SIMILAR PATTERNS OF AMINO ACIDS FOR 2DQY_C_CHDC3_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 4 | LEU A 162LEU A 130PRO A 138VAL A 95 | None | 1.19A | 2dqyC-1cs1A:undetectable | 2dqyC-1cs1A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e51 | DELTA-AMINOLEVULINICACID DEHYDRATASE (Homo sapiens) |
PF00490(ALAD) | 4 | LEU A 155LEU A 182PRO A 167VAL A 193 | None | 1.20A | 2dqyC-1e51A:0.9 | 2dqyC-1e51A:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hci | ALPHA-ACTININ 2 (Homo sapiens) |
PF00435(Spectrin) | 4 | LEU A 289LEU A 341PRO A 362VAL A 368 | None | 1.19A | 2dqyC-1hciA:undetectable | 2dqyC-1hciA:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iap | GUANINE NUCLEOTIDEEXCHANGE FACTORP115RHOGEF (Homo sapiens) |
PF09128(RGS-like) | 4 | TRP A 168LEU A 59LEU A 63PRO A 167 | None | 1.19A | 2dqyC-1iapA:undetectable | 2dqyC-1iapA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jyo | PROTEIN TYROSINEPHOSPHATASE SPTP (Salmonellaenterica) |
PF09119(SicP-binding) | 4 | LEU E 53LEU E 80PRO E 57VAL E 65 | None | 1.03A | 2dqyC-1jyoE:undetectable | 2dqyC-1jyoE:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | LEU A 488LEU A 620PRO A 503VAL A 589 | None | 1.05A | 2dqyC-1l5jA:0.3 | 2dqyC-1l5jA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mt5 | FATTY-ACID AMIDEHYDROLASE (Rattusnorvegicus) |
PF01425(Amidase) | 4 | LEU A 234LEU A 174PRO A 231VAL A 137 | None | 1.05A | 2dqyC-1mt5A:0.0 | 2dqyC-1mt5A:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mvl | PPC DECARBOXYLASEATHAL3A (Arabidopsisthaliana) |
PF02441(Flavoprotein) | 4 | LEU A 38LEU A 24PRO A 66VAL A 69 | None | 1.14A | 2dqyC-1mvlA:1.5 | 2dqyC-1mvlA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n94 | PROTEINFARNESYLTRANSFERASEBETA SUBUNIT (Rattusnorvegicus) |
PF00432(Prenyltrans) | 4 | LEU B 311LEU B 256PRO B 399VAL B 400 | None | 1.07A | 2dqyC-1n94B:undetectable | 2dqyC-1n94B:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odi | PURINE NUCLEOSIDEPHOSPHORYLASE (Thermusthermophilus) |
PF01048(PNP_UDP_1) | 4 | LEU A 34LEU A 229PRO A 20VAL A 88 | None | 1.19A | 2dqyC-1odiA:undetectable | 2dqyC-1odiA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pby | QUINOHEMOPROTEINAMINE DEHYDROGENASE60 KDA SUBUNIT (Paracoccusdenitrificans) |
PF09098(Dehyd-heme_bind)PF09099(Qn_am_d_aIII)PF09100(Qn_am_d_aIV)PF14930(Qn_am_d_aII) | 4 | LEU A 340LEU A 325PRO A 308VAL A 311 | None | 1.05A | 2dqyC-1pbyA:undetectable | 2dqyC-1pbyA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qs8 | PLASMEPSIN (Plasmodiumvivax) |
PF00026(Asp) | 4 | LEU A 96LYS A 148LEU A 143PRO A 99 | None | 1.19A | 2dqyC-1qs8A:0.0 | 2dqyC-1qs8A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1twl | INORGANICPYROPHOSPHATASE (Pyrococcusfuriosus) |
PF00719(Pyrophosphatase) | 4 | LEU A 130LEU A 107PRO A 53VAL A 54 | None | 1.09A | 2dqyC-1twlA:undetectable | 2dqyC-1twlA:14.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ukw | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | LEU A 82LEU A 150PRO A 69VAL A 68 | None | 1.21A | 2dqyC-1ukwA:0.4 | 2dqyC-1ukwA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v31 | HYPOTHETICAL PROTEINRAFL11-05-P19 (Arabidopsisthaliana) |
PF02201(SWIB) | 4 | TRP A 37LEU A 45LEU A 60VAL A 74 | None | 1.18A | 2dqyC-1v31A:undetectable | 2dqyC-1v31A:12.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wlo | SUFE PROTEIN (Thermusthermophilus) |
