SIMILAR PATTERNS OF AMINO ACIDS FOR 2D55_C_DVAC2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a5l | UREASE (ALPHASUBUNIT) (Klebsiellaaerogenes) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 3 | THR C 301PRO C 303PRO C 300 | None | 0.86A | 2d55C-1a5lC:undetectable | 2d55C-1a5lC:5.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ai1 | IGG1-KAPPA 59.1 FAB(HEAVY CHAIN) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | THR H 117PRO H 149PRO H 118 | None | 0.90A | 2d55C-1ai1H:undetectable | 2d55C-1ai1H:12.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1as4 | ANTICHYMOTRYPSIN (Homo sapiens) |
PF00079(Serpin) | 3 | THR B 389PRO B 391PRO B 369 | None | 0.77A | 2d55C-1as4B:undetectable | 2d55C-1as4B:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bjw | ASPARTATEAMINOTRANSFERASE (Thermusthermophilus) |
PF00155(Aminotran_1_2) | 3 | THR A 265PRO A 267PRO A 67 | None | 0.84A | 2d55C-1bjwA:undetectable | 2d55C-1bjwA:2.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgm | ADENOSINE KINASE (Toxoplasmagondii) |
PF00294(PfkB) | 3 | THR A 10PRO A 12PRO A 85 | None | 0.83A | 2d55C-1dgmA:undetectable | 2d55C-1dgmA:3.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 3 | THR B 303PRO B 305PRO B 302 | None | 0.85A | 2d55C-1e9yB:undetectable | 2d55C-1e9yB:2.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnf | FIBRONECTIN (Homo sapiens) |
PF00041(fn3) | 3 | THR A1157PRO A1155PRO A1237 | None | 0.78A | 2d55C-1fnfA:undetectable | 2d55C-1fnfA:3.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1icp | 12-OXOPHYTODIENOATEREDUCTASE 1 (Solanumlycopersicum) |
PF00724(Oxidored_FMN) | 3 | THR A 74PRO A 129PRO A 124 | None | 0.74A | 2d55C-1icpA:undetectable | 2d55C-1icpA:6.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ikf | IGG1-KAPPA R45-45-11FAB (HEAVY CHAIN) (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | THR H 130PRO H 160PRO H 131 | None | 0.89A | 2d55C-1ikfH:undetectable | 2d55C-1ikfH:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0h | NEOPULLULANASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 3 | THR A 280PRO A 282PRO A 284 | None | 0.85A | 2d55C-1j0hA:undetectable | 2d55C-1j0hA:1.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l3w | EP-CADHERIN (Xenopus laevis) |
PF00028(Cadherin) | 3 | THR A 63PRO A 65PRO A 18 | None | 0.90A | 2d55C-1l3wA:undetectable | 2d55C-1l3wA:4.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfd | N15 ALPHA-BETAT-CELL RECEPTOR (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | THR B 123PRO B 125PRO B 232 | None | 0.85A | 2d55C-1nfdB:undetectable | 2d55C-1nfdB:7.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1op2 | VENOM SERINEPROTEINASE (Deinagkistrodonacutus) |
PF00089(Trypsin) | 3 | THR A 245PRO A 245PRO A 92 | None | 0.78A | 2d55C-1op2A:undetectable | 2d55C-1op2A:4.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qmn | ALPHA-1-ANTICHYMOTRYPSIN (Homo sapiens) |
PF00079(Serpin) | 3 | THR A 393PRO A 395PRO A 373 | None | 0.79A | 2d55C-1qmnA:undetectable | 2d55C-1qmnA:2.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qoi | SNUCYP-20 (Homo sapiens) |
