SIMILAR PATTERNS OF AMINO ACIDS FOR 2CEO_A_T44A1395_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aei ANNEXIN XII

(Hydra vulgaris) 		PF00191
(Annexin) 		5 ALA A 197
SER A 153
LEU A 150
ASN A 146
LEU A 235
 None
 1.11A 2ceoA-1aeiA:
0.0		 2ceoA-1aeiA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1btc BETA-AMYLASE

(Glycine max) 		PF01373
(Glyco_hydro_14) 		5 LEU A  84
LEU A  39
SER A 422
LEU A 421
LEU A  42
 None
 1.00A 2ceoA-1btcA:
0.0		 2ceoA-1btcA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj2 ADENYLOSUCCINATE
SYNTHETASE

(Arabidopsis
thaliana) 		PF00709
(Adenylsucc_synt) 		5 ALA A 311
GLN A 360
LEU A 308
ASN A 300
LEU A 356
 None
 1.06A 2ceoA-1dj2A:
undetectable		 2ceoA-1dj2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1drt CLAVAMINATE SYNTHASE
1

(Streptomyces
clavuligerus) 		PF02668
(TauD) 		5 LEU A  42
LEU A  16
LEU A 100
ARG A 104
ARG A 103
 None
 1.12A 2ceoA-1drtA:
0.0		 2ceoA-1drtA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fgg GLUCURONYLTRANSFERAS
E I

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		5 LEU A 263
SER A 283
LEU A 284
LEU A 165
ARG A 161
 None
None
None
None
UDP  A 337 ( 4.5A)
 1.06A 2ceoA-1fggA:
0.0		 2ceoA-1fggA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7f HEAT SHOCK PROTEIN
33

(Escherichia
coli) 		PF01430
(HSP33) 		5 ALA A  94
LEU A  30
LEU A  47
ASN A  45
LEU A  34
 None
 1.11A 2ceoA-1i7fA:
0.0		 2ceoA-1i7fA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhg TRP OPERON REPRESSOR

(Escherichia
coli) 		PF01371
(Trp_repressor) 		5 LEU A 100
SER A  86
LEU A  89
LYS A  90
LEU A  62
 None
 1.06A 2ceoA-1jhgA:
undetectable		 2ceoA-1jhgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p88 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Escherichia
coli) 		PF00275
(EPSP_synthase) 		5 ALA A  33
LEU A 115
LEU A  90
ASN A 111
LEU A 102
 None
 1.05A 2ceoA-1p88A:
0.0		 2ceoA-1p88A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p88 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Escherichia
coli) 		PF00275
(EPSP_synthase) 		5 ALA A  33
LEU A 115
LEU A  90
LEU A  60
LEU A 102
 None
 1.11A 2ceoA-1p88A:
0.0		 2ceoA-1p88A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qq6 PROTEIN
(L-2-HALOACID
DEHALOGENASE)

(Xanthobacter
autotrophicus) 		PF00702
(Hydrolase) 		5 ALA A 197
GLN A  36
LEU A 210
SER A 194
LEU A 193
 None
 0.82A 2ceoA-1qq6A:
0.0		 2ceoA-1qq6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryl HYPOTHETICAL PROTEIN
YFBM

(Escherichia
coli) 		PF08974
(DUF1877) 		5 LEU A  34
LEU A  18
SER A  76
LEU A  77
LEU A 162
 None
 1.11A 2ceoA-1rylA:
0.0		 2ceoA-1rylA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txd RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 12

(Homo sapiens) 		PF00621
(RhoGEF) 		5 ALA A 884
GLN A 848
LEU A 845
LEU A 880
LEU A 841
 None
 1.11A 2ceoA-1txdA:
undetectable		 2ceoA-1txdA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis) 		PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C) 		5 ALA A 658
LEU A 268
LEU A 271
SER A 337
LEU A 290
 None
 1.01A 2ceoA-1ulvA:
undetectable		 2ceoA-1ulvA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w2d INOSITOL-TRISPHOSPHA
TE 3-KINASE A

(Homo sapiens) 		PF03770
(IPK) 		5 LEU A 455
LEU A 377
SER A 399
LEU A 400
LEU A 451
 None
 1.04A 2ceoA-1w2dA:
undetectable		 2ceoA-1w2dA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wl1 OCTOPRENYL-DIPHOSPHA
TE SYNTHASE

