SIMILAR PATTERNS OF AMINO ACIDS FOR 2CDQ_A_SAMA1500_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dwa MYROSINASE MA1

(Sinapis alba) 		PF00232
(Glyco_hydro_1) 		4 ASP M 162
SER M 110
ARG M 111
GLU M 151
 None
SO4  M 925 ( 4.3A)
SO4  M 925 (-3.8A)
None
 0.65A 2cdqA-1dwaM:
1.9		 2cdqA-1dwaM:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz4 NAD-DEPENDENT MALIC
ENZYME

(Homo sapiens) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ILE A 135
ASP A 204
LEU A 234
GLU A 237
 None
 1.00A 2cdqA-1gz4A:
0.0		 2cdqA-1gz4A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1icp 12-OXOPHYTODIENOATE
REDUCTASE 1

(Solanum
lycopersicum) 		PF00724
(Oxidored_FMN) 		4 ILE A 165
ARG A 155
LEU A 157
GLU A 161
 None
 0.89A 2cdqA-1icpA:
1.0		 2cdqA-1icpA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k20 MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Streptococcus
gordonii) 		PF01368
(DHH)
PF02833
(DHHA2) 		4 ILE A  62
SER A  64
LEU A   5
GLU A  36
 None
 0.97A 2cdqA-1k20A:
0.4		 2cdqA-1k20A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oal SUPEROXIDE DISMUTASE

(Photobacterium
leiognathi) 		PF00080
(Sod_Cu) 		4 ILE A  46
ASP A  91
LEU A 112
GLU A 116
 None
ZN  A 152 (-2.2A)
None
None
 0.96A 2cdqA-1oalA:
undetectable		 2cdqA-1oalA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pca PROCARBOXYPEPTIDASE
A PCPA

(Sus scrofa) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		4 ILE A 193
SER A 194
ASP A  65
SER A  78
 None
 0.86A 2cdqA-1pcaA:
0.0		 2cdqA-1pcaA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pp1 P40 NUCLEOPROTEIN

(Borna disease
virus) 		PF06407
(BDV_P40) 		4 ILE X 136
ARG X 126
LEU X 128
GLU X 132
 None
 0.91A 2cdqA-1pp1X:
undetectable		 2cdqA-1pp1X:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1um8 ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT CLPX

(Helicobacter
pylori) 		PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 ILE A 273
SER A 271
ASP A 269
LEU A 192
 None
 0.90A 2cdqA-1um8A:
undetectable		 2cdqA-1um8A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcj PEROXISOMAL
BIFUNCTIONAL ENZYME

(Rattus
norvegicus) 		PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ILE A 320
SER A 297
ASP A 375
LEU A 461
 None
 0.95A 2cdqA-1zcjA:
2.1		 2cdqA-1zcjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN

(Homo sapiens;
Homo sapiens) 		PF07686
(V-set)
PF07686
(V-set) 		4 SER L 135
TRP L 109
SER H 134
LEU L 138
 None
 0.97A 2cdqA-2a9mL:
undetectable		 2cdqA-2a9mL:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ab4 TRNA PSEUDOURIDINE
SYNTHASE B

(Thermotoga
maritima) 		PF01472
(PUA)
PF01509
(TruB_N)
PF16198
(TruB_C_2) 		4 ASP A  81
ARG A 157
LEU A  75
GLU A  89
 C  B  11 ( 2.8A)
None
None
None
 0.92A 2cdqA-2ab4A:
undetectable		 2cdqA-2ab4A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 ILE B 466
ARG B 450
LEU B 431
GLU B 462
 None
 0.83A 2cdqA-2amcB:
1.2		 2cdqA-2amcB:
22.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2cdq ASPARTOKINASE

(Arabidopsis
thaliana) 		PF00696
(AA_kinase) 		8 ILE A 370
SER A 371
ASP A 387
TRP A 392
SER A 393
ARG A 394
LEU A 396
GLU A 400
 SAM  A1500 (-4.4A)
LYS  A 600 ( 3.3A)
SAM  A1500 (-4.7A)
SAM  A1500 (-3.7A)
SAM  A1500 (-2.6A)
SAM  A1500 (-3.7A)
SAM  A1500 (-4.1A)
SAM  A1500 (-3.8A)
 0.00A 2cdqA-2cdqA:
62.0		 2cdqA-2cdqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE

(Candida
albicans) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 ILE A 244
SER A 245
ASP A 218
LEU A 443
 None
 1.00A 2cdqA-2dkdA:
undetectable		 2cdqA-2dkdA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8l HYPOTHETICAL PROTEIN
LMO1582

(Listeria
monocytogenes) 		PF02384
(N6_Mtase) 		4 ILE A 122
SER A 121
ASP A 191
LEU A 110
 None
 0.95A 2cdqA-2f8lA:
undetectable		 2cdqA-2f8lA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fcw ALPHA-2-MACROGLOBULI
N
RECEPTOR-ASSOCIATED
PROTEIN
LOW-DENSITY
LIPOPROTEIN RECEPTOR

(Homo sapiens;
Homo sapiens) 		PF06401
(Alpha-2-MRAP_C)
PF00057
(Ldl_recept_a) 		4 ILE B 101
SER B 102
SER A 286
ARG A 285
 None
 0.94A 2cdqA-2fcwB:
undetectable		 2cdqA-2fcwB:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fyw CONSERVED
HYPOTHETICAL PROTEIN

(Streptococcus
pneumoniae) 		PF01784
(NIF3) 		4 ILE A 140
SER A 176
ASP A 198
LEU A 148
 None
 1.00A 2cdqA-2fywA:
undetectable		 2cdqA-2fywA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5g PUTATIVE LIPOPROTEIN

(Campylobacter
jejuni) 		PF04187
(Cofac_haem_bdg) 		4 ILE X 147
ARG X 200
LEU X 139
GLU X 143
 None
 1.01A 2cdqA-2g5gX:
undetectable		 2cdqA-2g5gX:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2t LOW AFFINITY
IMMUNOGLOBULIN
EPSILON FC RECEPTOR
(LYMPHOCYTE IGE
RECEPTOR)
(FC-EPSILON-RII)
(IMMUNOGLOBULIN
E-BINDING FACTOR)
(CD23 ANTIGEN)

(Homo sapiens) 		PF00059
(Lectin_C) 		4 ILE B 201
SER B 200
ASP B 283
LEU B 210
 None
 1.01A 2cdqA-2h2tB:
undetectable		 2cdqA-2h2tB:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2g DIENELACTONE
HYDROLASE

(Trichormus
variabilis) 		PF01738
(DLH) 		4 SER A  95
ARG A  96
LEU A  72
GLU A  76
 None
 0.82A 2cdqA-2o2gA:
undetectable		 2cdqA-2o2gA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ong 4S-LIMONENE SYNTHASE

(Mentha spicata) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ILE A 559
SER A 477
LEU A 484
GLU A 546
 None
 0.92A 2cdqA-2ongA:
undetectable		 2cdqA-2ongA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paa PHOSPHOGLYCERATE
KINASE, TESTIS
SPECIFIC

(Mus musculus) 		PF00162
(PGK) 		4 ILE A  46
SER A  45
ASP A 163
LEU A  59
 None
 0.96A 2cdqA-2paaA:
5.4		 2cdqA-2paaA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3r 12-OXOPHYTODIENOATE
REDUCTASE 1

(Arabidopsis
thaliana) 		PF00724
(Oxidored_FMN) 		4 ILE A 161
ARG A 151
LEU A 153
GLU A 157
 None
 0.64A 2cdqA-2q3rA:
undetectable		 2cdqA-2q3rA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r14 MORPHINONE REDUCTASE

(Pseudomonas
putida) 		PF00724
(Oxidored_FMN) 		4 ILE A 164
ARG A 154
LEU A 156
GLU A 160
 None
 0.72A 2cdqA-2r14A:
undetectable		 2cdqA-2r14A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhq PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Staphylococcus
haemolyticus) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 ILE B 475
ARG B 459
LEU B 440
GLU B 471
 None
 0.87A 2cdqA-2rhqB:
undetectable		 2cdqA-2rhqB:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf2 CATALASE