PF00160(Pro_isomerase) | 3 | THR A 159PRO A 161PRO A 165 | None | 0.84A | 2d55C-1qoiA:undetectable | 2d55C-1qoiA:8.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1smr | RENIN (Mus musculus) |
PF00026(Asp) | 3 | THR A 295PRO A 297PRO A 294 | None | 0.81A | 2d55C-1smrA:undetectable | 2d55C-1smrA:7.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujx | POLYNUCLEOTIDEKINASE3'-PHOSPHATASE (Mus musculus) |
no annotation | 3 | THR A 46PRO A 44PRO A 26 | None | 0.90A | 2d55C-1ujxA:undetectable | 2d55C-1ujxA:28.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1waq | GROWTH/DIFFERENTIATION FACTOR 5 (Homo sapiens) |
PF00019(TGF_beta) | 3 | THR A 80PRO A 77PRO A 81 | None | 0.85A | 2d55C-1waqA:undetectable | 2d55C-1waqA:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2coa | PROTEIN KINASE C, D2TYPE (Homo sapiens) |
PF00169(PH) | 3 | THR A 72PRO A 74PRO A 92 | None | 0.89A | 2d55C-2coaA:undetectable | 2d55C-2coaA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cw7 | ENDONUCLEASEPI-PKOII (Thermococcuskodakarensis) |
PF14528(LAGLIDADG_3)PF14890(Intein_splicing) | 3 | THR A 366PRO A 368PRO A 129 | None | 0.84A | 2d55C-2cw7A:undetectable | 2d55C-2cw7A:2.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dfv | PROBABLE L-THREONINE3-DEHYDROGENASE (Pyrococcushorikoshii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | THR A 11PRO A 13PRO A 62 | None | 0.84A | 2d55C-2dfvA:undetectable | 2d55C-2dfvA:4.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ece | 462AA LONGHYPOTHETICALSELENIUM-BINDINGPROTEIN (Sulfurisphaeratokodaii) |
PF05694(SBP56) | 3 | THR A 113PRO A 115PRO A 120 | None | 0.27A | 2d55C-2eceA:undetectable | 2d55C-2eceA:5.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g1s | RENIN (Homo sapiens) |
PF00026(Asp) | 3 | THR A 304PRO A 306PRO A 303 | None | 0.70A | 2d55C-2g1sA:undetectable | 2d55C-2g1sA:7.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2it4 | CARBONIC ANHYDRASE 1 (Homo sapiens) |
PF00194(Carb_anhydrase) | 3 | THR A 248PRO A 250PRO A 30 | None | 0.71A | 2d55C-2it4A:undetectable | 2d55C-2it4A:8.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jg2 | SERINEPALMITOYLTRANSFERASE (Sphingomonaspaucimobilis) |
PF00155(Aminotran_1_2) | 3 | THR A 382PRO A 380PRO A 383 | None | 0.87A | 2d55C-2jg2A:undetectable | 2d55C-2jg2A:2.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nwh | CARBOHYDRATE KINASE (Agrobacteriumfabrum) |
PF00294(PfkB) | 3 | THR A 84PRO A 59PRO A 82 | None | 0.89A | 2d55C-2nwhA:undetectable | 2d55C-2nwhA:2.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2omz | EPITHELIAL-CADHERIN (Homo sapiens) |
PF00028(Cadherin) | 3 | THR B 63PRO B 65PRO B 18 | None | 0.79A | 2d55C-2omzB:undetectable | 2d55C-2omzB:10.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2otn | DIAMINOPIMELATEEPIMERASE (Bacillusanthracis) |
PF01678(DAP_epimerase) | 3 | THR A 182PRO A 180PRO A 186 | None | 0.75A | 2d55C-2otnA:undetectable | 2d55C-2otnA:5.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q01 | URONATE ISOMERASE (Caulobactervibrioides) |
PF02614(UxaC) | 3 | THR A 19PRO A 17PRO A 14 | None | 0.82A | 2d55C-2q01A:undetectable | 2d55C-2q01A:2.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3r | 12-OXOPHYTODIENOATEREDUCTASE 1 (Arabidopsisthaliana) |