(Thermotoga
maritima) 		PF00348
(polyprenyl_synt) 		5 LEU A 189
LEU A 192
LEU A 285
LEU A 175
ARG A  55
 None
 1.00A 2ceoA-1wl1A:
undetectable		 2ceoA-1wl1A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkw FE(III)-PYOCHELIN
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		6 ALA A 102
LEU A 133
LEU A 140
LEU A  99
LEU A 178
ARG A 180
 None
 1.13A 2ceoA-1xkwA:
undetectable		 2ceoA-1xkwA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8x DIHYDROLIPOYL
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 LEU A 406
LEU A 397
SER A 447
LEU A 450
LEU A 423
 None
 0.95A 2ceoA-2a8xA:
undetectable		 2ceoA-2a8xA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmm THERMOSTABLE
HEMOGLOBIN FROM
THERMOBIFIDA FUSCA

(Thermobifida
fusca) 		PF01152
(Bac_globin) 		5 LEU A 130
LEU A 140
LEU A  83
LEU A  49
ARG A  80
 None
 1.10A 2ceoA-2bmmA:
undetectable		 2ceoA-2bmmA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bra NEDD9 INTERACTING
PROTEIN WITH
CALPONIN HOMOLOGY
AND LIM DOMAINS

(Mus musculus) 		PF01494
(FAD_binding_3) 		5 GLN A 441
LEU A 442
LEU A 469
ASN A 470
LEU A 439
 None
 1.03A 2ceoA-2braA:
undetectable		 2ceoA-2braA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cg5 L-AMINOADIPATE-SEMIA
LDEHYDE
DEHYDROGENASE-PHOSPH
OPANTETHEINYL
TRANSFERASE

(Homo sapiens) 		PF01648
(ACPS) 		5 ALA A 130
LEU A  94
LEU A 104
LYS A  84
ARG A  78
 None
MG  A1301 ( 4.9A)
None
None
MG  A1301 (-4.2A)
 1.12A 2ceoA-2cg5A:
undetectable		 2ceoA-2cg5A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmy CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR COOA-1

(Carboxydothermus
hydrogenoformans) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		5 LEU A 208
LEU A 148
SER A 186
LEU A 189
LEU A 206
 None
 1.08A 2ceoA-2fmyA:
undetectable		 2ceoA-2fmyA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ija ARYLAMINE
N-ACETYLTRANSFERASE
1

(Homo sapiens) 		PF00797
(Acetyltransf_2) 		5 LEU A 275
LEU A 279
LEU A 234
LEU A 267
ARG A  64
 None
 0.99A 2ceoA-2ijaA:
undetectable		 2ceoA-2ijaA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2is8 MOLYBDOPTERIN
BIOSYNTHESIS ENZYME,
MOAB

(Thermus
thermophilus) 		PF00994
(MoCF_biosynth) 		5 ALA A 149
LEU A 128
LEU A  67
LEU A 146
LEU A 126
 None
 1.11A 2ceoA-2is8A:
undetectable		 2ceoA-2is8A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iw1 LIPOPOLYSACCHARIDE
CORE BIOSYNTHESIS
PROTEIN RFAG

(Escherichia
coli) 		PF00534
(Glycos_transf_1)
PF13439
(Glyco_transf_4) 		5 LEU A 221
LEU A 218
ASN A 197
LEU A 331
ARG A 341
 None
 0.98A 2ceoA-2iw1A:
undetectable		 2ceoA-2iw1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4h DEOXYCYTIDINE
TRIPHOSPHATE
DEAMINASE

(Escherichia
coli) 		PF00692
(dUTPase) 		5 LEU A  99
LEU A  17
LEU A   3
LEU A 103
ARG A   2
 None
 1.02A 2ceoA-2j4hA:
undetectable		 2ceoA-2j4hA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l3g RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 7

(Homo sapiens) 		PF00307
(CH) 		6 LEU A  24
LEU A  58
SER A 113
LEU A 117
ASN A 118
LEU A  54
 None
 1.42A 2ceoA-2l3gA:
undetectable		 2ceoA-2l3gA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmp 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana) 		PF02542
(YgbB) 		5 ALA A 125
LEU A  43
ASN A 131
LEU A 119
ARG A 116
 None
 1.07A 2ceoA-2pmpA:
undetectable		 2ceoA-2pmpA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfq 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Escherichia
coli) 		PF00275
(EPSP_synthase) 		5 ALA A  84
LEU A  92
LEU A 102
LEU A  60
LEU A  90
 None
 0.98A 2ceoA-2qfqA:
undetectable		 2ceoA-2qfqA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhk NON-STRUCTURAL
PROTEIN 1

