SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXP_A_P1ZA3001_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bt4 | PHOSPHOSERINEAMINOTRANSFERASE (Bacilluscirculans) |
PF00266(Aminotran_5) | 5 | LEU A 58LEU A 62LEU A 261ILE A 255SER A 180 | None | 0.99A | 2bxpA-1bt4A:undetectable | 2bxpA-1bt4A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cbk | PROTEIN(7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE) (Haemophilusinfluenzae) |
PF01288(HPPK) | 5 | LEU A 94LEU A 19LEU A 23ILE A 26ALA A 7 | None | 1.12A | 2bxpA-1cbkA:undetectable | 2bxpA-1cbkA:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hbr | PROTEIN (HEMOGLOBIND) (Gallus gallus) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ALA A 79ALA A 65 | NoneNoneHEM A 142 (-3.3A)NoneHEM A 142 ( 3.9A) | 0.90A | 2bxpA-1hbrA:undetectable | 2bxpA-1hbrA:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ipa | RNA 2'-O-RIBOSEMETHYLTRANSFERASE (Thermusthermophilus) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 5 | LEU A 74LEU A 96ALA A 34ILE A 37ALA A 67 | None | 1.03A | 2bxpA-1ipaA:undetectable | 2bxpA-1ipaA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iuq | GLYCEROL-3-PHOSPHATEACYLTRANSFERASE (Cucurbitamoschata) |
PF01553(Acyltransferase)PF14829(GPAT_N) | 5 | LEU A 274LEU A 305LEU A 152ALA A 160ILE A 159 | None | 1.03A | 2bxpA-1iuqA:3.2 | 2bxpA-1iuqA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k8q | TRIACYLGLYCEROLLIPASE, GASTRIC (Canis lupus) |
PF00561(Abhydrolase_1) | 5 | PHE A 121TRP A 119ARG A 106ALA A 71ALA A 265 | None | 1.25A | 2bxpA-1k8qA:undetectable | 2bxpA-1k8qA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m32 | 2-AMINOETHYLPHOSPHONATE-PYRUVATEAMINOTRANSFERASE (Salmonellaenterica) |
PF00266(Aminotran_5) | 5 | LEU A 60LEU A 46LEU A 255ALA A 254ALA A 191 | None | 1.22A | 2bxpA-1m32A:undetectable | 2bxpA-1m32A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1md7 | C1R COMPLEMENTSERINE PROTEASE (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin) | 5 | LEU A 561LEU A 475LEU A 543ALA A 542ILE A 541 | None | 1.21A | 2bxpA-1md7A:undetectable | 2bxpA-1md7A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbw | GLYCEROL DEHYDRATASEREACTIVASE BETASUBUNIT (Klebsiellapneumoniae) |
PF02288(Dehydratase_MU) | 5 | LEU B 107LEU B 74ALA B 73ILE B 64ALA B 55 | None | 1.20A | 2bxpA-1nbwB:undetectable | 2bxpA-1nbwB:12.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o60 | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Haemophilusinfluenzae) |
PF00793(DAHP_synth_1) | 5 | LEU A 236LEU A 229ALA A 230ILE A 270SER A 227 | None | 1.13A | 2bxpA-1o60A:undetectable | 2bxpA-1o60A:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9j | ALDEHYDEDEHYDROGENASE,CYTOSOLIC 1 (Elephantulusedwardii) |
PF00171(Aldedh) | 5 | LEU A 175LEU A 91ALA A 92ILE A 95ALA A 128 | None | 1.13A | 2bxpA-1o9jA:undetectable | 2bxpA-1o9jA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rq1 | HYPOTHETICAL 65.0KDA PROTEIN INCOX14-COS3INTERGENIC REGIONPRECURSOR (Saccharomycescerevisiae) |