PF00724(Oxidored_FMN) | 3 | THR A 70PRO A 125PRO A 120 | None | 0.88A | 2d55C-2q3rA:undetectable | 2d55C-2q3rA:3.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r14 | MORPHINONE REDUCTASE (Pseudomonasputida) |
PF00724(Oxidored_FMN) | 3 | THR A 68PRO A 123PRO A 118 | None | 0.72A | 2d55C-2r14A:undetectable | 2d55C-2r14A:6.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r3s | UNCHARACTERIZEDPROTEIN (Nostocpunctiforme) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 3 | THR A 279PRO A 273PRO A 281 | None | 0.84A | 2d55C-2r3sA:undetectable | 2d55C-2r3sA:3.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w2j | CARBONICANHYDRASE-RELATEDPROTEIN (Homo sapiens) |
PF00194(Carb_anhydrase) | 3 | THR A 277PRO A 279PRO A 51 | GOL A 502 ( 4.4A)NoneNone | 0.76A | 2d55C-2w2jA:undetectable | 2d55C-2w2jA:4.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsj | P-COUMARIC ACIDDECARBOXYLASE (Lactobacillusplantarum) |
PF05870(PA_decarbox) | 3 | THR A 125PRO A 127PRO A 95 | None | 0.52A | 2d55C-2wsjA:undetectable | 2d55C-2wsjA:8.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsx | L-CARNITINE/GAMMA-BUTYROBETAINEANTIPORTER (Escherichiacoli) |
PF02028(BCCT) | 3 | THR A 118PRO A 120PRO A 125 | None | 0.89A | 2d55C-2wsxA:undetectable | 2d55C-2wsxA:2.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzf | GLUCOSYLTRANSFERASE (Legionellapneumophila) |
PF16849(Glyco_transf_88) | 3 | THR A 478PRO A 476PRO A 480 | None | 0.71A | 2d55C-2wzfA:undetectable | 2d55C-2wzfA:2.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzg | GLUCOSYLTRANSFERASE (Legionellapneumophila) |
PF16849(Glyco_transf_88) | 3 | THR A 478PRO A 476PRO A 480 | None | 0.70A | 2d55C-2wzgA:undetectable | 2d55C-2wzgA:2.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ycj | 5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE (Carboxydothermushydrogenoformans) |
PF00809(Pterin_bind) | 3 | THR A 156PRO A 192PRO A 154 | None | 0.75A | 2d55C-2ycjA:undetectable | 2d55C-2ycjA:5.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a1n | NDP-SUGAR EPIMERASE (Thermoplasmavolcanium) |
PF01370(Epimerase) | 3 | THR A 272PRO A 274PRO A 118 | None | 0.83A | 2d55C-3a1nA:undetectable | 2d55C-3a1nA:7.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3b | CASEIN KINASE IISUBUNIT ALPHA' (Homo sapiens) |
PF00069(Pkinase) | 3 | THR X 109PRO X 105PRO X 110 | None | 0.79A | 2d55C-3e3bX:undetectable | 2d55C-3e3bX:2.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqx | FIC DOMAINCONTAININGTRANSCRIPTIONALREGULATOR (Shewanellaoneidensis) |
PF02661(Fic)PF13784(Fic_N) | 3 | THR A 143PRO A 141PRO A 157 | None | 0.88A | 2d55C-3eqxA:undetectable | 2d55C-3eqxA:3.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ez1 | AMINOTRANSFERASEMOCR FAMILY (Deinococcusgeothermalis) |
PF12897(Aminotran_MocR) | 3 | THR A 376PRO A 378PRO A 131 | None | 0.78A | 2d55C-3ez1A:undetectable | 2d55C-3ez1A:9.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f1z | PUTATIVE NUCLEICACID-BINDINGLIPOPROTEIN (Klebsiellapneumoniae) |
PF12869(tRNA_anti-like) | 3 | THR A 143PRO A 145PRO A 61 | None | 0.75A | 2d55C-3f1zA:undetectable | 2d55C-3f1zA:7.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fe4 | CARBONIC ANHYDRASE 6 (Homo sapiens) |