(Influenza A
virus) 		PF00600
(Flu_NS1) 		5 ALA A 155
LEU A 181
LEU A 130
LYS A 126
ASN A 190
 NO3  A   2 ( 3.7A)
None
None
NO3  A   2 (-2.7A)
None
 1.12A 2ceoA-2rhkA:
undetectable		 2ceoA-2rhkA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] LARGE CHAIN

(Azospirillum
brasilense) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		5 LEU A 606
LEU A 642
SER A 634
LEU A 631
ARG A 590
 None
 1.09A 2ceoA-2vdcA:
undetectable		 2ceoA-2vdcA:
13.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		7 ALA A  27
GLN A 238
LEU A 246
LEU A 248
LEU A 269
LYS A 270
ASN A 273
 T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 (-4.0A)
T44  A1370 (-4.8A)
T44  A1370 ( 3.3A)
 0.43A 2ceoA-2xn6A:
41.3		 2ceoA-2xn6A:
86.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		7 ALA A  27
GLN A 238
LEU A 246
LEU A 248
SER A 266
LEU A 269
ASN A 273
 T44  A1370 ( 3.9A)
T44  A1370 (-3.3A)
T44  A1370 (-4.6A)
None
T44  A1370 ( 4.1A)
T44  A1370 (-4.0A)
T44  A1370 ( 3.3A)
 0.56A 2ceoA-2xn6A:
41.3		 2ceoA-2xn6A:
86.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus) 		PF00148
(Oxidored_nitro) 		5 LEU A 108
LEU A 106
LEU A  96
LYS A  95
LEU A  44
 None
 1.10A 2ceoA-3aeuA:
undetectable		 2ceoA-3aeuA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica) 		PF14496
(NEL) 		5 LEU A 264
LEU A 267
SER A 256
LEU A 257
LEU A 260
 None
 1.07A 2ceoA-3g06A:
undetectable		 2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica) 		PF14496
(NEL) 		5 LEU A 304
LEU A 307
SER A 296
LEU A 297
LEU A 300
 None
 1.09A 2ceoA-3g06A:
undetectable		 2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica) 		PF14496
(NEL) 		5 LEU A 404
LEU A 407
SER A 396
LEU A 397
LEU A 400
 None
 1.10A 2ceoA-3g06A:
undetectable		 2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g06 SSPH2 (LEUCINE-RICH
REPEAT PROTEIN)

(Salmonella
enterica) 		PF14496
(NEL) 		5 LEU A 424
LEU A 427
SER A 416
LEU A 417
LEU A 420
 None
 1.07A 2ceoA-3g06A:
undetectable		 2ceoA-3g06A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzg PERMEASE
MOLYBDATE-BINDING
PERIPLASMIC PROTEIN

(Xanthomonas
citri) 		PF13531
(SBP_bac_11) 		5 ALA A 129
LEU A 109
LEU A 166
LEU A 115
ARG A 145
 None
 0.98A 2ceoA-3gzgA:
undetectable		 2ceoA-3gzgA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5a RESPONSE
REGULATOR/GGDEF
DOMAIN PROTEIN

(Pseudomonas
syringae group
genomosp. 3) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		5 ALA A 233
LEU A 257
LEU A 204
SER A 275
LEU A 272
 None
C2E  A 335 ( 3.6A)
None
None
None
 0.97A 2ceoA-3i5aA:
undetectable		 2ceoA-3i5aA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jc7 DNA REPLICATION
COMPLEX GINS PROTEIN
SLD5

(Saccharomyces
cerevisiae) 		PF05916
(Sld5)
PF16922
(SLD5_C) 		5 LEU D 174
SER D 155
LEU D 158
ASN D 162
LEU D 175
 None
 0.98A 2ceoA-3jc7D:
undetectable		 2ceoA-3jc7D:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lez BETA-LACTAMASE

(Oceanobacillus
iheyensis) 		PF13354
(Beta-lactamase2) 		5 ALA A 139
LEU A 104
LEU A 132
LEU A 151
ARG A 216
 None
None
None
None
CA  A   3 ( 4.8A)
 0.99A 2ceoA-3lezA:
undetectable		 2ceoA-3lezA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7m 33 KDA CHAPERONIN

