SIMILAR PATTERNS OF AMINO ACIDS FOR 2BYO_A_LNLA1216_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		4 LEU B 287
ILE B 305
LEU B 306
SER B 307
 None
 0.96A 2byoA-1cqiB:
0.0		 2byoA-1cqiB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dcp DCOH

(Rattus
norvegicus) 		PF01329
(Pterin_4a) 		4 LEU A  17
ILE A  34
LEU A  77
SER A  78
 None
 0.98A 2byoA-1dcpA:
undetectable		 2byoA-1dcpA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF03971
(IDH) 		4 LEU A 663
ILE A  25
LEU A  23
SER A  21
 None
 0.96A 2byoA-1j1wA:
0.0		 2byoA-1j1wA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION

(Saccharomyces
cerevisiae) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 311
ILE A 153
LEU A 157
SER A 155
 None
 0.98A 2byoA-1q1nA:
0.0		 2byoA-1q1nA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkv HOMOSERINE KINASE

(Pseudomonas
aeruginosa) 		PF12710
(HAD) 		4 LEU A  12
ILE A  88
LEU A  89
SER A  90
 None
None
None
PO4  A 320 (-3.0A)
 0.91A 2byoA-1rkvA:
0.0		 2byoA-1rkvA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sfx CONSERVED
HYPOTHETICAL PROTEIN
AF2008

(Archaeoglobus
fulgidus) 		PF01978
(TrmB) 		4 LEU A  54
ILE A  24
LEU A  27
ARG A  31
 None
 0.88A 2byoA-1sfxA:
0.0		 2byoA-1sfxA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sg9 HEMK PROTEIN

(Thermotoga
maritima) 		PF05175
(MTS) 		4 LEU A 181
ILE A 194
LEU A 195
SER A 196
 None
 0.86A 2byoA-1sg9A:
0.0		 2byoA-1sg9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u02 TREHALOSE-6-PHOSPHAT
E PHOSPHATASE
RELATED PROTEIN

(Thermoplasma
acidophilum) 		PF02358
(Trehalose_PPase) 		5 LEU A  35
ILE A   4
LEU A   3
SER A   2
ARG A 172
 None
 1.42A 2byoA-1u02A:
0.0		 2byoA-1u02A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ud9 DNA POLYMERASE
SLIDING CLAMP A

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A  18
ILE A  47
LEU A  46
SER A  45
 None
 0.91A 2byoA-1ud9A:
1.2		 2byoA-1ud9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wra TEICHOIC ACID
PHOSPHORYLCHOLINE
ESTERASE/CHOLINE
BINDING PROTEIN E
(CBPE)

(Streptococcus
pneumoniae) 		PF00753
(Lactamase_B) 		4 LEU A 295
ILE A 266
LEU A 269
SER A 270
 None
 1.00A 2byoA-1wraA:
undetectable		 2byoA-1wraA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Lactococcus
lactis) 		PF13393
(tRNA-synt_His) 		4 LEU A 131
ILE A 143
LEU A 144
SER A 145
 None
 1.00A 2byoA-1z7mA:
undetectable		 2byoA-1z7mA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dnc PYRUVATE
DEHYDROGENASE
PROTEIN X COMPONENT

(Homo sapiens) 		PF00364
(Biotin_lipoyl) 		4 LEU A  53
ILE A  79
LEU A  78
SER A  77
 None
 0.66A 2byoA-2dncA:
undetectable		 2byoA-2dncA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eqx KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 4

(Homo sapiens) 		PF07707
(BACK) 		4 LEU A 207
ILE A 211
LEU A 247
SER A 246
 None
 0.80A 2byoA-2eqxA:
undetectable		 2byoA-2eqxA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8t ARGONAUTE PROTEIN

(Aquifex
aeolicus) 		PF02171
(Piwi) 		4 LEU A 407
ILE A 395
LEU A 394
SER A 393
 None
 0.80A 2byoA-2f8tA:
undetectable		 2byoA-2f8tA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i76 HYPOTHETICAL PROTEIN