PF02657(SufE) | 4 | LEU A 107LEU A 10PRO A 98VAL A 2 | None | 1.21A | 2dqyC-1wloA:undetectable | 2dqyC-1wloA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zof | ALKYLHYDROPEROXIDE-REDUCTASE (Helicobacterpylori) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | LEU A 31LEU A 27PRO A 100VAL A 102 | None | 1.16A | 2dqyC-1zofA:undetectable | 2dqyC-1zofA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a9c | SULFITE OXIDASE (Gallus gallus) |
PF00174(Oxidored_molyb)PF03404(Mo-co_dimer) | 4 | LEU A 415LEU A 386PRO A 354VAL A 462 | None | 1.12A | 2dqyC-2a9cA:undetectable | 2dqyC-2a9cA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2imr | HYPOTHETICAL PROTEINDR_0824 (Deinococcusradiodurans) |
PF01979(Amidohydro_1) | 4 | LEU A 233LEU A 193PRO A 210VAL A 174 | None | 1.11A | 2dqyC-2imrA:undetectable | 2dqyC-2imrA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o6x | SECRETED CATHEPSIN L1 (Fasciolahepatica) |
PF00112(Peptidase_C1)PF08246(Inhibitor_I29) | 4 | LEU A 151LEU A 180PRO A 311VAL A 313 | None | 1.03A | 2dqyC-2o6xA:undetectable | 2dqyC-2o6xA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q9k | UNCHARACTERIZEDPROTEIN (Exiguobacteriumsibiricum) |
no annotation | 4 | LEU A 9LEU A 84PRO A 21VAL A 23 | None | 1.03A | 2dqyC-2q9kA:undetectable | 2dqyC-2q9kA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3h | K5 LYASE (Escherichiavirus K1-5) |
no annotation | 4 | LEU A 94LEU A 104PRO A 99VAL A 131 | None | 1.17A | 2dqyC-2x3hA:undetectable | 2dqyC-2x3hA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xci | 3-DEOXY-D-MANNO-2-OCTULOSONIC ACIDTRANSFERASE (Aquifexaeolicus) |
PF04413(Glycos_transf_N) | 4 | LEU A 74LEU A 105PRO A 91VAL A 111 | None | 1.12A | 2dqyC-2xciA:2.8 | 2dqyC-2xciA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yu1 | JMJCDOMAIN-CONTAININGHISTONEDEMETHYLATIONPROTEIN 1A (Homo sapiens) |
PF02373(JmjC) | 4 | LEU A 76LEU A 72PRO A 160VAL A 163 | None | 1.07A | 2dqyC-2yu1A:undetectable | 2dqyC-2yu1A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b33 | SENSOR PROTEIN (Vibrioparahaemolyticus) |
PF00989(PAS) | 4 | LEU A 60LEU A 58PRO A 66VAL A 93 | None | 1.17A | 2dqyC-3b33A:undetectable | 2dqyC-3b33A:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b4w | ALDEHYDEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00171(Aldedh) | 4 | LEU A 160LEU A 192PRO A 181VAL A 208 | None | 1.15A | 2dqyC-3b4wA:undetectable | 2dqyC-3b4wA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c3p | METHYLTRANSFERASE (Geobactersulfurreducens) |
PF01596(Methyltransf_3) | 4 | LEU A 142LEU A 149PRO A 62VAL A 60 | None | 0.95A | 2dqyC-3c3pA:undetectable | 2dqyC-3c3pA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c64 | PFEMP1 VARIANT 2 OFSTRAIN MC (Plasmodiumfalciparum) |
PF03011(PFEMP) | 4 | TRP A 25LEU A 19LEU A 148VAL A 56 | PG4 A 301 (-3.6A)NoneNoneNone | 1.12A | 2dqyC-3c64A:undetectable | 2dqyC-3c64A:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cdl | TRANSCRIPTIONALREGULATOR AEFR (Pseudomonassyringae groupgenomosp. 3) |
PF00440(TetR_N)PF14246(TetR_C_7) | 4 | TRP A 195LEU A 193LEU A 144VAL A 147 | None | 1.09A | 2dqyC-3cdlA:undetectable | 2dqyC-3cdlA:15.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cia | COLD-ACTIVEAMINOPEPTIDASE (Colwelliapsychrerythraea) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 4 | LEU A 88LEU A 74PRO A 228VAL A 188 | None | 1.05A | 2dqyC-3ciaA:undetectable | 2dqyC-3ciaA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dcy | REGULATOR PROTEIN (Homo sapiens) |