(Penicillium
janthinellum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 ILE A 486
SER A 487
SER A 450
LEU A 190
 None
 0.75A 2cdqA-2xf2A:
undetectable		 2cdqA-2xf2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A 380
SER A 379
ASP A 323
LEU A 374
 None
 1.01A 2cdqA-2xybA:
undetectable		 2cdqA-2xybA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
1, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ILE B  52
SER B  32
ASP B  30
LEU B  50
 None
NAG  A 801 (-2.9A)
NAG  A 801 ( 4.6A)
None
 0.91A 2cdqA-2z7xB:
undetectable		 2cdqA-2z7xB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2b SERINE
PALMITOYLTRANSFERASE

(Sphingobacterium
multivorum) 		PF00155
(Aminotran_1_2) 		4 ILE A 141
ASP A 143
SER A 269
LEU A 121
 None
 0.97A 2cdqA-3a2bA:
undetectable		 2cdqA-3a2bA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayh DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC9

(Schizosaccharomyces
pombe) 		PF03874
(RNA_pol_Rpb4) 		4 ILE A  90
ARG A 111
LEU A  82
GLU A  86
 None
 0.98A 2cdqA-3ayhA:
undetectable		 2cdqA-3ayhA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daq DIHYDRODIPICOLINATE
SYNTHASE

(Staphylococcus
aureus) 		PF00701
(DHDPS) 		4 ILE A  61
ARG A 268
LEU A  53
GLU A  57
 None
 0.88A 2cdqA-3daqA:
undetectable		 2cdqA-3daqA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7q INTEGRIN BETA-4

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A1326
SER A1325
SER A1232
LEU A1284
 None
 0.78A 2cdqA-3f7qA:
undetectable		 2cdqA-3f7qA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fju CARBOXYPEPTIDASE A1

(Homo sapiens) 		PF00246
(Peptidase_M14) 		4 ILE A 193
SER A 194
ASP A  65
SER A  78
 None
 0.84A 2cdqA-3fjuA:
undetectable		 2cdqA-3fjuA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fss HISTONE CHAPERONE
RTT106

(Saccharomyces
cerevisiae) 		PF08512
(Rtt106) 		4 ILE A 116
SER A 115
SER A  96
LEU A 119
 None
 0.86A 2cdqA-3fssA:
undetectable		 2cdqA-3fssA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2i ESTERASE

(Xanthomonas
oryzae) 		PF03583
(LIP) 		4 ILE A 149
SER A 146
LEU A 193
GLU A 196
 None
 0.78A 2cdqA-3h2iA:
undetectable		 2cdqA-3h2iA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6r DIHYDROOROTATE
DEHYDROGENASE
HOMOLOG,
MITOCHONDRIAL

(Plasmodium
falciparum) 		PF01180
(DHO_dh) 		4 ILE A 542
SER A 510
ASP A 513
LEU A 527
 None
 0.67A 2cdqA-3i6rA:
undetectable		 2cdqA-3i6rA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyp COMPLEMENT
DECAY-ACCELERATING
FACTOR

(Homo sapiens) 		PF00084
(Sushi) 		4 ILE F 142
TRP F 181
SER F 182
LEU F 185
 None
 1.00A 2cdqA-3iypF:
undetectable		 2cdqA-3iypF:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN

(Marinobacter
hydrocarbonoclasticus) 		PF04073
(tRNA_edit)
PF08668
(HDOD) 		4 ILE A 347
SER A 344
ASP A 343
ARG A  33
 None
 0.88A 2cdqA-3memA:
undetectable		 2cdqA-3memA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npf PUTATIVE
DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
ovatus) 		PF00877
(NLPC_P60) 		4 ILE A 179
SER A 178
ASP A 175
LEU A 307
 None
 0.89A 2cdqA-3npfA:
undetectable		 2cdqA-3npfA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o6n APL1

(Anopheles
gambiae) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 ILE A 412
SER A 389
ASP A 387
LEU A 410
 None
 1.01A 2cdqA-3o6nA:
undetectable		 2cdqA-3o6nA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja LEUCINE-RICH IMMUNE
MOLECULE 1

