SIMILAR PATTERNS OF AMINO ACIDS FOR 2CDQ_B_SAMB1500_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
16vp PROTEIN (VP16,
VMW65, ATIF)

(Human
alphaherpesvirus
1) 		PF02232
(Alpha_TIF) 		4 SER A 177
SER A 186
ARG A 214
GLU A 218
 None
 1.01A 2cdqB-16vpA:
undetectable		 2cdqB-16vpA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1coo RNA POLYMERASE ALPHA
SUBUNIT

(Escherichia
coli) 		PF03118
(RNA_pol_A_CTD) 		4 SER A 266
ARG A 284
LEU A 289
GLU A 273
 None
 1.05A 2cdqB-1cooA:
undetectable		 2cdqB-1cooA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cwp COAT PROTEIN

(Cowpea
chlorotic
mottle virus) 		PF01318
(Bromo_coat) 		4 SER A 130
ASP A 128
SER A 160
LEU A  97
 None
 1.11A 2cdqB-1cwpA:
undetectable		 2cdqB-1cwpA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dwa MYROSINASE MA1

(Sinapis alba) 		PF00232
(Glyco_hydro_1) 		4 ASP M 162
SER M 110
ARG M 111
GLU M 151
 None
SO4  M 925 ( 4.3A)
SO4  M 925 (-3.8A)
None
 0.77A 2cdqB-1dwaM:
0.0		 2cdqB-1dwaM:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0i PHOSPHOLIPASE D

(Streptomyces
sp. PMF) 		PF13091
(PLDc_2) 		4 SER A 480
SER A  34
ARG A  32
LEU A  11
 None
 1.03A 2cdqB-1f0iA:
0.0		 2cdqB-1f0iA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fc4 2-AMINO-3-KETOBUTYRA
TE CONENZYME A
LIGASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 SER A 109
ASP A 113
ARG A 265
GLU A  93
 None
 1.09A 2cdqB-1fc4A:
1.3		 2cdqB-1fc4A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		4 SER A 394
SER A 450
ARG A 451
GLU A 274
 None
 1.07A 2cdqB-1hn0A:
undetectable		 2cdqB-1hn0A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nr4 THYMUS AND
ACTIVATION-REGULATED
CHEMOKINE

(Homo sapiens) 		PF00048
(IL8) 		4 SER A  35
ARG A  36
LEU A  12
GLU A  13
 SO4  A9199 (-4.6A)
None
SO4  A9199 (-4.1A)
None
 1.01A 2cdqB-1nr4A:
undetectable		 2cdqB-1nr4A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oyz HYPOTHETICAL PROTEIN
YIBA

(Escherichia
coli) 		PF13646
(HEAT_2) 		4 ASP A  26
ARG A  57
LEU A  58
GLU A  61
 None
 1.02A 2cdqB-1oyzA:
0.0		 2cdqB-1oyzA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1u CHOLINE
O-ACETYLTRANSFERASE

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 SER A 264
ASP A 263
ARG A 257
GLU A 274
 None
 1.10A 2cdqB-1t1uA:
0.0		 2cdqB-1t1uA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1twy ABC TRANSPORTER,
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN

(Vibrio cholerae) 		PF12727
(PBP_like) 		4 SER A  83
ARG A  84
LEU A  86
GLU A  90
 PO4  A1500 (-2.7A)
None
None
None
 0.82A 2cdqB-1twyA:
undetectable		 2cdqB-1twyA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcj NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 ASP A 194
TRP A 177
LEU A 132
GLU A 117
 None
None
None
IBA  A   1 (-3.9A)
 0.99A 2cdqB-1vcjA:
undetectable		 2cdqB-1vcjA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xv5 DNA
ALPHA-GLUCOSYLTRANSF
ERASE

(Escherichia
virus T4) 		PF11440
(AGT) 		4 SER A1387
SER A1304
ARG A1303
GLU A1393
 None
None
EDO  A1404 ( 4.6A)
EDO  A1404 (-4.1A)
 0.95A 2cdqB-1xv5A:
undetectable		 2cdqB-1xv5A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ys7 TRANSCRIPTIONAL
REGULATORY PROTEIN
PRRA

(Mycobacterium
tuberculosis) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 SER A  68
ASP A  65
SER A  86
LEU A  57
 None
 0.91A 2cdqB-1ys7A:
1.9		 2cdqB-1ys7A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN

(Homo sapiens;
Homo sapiens) 		PF07686
(V-set)
PF07686
(V-set) 		4 SER L 135
TRP L 109
SER H 134
LEU L 138
 None
 0.98A 2cdqB-2a9mL:
undetectable		 2cdqB-2a9mL:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ab4 TRNA PSEUDOURIDINE
SYNTHASE B

(Thermotoga
maritima) 		PF01472
(PUA)
PF01509
(TruB_N)
PF16198
(TruB_C_2) 		4 ASP A  81
ARG A 157
LEU A  75
GLU A  89
 C  B  11 ( 2.8A)
None
None
None
 0.86A 2cdqB-2ab4A:
undetectable		 2cdqB-2ab4A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4m GLYCOGEN
PHOSPHORYLASE

(Corynebacterium
callunae) 		PF00343
(Phosphorylase) 		4 SER A 268
ARG A 308
LEU A 309
GLU A 313
 None
FMT  A1797 ( 4.4A)
None
None
 1.03A 2cdqB-2c4mA:
3.4		 2cdqB-2c4mA:
22.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2cdq ASPARTOKINASE

(Arabidopsis
thaliana) 		PF00696
(AA_kinase) 		7 SER A 371
ASP A 387
TRP A 392
SER A 393
ARG A 394
LEU A 396
GLU A 400
 LYS  A 600 ( 3.3A)
SAM  A1500 (-4.7A)
SAM  A1500 (-3.7A)
SAM  A1500 (-2.6A)
SAM  A1500 (-3.7A)
SAM  A1500 (-4.1A)
SAM  A1500 (-3.8A)
 0.25A 2cdqB-2cdqA:
59.7		 2cdqB-2cdqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpw HYPOTHETICAL PROTEIN
TTHA0179

(Thermus
thermophilus) 		PF12804
(NTP_transf_3) 		4 SER A 154
ASP A 152
SER A   4
LEU A  80
 None
 1.01A 2cdqB-2dpwA:
undetectable		 2cdqB-2dpwA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g28 PYRUVATE
DEHYDROGENASE E1
COMPONENT

(Escherichia
coli) 		PF00456
(Transketolase_N) 		4 SER A 753
ARG A 859
LEU A 856
GLU A 861
 None
 0.94A 2cdqB-2g28A:
undetectable		 2cdqB-2g28A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g39 ACETYL-COA HYDROLASE

(Pseudomonas
aeruginosa) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 ASP A 107
SER A  67
LEU A 110
GLU A 288
 None
None
ACY  A 901 (-4.9A)
ACY  A 901 (-2.6A)
 1.07A 2cdqB-2g39A:
undetectable		 2cdqB-2g39A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h21 RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E

(Pisum sativum) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		4 SER A 428
ASP A 155
SER A 161
GLU A 167
 None
 1.04A 2cdqB-2h21A:
undetectable		 2cdqB-2h21A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjv ATP-DEPENDENT RNA
HELICASE DBPA

(Bacillus
subtilis) 		PF00271
(Helicase_C) 		4 ASP A 354
SER A 323
ARG A 327
LEU A 317
 None
 1.08A 2cdqB-2hjvA:
undetectable		 2cdqB-2hjvA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ich PUTATIVE ATTH

(Nitrosomonas
europaea) 		PF07143
(CrtC)
PF17186
(Lipocalin_9) 		4 SER A 187
ASP A 213
TRP A 211
LEU A 191
 None
 1.07A 2cdqB-2ichA:
undetectable		 2cdqB-2ichA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lev LER

(Escherichia
coli) 		PF00816
(Histone_HNS) 		4 SER A  17
SER A   2
LEU A  40
GLU A  37
 None
 0.94A 2cdqB-2levA:
undetectable		 2cdqB-2levA:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n6j ZINC METALLOPROTEASE
ZMP1

(Clostridioides
difficile) 		PF07737
(ATLF) 		4 SER A 157
ASP A 149
SER A 190
LEU A 218
 None
 0.95A 2cdqB-2n6jA:
undetectable		 2cdqB-2n6jA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq5 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Streptococcus
mutans) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 SER A  64
ASP A  71
LEU A 138
GLU A 141
 None
 0.94A 2cdqB-2nq5A:
undetectable		 2cdqB-2nq5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvv ACETYL-COA
HYDROLASE/TRANSFERAS
E FAMILY PROTEIN