PF04137(ERO1) | 5 | PHE A 78LEU A 289LEU A 396ALA A 369ILE A 372 | None | 1.06A | 2bxpA-1rq1A:undetectable | 2bxpA-1rq1A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s0h | HEMOGLOBIN ALPHACHAIN (Equus asinus) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ALA A 79ALA A 65 | NoneNoneHEM A 142 (-3.3A)NoneHEM A 142 (-3.6A) | 0.97A | 2bxpA-1s0hA:2.3 | 2bxpA-1s0hA:13.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 10 | PHE A 211TRP A 214LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260ALA A 261ILE A 264ALA A 291 | NoneNoneNoneNoneDKA A1003 (-4.3A)DKA A1003 (-3.7A)NoneNoneNoneCIT A2001 ( 3.9A) | 0.44A | 2bxpA-1tf0A:38.2 | 2bxpA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 9 | PHE A 211TRP A 214LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260SER A 287ALA A 291 | NoneNoneNoneNoneDKA A1003 (-4.3A)DKA A1003 (-3.7A)NoneNoneCIT A2001 ( 3.9A) | 0.62A | 2bxpA-1tf0A:38.2 | 2bxpA-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tu7 | GLUTATHIONES-TRANSFERASE 2 (Onchocercavolvulus) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | LEU A 154PHE A 90LEU A 158LEU A 125ALA A 126 | None | 1.04A | 2bxpA-1tu7A:undetectable | 2bxpA-1tu7A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wuf | HYPOTHETICAL PROTEINLIN2664 (Listeriainnocua) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A1264LEU A1120ALA A1121ILE A1124ALA A1306 | None | 1.15A | 2bxpA-1wufA:undetectable | 2bxpA-1wufA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xp8 | RECA PROTEIN (Deinococcusradiodurans) |
PF00154(RecA) | 5 | LEU A 63LEU A 235LEU A 87ALA A 88ILE A 91 | None | 1.13A | 2bxpA-1xp8A:undetectable | 2bxpA-1xp8A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zjc | AMINOPEPTIDASE AMPS (Staphylococcusaureus) |
PF02073(Peptidase_M29) | 5 | PHE A 341TRP A 154LEU A 15ALA A 12ILE A 43 | None | 1.16A | 2bxpA-1zjcA:undetectable | 2bxpA-1zjcA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ztv | HYPOTHETICAL PROTEIN (Enterococcusfaecalis) |
PF01904(DUF72) | 5 | LEU A 4PHE A 243LEU A 262ALA A 223ILE A 222 | None | 0.83A | 2bxpA-1ztvA:undetectable | 2bxpA-1ztvA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9i | ACETYL-COENZYME ACARBOXYLASE CARBOXYLTRANSFERASE SUBUNITBETA (Staphylococcusaureus) |
PF01039(Carboxyl_trans) | 5 | LEU B 161PHE B 213ALA B 110ILE B 141ALA B 164 | None | 0.99A | 2bxpA-2f9iB:undetectable | 2bxpA-2f9iB:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ihs | CG2944-PF, ISOFORM F (Drosophilamelanogaster) |
PF00622(SPRY) | 5 | LEU A 208LEU A 185ALA A 184SER A 193ALA A 204 | None | 1.23A | 2bxpA-2ihsA:undetectable | 2bxpA-2ihsA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v0s | LR1 (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | LEU A 77LEU A 54LEU A 18ILE A 15ALA A 28 | None | 1.21A | 2bxpA-2v0sA:undetectable | 2bxpA-2v0sA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vha | PERIPLASMIC BINDINGTRANSPORT PROTEIN (Shigellaflexneri) |
PF00497(SBP_bac_3) | 5 | LEU A 10PHE A 222LEU A 63ILE A 19ALA A 53 | None | 1.10A | 2bxpA-2vhaA:undetectable | 2bxpA-2vhaA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vro | ALDEHYDEDEHYDROGENASE (Paraburkholderiaxenovorans) |
PF00171(Aldedh) | 5 | PHE A 280LEU A 313LEU A 384SER A 407ALA A 409 | None | 1.12A | 2bxpA-2vroA:undetectable | 2bxpA-2vroA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdv | MYC-INDUCED NUCLEARANTIGEN (Homo sapiens) |
PF08007(Cupin_4) | 5 | LEU A 198PHE A 234LEU A 226ILE A 187ALA A 242 | NoneNoneNoneNoneOGA A 601 ( 4.2A) | 1.18A | 2bxpA-2xdvA:undetectable | 2bxpA-2xdvA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ybu | ACIDIC MAMMALIANCHITINASE (Homo sapiens) |