(Anopheles
gambiae) 		PF00560
(LRR_1) 		4 ILE A  71
SER A  72
ASP A  75
SER A  43
 None
 0.99A 2cdqA-3ojaA:
undetectable		 2cdqA-3ojaA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 ILE A 533
SER A 532
SER A 359
LEU A 507
 None
None
SO4  A 991 (-3.4A)
None
 0.96A 2cdqA-3opyA:
undetectable		 2cdqA-3opyA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si9 DIHYDRODIPICOLINATE
SYNTHASE

(Bartonella
henselae) 		PF00701
(DHDPS) 		4 ILE A  63
ARG A 272
LEU A  55
GLU A  59
 None
 0.90A 2cdqA-3si9A:
undetectable		 2cdqA-3si9A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sm9 METABOTROPIC
GLUTAMATE RECEPTOR 3

(Homo sapiens) 		PF01094
(ANF_receptor) 		4 ILE A 130
SER A 127
ASP A  77
SER A  84
 None
None
SO4  A 481 (-4.3A)
None
 0.96A 2cdqA-3sm9A:
undetectable		 2cdqA-3sm9A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sql GLYCOSYL HYDROLASE
FAMILY 3

(Synechococcus
sp. PCC 7002) 		PF00933
(Glyco_hydro_3) 		4 ILE A 244
ARG A 217
LEU A 218
GLU A 222
 None
 0.93A 2cdqA-3sqlA:
undetectable		 2cdqA-3sqlA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t9p MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Roseovarius sp.
TM1035) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 336
SER A 140
ARG A 156
LEU A 157
 None
 0.96A 2cdqA-3t9pA:
undetectable		 2cdqA-3t9pA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 ILE A 292
SER A 293
SER A 530
LEU A 527
 None
 0.96A 2cdqA-3zs6A:
undetectable		 2cdqA-3zs6A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ILE A 349
SER A 348
ASP A 429
LEU A 343
 None
 1.00A 2cdqA-3zz1A:
undetectable		 2cdqA-3zz1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab4 XENOBIOTIC REDUCTASE
B

(Pseudomonas
putida) 		PF00724
(Oxidored_FMN) 		4 ILE A 151
ARG A 141
LEU A 143
GLU A 147
 None
 0.73A 2cdqA-4ab4A:
undetectable		 2cdqA-4ab4A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc6 SERINE/THREONINE-PRO
TEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 228
TRP A 263
SER A 264
LEU A 271
 None
 0.99A 2cdqA-4bc6A:
undetectable		 2cdqA-4bc6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgu MALATE DEHYDROGENASE

(Haloferax
volcanii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ASP A 124
ARG A 138
LEU A 251
GLU A 254
 None
 0.92A 2cdqA-4bguA:
undetectable		 2cdqA-4bguA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF04054
(Not1) 		4 ILE A1912
SER A1910
SER A1977
LEU A1972
 None
 0.99A 2cdqA-4by6A:
undetectable		 2cdqA-4by6A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cng SPOU RRNA METHYLASE

(Sulfolobus
acidocaldarius) 		PF00588
(SpoU_methylase) 		4 ILE A 109
ARG A 112
LEU A 117
GLU A 121
 None
None
SAH  A1158 (-4.8A)
None
 0.70A 2cdqA-4cngA:
undetectable		 2cdqA-4cngA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6f UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF14730
(DUF4468) 		4 ILE A 104
ASP A 180
ARG A  75
GLU A 102
 None
 0.93A 2cdqA-4e6fA:
undetectable		 2cdqA-4e6fA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3l CIRCADIAN LOCOMOTER
OUTPUT CYCLES
PROTEIN KAPUT

(Mus musculus) 		PF00010
(HLH)
PF00989
(PAS)
PF14598
(PAS_11) 		4 ILE A 125
SER A 130
ASP A 128
LEU A 170
 None
 0.95A 2cdqA-4f3lA:
undetectable		 2cdqA-4f3lA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq2 NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 ILE M 238
SER M 253
SER M 275
LEU M 279
 None
 0.92A 2cdqA-4gq2M:
undetectable		 2cdqA-4gq2M:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq2 NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 SER M 253
ASP M 255
SER M 275
LEU M 279
 None
 0.75A 2cdqA-4gq2M:
undetectable		 2cdqA-4gq2M:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1x PHOSPHATE-BINDING
PROTEIN PSTS 2

