneSO4 A2002 ( 4.9A) | 0.90A | 2du8A-2aqwA:undetectable | 2du8A-2aqwA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bht | CYSTEINE SYNTHASE B (Escherichiacoli) |
PF00291(PALP) | 4 | LEU A 64TYR A 85ILE A 49GLY A 56 | None | 0.94A | 2du8A-2bhtA:undetectable | 2du8A-2bhtA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfb | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Synechococcuselongatus) |
PF00202(Aminotran_3) | 4 | LEU A 378TYR A 41ILE A 376GLY A 320 | None | 0.86A | 2du8A-2cfbA:undetectable | 2du8A-2cfbA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2epk | N-ACETYL-BETA-D-GLUCOSAMINIDASE (Streptococcusgordonii) |
PF00728(Glyco_hydro_20) | 4 | LEU X 65TYR X 48ILE X 27GLY X 72 | None | 0.95A | 2du8A-2epkX:2.2 | 2du8A-2epkX:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f5u | VIRION PROTEIN UL25 (Humanalphaherpesvirus1) |
PF01499(Herpes_UL25) | 4 | LEU A 443TYR A 447ILE A 140GLY A 466 | None | 0.67A | 2du8A-2f5uA:undetectable | 2du8A-2f5uA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fcd | MYOSIN LIGHT CHAIN 1 (Saccharomycescerevisiae) |
no annotation | 4 | LEU A 31TYR A 36ILE A 34GLY A 66 | None | 0.91A | 2du8A-2fcdA:undetectable | 2du8A-2fcdA:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fwr | DNA REPAIR PROTEINRAD25 (Archaeoglobusfulgidus) |
PF04851(ResIII)PF16203(ERCC3_RAD25_C) | 4 | LEU A 271TYR A 279ILE A 329GLY A 423 | None | 0.95A | 2du8A-2fwrA:undetectable | 2du8A-2fwrA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ghs | AGR_C_1268P (Agrobacteriumfabrum) |
PF08450(SGL) | 4 | LEU A 99TYR A 312ILE A 137GLY A 133 | None | 0.88A | 2du8A-2ghsA:undetectable | 2du8A-2ghsA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2guu | ODCASE (Plasmodiumvivax) |
PF00215(OMPdecase) | 4 | LEU A 36TYR A 340ILE A 327GLY A 296 | None | 0.86A | 2du8A-2guuA:undetectable | 2du8A-2guuA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2htb | PUTATIVE ENZYMERELATED TO ALDOSE1-EPIMERASE (Salmonellaenterica) |
PF01263(Aldose_epim) | 4 | LEU A 196TYR A 211ILE A 200GLY A 241 | None | 0.91A | 2du8A-2htbA:undetectable | 2du8A-2htbA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hxg | L-ARABINOSEISOMERASE (Escherichiacoli) |
PF02610(Arabinose_Isome)PF11762(Arabinose_Iso_C) | 4 | LEU A 396TYR A 403ILE A 471GLY A 203 | None | 0.92A | 2du8A-2hxgA:undetectable | 2du8A-2hxgA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i34 | ACID PHOSPHATASE (Bacillusanthracis) |
PF03767(Acid_phosphat_B) | 4 | LEU A 66TYR A 122ILE A 151GLY A 142 | WO4 A 401 (-4.1A)NoneNoneNone | 0.67A | 2du8A-2i34A:undetectable | 2du8A-2i34A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iht | CARBOXYETHYLARGININESYNTHASE (Streptomycesclavuligerus) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | LEU A 498TYR A 499ILE A 502GLY A 270 | None | 0.71A | 2du8A-2ihtA:undetectable | 2du8A-2ihtA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j42 | C2 TOXINCOMPONENT-II (Clostridiumbotulinum) |
PF03495(Binary_toxB)PF07691(PA14)PF17475(Binary_toxB_2)PF17476(Binary_toxB_3) | 4 | LEU A 92TYR A 115ILE A 71GLY A 77 | None | 0.87A | 2du8A-2j42A:undetectable | 2du8A-2j42A:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jkd | PRE-MRNA LEAKAGEPROTEIN 1 (Saccharomycescerevisiae) |