PF00704(Glyco_hydro_18) | 5 | PHE A 119LEU A 127LEU A 94ALA A 95ILE A 96 | None | 1.12A | 2bxpA-2ybuA:undetectable | 2bxpA-2ybuA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfh | GLUTAMATEDEHYDROGENASE,NAD-SPECIFICGLUTAMATEDEHYDROGENASE,GLUTAMATEDEHYDROGENASE (Escherichiacoli;[Clostridium]symbiosum) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | LEU A 214LEU A 318ALA A 317ILE A 316ALA A 366 | None | 1.19A | 2bxpA-2yfhA:undetectable | 2bxpA-2yfhA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ygs | APOPTOTIC PROTEASEACTIVATING FACTOR 1 (Homo sapiens) |
PF00619(CARD) | 5 | LEU A 87LEU A 75ALA A 53ILE A 57ALA A 15 | None | 1.17A | 2bxpA-2ygsA:undetectable | 2bxpA-2ygsA:8.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zf5 | GLYCEROL KINASE (Thermococcuskodakarensis) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | LEU O 166LEU O 8ALA O 17ILE O 59ALA O 54 | None | 1.04A | 2bxpA-2zf5O:undetectable | 2bxpA-2zf5O:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b89 | 16S RRNA METHYLASE (Escherichiacoli) |
PF07091(FmrO) | 5 | LEU A 176LEU A 191LEU A 194ILE A 110ALA A 200 | None | 1.01A | 2bxpA-3b89A:2.6 | 2bxpA-3b89A:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bpt | 3-HYDROXYISOBUTYRYL-COA HYDROLASE (Homo sapiens) |
PF16113(ECH_2) | 5 | PHE A 117LEU A 124LEU A 60LEU A 51ILE A 49 | None | 1.21A | 2bxpA-3bptA:1.9 | 2bxpA-3bptA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e10 | PUTATIVE NADHOXIDASE (Clostridiumacetobutylicum) |
PF00881(Nitroreductase) | 5 | LEU A 71ALA A 72ILE A 73SER A 142ALA A 110 | None | 1.04A | 2bxpA-3e10A:undetectable | 2bxpA-3e10A:14.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eq2 | PROBABLETWO-COMPONENTRESPONSE REGULATOR (Pseudomonasaeruginosa) |
PF00072(Response_reg)PF07228(SpoIIE) | 5 | LEU A 83LEU A 114LEU A 25ALA A 22ILE A 10 | None | 1.24A | 2bxpA-3eq2A:undetectable | 2bxpA-3eq2A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdj | HEMOGLOBIN SUBUNITALPHA (Camelusdromedarius) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ALA A 79ALA A 65 | NoneNoneHEM A 142 (-3.5A)NoneHEM A 142 ( 3.8A) | 0.94A | 2bxpA-3gdjA:2.4 | 2bxpA-3gdjA:14.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gxu | EPHRIN TYPE-ARECEPTOR 4 (Homo sapiens) |
PF01404(Ephrin_lbd) | 5 | PHE A 153LEU A 96PHE A 94LEU A 155SER A 168 | None | 1.21A | 2bxpA-3gxuA:undetectable | 2bxpA-3gxuA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h8w | RIBONUCLEASE H (Escherichiavirus T4) |
PF02739(5_3_exonuc_N)PF09293(RNaseH_C) | 5 | LEU A 115LEU A 68ILE A 18SER A 21ALA A 24 | None | 1.14A | 2bxpA-3h8wA:undetectable | 2bxpA-3h8wA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdy | UDP-GALACTOPYRANOSEMUTASE (Deinococcusradiodurans) |
PF03275(GLF)PF13450(NAD_binding_8) | 5 | LEU A 387LEU A 48ALA A 45ILE A 34ALA A 380 | None | 1.13A | 2bxpA-3hdyA:undetectable | 2bxpA-3hdyA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l2k | EHPF (Pantoeaagglomerans) |
PF00501(AMP-binding) | 5 | LEU A 198LEU A 216LEU A 213ILE A 233ALA A 138 | None | 1.03A | 2bxpA-3l2kA:undetectable | 2bxpA-3l2kA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1l | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Mycobacteriumtuberculosis) |
PF13561(adh_short_C2) | 5 | LEU A 102PHE A 106LEU A 141LEU A 160ALA A 159 | None | 1.05A | 2bxpA-3m1lA:undetectable | 2bxpA-3m1lA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mos | TRANSKETOLASE (Homo sapiens) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | TRP A 211PHE A 228LEU A 182ALA A 44ILE A 47 | None | 1.13A | 2bxpA-3mosA:undetectable | 2bxpA-3mosA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mq3 | PYRUVATEDEHYDROGENASEPHOSPHATASE 1 (Bos taurus) |