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 ASP A 102
SER A  62
LEU A 105
GLU A 284
 ASP  A 102 ( 0.6A)
SER  A  62 ( 0.0A)
LEU  A 105 ( 0.6A)
GLU  A 284 ( 0.5A)
 1.10A 2cdqB-2nvvA:
undetectable		 2cdqB-2nvvA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2g DIENELACTONE
HYDROLASE

(Trichormus
variabilis) 		PF01738
(DLH) 		4 SER A  95
ARG A  96
LEU A  72
GLU A  76
 None
 0.80A 2cdqB-2o2gA:
undetectable		 2cdqB-2o2gA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ouw ALKYLHYDROPEROXIDASE
AHPD CORE

(Rhodospirillum
rubrum) 		PF02627
(CMD) 		4 ASP A  44
ARG A   5
LEU A   7
GLU A  11
 None
 1.01A 2cdqB-2ouwA:
undetectable		 2cdqB-2ouwA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p58 PUTATIVE TYPE III
SECRETION PROTEIN
YSCG

(Yersinia pestis) 		PF09477
(Type_III_YscG) 		4 SER C  89
ARG C  93
LEU C  94
GLU C  71
 None
 0.96A 2cdqB-2p58C:
undetectable		 2cdqB-2p58C:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5i BH3822 PROTEIN

(Bacillus
halodurans) 		PF03099
(BPL_LplA_LipB) 		4 SER A  32
ARG A  16
LEU A 255
GLU A 259
 None
 0.98A 2cdqB-2p5iA:
0.5		 2cdqB-2p5iA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qup BH1478 PROTEIN

(Bacillus
halodurans) 		PF03885
(DUF327) 		4 SER A  48
ASP A  52
LEU A  72
GLU A  75
 None
 1.10A 2cdqB-2qupA:
undetectable		 2cdqB-2qupA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyv XAA-HIS DIPEPTIDASE

(Histophilus
somni) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 SER A  26
ASP A  78
ARG A  49
GLU A  30
 None
 0.96A 2cdqB-2qyvA:
undetectable		 2cdqB-2qyvA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5s PROCESSED GLYCEROL
PHOSPHATE
LIPOTEICHOIC ACID
SYNTHASE

(Staphylococcus
aureus) 		PF00884
(Sulfatase) 		4 SER A 408
ASP A 344
ARG A 356
GLU A 304
 None
None
GP9  A1644 (-3.0A)
None
 0.96A 2cdqB-2w5sA:
undetectable		 2cdqB-2w5sA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzs PUTATIVE
UNCHARACTERIZED
PROTEIN

(Aquifex
aeolicus) 		PF01867
(Cas_Cas1) 		4 SER A 203
ASP A 218
SER A 106
LEU A 297
 None
 0.86A 2cdqB-2yzsA:
undetectable		 2cdqB-2yzsA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc2 DNAD-LIKE
REPLICATION PROTEIN

(Streptococcus
mutans) 		PF07261
(DnaB_2) 		4 ASP A 130
ARG A 137
LEU A 139
GLU A 143
 ZN  A 507 (-1.9A)
None
None
None
 0.90A 2cdqB-2zc2A:
undetectable		 2cdqB-2zc2A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 SER B  58
ASP B  37
SER B  34
LEU B  50
 None
 1.09A 2cdqB-3a79B:
undetectable		 2cdqB-3a79B:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		4 ASP A  87
ARG A 164
LEU A 169
GLU A 171
 None
 0.82A 2cdqB-3aqiA:
1.5		 2cdqB-3aqiA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1

(Homo sapiens) 		PF12796
(Ank_2)
PF13637
(Ank_4) 		4 ASP A 839
TRP A 848
LEU A 814
GLU A 784
 None
 1.11A 2cdqB-3b95A:
undetectable		 2cdqB-3b95A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 SER A  54
ASP A  52
LEU A 348
GLU A 337
 None
 0.94A 2cdqB-3bgaA:
undetectable		 2cdqB-3bgaA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN

(Chromobacterium
violaceum) 		PF03536
(VRP3) 		5 SER A  50
SER A 185
ARG A 186
LEU A 124
GLU A  54
 None
 1.33A 2cdqB-3bo6A:
1.7		 2cdqB-3bo6A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ch4 PHOSPHOMEVALONATE
KINASE