PF00300(His_Phos_1) | 4 | LEU A 139LEU A 6PRO A 250VAL A 252 | None | 1.05A | 2dqyC-3dcyA:undetectable | 2dqyC-3dcyA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gue | UTP-GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE2 (Trypanosomabrucei) |
PF01704(UDPGP) | 4 | LYS A 237LEU A 239PRO A 58VAL A 364 | None | 1.16A | 2dqyC-3gueA:undetectable | 2dqyC-3gueA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hvd | PROTECTIVE ANTIGEN (Bacillusanthracis) |
PF03495(Binary_toxB)PF17475(Binary_toxB_2)PF17476(Binary_toxB_3) | 4 | LEU A 187LEU A 203PRO A 254VAL A 239 | None | 0.94A | 2dqyC-3hvdA:undetectable | 2dqyC-3hvdA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i1l | HEMAGGLUTININ-ESTERASE PROTEIN (Porcinetorovirus) |
PF02710(Hema_HEFG)PF03996(Hema_esterase) | 4 | LEU A 349LEU A 65PRO A 33VAL A 102 | None | 1.18A | 2dqyC-3i1lA:undetectable | 2dqyC-3i1lA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i2t | EPIDERMAL GROWTHFACTOR RECEPTOR,ISOFORM A (Drosophilamelanogaster) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 4 | TRP A 41LEU A 39LEU A 42PRO A 13 | None | 1.19A | 2dqyC-3i2tA:undetectable | 2dqyC-3i2tA:20.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k9b | LIVERCARBOXYLESTERASE 1 (Homo sapiens) |
PF00135(COesterase) | 5 | TRP A1357LEU A1368LEU A1418PRO A1461VAL A1464 | None | 0.42A | 2dqyC-3k9bA:61.6 | 2dqyC-3k9bA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l12 | PUTATIVEGLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Ruegeriapomeroyi) |
PF03009(GDPD) | 4 | TRP A 273LEU A 247LEU A 146VAL A 293 | UNL A 317 ( 4.1A)NoneNoneNone | 1.02A | 2dqyC-3l12A:undetectable | 2dqyC-3l12A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3la8 | PUTATIVE PURINENUCLEOSIDEPHOSPHORYLASE (Streptococcusmutans) |
PF01048(PNP_UDP_1) | 4 | LEU A 78LEU A 65PRO A 22VAL A 19 | None | 1.18A | 2dqyC-3la8A:undetectable | 2dqyC-3la8A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lov | PROTOPORPHYRINOGENOXIDASE (Exiguobacteriumsibiricum) |
PF01593(Amino_oxidase) | 4 | LEU A 405LYS A 43PRO A 410VAL A 444 | FAD A 500 ( 4.0A)FAD A 500 (-2.8A)NoneFAD A 500 (-4.9A) | 1.08A | 2dqyC-3lovA:undetectable | 2dqyC-3lovA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxy | 4-HYDROXYTHREONINE-4-PHOSPHATEDEHYDROGENASE (Yersinia pestis) |
PF04166(PdxA) | 4 | LEU A 45LEU A 57PRO A 12VAL A 37 | None | 0.96A | 2dqyC-3lxyA:undetectable | 2dqyC-3lxyA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwt | NUCLEOPROTEIN (Lassamammarenavirus) |
PF00843(Arena_nucleocap)PF17290(Arena_ncap_C) | 4 | LEU A 307LEU A 279PRO A 318VAL A 270 | None | 0.80A | 2dqyC-3mwtA:undetectable | 2dqyC-3mwtA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvt | 3-DEOXY-D-ARABINO-HEPTULOSONATE7-PHOSPHATE SYNTHASE (Listeriamonocytogenes) |
PF00793(DAHP_synth_1)PF01817(CM_2) | 4 | LEU A 112LEU A 148PRO A 227VAL A 204 | None | 1.08A | 2dqyC-3nvtA:undetectable | 2dqyC-3nvtA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pp8 | GLYOXYLATE/HYDROXYPYRUVATE REDUCTASE A (Salmonellaenterica) |