PF00481(PP2C) | 5 | PHE A 72LEU A 165ALA A 164SER A 95ALA A 93 | None | 1.09A | 2bxpA-3mq3A:undetectable | 2bxpA-3mq3A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8o | 6-PHOSPHOFRUCTOKINASE SUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00365(PFK) | 5 | LEU A 571LEU A 407ALA A 406ILE A 418ALA A 412 | None | 1.11A | 2bxpA-3o8oA:undetectable | 2bxpA-3o8oA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rpw | ABC TRANSPORTER (Rhodopseudomonaspalustris) |
PF13416(SBP_bac_8) | 5 | LEU A 118LEU A 285LEU A 281ILE A 105ALA A 132 | None | 1.12A | 2bxpA-3rpwA:undetectable | 2bxpA-3rpwA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tac | LIPRIN-ALPHA-2 (Homo sapiens) |
PF00536(SAM_1)PF07647(SAM_2) | 5 | LEU B1063LEU B1054LEU B1051ALA B1048ILE B1024 | None | 1.24A | 2bxpA-3tacB:undetectable | 2bxpA-3tacB:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tad | LIPRIN-ALPHA-2 (Homo sapiens) |
PF00536(SAM_1)PF07647(SAM_2) | 5 | LEU A1063LEU A1054LEU A1051ALA A1048ILE A1024 | None | 1.25A | 2bxpA-3tadA:undetectable | 2bxpA-3tadA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3teh | PHENYLALANYL-TRNASYNTHETASE ALPHACHAIN (Thermusthermophilus) |
PF01409(tRNA-synt_2d) | 5 | LEU A 244PHE A 245LEU A 110LEU A 317ALA A 323 | None | 1.15A | 2bxpA-3tehA:undetectable | 2bxpA-3tehA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tij | NUPC FAMILY PROTEIN (Vibrio cholerae) |
PF01773(Nucleos_tra2_N)PF07662(Nucleos_tra2_C)PF07670(Gate) | 5 | LEU A 406LEU A 403ALA A 400ILE A 399ALA A 367 | NoneNoneNoneDMU A 424 ( 4.7A)None | 1.24A | 2bxpA-3tijA:undetectable | 2bxpA-3tijA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u12 | USP37 PROTEIN (Homo sapiens) |
PF16674(UCH_N) | 5 | LEU A 38LEU A 74LEU A 72ALA A 92ILE A 6 | NoneNoneNoneNoneUNX A1019 ( 4.3A) | 1.09A | 2bxpA-3u12A:undetectable | 2bxpA-3u12A:11.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vb0 | GLYOXALASE/BLEOMYCINRESISTANCEPROTEIN/DIOXYGENASE (Sphingomonaswittichii) |
PF00903(Glyoxalase) | 5 | TRP A 67LEU A 9PHE A 11LEU A 145LEU A 212 | None | 1.17A | 2bxpA-3vb0A:undetectable | 2bxpA-3vb0A:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wib | HALOALKANEDEHALOGENASE (Agrobacteriumfabrum) |
PF00561(Abhydrolase_1) | 5 | PHE A 243LEU A 239LEU A 288ALA A 285ILE A 284 | None | 1.04A | 2bxpA-3wibA:undetectable | 2bxpA-3wibA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2q | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C)PF16739(CARD_2) | 5 | LEU A 57LEU A 20LEU A 84ALA A 85ILE A 88 | None | 0.95A | 2bxpA-4a2qA:3.5 | 2bxpA-4a2qA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c90 | ALPHA-GLUCURONIDASEGH115 (Bacteroidesovatus) |
PF15979(Glyco_hydro_115) | 5 | PHE A 34LEU A 46LEU A 160LEU A 72ALA A 69 | None | 1.12A | 2bxpA-4c90A:undetectable | 2bxpA-4c90A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvc | ALCOHOLDEHYDROGENASE (Pseudogluconobactersaccharoketogenes) |
PF13360(PQQ_2) | 5 | ARG A 438LEU A 456ALA A 496ILE A 497ALA A 443 | None | 1.12A | 2bxpA-4cvcA:undetectable | 2bxpA-4cvcA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dol | AT1G53520 (Arabidopsisthaliana) |