(Homo sapiens) 		PF04275
(P-mevalo_kinase) 		4 SER B  31
ARG B  32
LEU B 181
GLU B 178
 None
 0.92A 2cdqB-3ch4B:
undetectable		 2cdqB-3ch4B:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3co8 ALANINE RACEMASE

(Oenococcus oeni) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 SER A 159
ASP A 161
LEU A 127
GLU A 147
 None
 0.93A 2cdqB-3co8A:
undetectable		 2cdqB-3co8A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gu0 TRIGGER FACTOR

(Thermotoga
maritima) 		PF05697
(Trigger_N)
PF05698
(Trigger_C) 		4 ASP A 140
SER A 240
LEU A 255
GLU A 258
 None
 1.07A 2cdqB-3gu0A:
undetectable		 2cdqB-3gu0A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7f SERINE
HYDROXYMETHYLTRANSFE
RASE 1

(Mycobacterium
tuberculosis) 		PF00464
(SHMT) 		4 SER A 249
ARG A  60
LEU A  56
GLU A  72
 None
 1.09A 2cdqB-3h7fA:
undetectable		 2cdqB-3h7fA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7t 6-HYDROXY-L-NICOTINE
OXIDASE

(Paenarthrobacter
nicotinovorans) 		PF01593
(Amino_oxidase) 		4 ASP A 312
ARG A  89
LEU A 348
GLU A 350
 None
 1.11A 2cdqB-3k7tA:
undetectable		 2cdqB-3k7tA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5f N-CARBAMOYL-L-AMINO
ACID HYDROLASE

(Geobacillus
stearothermophilus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ASP A 357
ARG A 177
LEU A  75
GLU A 117
 None
 0.98A 2cdqB-3n5fA:
undetectable		 2cdqB-3n5fA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ovg AMIDOHYDROLASE

(Mycoplasma
synoviae) 		PF02126
(PTE) 		4 SER A 109
ASP A 106
ARG A 163
LEU A 164
 None
 1.11A 2cdqB-3ovgA:
undetectable		 2cdqB-3ovgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3owa ACYL-COA
DEHYDROGENASE

(Bacillus
anthracis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 ASP A  22
ARG A 324
LEU A 508
GLU A 504
 None
 1.09A 2cdqB-3owaA:
undetectable		 2cdqB-3owaA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q58 N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE

(Salmonella
enterica) 		PF04131
(NanE) 		4 SER A   2
ARG A 123
LEU A 128
GLU A 148
 PEG  A 241 ( 3.8A)
PEG  A 234 (-3.9A)
None
PEG  A 234 ( 4.4A)
 1.07A 2cdqB-3q58A:
undetectable		 2cdqB-3q58A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9p ACKA

(Mycobacterium
avium) 		PF00871
(Acetate_kinase) 		4 SER A 237
ASP A 235
LEU A 257
GLU A 254
 None
 0.97A 2cdqB-3r9pA:
undetectable		 2cdqB-3r9pA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t79 KLLA0E03807P

(Kluyveromyces
lactis) 		PF16787
(NDC10_II) 		4 SER A 294
ASP A 169
LEU A 315
GLU A 308
 None
 1.09A 2cdqB-3t79A:
undetectable		 2cdqB-3t79A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxs CRYPTOCHROME B

(Rhodobacter
sphaeroides) 		PF04244
(DPRP) 		4 SER A 431
ARG A 188
LEU A 259
GLU A 248
 None
 1.05A 2cdqB-3zxsA:
3.8		 2cdqB-3zxsA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgu MALATE DEHYDROGENASE

(Haloferax
volcanii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ASP A 124
ARG A 138
LEU A 251
GLU A 254
 None
 0.91A 2cdqB-4bguA:
2.0		 2cdqB-4bguA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cpn NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 ASP A 193
TRP A 176
LEU A 131
GLU A 116
 None
None
None
ZMR  A 700 (-3.5A)
 1.05A 2cdqB-4cpnA:
undetectable		 2cdqB-4cpnA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0q RESTRICTION
ENDONUCLEASE

