SIMILAR PATTERNS OF AMINO ACIDS FOR 2CML_A_ZMRA1478

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0j TRYPSIN

(Salmo salar)
PF00089
(Trypsin)
4 SER A 145
SER A 147
SER A 148
ASN A 150
None
1.10A 2cmlA-1a0jA:
undetectable
2cmlA-1a0jA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cvm PHYTASE

(Bacillus
amyloliquefaciens)
PF02333
(Phytase)
4 SER A 283
ASP A 298
SER A 278
ASN A 281
None
1.14A 2cmlA-1cvmA:
8.0
2cmlA-1cvmA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fs2 SKP2

(Homo sapiens)
PF12937
(F-box-like)
4 SER A 303
ASP A 331
SER A 276
ASN A 301
None
1.15A 2cmlA-1fs2A:
undetectable
2cmlA-1fs2A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis)
PF12468
(TTSSLRR)
4 SER A1305
SER A1306
SER A1285
ASN A1303
None
1.11A 2cmlA-1jl5A:
undetectable
2cmlA-1jl5A:
20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nmb N9 NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
4 SER N 367
SER N 370
SER N 372
TRP N 403
None
0.57A 2cmlA-1nmbN:
70.8
2cmlA-1nmbN:
68.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tj5 SUCROSE-PHOSPHATASE

(Synechocystis
sp. PCC 6803)
PF05116
(S6PP)
4 SER A 150
ASP A 153
SER A 149
SER A 187
SUC  A 245 ( 4.6A)
SUC  A 245 ( 4.0A)
SUC  A 245 (-3.6A)
MG  A 247 (-2.6A)
1.14A 2cmlA-1tj5A:
undetectable
2cmlA-1tj5A:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1v0z NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
7 SER A 374
ASP A 376
SER A 377
SER A 379
ASN A 406
GLN A 407
TRP A 409
None
0.15A 2cmlA-1v0zA:
76.8
2cmlA-1v0zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1xog NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
5 SER A 368
SER A 371
SER A 373
ASN A 400
TRP A 403
None
0.66A 2cmlA-1xogA:
71.6
2cmlA-1xogA:
69.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zb1 BRO1 PROTEIN

(Saccharomyces
cerevisiae)
PF03097
(BRO1)
4 SER A 166
ASP A 168
SER A 164
GLN A 110
None
1.15A 2cmlA-1zb1A:
undetectable
2cmlA-1zb1A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlp PETAL DEATH PROTEIN

(Dianthus
caryophyllus)
PF13714
(PEP_mutase)
4 ASP A 107
SER A  66
SER A 257
ASN A 231
MG  A 401 (-2.7A)
None
GAQ  A 402 ( 3.8A)
GAQ  A 402 (-3.9A)
1.12A 2cmlA-1zlpA:
undetectable
2cmlA-1zlpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ass S-PHASE
KINASE-ASSOCIATED
PROTEIN 2


(Homo sapiens)
PF12937
(F-box-like)
4 SER B2291
ASP B2319
SER B2264
ASN B2289
None
1.09A 2cmlA-2assB:
undetectable
2cmlA-2assB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ass S-PHASE
KINASE-ASSOCIATED
PROTEIN 2


(Homo sapiens)
PF12937
(F-box-like)
4 SER B2318
ASP B2316
SER B2341
SER B2343
None
1.06A 2cmlA-2assB:
undetectable
2cmlA-2assB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN


(Cryptosporidium
parvum)
PF08603
(CAP_C)
4 SER A 111
SER A 112
SER A  93
ASN A  92
None
1.15A 2cmlA-2b0rA:
undetectable
2cmlA-2b0rA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gk3 PUTATIVE CYTOPLASMIC
PROTEIN


(Salmonella
enterica)
PF07090
(GATase1_like)
4 SER A 126
ASP A  82
SER A  81
ASN A 187
None
GOL  A1001 (-3.4A)
None
None
1.10A 2cmlA-2gk3A:
undetectable
2cmlA-2gk3A:
20.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2htv NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
5 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
None
0.37A 2cmlA-2htvA:
63.0
2cmlA-2htvA:
45.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m26 HCF C-TERMINAL CHAIN
1