(Escherichia
coli) 		PF01430
(HSP33) 		5 ALA X  94
LEU X  30
LEU X  47
ASN X  45
LEU X  34
 None
 1.06A 2ceoA-3m7mX:
undetectable		 2ceoA-3m7mX:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mt0 UNCHARACTERIZED
PROTEIN PA1789

(Pseudomonas
aeruginosa) 		PF00582
(Usp) 		5 ALA A  24
LEU A  50
LEU A  53
LEU A  21
LEU A  37
 None
 1.05A 2ceoA-3mt0A:
undetectable		 2ceoA-3mt0A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naw SECRETED EFFECTOR
PROTEIN

(Escherichia
coli) 		PF00805
(Pentapeptide)
PF13979
(SopA_C)
PF13981
(SopA) 		5 LEU A 213
LEU A 208
SER A 177
LEU A 181
LEU A 211
 None
 1.00A 2ceoA-3nawA:
undetectable		 2ceoA-3nawA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogh PROTEIN YCIE

(Escherichia
coli) 		no annotation 6 ALA B 117
LEU B  60
LEU B  56
SER B 113
LEU B 114
LEU B  11
 None
 1.46A 2ceoA-3oghB:
undetectable		 2ceoA-3oghB:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		5 LEU A  60
LEU A 124
LEU A 120
ARG A 117
ARG A 121
 FAD  A 401 (-4.6A)
None
None
FAD  A 401 (-2.8A)
FAD  A 401 (-4.6A)
 1.10A 2ceoA-3p9uA:
undetectable		 2ceoA-3p9uA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rkd CAPSID PROTEIN

(Orthohepevirus
A) 		PF03014
(SP2) 		5 LEU A 471
LEU A 539
LEU A 521
LEU A 601
ARG A 466
 None
 1.09A 2ceoA-3rkdA:
undetectable		 2ceoA-3rkdA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v65 AGRIN

(Rattus
norvegicus) 		PF00054
(Laminin_G_1) 		5 ALA A1860
LEU A1920
LEU A1800
LEU A1824
LEU A1798
 None
 0.85A 2ceoA-3v65A:
undetectable		 2ceoA-3v65A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9a ESTERASE/LIPASE

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		5 ALA A 251
LEU A 154
SER A 258
LEU A 230
LEU A 151
 None
 1.04A 2ceoA-3v9aA:
0.1		 2ceoA-3v9aA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vjj P9-1

(Rice black
streaked dwarf
virus) 		PF06043
(Reo_P9) 		5 LEU A  76
LEU A  80
SER A 189
LEU A 190
LEU A  77
 None
 1.12A 2ceoA-3vjjA:
undetectable		 2ceoA-3vjjA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbh ALKALINE PHOSPHATASE

(Halomonas sp.
#593) 		PF00245
(Alk_phosphatase) 		5 ALA A 160
LEU A 213
LEU A 215
SER A 178
LEU A 187
 None
 1.06A 2ceoA-3wbhA:
undetectable		 2ceoA-3wbhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4boc DNA-DIRECTED RNA
POLYMERASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00940
(RNA_pol)
PF14700
(RPOL_N) 		5 LEU A 408
LEU A 404
LEU A 526
LEU A 665
ARG A 518
 None
 1.09A 2ceoA-4bocA:
undetectable		 2ceoA-4bocA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ckr EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		5 ALA A 751
LEU A 837
LEU A 880
LEU A 905
LEU A 833
 None
 1.09A 2ceoA-4ckrA:
undetectable		 2ceoA-4ckrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f1p ARF-GAP WITH
COILED-COIL, ANK
REPEAT AND PH
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF01412
(ArfGap)
PF12796
(Ank_2) 		5 ALA A 614
LEU A 476
LEU A 472
ASN A 629
LEU A 585
 None
 0.97A 2ceoA-4f1pA:
undetectable		 2ceoA-4f1pA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4flc ADENYLOSUCCINATE
LYASE

(Homo sapiens) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		5 LEU A 128
LEU A 131
SER A 261
LEU A 258
LEU A 186
 None
 0.96A 2ceoA-4flcA:
undetectable		 2ceoA-4flcA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsf PENICILLIN-BINDING
PROTEIN 3