PF02826(2-Hacid_dh_C) | 4 | LEU A 71LEU A 87PRO A 47VAL A 44 | None | 0.98A | 2dqyC-3pp8A:undetectable | 2dqyC-3pp8A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q46 | TT-IPPASE (Thermococcusthioreducens) |
PF00719(Pyrophosphatase) | 4 | LEU A 130LEU A 107PRO A 53VAL A 54 | None | 1.11A | 2dqyC-3q46A:undetectable | 2dqyC-3q46A:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qg7 | AP4-24H11 ANTIBODYHEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | LEU H 80LEU H 82PRO H 9VAL H 12 | None | 1.19A | 2dqyC-3qg7H:undetectable | 2dqyC-3qg7H:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rfr | PMOA (Methylocystissp. M) |
no annotation | 4 | TRP J 157LEU J 155LEU J 159PRO J 70 | None | 1.20A | 2dqyC-3rfrJ:undetectable | 2dqyC-3rfrJ:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rot | ABC SUGARTRANSPORTER,PERIPLASMIC SUGARBINDING PROTEIN (Legionellapneumophila) |
PF13407(Peripla_BP_4) | 4 | LEU A 227LEU A 252PRO A 238VAL A 240 | None | 1.21A | 2dqyC-3rotA:2.3 | 2dqyC-3rotA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3scy | HYPOTHETICALBACTERIAL6-PHOSPHOGLUCONOLACTONASE (Bacteroidesfragilis) |
PF10282(Lactonase) | 4 | LEU A 193LEU A 268PRO A 236VAL A 230 | None | 1.14A | 2dqyC-3scyA:undetectable | 2dqyC-3scyA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sn0 | PUTATIVEL-ALANINE-DL-GLUTAMATE EPIMERASE (Paraburkholderiaxenovorans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 216LEU A 201PRO A 125VAL A 145 | None | 1.15A | 2dqyC-3sn0A:2.2 | 2dqyC-3sn0A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sr2 | NON-HOMOLOGOUSEND-JOINING FACTOR 1 (Homo sapiens) |
PF09302(XLF) | 4 | LEU C 8LYS C 26LEU C 37PRO C 138 | None | 1.14A | 2dqyC-3sr2C:undetectable | 2dqyC-3sr2C:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5q | NUCLEOPROTEIN (Mopeia Lassavirusreassortant 29) |
PF00843(Arena_nucleocap) | 4 | LEU A 307LEU A 279PRO A 318VAL A 270 | None | 0.83A | 2dqyC-3t5qA:undetectable | 2dqyC-3t5qA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tex | PROTECTIVE ANTIGEN (Bacillusanthracis) |
PF03495(Binary_toxB)PF07691(PA14)PF17475(Binary_toxB_2)PF17476(Binary_toxB_3) | 4 | LEU A 187LEU A 203PRO A 254VAL A 239 | None | 0.94A | 2dqyC-3texA:undetectable | 2dqyC-3texA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uav | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE (Bacillus cereus) |
PF01048(PNP_UDP_1) | 4 | LEU A 33LEU A 229PRO A 19VAL A 88 | None | 1.13A | 2dqyC-3uavA:undetectable | 2dqyC-3uavA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w5f | BETA-GALACTOSIDASE (Solanumlycopersicum) |
PF01301(Glyco_hydro_35) | 4 | LEU A 316LYS A 62LEU A 59PRO A 631 | None | 1.05A | 2dqyC-3w5fA:undetectable | 2dqyC-3w5fA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvu | BETA-MANNOSIDASE (Trichodermaharzianum) |
PF00703(Glyco_hydro_2) | 4 | TRP A 175LEU A 510LEU A 495VAL A 179 | NoneNAG A1956 (-4.3A)NoneNone | 1.10A | 2dqyC-4cvuA:undetectable | 2dqyC-4cvuA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4di5 | 5-EPI-ARISTOLOCHENESYNTHASE (Nicotianatabacum) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | LEU A 433LEU A 426PRO A 500VAL A 501 | None | 1.21A | 2dqyC-4di5A:2.5 | 2dqyC-4di5A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ds2 | UBIQUITIN-CONJUGATING ENZYME E2,PUTATIVE (Trypanosomacruzi) |