PF00498(FHA) | 4 | LEU A 80TYR A 96ILE A 82GLY A 107 | None | 0.94A | 2du8A-2jkdA:undetectable | 2du8A-2jkdA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nq5 | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Streptococcusmutans) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | LEU A 311ILE A 313ARG A 360GLY A 359 | None | 0.74A | 2du8A-2nq5A:undetectable | 2du8A-2nq5A:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p1f | URIDINE5'-MONOPHOSPHATESYNTHASE (Homo sapiens) |
PF00215(OMPdecase) | 4 | LEU A 65TYR A 277ILE A 264GLY A 229 | None | 0.83A | 2du8A-2p1fA:undetectable | 2du8A-2p1fA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qcm | URIDINE5'-MONOPHOSPHATESYNTHASE (UMPSYNTHASE) (Homo sapiens) |
PF00215(OMPdecase) | 4 | LEU A 254TYR A 466ILE A 453GLY A 418 | NoneNoneNoneJW5 A 482 ( 4.9A) | 0.81A | 2du8A-2qcmA:undetectable | 2du8A-2qcmA:24.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qga | ADENYLOSUCCINATELYASE (Plasmodiumvivax) |
PF00206(Lyase_1)PF08328(ASL_C) | 4 | LEU B 282TYR B 276ILE B 273GLY B 178 | None | 0.86A | 2du8A-2qgaB:undetectable | 2du8A-2qgaB:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qt3 | N-ISOPROPYLAMMELIDEISOPROPYLAMIDOHYDROLASE (Pseudomonas sp.ADP) |
PF01979(Amidohydro_1) | 4 | LEU A 232TYR A 216ILE A 214GLY A 198 | None | 0.91A | 2du8A-2qt3A:undetectable | 2du8A-2qt3A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qz6 | BETA-LACTAMASE (Pseudomonasfluorescens) |
PF00144(Beta-lactamase) | 4 | LEU A 96TYR A 135ILE A 132GLY A 159 | None | 0.74A | 2du8A-2qz6A:undetectable | 2du8A-2qz6A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ri0 | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Streptococcusmutans) |
PF01182(Glucosamine_iso) | 4 | LEU A 42TYR A 43ILE A 46GLY A 32 | None | 0.93A | 2du8A-2ri0A:undetectable | 2du8A-2ri0A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhl | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 4 | LEU A 87TYR A 68ILE A 64GLY A 287 | None | 0.93A | 2du8A-2vhlA:undetectable | 2du8A-2vhlA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2za1 | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Plasmodiumfalciparum) |
PF00215(OMPdecase) | 4 | LEU A 18TYR A 309ILE A 296GLY A 265 | None | 0.92A | 2du8A-2za1A:undetectable | 2du8A-2za1A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ail | 303AA LONGHYPOTHETICALESTERASE (Sulfurisphaeratokodaii) |
PF07859(Abhydrolase_3) | 4 | LEU A 92TYR A 75ILE A 289GLY A 147 | None | 0.93A | 2du8A-3ailA:2.1 | 2du8A-3ailA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3chi | P-AMINOBENZOATEN-OXYGENASE (Streptomycesthioluteus) |
PF11583(AurF) | 5 | LEU A 206TYR A 93TYR A 61ILE A 65ARG A 96 | None | 1.30A | 2du8A-3chiA:undetectable | 2du8A-3chiA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cue | TRANSPORT PROTEINPARTICLE 31 KDASUBUNITTRANSPORT PROTEINPARTICLE 22 KDASUBUNIT (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF04051(TRAPP)PF04051(TRAPP) | 4 | LEU B 65TYR D 34ILE D 37GLY D 146 | None | 0.91A | 2du8A-3cueB:undetectable | 2du8A-3cueB:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dmk | DOWN SYNDROME CELLADHESION MOLECULE(DSCAM) ISOFORM1.30.30, N-TERMINALEIGHT IG DOMAINS (Drosophilamelanogaster) |
PF07679(I-set)PF13927(Ig_3) | 4 | LEU A 457TYR A 441ILE A 435GLY A 468 | None | 0.88A | 2du8A-3dmkA:undetectable | 2du8A-3dmkA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e59 | PYOVERDINEBIOSYNTHESIS PROTEINPVCA (Pseudomonasaeruginosa) |