(Mus musculus)
no annotation 4 SER A  83
ASP A 122
SER A 123
SER A  79
None
1.08A 2cmlA-2m26A:
undetectable
2cmlA-2m26A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mjm PROTEIN NLRC5

(Mus musculus)
no annotation 4 SER A  10
ASP A   7
SER A  96
TRP A  98
None
1.13A 2cmlA-2mjmA:
undetectable
2cmlA-2mjmA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nmp CYSTATHIONINE
GAMMA-LYASE


(Homo sapiens)
PF01053
(Cys_Met_Meta_PP)
4 SER A 226
SER A 206
ASN A 188
GLN A 196
None
1.12A 2cmlA-2nmpA:
undetectable
2cmlA-2nmpA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2no5 (S)-2-HALOACID
DEHALOGENASE IVA


(Burkholderia
cepacia)
PF13419
(HAD_2)
4 SER A 215
ASP A 100
SER A 217
ASN A 214
SO4  A1006 ( 2.8A)
SO4  A1006 ( 3.7A)
SO4  A1006 ( 4.4A)
None
1.11A 2cmlA-2no5A:
undetectable
2cmlA-2no5A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odl ADHESIN

(Haemophilus
influenzae)
PF05860
(Haemagg_act)
4 ASP A 294
SER A 290
ASN A 318
GLN A 319
None
0.98A 2cmlA-2odlA:
undetectable
2cmlA-2odlA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9n ACTIN-RELATED
PROTEIN 2/3 COMPLEX
SUBUNIT 1B


(Bos taurus)
PF00400
(WD40)
4 SER C 215
ASP C 230
SER C 211
ASN C 213
None
1.11A 2cmlA-2p9nC:
11.4
2cmlA-2p9nC:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v2t TRANSCRIPTION FACTOR
RELB


(Mus musculus)
PF00554
(RHD_DNA_bind)
PF16179
(RHD_dimer)
4 ASP A 240
SER A 275
ASN A 277
GLN A 307
None
1.00A 2cmlA-2v2tA:
undetectable
2cmlA-2v2tA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6g PROGESTERONE
5-BETA-REDUCTASE


(Digitalis
lanata)
PF01370
(Epimerase)
4 SER A 251
ASP A 249
SER A 277
GLN A 143
None
None
None
NAP  A1390 (-3.9A)
1.14A 2cmlA-2v6gA:
undetectable
2cmlA-2v6gA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7g UROCANATE HYDRATASE

(Pseudomonas
putida)
PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C)
5 SER A 237
ASP A 213
SER A 193
ASN A 195
GLN A 182
None
1.42A 2cmlA-2v7gA:
undetectable
2cmlA-2v7gA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x7j 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE
-1-CARBOXYLATE
SYNTHASE


(Bacillus
subtilis)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
PF16582
(TPP_enzyme_M_2)
4 ASP A 252
SER A 255
ASN A 259
GLN A 418
None
1.11A 2cmlA-2x7jA:
undetectable
2cmlA-2x7jA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yjq CEL44C

(Paenibacillus
polymyxa)
PF12891
(Glyco_hydro_44)
4 SER A 455
ASP A 457
SER A 458
ASN A 432
None
0.87A 2cmlA-2yjqA:
undetectable
2cmlA-2yjqA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5c PROTEIN YPL144W
UNCHARACTERIZED
PROTEIN YLR021W


(Saccharomyces
cerevisiae)
PF10448
(POC3_POC4)
4 SER A  57
SER A 118
SER A  55
ASN B  36
None
1.09A 2cmlA-2z5cA:
undetectable
2cmlA-2z5cA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
1, VARIABLE
LYMPHOCYTE RECEPTOR
B


(Eptatretus
burgeri;
Homo sapiens)
PF11921
(DUF3439)
PF13855
(LRR_8)
4 SER B 431
SER B 432
SER B 406
ASN B 429
NAG  A 831 (-3.6A)
NAG  A 833 ( 3.9A)
NAG  A 831 (-3.0A)
NAG  A 831 (-1.8A)
1.06A 2cmlA-2z7xB:
undetectable
2cmlA-2z7xB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B