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		5 LEU A 391
LEU A 375
SER A 294
LYS A 297
LEU A 411
 None
None
0W0  A 601 (-1.4A)
0W0  A 601 ( 4.2A)
None
 1.00A 2ceoA-4fsfA:
undetectable		 2ceoA-4fsfA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fww MACROPHAGE-STIMULATI
NG PROTEIN RECEPTOR

(Homo sapiens) 		PF01403
(Sema) 		5 LEU A 296
LEU A 298
SER A 326
LEU A 346
LEU A 280
 None
 1.03A 2ceoA-4fwwA:
undetectable		 2ceoA-4fwwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grv NEUROTENSIN RECEPTOR
TYPE 1, LYSOZYME
CHIMERA

(Escherichia
virus T4;
Rattus
norvegicus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 LEU A 118
SER A 108
LEU A 111
ASN A  82
LEU A 115
 None
 1.11A 2ceoA-4grvA:
undetectable		 2ceoA-4grvA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h32 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		5 LEU A  61
LEU A  65
SER A 233
LEU A 174
LEU A 105
 None
 1.10A 2ceoA-4h32A:
undetectable		 2ceoA-4h32A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4izd ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Ruegeria
pomeroyi) 		PF00378
(ECH_1) 		5 ALA A 126
LEU A  35
LEU A  43
LEU A  60
LEU A 122
 None
 1.11A 2ceoA-4izdA:
undetectable		 2ceoA-4izdA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ln1 L-LACTATE
DEHYDROGENASE 1

(Bacillus cereus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 ALA A 172
LEU A 200
LEU A 211
LEU A 159
LEU A 196
 None
 1.09A 2ceoA-4ln1A:
undetectable		 2ceoA-4ln1A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nkh E3 UBIQUITIN-PROTEIN
LIGASE SSPH1

(Salmonella
enterica) 		no annotation 5 LEU A 279
LEU A 282
SER A 271
LEU A 272
LEU A 275
 None
 1.12A 2ceoA-4nkhA:
undetectable		 2ceoA-4nkhA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oj5 TAILSPIKE PROTEIN

(Escherichia
virus CBA120) 		no annotation 5 LEU A 329
LEU A 238
LEU A 205
LYS A 206
LEU A 272
 None
 1.03A 2ceoA-4oj5A:
undetectable		 2ceoA-4oj5A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		5 LEU A 295
LEU A 298
SER A 287
LEU A 288
LEU A 291
 None
 1.10A 2ceoA-4ow2A:
undetectable		 2ceoA-4ow2A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		5 LEU A 355
LEU A 358
SER A 347
LEU A 348
LEU A 351
 None
 1.07A 2ceoA-4ow2A:
undetectable		 2ceoA-4ow2A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow2 YOP EFFECTOR YOPM

(Yersinia
enterocolitica) 		PF12468
(TTSSLRR) 		5 LEU A 415
LEU A 418
SER A 407
LEU A 408
LEU A 411
 None
 1.10A 2ceoA-4ow2A:
undetectable		 2ceoA-4ow2A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4plj CAPSID PROTEIN

(Orthohepevirus
A) 		PF03014
(SP2) 		5 LEU A 471
LEU A 539
LEU A 521
LEU A 601
ARG A 466
 None
 0.93A 2ceoA-4pljA:
undetectable		 2ceoA-4pljA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmk TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN EXOU

(Pseudomonas
fluorescens) 		PF01734
(Patatin) 		5 LEU A 441
LEU A 448
ASN A 430
LEU A 458
ARG A 461
 None
 1.09A 2ceoA-4qmkA:
undetectable		 2ceoA-4qmkA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rly NAV1.2 - ANKB
CHIMERA

(Homo sapiens;
Mus musculus) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4) 		5 ALA A2240
LEU A2212
LEU A2252
LEU A2196
ARG A2228
 None
 0.99A 2ceoA-4rlyA:
undetectable		 2ceoA-4rlyA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ruw ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE

(Beutenbergia
cavernae) 		PF03372
(Exo_endo_phos) 		5 LEU A 435
LEU A 380
SER A 361
LEU A 360
LEU A 416
 None
 1.11A 2ceoA-4ruwA:
undetectable		 2ceoA-4ruwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxl MOLYBDENUM ABC
TRANSPORTER,
PERIPLASMIC
MOLYBDENUM-BINDING
PROTEIN

(Vibrio cholerae) 		PF13531
(SBP_bac_11) 		5 ALA A 150
LEU A 131
LEU A 187
LEU A 136
ARG A 166
 None
 1.04A 2ceoA-4rxlA:
undetectable		 2ceoA-4rxlA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tlv ADP-RIBOSYLATING
TOXIN CARDS