PF02431(Chalcone) | 5 | PHE A 88LEU A 70LEU A 216ALA A 213ILE A 81 | None | 1.23A | 2bxpA-4dolA:undetectable | 2bxpA-4dolA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h2l | ALPHA-GLOBIN (Peromyscusmaniculatus) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ALA A 79ALA A 65 | NoneNoneHEM A 201 (-3.4A)NoneHEM A 201 ( 3.8A) | 0.97A | 2bxpA-4h2lA:2.5 | 2bxpA-4h2lA:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3t | CRISPR-ASSOCIATEDPROTEIN, CSE1 FAMILY (Acidimicrobiumferrooxidans) |
PF09481(CRISPR_Cse1) | 5 | LEU A 15PHE A 42LEU A 29LEU A 60ALA A 59 | None | 1.10A | 2bxpA-4h3tA:2.4 | 2bxpA-4h3tA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4icq | AMINOPEPTIDASE PEPS (Streptococcuspneumoniae) |
PF02073(Peptidase_M29) | 5 | PHE A 341TRP A 154LEU A 17ALA A 14ILE A 45 | None | 1.21A | 2bxpA-4icqA:undetectable | 2bxpA-4icqA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbg | CAAXFARNESYLTRANSFERASEBETA SUBUNIT RAM1 (Aspergillusfumigatus) |
PF00432(Prenyltrans) | 5 | LEU B 491LEU B 124HIS B 129LEU B 411ALA B 437 | None | 0.90A | 2bxpA-4mbgB:undetectable | 2bxpA-4mbgB:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mfz | DBV8 PROTEIN (Nonomuraeagerenzanensis) |
no annotation | 5 | LEU A 99PHE A 110LEU A 12LEU A 20ALA A 70 | None | 1.18A | 2bxpA-4mfzA:undetectable | 2bxpA-4mfzA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mh1 | SORBOSEDEHYDROGENASE (Ketogulonicigeniumvulgare) |
PF13360(PQQ_2) | 5 | ARG A 385LEU A 403ALA A 443ILE A 444ALA A 390 | None | 1.15A | 2bxpA-4mh1A:undetectable | 2bxpA-4mh1A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnr | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Eggerthellalenta) |
PF00905(Transpeptidase) | 5 | LEU A 271PHE A 269LEU A 110ALA A 141ILE A 139 | None | 1.13A | 2bxpA-4mnrA:undetectable | 2bxpA-4mnrA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nmn | REPLICATIVE DNAHELICASE (Aquifexaeolicus) |
PF00772(DnaB)PF03796(DnaB_C) | 5 | LEU A 217LEU A 243LEU A 286ILE A 284ALA A 314 | None | 1.02A | 2bxpA-4nmnA:undetectable | 2bxpA-4nmnA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oun | MINI-RIBONUCLEASE 3 (Bacillussubtilis) |
PF00636(Ribonuclease_3) | 5 | LEU A 129PHE A 46LEU A 85ILE A 81ALA A 146 | None | 0.96A | 2bxpA-4ounA:undetectable | 2bxpA-4ounA:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0e | MAF-LIKE PROTEINYHDE (Escherichiacoli) |
PF02545(Maf) | 5 | LEU A 17LEU A 4LEU A 109ALA A 108ALA A 7 | None | 1.12A | 2bxpA-4p0eA:undetectable | 2bxpA-4p0eA:15.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 5 | LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260 | None | 0.55A | 2bxpA-4po0A:40.4 | 2bxpA-4po0A:74.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | TRP A 214LEU A 219PHE A 223HIS A 242LEU A 260ALA A 261 | None | 0.43A | 2bxpA-4po0A:40.4 | 2bxpA-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q38 | PUTATIVEUNCHARACTERIZEDPROTEIN TCP24 (Actinoplanesteichomyceticus) |
no annotation | 5 | LEU A 99PHE A 110LEU A 12LEU A 20ALA A 70 | None | 1.21A | 2bxpA-4q38A:undetectable | 2bxpA-4q38A:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r10 | PROTEIN HUMPBACK-2 (Caenorhabditiselegans) |
PF00514(Arm) | 5 | LEU A 232LEU A 165ALA A 166ILE A 169ALA A 203 | None | 0.58A | 2bxpA-4r10A:undetectable | 2bxpA-4r10A:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8f | PUTATIVEUNCHARACTERIZEDPROTEIN GBS1892 (Streptococcusagalactiae) |
PF02502(LacAB_rpiB)PF12408(DUF3666) | 5 | LEU A 134PHE A 135ALA A 4ILE A 3ALA A 110 | None | 1.15A | 2bxpA-4u8fA:undetectable | 2bxpA-4u8fA:16.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uj8 | SURFACE LAYERPROTEIN (Geobacillusstearothermophilus) |