(Thermotoga
maritima) 		PF10728
(DUF2520) 		4 LEU A  16
ILE A  28
LEU A  29
SER A  30
 None
None
None
NDP  A 301 (-2.7A)
 1.00A 2byoA-2i76A:
undetectable		 2byoA-2i76A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ijx DNA POLYMERASE
SLIDING CLAMP A

(Sulfolobus
solfataricus) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A  18
ILE A  47
LEU A  46
SER A  45
 None
 0.78A 2byoA-2ijxA:
undetectable		 2byoA-2ijxA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjf L-LYSINE EPSILON
AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00202
(Aminotran_3) 		4 LEU A  47
ILE A 412
LEU A 414
ARG A 422
 None
 0.98A 2byoA-2jjfA:
undetectable		 2byoA-2jjfA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE

(Acinetobacter
baylyi) 		PF13420
(Acetyltransf_4) 		4 LEU A  73
ILE A  27
LEU A  28
ARG A  44
 None
None
ACT  A1183 ( 4.5A)
ACT  A1183 ( 3.8A)
 0.93A 2byoA-2jlmA:
undetectable		 2byoA-2jlmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p18 GLYOXALASE II

(Leishmania
infantum) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 LEU A  88
ILE A  72
LEU A  73
SER A  74
 None
 0.77A 2byoA-2p18A:
undetectable		 2byoA-2p18A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pgg RNA-DIRECTED RNA
POLYMERASE

(Infectious
bursal disease
virus) 		PF04197
(Birna_RdRp) 		4 LEU A 254
ILE A 252
LEU A 346
SER A 342
 None
 1.00A 2byoA-2pggA:
undetectable		 2byoA-2pggA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsx EUKARYOTIC
INITIATION FACTOR 4F
SUBUNIT P150

(Saccharomyces
cerevisiae) 		PF02854
(MIF4G) 		4 LEU E 617
ILE E 629
LEU E 630
SER E 627
 None
 0.99A 2byoA-2vsxE:
undetectable		 2byoA-2vsxE:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vug PAB1020

(Pyrococcus
abyssi) 		PF09414
(RNA_ligase) 		5 LEU A  77
ILE A 218
LEU A 221
SER A 222
ARG A 226
 None
 1.44A 2byoA-2vugA:
undetectable		 2byoA-2vugA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1k PUTATIVE SORTASE

(Streptococcus
pneumoniae) 		PF04203
(Sortase) 		4 LEU A  98
ILE A 141
SER A 139
ARG A 138
 None
 0.89A 2byoA-2w1kA:
undetectable		 2byoA-2w1kA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3af5 PUTATIVE
UNCHARACTERIZED
PROTEIN PH1404

(Pyrococcus
horikoshii) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		4 LEU A 412
ILE A 546
LEU A 427
SER A 544
 None
 0.86A 2byoA-3af5A:
undetectable		 2byoA-3af5A:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajf NON-STRUCTURAL
PROTEIN 3

(Rice hoja
blanca
tenuivirus) 		PF05310
(Tenui_NS3) 		4 LEU A  23
ILE A  37
LEU A  40
SER A  41
 None
 0.91A 2byoA-3ajfA:
undetectable		 2byoA-3ajfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ci0 PSEUDOPILIN GSPK

(Escherichia
coli) 		PF03934
(T2SSK) 		4 LEU K  55
ILE K 297
LEU K 296
SER K 295
 None
 0.82A 2byoA-3ci0K:
2.6		 2byoA-3ci0K:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8x PUTATIVE
NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E

(Bacillus
halodurans) 		PF13460
(NAD_binding_10) 		4 LEU A 200
ILE A 174
LEU A 152
SER A 153
 None
None
NAP  A 500 (-3.8A)
None
 0.97A 2byoA-3e8xA:
undetectable		 2byoA-3e8xA:
26.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ef1 RNA POLYMERASE II
SUBUNIT A C-TERMINAL
DOMAIN PHOSPHATASE