(Streptococcus
pneumoniae) 		PF12849
(PBP_like_2) 		4 SER A 237
ARG A 238
LEU A 240
GLU A 244
 None
 0.71A 2cdqA-4h1xA:
undetectable		 2cdqA-4h1xA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hr1 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
abyssi virus 1) 		no annotation 4 ILE B  77
ARG B  63
LEU B  69
GLU B  73
 None
 0.98A 2cdqA-4hr1B:
0.4		 2cdqA-4hr1B:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hrv PUTATIVE LIPOPROTEIN
GNA1162

(Neisseria
meningitidis) 		PF05643
(DUF799) 		4 ILE A  38
SER A  37
ASP A 107
LEU A 136
 None
 0.77A 2cdqA-4hrvA:
undetectable		 2cdqA-4hrvA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iiv 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE

(Escherichia
coli) 		PF13561
(adh_short_C2) 		4 ILE A 238
SER A 237
ARG A 209
GLU A 215
 None
 0.75A 2cdqA-4iivA:
undetectable		 2cdqA-4iivA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4itu SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Xanthobacter
autotrophicus) 		PF13561
(adh_short_C2) 		4 SER A 123
ARG A 133
LEU A  85
GLU A  79
 None
 0.99A 2cdqA-4ituA:
undetectable		 2cdqA-4ituA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jsb ENOYL-COA HYDRATASE

(Thermobifida
fusca) 		PF00378
(ECH_1) 		4 ILE A 126
SER A 125
ASP A 145
LEU A 220
 None
 0.99A 2cdqA-4jsbA:
undetectable		 2cdqA-4jsbA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3x HEMAGGLUTININ HA1

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 ILE A  87
SER A 113
LEU A  66
GLU A  89
 None
 0.92A 2cdqA-4k3xA:
undetectable		 2cdqA-4k3xA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kms ACETOACETYL-COA
REDUCTASE

(Rickettsia
felis) 		PF13561
(adh_short_C2) 		4 ILE A 234
SER A 233
ARG A 205
GLU A 211
 None
 0.97A 2cdqA-4kmsA:
1.6		 2cdqA-4kmsA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt1 LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4

(Homo sapiens) 		PF01462
(LRRNT)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ILE A  64
SER A  44
ASP A  42
LEU A  62
 None
 0.99A 2cdqA-4kt1A:
undetectable		 2cdqA-4kt1A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kyi VIPD

(Legionella
pneumophila) 		PF01734
(Patatin) 		4 SER A  80
ARG A 222
LEU A 218
GLU A 253
 None
 0.93A 2cdqA-4kyiA:
undetectable		 2cdqA-4kyiA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lej VICILIN

(Pinus
koraiensis) 		PF00190
(Cupin_1) 		4 ILE A 324
SER A 323
ASP A 397
LEU A 180
 None
PO4  A 502 (-3.6A)
None
None
 0.87A 2cdqA-4lejA:
undetectable		 2cdqA-4lejA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mc5 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 ILE A  83
SER A 110
LEU A  61
GLU A  85
 None
 0.96A 2cdqA-4mc5A:
undetectable		 2cdqA-4mc5A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nky STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE

(Homo sapiens) 		PF00067
(p450) 		4 ILE A 344
SER A 345
ASP A 346
LEU A 454
 None
 0.89A 2cdqA-4nkyA:
undetectable		 2cdqA-4nkyA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxe LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4, LINKER,
VARIABLE LYMPHOCYTE
RECEPTOR B

(Eptatretus
burgeri;
Homo sapiens) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ILE A  64
SER A  44
ASP A  42
LEU A  62
 None
 0.97A 2cdqA-4qxeA:
undetectable		 2cdqA-4qxeA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxf LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ILE A  64
SER A  44
ASP A  42
LEU A  62
 None
 0.96A 2cdqA-4qxfA:
undetectable		 2cdqA-4qxfA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8g UNCONVENTIONAL
MYOSIN-IC