no annotation | 5 | PHE A 863LEU A 816LEU A 787ALA A 784ILE A 846 | None | 1.10A | 2bxpA-4uj8A:undetectable | 2bxpA-4uj8A:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkj | D-LACTATEDEHYDROGENASE (Sporolactobacillusinulinus) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 203LEU A 229LEU A 243ALA A 242ALA A 219 | None | 1.16A | 2bxpA-4xkjA:undetectable | 2bxpA-4xkjA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zdn | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A 912LEU A 557LEU A 799ALA A 749ALA A 796 | None | 1.15A | 2bxpA-4zdnA:undetectable | 2bxpA-4zdnA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aa5 | NIFE-HYDROGENASESMALL SUBUNIT, HOFK (Cupriavidusnecator) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 5 | LEU A 93LEU A 129LEU A 168ALA A 165ALA A 146 | None | 1.16A | 2bxpA-5aa5A:undetectable | 2bxpA-5aa5A:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b2o | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Francisellatularensis) |
no annotation | 5 | LEU A 12LEU A 869ALA A 870ILE A 873ALA A1096 | None | 1.02A | 2bxpA-5b2oA:1.7 | 2bxpA-5b2oA:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Geobactersulfurreducens) |
PF13847(Methyltransf_31) | 5 | TRP A 241LEU A 29LEU A 33ILE A 136ALA A 109 | None | 1.23A | 2bxpA-5bp7A:undetectable | 2bxpA-5bp7A:18.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 9 | TRP A 213LEU A 218PHE A 222LEU A 237HIS A 241LEU A 259ALA A 260ILE A 263ALA A 290 | NoneNoneNonePG4 A 602 (-4.7A)PG4 A 602 (-4.0A)PG4 A 602 ( 4.5A)PG4 A 602 ( 3.9A)NonePG4 A 602 (-3.4A) | 0.56A | 2bxpA-5dqfA:41.4 | 2bxpA-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 9 | TRP A 213LEU A 218PHE A 222LEU A 237HIS A 241LEU A 259ILE A 263SER A 286ALA A 290 | NoneNoneNonePG4 A 602 (-4.7A)PG4 A 602 (-4.0A)PG4 A 602 ( 4.5A)NonePG4 A 602 (-3.9A)PG4 A 602 (-3.4A) | 0.71A | 2bxpA-5dqfA:41.4 | 2bxpA-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9a | BETA-GALACTOSIDASE (Rahnella sp. R3) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 5 | LEU A 339PHE A 641LEU A 390ALA A 397ALA A 346 | None | 1.10A | 2bxpA-5e9aA:undetectable | 2bxpA-5e9aA:21.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 9 | PHE A 211TRP A 214LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260ALA A 261ALA A 291 | None | 0.36A | 2bxpA-5ghkA:38.3 | 2bxpA-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 9 | PHE A 211TRP A 214LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260SER A 287ALA A 291 | None | 0.59A | 2bxpA-5ghkA:38.3 | 2bxpA-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdx | METALLOPEPTIDASE (Pseudomonasaeruginosa) |
PF13402(Peptidase_M60) | 5 | LEU A 349LEU A 70ALA A 67ILE A 310ALA A 379 | None | 1.17A | 2bxpA-5kdxA:1.2 | 2bxpA-5kdxA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kkg | ANCMT E72A (syntheticconstruct) |
PF04587(ADP_PFK_GK) | 5 | LEU A 366LEU A 109LEU A 106ALA A 103ILE A 102 | None | 1.01A | 2bxpA-5kkgA:undetectable | 2bxpA-5kkgA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE DELTASUBUNIT (Aromatoleumaromaticum) |