(Schizosaccharomyces
pombe) 		PF03031
(NIF)
PF12738
(PTCB-BRCT) 		4 LEU A 282
ILE A 168
LEU A 167
SER A 166
 None
 0.93A 2byoA-3ef1A:
undetectable		 2byoA-3ef1A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3es5 PUTATIVE CAPSID
PROTEIN

(Penicillium
stoloniferum
virus F) 		no annotation 4 LEU A 301
ILE A 217
LEU A 214
SER A 213
 None
 0.82A 2byoA-3es5A:
undetectable		 2byoA-3es5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0n UNCHARACTERIZED
PROTEIN DUF1470

(Jannaschia sp.
CCS1) 		PF07336
(ABATE)
PF11706
(zf-CGNR) 		4 LEU A  15
ILE A  73
LEU A  76
SER A  77
 None
 0.93A 2byoA-3h0nA:
undetectable		 2byoA-3h0nA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN

(Pseudomonas
protegens) 		PF13407
(Peripla_BP_4) 		4 LEU A  57
ILE A 126
LEU A 129
SER A 130
 None
 0.85A 2byoA-3h75A:
undetectable		 2byoA-3h75A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h90 FERROUS-IRON EFFLUX
PUMP FIEF

(Escherichia
coli) 		PF01545
(Cation_efflux)
PF16916
(ZT_dimer) 		4 LEU A  47
ILE A  50
LEU A  54
SER A  53
 None
 0.98A 2byoA-3h90A:
undetectable		 2byoA-3h90A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1w PROTEIN PRGH

(Salmonella
enterica) 		PF09480
(PrgH) 		4 ILE A  82
LEU A  84
SER A  96
ARG A  95
 None
 0.91A 2byoA-3j1wA:
undetectable		 2byoA-3j1wA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9y 1,25-DIHYDROXYVITAMI
N D(3)
24-HYDROXYLASE,
MITOCHONDRIAL

(Rattus
norvegicus) 		PF00067
(p450) 		4 LEU A  86
ILE A  73
LEU A  70
SER A  69
 None
None
CM5  A 517 ( 4.6A)
None
 0.87A 2byoA-3k9yA:
undetectable		 2byoA-3k9yA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kts GLYCEROL UPTAKE
OPERON
ANTITERMINATOR
REGULATORY PROTEIN

(Listeria
monocytogenes) 		PF04309
(G3P_antiterm) 		4 LEU A  75
ILE A  84
SER A  86
ARG A 105
 None
None
None
UNL  A 191 ( 4.3A)
 0.93A 2byoA-3ktsA:
undetectable		 2byoA-3ktsA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8y PHOSPHOPENTOMUTASE

(Bacillus cereus) 		PF01676
(Metalloenzyme) 		4 LEU A 136
ILE A 150
LEU A 149
SER A 148
 None
 1.00A 2byoA-3m8yA:
undetectable		 2byoA-3m8yA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mca ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN

(Schizosaccharomyces
pombe) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3) 		4 LEU A 571
ILE A 484
LEU A 485
SER A 486
 None
 0.93A 2byoA-3mcaA:
undetectable		 2byoA-3mcaA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqn CATABOLITE CONTROL
PROTEIN A

(Bacillus
subtilis) 		PF00356
(LacI)
PF13377
(Peripla_BP_3) 		4 LEU A 234
ILE A 244
LEU A 245
SER A 246
 None
 0.97A 2byoA-3oqnA:
undetectable		 2byoA-3oqnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psq HYPOTHETICAL
EXPORTED PROTEIN

(Streptococcus
pyogenes) 		PF04203
(Sortase) 		4 LEU A  71
ILE A 123
LEU A 122
SER A 121
 None
 0.82A 2byoA-3psqA:
undetectable		 2byoA-3psqA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q5e ATLASTIN-1

(Homo sapiens) 		PF02263
(GBP) 		4 LEU A 304
ILE A 213
LEU A 212
SER A 211
 None
 0.96A 2byoA-3q5eA:
undetectable		 2byoA-3q5eA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpt TRANSCRIPTIONAL
REGULATOR SLYA