(Mus musculus) 		PF00612
(IQ)
PF06017
(Myosin_TH1) 		4 ILE E 932
SER E 933
SER E 940
LEU E 968
 None
 0.89A 2cdqA-4r8gE:
undetectable		 2cdqA-4r8gE:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uf4 CARBOXYPEPTIDASE A1

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		4 ILE A 303
SER A 304
ASP A 175
SER A 188
 None
 0.81A 2cdqA-4uf4A:
2.1		 2cdqA-4uf4A:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE

(Agrobacterium
tumefaciens) 		PF00701
(DHDPS) 		4 ILE A  68
ARG A 278
LEU A  60
GLU A  64
 None
 0.89A 2cdqA-4ur8A:
undetectable		 2cdqA-4ur8A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4usf STE20-LIKE
SERINE/THREONINE-PRO
TEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 226
TRP A 261
SER A 262
LEU A 269
 None
 0.98A 2cdqA-4usfA:
undetectable		 2cdqA-4usfA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wn5 HYPOXIA-INDUCIBLE
FACTOR 3-ALPHA

(Homo sapiens) 		PF14598
(PAS_11) 		4 ILE A 258
SER A 265
ASP A 268
SER A 310
 MVC  A 402 ( 4.8A)
None
None
None
 0.74A 2cdqA-4wn5A:
undetectable		 2cdqA-4wn5A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4s EXTRACELLULAR HEME
ACQUISITION
HEMOPHORE HASA

(Yersinia
pseudotuberculosis) 		PF06438
(HasA) 		4 ILE A  87
SER A 122
ASP A 120
GLU A  70
 None
 0.84A 2cdqA-4y4sA:
undetectable		 2cdqA-4y4sA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amq RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF04196
(Bunya_RdRp)
PF15518
(L_protein_N) 		4 ILE A1091
ARG A 818
LEU A1083
GLU A1087
 None
 0.89A 2cdqA-5amqA:
undetectable		 2cdqA-5amqA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Staphylococcus
aureus) 		PF13395
(HNH_4)
PF16592
(Cas9_REC) 		4 ILE A 283
ARG A 269
LEU A 275
GLU A 279
 None
 0.89A 2cdqA-5czzA:
1.9		 2cdqA-5czzA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dm4 METHYLTRANSFERASE
DOMAIN FAMILY

(Bacillus
pumilus) 		PF13489
(Methyltransf_23) 		4 ILE A   6
ARG A 162
LEU A 189
GLU A 193
 None
 0.81A 2cdqA-5dm4A:
undetectable		 2cdqA-5dm4A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epd GLYCEROL TRINITRATE
REDUCTASE

(Agrobacterium
tumefaciens) 		PF00724
(Oxidored_FMN) 		4 ILE A 154
ARG A 144
LEU A 146
GLU A 150
 None
 0.68A 2cdqA-5epdA:
undetectable		 2cdqA-5epdA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghf AMINOTRANSFERASE
CLASS-III

(Ochrobactrum
anthropi) 		PF00202
(Aminotran_3) 		4 ILE A 145
SER A 146
LEU A 210
GLU A 214
 None
 0.97A 2cdqA-5ghfA:
undetectable		 2cdqA-5ghfA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h04 BINARY ENTEROTOXIN
OF CLOSTRIDIUM
PERFRINGENS
COMPONENT A

(Clostridium
perfringens) 		PF03496
(ADPrib_exo_Tox) 		4 ILE A 280
SER A 281
ASP A 386
LEU A 384
 None
 1.00A 2cdqA-5h04A:
undetectable		 2cdqA-5h04A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4v GLUTAMATE--TRNA
LIGASE

(Xanthomonas
oryzae) 		no annotation 4 ILE A  73
ASP A 188
ARG A   4
GLU A  70
 None
 0.89A 2cdqA-5h4vA:
2.3		 2cdqA-5h4vA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		4 ILE A 671
SER A 647
ASP A 645
LEU A 669
 None
 1.00A 2cdqA-5hdhA:
undetectable		 2cdqA-5hdhA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i84 PHOSPHATE-BINDING
PROTEIN PSTS