PF00194(Carb_anhydrase) | 3 | THR A 266PRO A 268PRO A 49 | None | 0.84A | 2d55C-3fe4A:undetectable | 2d55C-3fe4A:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gfb | L-THREONINE3-DEHYDROGENASE (Thermococcuskodakarensis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | THR A 11PRO A 13PRO A 62 | None | 0.84A | 2d55C-3gfbA:undetectable | 2d55C-3gfbA:4.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hgo | 12-OXOPHYTODIENOATEREDUCTASE 3 (Solanumlycopersicum) |
PF00724(Oxidored_FMN) | 3 | THR A 70PRO A 125PRO A 120 | None | 0.81A | 2d55C-3hgoA:undetectable | 2d55C-3hgoA:4.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hz6 | XYLULOKINASE (Chromobacteriumviolaceum) |
PF00370(FGGY_N)PF02782(FGGY_C) | 3 | THR A 283PRO A 355PRO A 300 | NoneNoneXUL A 515 (-4.2A) | 0.82A | 2d55C-3hz6A:undetectable | 2d55C-3hz6A:2.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3la4 | UREASE (Canavaliaensiformis) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 3 | THR A 574PRO A 576PRO A 573 | None | 0.90A | 2d55C-3la4A:undetectable | 2d55C-3la4A:3.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3loy | COPPER AMINE OXIDASE (Ogataea angusta) |
PF01179(Cu_amine_oxid) | 3 | THR A 549PRO A 587PRO A 486 | None | 0.79A | 2d55C-3loyA:undetectable | 2d55C-3loyA:3.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lr2 | MAJOR AMPULLATESPIDROIN 1 (Euprosthenopsaustralis) |
PF16763(Spidroin_N) | 3 | THR A 11PRO A 13PRO A 63 | None | 0.84A | 2d55C-3lr2A:undetectable | 2d55C-3lr2A:7.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mtv | PAPAIN-LIKE CYSTEINEPROTEASE (Porcinereproductiveand respiratorysyndrome virus) |
PF05411(Peptidase_C32) | 3 | THR A 84PRO A 86PRO A 169 | None | 0.86A | 2d55C-3mtvA:undetectable | 2d55C-3mtvA:7.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nad | FERULATEDECARBOXYLASE (Bacilluspumilus) |
PF05870(PA_decarbox) | 3 | THR A 118PRO A 120PRO A 88 | None | 0.49A | 2d55C-3nadA:undetectable | 2d55C-3nadA:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oad | RENIN (Homo sapiens) |
PF00026(Asp) | 3 | THR B 309PRO B 311PRO B 308 | None | 0.82A | 2d55C-3oadB:undetectable | 2d55C-3oadB:6.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q2v | CADHERIN-1 (Mus musculus) |
PF00028(Cadherin) | 3 | THR A 63PRO A 65PRO A 18 | None | 0.79A | 2d55C-3q2vA:undetectable | 2d55C-3q2vA:3.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q5t | TCR N30 BETA (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | THR A 121PRO A 123PRO A 226 | None | 0.90A | 2d55C-3q5tA:undetectable | 2d55C-3q5tA:7.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgk | UREASE SUBUNIT BETA2 (Helicobactermustelae) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 3 | THR C 302PRO C 304PRO C 301 | None | 0.81A | 2d55C-3qgkC:undetectable | 2d55C-3qgkC:7.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rcz | SUMO-CONJUGATINGENZYME UBC9 (Schizosaccharomycespombe) |
PF00179(UQ_con) | 3 | THR B 70PRO B 72PRO B 105 | None | 0.85A | 2d55C-3rczB:undetectable | 2d55C-3rczB:7.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s69 | THROMBIN-LIKE ENZYMEDEFIBRASE (Gloydiussaxatilis) |