PF05141(DIT1_PvcA) | 4 | LEU A 94ILE A 108ARG A 22GLY A 265 | None | 0.87A | 2du8A-3e59A:undetectable | 2du8A-3e59A:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3els | PRE-MRNA LEAKAGEPROTEIN 1 (Saccharomycescerevisiae) |
PF00498(FHA) | 4 | LEU A 80TYR A 96ILE A 82GLY A 107 | None | 0.90A | 2du8A-3elsA:undetectable | 2du8A-3elsA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fk5 | 3-OXOACYL-SYNTHASEIII (Xanthomonasoryzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | LEU A 305ILE A 320ARG A 313GLY A 312 | None | 0.90A | 2du8A-3fk5A:undetectable | 2du8A-3fk5A:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7k | AGMATINE DEIMINASE (Arabidopsisthaliana) |
PF04371(PAD_porph) | 4 | LEU A 203ILE A 118ARG A 93GLY A 164 | NoneNoneNoneAGT A 366 ( 3.5A) | 0.82A | 2du8A-3h7kA:undetectable | 2du8A-3h7kA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kiz | PHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Cytophagahutchinsonii) |
PF02769(AIRS_C) | 4 | LEU A 380TYR A 392ILE A 382GLY A 291 | None | 0.88A | 2du8A-3kizA:undetectable | 2du8A-3kizA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kvt | POTASSIUM CHANNELPROTEIN SHAW (Aplysiacalifornica) |
PF02214(BTB_2) | 4 | LEU A 74TYR A 76ILE A 65GLY A 82 | None | 0.83A | 2du8A-3kvtA:undetectable | 2du8A-3kvtA:14.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdo | PUTATIVEPHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Parabacteroidesdistasonis) |
PF02769(AIRS_C) | 4 | LEU A 377TYR A 388ILE A 379GLY A 290 | None | 0.90A | 2du8A-3mdoA:undetectable | 2du8A-3mdoA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rr1 | PUTATIVED-GALACTONATEDEHYDRATASE (Ralstoniapickettii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 223TYR A 220ILE A 231GLY A 186 | None | 0.95A | 2du8A-3rr1A:undetectable | 2du8A-3rr1A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sr7 | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Streptococcusmutans) |
PF01070(FMN_dh) | 4 | LEU A 27TYR A 319ILE A 25GLY A 266 | None | 0.75A | 2du8A-3sr7A:undetectable | 2du8A-3sr7A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpy | FHADOMAIN-CONTAININGPROTEIN DDL (Arabidopsisthaliana) |
PF00498(FHA) | 4 | LEU A 19TYR A 126ILE A 117GLY A 43 | None | 0.94A | 2du8A-3vpyA:undetectable | 2du8A-3vpyA:17.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w4k | D-AMINO-ACID OXIDASE (Homo sapiens) |
PF01266(DAO) | 5 | LEU A 215TYR A 228ILE A 230ARG A 283GLY A 313 | 3LD A 402 (-4.1A)3LD A 402 (-3.8A)None3LD A 402 (-3.7A)3LD A 402 ( 3.6A) | 0.35A | 2du8A-3w4kA:55.2 | 2du8A-3w4kA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w4k | D-AMINO-ACID OXIDASE (Homo sapiens) |
PF01266(DAO) | 4 | TYR A 224TYR A 228ARG A 283GLY A 313 | 3LD A 402 (-3.6A)3LD A 402 (-3.8A)3LD A 402 (-3.7A)3LD A 402 ( 3.6A) | 0.74A | 2du8A-3w4kA:55.2 | 2du8A-3w4kA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wrt | BETA-LACTAMASE (Chromohalobactersp. 560) |
PF00144(Beta-lactamase) | 4 | LEU A 120TYR A 151ILE A 293GLY A 64 | None | 0.78A | 2du8A-3wrtA:undetectable | 2du8A-3wrtA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zx2 | ECTONUCLEOSIDETRIPHOSPHATEDIPHOSPHOHYDROLASE 1 (Rattusnorvegicus) |