(Eptatretus
burgeri;
Homo sapiens)
PF11921
(DUF3439)
PF13855
(LRR_8)
4 SER A 444
SER A 445
SER A 421
ASN A 442
NAG  A 921 ( 4.4A)
None
NAG  A 921 (-2.5A)
NAG  A 921 (-1.8A)
0.96A 2cmlA-2z7xA:
undetectable
2cmlA-2z7xA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z81 TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B


(Eptatretus
burgeri;
Mus musculus)
PF11921
(DUF3439)
PF13306
(LRR_5)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 SER A 444
SER A 445
SER A 421
ASN A 442
NAG  A 811 ( 4.3A)
None
NAG  A 811 (-3.4A)
NAG  A 811 (-1.8A)
1.02A 2cmlA-2z81A:
undetectable
2cmlA-2z81A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B


(Eptatretus
burgeri;
Mus musculus)
PF11921
(DUF3439)
PF13855
(LRR_8)
4 SER B 436
SER B 437
SER B 411
ASN B 434
NDG  B 971 (-3.6A)
NAG  B 972 ( 4.2A)
NDG  B 971 (-2.7A)
NDG  B 971 (-2.1A)
1.02A 2cmlA-3a79B:
undetectable
2cmlA-3a79B:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzw PUTATIVE LIPASE

(Bacteroides
thetaiotaomicron)
PF13472
(Lipase_GDSL_2)
4 ASP A 203
SER A 191
ASN A 242
GLN A 248
None
1.00A 2cmlA-3bzwA:
undetectable
2cmlA-3bzwA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehm SUSD HOMOLOG

(Bacteroides
thetaiotaomicron)
PF12741
(SusD-like)
5 SER A 242
ASP A 239
SER A 241
ASN A 197
GLN A 196
None
1.47A 2cmlA-3ehmA:
undetectable
2cmlA-3ehmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE


(Sulfolobus
solfataricus)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
4 ASP A 268
SER A 265
SER A 116
ASN A  89
None
None
None
PRP  A 401 (-4.1A)
0.88A 2cmlA-3gbrA:
undetectable
2cmlA-3gbrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gm8 GLYCOSIDE HYDROLASE
FAMILY 2, CANDIDATE
BETA-GLYCOSIDASE


(Bacteroides
vulgatus)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982)
4 SER A 255
ASP A 257
SER A 258
ASN A 298
None
0.99A 2cmlA-3gm8A:
undetectable
2cmlA-3gm8A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0d CTSR

(Geobacillus
stearothermophilus)
PF05848
(CtsR)
4 SER A  96
ASP A 100
SER A  97
SER A  94
None
1.12A 2cmlA-3h0dA:
undetectable
2cmlA-3h0dA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j70 ENVELOPE
GLYCOPROTEIN GP120


(Human
immunodeficiency
virus 1)
PF00516
(GP120)
4 SER D 405
ASN D 340
GLN D 344
TRP D 395
None
0.95A 2cmlA-3j70D:
undetectable
2cmlA-3j70D:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ll3 GLUCONATE KINASE

(Lactobacillus
acidophilus)
PF00370
(FGGY_N)
PF02782
(FGGY_C)
4 SER A 241
ASP A 237
SER A 427
GLN A 425
None
XUL  A7778 (-2.9A)
None
None
1.07A 2cmlA-3ll3A:
undetectable
2cmlA-3ll3A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE


(Parabacteroides
distasonis)
PF02769
(AIRS_C)
4 SER A 190
SER A 189
ASN A 335
GLN A 292
None
None
CL  A 394 (-3.9A)
None
1.08A 2cmlA-3mdoA:
undetectable
2cmlA-3mdoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvq SEMAPHORIN-7A

(Homo sapiens)
PF01403
(Sema)
PF01437
(PSI)
PF13895
(Ig_2)
4 SER A  85
ASP A  99
SER A  86
SER A  84
None
1.14A 2cmlA-3nvqA:
4.2
2cmlA-3nvqA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja LEUCINE-RICH IMMUNE
MOLECULE 1