PF00179(UQ_con) | 4 | LEU A 16LEU A 50PRO A 82VAL A 84 | None | 1.17A | 2dqyC-4ds2A:undetectable | 2dqyC-4ds2A:14.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4en2 | AP-1 COMPLEX SUBUNITMU-1 (Mus musculus) |
no annotation | 4 | LEU M 212LEU M 173PRO M 257VAL M 202 | None | 1.19A | 2dqyC-4en2M:undetectable | 2dqyC-4en2M:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hb4 | EXPORTIN-1 (Saccharomycescerevisiae) |
PF03810(IBN_N)PF08389(Xpo1)PF08767(CRM1_C) | 4 | LEU C 55LYS C 64LEU C 114VAL C 107 | NoneNone CL C1106 ( 4.4A)None | 1.12A | 2dqyC-4hb4C:undetectable | 2dqyC-4hb4C:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3u | ALDEHYDEDEHYDROGENASE (NAD+) (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 4 | LEU A 161LEU A 193PRO A 182VAL A 209 | None | 1.16A | 2dqyC-4i3uA:undetectable | 2dqyC-4i3uA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ikh | GLUTATHIONES-TRANSFERASE (Pseudomonasprotegens) |
PF00043(GST_C)PF02798(GST_N) | 4 | TRP A 189LEU A 119LEU A 94PRO A 188 | GSH A 303 (-4.3A)NoneNoneNone | 1.21A | 2dqyC-4ikhA:undetectable | 2dqyC-4ikhA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iug | BETA-GALACTOSIDASE A (Aspergillusoryzae) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | LEU A 610LEU A 615PRO A 576VAL A 599 | None | 1.10A | 2dqyC-4iugA:undetectable | 2dqyC-4iugA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jzt | DGTPPYROPHOSPHOHYDROLASE (Bacillussubtilis) |
PF00293(NUDIX) | 4 | LEU A 121LEU A 107PRO A 51VAL A 69 | None | 0.82A | 2dqyC-4jztA:undetectable | 2dqyC-4jztA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jzu | RNAPYROPHOSPHOHYDROLASE (Bacillussubtilis) |
PF00293(NUDIX) | 4 | LEU A 121LEU A 107PRO A 51VAL A 69 | None | 0.99A | 2dqyC-4jzuA:undetectable | 2dqyC-4jzuA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7o | IRON-BINDING PROTEIN (Staphylococcusepidermidis) |
PF01497(Peripla_BP_2) | 4 | LEU A 87LEU A 114PRO A 97VAL A 122 | None | 1.21A | 2dqyC-4m7oA:undetectable | 2dqyC-4m7oA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nmy | ABC-TYPE TRANSPORTSYSTEM,EXTRACELLULARSOLUTE-BINDINGPROTEIN (Clostridioidesdifficile) |
PF09084(NMT1) | 4 | LEU A 10LEU A 21PRO A 192VAL A 84 | None | 1.08A | 2dqyC-4nmyA:undetectable | 2dqyC-4nmyA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oal | CYTOKININDEHYDROGENASE 4 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | TRP A 156LEU A 154LEU A 158PRO A 131 | None | 1.12A | 2dqyC-4oalA:undetectable | 2dqyC-4oalA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmd | ENDO-1,4-BETA-XYLANASE (Caldicellulosiruptorbescii) |
PF00331(Glyco_hydro_10) | 4 | LEU A 89LEU A 116PRO A 96VAL A 99 | None | 1.19A | 2dqyC-4pmdA:undetectable | 2dqyC-4pmdA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qku | HYDROLASE (Burkholderiacenocepacia) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 4 | LEU A 246LEU A 360PRO A 133VAL A 134 | None | 1.12A | 2dqyC-4qkuA:undetectable | 2dqyC-4qkuA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qyj | ALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00171(Aldedh) | 4 | LEU A 172LEU A 204PRO A 193VAL A 220 | None | 1.19A | 2dqyC-4qyjA:undetectable | 2dqyC-4qyjA:24.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4raf | PROTEIN PHOSPHATASE1A (Homo sapiens) |