PF01150(GDA1_CD39) | 4 | LEU A 105TYR A 104ILE A 101GLY A 56 | None | 0.93A | 2du8A-3zx2A:undetectable | 2du8A-3zx2A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ap3 | STEROIDMONOOXYGENASE (Rhodococcusrhodochrous) |
PF00743(FMO-like) | 4 | LEU A 105TYR A 79TYR A 104ILE A 101 | None | 0.93A | 2du8A-4ap3A:7.0 | 2du8A-4ap3A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 4 | LEU V 163TYR V 143ILE V 165GLY V1056 | None | 0.91A | 2du8A-4bxsV:undetectable | 2du8A-4bxsV:12.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4czt | CBL-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 23 (Arabidopsisthaliana) |
PF00069(Pkinase) | 4 | LEU A 240TYR A 241ILE A 244GLY A 193 | None | 0.77A | 2du8A-4cztA:undetectable | 2du8A-4cztA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d1i | BETA-GALACTOSIDASE,PUTATIVE, BGL35A (Cellvibriojaponicus) |
PF02449(Glyco_hydro_42) | 4 | LEU A 51TYR A 58ILE A 198GLY A 62 | None | 0.87A | 2du8A-4d1iA:undetectable | 2du8A-4d1iA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4djm | DRAB (Escherichiacoli) |
PF00345(PapD_N)PF02753(PapD_C) | 4 | LEU A 145TYR A 33ILE A 88GLY A 92 | None | 0.92A | 2du8A-4djmA:undetectable | 2du8A-4djmA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dnh | UNCHARACTERIZEDPROTEIN (Sinorhizobiummeliloti) |
PF06187(DUF993) | 4 | LEU A 180TYR A 176ILE A 189GLY A 121 | None | 0.93A | 2du8A-4dnhA:undetectable | 2du8A-4dnhA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4es4 | PUTATIVE CYCLICDI-GMP REGULATORCDGR (Escherichiacoli) |
PF00563(EAL) | 4 | LEU A 121TYR A 118ILE A 114GLY A 129 | None | 0.93A | 2du8A-4es4A:undetectable | 2du8A-4es4A:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fys | AMINOPEPTIDASE N (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | LEU A 346TYR A 194ILE A 283GLY A 192 | None | 0.95A | 2du8A-4fysA:undetectable | 2du8A-4fysA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0b | HYDROXYCINNAMOYL-COASHIKIMATE/QUINATEHYDROXYCINNAMOYLTRANSFERASE (Coffeacanephora) |
PF02458(Transferase) | 5 | LEU A 147TYR A 42TYR A 40ILE A 165GLY A 385 | None | 1.47A | 2du8A-4g0bA:undetectable | 2du8A-4g0bA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iu9 | NITRITE EXTRUSIONPROTEIN 2 (Escherichiacoli) |
no annotation | 4 | LEU B 404ILE B 407ARG B 303GLY B 364 | None | 0.84A | 2du8A-4iu9B:undetectable | 2du8A-4iu9B:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0m | SERINE/THREONINE-PROTEIN KINASEBRI1-LIKE 1 (Arabidopsisthaliana) |
PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 4 | LEU A 670TYR A 659ILE A 675GLY A 565 | None | 0.92A | 2du8A-4j0mA:undetectable | 2du8A-4j0mA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4luj | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Methanocaldococcusjannaschii) |
PF00215(OMPdecase) | 4 | LEU A 24TYR A 227ILE A 214GLY A 187 | None | 0.88A | 2du8A-4lujA:undetectable | 2du8A-4lujA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mjz | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Toxoplasmagondii) |
PF00215(OMPdecase) | 4 | LEU A 40TYR A 302ILE A 289GLY A 258 | None | 0.85A | 2du8A-4mjzA:undetectable | 2du8A-4mjzA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6c | UNCHARACTERIZEDPROTEIN (Streptococcuspneumoniae) |
PF08020(DUF1706) | 4 | LEU A 106TYR A 21ILE A 110GLY A 158 | None | 0.92A | 2du8A-4n6cA:undetectable | 2du8A-4n6cA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8s | PUTATIVE (Helicobacterpylori) |