(Anopheles
gambiae)
PF00560
(LRR_1)
4 SER A  88
SER A  89
SER A  64
ASN A  86
NAG  A1001 ( 4.4A)
None
NAG  A1001 (-3.1A)
NAG  A1001 (-1.8A)
1.09A 2cmlA-3ojaA:
undetectable
2cmlA-3ojaA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL-COENZYME M
REDUCTASE, BETA
SUBUNIT


(uncultured
archaeon)
PF02241
(MCR_beta)
PF02783
(MCR_beta_N)
4 SER B 356
SER B 355
SER B 359
GLN B 321
None
1.03A 2cmlA-3sqgB:
undetectable
2cmlA-3sqgB:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1e HEMAGGLUTININ-NEURAM
INIDASE


(Avian
avulavirus 1)
PF00423
(HN)
4 SER A 517
SER A 518
SER A 519
ASN A 549
None
1.05A 2cmlA-3t1eA:
21.6
2cmlA-3t1eA:
21.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ti8 NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
4 SER A 367
SER A 372
ASN A 400
TRP A 403
None
0.14A 2cmlA-3ti8A:
64.9
2cmlA-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tia NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
5 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
None
0.73A 2cmlA-3tiaA:
64.9
2cmlA-3tiaA:
43.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1s FAB PGT145 HEAVY
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 SER H  76
ASP H  72
SER H  73
ASN H  27
None
1.13A 2cmlA-3u1sH:
undetectable
2cmlA-3u1sH:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3whs GAMMA-GLUTAMYLTRANSP
EPTIDASE SMALL CHAIN


(Bacillus
subtilis)
PF01019
(G_glu_transpept)
4 SER B 520
SER B 522
SER B 523
ASN B 519
None
1.07A 2cmlA-3whsB:
undetectable
2cmlA-3whsB:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 SER A 148
SER A 150
SER A 130
ASN A 128
None
0.91A 2cmlA-3wpeA:
undetectable
2cmlA-3wpeA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aw7 GH86A
BETA-PORPHYRANASE


(Bacteroides
plebeius)
no annotation 4 ASP A 238
SER A 303
SER A 302
ASN A 460
None
1.11A 2cmlA-4aw7A:
undetectable
2cmlA-4aw7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awe ENDO-BETA-D-1,4-MANN
ANASE


(Neurospora
sitophila)
PF00150
(Cellulase)
4 SER A 289
ASP A 252
GLN A 281
TRP A 282
None
1.13A 2cmlA-4aweA:
undetectable
2cmlA-4aweA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bjj TRANSCRIPTION FACTOR
TAU SUBUNIT SFC1


(Schizosaccharomyces
pombe)
PF09734
(Tau95)
4 SER A   7
ASP A   8
SER A  91
ASN A  89
None
0.98A 2cmlA-4bjjA:
undetectable
2cmlA-4bjjA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6o METACASPASE-1

(Saccharomyces
cerevisiae)
PF00656
(Peptidase_C14)
4 ASP A 158
SER A 218
ASN A 144
GLN A 151
None
1.09A 2cmlA-4f6oA:
undetectable
2cmlA-4f6oA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gji L-RHAMNOSE ISOMERASE

(Pseudomonas
stutzeri)
no annotation 4 ASP A 124
SER A  99
GLN A 328
TRP A  57
None
None
None
RNS  A1001 (-3.5A)
0.95A 2cmlA-4gjiA:
undetectable
2cmlA-4gjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gos V-SET
DOMAIN-CONTAINING
T-CELL ACTIVATION
INHIBITOR 1


(Homo sapiens)
PF07686
(V-set)
4 SER A  55
SER A 114
ASN A 112
GLN A 107
NAG  A 202 ( 4.5A)
NAG  A 201 (-3.2A)
NAG  A 201 (-1.9A)
NAG  A 201 (-4.7A)
1.06A 2cmlA-4gosA:
undetectable
2cmlA-4gosA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gwn MEPRIN A SUBUNIT
BETA