(Xanthomonas
citri) 		PF12849
(PBP_like_2) 		4 ILE A  66
SER A  62
LEU A  83
GLU A  87
 PO4  A 404 (-4.2A)
None
None
None
 0.92A 2cdqA-5i84A:
undetectable		 2cdqA-5i84A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqw 4-AMINOBUTYRATE
TRANSAMINASE

(Pseudomonas) 		PF00202
(Aminotran_3) 		4 ILE A 147
SER A 148
LEU A 211
GLU A 215
 None
 0.96A 2cdqA-5kqwA:
undetectable		 2cdqA-5kqwA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lgx PENTAERYTHRITOL
TETRANITRATE
REDUCTASE

(Enterobacter
cloacae) 		PF00724
(Oxidored_FMN) 		4 ILE A 159
ARG A 149
LEU A 151
GLU A 155
 None
 0.87A 2cdqA-5lgxA:
undetectable		 2cdqA-5lgxA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n2i REDUCED COENZYME
F420:NADP
OXIDOREDUCTASE

(Thermobifida
fusca) 		PF03807
(F420_oxidored) 		4 ILE A  22
SER A  21
ASP A  82
LEU A 186
 None
 0.86A 2cdqA-5n2iA:
undetectable		 2cdqA-5n2iA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tcb PELA

(Pseudomonas
aeruginosa) 		PF03537
(Glyco_hydro_114) 		4 ILE A 220
SER A 219
LEU A 277
GLU A 280
 None
 0.98A 2cdqA-5tcbA:
undetectable		 2cdqA-5tcbA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txv ATP-DEPENDENT
PROTEASE ATPASE
SUBUNIT HSLU

(Escherichia
coli) 		PF00004
(AAA)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 ILE A 351
SER A 350
LEU A 399
GLU A 400
 None
 0.97A 2cdqA-5txvA:
undetectable		 2cdqA-5txvA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uao TRYPTOPHANE-5-HALOGE
NASE

(Microbispora
sp. ATCC
PTA-5024) 		PF04820
(Trp_halogenase) 		4 ILE A  29
SER A 376
ASP A 379
LEU A 373
 None
 0.92A 2cdqA-5uaoA:
undetectable		 2cdqA-5uaoA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wva SHORT-CHAIN
DEHYDROGENASE

(Serratia
marcescens) 		no annotation 4 ILE A 243
SER A 242
ARG A 214
GLU A 220
 None
 0.67A 2cdqA-5wvaA:
undetectable		 2cdqA-5wvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5y PROBABLE ATP-BINDING
COMPONENT OF ABC
TRANSPORTER

(Pseudomonas
aeruginosa) 		no annotation 4 ILE B 224
SER B 223
ASP B 220
LEU B 201
 None
 0.84A 2cdqA-5x5yB:
undetectable		 2cdqA-5x5yB:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgj PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM

(Homo sapiens) 		no annotation 4 ILE A 393
ASP A 478
SER A 481
LEU A 436
 None
 0.99A 2cdqA-5xgjA:
undetectable		 2cdqA-5xgjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ao9 BACTERIO-RHODOPSIN/G
UANYLYL CYCLASE 1
FUSION PROTEIN

(Blastocladiella
emersonii) 		no annotation 4 ILE A 542
ASP A 501
ARG A 467
GLU A 540
 None
 0.96A 2cdqA-6ao9A:
3.9		 2cdqA-6ao9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e12 -

(-) 		no annotation 4 ILE A  31
SER A  30
LEU A 156
GLU A 140
 OLA  A 301 (-4.6A)
None
None
OLA  A 301 (-3.4A)
 0.74A 2cdqA-6e12A:
undetectable		 2cdqA-6e12A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fao GLYCOSIDE HYDROLASE
FAMILY 6

(metagenome) 		no annotation 4 ILE A 185
SER A 186
ASP A 157
LEU A 173
 None
 0.90A 2cdqA-6faoA:
undetectable		 2cdqA-6faoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculosis) 		no annotation 4 SER A  62
ARG A  64
LEU A  66
GLU A  70
 SER  A  62 ( 0.0A)
ARG  A  64 ( 0.6A)
LEU  A  66 ( 0.5A)
GLU  A  70 ( 0.6A)
 0.99A 2cdqA-6gefA:
1.3		 2cdqA-6gefA:
undetectable