(Salmonella
enterica) 		PF01047
(MarR) 		4 LEU A  12
ILE A  15
LEU A  19
ARG A  23
 None
 0.92A 2byoA-3qptA:
undetectable		 2byoA-3qptA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rht (GATASE1)-LIKE
PROTEIN

(Planctopirus
limnophila) 		PF07090
(GATase1_like) 		4 LEU A 248
ILE A  52
LEU A  53
SER A  54
 None
None
None
CA  A 257 ( 4.0A)
 0.90A 2byoA-3rhtA:
undetectable		 2byoA-3rhtA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdo NITRILOTRIACETATE
MONOOXYGENASE

(Burkholderia
pseudomallei) 		PF00296
(Bac_luciferase) 		4 LEU A 300
ILE A 336
LEU A 339
ARG A 343
 None
 0.91A 2byoA-3sdoA:
undetectable		 2byoA-3sdoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umm PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE

(Salmonella
enterica) 		PF02769
(AIRS_C)
PF13507
(GATase_5) 		4 LEU A 508
ILE A 530
LEU A 531
SER A 532
 None
 0.83A 2byoA-3ummA:
undetectable		 2byoA-3ummA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wq4 BETA-PRIMEVEROSIDASE

(Camellia
sinensis) 		PF00232
(Glyco_hydro_1) 		4 LEU A 102
ILE A 149
LEU A 145
SER A 146
 None
 0.93A 2byoA-3wq4A:
undetectable		 2byoA-3wq4A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zoq URACIL-DNA
GLYCOSYLASE

(Bacillus
subtilis) 		PF03167
(UDG) 		4 ILE A 149
LEU A 152
SER A 153
ARG A 155
 None
 0.76A 2byoA-3zoqA:
undetectable		 2byoA-3zoqA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab5 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Neisseria
meningitidis) 		PF03466
(LysR_substrate) 		4 LEU A 179
ILE A 240
LEU A 195
ARG A 221
 None
 0.72A 2byoA-4ab5A:
undetectable		 2byoA-4ab5A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4au2 SERPIN PEPTIDASE
INHIBITOR, CLADE H
(HEAT SHOCK PROTEIN
47), MEMBER 1,
(COLLAGEN BINDING
PROTEIN 1)

(Canis lupus) 		PF00079
(Serpin) 		4 LEU A 290
ILE A 268
LEU A 267
SER A 266
 None
 0.84A 2byoA-4au2A:
1.1		 2byoA-4au2A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8w GDP-L-FUCOSE
SYNTHASE

(Homo sapiens) 		PF01370
(Epimerase) 		4 ILE A 241
LEU A 289
SER A 287
ARG A 290
 None
 0.97A 2byoA-4b8wA:
undetectable		 2byoA-4b8wA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bnd ALPHA-PHOSPHOGLUCOMU
TASE

(Lactococcus
lactis) 		PF03332
(PMM) 		4 LEU B 200
ILE B   4
LEU B   5
SER B   6
 None
 0.83A 2byoA-4bndB:
undetectable		 2byoA-4bndB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bsj VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 3

(Homo sapiens) 		no annotation 4 LEU A 443
ILE A 523
SER A 439
ARG A 437
 None
 1.00A 2byoA-4bsjA:
undetectable		 2byoA-4bsjA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU A1313
ILE A1498
LEU A1262
SER A1496
 None
 1.00A 2byoA-4c3hA:
undetectable		 2byoA-4c3hA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4co6 NUCLEOPROTEIN

(Nipah
henipavirus) 		PF00973
(Paramyxo_ncap) 		4 LEU A  76
ILE A 172
LEU A 175
ARG A 218
 None
 0.93A 2byoA-4co6A:
undetectable		 2byoA-4co6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d3d IMINE REDUCTASE

(Bacillus cereus) 		PF03446
(NAD_binding_2) 		4 LEU A 168
ILE A  83
LEU A  84
SER A  85
 None
 0.79A 2byoA-4d3dA:
undetectable		 2byoA-4d3dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7w SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		4 LEU A 197
ILE A 145
LEU A 146
SER A 147
 None
 0.94A 2byoA-4d7wA:
undetectable		 2byoA-4d7wA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ehi BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH

(Campylobacter
jejuni) 		PF01808
(AICARFT_IMPCHas)
PF02142
(MGS) 		4 LEU A  20
ILE A  27
LEU A  28
SER A  29
 None
 0.64A 2byoA-4ehiA:
undetectable		 2byoA-4ehiA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4h GLUTAMINE DEPENDENT
NAD+ SYNTHETASE

(Burkholderia
thailandensis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		4 LEU A  71
ILE A 118
LEU A 117
SER A 116
 None
 0.83A 2byoA-4f4hA:
1.1		 2byoA-4f4hA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h17 HYDROLASE,
ISOCHORISMATASE
FAMILY

(Pseudomonas
putida) 		PF00857
(Isochorismatase) 		4 LEU A 113
ILE A  66
LEU A  25
SER A  24
 None
 0.72A 2byoA-4h17A:
undetectable		 2byoA-4h17A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3s GLUTAMINE-TRNA
LIGASE

(Saccharomyces
cerevisiae) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C)
PF04557
(tRNA_synt_1c_R2) 		4 LEU A 504
ILE A 501
LEU A 496
SER A 497
 None
ACT  A 914 ( 4.1A)
None
None
 0.99A 2byoA-4h3sA:
undetectable		 2byoA-4h3sA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4q BEL-BETA TREFOIL

(Boletus edulis) 		no annotation 4 LEU A 118
ILE A  24
SER A  26
ARG A  27
 None
None
None
GOL  A 201 (-4.0A)
 0.91A 2byoA-4i4qA:
undetectable		 2byoA-4i4qA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4s BEL BETA-TREFOIL

(Boletus edulis) 		no annotation 4 LEU A 118
ILE A  24
SER A  26
ARG A  27
 None
None
None
GOL  A 203 (-3.9A)
 0.95A 2byoA-4i4sA:
undetectable		 2byoA-4i4sA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE

(Gadus morhua) 		PF03167
(UDG) 		4 ILE A 230
LEU A 233
SER A 234
ARG A 237
 None
 0.75A 2byoA-4lylA:
undetectable		 2byoA-4lylA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE

(Gadus morhua) 		PF03167
(UDG) 		4 LEU A 244
LEU A 233
SER A 234
ARG A 237
 None
 0.99A 2byoA-4lylA:
undetectable		 2byoA-4lylA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mu6 KINECTIN 1 (KINESIN
RECEPTOR)

(Legionella
pneumophila) 		no annotation 4 LEU A 267
ILE A  36
LEU A  37
SER A  38
 None
 0.99A 2byoA-4mu6A:
undetectable		 2byoA-4mu6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mz0 CURL

(Moorea
producens) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A 848
ILE A 813
LEU A 812
SER A 811
 None
 0.92A 2byoA-4mz0A:
undetectable		 2byoA-4mz0A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nhy 2-OXOGLUTARATE AND
IRON-DEPENDENT
OXYGENASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4) 		4 LEU A 104
ILE A 233
LEU A 170
SER A 232
 None
None
None
PD2  A 603 (-3.1A)
 0.99A 2byoA-4nhyA:
undetectable		 2byoA-4nhyA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onz PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
ovatus) 		PF04041
(Glyco_hydro_130) 		4 LEU A 239
ILE A 204
LEU A 205
ARG A 276
 None
 0.98A 2byoA-4onzA:
1.2		 2byoA-4onzA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0m MCYG PROTEIN

(Microcystis
aeruginosa) 		no annotation 4 LEU B 116
ILE B 128
LEU B 129
SER B 130
 None
 0.97A 2byoA-4r0mB:
undetectable		 2byoA-4r0mB:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8f VACUOLAR
AMINOPEPTIDASE 1

(Saccharomyces
cerevisiae) 		PF02127
(Peptidase_M18) 		4 LEU A 310
ILE A 337
LEU A 338
SER A 339
 None
 0.98A 2byoA-4r8fA:
undetectable		 2byoA-4r8fA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcw SLIT AND NTRK-LIKE
PROTEIN 1