PF00481(PP2C)PF07830(PP2C_C) | 4 | LEU A 46LEU A 133PRO A 92VAL A 97 | None | 1.06A | 2dqyC-4rafA:undetectable | 2dqyC-4rafA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | LEU A2260LEU A2504PRO A2448VAL A2449 | None | 1.04A | 2dqyC-4rh7A:undetectable | 2dqyC-4rh7A:9.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tym | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE (Streptococcusagalactiae) |
PF01048(PNP_UDP_1) | 4 | LEU A 55LEU A 252PRO A 41VAL A 110 | None | 1.18A | 2dqyC-4tymA:undetectable | 2dqyC-4tymA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uip | REPEBODY (RAC1) (Listeriamonocytogenes;Eptatretusburgeri;syntheticconstruct) |
PF11921(DUF3439)PF12354(Internalin_N)PF13855(LRR_8) | 4 | LEU B 76LEU B 82PRO B 102VAL B 105 | None | 1.14A | 2dqyC-4uipB:undetectable | 2dqyC-4uipB:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wui | N-(5'-PHOSPHORIBOSYL)ANTHRANILATEISOMERASE (Jonesiadenitrificans) |
PF00697(PRAI) | 4 | LEU A 150LEU A 121PRO A 145VAL A 114 | None | 1.12A | 2dqyC-4wuiA:undetectable | 2dqyC-4wuiA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ydo | UNCHARACTERIZEDPROTEIN (Candidaalbicans) |
PF00432(Prenyltrans) | 4 | LEU B 444LEU B 376PRO B 555VAL B 556 | None | 1.04A | 2dqyC-4ydoB:undetectable | 2dqyC-4ydoB:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzw | AGAP004976-PA (Anophelesgambiae) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | TRP A 596LEU A 602LEU A 545VAL A 568 | None | 1.13A | 2dqyC-4yzwA:undetectable | 2dqyC-4yzwA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgp | CELL DIVISION CYCLEPROTEIN 123 (Schizosaccharomycespombe) |
PF07065(D123) | 4 | LEU A 123LEU A 43PRO A 102VAL A 132 | None | 1.10A | 2dqyC-4zgpA:undetectable | 2dqyC-4zgpA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgp | CELL DIVISION CYCLEPROTEIN 123 (Schizosaccharomycespombe) |
PF07065(D123) | 4 | LEU A 163LEU A 161PRO A 102VAL A 132 | None | 1.12A | 2dqyC-4zgpA:undetectable | 2dqyC-4zgpA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgq | CELL DIVISION CYCLEPROTEIN 123 (Schizosaccharomycespombe) |
PF07065(D123) | 4 | LEU A 123LEU A 43PRO A 102VAL A 132 | None | 1.02A | 2dqyC-4zgqA:undetectable | 2dqyC-4zgqA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgq | CELL DIVISION CYCLEPROTEIN 123 (Schizosaccharomycespombe) |
PF07065(D123) | 4 | LEU A 163LEU A 161PRO A 102VAL A 132 | None | 1.08A | 2dqyC-4zgqA:undetectable | 2dqyC-4zgqA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxi | TYROCIDINESYNTHETASE 3 (Acinetobacterbaumannii) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 4 | LEU A 568LEU A 590PRO A 577VAL A 594 | None | 1.15A | 2dqyC-4zxiA:8.7 | 2dqyC-4zxiA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5du3 | PLASMA PROTEASE C1INHIBITOR (Homo sapiens) |
PF00079(Serpin) | 4 | LEU A 456LEU A 352PRO A 467VAL A 125 | None | 1.15A | 2dqyC-5du3A:undetectable | 2dqyC-5du3A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4v | NUCLEOPROTEIN,PHOSPHOPROTEIN (Measlesmorbillivirus) |