PF00089(Trypsin) | 3 | THR A 246PRO A 248PRO A 90 | None | 0.82A | 2d55C-3s69A:undetectable | 2d55C-3s69A:4.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsd | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Bacillusanthracis) |
PF00478(IMPDH)PF00571(CBS) | 3 | THR A 164PRO A 166PRO A 187 | None | 0.84A | 2d55C-3tsdA:undetectable | 2d55C-3tsdA:4.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3txa | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcusagalactiae) |
PF00092(VWA) | 3 | THR A 707PRO A 705PRO A 699 | None | 0.83A | 2d55C-3txaA:undetectable | 2d55C-3txaA:1.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4p | INTEGRIN ALPHA-4 (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 3 | THR A 40PRO A 52PRO A 39 | 15P A 612 (-3.4A)NoneNone | 0.86A | 2d55C-3v4pA:undetectable | 2d55C-3v4pA:1.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3waj | TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE (Archaeoglobusfulgidus) |
PF02516(STT3) | 3 | THR A 72PRO A 75PRO A 565 | None | 0.79A | 2d55C-3wajA:undetectable | 2d55C-3wajA:1.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3whp | PROBABLETRANSCRIPTIONALREGULATOR (Thermusthermophilus) |
PF02310(B12-binding)PF02607(B12-binding_2) | 3 | THR A 202PRO A 200PRO A 173 | None | 0.90A | 2d55C-3whpA:undetectable | 2d55C-3whpA:4.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zx9 | CAPSID PROTEIN (Turnip crinklevirus) |
PF00729(Viral_coat) | 3 | THR A 182PRO A 180PRO A 140 | None | 0.82A | 2d55C-3zx9A:undetectable | 2d55C-3zx9A:4.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4alb | PHENOLIC ACIDDECARBOXYLASE PADC (Bacillussubtilis) |
PF05870(PA_decarbox) | 3 | THR A 118PRO A 120PRO A 88 | None | 0.56A | 2d55C-4albA:undetectable | 2d55C-4albA:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b2n | 70 KDA PROTEIN (Xanthomonas sp.35Y) |
no annotation | 3 | THR A 512PRO A 514PRO A 212 | None | 0.90A | 2d55C-4b2nA:undetectable | 2d55C-4b2nA:1.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bb9 | GLUCOKINASEREGULATORY PROTEIN (Homo sapiens) |
no annotation | 3 | THR A 31PRO A 251PRO A 29 | None | 0.89A | 2d55C-4bb9A:undetectable | 2d55C-4bb9A:1.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1n | KPAGO (Vanderwaltozymapolyspora) |
PF02171(Piwi) | 3 | THR A 869PRO A 871PRO A 834 | None | 0.65A | 2d55C-4f1nA:undetectable | 2d55C-4f1nA:1.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fi9 | SUNDOMAIN-CONTAININGPROTEIN 2 (Homo sapiens) |
PF07738(Sad1_UNC) | 3 | THR A 696PRO A 643PRO A 607 | None | 0.71A | 2d55C-4fi9A:undetectable | 2d55C-4fi9A:7.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g7e | UREASE (Cajanus cajan) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 3 | THR B 574PRO B 576PRO B 573 | None | 0.89A | 2d55C-4g7eB:undetectable | 2d55C-4g7eB:3.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hxy | PLM1 (Streptomycessp. HK803) |
PF08659(KR) | 3 | THR A 79PRO A 81PRO A 54 | None | 0.81A | 2d55C-4hxyA:undetectable | 2d55C-4hxyA:9.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k2x | POLYKETIDEOXYGENASE/HYDROXYLASE (Streptomycesrimosus) |