(Homo sapiens)
PF00629
(MAM)
PF01400
(Astacin)
4 SER A 242
ASP A 204
SER A 244
GLN A 151
None
1.08A 2cmlA-4gwnA:
undetectable
2cmlA-4gwnA:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4h53 NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
5 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
SIA  A 510 (-2.5A)
SIA  A 510 (-2.6A)
SIA  A 510 (-2.8A)
SIA  A 510 (-3.4A)
SIA  A 510 (-3.5A)
0.72A 2cmlA-4h53A:
64.8
2cmlA-4h53A:
51.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hcr PF-547659 HEAVY
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 SER H 104
ASP H 106
SER H 102
SER H 103
None
1.10A 2cmlA-4hcrH:
undetectable
2cmlA-4hcrH:
19.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hzz NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
4 SER A 367
SER A 372
ASN A 400
TRP A 403
None
0.23A 2cmlA-4hzzA:
63.0
2cmlA-4hzzA:
50.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4io1 RIBOSE-5-PHOSPHATE
ISOMERASE A


(Francisella
tularensis)
PF06026
(Rib_5-P_isom_A)
4 SER A  59
ASP A  61
SER A  62
SER A  58
None
1.14A 2cmlA-4io1A:
undetectable
2cmlA-4io1A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae)
PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5)
4 SER A 464
SER A 442
SER A 440
ASN A 466
None
1.05A 2cmlA-4iugA:
undetectable
2cmlA-4iugA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4izx RICIN B-LIKE LECTIN

(Macrolepiota
procera)
PF14200
(RicinB_lectin_2)
4 SER A  60
SER A  62
SER A  57
TRP A  44
None
0.92A 2cmlA-4izxA:
undetectable
2cmlA-4izxA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1


(Arabidopsis
thaliana)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 SER A 159
SER A 134
SER A 133
ASN A 157
NAG  A 811 (-3.5A)
NAG  A 811 (-3.2A)
NAG  A 811 (-3.4A)
NAG  A 811 (-1.8A)
1.14A 2cmlA-4j0mA:
undetectable
2cmlA-4j0mA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kfz ANTI-LMO2 VH

(Homo sapiens)
PF07686
(V-set)
4 SER C  56
SER C  57
SER C  52
ASN C  54
None
1.06A 2cmlA-4kfzC:
undetectable
2cmlA-4kfzC:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m69 MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN


(Mus musculus)
PF07714
(Pkinase_Tyr)
4 SER B 320
SER B 322
SER B 323
ASN B 318
None
1.06A 2cmlA-4m69B:
undetectable
2cmlA-4m69B:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 SER A 156
SER A 157
SER A 130
ASN A 154
NAG  A 801 (-3.5A)
NAG  A 802 ( 3.8A)
NAG  A 801 (-3.3A)
NAG  A 801 (-1.8A)
1.08A 2cmlA-4m7eA:
undetectable
2cmlA-4m7eA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 SER A 277
SER A 278
SER A 253
ASN A 275
NAG  A 803 (-3.1A)
NAG  A 804 ( 4.1A)
NAG  A 803 (-2.3A)
NAG  A 803 (-1.7A)
1.04A 2cmlA-4m7eA:
undetectable
2cmlA-4m7eA:
19.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4mju NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
5 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
None
0.30A 2cmlA-4mjuA:
62.7
2cmlA-4mjuA:
48.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzu 13PL LIGHT CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 SER H  55
SER H  56
SER H  52
ASN H  53
None
1.02A 2cmlA-4nzuH:
undetectable
2cmlA-4nzuH:
20.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qn3 NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
5 SER A 286
SER A 289
SER A 291
ASN A 318
TRP A 321
None
0.25A 2cmlA-4qn3A:
72.3
2cmlA-4qn3A:
61.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r40 PROTEIN TOLB

(Yersinia pestis)
PF04052
(TolB_N)
PF07676
(PD40)
4 SER A 288
SER A 306
ASN A 269
GLN A 282
FMT  A 502 (-3.3A)
None
None
None
1.12A 2cmlA-4r40A:
7.6
2cmlA-4r40A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4z PNGF-II

(Elizabethkingia
meningoseptica)
PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C)
4 SER A 471
SER A 481
SER A 479
ASN A 473
None
1.07A 2cmlA-4r4zA:
undetectable
2cmlA-4r4zA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r6f LEUCINE RICH REPEAT
DLRR_I