(Homo sapiens) 		PF13855
(LRR_8) 		4 LEU A 552
ILE A 524
LEU A 501
SER A 500
 None
 0.98A 2byoA-4rcwA:
undetectable		 2byoA-4rcwA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rhb LPS-ASSEMBLY PROTEIN
LPTD

(Escherichia
coli) 		PF04453
(OstA_C) 		4 LEU A 540
ILE A 582
LEU A 606
SER A 605
 None
 1.00A 2byoA-4rhbA:
2.6		 2byoA-4rhbA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u14 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus T4;
Rattus
norvegicus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 LEU A 106
ILE A 495
LEU A 496
SER A 493
 None
 0.94A 2byoA-4u14A:
undetectable		 2byoA-4u14A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase) 		4 LEU A 473
ILE A 317
LEU A 370
ARG A 373
 None
 0.98A 2byoA-4u3tA:
undetectable		 2byoA-4u3tA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w7g DYNEIN LIGHT
INTERMEDIATE CHAIN

(Chaetomium
thermophilum) 		PF05783
(DLIC) 		4 LEU A 279
ILE A 269
LEU A 268
SER A 267
 None
 0.84A 2byoA-4w7gA:
undetectable		 2byoA-4w7gA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xpz RNA POLYMERASE II
SUBUNIT A C-TERMINAL
DOMAIN PHOSPHATASE

(Schizosaccharomyces
pombe) 		PF03031
(NIF)
PF12738
(PTCB-BRCT) 		4 LEU A 282
ILE A 168
LEU A 167
SER A 166
 None
 0.91A 2byoA-4xpzA:
undetectable		 2byoA-4xpzA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yf6 BETA-CARBONIC
ANHYDRASE 1

(Mycobacterium
tuberculosis) 		PF00484
(Pro_CA) 		4 LEU A  71
ILE A 134
LEU A 131
SER A 130
 None
 0.82A 2byoA-4yf6A:
undetectable		 2byoA-4yf6A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqi D-ALANINE--D-ALANINE
LIGASE

(Yersinia pestis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 LEU A 242
ILE A 192
LEU A 193
ARG A 300
 None
 0.99A 2byoA-4zqiA:
undetectable		 2byoA-4zqiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c3u L-SERINE
AMMONIA-LYASE

(Rhizomucor
miehei) 		PF00291
(PALP) 		4 ILE A  98
LEU A 119
SER A 117
ARG A 113
 None
 0.99A 2byoA-5c3uA:
undetectable		 2byoA-5c3uA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cvi SLOR

(Streptococcus
mutans) 		PF01325
(Fe_dep_repress)
PF02742
(Fe_dep_repr_C)
PF04023
(FeoA) 		4 ILE A  12
LEU A  15
SER A  16
ARG A  18
 None
 0.86A 2byoA-5cviA:
undetectable		 2byoA-5cviA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fd5 FERRIC UPTAKE
REGULATION PROTEIN

(Rhizobium
leguminosarum) 		PF01475
(FUR) 		4 LEU A 130
ILE A 110
LEU A 113
ARG A 116
 None
 0.88A 2byoA-5fd5A:
undetectable		 2byoA-5fd5A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz SPINDLE POLE BODY
COMPONENT SPC97

(Saccharomyces
cerevisiae) 		PF04130
(Spc97_Spc98) 		4 ILE A 363
LEU A 361
SER A 360
ARG A 358
 None
 0.82A 2byoA-5flzA:
undetectable		 2byoA-5flzA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gn5 GLYCEROL KINASE

(Trypanosoma
brucei) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		5 LEU A 429
ILE A 432
LEU A 436
SER A 435
ARG A 493
 None
 1.48A 2byoA-5gn5A:
undetectable		 2byoA-5gn5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7w VENOM
5'-NUCLEOTIDASE