(Mycobacterium
sp. JLS) 		PF04471
(Mrr_cat) 		4 SER A  80
ARG A 140
LEU A 141
GLU A 149
 None
 1.11A 2cdqB-4f0qA:
undetectable		 2cdqB-4f0qA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gd5 PHOSPHATE ABC
TRANSPORTER,
PHOSPHATE-BINDING
PROTEIN

(Clostridium
perfringens) 		PF12849
(PBP_like_2) 		4 SER A  89
ARG A  90
LEU A  92
GLU A  96
 PO4  A 301 (-2.7A)
None
None
None
 0.73A 2cdqB-4gd5A:
undetectable		 2cdqB-4gd5A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq2 NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 SER M 253
ASP M 255
SER M 275
LEU M 279
 None
 0.81A 2cdqB-4gq2M:
undetectable		 2cdqB-4gq2M:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gri GLUTAMATE--TRNA
LIGASE

(Borreliella
burgdorferi) 		PF00749
(tRNA-synt_1c) 		4 ASP A 203
ARG A   5
LEU A  39
GLU A  71
 None
 0.97A 2cdqB-4griA:
undetectable		 2cdqB-4griA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1x PHOSPHATE-BINDING
PROTEIN PSTS 2

(Streptococcus
pneumoniae) 		PF12849
(PBP_like_2) 		4 SER A 237
ARG A 238
LEU A 240
GLU A 244
 None
 0.79A 2cdqB-4h1xA:
undetectable		 2cdqB-4h1xA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hu0 CELLULASE

(uncultured
bacterium) 		PF00150
(Cellulase) 		4 SER A  79
ASP A 331
TRP A 334
GLU A 289
 None
None
CTT  A 401 ( 3.8A)
CTT  A 401 (-2.9A)
 1.05A 2cdqB-4hu0A:
undetectable		 2cdqB-4hu0A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4itu SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Xanthobacter
autotrophicus) 		PF13561
(adh_short_C2) 		4 SER A 123
ARG A 133
LEU A  85
GLU A  79
 None
 1.10A 2cdqB-4ituA:
undetectable		 2cdqB-4ituA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 SER A 756
TRP A 963
LEU A 683
GLU A 685
 None
 1.00A 2cdqB-4iugA:
undetectable		 2cdqB-4iugA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv5 ASPARTATE
CARBAMOYLTRANSFERASE
, PUTATIVE

(Trypanosoma
cruzi) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 SER A  22
ASP A  25
SER A  17
LEU A 182
 None
 1.11A 2cdqB-4iv5A:
undetectable		 2cdqB-4iv5A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhr G-PROTEIN-SIGNALING
MODULATOR 2

(Mus musculus) 		PF02188
(GoLoco)
PF13176
(TPR_7)
PF13424
(TPR_12) 		4 ASP A 176
SER A 183
LEU A 138
GLU A 134
 None
 1.05A 2cdqB-4jhrA:
undetectable		 2cdqB-4jhrA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf7 NUP188

(Thermothelomyces
thermophila) 		PF10487
(Nup188) 		4 SER A 624
ASP A 621
ARG A 767
GLU A 756
 None
 0.96A 2cdqB-4kf7A:
undetectable		 2cdqB-4kf7A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kyi VIPD

(Legionella
pneumophila) 		PF01734
(Patatin) 		4 SER A  80
ARG A 222
LEU A 218
GLU A 253
 None
 1.01A 2cdqB-4kyiA:
undetectable		 2cdqB-4kyiA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mym GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Nocardioides
sp. JS614) 		PF00903
(Glyoxalase) 		4 SER A  36
ASP A  43
LEU A  19
GLU A  20
 None
 1.12A 2cdqB-4mymA:
undetectable		 2cdqB-4mymA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n3w CREB-BINDING PROTEIN

(Homo sapiens) 		PF00439
(Bromodomain)
PF06001
(DUF902) 		4 SER A1136
ASP A1134
SER A1108
LEU A1098
 None
 1.01A 2cdqB-4n3wA:
undetectable		 2cdqB-4n3wA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3z COPN

(Chlamydia
pneumoniae) 		PF07201
(HrpJ) 		4 SER A 143
ASP A 147
LEU A 112
GLU A 111
 None
 1.10A 2cdqB-4p3zA:
undetectable		 2cdqB-4p3zA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxd ALLANTOATE
AMIDOHYDROLASE