(synthetic
construct)
PF12354
(Internalin_N)
PF13855
(LRR_8)
4 SER A 196
SER A 197
SER A 164
ASN A 194
None
1.08A 2cmlA-4r6fA:
undetectable
2cmlA-4r6fA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r6f LEUCINE RICH REPEAT
DLRR_I


(synthetic
construct)
PF12354
(Internalin_N)
PF13855
(LRR_8)
4 SER A 276
SER A 277
SER A 244
ASN A 274
None
1.11A 2cmlA-4r6fA:
undetectable
2cmlA-4r6fA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcj YTH
DOMAIN-CONTAINING
FAMILY PROTEIN 1


(Homo sapiens)
PF04146
(YTH)
4 SER A 398
ASP A 400
SER A 396
TRP A 411
None
1.15A 2cmlA-4rcjA:
undetectable
2cmlA-4rcjA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1y ATRAZINE
CHLOROHYDROLASE


(Pseudomonas sp.
ADP)
PF01979
(Amidohydro_1)
4 SER A 301
ASP A 327
SER A 331
GLN A  83
None
FE  A 481 (-2.8A)
None
None
1.05A 2cmlA-4v1yA:
undetectable
2cmlA-4v1yA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb6 ALPHA-D-RIBOSE
1-METHYLPHOSPHONATE
5-TRIPHOSPHATE
SYNTHASE SUBUNIT
PHNI


(Escherichia
coli)
PF05861
(PhnI)
4 SER C 190
ASP C 176
SER C 191
GLN C 295
None
1.12A 2cmlA-4xb6C:
undetectable
2cmlA-4xb6C:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4v CONSERVED
HYPOTHETICAL
SECRETED PROTEIN


(Helicobacter
pylori)
PF03734
(YkuD)
4 SER A 274
ASP A 294
SER A 273
ASN A  66
None
0.96A 2cmlA-4y4vA:
undetectable
2cmlA-4y4vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhc STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN


(Schizosaccharomyces
pombe)
no annotation 4 SER A 838
SER A 850
SER A 851
GLN A1003
None
0.97A 2cmlA-4yhcA:
7.7
2cmlA-4yhcA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2e T-CELL
DIFFERENTIATION
ANTIGEN CD6


(Homo sapiens)
PF00530
(SRCR)
4 SER A  55
SER A  51
SER A  52
TRP A 238
None
1.04A 2cmlA-5a2eA:
undetectable
2cmlA-5a2eA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5brr TISSUE-TYPE
PLASMINOGEN
ACTIVATOR


(Homo sapiens)
PF00089
(Trypsin)
4 SER E 110
ASP E 110
SER E 110
GLN E  81
None
1.12A 2cmlA-5brrE:
undetectable
2cmlA-5brrE:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5diz PROTEINACEOUS RNASE
P 2


(Arabidopsis
thaliana)
PF16953
(PRORP)
PF17177
(PPR_long)
4 SER A 114
SER A 111
ASN A 108
GLN A  66
None
1.14A 2cmlA-5dizA:
undetectable
2cmlA-5dizA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e0q ANTI-NUP98 NANOBODY
TP377
NUCLEAR PORE COMPLEX
PROTEIN NUP98-NUP96


(Vicugna pacos;
Xenopus
tropicalis)
PF04096
(Nucleoporin2)
PF07686
(V-set)
4 ASP B 775
SER B 776
SER A  57
ASN A  54
None
1.07A 2cmlA-5e0qB:
undetectable
2cmlA-5e0qB:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejy MYOSIN-I HEAVY CHAIN

(Dictyostelium
discoideum)
PF00784
(MyTH4)
4 SER A 276
SER A 263
SER A 267
ASN A 279
None
0.97A 2cmlA-5ejyA:
undetectable
2cmlA-5ejyA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA


(Pseudomonas
aeruginosa)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 ASP A 615
SER A 582
SER A 584
GLN A  33
None
1.04A 2cmlA-5fp2A:
undetectable
2cmlA-5fp2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghs SSDNA-SPECIFIC
EXONUCLEASE