PF02538(Hydantoinase_B) | 5 | LEU A 295PHE A 343ALA A 315ILE A 314ALA A 308 | None | 1.16A | 2bxpA-5l9wA:undetectable | 2bxpA-5l9wA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0y | CELLULOSOMEANCHORING PROTEINCOHESIN REGION (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | LEU A 161PHE A 48ALA A 130ILE A 129ALA A 108 | None | 1.05A | 2bxpA-5m0yA:undetectable | 2bxpA-5m0yA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5me3 | SISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 5 | LEU A 801LEU A 852ALA A 849ILE A 848ALA A 794 | None | 1.10A | 2bxpA-5me3A:undetectable | 2bxpA-5me3A:19.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 8 | ARG A 217LEU A 218PHE A 222LEU A 237LEU A 259ALA A 260ILE A 263ALA A 290 | None | 0.81A | 2bxpA-5oriA:40.2 | 2bxpA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 8 | LEU A 218PHE A 222LEU A 237HIS A 241LEU A 259ALA A 260ILE A 263ALA A 290 | None | 0.61A | 2bxpA-5oriA:40.2 | 2bxpA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 8 | LEU A 218PHE A 222LEU A 237HIS A 241LEU A 259ILE A 263SER A 286ALA A 290 | None | 0.79A | 2bxpA-5oriA:40.2 | 2bxpA-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t0z | LIPOPROTEIN,PUTATIVE (Geobactermetallireducens) |
no annotation | 5 | ARG A 73LEU A 39LEU A 167ILE A 171ALA A 61 | None | 0.94A | 2bxpA-5t0zA:undetectable | 2bxpA-5t0zA:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tgn | UNCHARACTERIZEDPROTEIN (Sphaerobacterthermophilus) |
PF12680(SnoaL_2) | 5 | ARG A 97ALA A 47ILE A 46SER A 20ALA A 24 | None | 0.99A | 2bxpA-5tgnA:undetectable | 2bxpA-5tgnA:8.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w6l | RTXREPEAT-CONTAININGCYTOTOXIN (Vibriovulnificus) |
no annotation | 5 | LEU A3598LEU A3620HIS A3624LEU A3638ILE A3642 | LEU A3598 ( 0.6A)LEU A3620 ( 0.6A)HIS A3624 ( 1.0A)LEU A3638 ( 0.6A)ILE A3642 ( 0.7A) | 1.05A | 2bxpA-5w6lA:undetectable | 2bxpA-5w6lA:9.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvg | CHITINASE (Ostriniafurnacalis) |
no annotation | 5 | PHE A 626LEU A 634LEU A 601ALA A 602ILE A 603 | None | 1.15A | 2bxpA-5wvgA:undetectable | 2bxpA-5wvgA:9.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysm | CYTOCHROME P450 (Amycolatopsismediterranei) |
no annotation | 5 | LEU A 121PHE A 106LEU A 231LEU A 241ALA A 250 | NoneHEM A 501 (-4.6A)NoneNoneNone | 1.24A | 2bxpA-5ysmA:2.0 | 2bxpA-5ysmA:8.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 7 | PHE A 211TRP A 214LEU A 219PHE A 223LEU A 238HIS A 242ILE A 290 | None | 1.26A | 2bxpA-5yxeA:37.9 | 2bxpA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 9 | PHE A 211TRP A 214LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260ALA A 261ILE A 264 | None | 0.50A | 2bxpA-5yxeA:37.9 | 2bxpA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 9 | PHE A 211TRP A 214LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260ILE A 264SER A 287 | None | 0.67A | 2bxpA-5yxeA:37.9 | 2bxpA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b20 | GUANINENUCLEOTIDE-BINDINGPROTEING(I)/G(S)/G(T)SUBUNIT BETA-1 (Bos taurus) |
no annotation | 5 | LEU A 168PHE A 180LEU A 152LEU A 192ALA A 193 | None | 1.22A | 2bxpA-6b20A:undetectable | 2bxpA-6b20A:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b8a | DNA-BINDINGTRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
no annotation | 5 | LEU A 285PHE A 281LEU A 163ALA A 146ILE A 145 | None | 1.25A | 2bxpA-6b8aA:undetectable | 2bxpA-6b8aA:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fhs | ARP5 (Chaetomiumthermophilum) |
no annotation | 5 | PHE J 119LEU J 136PHE J 140ILE J 156ALA J 70 | None | 1.24A | 2bxpA-6fhsJ:undetectable | 2bxpA-6fhsJ:8.72 |