(Escherichia
coli) 		PF01546
(Peptidase_M20) 		4 ASP A 359
ARG A 180
LEU A  77
GLU A 119
 None
 1.09A 2cdqB-4pxdA:
2.3		 2cdqB-4pxdA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8u DNA POLYMERASE IV

(Escherichia
coli) 		PF00817
(IMS)
PF11798
(IMS_HHH)
PF11799
(IMS_C) 		4 SER B  84
SER B  92
ARG B  93
GLU B 134
 None
 0.80A 2cdqB-4r8uB:
3.1		 2cdqB-4r8uB:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s1t URIDYLATE-SPECIFIC
ENDORIBONUCLEASE

(Human
coronavirus
229E) 		PF06471
(NSP11) 		4 SER A 242
ASP A 240
ARG A 257
LEU A 258
 None
 0.98A 2cdqB-4s1tA:
undetectable		 2cdqB-4s1tA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8d SULFOXIDE SYNTHASE
EGTB

(Mycolicibacterium
thermoresistibile) 		PF03781
(FGE-sulfatase)
PF12867
(DinB_2) 		4 SER A 110
ASP A 114
LEU A  61
GLU A  57
 None
 1.03A 2cdqB-4x8dA:
undetectable		 2cdqB-4x8dA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkb YCF53-LIKE PROTEIN

(Synechocystis
sp. PCC 6803) 		PF05419
(GUN4)
PF16416
(GUN4_N) 		4 ASP A 114
ARG A 127
LEU A 130
GLU A 134
 None
 1.03A 2cdqB-4xkbA:
undetectable		 2cdqB-4xkbA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xly UNCHARACTERIZED
PROTEIN BLR2150

(Bradyrhizobium
diazoefficiens) 		no annotation 4 SER A 176
ASP A 125
ARG A 113
LEU A 116
 None
 0.98A 2cdqB-4xlyA:
undetectable		 2cdqB-4xlyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b01 MOEN5

(Streptomyces
viridosporus) 		no annotation 4 SER A 143
ARG A 139
LEU A 221
GLU A 220
 None
 1.09A 2cdqB-5b01A:
undetectable		 2cdqB-5b01A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eil TRI-05

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 101
SER A 131
LEU A 141
GLU A 144
 None
 1.10A 2cdqB-5eilA:
undetectable		 2cdqB-5eilA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esr HALOALKANE
DEHALOGENASE

(Caulobacter
vibrioides) 		PF00561
(Abhydrolase_1) 		4 SER A  57
ARG A 185
LEU A 187
GLU A 191
 None
 1.07A 2cdqB-5esrA:
undetectable		 2cdqB-5esrA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hqn SPHINGOMYELIN
PHOSPHODIESTERASE

(Mus musculus) 		PF00149
(Metallophos) 		4 SER A 471
ARG A 472
LEU A 474
GLU A 445
 None
 1.01A 2cdqB-5hqnA:
undetectable		 2cdqB-5hqnA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8g CREB-BINDING PROTEIN

(Homo sapiens) 		PF00439
(Bromodomain)
PF06001
(DUF902) 		4 SER A1136
ASP A1134
SER A1108
LEU A1098
 None
None
None
PEG  A1413 (-3.7A)
 1.06A 2cdqB-5i8gA:
undetectable		 2cdqB-5i8gA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihr PROBABLE
BETA-GALACTOSIDASE A

(Aspergillus
niger) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 SER A 756
TRP A 965
LEU A 683
GLU A 685
 None
 0.97A 2cdqB-5ihrA:
undetectable		 2cdqB-5ihrA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwz CELLULOSE-BINDING
FAMILY II

(Streptomyces
sp. SirexAA-E) 		PF02012
(BNR) 		4 SER A  51
ASP A  49
ARG A 109
GLU A  32
 None
 1.02A 2cdqB-5jwzA:
undetectable		 2cdqB-5jwzA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k66 NTA1P

(Saccharomyces
cerevisiae) 		PF00795
(CN_hydrolase) 		4 SER A  18
ARG A 457
LEU A 180
GLU A 214
 None
 1.08A 2cdqB-5k66A:
undetectable		 2cdqB-5k66A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kk5 CRISPR-ASSOCIATED
ENDONUCLEASE CPF1

(Acidaminococcus
sp. BV3L6) 		no annotation 4 SER A1209
ASP A1213
LEU A1185
GLU A1188
 None
 1.06A 2cdqB-5kk5A:
undetectable		 2cdqB-5kk5A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kvc HALOHYDRIN
DEHALOGENASE