PF01494(FAD_binding_3) | 3 | THR A 138PRO A 140PRO A 143 | None | 0.89A | 2d55C-4k2xA:undetectable | 2d55C-4k2xA:2.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n2z | GH62ARABINOFURANOSIDASE (Podosporaanserina) |
PF03664(Glyco_hydro_62) | 3 | THR A 140PRO A 142PRO A 96 | None | 0.72A | 2d55C-4n2zA:undetectable | 2d55C-4n2zA:5.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n7t | PHOSPHOPENTOMUTASE (Streptococcusmutans) |
PF01676(Metalloenzyme) | 3 | THR A 81PRO A 357PRO A 62 | NoneNoneGOL A 505 (-4.8A) | 0.76A | 2d55C-4n7tA:undetectable | 2d55C-4n7tA:3.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvi | GH62 HYDROLASE (Mycothermusthermophilus) |
PF03664(Glyco_hydro_62) | 3 | THR A 146PRO A 148PRO A 102 | NonePO4 A 602 ( 4.5A)None | 0.71A | 2d55C-4pviA:undetectable | 2d55C-4pviA:2.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q4y | COXSACKIEVIRUSCAPSID PROTEIN VP1COXSACKIEVIRUSCAPSID PROTEIN VP4 (Enterovirus C;Enterovirus C) |
PF00073(Rhv)PF02226(Pico_P1A) | 3 | THR 4 64PRO 4 66PRO 1 42 | None | 0.89A | 2d55C-4q4y4:undetectable | 2d55C-4q4y4:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ra7 | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Atopobiumparvulum) |
PF00905(Transpeptidase) | 3 | THR A 640PRO A 830PRO A 849 | None | 0.90A | 2d55C-4ra7A:undetectable | 2d55C-4ra7A:3.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 3 | THR A 777PRO A 779PRO A 781 | None | 0.86A | 2d55C-4wd9A:undetectable | 2d55C-4wd9A:3.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x5l | DOWN SYNDROME CELLADHESION MOLECULE,ISOFORM AM (Drosophilamelanogaster) |
PF13927(Ig_3) | 3 | THR A 82PRO A 84PRO A 3 | None | 0.89A | 2d55C-4x5lA:undetectable | 2d55C-4x5lA:9.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 3 | THR A 213PRO A 215PRO A 31 | None | 0.82A | 2d55C-4x5sA:undetectable | 2d55C-4x5sA:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yfg | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE DELTA (Mus musculus) |
no annotation | 3 | THR B 29PRO B 58PRO B 30 | None | 0.82A | 2d55C-4yfgB:undetectable | 2d55C-4yfgB:5.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yh7 | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE DELTA (Mus musculus) |
PF00041(fn3)PF07679(I-set)PF13927(Ig_3) | 3 | THR A 29PRO A 58PRO A 30 | None | 0.83A | 2d55C-4yh7A:undetectable | 2d55C-4yh7A:2.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z42 | UREASE SUBUNIT ALPHA (Yersiniaenterocolitica) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 3 | THR C 306PRO C 308PRO C 305 | None | 0.89A | 2d55C-4z42C:undetectable | 2d55C-4z42C:3.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ztu | DNA POLYMERASESUBUNIT GAMMA-2,MITOCHONDRIAL (Homo sapiens) |
PF03129(HGTP_anticodon) | 3 | THR B 243PRO B 333PRO B 205 | None | 0.79A | 2d55C-4ztuB:undetectable | 2d55C-4ztuB:1.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a29 | EXOPOLYGALACTURONATELYASE (Vibriovulnificus) |
PF06917(Pectate_lyase_2) | 3 | THR A 282PRO A 284PRO A 222 | None | 0.89A | 2d55C-5a29A:undetectable | 2d55C-5a29A:1.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b6t | GLYCOSYL HYDROLASEFAMILY 62 PROTEIN (Coprinopsiscinerea) |