(Mycoplasma
pneumoniae) 		PF02917
(Pertussis_S1) 		5 LEU A 277
LEU A 403
SER A 336
LEU A 337
LEU A 288
 None
 0.93A 2ceoA-4tlvA:
undetectable		 2ceoA-4tlvA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1

(Mus musculus) 		PF00307
(CH)
PF01494
(FAD_binding_3) 		5 GLN A 441
LEU A 442
LEU A 469
ASN A 470
LEU A 439
 None
 1.01A 2ceoA-4txkA:
undetectable		 2ceoA-4txkA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN

(Salmonella
enterica) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1) 		5 LEU A1414
LEU A1377
LEU A1404
LEU A1422
ARG A1167
 None
 1.02A 2ceoA-4u48A:
undetectable		 2ceoA-4u48A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uad IMPORTIN SUBUNIT
ALPHA-7

(Homo sapiens) 		PF00514
(Arm)
PF16186
(Arm_3) 		5 LEU A 299
LEU A 261
SER A 266
LEU A 269
LEU A 302
 None
 1.04A 2ceoA-4uadA:
undetectable		 2ceoA-4uadA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzv HEMOGLOBIN

(Thermobifida
fusca) 		PF01152
(Bac_globin) 		6 LEU A 130
LEU A 140
LEU A  83
LEU A  49
ARG A  48
ARG A  80
 None
None
HEM  A1157 (-4.9A)
None
None
None
 1.27A 2ceoA-4uzvA:
undetectable		 2ceoA-4uzvA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v3q YIII_M4_AII

(synthetic
construct) 		PF00514
(Arm)
PF16186
(Arm_3) 		5 LEU A  61
LEU A  58
LEU A  35
LYS A  34
LEU A  20
 None
 1.09A 2ceoA-4v3qA:
undetectable		 2ceoA-4v3qA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Drosophila
melanogaster) 		PF07034
(ORC3_N) 		5 ALA C 143
LEU C 240
LEU C 238
LEU C 223
LEU C 209
 None
 0.67A 2ceoA-4xgcC:
undetectable		 2ceoA-4xgcC:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yxc FLAGELLAR MOTOR
SWITCH PROTEIN
FLIM,FLAGELLAR MOTOR
SWITCH PROTEIN FLIN

(Salmonella
enterica) 		PF01052
(FliMN_C)
PF16973
(FliN_N) 		5 ALA B  23
LEU B  80
LEU B 171
LEU B  21
LEU B  62
 None
 1.12A 2ceoA-4yxcB:
undetectable		 2ceoA-4yxcB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF07678
(A2M_comp) 		5 LEU A1423
LEU A1386
LEU A1413
LEU A1431
ARG A1175
 None
 0.94A 2ceoA-4ziuA:
undetectable		 2ceoA-4ziuA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zn2 PSLG

(Pseudomonas
aeruginosa) 		PF00150
(Cellulase) 		5 LEU A 115
LEU A 150
SER A  96
LEU A  97
LEU A  80
 None
 1.04A 2ceoA-4zn2A:
undetectable		 2ceoA-4zn2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF11974
(MG1) 		5 LEU A1423
LEU A1386
LEU A1413
LEU A1431
ARG A1175
 None
 1.06A 2ceoA-5a42A:
undetectable		 2ceoA-5a42A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1i TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI

(Thermus
thermophilus) 		PF08704
(GCD14) 		5 ALA A 208
LEU A 169
LEU A 178
LEU A 191
ARG A 251
 None
 1.04A 2ceoA-5c1iA:
undetectable		 2ceoA-5c1iA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cio PYRROLOQUINOLINE
QUINONE BIOSYNTHESIS
PROTEIN PQQF

(Serratia sp.
FS14) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		5 ALA A 477
LEU A 505
LEU A 503
LEU A 523
ASN A 520
 None
 1.06A 2ceoA-5cioA:
undetectable		 2ceoA-5cioA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fg0 E3 UBIQUITIN-PROTEIN
LIGASE LISTERIN

(Saccharomyces
cerevisiae) 		no annotation 5 LEU A 361
LEU A 314
LEU A 295
LYS A 338
LEU A 317
 None
 1.12A 2ceoA-5fg0A:
undetectable		 2ceoA-5fg0A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl3 PILI RETRACTION
PROTEIN PILT