PF08843(AbiEii) | 4 | LEU A 112TYR A 95ILE A 114GLY A 68 | None | 0.79A | 2du8A-4o8sA:undetectable | 2du8A-4o8sA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ok0 | PUTATIVE (Helicobacterpylori) |
PF08843(AbiEii) | 4 | LEU A 112TYR A 95ILE A 114GLY A 68 | None | 0.74A | 2du8A-4ok0A:undetectable | 2du8A-4ok0A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgi | UNCHARACTERIZEDPROTEIN (Yersinia pestis) |
PF13619(KTSC) | 4 | LEU A 23TYR A 35ILE A 25GLY A 58 | None | 0.81A | 2du8A-4rgiA:undetectable | 2du8A-4rgiA:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4weo | PUTATIVEACETOIN(DIACETYL)REDUCTASE (Burkholderiacenocepacia) |
PF00106(adh_short) | 4 | LEU A 153TYR A 156ILE A 95GLY A 187 | None | 0.81A | 2du8A-4weoA:6.2 | 2du8A-4weoA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xeu | TRANSKETOLASE (Pseudomonasaeruginosa) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | LEU A 601TYR A 589TYR A 622ILE A 555GLY A 539 | None | 1.20A | 2du8A-4xeuA:undetectable | 2du8A-4xeuA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhj | ENVELOPEGLYCOPROTEIN H (Humanalphaherpesvirus3) |
PF02489(Herpes_glycop_H)PF17488(Herpes_glycoH_C) | 4 | TYR A 364TYR A 365ILE A 271GLY A 248 | None | 0.95A | 2du8A-4xhjA:undetectable | 2du8A-4xhjA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zu9 | ELONGATION FACTORSELB (Aquifexaeolicus) |
PF00009(GTP_EFTU)PF09107(SelB-wing_3) | 4 | LEU A 451TYR A 457ILE A 417GLY A 430 | None | 0.93A | 2du8A-4zu9A:undetectable | 2du8A-4zu9A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ah0 | LIPASE (Pelosinusfermentans) |
no annotation | 4 | LEU A 367TYR A 277ILE A 174GLY A 390 | None | 0.87A | 2du8A-5ah0A:undetectable | 2du8A-5ah0A:25.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b37 | TRYPTOPHANDEHYDROGENASE (Nostocpunctiforme) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | LEU A 270TYR A 277ILE A 252GLY A 237 | None | 0.69A | 2du8A-5b37A:3.8 | 2du8A-5b37A:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5es6 | LINEAR GRAMICIDINSYNTHASE SUBUNIT A (Brevibacillusparabrevis) |
PF00501(AMP-binding)PF00551(Formyl_trans_N) | 4 | LEU A 400TYR A 439ILE A 460GLY A 482 | None | 0.95A | 2du8A-5es6A:undetectable | 2du8A-5es6A:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5es9 | LINEAR GRAMICIDINSYNTHETASE SUBUNIT A (Brevibacillusparabrevis) |
PF00501(AMP-binding)PF00550(PP-binding)PF00551(Formyl_trans_N)PF13193(AMP-binding_C) | 4 | LEU A 400TYR A 439ILE A 460GLY A 482 | None | 0.91A | 2du8A-5es9A:undetectable | 2du8A-5es9A:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gjw | VOLTAGE-DEPENDENTCALCIUM CHANNELSUBUNITALPHA-2/DELTA-1 (Oryctolaguscuniculus) |
PF00092(VWA)PF08399(VWA_N)PF08473(VGCC_alpha2) | 4 | LEU F 889TYR F 895ILE F1019GLY F 859 | None | 0.94A | 2du8A-5gjwF:undetectable | 2du8A-5gjwF:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihe | DNA POLYMERASE IISMALL SUBUNIT (Pyrococcusabyssi) |
PF00149(Metallophos) | 4 | LEU A 431TYR A 428ILE A 471GLY A 449 | None | 0.89A | 2du8A-5iheA:undetectable | 2du8A-5iheA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jnf | LINEAR GRAMICIDINSYNTHASE SUBUNIT A (Brevibacillusparabrevis) |