(Thermococcus
kodakarensis)
PF02272
(DHHA1)
4 SER A 136
ASP A  36
SER A 138
ASN A 178
None
1.14A 2cmlA-5ghsA:
undetectable
2cmlA-5ghsA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hct ENDOTHIAPEPSIN

(Cryphonectria
parasitica)
PF00026
(Asp)
4 SER A 113
SER A  83
SER A 115
GLN A  56
None
61P  A 406 (-3.0A)
None
None
1.03A 2cmlA-5hctA:
undetectable
2cmlA-5hctA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens)
PF13855
(LRR_8)
4 SER A  71
ASP A  72
SER A  50
ASN A  93
None
1.15A 2cmlA-5hdhA:
undetectable
2cmlA-5hdhA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k04 UNCHARACTERIZED
PROTEIN


(Candida
albicans)
PF09797
(NatB_MDM20)
4 SER A  81
ASP A  78
SER A  77
SER A  89
None
0.88A 2cmlA-5k04A:
undetectable
2cmlA-5k04A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc1 ARYL-ALCOHOL OXIDASE

(Pleurotus
eryngii)
no annotation 4 SER A 210
ASP A  38
SER A 209
ASN A  15
None
1.12A 2cmlA-5oc1A:
undetectable
2cmlA-5oc1A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5p60 ENDOTHIAPEPSIN

(Cryphonectria
parasitica)
PF00026
(Asp)
4 SER A 113
SER A  83
SER A 115
GLN A  56
None
1.11A 2cmlA-5p60A:
undetectable
2cmlA-5p60A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tet ATP-CITRATE SYNTHASE

(Homo sapiens)
PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
4 SER B 574
SER B 577
GLN B 505
TRP B 502
None
1.11A 2cmlA-5tetB:
undetectable
2cmlA-5tetB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wve APOPTOTIC
PROTEASE-ACTIVATING
FACTOR 1


(Homo sapiens)
PF00400
(WD40)
PF00931
(NB-ARC)
4 SER A 891
ASP A 893
SER A 895
SER A 896
None
0.96A 2cmlA-5wveA:
7.8
2cmlA-5wveA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x4j UNCHARACTERIZED
PROTEIN


(Pyrococcus
furiosus)
no annotation 4 SER A 135
ASP A  36
SER A 137
ASN A 177
None
ZN  A 501 (-3.1A)
None
None
1.15A 2cmlA-5x4jA:
undetectable
2cmlA-5x4jA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnl OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC
OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC


(Pisum sativum)
PF01716
(MSP)
PF01789
(PsbP)
4 SER O 165
ASP P 137
SER O 155
SER O 154
None
0.93A 2cmlA-5xnlO:
undetectable
2cmlA-5xnlO:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnu PUTATIVE INTEGRAL
MEMBRANE PROTEIN


(Escherichia
coli)
no annotation 4 SER A 274
ASP A 507
SER A 506
ASN A 254
None
1.03A 2cmlA-5xnuA:
undetectable
2cmlA-5xnuA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z06 BDI_3064 PROTEIN

(Parabacteroides
distasonis)
no annotation 4 ASP A 379
ASN A 405
GLN A 469
TRP A 465
None
1.02A 2cmlA-5z06A:
undetectable
2cmlA-5z06A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus)
no annotation 4 SER A 149
SER A 151
SER A 131
ASN A 129
None
0.95A 2cmlA-5zlnA:
undetectable
2cmlA-5zlnA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus)
no annotation 5 SER A 503
ASP A 528
SER A 505
SER A 481
GLN A 399
None
1.48A 2cmlA-5zlnA:
undetectable
2cmlA-5zlnA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byw GOXA

(Pseudoalteromonas
luteoviolacea)
no annotation 4 SER B 308
SER B 310
SER B 311
ASN B 321
None
0.90A 2cmlA-6bywB:
undetectable
2cmlA-6bywB:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fi2 VEXL

(Achromobacter
denitrificans)
no annotation 4 SER A 313
SER A 259
SER A 257
GLN A 231
None
None
None
DJB  A 503 ( 3.3A)
1.05A 2cmlA-6fi2A:
undetectable
2cmlA-6fi2A:
12.24