(Agrobacterium
tumefaciens) 		PF13561
(adh_short_C2) 		4 SER A  34
ASP A  32
ARG A 107
GLU A  58
 None
 0.99A 2cdqB-5kvcA:
undetectable		 2cdqB-5kvcA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkz HISTONE
ACETYLTRANSFERASE
P300,HISTONE
ACETYLTRANSFERASE
P300

(Homo sapiens) 		PF00439
(Bromodomain)
PF06001
(DUF902)
PF08214
(HAT_KAT11) 		4 SER A1100
ASP A1098
SER A1072
LEU A1062
 None
 1.05A 2cdqB-5lkzA:
undetectable		 2cdqB-5lkzA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lox PEPTIDASE

(Pseudomonas
aeruginosa) 		no annotation 4 SER A  78
ASP A  81
SER A  72
LEU A  44
 None
 1.08A 2cdqB-5loxA:
undetectable		 2cdqB-5loxA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpk HISTONE
ACETYLTRANSFERASE
P300

(Homo sapiens) 		PF00439
(Bromodomain) 		4 SER A1100
ASP A1098
SER A1072
LEU A1062
 None
 1.11A 2cdqB-5lpkA:
undetectable		 2cdqB-5lpkA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m45 ACETONE CARBOXYLASE
BETA SUBUNIT

(Xanthobacter
autotrophicus) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		4 SER B 314
ASP B 316
SER B 470
LEU B 448
 None
 0.89A 2cdqB-5m45B:
undetectable		 2cdqB-5m45B:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mr8 E3 UBIQUITIN-PROTEIN
LIGASE TRIM33

(Homo sapiens) 		no annotation 4 SER A1004
ASP A1002
SER A 979
LEU A 970
 None
 1.08A 2cdqB-5mr8A:
undetectable		 2cdqB-5mr8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ttb SIDEROPHORE
YERSINIABACTIN

(Yersinia pestis) 		PF00550
(PP-binding) 		4 SER A  89
ARG A  90
LEU A  69
GLU A  73
 None
 1.11A 2cdqB-5ttbA:
undetectable		 2cdqB-5ttbA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4n FRUCTOSE-1

(Neisseria
gonorrhoeae) 		PF01116
(F_bP_aldolase) 		4 SER A 174
ASP A 177
SER A 107
LEU A 190
 None
 1.03A 2cdqB-5u4nA:
undetectable		 2cdqB-5u4nA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uvn PARAQUAT-INDUCIBLE
PROTEIN B

(Escherichia
coli) 		PF02470
(MlaD) 		4 SER A 249
ASP A 221
SER A 245
LEU A 170
 None
 1.04A 2cdqB-5uvnA:
undetectable		 2cdqB-5uvnA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uxi ALDEHYDE
DECARBONYLASE

(Nostoc
punctiforme) 		no annotation 4 SER A 212
ARG A 223
LEU A 224
GLU A 168
 None
 0.96A 2cdqB-5uxiA:
undetectable		 2cdqB-5uxiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0e CREB-BINDING PROTEIN

(Homo sapiens) 		no annotation 4 SER A1136
ASP A1134
SER A1108
LEU A1098
 None
 1.01A 2cdqB-5w0eA:
undetectable		 2cdqB-5w0eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xpg UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		no annotation 4 SER A 110
ARG A  17
LEU A  19
GLU A  23
 None
 0.97A 2cdqB-5xpgA:
undetectable		 2cdqB-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yew MITOFUSIN-1,MITOFUSI
N-1 FUSION PROTEIN

(Homo sapiens) 		no annotation 4 SER B 284
ASP B 240
ARG B 253
GLU B 316
 GDP  B 801 (-3.1A)
GDP  B 801 (-3.0A)
None
None
 1.10A 2cdqB-5yewB:
undetectable		 2cdqB-5yewB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculosis) 		no annotation 4 SER A  62
ARG A  64
LEU A  66
GLU A  70
 SER  A  62 ( 0.0A)
ARG  A  64 ( 0.6A)
LEU  A  66 ( 0.5A)
GLU  A  70 ( 0.6A)
 1.10A 2cdqB-6gefA:
undetectable		 2cdqB-6gefA:
undetectable