(Naja atra) 		no annotation 4 LEU A 131
ILE A 139
LEU A 140
SER A 141
 None
 0.97A 2byoA-5h7wA:
undetectable		 2byoA-5h7wA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		4 LEU A 474
ILE A 422
LEU A 420
SER A 397
 None
 0.88A 2byoA-5hdhA:
undetectable		 2byoA-5hdhA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j3p TYROSYL-DNA
PHOSPHODIESTERASE 2

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		4 LEU A 140
ILE A 117
LEU A 116
SER A 115
 None
 0.93A 2byoA-5j3pA:
undetectable		 2byoA-5j3pA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j4a IMMUNITY PROTEIN
CDII

(Burkholderia
pseudomallei) 		no annotation 4 ILE B  66
LEU B  64
SER B  62
ARG B 103
 None
 0.98A 2byoA-5j4aB:
undetectable		 2byoA-5j4aB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpe SERINE/THREONINE-PRO
TEIN PHOSPHATASE

(Candida
albicans) 		PF00149
(Metallophos)
PF16891
(STPPase_N) 		5 LEU A 366
ILE A 326
LEU A 217
SER A 216
ARG A 352
 None
 1.35A 2byoA-5jpeA:
undetectable		 2byoA-5jpeA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 LEU B 236
ILE B 249
LEU B 250
SER B 251
 None
 0.83A 2byoA-5kohB:
undetectable		 2byoA-5kohB:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4a INTRAFLAGELLAR
TRANSPORT PROTEIN 80

(Chlamydomonas
reinhardtii) 		no annotation 4 LEU A 173
ILE A 130
LEU A 119
SER A 132
 None
 0.95A 2byoA-5n4aA:
undetectable		 2byoA-5n4aA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM2

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 LEU 2 268
LEU 2 242
SER 2 241
ARG 2 230
 None
 0.78A 2byoA-5udb2:
undetectable		 2byoA-5udb2:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj8 ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Homo sapiens) 		PF07034
(ORC3_N) 		4 ILE A 152
LEU A 200
SER A 201
ARG A 204
 None
 0.91A 2byoA-5uj8A:
undetectable		 2byoA-5uj8A:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v0r UBIQUITIN-CONJUGATIN
G ENZYME

(Naegleria
fowleri) 		PF00179
(UQ_con) 		4 LEU A  68
ILE A 120
LEU A 121
SER A 119
 None
 0.98A 2byoA-5v0rA:
undetectable		 2byoA-5v0rA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vl1 LYSINE--TRNA LIGASE

(Mycobacterium
ulcerans) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 ILE A  92
LEU A 102
SER A 101
ARG A  99
 None
 0.95A 2byoA-5vl1A:
1.4		 2byoA-5vl1A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wxi EARP

(Neisseria
meningitidis) 		no annotation 4 LEU A  27
ILE A 152
LEU A 151
SER A 366
 None
 0.87A 2byoA-5wxiA:
undetectable		 2byoA-5wxiA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y1a -

(-) 		no annotation 4 LEU A  73
ILE A 190
LEU A 191
SER A 192
 None
 0.93A 2byoA-5y1aA:
0.6		 2byoA-5y1aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axg RAS GUANYL-RELEASING
PROTEIN 4

(Homo sapiens) 		no annotation 4 ILE A 422
LEU A 425
SER A 426
ARG A 429
 None
 0.93A 2byoA-6axgA:
undetectable		 2byoA-6axgA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dm8 -

(-) 		no annotation 4 LEU A 248
ILE A 163
LEU A 160
SER A 159
 6AK  A 401 (-4.3A)
None
None
None
 0.88A 2byoA-6dm8A:
undetectable		 2byoA-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3

(Homo sapiens) 		no annotation 4 LEU A 679
ILE A 616
LEU A 605
SER A 618
 None
 0.96A 2byoA-6en4A:
undetectable		 2byoA-6en4A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC8

(Saccharomyces
cerevisiae) 		no annotation 4 ILE G   3
LEU G   4
SER G   5
ARG G  73
 None
 0.84A 2byoA-6f42G:
undetectable		 2byoA-6f42G:
16.67