no annotation | 4 | LEU C 400TYR C 439ILE C 460GLY C 482 | NoneFMT C 604 (-4.9A)NoneNone | 0.93A | 2du8A-5jnfC:undetectable | 2du8A-5jnfC:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jnm | MANNITOL-1-PHOSPHATE5-DEHYDROGENASE (Staphylococcusaureus) |
no annotation | 4 | LEU A 40TYR A 46ILE A 36GLY A 14 | None | 0.83A | 2du8A-5jnmA:4.3 | 2du8A-5jnmA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jsb | INDUCED MYELOIDLEUKEMIA CELLDIFFERENTIATIONPROTEIN MCL-1 (Homo sapiens) |
PF00452(Bcl-2) | 4 | LEU A 186TYR A 185ILE A 294GLY A 217 | None | 0.87A | 2du8A-5jsbA:undetectable | 2du8A-5jsbA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kjv | HYDROXYCINNAMOYLTRANSFERASE (Plectranthusscutellarioides) |
PF02458(Transferase) | 5 | LEU A 147TYR A 42TYR A 40ILE A 165GLY A 378 | None | 1.49A | 2du8A-5kjvA:undetectable | 2du8A-5kjvA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2h | CENTYRIN (syntheticconstruct) |
PF00041(fn3) | 4 | LEU A 20TYR A 57ILE A 34GLY A 61 | None | 0.95A | 2du8A-5l2hA:undetectable | 2du8A-5l2hA:14.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l8s | AMINO ACYL PEPTIDASE (Sporosarcinapsychrophila) |
PF00326(Peptidase_S9) | 4 | LEU A 272TYR A 261ILE A 305GLY A 301 | None | 0.95A | 2du8A-5l8sA:undetectable | 2du8A-5l8sA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mev | INDUCED MYELOIDLEUKEMIA CELLDIFFERENTIATIONPROTEIN MCL-1HOMOLOG,INDUCEDMYELOID LEUKEMIACELL DIFFERENTIATIONPROTEIN MCL-1 (Homo sapiens;Mus musculus) |
PF00452(Bcl-2) | 4 | LEU A 186TYR A 185ILE A 294GLY A 217 | None | 0.90A | 2du8A-5mevA:undetectable | 2du8A-5mevA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5min | QUINOPROTEIN GLUCOSEDEHYDROGENASE B (Acinetobactercalcoaceticus) |
no annotation | 4 | LEU A 149TYR A 95ILE A 151GLY A 206 | None | 0.91A | 2du8A-5minA:undetectable | 2du8A-5minA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | LEU A1615TYR A1618ILE A1557GLY A1642 | None | 0.92A | 2du8A-5nugA:undetectable | 2du8A-5nugA:5.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ool | 39S RIBOSOMALPROTEIN L37,MITOCHONDRIAL (Homo sapiens) |
PF07147(PDCD9) | 4 | LEU 5 382TYR 5 383ILE 5 158ARG 5 173 | NoneNoneNone A A2395 ( 3.0A) | 0.95A | 2du8A-5ool5:undetectable | 2du8A-5ool5:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr1 | CHLORIDE CHANNELPROTEIN (Bos taurus) |
PF00654(Voltage_CLC) | 4 | LEU A 139TYR A 138ILE A 129GLY A 204 | None | 0.94A | 2du8A-5tr1A:undetectable | 2du8A-5tr1A:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vkq | NO MECHANORECEPTORPOTENTIAL C ISOFORML (Drosophilamelanogaster) |
PF00023(Ank)PF00520(Ion_trans)PF12796(Ank_2)PF13637(Ank_4) | 4 | LEU A1016TYR A1011ILE A1007GLY A 971 | None | 0.91A | 2du8A-5vkqA:undetectable | 2du8A-5vkqA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsq | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 4 | LEU A 96TYR A 93ILE A 87GLY A 38 | None | 0.93A | 2du8A-5xsqA:undetectable | 2du8A-5xsqA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtc | ACYL CARRIERPROTEIN,MITOCHONDRIAL (Homo sapiens) |
PF00550(PP-binding) | 4 | LEU X 87TYR X 90ILE X 118GLY X 109 | None | 0.95A | 2du8A-5xtcX:undetectable | 2du8A-5xtcX:12.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6any | BM4233, ISOFORM B (Brugia malayi) |
no annotation | 4 | LEU A 176TYR A 100ILE A 166GLY A 120 | None | 0.67A | 2du8A-6anyA:undetectable | 2du8A-6anyA:undetectable |