(Thermus
thermophilus) 		PF00437
(T2SSE) 		5 ALA A 316
LEU A 266
LEU A 270
LEU A 294
LEU A 304
 None
 0.98A 2ceoA-5fl3A:
undetectable		 2ceoA-5fl3A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmg PROTEASOME SUBUNIT
ALPHA TYPE

(Plasmodium
falciparum) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		5 ALA C 163
LEU C 191
SER C 172
LEU C 175
LEU C  37
 None
 1.00A 2ceoA-5fmgC:
undetectable		 2ceoA-5fmgC:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5glg FUMARATE REDUCTASE 2

(Saccharomyces
cerevisiae) 		PF00890
(FAD_binding_2) 		5 LEU A 140
LEU A 132
SER A 172
LEU A 171
LEU A 138
 None
 1.10A 2ceoA-5glgA:
undetectable		 2ceoA-5glgA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr8 LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE PEPR1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		5 LEU A 272
LEU A 248
SER A 234
LEU A 235
LEU A 274
 None
 1.11A 2ceoA-5gr8A:
undetectable		 2ceoA-5gr8A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30

(Danio rerio) 		PF00443
(UCH) 		5 LEU A 247
SER A 346
LEU A 347
LEU A 317
ARG A 491
 None
 1.00A 2ceoA-5gviA:
undetectable		 2ceoA-5gviA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hso UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887

(Mycobacterium
tuberculosis) 		PF01047
(MarR) 		5 ALA A  78
LEU A  28
LEU A  31
LEU A 102
LEU A  33
 None
 1.04A 2ceoA-5hsoA:
undetectable		 2ceoA-5hsoA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5icg (S)-NORCOCLAURINE
6-O-METHYLTRANSFERAS
E

(Thalictrum
flavum) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		5 LEU A  70
LEU A  52
SER A  58
LEU A  56
LEU A  66
 None
 1.11A 2ceoA-5icgA:
undetectable		 2ceoA-5icgA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5it5 ATP BINDING
MOTIF-CONTAINING
PROTEIN PILF

(Thermus
thermophilus) 		no annotation 5 ALA F 726
LEU F 769
LEU F 755
LEU F 646
ARG F 754
 None
 1.07A 2ceoA-5it5F:
undetectable		 2ceoA-5it5F:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjo UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08238
(Sel1) 		5 ALA A 213
LEU A 246
LEU A 249
SER A 214
LEU A 268
 None
 0.96A 2ceoA-5jjoA:
undetectable		 2ceoA-5jjoA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ktk POLYKETIDE SYNTHASE
PKSJ

(Bacillus
subtilis) 		PF08659
(KR) 		5 ALA A  40
LEU A 147
LEU A 154
LEU A 107
LEU A 118
 None
 1.12A 2ceoA-5ktkA:
undetectable		 2ceoA-5ktkA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n2i REDUCED COENZYME
F420:NADP
OXIDOREDUCTASE

(Thermobifida
fusca) 		PF03807
(F420_oxidored) 		5 ALA A  77
LEU A 141
LEU A  97
LEU A  25
LEU A 104
 None
 1.10A 2ceoA-5n2iA:
undetectable		 2ceoA-5n2iA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6v AMYLOSUCRASE

(Neisseria
polysaccharea) 		no annotation 5 LEU A   7
LEU A  61
LEU A  43
LYS A  42
LEU A  65
 None
 1.12A 2ceoA-5n6vA:
undetectable		 2ceoA-5n6vA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv6 TRANSFORMING GROWTH
FACTOR-BETA-INDUCED
PROTEIN IG-H3

(Homo sapiens) 		PF02469
(Fasciclin) 		5 ALA A 525
LEU A 509
LEU A 518
LEU A 569
LYS A 570
 None
 0.93A 2ceoA-5nv6A:
undetectable		 2ceoA-5nv6A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xs2 CYCLIN-C

(Homo sapiens) 		PF00134
(Cyclin_N)
PF16899
(Cyclin_C_2) 		5 LEU B  40
SER B  77
LEU B  78
LYS B  79
LEU B  32
 None
 1.06A 2ceoA-5xs2B:
undetectable		 2ceoA-5xs2B:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 5 LEU A 211
LEU A 206
SER A 162
LEU A 158
LEU A 188
 None
 0.90A 2ceoA-5y3jA:
undetectable		 2ceoA-5y3jA:
12.19