PF03664(Glyco_hydro_62) | 3 | THR A 200PRO A 202PRO A 156 | None | 0.74A | 2d55C-5b6tA:undetectable | 2d55C-5b6tA:3.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c53 | POL GAMMA B (Homo sapiens) |
PF03129(HGTP_anticodon) | 3 | THR B 243PRO B 333PRO B 205 | None | 0.76A | 2d55C-5c53B:undetectable | 2d55C-5c53B:1.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dv5 | GNTR FAMILYTRANSCRIPTIONALREGULATOR (Vibrioalginolyticus) |
PF00392(GntR)PF07840(FadR_C) | 3 | THR A 272PRO A 8PRO A 271 | None | 0.87A | 2d55C-5dv5A:undetectable | 2d55C-5dv5A:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ed8 | MKIAA0668 PROTEIN (Mus musculus) |
PF07738(Sad1_UNC) | 3 | THR A 678PRO A 625PRO A 589 | None | 0.80A | 2d55C-5ed8A:undetectable | 2d55C-5ed8A:5.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1i | PLECTIN (Homo sapiens) |
no annotation | 3 | THR A1148PRO A1146PRO A1150 | None | 0.81A | 2d55C-5j1iA:undetectable | 2d55C-5j1iA:4.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jow | NON-REDUCING ENDALPHA-L-ARABINOFURANOSIDASE BOGH43A (Bacteroidesovatus) |
PF04616(Glyco_hydro_43) | 3 | THR A 76PRO A 78PRO A 55 | None | 0.90A | 2d55C-5jowA:undetectable | 2d55C-5jowA:2.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k21 | PYOCYANINDEMETHYLASE (Mycolicibacteriumfortuitum) |
no annotation | 3 | THR A 94PRO A 98PRO A 95 | None | 0.89A | 2d55C-5k21A:undetectable | 2d55C-5k21A:6.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mlg | RENIN (Rattusnorvegicus) |
no annotation | 3 | THR A 350PRO A 352PRO A 349 | None | 0.87A | 2d55C-5mlgA:undetectable | 2d55C-5mlgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ntf | AMINOPEPTIDASE (Trypanosomacruzi) |
PF00883(Peptidase_M17) | 3 | THR A 148PRO A 191PRO A 188 | None | 0.90A | 2d55C-5ntfA:undetectable | 2d55C-5ntfA:1.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o82 | INTRACELLULAREXO-ALPHA-(1->5)-L-ARABINOFURANOSIDASE (Chaetomiumthermophilum) |
no annotation | 3 | THR A 220PRO A 222PRO A 219 | None | 0.88A | 2d55C-5o82A:undetectable | 2d55C-5o82A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5the | UNCHARACTERIZEDPROTEIN (Vanderwaltozymapolyspora) |
no annotation | 3 | THR A 869PRO A 871PRO A 834 | None | 0.69A | 2d55C-5theA:undetectable | 2d55C-5theA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uld | TRANSPORTER, NADCFAMILY (Vibrio cholerae) |
PF00939(Na_sulph_symp) | 3 | THR A 421PRO A 418PRO A 423 | CIT A 503 (-3.1A)NoneNone | 0.74A | 2d55C-5uldA:undetectable | 2d55C-5uldA:8.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v0r | UBIQUITIN-CONJUGATING ENZYME (Naegleriafowleri) |
PF00179(UQ_con) | 3 | THR A 76PRO A 78PRO A 109 | None | 0.90A | 2d55C-5v0rA:undetectable | 2d55C-5v0rA:6.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfa | NAD-REDUCINGHYDROGENASE (Hydrogenophilusthermoluteolus) |
PF01257(2Fe-2S_thioredx)PF01512(Complex1_51K)PF10589(NADH_4Fe-4S) | 3 | THR A 342PRO A 340PRO A 349 | None | 0.77A | 2d55C-5xfaA:undetectable | 2d55C-5xfaA:2.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fe1 | CARBONIC ANHYDRASE 9 (Homo sapiens) |
no annotation | 3 | THR A 248PRO A 250PRO A 30 | None | 0.72A | 2d55C-6fe1A:undetectable | 2d55C-6fe1A:undetectable |