PF00973(Paramyxo_ncap)PF13825(Paramyxo_PNT) | 4 | LEU A 33LEU A 148PRO A 65VAL A 62 | None | 1.09A | 2dqyC-5e4vA:0.7 | 2dqyC-5e4vA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9a | BETA-GALACTOSIDASE (Rahnella sp. R3) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | LEU A 654LEU A 642PRO A 624VAL A 627 | None | 1.17A | 2dqyC-5e9aA:undetectable | 2dqyC-5e9aA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eb5 | HNL ISOENZYME 5 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 452LEU A 397PRO A 300VAL A 363 | None | 1.17A | 2dqyC-5eb5A:undetectable | 2dqyC-5eb5A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ez3 | ACYL-COADEHYDROGENASE (Brucellamelitensis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M) | 4 | LEU A 448LEU A 494PRO A 388VAL A 389 | None | 1.13A | 2dqyC-5ez3A:undetectable | 2dqyC-5ez3A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f56 | SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE (Deinococcusradiodurans) |
PF01368(DHH)PF02272(DHHA1) | 4 | LEU A 442LEU A 512PRO A 30VAL A 31 | None | 1.17A | 2dqyC-5f56A:undetectable | 2dqyC-5f56A:21.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fv4 | CARBOXYLIC ESTERHYDROLASE (Sus scrofa) |
PF00135(COesterase) | 6 | TRP A 339LEU A 349LYS A 395LEU A 399PRO A 442VAL A 445 | None | 0.83A | 2dqyC-5fv4A:66.5 | 2dqyC-5fv4A:79.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g52 | VP2 (Deformed wingvirus) |
PF00073(Rhv) | 4 | LEU B 231LEU B 89PRO B 104VAL B 103 | None | 1.20A | 2dqyC-5g52B:undetectable | 2dqyC-5g52B:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw4 | T-COMPLEX PROTEIN 1SUBUNIT GAMMA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 4 | LEU g 246LEU g 343PRO g 292VAL g 290 | None | 1.21A | 2dqyC-5gw4g:undetectable | 2dqyC-5gw4g:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gy3 | GLUCANASE (Klebsiellapneumoniae) |
PF01270(Glyco_hydro_8) | 4 | TRP A 326LEU A 324LEU A 61PRO A 308 | None | 0.98A | 2dqyC-5gy3A:undetectable | 2dqyC-5gy3A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5id6 | CPF1 (LachnospiraceaebacteriumND2006) |
no annotation | 4 | LEU A1014LEU A1047PRO A1153VAL A1154 | None | 1.13A | 2dqyC-5id6A:0.8 | 2dqyC-5id6A:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti1 | FUMARYLACETOACETATEHYDROLASE (Paraburkholderiaxenovorans) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 4 | LEU A 250LEU A 364PRO A 137VAL A 138 | None | 1.16A | 2dqyC-5ti1A:undetectable | 2dqyC-5ti1A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vef | SERINE/THREONINE-PROTEIN KINASE PAK 4 (Homo sapiens) |
no annotation | 4 | LEU A 535LYS A 546LEU A 549PRO A 532 | None | 1.21A | 2dqyC-5vefA:undetectable | 2dqyC-5vefA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykn | PROBABLELYSINE-SPECIFICDEMETHYLASE JMJ14 (Arabidopsisthaliana) |
no annotation | 4 | LEU A 76LEU A 390PRO A 414VAL A 412 | None | 1.02A | 2dqyC-5yknA:undetectable | 2dqyC-5yknA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zbb | - (-) |
no annotation | 4 | LEU A 111LEU A 99PRO A 17VAL A 20 | IOD A 608 ( 4.4A)NoneNoneNone | 1.20A | 2dqyC-5zbbA:undetectable | 2dqyC-5zbbA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bni | LYSINE--TRNA LIGASE (Cryptosporidiumparvum) |
no annotation | 4 | LEU A 333LEU A 524PRO A 429VAL A 460 | None | 1.10A | 2dqyC-6bniA:undetectable | 2dqyC-6bniA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d0s | TBC1 DOMAIN FAMILYMEMBER 22B (Homo sapiens) |
no annotation | 4 | TRP A 220LEU A 222LEU A 193VAL A 211 | None | 1.18A | 2dqyC-6d0sA:1.8 | 2dqyC-6d0sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eu2 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC3 (Saccharomycescerevisiae) |
no annotation | 4 | LEU O 487LEU O 296PRO O 479VAL O 478 | None | 1.19A | 2dqyC-6eu2O:undetectable | 2dqyC-6eu2O:undetectable |